angiotensin ii has been researched along with Pulmonary Arterial Remodeling in 175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 106 (60.57) | 24.3611 |
| 2020's | 69 (39.43) | 2.80 |
| Authors | Studies |
|---|---|
| Billoff, S; Bode-Böger, SM; Bornstein, SR; Deussen, A; Jarzebska, N; Kolouschek, A; Kopaliani, I; Mangoni, AA; Martens-Lobenhoffer, J; Ragavan, VN; Rodionov, RN; Weiss, N | 1 |
| Frąk, W; Franczyk, B; Kućmierz, J; Młynarska, E; Rysz, J | 1 |
| Cao, D; Chang, YZ; Du, R; Gao, F; Gao, X; Jin, X; Li, H; Li, J; Li, Y; Ling, S; Liu, C; Liu, S; Liu, Z; Song, J; Sun, W; Tan, Y; Wang, Y; Xing, W; Yang, X; Yuan, M; Zhao, D; Zhao, Y; Zhong, G | 1 |
| Alvarado-Ojeda, ZA; Arrellín-Rosas, G; Castro-Martínez, G; Cervantes-Torres, J; Costet-Mejía, A; Fragoso, G; Hernández-Téllez, B; Herrera-Ruiz, M; Jiménez-Ferrer, E; Medina-Campos, ON; Méndez-Martínez, M; Pedraza-Chaverri, J; Ramírez-Pliego, O; Rosas-Salgado, G; Santana, MA; Trejo-Moreno, C | 1 |
| Cai, X; Deng, L; Fan, G; Guo, R; Li, L; Liu, W; Ni, J; Xu, Q; Zhang, D; Zhao, Y | 1 |
| Deng, Y; Lei, J; Li, H; Li, X; Peng, L; Tuo, B; Xu, J; Zhang, W; Zou, Q | 1 |
| Geng, Z; Xiong, XQ; Ye, C; Zhang, LL; Zheng, F; Zhou, YB; Zhu, GQ | 1 |
| Li, Y; Zhang, J; Zhang, S; Zou, F | 1 |
| Brozoski, DT; Fang, S; Kumar, G; Lin, CW; Lu, KT; Mathison, AJ; Muskus Veitia, PC; Quelle, FW; Reho, JJ; Sigmund, CD; Silva, SD; Teng, BQ; Wackman, KK; Werthman, AM; Wu, J | 1 |
| Bernatchez, P; Esfandiarei, M; Milad, N; Rossi, FMV; Sauge, E; Seidman, MA; Tehrani, AY; Theret, M; Tung, LW; van Breemen, C; White, Z; Zhao, RRY | 1 |
| Couto, GK; França-Neto, A; Rossoni, LV; Xavier, FE | 1 |
| Cao, N; Chen, Z; Duan, X; Gao, C; Gong, X; Li, C; Li, Z; Luo, H; Lyu, QR; Mei, Q; Tian, M; Wang, W; Wang, Y; Wu, G; Xu, Z; Yang, J; Yang, P; Yu, J; Zeng, C; Zhang, B; Zhang, Y | 1 |
| Bai, C; Chen, J; Hui, R; Li, H; Lin, Y; Liu, J; Ping, J; Song, L; Su, M; Sun, Y; Wen, H; Xiao, N; Xu, H; Zhang, M; Zhang, Y | 1 |
| Cicalese, S; Eguchi, S; Elliott, KJ; Hashimoto, T; Okuno, K; Rizzo, V; Torimoto, K | 1 |
| Anand-Srivastava, MB; Li, Y | 1 |
| Huang, W; Huang, Z; Li, W; Liang, G; Luo, W; Shen, S; Wang, M; Wu, G | 1 |
| Cui, Q; Liu, L; Qi, J; Song, J; Yang, Y; Zhang, Y; Zhao, J | 1 |
| Cicalese, SM; Coffman, TM; Eguchi, S; Hashimoto, T; Okuno, K; Preston, K; Rizzo, V; Sparks, MA; Torimoto, K | 1 |
| Shi, X; Wang, J; Yong, S; Zhang, P; Zhou, N | 1 |
| Ahmed, AA; Ahmed, AAE; El Morsy, EM; Mohamed, SK; Nofal, S | 1 |
| Cicalese, SM; Eguchi, S; Kono, R; Kuroda, R; Marumoto, S; Okuno, K; Okuno, Y; Torimoto, K; Utsunomiya, H | 1 |
| Ding, F; Fu, J; He, Y; Tang, J; Xue, Y; Zhang, M | 1 |
| Mizuno, R; Mukohda, M; Ozaki, H | 1 |
| Du, Y; Guo, S; Ren, J; Wang, L; Wang, X; Wu, L; Xu, Y; Yang, B; Yang, S; Zhang, Y; Zhou, Y | 1 |
| Liu, J; Liu, S; Pan, W; Peng, S; Qin, JJ; Wan, J; Wang, M; Wei, C; Xu, S; Xu, Y; Ye, J; Yin, Z; Zhang, J; Zhao, M; Zheng, Z | 1 |
| Alvarado-Ojeda, ZA; Arrellín-Rosas, G; Baez Reyes, JC; Castro-Martínez, G; Cruz-Muñoz, ME; Fragoso, G; Jimenez-Ferrer, JE; Méndez-Martínez, M; Salgado, GR; Trejo-Moreno, C; Zamilpa, A | 1 |
| Gao, M; Guo, KM; Li, XY; Liu, YL; Ma, MM; Qin, L; Sun, L; Wang, YT; Xie, JW; Xue, J | 1 |
| Guan, YY; Li, FY; Li, XY; Lin, CX; Liu, CZ; Lv, XF; Ma, MM; Wang, GL | 1 |
| Geng, X; He, X; Huang, X; Li, X; Ma, S; Wang, Y; Xing, Y | 1 |
| Cai, J; Jiang, W; Li, W; Lu, Y; Peng, L; Sun, X; Yuan, H | 1 |
| Deng, F; Fang, S; Zhang, B; Zhang, Y | 1 |
| Golledge, J; Huynh, P; Jose, RJ; Krishna, SM; Lazzaroni, S; Moran, CS | 1 |
| Furgeson, SB; Jolly, AJ; Lu, S; Moulton, KS; Mutryn, MF; Nemenoff, RA; Strand, KA; Tucker, RM; Weiser-Evans, MCM | 1 |
| Cheng, Z; Fu, XM; Li, JM; Liao, XB; Peng, HL; Wu, QY; Zhang, GS; Zhao, Y; Zhou, XM; Zhou, YZ | 1 |
| Briones, AM; Egido, J; García-Redondo, AB; Orejudo, M; Rodrigues-Díez, R; Rodrigues-Diez, RR; Ruiz-Ortega, M; Salaices, M; Santos-Sanchez, L; Selgas, R; Tejera-Muñoz, A | 1 |
| Liu, Z; Shen, J; Yin, L; Yue, J | 1 |
| Fried, ND; Gardner, JD; Gilpin, NW; Lazartigues, E; Lobell, TD; Morris, TM; Oakes, JM; Pearson, CS; Xu, J; Yue, X | 1 |
| Cai, Q; Chen, Y; Chu, J; Huang, Y; Lin, S; Peng, J; Sankararaman, S; Sferra, TJ; Shen, A; Yu, N; Zhang, L | 1 |
| Cai, Z; Chen, Y; Fang, W; Fu, Y; Kong, W; Li, L; Li, Z; Sun, Y; Wang, L; Yang, L; Yao, F; Zhao, Z; Zhou, Y; Zhu, H | 1 |
| Cui, W; Guo, Y; Li, K; Pei, Y; Zhang, D | 1 |
| Alves-Lopes, R; Camargo, LL; Montezano, AC; Neves, KB; Rios, FJ; Touyz, RM | 1 |
| Cao, HL; Chi, RF; Guo, CL; Li, B; Liu, HM; Lu, ZY; Qi, J; Wang, RY; Wang, X; Yang, B; Yang, ZM | 1 |
| Cicalese, S; Eguchi, S; Elliott, KJ; Kawai, T; Okuno, K; Rizzo, V; Scalia, R | 1 |
| Kong, X; Li, P; Liu, C; Shen, Y; Wu, X; Yang, C | 1 |
| Aslanidou, L; Di Lorenzo, A; Lovric, G; Sasset, L; Stergiopulos, N; Trachet, B | 1 |
| Ding, M; Guo, S; Lao, M; Li, L; Wang, Q; Xu, Z | 1 |
| Brewer, AC; Harrison, CB; Markovinovic, A; Mayr, M; Richards, DA; Santos, CXC; Sawyer, G; Shah, AM; Trevelin, SC; Yin, X; Zhang, M; Zhang, X | 1 |
| Arrabito, E; Battistoni, A; Filippini, A; Madaro, L; Nicoletti, C; Parente, R; Savoia, C; Steckelings, UM; Touyz, RM; Volpe, M | 1 |
| Chau, LY; Chen, IM; Chen, JW; Chen, YH; Chiang, MT; Hsu, FF; Hsu, YW; Huang, PH; Leu, HB; Liu, FT; Tsai, MS | 1 |
| Cai, L; Ding, Y; Fu, W; Li, X; Shi, Z; Tang, H; Xie, T; Zhou, M | 1 |
| Guan, X; Huang, W; Liang, G; Lin, K; Luo, W; Shen, Q; Shen, S; Wang, J; Wu, G; Yan, J | 1 |
| Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X | 1 |
| Bai, L; Choi, SY; Jeong, MH; Kee, HJ; Kee, SJ; Kim, GR; Kook, H; Seok, YM | 1 |
| Eiken, O; Elia, A; Keramidas, ME; Kölegård, R; Sköldefors, H; Sundblad, P | 1 |
| Bolor-Erdene, E; Mei, Y; Tian, D; Wang, L; Zhang, S; Zhou, L | 1 |
| Dai, C; Huang, S; Huang, W; Liang, G; Qian, J; Shen, S; Wang, J; Wu, G; You, S | 1 |
| Anand-Srivastava, MB; Jain, A; Srivastava, AK; Truong, V | 1 |
| Huang, W; Liang, G; Lin, K; Shan, P; Wang, Y; Wu, G; Xu, MJ; Ye, S | 1 |
| Jeong, MH; Kee, HJ; Kee, SJ; Kim, GR; Zhao, T | 1 |
| Balakrishnan, A; Howatt, DA; Javidan, A; Jiang, W; Moorleghen, JJ; Muniappan, L; Okuyama, M; Saido, TC; Subramanian, V; Thiagarajan, D; Uchida, HA; Yang, L | 1 |
| Miller, FJ; Schickling, BM | 1 |
| Chen, C; Chen, E; Gan, L; Guan, X; He, Y; Hu, H; Jiang, W; Liu, B; Liu, D; Liu, J; Liu, L; Ma, W; Tang, S; Xin, H; Xue, J; Zhang, Y | 1 |
| Cavasin, MA; Demos-Davies, KM; Ferguson, BS; Hu, T; Keyse, SM; Kidger, AM; Lane, RH; McKinsey, TA; McKnight, RA; Nozik, ES; Robinson, EL; Rubino, M; Stratton, MS; Weiser-Evans, MCM; Wennersten, SA | 1 |
| Huang, Y; Pan, Y; Xie, C; Xie, X; Ye, F; Zhang, N | 1 |
| Gekle, M; Grossmann, C; Köhler, C; Nolze, A; Quarch, K; Ruhs, S; Strätz, N | 1 |
| Gao, PJ; Guo, YT; He, S; Li, SJ; Li, XD; Lu, X; Lu, YY; Shao, S; Wang, RQ; Zhou, HD | 1 |
| Dong, N; Klenotic, PA; Li, R; Lin, Z; Narla, G; Wang, Y; Wei, W; Xie, F; Xu, Q; Zhang, C; Zhou, X | 1 |
| Huang, S; Jia, Z; Niu, Y; Shi, W; Wang, S; Yu, J; Zhang, A; Zhang, Y; Zhou, W | 1 |
| Bar, A; Chlopicki, S; Enggaard, C; Hansen, PBL; Jasztal, A; Jensen, B; Kieronska-Rudek, A; Kij, A; Marczyk, B; Mateuszuk, L; Matyjaszczyk-Gwarda, K; Proniewski, B; Przyborowski, K; Tworzydlo, A; Walczak, M | 1 |
| Clancy, P; Crossman, DJ; Emeto, TI; Golledge, J; Jose, R; Krishna, SM; Li, J; Moxon, J; Norman, P; Seto, SW | 1 |
| Chang, BI; Cheng, TL; Kuo, CH; Lai, CH; Lee, FT; Shi, GY; Wang, KC; Wu, HL; Yang, YJ | 1 |
| Chi, C; Ge, J; Jiang, D; Li, X; Liu, H; Lu, Y; Pang, J; Peng, W; Xu, X; Xu, Y; Yan, C; Zhao, Q; Zhu, G; Zhuang, J | 1 |
| Airhart, N; Angelov, SN; Dichek, DA; Hu, JH; Shi, M; Wei, H | 1 |
| Huang, J; Li, Q; Nie, J; Wang, DW; Xu, X; Zhou, C | 1 |
| Aoki, H; Baba, O; Hasegawa, K; Horie, T; Ide, Y; Izuhara, M; Kimura, M; Kimura, T; Koyama, S; Kuwabara, Y; Minatoya, K; Nakao, T; Nakazeki, F; Nishi, H; Nishiga, M; Nishino, T; Ohno, S; Ono, K; Sakamoto, K; Sowa, N; Usami, S | 1 |
| Aslanidou, L; Fraga-Silva, RA; Piersigilli, A; Segers, P; Sordet-Dessimoz, J; Stampanoni, MFM; Stergiopulos, N; Trachet, B; Villanueva-Perez, P | 1 |
| Bakoyiannis, C; Damaskos, C; Georgopoulos, S; Liakakos, T; Moris, D; Patelis, N; Perrea, D; Schizas, D | 1 |
| Diaz-Otero, JM; Dorrance, AM; Downs, K; Fisher, C; Jackson, WF; Jaffe, IZ; Moss, ME | 1 |
| Alsiraj, Y; Blalock, E; Cassis, LA; Daugherty, A; Fleenor, B; Thatcher, SE | 1 |
| Guo, R; Han, M; Liu, J; Song, J; Sun, Y | 1 |
| Bethmann, D; Gekle, M; Hünerberg, M; Mildenberger, S; Rabe, S; Schreier, B; Wickenhauser, C | 1 |
| Alajbegovic, A; Albinsson, S; Bhattachariya, A; Boettger, T; Braun, T; Dahan, D; Ekman, M; Hellstrand, P; Hien, TT; Holmberg, J; Rippe, C; Swärd, K | 1 |
| Chen, D; Chen, Q; Kang, YM; Li, YH; Ling, L; Qi, XH; Ren, XS; Sun, HJ; Tong, Y; Zhou, H; Zhu, GQ | 1 |
| Hsu, YJ; Huang, PH; Liao, MT; Liao, WI; Lin, CY; Lin, SJ; Tsai, SH; Wang, JC | 1 |
| Collawn, JF; Dell'Italia, LJ; Ferrario, CM | 1 |
| Duan, J; Guo, J; Jou, D; Li, C; Li, S; Lin, J; Lin, L; Liu, T; Lv, J; Ma, H; Shi, W; Tao, J; Wang, Y; Yan, D; Zhai, M; Zhang, C | 1 |
| Abe, T; Lee Fujimoto, K; Mutsuga, M; Narita, Y; Oshima, H; Tokuda, Y; Uchida, W; Usui, A; Yamawaki-Ogata, A | 1 |
| Dai, RZ; Gao, F; Li, JS; Zhang, DQ; Zhang, YM | 1 |
| Baig, F; Barallobre-Barreiro, J; Barwari, T; Catibog, N; Didangelos, A; Fava, M; Jahangiri, M; Joshi, A; Lu, R; Lynch, M; Mayr, M; Mayr, U; Yin, X | 1 |
| Dai, Y; Dong, Y; Li, Z; Xiong, Y; Xu, C; Yan, Z | 1 |
| Becker, PD; Elgueta, R; Emmerson, A; Ivetic, A; Lechler, RI; Lombardi, G; Mongue-Din, H; Ortiz, C; Peng, Q; Sawyer, G; Shah, AM; Smyth, LA; Trevelin, SC | 1 |
| Brian, L; Crowley, SD; Freedman, NJ; Huang, TQ; McMahon, TJ; Miller, FJ; Nepliouev, I; Rudemiller, NP; Shenoy, SK; Stiber, JA; Wertman, V; Wu, JH; Zhang, L; Zhang, Z | 1 |
| Lu, H; Lu, J; Xu, F; Zhang, J; Zhang, Y | 1 |
| Chen, Y; Huang, T; Lin, C; Lin, M; Su, Z; Wang, J; Yuan, W | 1 |
| An, WS; Jing, LS; Li, JD; Li, ZF; Mu, Y; Xu, Y; Zhao, XX | 1 |
| Guan, XM; Li, J; Li, YX; Liu, JJ; Wang, HF; Wang, YW; Xin, H; Zhao, ZG | 1 |
| Lassègue, B; Ma, J; San Martín, A; Sutliff, RL; Weiss, D; Williams, HC | 1 |
| Chuma, M; Fujino, H; Fukushima, K; Goda, M; Horinouchi, Y; Ikeda, Y; Ikuto, R; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kondo, M; Murai, Y; Takechi, K; Tsuchiya, K; Zamami, Y | 1 |
| Chen, Q; Nie, MX; Zhao, QM | 1 |
| Dong, H; Fang, J; Li, Y; Liu, L; Ming, S | 1 |
| Li, X; Li, XX; Wang, HF; Xu, M | 1 |
| Chen, AD; Chen, D; Chen, Q; Kang, YM; Li, YH; Qiu, Y; Wang, JJ; Zang, YH; Zhang, F; Zhu, GQ | 1 |
| Bastacky, SI; Jackson, EK; Salah, E; Tofovic, SP | 1 |
| Du, YN; Gao, PJ; Han, WQ; Tang, XF; Wei, J; Wu, YJ; Xu, L; Ye, MQ | 1 |
| Lu, J; Xu, F; Zhang, J | 1 |
| Chen, T; Huang, W; Liang, G; Qian, J; Qian, Y; Wang, J; Wang, Z; Wu, G; You, S | 1 |
| Basu, R; Bouvier, M; Couvineau, P; Fischer, C; Gerard, NP; Hazra, S; Kassiri, Z; Mix, DS; Oudit, GY; Paul, M; Penninger, JM; Poglitsch, M; Shen, M; Toth, S; Vederas, JC; Wang, F; Wang, W | 1 |
| Cai, GW; Cheng, P; Ding, L; Gao, S; Hu, J; Huang, GY; Wang, L; Zhang, YX | 1 |
| Andia, ME; Bakewell, R; Botnar, RM; Lacerda, S; Lavin, B; Lorrio, S; Phinikaridou, A; Rashid, I; Smith, A | 1 |
| Cong, Z; Huang, G; Lu, Z; Qi, J; Wang, X; Xu, R; Yuan, Y | 1 |
| Dai, F; Guan, W; Liu, Z; Meng, G; Qi, Y; Yao, W; Zhang, T | 1 |
| Chen, ZY; Yao, WJ | 1 |
| Cassis, LA; Daugherty, A; Thatcher, S; Wu, C; Zhang, X | 1 |
| Cai, H; Miao, XN; Siu, KL | 1 |
| Ikeda, Y; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kihira, Y; Tamaki, T; Tomita, S; Tsuchiya, K; Ueno, M; Yamano, N | 1 |
| Bai, Y; Han, JY; He, K; Huo, ZJ; Li, Q; Li, ZG; Pan, CS; Tian, GH; Wang, CS; Wei, XH; Yang, L; Zhang, YY; Zhou, CM | 1 |
| Montezano, AC; Nguyen Dinh Cat, A; Rios, FJ; Touyz, RM | 1 |
| He, H; He, J; He, L; Song, J; Wang, T; Zhou, N | 1 |
| Acuña, S; Corthorn, J; Ortíz, R; Padilla, O; Schneider, D; Valdés, G | 1 |
| Lakatta, EG; Monticone, RE; Wang, M | 1 |
| Cui, M; Liu, Y; Tian, X; Zhao, S | 1 |
| Arendshorst, WJ; Chen, W; Goldstein, A; Harrison, DG; Itani, H; Kirabo, A; Li, CI; Madhur, MS; Norlander, AE; Saleh, MA; Shyr, Y; Thabet, SR; Trott, DW; Wu, J | 1 |
| Fu, Q; Li, X; Liu, W; Man, X; Sun, X; Wang, L; Yang, D; Yuan, W | 1 |
| Aizawa, Y; Hasebe, N; Izawa, K; Kawabe, J; Kikuchi, K; Nakagawa, N; Okada, M; Sumitomo, K | 1 |
| Fang, NY; Gao, PJ; Jin, X; Liu, CF; Meng, C; Shen, K; Wang, HY; Zhang, J | 1 |
| Bruce, E; Espejo, A; Francis, J; Horowitz, A; Katovich, MJ; Nair, A; Oswalt, A; Raizada, MK; Rathinasabapathy, A; Shenoy, V; Steckelings, UM; Sumners, C; Unger, T | 1 |
| Aguado, A; Alonso, MJ; Avendaño, MS; Briones, AM; Dixon, DA; Martínez-González, J; Martínez-Revelles, S; Orriols, M; Rodríguez, C; Salaices, M; Zhenyukh, O | 1 |
| Basu, R; Fan, D; Kassiri, Z; Lee, J; Sakamuri, SS; Shen, M; Wang, X | 1 |
| Aguado, A; Alonso, MJ; Barrús, MT; Briones, AM; Cachofeiro, V; de Batista, PR; García-Redondo, L; Hernanz, R; Martín, A; Martínez-Revelles, S; Palacios, R; Salaices, M | 1 |
| Baumbach, GL; Chan, SL; Umesalma, S | 1 |
| Calderone, A; Duquette, N; El-Hamamsy, I; Hertig, V; Tanguay, JF; Tardif, K; Villeneuve, L | 1 |
| Congxin, H; Qingyan, Z; Shengbo, Y; Wei, H; Xiaozhan, W; Xuejun, J; Xule, W; Yanhong, T; Zixuan, D; Zongwen, G | 1 |
| Eberson, LS; Larson, DF; Majeed, BA; Sanchez, PA; Secomb, TW; Tawinwung, S | 1 |
| He, C; Li, P; Su, H; Tian, K; Wan, JB; Zhang, XJ | 1 |
| Davisson, RL; Eguchi, S; Elliott, KJ; Forrester, SJ; Fukuda, Y; Kawai, T; Obama, T; Park, JY; Takayanagi, T; Tilley, DG; Tsuji, T | 1 |
| Bernstein, KE; Capdevila, JH; Dakarapu, R; Ding, Y; Falck, JR; Garcia, V; Gotlinger, K; Joseph, G; Schwartzman, ML; Shkolnik, B; Zhang, FF | 1 |
| He, M; Wen, JK; Yang, Z; Yue, LY; Zhang, M; Zhang, RN; Zhang, W; Zhang, X; Zhang, XH; Zheng, B | 1 |
| Bair, TB; Chapleau, MW; Dibbern, ME; Grumbach, IM; Ketsawatsomkron, P; Kutschke, WJ; Lamping, KG; Morgan, DA; Nuno, DW; Prasad, AM; Rahmouni, K; Sigmund, CD; Venema, AN; Weiss, RM | 1 |
| Dai, Z; Guo, Z; Hu, W; Huang, C; Jiang, X; Tang, Y; Wang, X; Yang, B; Yu, S; Zhang, S; Zhao, Q | 1 |
| Feng, D; Lai, EY; Li, L; Luo, Z; Welch, WJ; Wilcox, CS | 1 |
| Chu, CS; Hébert, MJ; Hsieh, YJ; Kuo, MC; Shih, SC; Soulez, M; Wu, SJ; Yang, YH | 1 |
| Bihl, JC; Chen, S; Chen, Y; Ma, X; Xiao, X; Zhang, C; Zhao, B; Zhao, Y | 1 |
| Bethmann, D; Gekle, M; Heise, C; Hünerberg, M; Mildenberger, S; Offermanns, S; Rabe, S; Schreier, B; Sibilia, M | 1 |
| Cheng, X; Daugherty, A; Fernandes, C; Huang, X; Johnsen, SP; Levy, BD; Liao, M; Libby, P; Lindholt, JS; Liu, CL; Ren, J; Shi, GP; Sukhova, GK; Wang, Y; Wemmelund, H; Zhang, JY; Zhou, Y | 1 |
| Cai, Z; Chu, S; Cui, M; He, B; Hu, L; Shen, L; Sun, Z; Wang, X; Yi, J | 1 |
| Barhoumi, T; Briet, M; Mian, MO; Paradis, P; Schiffrin, EL | 1 |
| Chen, J; He, P; Jiang, L; Liu, Y; Tan, N; Wei, X | 1 |
| Baumbach, GL; Chan, SL; Houwen, FK; Umesalma, S | 1 |
| Budish, RA; Chappell, MC; Hutson, DD; Kashyap, S; Lindsey, SH; Liu, L; Miller, KS; Murphy, B; Trask, AJ; Trimmer, EH; Zimmerman, MA | 1 |
| Aslanidou, L; Astolfo, A; Fraga-Silva, RA; Piersigilli, A; Segers, P; Sordet-Dessimoz, J; Stampanoni, MF; Stergiopulos, N; Trachet, B | 1 |
| Casare, FA; Casarini, DE; Costa-Pessoa, JM; Couto, GK; Fernandes, FB; Oliveira-Souza, M; Rossoni, LV; Thieme, K | 1 |
| Bellini, C; Bersi, MR; Harrison, DG; Humphrey, JD; Montaniel, KRC; Wu, J | 1 |
| An, XZ; Chen, HZ; Chen, XF; Hao, DL; Liu, DP; Luo, YX; Tang, X; Xie, XM; Zhao, X | 1 |
| Acs, N; Arbib, N; Hetthéssy, JR; Matrai, M; Mericli, M; Monos, E; Nadasy, GL; Szekacs, B; Varbiro, S | 1 |
| Ahmad, S; Cheng, CP; Collawn, JF; Dell Italia, LJ; Ferrario, CM; Groban, L; Varagic, J; Wang, H | 1 |
| Feng, Q; He, F; Hui, J; Li, Z; Liu, YM; Qu, YY; Tang, N; Wang, LM; Zhong, H | 1 |
| Grave, K; Königshausen, E; Mori, Y; Potthoff, SA; Rump, LC; Sivritas, SH; Stamer, S; Stegbauer, J; Thieme, M; Woznowski, M | 1 |
| Chen, H; Chen, Y; Chu, J; He, F; Lin, S; Peng, J; Shen, A; Xiao, F | 1 |
| Chen, J; Huang, J; Lai, J; Wang, DW; Xu, X; Zhou, C; Zhu, F | 1 |
| Haag, M; Miteva, K; Müller, I; Pappritz, K; Ringe, J; Sittinger, M; Spillmann, F; Stachelscheid, H; Tschöpe, C; Van Linthout, S | 1 |
| Eguchi, S; Elliott, KJ; Forrester, SJ; Kawai, T; Kwok, HF; Nuti, E; Obama, T; Rizzo, V; Rossello, A; Scalia, R; Takayanagi, T; Tsuji, T | 1 |
| Cho, SN; Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Kim, HS; Lin, MQ; Ryu, Y; Yu, SY | 1 |
| De Mello, W | 1 |
| Chiba, Y; Imanishi, M; Matsunaga, S; Nakagawa, T; Tamaki, T; Tomita, N; Tomita, S; Ueno, M; Yamamoto, K | 1 |
| Dibbern, ME; Grumbach, IM; Ketsawatsomkron, P; Koval, OM; Lamping, KG; Nuno, DW; Prasad, AM; Sigmund, CD; Venema, AN | 1 |
| Chen, Y; Cui, W; Du, J; Fassett, J; Li, HH; Ma, YQ; Ren, HL; Wang, L; Xia, YL; Yang, YZ; Zhao, XC; Zhou, X | 1 |
| An, SJ; Chai, XQ; Fu, JQ; Jiao, Z; Li, M; Li, X; Liu, P; Shao, TM; Zhang, J | 1 |
| Antoniak, S; Buczek, LJ; Cardenas, JC; Church, FC; Mackman, N; Pawlinski, R | 1 |
| Geng, J; Liu, Q; Lu, D; Shan, Q; Wang, K; Wang, S; Zhang, B; Zhang, Q | 1 |
| Boyer, MJ; Eguchi, S; Elliott, KJ; Forrester, SJ; Kawai, T; Obama, T; Preston, KJ; Rizzo, V; Yan, Z | 1 |
| Akerman, AW; Ikonomidis, JS; Jones, JA; Kimbrough, D; Mukherjee, R; Nadeau, EK; Ruddy, JM; Stroud, RE | 1 |
| Han, Y; Li, Y; Liu, D; Liu, H; Liu, M; Liu, Y; Peng, C; Song, H; Tian, X; Yan, C; Zhang, J; Zhang, Q; Zhang, X; Zhang, Y | 1 |
| Jiménez-Altayó, F; Jurado, A; Meissner, A; Miro, F; Planas, AM; Vila, E | 1 |
| He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM | 1 |
| Hu, N; Jiang, XX; Li, B; Li, J; Miao, Q; Miao, S; Shi, XP; Wang, SW; Ye, MX; Zhang, J; Zhang, S | 1 |
9 review(s) available for angiotensin ii and Pulmonary Arterial Remodeling
| Article | Year |
|---|---|
Molecular Interactions of Arterial Hypertension in Its Target Organs.
Topics: Angiotensin II; Animals; Arterial Pressure; Arteries; Biomarkers; Disease Susceptibility; Endoplasmic Reticulum Stress; Humans; Hypertension; Immune System; Matrix Metalloproteinases; Organ Specificity; Oxidative Stress; Reactive Oxygen Species; Renin; Vascular Remodeling | 2021 |
Role of Gi proteins in the regulation of blood pressure and vascular remodeling.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Blood Pressure; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Vascular Remodeling | 2023 |
Oxidative Stress: A Unifying Paradigm in Hypertension.
Topics: Aldosterone; Angiotensin II; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Inflammation; Intercellular Signaling Peptides and Proteins; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sex Factors; Signal Transduction; Vascular Remodeling; Vascular Stiffness; Vasoconstriction | 2020 |
Animal models in the research of abdominal aortic aneurysms development.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Female; Genetic Predisposition to Disease; Hemodynamics; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phenotype; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sus scrofa; Vascular Remodeling | 2017 |
Multifunctional Role of Chymase in Acute and Chronic Tissue Injury and Remodeling.
Topics: Acute Disease; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiovascular Diseases; Chronic Disease; Chymases; Enzyme Inhibitors; Humans; Mast Cells; Renin-Angiotensin System; Vascular Remodeling | 2018 |
[Role of Rho/ROCK in the migration of vascular smooth muscle cells].
Topics: Angiotensin II; Cell Movement; Humans; Lysophospholipids; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; rho GTP-Binding Proteins; rho-Associated Kinases; Sphingosine; Vascular Remodeling | 2013 |
Angiotensin II and vascular injury.
Topics: Angiotensin II; Animals; Atherosclerosis; Cardiovascular Diseases; Humans; Hypertension; Muscle, Smooth, Vascular; Oxidation-Reduction; Reactive Oxygen Species; Renin-Angiotensin System; Signal Transduction; Vascular Remodeling; Vascular System Injuries | 2014 |
Proinflammation of aging central arteries: a mini-review.
Topics: Aging; Angiotensin II; Animals; Arteries; Atherosclerosis; Haplorhini; Humans; Hypertension; Myocytes, Smooth Muscle; Rabbits; Rats; Signal Transduction; Tunica Intima; Tunica Media; Vascular Remodeling | 2014 |
Intracrine angiotensin II functions originate from noncanonical pathways in the human heart.
Topics: Angiotensin II; Angiotensinogen; Animals; Chymases; Heart; Humans; Myocardium; Peptide Fragments; Renin-Angiotensin System; Vascular Remodeling; Ventricular Remodeling | 2016 |
166 other study(ies) available for angiotensin ii and Pulmonary Arterial Remodeling
| Article | Year |
|---|---|
Overexpression of dimethylarginine dimethylaminohydrolase 1 protects from angiotensin II-induced cardiac hypertrophy and vascular remodeling.
Topics: Amidohydrolases; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Enzyme Induction; Fibrosis; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Transgenic; Time Factors; Vascular Remodeling; Vasodilation; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Vascular smooth muscle cell-specific miRNA-214 knockout inhibits angiotensin II-induced hypertension through upregulation of Smad7.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Movement; Cell Proliferation; Cells, Cultured; Female; Gene Knockout Techniques; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Smad7 Protein; Up-Regulation; Vascular Remodeling | 2021 |
Characterization of a murine model of endothelial dysfunction induced by chronic intraperitoneal administration of angiotensin II.
Topics: Angiotensin II; Animals; Disease Models, Animal; Endothelium, Vascular; Infusions, Parenteral; Intercellular Adhesion Molecule-1; Interleukins; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vascular Diseases; Vascular Remodeling | 2021 |
Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti-hypertension effect.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blood Pressure; Disease Models, Animal; Drugs, Chinese Herbal; Gene Knockdown Techniques; Heart Rate; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Vascular Remodeling | 2022 |
Upregulation of miR-140-5p uncouples mitochondria by targeting Bcl-xL in vascular smooth muscle cells in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Hypertension; Mice; MicroRNAs; Mitochondria; Muscle, Smooth, Vascular; Up-Regulation; Vascular Remodeling | 2022 |
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Hypertension; Ligands; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; NADPH Oxidase 1; NF-E2-Related Factor 2; Peptide Hormones; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptors, Angiotensin; Vascular Remodeling | 2022 |
DP1 (Prostaglandin D
Topics: Angiotensin II; Animals; Cells, Cultured; Fibronectins; Fibrosis; Guanine Nucleotide Exchange Factors; Hypertension; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myofibroblasts; Receptors, Immunologic; Receptors, Prostaglandin; Transcription Factors; Vascular Remodeling | 2022 |
RhoBTB1 reverses established arterial stiffness in angiotensin II-induced hypertension by promoting actin depolymerization.
Topics: Actins; Angiotensin II; Animals; Hypertension; Mice; Muscle, Smooth, Vascular; Vascular Remodeling; Vascular Stiffness | 2022 |
Pleiotropic activation of endothelial function by angiotensin II receptor blockers is crucial to their protective anti-vascular remodeling effects.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Mice; Nitric Oxide; Receptor, Angiotensin, Type 1; Telmisartan; Vascular Remodeling | 2022 |
Cyclooxygenase-2 is a critical determinant of angiotensin II-induced vascular remodeling and stiffness in resistance arteries of ouabain-treated rats.
Topics: Angiotensin II; Animals; bcl-2-Associated X Protein; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Hydrochlorothiazide; Losartan; Matrix Metalloproteinase 2; Mesenteric Arteries; Ouabain; Rats; Rats, Wistar; Reactive Oxygen Species; Vascular Remodeling; Vascular Resistance | 2022 |
LncRNA PSR Regulates Vascular Remodeling Through Encoding a Novel Protein Arteridin.
Topics: Angiotensin II; Cell Proliferation; Cells, Cultured; Chromatin; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; RNA, Long Noncoding; Transcription Factors; Vascular Remodeling | 2022 |
Oviductal Glycoprotein 1 Promotes Hypertension by Inducing Vascular Remodeling Through an Interaction With MYH9.
Topics: Angiotensin II; Animals; Cytoskeletal Proteins; Glycoproteins; Hypertension; Inflammation; Mice; Mice, Knockout; Mice, Transgenic; Myosin Heavy Chains; Vascular Remodeling | 2022 |
Endoplasmic Reticulum Chemical Chaperone 3-Hydroxy-2-Naphthoic Acid Reduces Angiotensin II-Induced Vascular Remodeling and Hypertension In Vivo and Protein Synthesis In Vitro.
Topics: Angiotensin II; Animals; Endoplasmic Reticulum; Hydroxy Acids; Hypertension; Mice; Vascular Remodeling | 2022 |
Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Chromatography, Liquid; Mice; Tandem Mass Spectrometry; Vascular Remodeling | 2023 |
Hydroxysafflower Yellow A Inhibits Vascular Adventitial Fibroblast Migration via NLRP3 Inflammasome Inhibition through Autophagy Activation.
Topics: Adventitia; Angiotensin II; Autophagy; Fibroblasts; Humans; Inflammasomes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Toll-Like Receptor 4; Vascular Remodeling | 2022 |
Angiotensin II Type 1A Receptor Expressed in Smooth Muscle Cells is Required for Hypertensive Vascular Remodeling in Mice Infused With Angiotensin II.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibrosis; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1; Vascular Remodeling | 2023 |
Imperatorin derivative OW1, a new vasoactive compound, attenuates cell proliferation and migration by inhibiting Nox1-mediated oxidative stress.
Topics: Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Mice; Myocytes, Smooth Muscle; NADPH Oxidase 1; NIH 3T3 Cells; Oxidative Stress; Rats; Reactive Oxygen Species; Vascular Remodeling | 2023 |
Effect of bempedoic acid on angiotensin-II induced hypertension and vascular tissue remodelling in renal hypertensive rats through AMPK multiple signalling pathways modulation.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension; Male; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2023 |
Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Hypertension; Mice; Mice, Inbred C57BL; Prunus; Prunus domestica; Vascular Remodeling | 2023 |
Durative sleep fragmentation with or without hypertension suppress rapid eye movement sleep and generate cerebrovascular dysfunction.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Dementia, Vascular; Hypertension; Mice; Sleep Deprivation; Sleep, REM; Vascular Remodeling | 2023 |
Emerging evidence for a cardiovascular protective effect of concentrated Japanese plum juice.
Topics: Angiotensin II; Animals; Hypertension; Mice; Peptide Hormones; Prunus; Prunus domestica; Vascular Remodeling | 2023 |
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) drives angiotensin II-induced vascular remodeling through regulating mitochondrial fragmentation.
Topics: Angiotensin II; Animals; Catalytic Domain; DNA; DNA-Activated Protein Kinase; Humans; Hypertension; Mice; Myocytes, Smooth Muscle; Rats; Vascular Remodeling | 2023 |
Resolvin E1/ChemR23 Protects Against Hypertension and Vascular Remodeling in Angiotensin II-Induced Hypertensive Mice.
Topics: Angiotensin II; Animals; Chemokines; Eicosapentaenoic Acid; Humans; Hypertension; Inflammation; Intercellular Signaling Peptides and Proteins; Mice; NF-E2-Related Factor 2; NF-kappa B; Peptide Hormones; Vascular Remodeling | 2023 |
Aqueous Fraction from
Topics: Angiotensin II; Animals; Blood Pressure; Cucumis sativus; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Peptide Hormones; Plant Components, Aerial; Proto-Oncogene Proteins c-akt; Vascular Remodeling | 2023 |
Reduction of glyoxalase 1 (GLO1) aggravates cerebrovascular remodeling via promoting the proliferation of basilar smooth muscle cells in hypertension.
Topics: Angiotensin II; Animals; Brain; Cell Proliferation; Cells, Cultured; Hypertension; Lactoylglutathione Lyase; Male; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Rats, Sprague-Dawley; Vascular Remodeling | 2019 |
Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediated TMEM16A degradation.
Topics: Acyltransferases; Angiotensin II; Animals; Anoctamin-1; Autophagy; Calcium; Cells, Cultured; Chloride Channels; Down-Regulation; Gene Knockdown Techniques; Hypertension; Male; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2020 |
Sauchinone inhibits angiotensin II-induced proliferation and migration of vascular smooth muscle cells.
Topics: Angiotensin II; Benzopyrans; Cell Movement; Cell Proliferation; Cells, Cultured; Dioxoles; Dose-Response Relationship, Drug; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Reactive Oxygen Species; Vascular Remodeling | 2020 |
Angiotensin II-Induced vascular remodeling and hypertension involves cathepsin L/V- MEK/ERK mediated mechanism.
Topics: Angiotensin II; Animals; Cathepsin L; Cathepsins; Cells, Cultured; Cysteine Endopeptidases; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Vascular Remodeling | 2020 |
Ligustrazine prevents basilar artery remodeling in two-kidney-two-clip renovascular hypertension rats via suppressing PI3K/Akt signaling.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelin-1; Hypertension, Renovascular; Ligation; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Pyrazines; Rats, Sprague-Dawley; Renal Artery; Signal Transduction; Temporal Arteries; Vascular Remodeling | 2020 |
Depletion of CD11c+ dendritic cells in apolipoprotein E-deficient mice limits angiotensin II-induced abdominal aortic aneurysm formation and growth.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; CD11 Antigens; Cholesterol; Dendritic Cells; Leukocyte Elastase; Lymphocyte Count; Male; Mice, Knockout, ApoE; Random Allocation; Vascular Remodeling | 2019 |
PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Topics: Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Fibrosis; Flow Cytometry; Gene Expression Regulation; Male; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; PTEN Phosphohydrolase; Rats; RNA; Vascular Diseases; Vascular Remodeling | 2020 |
A novel STAT3 inhibitor attenuates angiotensin II-induced abdominal aortic aneurysm progression in mice through modulating vascular inflammation and autophagy.
Topics: Aminosalicylic Acids; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Apoptosis; Autophagy; Autophagy-Related Proteins; Cells, Cultured; Disease Models, Animal; Janus Kinase 2; Male; Mice, Knockout, ApoE; NF-kappa B; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Vascular Remodeling | 2020 |
Interleukin-17A induces vascular remodeling of small arteries and blood pressure elevation.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Shape; Humans; Hypertension; Interleukin-17; Male; Mesenteric Arteries; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Vascular Remodeling; Vasoconstrictor Agents | 2020 |
A Modified Murine Abdominal Aortic Aneurysm Rupture Model Using Elastase Perfusion and Angiotensin II Infusion.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Inflammation Mediators; Male; Mice, Inbred C57BL; Pancreatic Elastase; Time Factors; Vascular Remodeling | 2020 |
Effects of Chronic Nicotine Inhalation on Systemic and Pulmonary Blood Pressure and Right Ventricular Remodeling in Mice.
Topics: Administration, Inhalation; Angiotensin II; Animals; Atmosphere Exposure Chambers; Blood Pressure; Cardiac Catheterization; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Mice; Mice, Inbred C57BL; Nicotine; Pulmonary Artery; Vascular Remodeling; Vascular Resistance; Ventricular Remodeling | 2020 |
Qingda granule inhibits angiotensin Ⅱ induced VSMCs proliferation through MAPK and PI3K/AKT pathways.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Vascular Remodeling | 2020 |
Runx2 (Runt-Related Transcription Factor 2)-Mediated Microcalcification Is a Novel Pathological Characteristic and Potential Mediator of Abdominal Aortic Aneurysm.
Topics: Adult; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Case-Control Studies; Core Binding Factor Alpha 1 Subunit; Dilatation, Pathologic; Disease Models, Animal; Durapatite; Female; Humans; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Middle Aged; Signal Transduction; Vascular Calcification; Vascular Remodeling | 2020 |
DNA N
Topics: Adenine; AlkB Homolog 1, Histone H2a Dioxygenase; Angiotensin II; Animals; DNA Methylation; DNA Repair Enzymes; Epigenesis, Genetic; Hypertension; Leukocytes; Mice; Muscle, Smooth, Vascular; Rats; Vascular Remodeling | 2020 |
Diallyl Trisulfide Suppresses Angiotensin II-Induced Vascular Remodeling Via Inhibition of Mitochondrial Fission.
Topics: Allyl Compounds; Angiotensin II; Animals; Cell Movement; Cell Plasticity; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dynamins; Hypertension; Male; Mice, Inbred C57BL; Mitochondria, Muscle; Mitochondrial Dynamics; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Phosphorylation; Reactive Oxygen Species; rho-Associated Kinases; Signal Transduction; Sulfides; Vascular Remodeling | 2020 |
78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells.
Topics: Angiotensin II; Animals; Cell Adhesion; Cell Line; Cells, Cultured; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glucose; Heat-Shock Proteins; Male; Monocytes; Muscle, Smooth, Vascular; Protein Aggregates; Proteostasis; Rats, Sprague-Dawley; Up-Regulation; Vascular Remodeling | 2020 |
Alamandine attenuates angiotensin II-induced vascular fibrosis via inhibiting p38 MAPK pathway.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertension; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling | 2020 |
Early Morphofunctional Changes in AngII-Infused Mice Contribute to Regional Onset of Aortic Aneurysm and Dissection.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortography; Computed Tomography Angiography; Dilatation, Pathologic; Disease Models, Animal; Endothelium, Vascular; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Time Factors; Vascular Remodeling; Vasoconstriction; X-Ray Microtomography | 2020 |
Caveolin‑1 modulates hypertensive vascular remodeling via regulation of the Notch pathway.
Topics: Angiotensin II; Animals; Brain; Caveolin 1; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Gene Expression Regulation; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Rats; Receptor, Notch1; Signal Transduction; Up-Regulation; Vascular Remodeling | 2020 |
Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)-Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cells, Cultured; Disease Models, Animal; Fibroblasts; Growth Differentiation Factor 6; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 2; Paracrine Communication; Signal Transduction; Vascular Remodeling | 2021 |
Mas Receptor Activation Contributes to the Improvement of Nitric Oxide Bioavailability and Vascular Remodeling During Chronic AT1R (Angiotensin Type-1 Receptor) Blockade in Experimental Hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Hypertension; Imidazoles; Mesenteric Arteries; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Tetrazoles; Vascular Remodeling; Vasodilation | 2020 |
Gal-1 (Galectin-1) Upregulation Contributes to Abdominal Aortic Aneurysm Progression by Enhancing Vascular Inflammation.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Case-Control Studies; Cells, Cultured; Cytokines; Disease Models, Animal; Disease Progression; Extracellular Matrix; Fibroblasts; Galectin 1; Humans; Inflammation Mediators; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout, ApoE; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction; Up-Regulation; Vascular Remodeling | 2021 |
Factor Xa inhibitor rivaroxaban suppresses experimental abdominal aortic aneurysm progression via attenuating aortic inflammation.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Calcium Chloride; Cell Adhesion Molecules; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Factor Xa Inhibitors; Humans; Inflammation Mediators; Male; Mice, Knockout, ApoE; Retrospective Studies; Rivaroxaban; Signal Transduction; Vascular Remodeling | 2021 |
TLR2 regulates angiotensin II-induced vascular remodeling and EndMT through NF-κB signaling.
Topics: Angiotensin II; Animals; Aorta; Endothelial Cells; Fibrosis; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Knockout; NF-kappa B; Signal Transduction; Toll-Like Receptor 2; Vascular Remodeling | 2020 |
Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Magnetic Resonance Imaging; Male; Rats, Sprague-Dawley; Time Factors; Vascular Remodeling | 2021 |
HDAC5 inhibition reduces angiotensin II-induced vascular contraction, hypertrophy, and oxidative stress in a mouse model.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; Benzamides; Cells, Cultured; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxadiazoles; Oxidative Stress; rho-Associated Kinases; rhoA GTP-Binding Protein; Vascular Remodeling; Vasoconstriction | 2021 |
Adaptation to 5 weeks of intermittent local vascular pressure increments; mechanisms to be considered in the development of primary hypertension?
Topics: Adaptation, Physiological; Adult; Angiotensin II; Arm; Arterial Pressure; Endothelin-1; Humans; Hypertension; Male; Matrix Metalloproteinase 7; Regional Blood Flow; Time Factors; Vascular Remodeling; Vascular Stiffness; Young Adult | 2021 |
NAMPT/SIRT1 Attenuate Ang II-Induced Vascular Remodeling and Vulnerability to Hypertension by Inhibiting the ROS/MAPK Pathway.
Topics: Angiotensin II; Animals; Case-Control Studies; Female; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Sirtuin 1; Vascular Remodeling | 2020 |
Myeloid differentiation 2 deficiency attenuates AngII-induced arterial vascular oxidative stress, inflammation, and remodeling.
Topics: Angiotensin II; Animals; Aorta; Gene Knockdown Techniques; Humans; In Vitro Techniques; Inflammation; Lymphocyte Antigen 96; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Reactive Oxygen Species; Vascular Remodeling; Vasoconstrictor Agents | 2021 |
Angiotensin II-induced histone deacetylase 5 phosphorylation, nuclear export, and Egr-1 expression are mediated by Akt pathway in A10 vascular smooth muscle cells.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Animals; Cell Line; Early Growth Response Protein 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Hypertrophy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2021 |
Toll-like receptor 2 signaling deficiency in cardiac cells ameliorates Ang II-induced cardiac inflammation and remodeling.
Topics: Angiotensin II; Animals; Bone Marrow Transplantation; Cell Line; Gene Knockdown Techniques; Hypertension; Immunity, Innate; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; Myocardium; Myocytes, Cardiac; Rats; Signal Transduction; Toll-Like Receptor 2; Translational Research, Biomedical; Vascular Remodeling | 2021 |
MicroRNA-212-5p and its target PAFAH1B2 suppress vascular proliferation and contraction via the downregulation of RhoA.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Angiotensin II; Animals; Antagomirs; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclin D1; Disease Models, Animal; Down-Regulation; Hypertension; MicroRNAs; Muscle Contraction; Muscle, Smooth, Vascular; Rats; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; Vascular Remodeling | 2021 |
Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice.
Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Calpain; Cells, Cultured; Cytoskeleton; Dilatation, Pathologic; Disease Models, Animal; Extracellular Matrix; Female; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Rats; Receptors, LDL; Vascular Remodeling | 2021 |
Outside-in Signaling by Adventitial Fibroblasts.
Topics: Angiotensin II; Fibroblasts; Humans; Hypertension; Muscle, Smooth, Vascular; Paracrine Communication; Vascular Remodeling | 2021 |
CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice.
Topics: ADP-ribosyl Cyclase 1; Angiotensin II; Animals; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Extracellular Vesicles; Humans; Hypertension; Membrane Glycoproteins; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Signal Transduction; Vascular Remodeling | 2021 |
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy.
Topics: Angiotensin II; Animals; Case-Control Studies; Cell Proliferation; Cells, Cultured; Dual-Specificity Phosphatases; Heart Ventricles; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; MAP Kinase Signaling System; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Vascular Remodeling; Vasoconstrictor Agents | 2021 |
CCL7 contributes to angiotensin II-induced abdominal aortic aneurysm by promoting macrophage infiltration and pro-inflammatory phenotype.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cell Differentiation; Cell Movement; Cells, Cultured; Chemokine CCL7; Human Umbilical Vein Endothelial Cells; Humans; Janus Kinase 2; Macrophages; Male; Mice; Mice, Inbred C57BL; Phenotype; Receptors, CCR1; STAT1 Transcription Factor; Vascular Remodeling | 2021 |
Calcineurin (PPP3CB) regulates angiotensin II-dependent vascular remodelling by potentiating EGFR signalling in mice.
Topics: Angiotensin II; Animals; Calcineurin; ErbB Receptors; Mice; Myocytes, Smooth Muscle; Vascular Remodeling | 2021 |
Krüppel-Like Factor 15/Interleukin 11 Axis-Mediated Adventitial Remodeling Depends on Extracellular Signal-Regulated Kinases 1 and 2 Activation in Angiotensin II-Induced Hypertension.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Thoracic; Disease Models, Animal; Fibroblasts; Fibrosis; HEK293 Cells; Humans; Hypertension; Inflammation Mediators; Interleukin-11; Kruppel-Like Transcription Factors; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2021 |
Allosteric activation of PP2A inhibits experimental abdominal aortic aneurysm.
Topics: Allosteric Regulation; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Case-Control Studies; Dilatation, Pathologic; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Extracellular Signal-Regulated MAP Kinases; Humans; Macrophages; Male; Mice; Mice, Knockout, ApoE; NF-kappa B; Protein Phosphatase 2; RAW 264.7 Cells; Vascular Remodeling | 2021 |
Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Cells, Cultured; Electrolytes; Endothelial Cells; Glycine; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Isoquinolines; Kidney Glomerulus; Male; Mice; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proteinuria; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Urine; Vascular Remodeling | 2021 |
Thrombin Inhibition Prevents Endothelial Dysfunction and Reverses 20-HETE Overproduction without Affecting Blood Pressure in Angiotensin II-Induced Hypertension in Mice.
Topics: Angiotensin II; Animals; Antithrombins; Chromatography, Liquid; Dabigatran; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Hypertension; Intercellular Adhesion Molecule-1; Male; Mice; Nitric Oxide; Tandem Mass Spectrometry; Vascular Remodeling; von Willebrand Factor | 2021 |
High serum thrombospondin-1 concentration is associated with slower abdominal aortic aneurysm growth and deficiency of thrombospondin-1 promotes angiotensin II induced aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Cells, Cultured; Collagen Type III; Disease Models, Animal; Disease Progression; Elastin; Genetic Predisposition to Disease; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Male; Matrix Metalloproteinase 9; Mice, Knockout; Odds Ratio; Phenotype; Proteolysis; Receptors, LDL; Risk Factors; Thrombospondin 1; Time Factors; Tumor Suppressor Proteins; Ultrasonography; Vascular Remodeling | 2017 |
Recombinant adeno-associated virus vector carrying the thrombomodulin lectin-like domain for the treatment of abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Cytokines; Dependovirus; Disease Models, Animal; Elastin; Genetic Therapy; Genetic Vectors; HMGB1 Protein; Macrophages; Male; Matrix Metalloproteinases; Mice, Knockout, ApoE; Oxidative Stress; Protein Domains; Receptor for Advanced Glycation End Products; Thrombomodulin; Vascular Remodeling | 2017 |
Phospholipase Cγ1 Mediates Intima Formation Through Akt-Notch1 Signaling Independent of the Phospholipase Activity.
Topics: Angiotensin II; Animals; Apoptosis; Carotid Artery Injuries; Cell Dedifferentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Phospholipase C gamma; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Rats; Receptor, Notch1; RNA Interference; Signal Transduction; Time Factors; Transfection; Vascular Remodeling | 2017 |
TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms.
Topics: Adventitia; Angiotensin II; Animals; Antibodies; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Phenotype; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Severity of Illness Index; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Transforming Growth Factor beta3; Tunica Media; Vascular Remodeling | 2017 |
Soluble Epoxide Hydrolase Inhibition Protected against Angiotensin II-induced Adventitial Remodeling.
Topics: Actins; Adventitia; Angiotensin II; Animals; Calcium; Cell Differentiation; Collagen; Epoxide Hydrolases; Mice; Phenylurea Compounds; Piperidines; Proliferating Cell Nuclear Antigen; Signal Transduction; Vascular Remodeling | 2017 |
Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Apolipoproteins E; Bone Marrow Transplantation; Calcium Chloride; Cell Line; Chemokine CCL2; Cholesterol, HDL; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Humans; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phenotype; Signal Transduction; Time Factors; Transfection; Vascular Remodeling | 2017 |
Angiotensin II infusion into ApoE-/- mice: a model for aortic dissection rather than abdominal aortic aneurysm?
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortography; Computed Tomography Angiography; Disease Models, Animal; Disease Progression; Hematoma; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Time Factors; Ultrasonography, Doppler, Pulsed; Vascular Remodeling; X-Ray Microtomography | 2017 |
Endothelial Mineralocorticoid Receptor Mediates Parenchymal Arteriole and Posterior Cerebral Artery Remodeling During Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Hypertension; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Posterior Cerebral Artery; Receptors, Mineralocorticoid; Vascular Remodeling | 2017 |
Sex Chromosome Complement Defines Diffuse Versus Focal Angiotensin II-Induced Aortic Pathology.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Phenotype; Receptors, LDL; Sex Characteristics; Sex Factors; Sex-Determining Region Y Protein; Testosterone; Vascular Remodeling; Vascular Stiffness; X Chromosome; Y Chromosome | 2018 |
Adiponectin and its receptors are involved in hypertensive vascular injury.
Topics: Adiponectin; Angiotensin II; Animals; Cell Line; Gene Expression Regulation; Hypertension; Male; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, Adiponectin; Vascular Remodeling; Vascular System Injuries | 2018 |
Deletion of the EGF receptor in vascular smooth muscle cells prevents chronic angiotensin II-induced arterial wall stiffening and media thickening.
Topics: Angiotensin II; Animals; ErbB Receptors; Hypertrophy; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Tunica Media; Vascular Remodeling; Vascular Stiffness | 2018 |
Loss of Vascular Myogenic Tone in miR-143/145 Knockout Mice Is Associated With Hypertension-Induced Vascular Lesions in Small Mesenteric Arteries.
Topics: Actin Cytoskeleton; Angiotensin II; Animals; Arterial Pressure; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Elastic Tissue; Female; Fibrosis; Gene Knockout Techniques; Hyperplasia; Hypertension; Male; Mesenteric Arteries; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Neointima; Vascular Remodeling; Vascular Resistance; Vasoconstriction | 2018 |
NLRP3 Gene Deletion Attenuates Angiotensin II-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Vascular Remodeling.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Gene Deletion; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NLR Family, Pyrin Domain-Containing 3 Protein; Vascular Remodeling | 2017 |
Fucoidan attenuates angiotensin II-induced abdominal aortic aneurysms through the inhibition of c-Jun N-terminal kinase and nuclear factor κB activation.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cells, Cultured; Collagenases; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phosphorylation; Polysaccharides; Protein Kinase Inhibitors; Signal Transduction; Transcription Factor RelA; Vascular Remodeling | 2018 |
Ursolic acid prevents angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-knockout mice.
Topics: ADAM17 Protein; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Line; Cell Proliferation; Disease Models, Animal; Elastin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Ursolic Acid; Vascular Remodeling; Wound Healing | 2018 |
The oral administration of clarithromycin prevents the progression and rupture of aortic aneurysm.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Cells, Cultured; Clarithromycin; Disease Models, Animal; Elastin; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Macrophages; Male; Matrix Metalloproteinases, Secreted; Mice, Inbred C57BL; Mice, Knockout, ApoE; NF-kappa B; Phosphorylation; Vascular Remodeling | 2018 |
Astragaloside IV inhibits Angiotensin II-stimulated proliferation of rat vascular smooth muscle cells via the regulation of CDK2 activity.
Topics: Angiotensin II; Animals; Atherosclerosis; Cell Line; Cyclin-Dependent Kinase 2; G1 Phase; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; S Phase; Saponins; Triterpenes; Vascular Remodeling | 2018 |
Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling.
Topics: ADAMTS1 Protein; ADAMTS5 Protein; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Extracellular Matrix; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, LDL; Tumor Suppressor Proteins; Vascular Remodeling; Versicans | 2018 |
Acetylshikonin attenuates angiotensin II-induced proliferation and motility of human brain smooth muscle cells by inhibiting Wnt/β-catenin signaling.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Anthraquinones; beta Catenin; Brain; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; Cerebrovascular Disorders; Depression, Chemical; Drugs, Chinese Herbal; Glycogen Synthase Kinase 3 beta; Humans; Hyperplasia; Myocytes, Smooth Muscle; Phosphorylation; Phytotherapy; Stroke; Vascular Remodeling; Wnt Signaling Pathway | 2018 |
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
Topics: Adoptive Transfer; Angiotensin II; Animals; CD4-Positive T-Lymphocytes; Female; Forkhead Transcription Factors; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Cardiovascular; Myocardium; NADPH Oxidase 2; NF-kappa B; T-Lymphocytes, Regulatory; Vascular Remodeling | 2018 |
Drebrin regulates angiotensin II-induced aortic remodelling.
Topics: Angiotensin II; Animals; Aorta; Aortic Diseases; Arterial Pressure; Cell Proliferation; Disease Models, Animal; Extracellular Matrix; HEK293 Cells; Humans; Hypertension; Inflammation Mediators; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Neuropeptides; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling | 2018 |
ClC-2 knockdown prevents cerebrovascular remodeling via inhibition of the Wnt/β-catenin signaling pathway.
Topics: Angiotensin II; Animals; Basilar Artery; beta Catenin; Cell Movement; Cell Proliferation; Chloride Channels; CLC-2 Chloride Channels; Cyclin D1; Glycogen Synthase Kinase 3 beta; Humans; Ion Transport; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; RNA Interference; RNA, Small Interfering; Vascular Remodeling; Wnt Signaling Pathway | 2018 |
Yes-associated protein mediates angiotensin II-induced vascular smooth muscle cell phenotypic modulation and hypertensive vascular remodelling.
Topics: Angiotensin II; Animals; Apoptosis Regulatory Proteins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Imidazoles; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pyridines; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling; YAP-Signaling Proteins | 2018 |
Mechanism of vasoactive peptide intermedin in vascular collagen remodeling during angiotensin II-induced hypertention.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Collagen; Disease Models, Animal; Hypertension; Mitogen-Activated Protein Kinases; Peptide Hormones; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Vascular Remodeling | 2018 |
The mechanisms of Ang II-induced hypertensive vascular remodeling under suppression of CD68 in macrophages.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Disease Models, Animal; Hypertension; Macrophages; Male; Mice; Mice, Inbred C57BL; Vascular Remodeling | 2018 |
The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Phosphoprotein Phosphatases; Transforming Growth Factor beta1; Vascular Remodeling | 2019 |
Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis.
Topics: Actins; Adventitia; Angiotensin II; Animals; Aorta; Aortic Diseases; Disease Models, Animal; Febuxostat; Fibroblasts; Fibrosis; Gout Suppressants; Hypertension; Macrophages; Male; Mice, Inbred C57BL; Transforming Growth Factor beta1; Vascular Remodeling; Xanthine Oxidase | 2019 |
Long-Term Effects of the Abdominal Aortic Aneurysm Model in Rabbits Prepared by Pancreatic Elastase Combined With Angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Hemodynamics; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pancreatic Elastase; Rabbits; Time Factors; Ultrasonography, Doppler, Color; Vascular Remodeling | 2019 |
Icariin ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting Nox2-containing NADPH oxidase activation.
Topics: Angiotensin II; Animals; Basilar Artery; Brain; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Flavonoids; Humans; Hyperplasia; Hypertension; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Phytotherapy; Rats, Sprague-Dawley; Reactive Oxygen Species; Stroke; Vascular Remodeling | 2019 |
Contribution of acid sphingomyelinase to angiotensin II-induced vascular adventitial remodeling via membrane rafts/Nox2 signal pathway.
Topics: Adventitia; Angiotensin II; Animals; Blotting, Western; Gene Silencing; Immunoprecipitation; Male; Membrane Microdomains; Microscopy, Confocal; NADPH Oxidase 2; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingomyelin Phosphodiesterase; Vascular Remodeling | 2019 |
BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cell Proliferation; Gene Knockdown Techniques; Humans; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Proto-Oncogene Proteins c-bcl-6; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Remodeling | 2019 |
2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury.
Topics: 2-Methoxyestradiol; Angiotensin II; Animals; Blood Pressure; Fibrosis; Glomerular Filtration Rate; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Kidney; Kidney Diseases; Male; Rats, Sprague-Dawley; Renin-Angiotensin System; Vascular Remodeling; Ventricular Function, Left; Ventricular Remodeling | 2019 |
Membrane raft redox signalling contributes to endothelial dysfunction and vascular remodelling of thoracic aorta in angiotensin II-infused rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Hypertension; Male; Membrane Microdomains; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling | 2019 |
Inhibition of angiotensin II-induced cerebrovascular smooth muscle cell proliferation by LRRC8A downregulation through suppressing PI3K/AKT activation.
Topics: Angiotensin II; Animals; Cell Cycle; Cell Proliferation; Cells, Cultured; Down-Regulation; Gene Expression; Humans; Male; Membrane Proteins; Mice, Inbred C57BL; Molecular Targeted Therapy; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Stroke; Vascular Remodeling | 2019 |
Schizandrin B attenuates angiotensin II induced endothelial to mesenchymal transition in vascular endothelium by suppressing NF-κB activation.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclooctanes; Cytokines; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Gene Expression Regulation; Inflammation; Lignans; Male; Mice; Mice, Inbred C57BL; NF-kappa B p50 Subunit; Oxidative Stress; Phenotype; Polycyclic Compounds; Signal Transduction; Vascular Remodeling | 2019 |
Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apelin; Apoptosis; Cardiovascular Agents; Diet, High-Fat; Disease Models, Animal; Female; Gene Knockdown Techniques; Humans; Male; Mice, Transgenic; Middle Aged; Myocytes, Smooth Muscle; Neprilysin; Oxidative Stress; Peptidyl-Dipeptidase A; Phenylephrine; Primary Cell Culture; Proteolysis; Receptors, LDL; RNA, Small Interfering; Vascular Remodeling | 2019 |
The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice.
Topics: Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Cytokines; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Endothelial Cells; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Inflammation; Male; Malondialdehyde; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phytotherapy; Superoxide Dismutase; Vascular Remodeling | 2019 |
Tropoelastin: an in vivo imaging marker of dysfunctional matrix turnover during abdominal aortic dilation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Biomarkers; Contrast Media; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Extracellular Matrix; Humans; Magnetic Resonance Imaging; Mice, Knockout, ApoE; Predictive Value of Tests; Proof of Concept Study; Time Factors; Tropoelastin; Up-Regulation; Vascular Remodeling | 2020 |
Targeting HSP90 attenuates angiotensin II-induced adventitial remodelling via suppression of mitochondrial fission.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Thoracic; Benzoquinones; Calcineurin; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dynamins; Fibroblasts; HSP90 Heat-Shock Proteins; Hypertension; Lactams, Macrocyclic; Male; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Molecular Targeted Therapy; Phenotype; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling | 2020 |
RhoGDI stability is regulated by SUMOylation and ubiquitination via the AT1 receptor and participates in Ang II-induced smooth muscle proliferation and vascular remodeling.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Humans; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Proteasome Endopeptidase Complex; Protein Stability; Proteolysis; Receptor, Angiotensin, Type 1; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho Guanine Nucleotide Dissociation Inhibitor beta; Signal Transduction; Sumoylation; Ubiquitination; Vascular Remodeling | 2019 |
Castration of male mice prevents the progression of established angiotensin II-induced abdominal aortic aneurysms.
Topics: Actins; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Cells, Cultured; Collagen; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Male; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Risk Factors; Sex Factors; Testosterone; Time Factors; Ultrasonography; Vascular Remodeling | 2015 |
Recoupling of eNOS with folic acid prevents abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E null mice.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biopterins; Folic Acid; Male; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Radiography; Superoxides; Tetrahydrofolate Dehydrogenase; Ultrasonography; Vascular Remodeling | 2014 |
Smooth muscle cell-specific Hif-1α deficiency suppresses angiotensin II-induced vascular remodelling in mice.
Topics: Angiotensin II; Animals; Fibrosis; Gene Expression Regulation; Hemodynamics; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Superoxides; Vascular Remodeling | 2014 |
The ameliorating effects of long-term electroacupuncture on cardiovascular remodeling in spontaneously hypertensive rats.
Topics: Acupuncture Points; Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Collagen; Electroacupuncture; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Hypertension; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptor, Angiotensin, Type 1; Vascular Remodeling | 2014 |
Antihypertensive and vascular remodelling effects of the imperatorin derivative OW1 in renovascular hypertension rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Calcitonin Gene-Related Peptide; Collagen Type I; Collagen Type III; Disease Models, Animal; Furocoumarins; Hypertension, Renovascular; Kidney; Male; Mesenteric Arteries; Random Allocation; Rats; Rats, Sprague-Dawley; Renal Artery; Vascular Remodeling; Vasodilator Agents | 2014 |
Administration of angiotensin II and a bradykinin B2 receptor blocker in midpregnancy impairs gestational outcome in guinea pigs.
Topics: Angiotensin II; Animals; Bradykinin B2 Receptor Antagonists; Disease Models, Animal; Feasibility Studies; Female; Fetal Development; Guinea Pigs; Infusions, Subcutaneous; Kallikrein-Kinin System; Kidney; Organ Size; Placenta; Placentation; Pre-Eclampsia; Pregnancy; Pregnancy Maintenance; Pyrrolidines; Receptor, Bradykinin B2; Renin-Angiotensin System; Thiosemicarbazones; Uterus; Vascular Remodeling | 2014 |
Safflower yellow inhibits angiotensin II-induced adventitial fibroblast proliferation and migration.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Chalcone; Collagen; Fibroblasts; Gene Expression; Male; MAP Kinase Signaling System; Rats, Sprague-Dawley; Transcription Factor AP-1; Vascular Remodeling | 2014 |
Oligoclonal CD8+ T cells play a critical role in the development of hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; CD8-Positive T-Lymphocytes; Disease Models, Animal; Endothelium, Vascular; Homeodomain Proteins; Hypertension; Kidney; Major Histocompatibility Complex; Male; Mice; Mice, Knockout; Oligoclonal Bands; Vascular Remodeling | 2014 |
Effects of hydroxysafflor yellow A on proliferation and collagen synthesis of rat vascular adventitial fibroblasts induced by angiotensin II.
Topics: Actins; Adventitia; Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Chalcone; Collagen; Cytokines; Fibroblasts; Gene Expression Regulation; Male; Matrix Metalloproteinase 1; NF-kappa B; Quinones; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors; Transforming Growth Factor beta1; Vascular Remodeling | 2014 |
Impaired glutathione redox system paradoxically suppresses angiotensin II-induced vascular remodeling.
Topics: Angiotensin II; Animals; Aorta; Apoptosis; Blood Pressure; Buthionine Sulfoximine; Glutathione; Humans; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Superoxides; Vascular Remodeling | 2014 |
Adventitial gene transfer of catalase attenuates angiotensin II-induced vascular remodeling.
Topics: Adenoviridae; Adventitia; Angiotensin II; Animals; Catalase; Collagen; Fibroblasts; Gene Expression; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Macrophages; Male; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Reactive Oxygen Species; Transduction, Genetic; Transfection; Vascular Remodeling | 2015 |
Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling | 2015 |
HuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration.
Topics: Angiotensin II; Animals; Aorta; Celecoxib; Cell Movement; Cyclooxygenase 2; Drug Synergism; ELAV-Like Protein 1; Gene Expression Regulation; Humans; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA Stability; RNA, Messenger; Tenascin; Vascular Remodeling | 2015 |
Divergent roles of matrix metalloproteinase 2 in pathogenesis of thoracic aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Calcium Chloride; Cells, Cultured; Collagen; Dilatation, Pathologic; Disease Models, Animal; Elastin; Genotype; Male; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Ultrasonography; Vascular Remodeling | 2015 |
Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Oxidative Stress; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptor 4; Up-Regulation; Vascular Remodeling | 2015 |
Epidermal growth factor receptor is critical for angiotensin II-mediated hypertrophy in cerebral arterioles.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; ErbB Receptors; Female; Gene Expression Regulation; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; RNA; Signal Transduction; Vascular Remodeling | 2015 |
Nestin upregulation characterizes vascular remodeling secondary to hypertension in the rat.
Topics: Angiotensin II; Animals; Aorta; Carotid Arteries; Cells, Cultured; DNA Replication; Epidermal Growth Factor; Hypertension; Male; Muscle, Smooth, Vascular; Nestin; Rats; Rats, Sprague-Dawley; Up-Regulation; Vascular Remodeling | 2015 |
Beneficial Effects of Renal Denervation on Pulmonary Vascular Remodeling in Experimental Pulmonary Artery Hypertension.
Topics: Angiotensin II; Animals; Collagen; Dimethylformamide; Dinoprostone; Dogs; Echocardiography; Electrocardiography; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Kidney; Lung; Male; Monocrotaline; Neurotransmitter Agents; Random Allocation; Renal Artery; Renin-Angiotensin System; Sympathectomy; Vascular Remodeling | 2015 |
Effect of lysyl oxidase inhibition on angiotensin II-induced arterial hypertension, remodeling, and stiffness.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Male; Mice; Mice, Inbred C57BL; Protein-Lysine 6-Oxidase; Pulse Wave Analysis; Vascular Remodeling; Vascular Stiffness; Vasoconstrictor Agents | 2015 |
Ginsenoside Rb1 attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the JNK and p38 signaling pathways.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Apoptosis; Disease Models, Animal; Enzyme Activators; Extracellular Matrix; Ginsenosides; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Severity of Illness Index; Signal Transduction; Vascular Remodeling | 2015 |
Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Disease Models, Animal; Endoplasmic Reticulum Stress; Endothelium, Vascular; ErbB Receptors; Erlotinib Hydrochloride; Hypertension; Hypertrophy; Mice; Muscle, Smooth, Vascular; Phenylbutyrates; Quinazolines; Random Allocation; Role; Sensitivity and Specificity; Signal Transduction; Vascular Remodeling | 2015 |
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Mice, Transgenic; Microvessels; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Time Factors; Vascular Remodeling | 2015 |
TMEM16A and myocardin form a positive feedback loop that is disrupted by KLF5 during Ang II-induced vascular remodeling.
Topics: Angiotensin II; Animals; Anoctamin-1; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chloride Channels; Disease Models, Animal; Feedback, Physiological; Humans; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Neoplasm Proteins; Nuclear Proteins; Rats; Trans-Activators; Vascular Remodeling | 2015 |
Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Echocardiography; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Norepinephrine; Oligonucleotide Array Sequence Analysis; Pressoreceptors; Vascular Remodeling | 2015 |
[Beneficial effects of renal denervation on pulmonary vascular remodeling in experimental pulmonary artery hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Dogs; Echocardiography; Endothelin-1; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Kidney; Lung; Monocrotaline; Pulmonary Artery; Sympathectomy; Vascular Remodeling | 2015 |
Remodeling of Afferent Arterioles From Mice With Oxidative Stress Does Not Account for Increased Contractility but Does Limit Excessive Wall Stress.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Kidney; Mice; Mice, Knockout; Oxidative Stress; Stress, Mechanical; Superoxide Dismutase; Superoxides; Vascular Remodeling; Vasoconstriction | 2015 |
Local Augmented Angiotensinogen Secreted from Apoptotic Vascular Endothelial Cells Is a Vital Mediator of Vascular Remodelling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Apoptosis; Cell Line; Human Umbilical Vein Endothelial Cells; Humans; Lisinopril; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptidyl-Dipeptidase A; Rats; Vascular Remodeling | 2015 |
Angiotensin-(1-7) counteracts the effects of Ang II on vascular smooth muscle cells, vascular remodeling and hemorrhagic stroke: Role of the NFкB inflammatory pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Inflammation Mediators; Intracranial Hemorrhages; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Wound Healing | 2015 |
Consequences of postnatal vascular smooth muscle EGFR deletion on acute angiotensin II action.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Gene Deletion; Humans; Hypertension; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Plasminogen Activator Inhibitor 1; Signal Transduction; Time Factors; Vascular Remodeling; Vasoconstrictor Agents | 2016 |
Allergic Lung Inflammation Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice.
Topics: Angiotensin II; Animals; Anti-Allergic Agents; Antibodies, Monoclonal; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Calcium Chloride; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Immunoglobulin E; Inflammation Mediators; Lung; Macrophages; Male; Mast Cells; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Pneumonia; Respiratory Hypersensitivity; Risk Factors; Signal Transduction; Vascular Remodeling | 2016 |
Orphan Nuclear Receptor Nur77 Inhibits Angiotensin II-Induced Vascular Remodeling via Downregulation of β-Catenin.
Topics: Angiotensin II; Animals; beta Catenin; Cardiovascular Diseases; Disease Models, Animal; DNA; Down-Regulation; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Nuclear Receptor Subfamily 4, Group A, Member 1; Vascular Remodeling | 2016 |
Deficiency of T-regulatory cells exaggerates angiotensin II-induced microvascular injury by enhancing immune responses.
Topics: Adipose Tissue; Adoptive Transfer; Angiotensin II; Animals; Blood Pressure; CD4 Lymphocyte Count; Chemokine CCL2; Endothelium; Forkhead Transcription Factors; Homeodomain Proteins; Hypertension; Immunity, Innate; Kidney Cortex; Macrophages; Male; Mesenteric Arteries; Mice; Mice, Knockout; Microvessels; Monocytes; Oxidative Stress; T-Lymphocytes, Regulatory; Vascular Remodeling; Vascular Stiffness | 2016 |
Mechanism of IFN-γ in regulating OPN/Th17 pathway during vascular collagen remodeling of hypertension induced by ANG II.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Differentiation; Cells, Cultured; Collagen Type I; Collagen Type III; Disease Models, Animal; Hypertension; Inflammation Mediators; Interferon-gamma; Interleukin-10; Interleukin-23; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 1; Nuclear Receptor Subfamily 1, Group F, Member 3; Osteopontin; Procollagen; Spleen; Th17 Cells; Transforming Growth Factor beta; Vascular Remodeling | 2015 |
Roles of Caveolin-1 in Angiotensin II-Induced Hypertrophy and Inward Remodeling of Cerebral Pial Arterioles.
Topics: Angiotensin II; Animals; Arterioles; Caveolin 1; Disease Models, Animal; Gene Expression Regulation; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; RNA; Vascular Remodeling | 2016 |
GPER activation ameliorates aortic remodeling induced by salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Animals, Congenic; Aorta; Blood Pressure; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Genotype; Glycosaminoglycans; Hypertension; Lipid Peroxidation; Oxidative Stress; Phenylephrine; Quinolines; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin; Sodium Chloride, Dietary; Time Factors; Vascular Remodeling | 2016 |
Ascending Aortic Aneurysm in Angiotensin II-Infused Mice: Formation, Progression, and the Role of Focal Dissections.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; Aortic Valve Insufficiency; Aortography; Apolipoproteins E; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Elastic Tissue; Male; Mice, Inbred C57BL; Mice, Knockout; Time Factors; Ultrasonography, Doppler, Pulsed; Vascular Remodeling; X-Ray Microtomography | 2016 |
Renovascular remodeling and renal injury after extended angiotensin II infusion.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Glomerular Filtration Rate; Kidney; Losartan; Male; Natriuresis; Rats; Rats, Wistar; Renal Circulation; Vascular Remodeling; Vascular Resistance | 2016 |
Excessive Adventitial Remodeling Leads to Early Aortic Maladaptation in Angiotensin-Induced Hypertension.
Topics: Adventitia; Analysis of Variance; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mice; Mice, Inbred C57BL; Random Allocation; Stress, Physiological; Vascular Remodeling; Vascular Stiffness | 2016 |
SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity.
Topics: Angiotensin II; Animals; Cardiomegaly; Gene Knockdown Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria, Heart; Mitochondrial Proteins; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Sirtuins; Superoxide Dismutase; Vascular Remodeling; Vasoconstrictor Agents | 2017 |
Estrogen therapy may counterbalance eutrophic remodeling of coronary arteries and increase bradykinin relaxation in a rat model of menopausal hypertension.
Topics: Angiotensin II; Animals; Bradykinin; Coronary Vessels; Disease Models, Animal; Estrogen Replacement Therapy; Estrogens; Female; Hypertension; Menopause; Ovariectomy; Rats; Rats, Sprague-Dawley; Vascular Remodeling; Vasoconstrictor Agents; Vasodilator Agents | 2016 |
Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Blood Pressure; Cell Proliferation; China; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Receptors, Calcium-Sensing; Renin-Angiotensin System; Vascular Remodeling; Young Adult | 2016 |
Chronic p38 mitogen-activated protein kinase inhibition improves vascular function and remodeling in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Kidney; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Perfusion; Protein Kinase Inhibitors; S-Nitrosoglutathione; Systole; Vascular Remodeling | 2016 |
Qingxuan Jiangya Decoction Reverses Vascular Remodeling by Inducing Vascular Smooth Muscle Cell Apoptosis in Spontaneously Hypertensive Rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred SHR; Vascular Remodeling | 2016 |
CYP2J2-Derived EETs Attenuated Angiotensin II-Induced Adventitial Remodeling via Reduced Inflammatory Response.
Topics: 8,11,14-Eicosatrienoic Acid; Adventitia; Angiotensin II; Animals; Aorta; Blotting, Western; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Fibroblasts; Gene Transfer Techniques; HEK293 Cells; Humans; Inflammation Mediators; Male; Mice, Inbred C57BL; Microscopy, Fluorescence; Rats, Inbred WKY; RNA Interference; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Vascular Remodeling | 2016 |
Human Endomyocardial Biopsy Specimen-Derived Stromal Cells Modulate Angiotensin II-Induced Cardiac Remodeling.
Topics: Adult; Angiotensin II; Animals; Biopsy; Cardiomegaly; Cell Proliferation; Cell Transdifferentiation; Collagen; Female; Fibroblasts; Fibrosis; Humans; Immunomodulation; Male; Mice, Inbred C57BL; Myocardium; Myofibroblasts; Oxidative Stress; Stromal Cells; Vascular Remodeling; Ventricular Function, Left | 2016 |
Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II.
Topics: ADAM17 Protein; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; ErbB Receptors; Fibrosis; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Myocytes, Cardiac; Random Allocation; Renin-Angiotensin System; Sensitivity and Specificity; Signal Transduction; Vascular Remodeling; Ventricular Remodeling | 2016 |
Histone deacetylase and GATA-binding factor 6 regulate arterial remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cells, Cultured; DNA; GATA6 Transcription Factor; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Hypertension; Hypertrophy; Kidney; Male; Mice; Muscle, Smooth, Vascular; Phosphorylation; Pyrroles; Repressor Proteins; Vascular Remodeling | 2016 |
Intracellular renin increases the inward calcium current in smooth muscle cells of mesenteric artery of SHR. Implications for hypertension and vascular remodeling.
Topics: Amides; Angiotensin II; Animals; Calcium; Calcium Signaling; Disease Models, Animal; Fumarates; Humans; Hypertension; Mesenteric Arteries; Myocytes, Smooth Muscle; Rats; Renin; Vascular Remodeling; Verapamil | 2016 |
Hypoxia-Inducible Factor-1α in Smooth Muscle Cells Protects Against Aortic Aneurysms-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Elastic Tissue; Genetic Predisposition to Disease; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Protein-Lysine 6-Oxidase; Tropoelastin; Vascular Remodeling | 2016 |
Role of CaMKII in Ang-II-dependent small artery remodeling.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Female; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Messenger; Vascular Remodeling; Vasoconstriction | 2016 |
Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular Dysfunction.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Male; Mice; Mice, Knockout; Receptors, Interleukin-8B; Up-Regulation; Vascular Remodeling | 2016 |
Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats.
Topics: Actins; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cell Proliferation; Collagen Type I; Endothelin-1; Fibroblasts; Male; Malondialdehyde; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Plant Extracts; Rats, Inbred SHR; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Salvia miltiorrhiza; Smad7 Protein; Superoxide Dismutase; Systole; Transforming Growth Factor beta1; Vascular Remodeling; Water | 2016 |
Protease-Activated Receptor 1 Contributes to Angiotensin II-Induced Cardiovascular Remodeling and Inflammation.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Coronary Vessels; Fibrosis; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptor, PAR-1; Signal Transduction; Vascular Remodeling | 2017 |
Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathy.
Topics: Alanine Transaminase; Angiotensin II; Animals; Aorta; Blood Pressure; Carbazoles; Cardiomegaly; Cardiomyopathies; Carvedilol; Constriction; Cystatin C; Denervation; Fibrosis; Heart Rate; Kidney; Malondialdehyde; Natriuretic Peptide, Brain; Organ Specificity; Oxidative Stress; Peptide Fragments; Procollagen; Propanolamines; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta1; Vascular Remodeling | 2016 |
Caveolin-1 Deletion Prevents Hypertensive Vascular Remodeling Induced by Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Caveolin 1; Disease Models, Animal; Gene Deletion; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2017 |
Differential hypertensive protease expression in the thoracic versus abdominal aorta.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Cathepsin K; Cathepsin L; Cathepsins; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypertension; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; RNA, Messenger; Vascular Remodeling | 2017 |
Cellular Repressor of E1A-Stimulated Genes Is a Critical Determinant of Vascular Remodeling in Response to Angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Protein c-ets-1; Rats, Inbred Dahl; Recombinant Proteins; Repressor Proteins; RNA Interference; Signal Transduction; Sodium Chloride, Dietary; Time Factors; Transfection; Vascular Remodeling | 2017 |
Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bone Marrow Transplantation; Cell Movement; Disease Models, Animal; Fingolimod Hydrochloride; Genetic Predisposition to Disease; Hypertension; Inflammation Mediators; Lymph Nodes; Lysophospholipids; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; T-Lymphocytes; Time Factors; Vascular Remodeling | 2017 |
Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regulation; Hypertension; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Remodeling | 2017 |
Polydatin attenuates hypoxic pulmonary hypertension and reverses remodeling through protein kinase C mechanisms.
Topics: Angiotensin II; Animals; Endothelins; Glucosides; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Phorbol Esters; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Vascular Remodeling | 2012 |