Page last updated: 2024-08-22

angiotensin ii and Pulmonary Hypertension

angiotensin ii has been researched along with Pulmonary Hypertension in 99 studies

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199022 (22.22)18.7374
1990's29 (29.29)18.2507
2000's18 (18.18)29.6817
2010's25 (25.25)24.3611
2020's5 (5.05)2.80

Authors

AuthorsStudies
Lin, S; Ma, H; Ye, P; Yu, WD; Zhang, AK; Zheng, YG1
Fried, ND; Gardner, JD; Gilpin, NW; Lazartigues, E; Lobell, TD; Morris, TM; Oakes, JM; Pearson, CS; Xu, J; Yue, X1
Chai, CY; Chen, IC; Dai, ZK; Hsu, JH; Lin, JY; Liu, YC; Wu, BN; Yeh, JL1
Cavasin, MA; Demos-Davies, KM; Ferguson, BS; Hu, T; Keyse, SM; Kidger, AM; Lane, RH; McKinsey, TA; McKnight, RA; Nozik, ES; Robinson, EL; Rubino, M; Stratton, MS; Weiser-Evans, MCM; Wennersten, SA1
Iqbal, M; Li, A; Li, H; Li, J; Peng, Y; Yang, X; Zhang, J; Zhang, M; Zhou, D1
Gu, S; Huang, XX; Li, JF; Liu, Y; Miao, R; Wang, C; Wang, Y; Yang, YH; Zhai, ZG; Zhang, YX; Zhong, PP1
Becirovic-Agic, M; Ericsson, M; Hultström, M; Jönsson, S; Karlsen, TV; Leh, S; Lidén, Å; Nilsson, SK; Reed, RK; Skogstrand, T; Tveitarås, MK1
Li, G; Li, X; Li, Z; Liu, A; Liu, Y; Su, J; Sun, L; Xu, Y; Zhu, Y1
Calderone, A; Chabot, A; Dupuis, J; El Khoury, N; Fiset, C; Hertig, V; Jasmin, JF; Meus, MA; Nattel, S; Naud, P; Villeneuve, L1
Duan, Z; Sun, Y; Yuan, M; Yuan, Y1
Baňasová, A; Bíbová, J; Červenka, L; Hampl, V; Herget, J; Husková, Z; Jíchová, Š; Kujal, P; Sadowski, J; Vaňourková, Z; Vernerová, Z1
Bruce, E; Espejo, A; Francis, J; Horowitz, A; Katovich, MJ; Nair, A; Oswalt, A; Raizada, MK; Rathinasabapathy, A; Shenoy, V; Steckelings, UM; Sumners, C; Unger, T1
Chichger, H; Choudhary, G; Harrington, EO; Mende, U; O'Connell, KA; Vang, A; Zhang, P1
Guo, Z; Luo, C; Luo, L; Yang, M; Ye, RS; Yuan, YM1
Congxin, H; Qingyan, Z; Shengbo, Y; Wei, H; Xiaozhan, W; Xuejun, J; Xule, W; Yanhong, T; Zixuan, D; Zongwen, G1
Chen, TT; Guo, YH; Li, JJ; Liu, YL; Shi, K; Wang, XM; Yang, S; Yang, YF1
Dai, Z; Guo, Z; Hu, W; Huang, C; Jiang, X; Tang, Y; Wang, X; Yang, B; Yu, S; Zhang, S; Zhao, Q1
Chen, L; Guo, RQ; Hu, W; Yu, SB; Zhao, QY1
Abeßer, M; Baba, HA; Dahal, BK; Gaßner, B; Kojonazarov, B; Kuhn, M; Schermuly, RT; Schuh, K; Völker, K; Werner, F1
Afzali, A; Alavi, Y; Fatemi Tabatabaie, R; Hassanpour, H; Torabi, M1
Fan, R; Feng, N; Guo, H; Jia, M; Li, J; Liang, X; Liu, M; Pei, J; Wang, Y; Yang, F; Zhang, S; Zhou, Y1
Li, M; Li, Z; Sun, X1
Chen, BY; Chen, JK; Feng, HS; Huang, XJ; Liu, LB; Qu, P; Tie, R; Yu, J; Zhao, YF; Zhu, MZ; Zhu, XX1
Li, Q; Liao, S; Liu, C; Shen, S; Wan, H; Wu, Y; Yang, K; Zhang, R; Zhao, M; Zhou, L1
An, J; Chen, L; Chen, YJ; Han, SX; He, GM; Ning, YY; Wang, T; Wen, FQ; Xu, D; Yang, T; Zhang, SF; Zhang, XH1
Balyasnikova, IV; Castellon, M; Danilov, SM; Maniatis, NA; Metzger, R; Minshall, RD; Schwartz, DE; Visintine, DJ1
Argyropoulou, E; Kaparianos, A1
Eghbali, M; Iorga, A; Matori, H; Nadadur, RD; Partow-Navid, R; Umar, S; Wong, G1
Hu, N; Jiang, XX; Li, B; Li, J; Miao, Q; Miao, S; Shi, XP; Wang, SW; Ye, MX; Zhang, J; Zhang, S1
Bogaard, HJ; de Man, FS; Guignabert, C; Handoko, ML; Vonk-Noordegraaf, A1
Hao, XQ; Kong, T; Li, J; Li, M; Niu, MF; Sun, TW; Yang, DL; Yang, Z; Zhang, SY1
Fang, X; Huang, DN; Huang, XL; Tan, JX; Wang, B1
Chang, TH; Wang, HL; Zhang, XH1
Abraham, WT; Badesch, DB; Bristow, MR; Groves, BM; Lowes, BD; Perryman, MB; Raynolds, MV; Robertson, AD; Roden, RL; Voelkel, NF; Wynne, KM; Zisman, LS1
CUMMING, GR1
Puri, P; Solari, V1
Bonnet, S; Marthan, R; Pauvert, O; Rousseau, E; Savineau, JP1
Bergmann, P; Biarent, D; Hubloue, I; Kerbaul, F; Leeman, M; Milani, GM; Naeije, R; Rondelet, B; Staroukine, M1
Brimioulle, S; Fesler, P; Hubloue, I; Kerbaul, F; Ketelslegers, JM; Motte, S; Naeije, R; Remmelink, M; Rondelet, B; Salmon, I; Van Beneden, R1
Kasanuki, H; Kawana, M; Takagi, A; Ueno, Y1
Jin, D; Katayama, H; Kishi, K; Miyazaki, M; Muramatsu, M; Takai, S; Tamai, H1
Hatano, M; Kinugawa, K; Kohmoto, O; Nagai, R; Takahashi, T; Usui, S; Yao, A1
Bartel, S; Morwinski, R; Okruhlicova, L; Schulze, W; Tribulova, N; Wallukat, G; Weismann, P1
Feng, N; Hoover, DB; Paolocci, N1
Schenk, H; Schlesinger, S; Spies, C; von Dossow, V; von Heymann, C1
Cody, RJ1
Hill, NS; Ou, LC1
Espiner, EA; Hull, FT; Ikram, H; Maslowski, AH; Nicholls, MG1
Morrell, NW; Morris, KG; Stenmark, KR1
Bertolino, F; Bessac, AM; John, GW; Jover, B; Maffre, M; Valentin, JP2
Hayashi, S; Iwai, N; Nakamura, K; Onouchi, Z; Shiraishi, I; Tokiwa, K1
Du, JB; Huang, LY; Li, SZ; Zeng, HP; Zhao, B1
Chen, W; Cheng, D; Ji, C; Tang, S; Wang, B1
Wang, S1
Cargill, RI; Lipworth, BJ1
Flueckiger, F; Horina, J; Preidler, K; Riepl, T; Saeed, M; Stiskal, MA; Szolar, DH; Watzinger, N1
Fitzpatrick, F; Goulet, JL; Höper, M; Koller, BH; Lepley, RA; Tuder, RM; Voelkel, NF; Wade, K1
Cheng, Z; Huang, Y; Tang, B1
al-Tubuly, R; Nunez, DJ; Owji, AA; Sebkhi, A; Wilkins, MR; Zhao, L1
Cargill, RI; Coutie, WJ; Kiely, DG; Lipworth, BJ; Wheeldon, NM1
Morrell, NW1
Cong, H; Li, Z; Odajima, K; Ouda, H; Takemura, H; Wei, M; Zhang, Q; Zhao, S1
Lin, Y; Ma, Y; Sun, M1
Belenkov, IuN; Chazova, IE; Martyniuk, TV; Masenko, VP; Volkov, VN1
Higham, MA; Morrell, NW; Polak, JM; Upton, PD; Wharton, J; Yacoub, MH1
Frasch, HF; Marshall, BE; Marshall, C1
Mitrovic, V; Schönburg, M; Schulz, O; Thormann, J1
Bivalacqua, TJ; Champion, HC; D'Souza, FM; Heistad, DD; Hyman, AL; Jeter, JR; Kadowitz, PJ; Ortiz, LA; Toyoda, K1
Hamada, H; Hirano, K; Kimura, H; Niimi, H; Oana, S; Terai, M1
Brunner, F1
Jeffery, TK; Wanstall, JC1
Angelini, A; Battista Ambrosio, G; Dalla Libera, L; Ravara, B; Rossini, K; Sandri, M; Thiene, G; Vescovo, G1
Belus, A; Bonnet, S; Hyvelin, JM; Marthan, R; Roux, E; Savineau, JP1
Li, G; Xu, J1
McMurtry, IF; Petrun, MD; Reeves, JT; Tucker, A1
Mukharliamov, IM; Ryff, IM1
Scott, E; Vaage, J; Wiberg, T1
McMurtry, IF; Petrun, MD; Reeves, JT1
Guo, J1
Cai, Q; Cai, Y; Zhou, X1
Cassis, LA; Fitz, R; Gillespie, MN; Painter, DJ; Rippetoe, PE; Soltis, EE1
Chen, S1
Chen, SC1
Duan, SF; Wang, TS; Zhang, ZQ1
Zen, GB1
Edelman, NH; Poiani, GJ; Riley, DJ; Tozzi, CA1
Altiere, RJ; Gillespie, MN; O'Connor, WN; Olson, JW; Reinsel, CN1
Jackson, RM; Narkates, AJ; Oparil, S1
Altiere, RJ; Gillespie, MN; Olson, JW1
Bette, L; Kolloch, R; Overlack, A; Schmengler, K; Stumpe, KO1
Gore, RG; Jones, R1
Maruyama, K; Mullen, M; O'Brodovich, H; Olley, PM; Rabinovitch, M; Rosenberg, HC1
Burghuber, OC; Morganroth, ML; Morris, KG; Reeves, JT; Stenmark, KR; Voelkel, NF1
Farber, HW; Hill, NS; O'Brien, RF; Rounds, S1
Hilliker, KS; Roth, RA1
Gillis, CN1
Chai, CY; Chen, HI1
Bergofsky, EH1

Reviews

7 review(s) available for angiotensin ii and Pulmonary Hypertension

ArticleYear
Local renin-angiotensin II systems, angiotensin-converting enzyme and its homologue ACE2: their potential role in the pathogenesis of chronic obstructive pulmonary diseases, pulmonary hypertension and acute respiratory distress syndrome.
    Current medicinal chemistry, 2011, Volume: 18, Issue:23

    Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Humans; Hypertension, Pulmonary; Peptidyl-Dipeptidase A; Pulmonary Disease, Chronic Obstructive; Renin-Angiotensin System; Severe Acute Respiratory Syndrome

2011
Neurohormonal axis in patients with pulmonary arterial hypertension: friend or foe?
    American journal of respiratory and critical care medicine, 2013, Jan-01, Volume: 187, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Heart Atria; Humans; Hypertension, Pulmonary; Neurotransmitter Agents; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System

2013
Haemodynamic responses to specific renin-angiotensin inhibitors in hypertension and congestive heart failure. A review.
    Drugs, 1984, Volume: 28, Issue:2

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Dipeptides; Enalapril; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Kinetics; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Renin; Renin-Angiotensin System; Teprotide

1984
The role of the renin-angiotensin and natriuretic peptide systems in the pulmonary vasculature.
    British journal of clinical pharmacology, 1995, Volume: 40, Issue:1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Humans; Hypertension, Pulmonary; Hypoxia; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Pulmonary Circulation; Renin-Angiotensin System; Vascular Resistance; Vasoconstriction

1995
[Etiology and pathogenesis of primary pulmonary hypertension].
    Kardiologiia, 1975, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Age Factors; Angiotensin II; Appetite Depressants; Arteritis; Child; Diagnosis, Differential; Female; Heart Diseases; Hemodynamics; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Middle Aged; Mycobacterium; Pulmonary Artery; Pulmonary Circulation; Sex Factors

1975
Metabolism of vasoactive hormones by lung.
    Anesthesiology, 1973, Volume: 39, Issue:6

    Topics: Acetylcholine; Angiotensin II; Animals; Antidepressive Agents; Bradykinin; Carbon Radioisotopes; Extracorporeal Circulation; Hormones; Humans; Hypertension, Pulmonary; Lung; Microsomes; Monoamine Oxidase; Neurotransmitter Agents; Norepinephrine; Prostaglandins; Pulmonary Circulation; Serotonin; Serotonin Antagonists; Vasoconstrictor Agents; Vasodilator Agents

1973
Mechanisms underlying vasomotor regulation of regional pulmonary blood flow in normal and disease states.
    The American journal of medicine, 1974, Volume: 57, Issue:3

    Topics: Acidosis, Respiratory; Angiotensin II; Animals; Blood Pressure; Bradykinin; Catecholamines; Cats; Heroin Dependence; Histamine; Humans; Hypercapnia; Hypertension, Pulmonary; Hypoxia; Lung; Lung Diseases; Mast Cells; Pressoreceptors; Prostaglandins; Pulmonary Circulation; Pulmonary Edema; Serotonin; Sympatholytics; Vasomotor System

1974

Trials

4 trial(s) available for angiotensin ii and Pulmonary Hypertension

ArticleYear
Imidapril provides a protective effect on pulmonary hypertension induced by low ambient temperature in broiler chickens.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2014, Volume: 15, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterial Pressure; Chickens; Cold Temperature; Hypertension, Pulmonary; Imidazolidines; Lung; Peptide Fragments; Peptidyl-Dipeptidase A; Poultry Diseases; Proliferating Cell Nuclear Antigen; Pulmonary Artery

2014
Secondary pulmonary hypertension: haemodynamic effects of torasemide versus furosemide.
    Clinical drug investigation, 2008, Volume: 28, Issue:1

    Topics: Administration, Oral; Aged; Angiotensin II; Antihypertensive Agents; Cardiac Output; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Endothelin-1; Female; Furosemide; Hemodynamics; Humans; Hypertension, Pulmonary; Injections, Intravenous; Lung; Male; Middle Aged; Pilot Projects; Prospective Studies; Stroke Volume; Sulfonamides; Torsemide; Treatment Outcome

2008
Haemodynamic and endocrine effects of type 1 angiotensin II receptor blockade in patients with hypoxaemic cor pulmonale.
    Cardiovascular research, 1997, Volume: 33, Issue:1

    Topics: Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Echocardiography, Doppler, Pulsed; Female; Humans; Hypertension, Pulmonary; Imidazoles; Losartan; Lung Diseases, Obstructive; Male; Pulmonary Heart Disease; Tetrazoles; Vascular Resistance

1997
[Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2000, Volume: 20, Issue:3

    Topics: Aged; Angiotensin II; Drugs, Chinese Herbal; Endothelin-1; Female; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Vasodilator Agents

2000

Other Studies

88 other study(ies) available for angiotensin ii and Pulmonary Hypertension

ArticleYear
Upregulation of miR-335-5p Contributes to Right Ventricular Remodeling via Calumenin in Pulmonary Arterial Hypertension.
    BioMed research international, 2022, Volume: 2022

    Topics: Angiotensin II; Animals; Antagomirs; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypoxia; Mice; MicroRNAs; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Up-Regulation; Ventricular Remodeling

2022
Effects of Chronic Nicotine Inhalation on Systemic and Pulmonary Blood Pressure and Right Ventricular Remodeling in Mice.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:5

    Topics: Administration, Inhalation; Angiotensin II; Animals; Atmosphere Exposure Chambers; Blood Pressure; Cardiac Catheterization; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Mice; Mice, Inbred C57BL; Nicotine; Pulmonary Artery; Vascular Remodeling; Vascular Resistance; Ventricular Remodeling

2020
The beneficial effects of angiotensin-converting enzyme II (ACE2) activator in pulmonary hypertension secondary to left ventricular dysfunction.
    International journal of medical sciences, 2020, Volume: 17, Issue:16

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activators; Humans; Hypertension, Pulmonary; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Ventricular Dysfunction, Left

2020
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy.
    American journal of physiology. Heart and circulatory physiology, 2021, 08-01, Volume: 321, Issue:2

    Topics: Angiotensin II; Animals; Case-Control Studies; Cell Proliferation; Cells, Cultured; Dual-Specificity Phosphatases; Heart Ventricles; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; MAP Kinase Signaling System; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Vascular Remodeling; Vasoconstrictor Agents

2021
Salt-contaminated water inducing pulmonary hypertension and kidney damage by increasing Ang II concentration in broilers.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Chickens; Hypertension, Pulmonary; Kidney; Sodium Chloride; Water

2022
Renin-angiotensin system regulates pulmonary arterial smooth muscle cell migration in chronic thromboembolic pulmonary hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2018, 02-01, Volume: 314, Issue:2

    Topics: Angiotensin II; Cell Movement; Cell Proliferation; Cells, Cultured; Female; Humans; Hypertension, Pulmonary; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Pulmonary Artery; Renin; Renin-Angiotensin System; Signal Transduction; Thromboembolism

2018
Time course of decompensation after angiotensin II and high-salt diet in Balb/CJ mice suggests pulmonary hypertension-induced cardiorenal syndrome.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2019, 05-01, Volume: 316, Issue:5

    Topics: Angiotensin II; Animals; Blood Pressure; Cardio-Renal Syndrome; Diet; Heart Failure; Hypertension; Hypertension, Pulmonary; Male; Mice, Inbred BALB C; Myocardium; Sodium Chloride, Dietary; Time Factors; Water-Electrolyte Imbalance

2019
ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats.
    Lung, 2013, Volume: 191, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Cytoprotection; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Naphthalenes; Neointima; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Resorcinols; Severity of Illness Index; Time Factors; Vasodilation

2013
Nestin is a marker of lung remodeling secondary to myocardial infarction and type I diabetes in the rat.
    Journal of cellular physiology, 2015, Volume: 230, Issue:1

    Topics: Actins; Airway Remodeling; Angiotensin II; Animals; Biomarkers; Cell Differentiation; Collagen Type I; Diabetes Mellitus, Type 1; Fibroblasts; Heart Failure; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; MicroRNAs; Myocardial Contraction; Myocardial Infarction; Nestin; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin; Transforming Growth Factor beta

2015
[Effects of estrogen on ACE-Ang II-AT1 axis in ovariectomy and hypoxic pulmonary hypertension rats].
    Zhonghua yi xue za zhi, 2014, Jun-10, Volume: 94, Issue:22

    Topics: Angiotensin II; Animals; Estrogens; Female; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Ovariectomy; Oxygen; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1

2014
Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
    Physiological research, 2015, Volume: 64, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation

2015
Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis.
    British journal of pharmacology, 2015, Volume: 172, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling

2015
PKC δ and βII regulate angiotensin II-mediated fibrosis through p38: a mechanism of RV fibrosis in pulmonary hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Apr-15, Volume: 308, Issue:8

    Topics: Angiotensin II; Animals; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Collagen; Enzyme Activation; Fibroblasts; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; p38 Mitogen-Activated Protein Kinases; Protein Kinase C beta; Protein Kinase C-delta; Rats, Sprague-Dawley; Ventricular Dysfunction, Right

2015
Activation of renin-angiotensin-aldosterone system (RAAS) in the lung of smoking-induced pulmonary arterial hypertension (PAH) rats.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:2

    Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Blotting, Western; Heart Ventricles; Hypertension, Pulmonary; Losartan; Lung; Male; Peptidyl-Dipeptidase A; Rats, Sprague-Dawley; Renin-Angiotensin System; Smoking; Systole

2015
Beneficial Effects of Renal Denervation on Pulmonary Vascular Remodeling in Experimental Pulmonary Artery Hypertension.
    Revista espanola de cardiologia (English ed.), 2015, Volume: 68, Issue:7

    Topics: Angiotensin II; Animals; Collagen; Dimethylformamide; Dinoprostone; Dogs; Echocardiography; Electrocardiography; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Kidney; Lung; Male; Monocrotaline; Neurotransmitter Agents; Random Allocation; Renal Artery; Renin-Angiotensin System; Sympathectomy; Vascular Remodeling

2015
Effects of angiotensin II intervention on MMP-2, MMP-9, TIMP-1, and collagen expression in rats with pulmonary hypertension.
    Genetics and molecular research : GMR, 2015, Mar-06, Volume: 14, Issue:1

    Topics: Angiotensin II; Animals; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type IV; Disease Models, Animal; Hypertension, Pulmonary; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1

2015
[Beneficial effects of renal denervation on pulmonary vascular remodeling in experimental pulmonary artery hypertension].
    Zhonghua yi xue za zhi, 2015, Apr-14, Volume: 95, Issue:14

    Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Dogs; Echocardiography; Endothelin-1; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Kidney; Lung; Monocrotaline; Pulmonary Artery; Sympathectomy; Vascular Remodeling

2015
Renal sympathetic denervation prevents the development of pulmonary arterial hypertension and cardiac dysfunction in dogs.
    The Kaohsiung journal of medical sciences, 2015, Volume: 31, Issue:8

    Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Female; Heart; Heart Ventricles; Hypertension, Pulmonary; Kidney; Male; Pulmonary Artery; Sympathectomy; Systole; Torsion Abnormality; Ultrasonography

2015
Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice.
    Basic research in cardiology, 2016, Volume: 111, Issue:2

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelial Cells; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Lung; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Receptors, Atrial Natriuretic Factor

2016
Cardiac renin-angiotensin system (gene expression) and plasma angiotensin II in chickens with T3-induced pulmonary hypertension.
    British poultry science, 2016, Volume: 57, Issue:4

    Topics: Angiotensin II; Animals; Avian Proteins; Chickens; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Heart Ventricles; Hypertension, Pulmonary; Male; Peptidyl-Dipeptidase A; Poultry Diseases; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Triiodothyronine

2016
Role of dynorphin in hypoxic pulmonary hypertension.
    European journal of pharmacology, 2016, Nov-15, Volume: 791

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Angiotensin II; Animals; Blood Pressure; Cell Hypoxia; Cell Proliferation; Dynorphins; Endothelin-1; Gene Expression Regulation; Humans; Hypertension, Pulmonary; Lung; Male; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa

2016
Statins suppress MMP2 secretion via inactivation of RhoA/ROCK pathway in pulmonary vascular smooth muscles cells.
    European journal of pharmacology, 2008, Sep-04, Volume: 591, Issue:1-3

    Topics: Angiotensin II; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin

2008
Protective effects of vasonatrin peptide against hypobaric hypoxia-induced pulmonary hypertension in rats.
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:1

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Atmospheric Pressure; Atrial Natriuretic Factor; Disease Models, Animal; Endothelin-1; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor

2010
Role of HIF-1alpha in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:4

    Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Blotting, Western; Cell Movement; Cell Proliferation; Cells, Cultured; Chromatin Immunoprecipitation; Fluorescent Antibody Technique; Humans; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptidyl-Dipeptidase A; Pulmonary Artery; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Transcription, Genetic

2009
Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters.
    Respiratory research, 2010, Mar-31, Volume: 11

    Topics: Angiotensin II; Animals; Blotting, Western; Chymases; Cricetinae; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hypertension, Pulmonary; Hypertrophy; Immunoassay; Immunohistochemistry; Male; Oligopeptides; Pulmonary Artery; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Smad Proteins; Smoking; Time Factors; Transforming Growth Factor beta1; Up-Regulation; Ventricular Function, Right; Ventricular Pressure

2010
Reduced expression of angiotensin I-converting enzyme in caveolin-1 knockout mouse lungs.
    Microvascular research, 2010, Volume: 80, Issue:2

    Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Capillaries; Caveolin 1; Endothelial Cells; Gene Expression Regulation, Enzymologic; Hypertension, Pulmonary; Immunohistochemistry; Lung; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Perfusion; Pulmonary Artery; Signal Transduction

2010
Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 113, Issue:1

    Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Cells, Cultured; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Extracellular Matrix; Female; Fibroblasts; Hypertension, Pulmonary; Male; Membrane Proteins; Monocrotaline; Nitriles; Osteopontin; Phenols; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Ventricular Remodeling

2012
Polydatin attenuates hypoxic pulmonary hypertension and reverses remodeling through protein kinase C mechanisms.
    International journal of molecular sciences, 2012, Volume: 13, Issue:6

    Topics: Angiotensin II; Animals; Endothelins; Glucosides; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Phorbol Esters; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Vascular Remodeling

2012
[Adenosine receptors agonists mitigated PAH of rats induced by chronic hypoxia through reduction of renin activity/angiotensin II levels and increase of inducible nitric oxide synthase-nitric oxide levels].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2012, Volume: 50, Issue:10

    Topics: Adenosine; Angiotensin II; Animals; Disease Models, Animal; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Proliferating Cell Nuclear Antigen; Pulmonary Artery; Purinergic P1 Receptor Agonists; Random Allocation; Rats; Rats, Sprague-Dawley; Renin

2012
Effects of tetrandrine on smooth muscle contraction induced by mediators in pulmonary hypertension.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Angiotensin II; Animals; Antihypertensive Agents; Benzylisoquinolines; Endothelin-1; Guinea Pigs; Hypertension, Pulmonary; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Pulmonary Artery; Rats; Rats, Sprague-Dawley; SRS-A

2002
Angiotensin-converting enzyme DD genotype in patients with primary pulmonary hypertension: increased frequency and association with preserved haemodynamics.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2003, Volume: 4, Issue:1

    Topics: Adult; Angiotensin II; Female; Genotype; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Peptidyl-Dipeptidase A; Pulmonary Circulation; Ventricular Function, Right

2003
Acute hemodynamic effects of angiotensin II. Preliminary report.
    Canadian Medical Association journal, 1963, Apr-20, Volume: 88

    Topics: Angiotensin II; Cardiac Catheterization; Cardiac Output; Cyanosis; Heart Septal Defects, Ventricular; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Lung

1963
Genetic polymorphisms of angiotensin system genes in congenital diaphragmatic hernia associated with persistent pulmonary hypertension.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:3

    Topics: Alleles; Angiotensin II; Angiotensinogen; Case-Control Studies; Gene Frequency; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hypertension, Pulmonary; Infant, Newborn; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Angiotensin; Renin-Angiotensin System

2004
Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:3

    Topics: Angiotensin II; Animals; Caffeine; Calcium; Calcium Signaling; Chronic Disease; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Male; Muscle, Smooth, Vascular; Phenylephrine; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Vasoconstriction; Vasoconstrictor Agents

2004
Endogenous angiotensin II in the regulation of hypoxic pulmonary vasoconstriction in anaesthetized dogs.
    Critical care (London, England), 2004, Volume: 8, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Dogs; Enalaprilat; Endothelium, Vascular; Hypertension, Pulmonary; Hypoxia; Lung; Models, Animal; Renin-Angiotensin System; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2004
Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy.
    Circulation, 2004, Oct-12, Volume: 110, Issue:15

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Anastomosis, Surgical; Angiopoietin-1; Angiotensin II; Animals; Arterioles; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Protein Receptors, Type II; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Evaluation, Preclinical; Endothelin-1; Gene Expression Regulation; Hyperplasia; Hypertension, Pulmonary; Models, Animal; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Protein Serine-Threonine Kinases; Pulmonary Artery; Purines; Random Allocation; Receptors, Growth Factor; RNA, Messenger; Signal Transduction; Sildenafil Citrate; Subclavian Artery; Sulfones; Sus scrofa; Vascular Endothelial Growth Factor A

2004
Pulmonary hypertension during epileptic seizure with evidence of increased angiotensin II in pulmonary artery.
    Heart and vessels, 2005, Volume: 20, Issue:1

    Topics: Aged; Angiotensin II; Anticonvulsants; Catheterization, Swan-Ganz; Drug Therapy, Combination; Epilepsy; Follow-Up Studies; Humans; Hypertension, Pulmonary; Losartan; Male; Pulmonary Artery; Pulmonary Circulation; Risk Assessment; Severity of Illness Index; Treatment Outcome

2005
Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats.
    Pediatric research, 2006, Volume: 60, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Proliferation; Chymases; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Serine Endopeptidases; Tetrazoles; Tunica Media

2006
Upregulated neurohumoral factors are associated with left ventricular remodeling and poor prognosis in rats with monocrotaline-induced pulmonary arterial hypertension.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:9

    Topics: Angiotensin II; Animals; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Male; Monocrotaline; Natriuretic Peptide, Brain; Norepinephrine; Prognosis; Rats; Rats, Wistar; Up-Regulation; Ventricular Remodeling

2006
Autoantibodies against G-protein-coupled receptors modulate heart mast cells.
    Cellular & molecular immunology, 2007, Volume: 4, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Angiotensin II; Animals; Animals, Newborn; Autoantibodies; Cell Degranulation; Cell Differentiation; Cells, Cultured; Female; Humans; Hypertension; Hypertension, Pulmonary; Male; Mast Cells; Middle Aged; Myocardium; Phenylephrine; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Receptors, G-Protein-Coupled; Time Factors

2007
Forever young?: nerve growth factor, sympathetic fibers, and right ventricle pressure overload.
    Circulation research, 2007, Jun-22, Volume: 100, Issue:12

    Topics: Adrenergic Fibers; Angiotensin II; Animals; Calcium; Endothelin-1; Heart Failure; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Mice; Nerve Growth Factor; Rats; Tyrosine 3-Monooxygenase; Vasoconstriction; Ventricular Dysfunction, Right

2007
The role of pulmonary vascular responses to chronic hypoxia in the development of chronic mountain sickness in rats.
    Respiration physiology, 1984, Volume: 58, Issue:2

    Topics: Altitude Sickness; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Hypertension, Pulmonary; Hypoxia; Lung; Polycythemia; Rats; Rats, Inbred Strains; Vascular Resistance; Vasoconstriction

1984
Haemodynamic and hormonal effects of captopril in primary pulmonary hypertension.
    British heart journal, 1982, Volume: 48, Issue:6

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Potassium; Proline; Pulmonary Artery; Renin-Angiotensin System; Sodium

1982
Role of angiotensin-converting enzyme and angiotensin II in development of hypoxic pulmonary hypertension.
    The American journal of physiology, 1995, Volume: 269, Issue:4 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction

1995
[Losartan prevents pulmonary hypertension induced by a thromboxane A2 analog].
    Archives des maladies du coeur et des vaisseaux, 1994, Volume: 87, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Hypertension, Pulmonary; Imidazoles; Losartan; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Tetrazoles; Thromboxane A2; Vasoconstrictor Agents

1994
Pulmonary hypertension as a fatal complication of extrahepatic portal hypertension.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 1993, Volume: 3, Issue:6

    Topics: Angiotensin I; Angiotensin II; Child; Dinoprost; Fatal Outcome; Female; Humans; Hypertension, Portal; Hypertension, Pulmonary; Thromboxane B2

1993
Prevention of thromboxane A2 receptor-mediated pulmonary hypertension by a nonpeptide angiotensin II type 1 receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Enalapril; Fatty Acids, Unsaturated; Hematocrit; Hydrazines; Hypertension, Pulmonary; Imidazoles; Losartan; Male; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Tetrazoles; Thromboxane A2

1994
Some humoral factors and their interaction on acute hypoxic pulmonary pressor response.
    Chinese medical journal, 1994, Volume: 107, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Pressure; Dinoprost; Dogs; Female; Hypertension, Pulmonary; Hypoxia; Male; Norepinephrine; Pressoreceptors; Pulmonary Artery; Thromboxane B2

1994
[The changes in the levels of angiotensins and angiotensin converting enzyme and effects of captopril in patients with hypoxic pulmonary hypertension].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1993, Volume: 24, Issue:2

    Topics: Aged; Angiotensin I; Angiotensin II; Captopril; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Peptidyl-Dipeptidase A

1993
[The effect of captopril on hemodynamics in patients of chronic obstructive pulmonary disease with pulmonary hypertension].
    Zhonghua nei ke za zhi, 1993, Volume: 32, Issue:8

    Topics: Angiotensin II; Captopril; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Peptidyl-Dipeptidase A; Thromboxane B2

1993
Pulmonary hypertension. Response of vasoactive peptides to a nonionic contrast medium in patients undergoing pulmonary angiography.
    Investigative radiology, 1995, Volume: 30, Issue:9

    Topics: Adult; Aged; Aldosterone; Anaphylaxis; Angiography, Digital Subtraction; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Proteins; Chymases; Contrast Media; Cyclic GMP; Electrocardiography; Eosinophil Granule Proteins; Eosinophil-Derived Neurotoxin; Female; Heart Rate; Humans; Hypertension, Pulmonary; Inflammation Mediators; Iohexol; Lung; Male; Middle Aged; Myoglobin; Peptides; Peptidyl-Dipeptidase A; Renin; Ribonucleases; Serine Endopeptidases; Tryptases; Vasopressins

1995
Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats.
    The Journal of clinical investigation, 1996, Jun-01, Volume: 97, Issue:11

    Topics: 5-Lipoxygenase-Activating Proteins; Altitude; Angiotensin II; Animals; Arachidonate 5-Lipoxygenase; Cardiomegaly; Carrier Proteins; Endothelium, Vascular; Gene Expression; Hypertension, Pulmonary; Hypoxia; Immunohistochemistry; In Situ Hybridization; Indoles; Inflammation; Lipoxygenase Inhibitors; Male; Membrane Proteins; Mice; Mice, Knockout; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction

1996
[A research of acute hemodynamics and hormonal changes of intravenous captopril in patients with cor pulmonale and pulmonary hypertension].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1995, Volume: 18, Issue:5

    Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Captopril; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Injections, Intravenous; Male; Middle Aged; Pulmonary Heart Disease; Thyroxine

1995
Angiotensin II receptor expression and inhibition in the chronically hypoxic rat lung.
    British journal of pharmacology, 1996, Volume: 119, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzofurans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Nitroprusside; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Receptors, Angiotensin; Thromboxane A2

1996
Use of pulsed-wave Doppler echocardiography to measure changes in MPAP. Is further validation required?
    Chest, 1997, Volume: 111, Issue:5

    Topics: Acute Disease; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Echocardiography, Doppler, Pulsed; Heart; Humans; Hypertension, Pulmonary; Hypoxia; Imidazoles; Losartan; Lung Diseases, Obstructive; Pulmonary Artery; Pulmonary Heart Disease; Rats; Renin-Angiotensin System; Reproducibility of Results; Tetrazoles; Vasoconstriction

1997
High responsiveness of cytosolic free calcium concentration to angiotensin II in cultured pulmonary arterial myocytes from pulmonary hypertensive rats.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 97, Issue:2

    Topics: Angiotensin II; Aniline Compounds; Animals; Calcimycin; Calcium; Cells, Cultured; Cytosol; Fluorescent Dyes; Hypertension, Pulmonary; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Vasoconstrictor Agents; Xanthenes

1997
[RAAS changes due to dysfunction of pulmonary ventilation].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1996, Volume: 19, Issue:2

    Topics: Aldosterone; Angiotensin II; Bronchitis; Female; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Pulmonary Emphysema; Renin; Renin-Angiotensin System; Respiratory Function Tests

1996
[Activity of renin-angiotensin-aldosterone system (RAAS) and vasopressin level in patients with primary pulmonary hypertension].
    Terapevticheskii arkhiv, 1998, Volume: 70, Issue:4

    Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biomarkers; Female; Humans; Hypertension, Pulmonary; Immunoenzyme Techniques; Male; Middle Aged; Peptidyl-Dipeptidase A; Pulmonary Wedge Pressure; Radioimmunoassay; Renin; Renin-Angiotensin System; Vasopressins

1998
Angiotensin II stimulates proliferation of human pulmonary artery smooth muscle cells via the AT1 receptor.
    Chest, 1998, Volume: 114, Issue:1 Suppl

    Topics: Angiotensin II; Cell Division; Humans; Hypertension, Pulmonary; Muscle, Smooth, Vascular; Pulmonary Circulation; Receptors, Angiotensin

1998
Endothelin-1 is elevated in monocrotaline pulmonary hypertension.
    The American journal of physiology, 1999, Volume: 276, Issue:2

    Topics: Angiotensin II; Animals; Drug Combinations; Endothelin-1; Endothelins; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Lung; Male; Monocrotaline; Oligopeptides; omega-N-Methylarginine; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Vasoconstriction

1999
High-dose enoximone to evaluate reversibility of pulmonary hypertension: is there a diagnostic value of neurohormonal measurements?
    American heart journal, 1999, Volume: 137, Issue:5

    Topics: Angiotensin II; Atrial Natriuretic Factor; Biomarkers; Cardiac Catheterization; Catecholamines; Endothelin-1; Enoximone; Female; Heart Failure; Hemodynamics; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Peptidyl-Dipeptidase A; Phosphodiesterase Inhibitors; Prognosis; Pulmonary Artery; Pulmonary Veins; Severity of Illness Index

1999
Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses.
    Circulation research, 1999, Jun-25, Volume: 84, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenoviridae; Angiotensin II; Animals; Antimetabolites, Antineoplastic; beta-Galactosidase; Bleomycin; Blood Flow Velocity; Blood Pressure; Bradykinin; Cyclic GMP; Endothelin-1; Gene Transfer Techniques; Genes, Reporter; Hypertension, Pulmonary; Hypoxia; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Phosphodiesterase Inhibitors; Pulmonary Alveoli; Pulmonary Artery; Pulmonary Circulation; Pulmonary Wedge Pressure; Purinones; Sympathomimetics; Vasoconstrictor Agents

1999
Increased expression of mast cell chymase in the lungs of patients with congenital heart disease associated with early pulmonary vascular disease.
    American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:4

    Topics: Adult; Aged; Angiotensin II; Child, Preschool; Chymases; Heart Septal Defects; Humans; Hypertension, Pulmonary; Immunohistochemistry; Infant; Lung; Mast Cells; Middle Aged; Pulmonary Artery; Pulmonary Circulation; Serine Endopeptidases; Vascular Resistance

1999
Cardiac endothelin and big endothelin in right-heart hypertrophy due to monocrotaline-induced pulmonary hypertension in rat.
    Cardiovascular research, 1999, Volume: 44, Issue:1

    Topics: Analysis of Variance; Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelin-1; Endothelins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Myocardium; Perfusion; Poisons; Protein Precursors; Rats; Rats, Sprague-Dawley

1999
Comparison of pulmonary vascular function and structure in early and established hypoxic pulmonary hypertension in rats.
    Canadian journal of physiology and pharmacology, 2001, Volume: 79, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin I; Angiotensin II; Animals; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Organ Size; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Renin-Angiotensin System; Serotonin; Vasodilator Agents

2001
Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure.
    Circulation, 2001, May-01, Volume: 103, Issue:17

    Topics: Angiotensin II; Animals; Apoptosis; Biphenyl Compounds; Calcium Channel Blockers; Drug Evaluation, Preclinical; Gene Expression Regulation; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Infusion Pumps, Implantable; Irbesartan; Male; Monocrotaline; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Nifedipine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Tumor Necrosis Factor-alpha

2001
Effect of chronic hypoxia on agonist-induced tone and calcium signaling in rat pulmonary artery.
    American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:1

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Caffeine; Calcium; Calcium Signaling; Chronic Disease; Endothelin-1; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Indoles; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Wistar; Reference Values; Vasoconstriction; Vasodilator Agents; Vasomotor System

2001
Pulmonary vascular reactivity in the spontaneously hypertensive rat.
    Blood vessels, 1979, Volume: 16, Issue:2

    Topics: Altitude; Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiomegaly; Heart; Hematocrit; Hypertension, Pulmonary; Hypoxia; Lung; Male; Organ Size; Prostaglandins F; Rats; Vascular Resistance

1979
Release of prostaglandin-like substances during elevations of left atrial pressure in the cat.
    Acta physiologica Scandinavica, 1979, Volume: 107, Issue:2

    Topics: Angiotensin II; Animals; Atrial Function; Cats; Hemodynamics; Hydrostatic Pressure; Hypertension, Pulmonary; Indomethacin; Prostaglandin Antagonists; Prostaglandins; Pulmonary Circulation

1979
Lungs from chronically hypoxic rats have decreased pressor response to acute hypoxia.
    The American journal of physiology, 1978, Volume: 235, Issue:1

    Topics: Acclimatization; Altitude; Angiotensin II; Animals; Blood Pressure; Hypertension, Pulmonary; Hypoxia; Lung; Male; Norepinephrine; Prostaglandins F; Rats; Vasomotor System

1978
[The changes in plasma renin angiotensin and arginine vasopressin in pulmonary hypertension rats].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1992, Volume: 14, Issue:5

    Topics: Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Hypertension, Pulmonary; Hypoxia; Rats; Rats, Wistar; Renin; Renin-Angiotensin System

1992
The relationship between the changes in plasma atrial natriuretic peptide and renin angiotensin contents and hemodynamics in pulmonary hypertensive rats.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1992, Volume: 7, Issue:1

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System

1992
Angiotensin II and monocrotaline-induced pulmonary hypertension: effect of losartan (DuP 753), a nonpeptide angiotensin type 1 receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:3

    Topics: Angiotensin II; Animals; Biphenyl Compounds; Body Weight; Hypertension, Pulmonary; Imidazoles; Losartan; Male; Monocrotaline; Pressoreceptors; Rats; Rats, Inbred Strains; Renin; Tetrazoles

1992
[Effect of captopril on hypoxia-induced pulmonary hypertension in pigs].
    Zhonghua yi xue za zhi, 1991, Volume: 71, Issue:3

    Topics: Angiotensin II; Animals; Captopril; Female; Hypertension, Pulmonary; Hypoxia; Male; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Swine

1991
[Effect of captopril on the activities of angiotensin II and angiotensin converting enzyme during hypoxia induced pulmonary hypertension].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1990, Volume: 13, Issue:5

    Topics: Angiotensin II; Animals; Captopril; Female; Hypertension, Pulmonary; Hypoxia; Male; Peptidyl-Dipeptidase A; Swine

1990
[Renin-angiotensin-aldosterone system and pulmonary hemodynamics in patients with pulmonary artery hypertension].
    Zhonghua nei ke za zhi, 1990, Volume: 29, Issue:7

    Topics: Aged; Angiotensin II; Blood Pressure; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Pulmonary Artery; Renin; Renin-Angiotensin System

1990
[Hemodynamic changes and their relationship with the renin-angiotensin-aldosterone system in chronic obstructive pulmonary disease].
    Zhonghua yi xue za zhi, 1989, Volume: 69, Issue:6

    Topics: Aldosterone; Angiotensin II; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Diseases, Obstructive; Male; Middle Aged; Renin; Renin-Angiotensin System

1989
Vascular collagen affects reactivity of hypertensive pulmonary arteries of the rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:4

    Topics: Angiotensin II; Animals; Collagen; Dinoprost; Hydroxyproline; Hypertension, Pulmonary; Hypoxia; Male; Norepinephrine; Potassium Chloride; Pulmonary Artery; Rats; Rats, Inbred Strains

1989
Vascular hyperresponsiveness in perfused lungs from monocrotaline-treated rats.
    The American journal of physiology, 1986, Volume: 251, Issue:1 Pt 2

    Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Perfusion; Pulmonary Artery; Pulmonary Circulation; Pulmonary Edema; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Vasoconstriction

1986
Impaired pulmonary conversion of angiotensin I to angiotensin II in rats exposed to chronic hypoxia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Chronic Disease; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; Peptidyl-Dipeptidase A; Perfusion; Pulmonary Circulation; Rats; Rats, Inbred Strains

1986
Altered pulmonary vascular smooth muscle responsiveness in monocrotaline-induced pulmonary hypertension.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:2

    Topics: Acetylcholine; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Isoproterenol; Male; Monocrotaline; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Pulmonary Artery; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Vasoconstriction

1986
Persistent hemodynamic and clinical improvement after captopril in patients with pulmonary hypertension.
    Herz, 1986, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Angiotensin II; Captopril; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Long-Term Care; Male; Middle Aged; Pulmonary Circulation; Renin

1986
Pulmonary vascular reactivity in hyperoxic pulmonary hypertension in the rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:6

    Topics: Angiotensin II; Animals; Histamine; Hypertension, Pulmonary; In Vitro Techniques; Male; Oxygen; Perfusion; Pulmonary Circulation; Rats; Rats, Inbred Strains; Vascular Resistance; Vasoconstriction

1988
Angiotensin II prevents hypoxic pulmonary hypertension and vascular changes in rat.
    The American journal of physiology, 1988, Volume: 254, Issue:3 Pt 2

    Topics: Acute Disease; Angiotensin II; Animals; Blood Vessels; Chronic Disease; Hypertension, Pulmonary; Hypoxia; Infusions, Intravenous; Male; Pulmonary Circulation; Rats; Rats, Inbred Strains

1988
[Inhibition of hypoxic pulmonary vasoconstriction by leukotriene blockade].
    Wiener klinische Wochenschrift, 1986, Feb-21, Volume: 98, Issue:4

    Topics: Angiotensin II; Animals; Diethylcarbamazine; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Hypoxia; Male; Pulmonary Circulation; Pulmonary Wedge Pressure; Rats; Rats, Inbred Strains; SRS-A; Vasoconstriction

1986
Effects of endothelial cell injury on pulmonary vascular reactivity.
    Chest, 1985, Volume: 88, Issue:4 Suppl

    Topics: Angiotensin II; Animals; Endothelium; Hypertension, Pulmonary; Lung; Lung Diseases; Male; Muscle, Smooth, Vascular; Neutrophils; Pulmonary Edema; Rats; Rats, Inbred Strains; Thiourea

1985
Increased vascular responsiveness in lungs of rats with pulmonary hypertension induced by monocrotaline pyrrole.
    The American review of respiratory disease, 1985, Volume: 131, Issue:1

    Topics: Angiotensin II; Animals; Blood Vessels; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Male; Monocrotaline; Perfusion; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin

1985
Pulmonary adema and hemorrhage as a consequence of systemic vasoconstriction.
    The American journal of physiology, 1974, Volume: 227, Issue:1

    Topics: Angiotensin II; Animals; Bradykinin; Epinephrine; Hemorrhage; Hexamethonium Compounds; Histamine; Hypertension, Pulmonary; Intracranial Pressure; Male; Norepinephrine; Organ Size; Pentolinium Tartrate; Phenoxybenzamine; Pulmonary Edema; Rats; Serotonin; Stereotaxic Techniques; Vagotomy; Vagus Nerve; Vasoconstrictor Agents; Vasopressins

1974