angiotensin ii has been researched along with Innate Inflammatory Response in 612 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (1.96) | 18.7374 |
1990's | 9 (1.47) | 18.2507 |
2000's | 155 (25.33) | 29.6817 |
2010's | 300 (49.02) | 24.3611 |
2020's | 136 (22.22) | 2.80 |
Authors | Studies |
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Fang, H; Gao, F; Li, C; Wang, Y; Xue, K | 1 |
Bin, J; Cai, D; Chen, Y; Li, C; Liao, W; Liao, Y; Lin, Z; Ma, Y; Shi, X; Song, H; Sun, Y; Wei, G; Yang, Y; Zheng, H; Zhong, L | 1 |
Bandinelli, M; Boddi, M; Chiostri, M; Coppo, M; Modesti, PA; Poggesi, L | 1 |
Aonuma, K; Chikamori, T; Kosuge, H; Murakoshi, N; Nakamura, M; Oyane, A; Sakai, S; Sato, A; Shigekawa, H; Tajiri, K; Taninaka, A | 1 |
Guo, X; Kong, X; Miao, J; Sun, W; Tu, J; Weng, L; Wu, T; Wu, X; Xu, T; Yang, C; Zhang, D; Zhang, J; Zhao, K; Zhou, B | 1 |
Becares, M; Bermeo, H; Briones, AM; García-Redondo, AB; González-Amor, M; Guerra, S; Jorge, I; Martínez-González, J; Montezano, AC; Redondo, JM; Rios, FJ; Rodrigues-Díez, R; Rodríguez, C; Ruiz-Rodríguez, MJ; Salaices, M; Touyz, RM; Vázquez, J; Zalba, G | 1 |
Cai, X; Deng, L; Fan, G; Guo, R; Li, L; Liu, W; Ni, J; Xu, Q; Zhang, D; Zhao, Y | 1 |
Deng, HY; Dong, ZC; Han, X; He, ZY; Li, HH; Zhang, YL | 1 |
Kuruppu, S; Rajapakse, NW; Tran, S | 1 |
Bai, WW; Gao, CH; Guo, BX; Jiang, F; Li, C; Liu, KY; Qin, WD; Wang, H; Zhang, MX | 1 |
Gurusamy, N; Sukumaran, V; Venkatesh, S; Yalcin, HC | 1 |
Chen, X; Liu, X; Lou, J; Tang, L; Weng, Y; Xu, C | 1 |
Cao, Y; Chen, C; Chen, Y; Deng, K; Deng, X; Han, X; He, C; He, J; Jiang, W; Lei, A; Li, X; Liu, G; Lu, L; Tan, M; Wang, Y; Wu, P; Xiao, Q; Xu, H; Yang, Q; Yao, Z; Zhang, L; Zhou, J; Zhou, P | 1 |
Bi, W; Gao, X; Huo, YB; Nie, Q; Peng, Q | 1 |
Bajpai, G; Bredemeyer, A; Feng, G; Förster, I; Koenig, A; Kreisel, D; Lai, L; Lavine, KJ; Leuschner, F; Lokshina, I; Ma, P | 1 |
Chen, H; Qiao, H; Wei, F; Zhao, Q | 1 |
Abderrahim, N; Adriani, W; Ahmed, F; Algarra, M; Amor, HB; Andreasi, V; Bailey, RL; Bettinardi, V; Bezzi, C; Bithe, SA; Boumnijel, I; Burr, SE; Cadmus, P; Calcaprina, B; Canevari, C; Catalfamo, B; Chen, J; Chen, X; Chen, Y; Clements, WH; Cornick, J; Cotton, SJ; De Cobelli, F; Djellabi, R; Falconi, M; Ghezzo, S; Gianolli, L; Guarnaccia, A; Guo, X; Hart, JD; Hasan, MM; Head-Gordon, M; Iwasaki, Y; Kalua, K; Kong, X; Laviola, G; Li, L; Li, M; Liu, M; Mao, Y; Mapelli, P; Meleke, H; Messina, A; Miller, WH; Muffatti, F; Neher, B; Palumbo, D; Partelli, S; Peláez, D; Pepe, M; Picchio, M; Presotto, L; Ranville, J; Samanes Gajate, AM; Samikwa, L; Schiavo Lena, M; Scifo, P; Shu, H; Soto, J; Sun, W; Talbot, JJ; Tu, J; Vaquer, F; Weng, L; Wu, J; Xu, T; Zhang, D; Zhao, B; Zhao, K; Zhao, Y | 1 |
Chen, Y; Dong, Z; Guo, Y; Jin, H; Li, X; Liu, X; Liu, Y; Song, J; Wang, N; Xu, Y; Zhang, M; Zhang, Z; Zhong, J | 1 |
Chen, YL; Cheng, HC; Hsu, CY; Lee, CW; Lee, IT; Lin, WN; Vo, QC; Vo, TTT | 1 |
Stanley, JC | 1 |
Ferrara, F; La Porta, R; Trama, U; Troiano, V; Vitiello, A | 1 |
Dai, S; Hong, X; Huang, W; Liang, X; Lin, J; Lin, S; Wang, W; Ye, B | 1 |
Hua, D; Li, P; Li, Y; Mao, Y; Wu, X; Yong, Y; Zhao, K; Zhou, Z | 1 |
Du, J; Kong, L; Li, Y; Yang, C; Yao, R; Zhao, G | 1 |
Gan, L; Hu, X; Li, H; Li, X; Lu, Y; Meng, T; Peng, L; Tang, R; Wang, W; Xiao, C; Xiao, P; Zhou, Q | 1 |
Davidge, ST; Fan, H; Liao, W; Wu, J | 1 |
Enggaard, C; Hansen, PBL; Jensen, BL; Palarasah, Y; Stubbe, J; Svenningsen, P; Thangaraj, SS | 1 |
D'Addiaro, C; De Miguel, C; Gupte, R; Gupte, SA; Matsumura, S; Miano, JM; Slivano, OJ; Stier, C | 1 |
Han, X; Li, G; Liang, G; Liang, S; Long, X; Luo, W; Sun, J; Wang, M; Yu, T; Zhang, Y | 1 |
Chattipakorn, N; Chen, R; Chen, Y; Dai, C; Huang, W; Liang, G; Luo, W; Shen, S; Wang, J; Wang, Z | 1 |
Abd El-Aal, SA; Al Khabbaz, HJ; Arab, HH; Arafa, EA; Ashour, AM; El-Sheikh, AAK; Kabel, AM; Mahmoud, AM | 1 |
Jiang, X; Liu, W; Meng, L; Tian, Y; Wang, H; Xin, Y; Zhang, Q | 1 |
Chi, C; Fu, H; Fu, JT; Ji, QX; Li, DJ; Li, YH; Li, ZC; Liu, J; Shen, FM; Shen, QR; Sun, DY; Wang, P; Wang, XJ; Wu, WB; Zeng, FY; Zhang, GY; Zhang, JB; Zhang, PP; Zhou, CC | 1 |
Abu Bakar, ZH; Hamezah, HS; Matsuzaki Tada, A; Pahrudin Arrozi, A; Tooyama, I; Yanagisawa, D | 1 |
Li, G; Liang, G; Liang, S; Luo, W; Sun, J; Wang, M; Yu, T; Zou, C | 1 |
Al Makki, R; Ashley, NT; Eads, KN; Ensminger, DC; Wheeler, ND | 1 |
Asgharzadeh, F; Askarnia-Faal, MM; Avan, A; Daghiani, M; Hassanian, SM; Khazaei, M; Naimi, H; Nazari, SE; Sayyed-Hosseinian, SH; Vahedi, E | 1 |
Chen, L; Lei, L; Pan, Y; Wang, T; Zheng, Z; Zhou, Y | 1 |
Chang, L; Chang, Z; Chen, YE; Garcia-Barrio, MT; Guo, Y; Liang, W; Lin, JD; Liu, H; Liu, Y; Lu, H; Rom, O; Wang, H; Yang, B; Zhang, J; Zhao, G; Zhao, Y; Zhu, T | 1 |
Chen, D; Chen, K; Chu, J; Gao, H; Jia, P; Lin, S; Lin, W; Long, L; Peng, J; Shen, A; Wang, T; Zhu, Y; Zhu, Z | 1 |
Hu, X; Huang, W; Khan, ZA; Liang, G; Lin, K; Luo, W; Su, L; Wang, Y; Wu, G; Yang, N; Zhou, H | 1 |
Crorkin, P; Ferreri, NR; Hao, S | 1 |
Barthelemy, J; Bogard, G; Briand, F; Chabrat, A; Deruyter, L; Domenig, O; Heumel, S; Hoffmann, E; Infanti, F; Machelart, A; Nogueiras, R; Pinet, F; Prévot, V; Richard, V; Robil, C; Sencio, V; Sulpice, T; Trottein, F; Wolowczuk, I | 1 |
Chan, CCMY; Gan, PXL; Heng, CKM; Liao, W; Mei, D; Tran, QTN; Wong, WSF | 1 |
Bai, C; Chen, J; Hui, R; Li, H; Lin, Y; Liu, J; Ping, J; Song, L; Su, M; Sun, Y; Wen, H; Xiao, N; Xu, H; Zhang, M; Zhang, Y | 1 |
Liang, G; Luo, W; Shan, P; Wang, M; Wang, Y; Wu, G; Xu, D; Yang, N; Zou, C | 1 |
Bottermann, K; Deenen, R; Fischer, JW; Gödecke, A; Grandoch, M; Harris, TE; Hemmers, A; Herebian, D; Kalfhues, L; Köhrer, K; Leitner, LM; Nederlof, R; Nemmer, J; Oenarto, V; Petzsch, P; Pfeffer, M; Raje, V; Reichert, AS; Stegbauer, J; Zabri, H | 1 |
Chen, D; Gao, S; Ge, S; Luo, J; Niu, K; Ren, M; Shao, Y; Wang, X; Wu, Q; Xiao, Q; Yang, M; Yang, Z; Zhang, C; Zhou, X | 1 |
Aono, J; Hamaguchi, M; Ikeda, S; Inoue, K; Kakino, A; Kurata, M; Nakao, Y; Sakaue, T; Sawamura, T; Suehiro, C; Suzuki, J; Takahashi, K; Yamaguchi, O | 1 |
Caroccia, B; Hanssen, NMJ; Piazza, M; Rossi, GP; Schalkwijk, CG; Scheijen, JLJM; Seccia, TM; Stehouwer, CDA; Vd Waarenburg, M | 1 |
Labandeira, CM; Labandeira-Garcia, JL; Lanciego, JL; Pedrosa, MA; Quijano, A; Rodriguez-Perez, AI; Sanchez-Andrade, M; Suarez-Quintanilla, JA; Valenzuela, R | 1 |
Domenig, O; Hartl, L; Hecking, M; Jachs, M; Mandorfer, M; Marculescu, R; Paternostro, R; Poglitsch, M; Reiberger, T; Reindl-Schwaighofer, R; Rumpf, B; Simbrunner, B; Trauner, M | 1 |
Cai, D; Chen, SY; Murashita, T; Que, X; Sun, C | 1 |
Barthuber, C; Boege, F; Dechend, R; Heidecke, H; Karschnia, M; Kaufmann, S; Kelm, M; Roden, M; Scheiber, D; Szendrödi, J; Westenfeld, R; Zweck, E | 1 |
Pan, Y; Zha, Z; Zheng, Z; Zhou, M | 1 |
Chaturvedi, S; Gupta, S; Hanif, K; Mishra, A; Shukla, S; Singh, J; Singh, S; Tiwari, P; Tiwari, V; Wahajuddin, M | 1 |
Fernandez-Llimos, F; Fresco, P; Gonçalves, J; Santos, CD | 1 |
Al-Salam, S; Ali, BH; Beegam, S; Elzaki, O; Nemmar, A; Zaaba, NE | 1 |
Almendra-Pegueros, R; Consegal-Pérez, M; Galán, M; Jiménez-Altayó, F; Julve, J; Kassan, M; Martínez-González, J; Navas-Madroñal, M; Pérez, B; Puertas-Umbert, L; Rodriguez, C | 1 |
Guo, R; Li, Y; Tao, L; Xu, Y | 1 |
Anand, P; Bhati, P; Deepak, KK; Hussain, ME; Masood, S | 1 |
Bai, H; Ben, J; Chen, Q; Huang, J; Ji, R; Jia, Y; Jiang, B; Jiang, Y; Li, X; Wang, J; Wang, S; Yang, Q; Zhang, H; Zhou, Z; Zhu, X | 1 |
Azemi, AK; Mokhtar, SS; Rasool, AHG; Wee, CL; Yaacob, NS; Yahaya, S | 1 |
Chen, HZ; Chen, YN; Ding, YN; Hao, DL; Liu, DP; Lv, SJ; Sun, LH; Tang, X; Wang, HP; Wang, HY; Wang, L; Wang, TT; Wang, XM; Wei, ZY; Xu, HS; Yao, F; Zhang, ZQ; Zhao, X; Zhou, Z | 1 |
Carletti, R; Castoldi, G; Colzani, M; di Gioia, CRT; Ippolito, S; Pelucchi, S; Perseghin, G; Zatti, G; Zerbini, G | 1 |
Benndorf, RA; Dubourg, V; Gekle, M; Schreier, B; Schwerdt, G | 1 |
Liu, J; Liu, S; Pan, W; Peng, S; Qin, JJ; Wan, J; Wang, M; Wei, C; Xu, S; Xu, Y; Ye, J; Yin, Z; Zhang, J; Zhao, M; Zheng, Z | 1 |
Becker, K; Bouvain, P; Flögel, U; Grandoch, M; Ibrahim, F; Massold, T; Niemann, V; Schrader, J; Steckel, B; Stegbauer, J; Temme, S | 1 |
Alvarado-Ojeda, ZA; Arrellín-Rosas, G; Baez Reyes, JC; Castro-Martínez, G; Cruz-Muñoz, ME; Fragoso, G; Jimenez-Ferrer, JE; Méndez-Martínez, M; Salgado, GR; Trejo-Moreno, C; Zamilpa, A | 1 |
Cao, M; Chen, X; Ding, J; Liao, M; Liao, Y; Qiu, Z; Wang, M; Wang, Y; Wu, H; Yan, X; Zhang, H; Zheng, J; Zhou, Y | 1 |
Li, X; Li, Y; Lou, A; Su, L; Tong, H; Zhang, M; Zhu, X | 1 |
Das, A; Fukai, T; Sudhahar, V; Ushio-Fukai, M | 1 |
An, S; Cho, S; Jeong, J; Lee, J; Lee, M; Lim, J; Lim, S; Park, S; Seo, M; Yoon, N | 1 |
Atala, A | 1 |
Chen, HQ; Kong, H; Xue, HX; Yin, YY; Yu, YG; Zhou, JW | 1 |
Huang, H; Liu, YM; Lv, YG; Wu, RD; Xu, JQ; Zhu, W | 1 |
Bishop, E; Bordas, M; Chowdhury, SR; Cossette, SM; Gupta, A; Harmann, LM; Kumar, SN; Lu, Q; Pan, AY; Ramchandran, R; Simpson, PM; Sonin, DL; Spearman, AD; Strande, JL; Thirugnanam, K; Zou, MH | 1 |
Ren, Q; Ren, W; Ruan, Y; Wang, J; Wang, Z; Wu, Z; Yu, A | 1 |
Arslanbaeva, L; Auwerx, J; Billings, FT; Dikalov, SI; Dikalova, AE; Harrison, DG; Lopez, MG; Pandey, A; Sidorova, T; Verdin, E; Xiao, L | 1 |
Buitrago, DM; Castillo, DM; Chacon-Quintero, Y; Lafaurie, GI; Morantes, SJ; Viafara-García, SM | 1 |
Aboulkhair, AG; El-Sayed, LA; Mehesen, MN; Omar, AI; Osama, E; Rashed, LA; Shams Eldeen, AM | 1 |
Alonso, J; Ballester-Servera, C; Cañes, L; Galán, M; Herraiz-Martínez, A; Hove-Madsen, L; Martí-Pàmies, I; Martínez-González, J; Muniesa, P; Nistal, JF; Osada, J; Rodríguez, C | 1 |
Akhondzadeh, F; Astani, A; Najjari, R; Ranjbar, AM; Rezvani, ME; Safari, F; Samadi, M; Zare, F | 1 |
Nataf, S | 1 |
Beltz, TG; Guo, F; Hurley, SW; Johnson, AK; Xue, B | 1 |
Chen, Q; Du, J; Huang, Y; Jin, H; Kong, W; Li, K; Tang, C; Yu, X; Zhang, L; Zhu, Z | 1 |
Jiang, SJ; Liang, LW; Lu, P; Shi, Z; Sun, YY; Xu, AL | 1 |
Chen, W; Wang, Y; Zhang, Y | 1 |
Dutta, SR; Gonzalez, FJ; Malik, KU; Singh, P; Song, CY | 1 |
Su, GH; Sun, ML; Sun, YP; Yang, JM | 1 |
Bao, LY; Cai, QY; Chen, YQ; Chu, JF; Jia, BB; Lin, S; Peng, J; Wang, H; Ye, RZ; Zhang, L | 1 |
Aoki, H; Fukumoto, Y; Furusho, A; Hashimoto, Y; Hayashi, M; Hirakata, S; Ito, S; Kuwahara, K; Majima, R; Nakao, E; Nishida, N; Nishihara, M; Ohno-Urabe, S | 1 |
Ajayi, OI; Bafor, EE; Ebeigbe, AB; Nwokocha, CR | 1 |
Li, L; Li, Y; Ma, W; Pan, S; Shi, X; Tian, Y; Wang, H; Xu, C | 1 |
Breyer, RM; Fujita, T; Goda, M; Hiromi, T; Ichikawa, Y; Ishikawa, Y; Ishiwata, R; Kurotaki, D; Mamun, A; Masuda, M; Minami, T; Nishihara, H; Suzuki, S; Takeuchi, I; Tamura, T; Uchida, K; Umemura, M; Yasuda, S; Yokoyama, U | 1 |
Chen, L; FitzGerald, GA; Jiang, T; Monslow, J; Puré, E; Tang, SY; Todd, L; Yang, G; Zhang, J | 1 |
Alves-Lopes, R; Camargo, LL; Montezano, AC; Neves, KB; Rios, FJ; Touyz, RM | 1 |
Formanowicz, D; Formanowicz, P; Radom, M; Rybarczyk, A | 1 |
Abbas, MM; Bensmail, H; Gunaratne, P; Kalupahana, NS; Menikdiwela, KR; Moustaid-Moussa, N; Palat, A; Ramalingam, L; Scoggin, S | 1 |
Mao, XY; Peng, W; Wu, ML; Yin, XX; Zheng, XR | 1 |
Akagi, T; Fujita, S; Kawahara, K; Mito, T; Morita, Y; Mukai, T; Tsuji, S; Uchida, HA | 1 |
Chávez-Alderete, J; Loza-Mejía, MA; Maldonado, V | 1 |
Bin, J; Feng, X; He, X; Lai, Y; Liao, W; Liao, Y; Song, H; Wei, G; Xu, T; Yang, Y; Zheng, H; Zhong, L | 1 |
Cao, W; Li, Y; Qian, Y; Wang, J; Zhao, P; Zhu, H | 1 |
Grochot-Przęczek, A; Hajduk, K; Józkowicz, A; Klóska, D; Kopacz, A; Neumayer, C; Piechota-Polanczyk, A; Werner, E | 1 |
Brangsch, J; Buchholz, R; Hamm, B; Karst, U; Klopfleisch, R; Kosch, O; Makowski, MR; Mangarova, DB; Mohtashamdolatshahi, A; Paysen, H; Schnorr, J; Taupitz, M; Wiekhorst, F | 1 |
Chen, Z; He, X; Liu, X; Lu, Y; Miao, R; Wang, J | 1 |
Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; 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Browatzki, M; Kranzhöfer, R; Kübler, W; Schmidt, J | 1 |
Adam, A; Blais, C; Leclair, P; Molinaro, G | 1 |
Egashira, K; Katoh, M; Koyanagi, M; Matsushima, K; Shimokawa, H; Takeshita, A; Takeya, M; Tomita, H; Usui, M; Yoshimura, T | 1 |
Breu, V; Dechend, R; Fiebeler, A; Ganten, D; Gulba, D; Haller, H; Luft, FC; Luther, T; Mackman, N; Mervaala, EM; Müller, DN; Park, JK; Schmidt, F; Schneider, W; Theuer, J | 1 |
Breu, V; Dechend, R; Ganten, D; Genersch, E; Haller, H; Löffler, BM; Luft, FC; Mervaala, EM; Muller, DN; Park, JK; Schmidt, F; Schneider, W | 1 |
Luft, FC | 3 |
Kulkarni, SK; Raghavendra, V | 1 |
Dzau, VJ | 1 |
Egido, J; Lorenzo, O; Ruiz-Ortega, M; Rupérez, M; Suzuki, Y | 1 |
Bischoff, H; Dechend, R; Dietz, R; Fiebler, A; Haller, H; Lindschau, C; Luft, FC; Müller, D; Park, JK | 1 |
Akishita, M; Chen, R; de Gasparo, M; Horiuchi, M; Iwai, M; Li, Z; Nakagami, H; Suzuki, J; Wu, L | 1 |
Patston, PA; Ramaha, A | 1 |
Fujihara, CK; Noronha, IL; Zatz, R | 1 |
Böger, RH; Drexler, H; Forssmann, WG; Krämer, C; Luchtefeld, M; Schieffer, B; Schmidt, B; Sunkomat, J; Tsikas, D; Walden, M; Witte, J | 1 |
Miyazaki, M; Takai, S | 1 |
Amiri, F; Cohn, JS; Diep, QN; El Mabrouk, M; Endemann, D; Neves, MF; Schiffrin, EL; Virdis, A | 1 |
Kagiyama, S; Phillips, MI | 1 |
Lewis, GP | 1 |
Novak, D; Weber, J | 1 |
Bekemeier, H; Hänsel, F | 1 |
Brady, FO; Funk, AE; Garrett, SH; Helvig, BS | 1 |
Kassab, J; Weinstock, JV | 1 |
Goodfriend, TL; McGuire, JS; Webster, ME | 1 |
Olsen, F | 3 |
Singer, B | 1 |
Huber, G; Jaques, R; Meier, R; Neipp, L; Rossi, A; Schär, B | 1 |
101 review(s) available for angiotensin ii and Innate Inflammatory Response
Article | Year |
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Chronic Renin-Angiotensin System Activation Induced Neuroinflammation: Common Mechanisms Underlying Hypertension and Dementia?
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Brain; Cytokines; Dementia, Vascular; Humans; Hypertension; Inflammation; Peptide Fragments; Renin-Angiotensin System | 2022 |
Understanding diabetes-induced cardiomyopathy from the perspective of renin angiotensin aldosterone system.
Topics: Angiotensin II; Animals; Autophagy; Diabetic Cardiomyopathies; Humans; Inflammation; Obesity; Oxidative Stress; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin-Angiotensin System | 2022 |
Responses to Ang II (Angiotensin II), Salt Intake, and Lipopolysaccharide Reveal the Diverse Actions of TNF-α (Tumor Necrosis Factor-α) on Blood Pressure and Renal Function.
Topics: Angiotensin II; Blood Pressure; Cytokines; Humans; Inflammation; Kidney; Lipopolysaccharides; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha | 2022 |
Potential use of renin-angiotensin-aldosterone system inhibitors to reduce COVID-19 severity.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Humans; Inflammation; Peptidyl-Dipeptidase A; Renin-Angiotensin System; SARS-CoV-2 | 2023 |
The role of EGFR in vascular AT1R signaling: From cellular mechanisms to systemic relevance.
Topics: Angiotensin II; Cardiovascular Diseases; ErbB Receptors; Humans; Inflammation; Receptor, Angiotensin, Type 1; Tyrosine | 2023 |
The Malaria-High Blood Pressure Hypothesis: Revisited.
Topics: Angiotensin II; Calcium Signaling; Cell Survival; Cytokines; Developing Countries; Endothelium; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Inflammation; Malaria; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neurotransmitter Agents; Nitric Oxide; Peptidyl-Dipeptidase A; Pre-Eclampsia; Pregnancy; Renin-Angiotensin System | 2020 |
Oxidative Stress: A Unifying Paradigm in Hypertension.
Topics: Aldosterone; Angiotensin II; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Inflammation; Intercellular Signaling Peptides and Proteins; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sex Factors; Signal Transduction; Vascular Remodeling; Vascular Stiffness; Vasoconstriction | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Pathophysiology of Hypertension: The Mosaic Theory and Beyond.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Vessels; Body Fluids; Central Nervous System; Humans; Hypertension; Inflammation; Kidney; Microbiota; Reactive Oxygen Species; Risk Factors; Sodium Chloride; Vasoconstrictor Agents | 2021 |
Renin-angiotensin system and inflammation update.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autoimmunity; Blood Pressure; Gene Expression Regulation; Humans; Inflammation; Kidney; Klotho Proteins; Peptide Fragments; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; T-Lymphocytes; Water-Electrolyte Balance | 2021 |
Thromboplasminflammation in COVID-19 Coagulopathy: Three Viewpoints for Diagnostic and Therapeutic Strategies.
Topics: Angiotensin II; Animals; Blood Coagulation Disorders; COVID-19; Cytokines; Factor XIIa; Humans; Inflammation; Inflammation Mediators; SARS-CoV-2 | 2021 |
The interplay between Angiotensin II, TLR4 and hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; Brain; Humans; Hypertension; Immunity, Innate; Inflammation; Kidney; Renin-Angiotensin System; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Potential of angiotensin II receptor blockers in the treatment of diabetic retinopathy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Diabetic Retinopathy; Humans; Inflammation; Neovascularization, Pathologic; Oxidative Stress; Renin-Angiotensin System | 2017 |
Renin angiotensin system in liver diseases: Friend or foe?
Topics: Angiotensin II; Animals; Cell Proliferation; Fibrosis; Hemodynamics; Hepatorenal Syndrome; Humans; Inflammation; Liver; Liver Cirrhosis; Liver Diseases; Mice; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2017 |
Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies.
Topics: Acute Disease; Angiotensin II; Chronic Disease; Homeostasis; Humans; Inflammation; Renin; Renin-Angiotensin System | 2017 |
Angiotensin-converting enzyme 2 and renal disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus; Fibrosis; Humans; Inflammation; Kidney; Kidney Diseases; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2018 |
Immunologic and endocrine functions of adipose tissue: implications for kidney disease.
Topics: Adipokines; Adiponectin; Adipose Tissue; AMP-Activated Protein Kinases; Angiotensin II; Angiotensinogen; Ceramidases; Diabetes Mellitus, Type 2; Humans; Inflammation; Kidney Diseases; Leptin; Macrophages; Obesity; Receptors, Adiponectin; Signal Transduction | 2018 |
Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.
Topics: Adipocytes; Angiotensin II; Animals; Blood Vessels; Brain; Heart Diseases; Humans; Inflammation; Kidney; Kidney Diseases; Receptors, Angiotensin; Signal Transduction | 2018 |
Chronic heart failure: a disease of the brain.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Baroreflex; Brain; Cardiomegaly; Chronic Disease; Heart; Heart Failure; Humans; Inflammation; Natriuretic Peptide, Brain; Neuroimmunomodulation; Norepinephrine; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Renin-Angiotensin System; Sympathetic Nervous System; Vagus Nerve Stimulation | 2019 |
Inflammatory biomarkers for predicting cardiovascular disease.
Topics: Angiotensin II; Antioxidants; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cell Adhesion Molecules; Cytokines; Glycation End Products, Advanced; Humans; Inflammation; Oxidative Stress; Prognosis; Risk Factors | 2013 |
The spleen in local and systemic regulation of immunity.
Topics: Adaptive Immunity; Angiotensin II; Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Lineage; Drug Delivery Systems; Hematopoietic Stem Cells; Humans; Immune Tolerance; Immunity, Innate; Immunotherapy, Adoptive; Inflammation; Lymphocyte Subsets; Mice; Models, Immunological; Neoplasms; Phagocytes; Species Specificity; Spleen | 2013 |
Proinflammation: the key to arterial aging.
Topics: Aged; Aging; Angiotensin II; Animals; Antigens, Surface; Arteries; Arteritis; Atherosclerosis; Calpain; Chemokine CCL2; Endothelin-1; Humans; Hypertension; Inflammation; Inflammation Mediators; Matrix Metalloproteinase 2; Middle Aged; Milk Proteins; Muscle, Smooth, Vascular; Nitric Oxide; Reactive Oxygen Species; Receptors, CCR2; Transforming Growth Factor beta1 | 2014 |
Depression and cardiovascular disease in women: is there a common immunological basis? A theoretical synthesis.
Topics: Angiotensin II; Cardiovascular Diseases; Cytokines; Depression; Female; Humans; Hypothalamo-Hypophyseal System; Inflammation; Male; Pituitary-Adrenal System; Pre-Eclampsia; Pregnancy; Serotonin; Sex Factors; T-Lymphocytes, Regulatory | 2014 |
[Renin-aldosterone and bone metabolism].
Topics: Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Bone and Bones; Calcium; Cardiovascular Diseases; Drug Discovery; Humans; Hypertension; Inflammation; Molecular Targeted Therapy; Osteoporosis; Oxidative Stress; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Mineralocorticoid; Renin; Renin-Angiotensin System | 2014 |
ACE and ACE2 in inflammation: a tale of two enzymes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Inflammation; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2014 |
Angiotensin II in inflammation, immunity and rheumatoid arthritis.
Topics: Angiotensin II; Animals; Arthritis, Rheumatoid; Humans; Inflammation; Lupus Erythematosus, Systemic; Multiple Sclerosis | 2015 |
The pathophysiology of otosclerosis: Review of current research.
Topics: Angiotensin II; Animals; Autoimmunity; Collagen; Genetic Predisposition to Disease; Hearing Loss; HLA Antigens; Humans; Inflammation; Measles virus; Otosclerosis; Oxidative Stress; Parathyroid Hormone; Reactive Oxygen Species; Stapes; Transforming Growth Factor beta | 2015 |
Atherosclerosis and aortic aneurysm - is inflammation a common denominator?
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Cytokines; Diet, Western; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Risk Factors; Sedentary Behavior; Smoking | 2016 |
Redox regulation of cardiovascular inflammation - Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species.
Topics: Angiotensin II; Cardiovascular Diseases; Cardiovascular System; Endothelial Cells; Extracellular Traps; Gene Expression Regulation; Humans; Inflammation; Mitochondria; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction | 2017 |
Angiotensin Peptides as AT2 Receptor Agonists.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Gene Expression; Humans; Hypertension; Inflammation; Kinetics; Peptides; Peptidomimetics; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Sulfonamides; Thiophenes | 2017 |
Newly developed angiotensin II-infused experimental models in vascular biology.
Topics: Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Blood Vessels; Female; Humans; Hypertension; Inflammation; Mice; Mice, Transgenic; Models, Biological; Neovascularization, Pathologic; Neovascularization, Physiologic; Postmenopause; Pre-Eclampsia; Pregnancy; Vascular Diseases | 2008 |
Iron in arterial plaque: modifiable risk factor for atherosclerosis.
Topics: Angiotensin II; Animals; Antimicrobial Cationic Peptides; Atherosclerosis; Carotid Arteries; Ferritins; Haptoglobins; Heme Oxygenase-1; Hemochromatosis; Hepcidins; Humans; Inflammation; Interleukin-6; Iron; Macrophages; Polymorphism, Genetic; Risk Factors | 2009 |
Myocardial repair/remodelling following infarction: roles of local factors.
Topics: Angiotensin II; Animals; Cell Death; Fibrosis; Heart Failure; Humans; Inflammation; Myocardial Infarction; Myocardium; Oxidative Stress; Prognosis; Reactive Oxygen Species; Signal Transduction; Ventricular Remodeling | 2009 |
Oxidative stress and hypertension.
Topics: Angiotensin II; Blood Vessels; Central Nervous System; Humans; Hypertension; Inflammation; Kidney; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2009 |
[The renin-angiotensin system].
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Arteries; Humans; Hypertension; Inflammation; Mineralocorticoid Receptor Antagonists; Models, Cardiovascular; Renin; Renin-Angiotensin System | 2009 |
Renal infiltration of immunocompetent cells: cause and effect of sodium-sensitive hypertension.
Topics: Adult; Angiotensin II; Animals; Autoimmunity; Disease Models, Animal; Heat-Shock Proteins; Humans; Hypertension; Immunocompetence; Inflammation; Kidney; Middle Aged; Nephritis; Oxidative Stress; Rats; Sodium; Sodium, Dietary | 2010 |
The role of inflammatory and fibrogenic pathways in heart failure associated with aging.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Angiotensin II; Fibroblasts; Fibrosis; Heart Failure, Diastolic; Humans; Inflammation; Muscle Cells; Phagocytes; Reactive Oxygen Species; Risk Factors; Transforming Growth Factor beta; United States; Ventricular Remodeling | 2010 |
STAT3 and cardiac remodeling.
Topics: Aging; Angiotensin II; Cardiomyopathy, Dilated; Extracellular Matrix; Humans; Inflammation; Mitochondria; Myocardium; Myocytes, Cardiac; Signal Transduction; STAT3 Transcription Factor; Ventricular Remodeling | 2011 |
Midkine regulation of the renin-angiotensin system.
Topics: Acetylcholinesterase; Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Central Nervous System; Cytokines; Fibroblast Growth Factors; Humans; Hypertension; Inflammation; Kidney Failure, Chronic; Lung; Mice; Midkine; Receptors, Fibroblast Growth Factor; Renin; Renin-Angiotensin System; Risk Factors | 2010 |
Oxidative stress and hypertension: current concepts.
Topics: Angiotensin II; Animals; Antioxidants; Cytokines; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hypertension; Inflammation; NADP; Nitric Oxide Synthase; Oxidative Stress; Reactive Oxygen Species; Risk Factors; Signal Transduction; Superoxides; Xanthine Oxidase | 2010 |
Hypertension management and microvascular insulin resistance in diabetes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Diabetes Mellitus, Type 2; Humans; Hypertension; Inflammation; Insulin Resistance; Microcirculation; Microvessels; Nitric Oxide Synthase Type III; Oxidative Stress; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction | 2010 |
Angiotensin II revisited: new roles in inflammation, immunology and aging.
Topics: Aging; Angiotensin II; Autoimmunity; Humans; Inflammation; Oxidative Stress; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 2010 |
The central nervous system and inflammation in hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; Brain; Humans; Hypertension; Immune System; Inflammation; Lymphocyte Activation; Renin-Angiotensin System; T-Lymphocytes | 2011 |
[Critical role of renin-angiotensin system in the pathogenesis of atherosclerosis].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atherosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Disease Progression; Endothelium, Vascular; Humans; Inflammation; Reactive Oxygen Species; Renin-Angiotensin System | 2011 |
[The effect of ARB on prevention of atherosclerosis].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Humans; Inflammation; Myocardial Infarction; Oxidative Stress; Randomized Controlled Trials as Topic; Risk Factors; Stroke | 2011 |
[Angiotensin II-induced monocyte/macrophage inflammatory effects and drug intervention].
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Humans; Inflammation; Macrophages; Monocytes | 2011 |
[Role of chronic inflammation in the pathogenesis of atherosclerosis].
Topics: Adipokines; Adipose Tissue; Angiotensin II; Animals; Atherosclerosis; Chronic Disease; Coronary Vessels; Cytokines; Humans; Inflammation; Inflammation Mediators; Life Style; Macrophages; Neovascularization, Pathologic; Plaque, Atherosclerotic; Vascular Endothelial Growth Factor A | 2011 |
Angiotensin II induces inflammation leading to cardiac remodeling.
Topics: Angiotensin II; Animals; Chemokines; Cytokines; Humans; Inflammation; Models, Cardiovascular; Myofibroblasts; Renin-Angiotensin System; Signal Transduction; Ventricular Remodeling | 2012 |
Inflammation in hypertension: current therapeutic approaches.
Topics: Adipose Tissue; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Cell Adhesion Molecules; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Inflammation; Inflammation Mediators; NF-kappa B; Reactive Oxygen Species | 2011 |
Role of inflammation in the pathogenesis of arterial stiffness.
Topics: Angiotensin II; Humans; Inflammation; Matrix Metalloproteinases; Vascular Stiffness | 2012 |
Angiotensin II, NADPH oxidase, and redox signaling in the vasculature.
Topics: Angiotensin II; Animals; Humans; Inflammation; Muscle, Smooth, Vascular; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2013 |
Immune mechanisms in angiotensin II-induced target-organ damage.
Topics: Adaptive Immunity; Angiotensin II; Animals; Autoimmunity; Blood Vessels; Brain; Cardiovascular Diseases; Complement System Proteins; Humans; Immunity, Innate; Inflammation; Kidney; Lymphocytes; Myocardium; NF-kappa B; Renin; Renin-Angiotensin System | 2012 |
Angiotensin II AT(1) receptor blockers as treatments for inflammatory brain disorders.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Brain; Brain Diseases; Brain Injuries; Brain Ischemia; Humans; Inflammation; Mood Disorders; Neurodegenerative Diseases; Neuroprotective Agents; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Factors; Stress, Physiological; Stroke | 2012 |
General pathophysiology of macular edema.
Topics: Angiotensin II; Blood-Retinal Barrier; Humans; Inflammation; Ischemia; Macular Edema; Prostaglandins; Vascular Endothelial Growth Factor A | 2011 |
Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy.
Topics: Angiotensin II; Animals; Diabetic Retinopathy; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Infant, Newborn; Infant, Premature; Inflammation; Membrane Glycoproteins; Models, Animal; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Pathologic; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Retina; Retinopathy of Prematurity | 2013 |
Vascular inflammation and the renin-angiotensin system.
Topics: Acute-Phase Proteins; Angiotensin II; Animals; Arteriosclerosis; Cholesterol, LDL; Endothelium, Vascular; Feedback, Physiological; Humans; Inflammation; Interleukin-6; Liver; Macrophages; Monocytes; Oxidation-Reduction; Reactive Oxygen Species; Renin-Angiotensin System; Signal Transduction | 2002 |
Mechanisms of progressive renal disease: role of angiotensin II, cyclooxygenase products and nitric oxide.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Glomerular Mesangium; Humans; Inflammation; Kidney Diseases; Kidney Glomerulus; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Renin | 2002 |
The role of angiotensin II in regulating vascular structural and functional changes in hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Arteries; Cell Division; Fibrosis; Humans; Hypertension; Inflammation; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Oxidation-Reduction; Protein Serine-Threonine Kinases; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vascular Resistance; Vasomotor System | 2003 |
Inflammation and angiotensin II.
Topics: Angiotensin II; Animals; Capillary Permeability; Cell Adhesion; Chemokines; Endothelial Growth Factors; Endothelium, Vascular; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Lymphokines; Neutrophil Infiltration; Peptidyl-Dipeptidase A; Prostaglandins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Renin-angiotensin system and atherothrombotic disease: from genes to treatment.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Clinical Trials as Topic; Endothelium, Vascular; Growth Substances; Humans; Inflammation; Lipoproteins, LDL; Oxidative Stress; Renin-Angiotensin System; Risk Factors; Signal Transduction | 2003 |
Inflammation in uremic patients: what is the link?
Topics: Angiotensin II; Antioxidants; Arteriosclerosis; Biomarkers; Cholesterol, LDL; Humans; Inflammation; Oxidative Stress; Renal Dialysis; Risk Factors; Uremia | 2003 |
Multiple actions of angiotensin II in hypertension: benefits of AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Fibrinolysis; Humans; Hypertension; Inflammation; Inflammation Mediators; Oxidative Stress; Reactive Oxygen Species; Tetrazoles | 2003 |
Modulation of the inflammatory response in cardiovascular disease.
Topics: Angiotensin II; Animals; Blood Platelets; Cardiovascular Diseases; CD40 Antigens; CD40 Ligand; Cell Adhesion Molecules; Disease Progression; Endothelium, Vascular; Humans; Inflammation; Integrins; Models, Animal; Oxidative Stress; Renin-Angiotensin System; Risk Factors; Thrombophilia | 2004 |
Angiotensin in atherosclerosis.
Topics: Angiotensin II; Arteriosclerosis; Diabetes Mellitus; Disease Progression; Estrogens; Humans; Hyperlipidemias; Hypertension; Inflammation; Insulin Resistance; Risk Factors | 2004 |
[Renin-angiotensin system and vascular remodelling].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Arteriosclerosis; Blood Pressure; Blood Vessels; Fibrosis; Humans; Hypertension, Renovascular; Hypertrophy; Inflammation; Models, Biological; NADPH Oxidases; Reactive Oxygen Species; Receptors, Angiotensin; Renin-Angiotensin System; Transforming Growth Factor beta | 2004 |
The chronic inflammatory hypothesis for the morbidity associated with morbid obesity: implications and effects of weight loss.
Topics: Acute-Phase Proteins; Adipose Tissue; Angiotensin II; Angiotensinogen; C-Reactive Protein; Humans; Inflammation; Insulin Resistance; Interleukin-6; Liver; Lymphotoxin-alpha; Morbidity; Obesity; Tumor Necrosis Factor-alpha; Weight Loss | 2004 |
Vascular stiffness: measurements, mechanisms and implications.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Arteries; Arteriosclerosis; Endothelium, Vascular; Estrogens; Humans; Inflammation; Nitric Oxide; Vascular Resistance | 2004 |
[Tissue consequence of renin-angiotensin system activation].
Topics: Angiotensin II; Arteriosclerosis; Blood Coagulation; Calcium; Humans; Hypertension; Inflammation; Receptors, Cell Surface; Renin-Angiotensin System; Signal Transduction; Vacuolar Proton-Translocating ATPases; Vasoconstrictor Agents | 2004 |
Hormones and the neovascularization process: role of angiotensin II.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bone Marrow Cells; Cell Differentiation; Cell Hypoxia; Endothelium, Vascular; Humans; Inflammation; Neovascularization, Physiologic; Renin-Angiotensin System; Stem Cells | 2005 |
Molecular and cellular mechanisms in vascular injury in hypertension: role of angiotensin II.
Topics: Angiotensin II; Humans; Hypertension; Inflammation; Vascular Diseases | 2005 |
Of the renin-angiotensin system and reactive oxygen species Type 2 diabetes and angiotensin II inhibition.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Humans; Inflammation; Insulin Resistance; Metabolic Syndrome; Obesity; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2005 |
Is angiotensin-II an endogenous pro-inflammatory molecule?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Free Radicals; Humans; Inflammation; Inflammation Mediators; Male; Models, Biological; Neoplasms; Nitric Oxide; Pregnancy | 2005 |
Angiotensin II and vascular inflammation.
Topics: Angiotensin II; Animals; Blood Vessels; Capillary Permeability; Cyclooxygenase 2; Endothelin-1; Humans; Inflammation; Membrane Proteins; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Signal Transduction | 2005 |
Angiotensin-II behaves as an endogenous pro-inflammatory molecule.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cytokines; Fatty Acids, Unsaturated; Humans; Inflammation; Oxidative Stress; Receptors, Angiotensin | 2005 |
Effect of omapatrilat on the aging process of the normal rat.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Atrial Natriuretic Factor; Cardiovascular System; Cognition; Inflammation; Kidney; Nitric Oxide Synthase; Protease Inhibitors; Pyridines; Rats; Renin-Angiotensin System; Thiazepines; Vasoconstriction; Vasodilation | 2005 |
Pathogenic role of the renin-angiotensin system in modulating radiation-induced late effects.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Brain; Captopril; Humans; Inflammation; Kidney; Lung; NADP; Neoplasms; Oxidative Stress; Radiation Injuries; Radiation Pneumonitis; Reactive Oxygen Species; Renin-Angiotensin System; Survivors | 2006 |
Renal and vascular hypertension-induced inflammation: role of angiotensin II.
Topics: Angiotensin II; Chemokines; Cytokines; Female; Humans; Hypertension; Hypertension, Renal; Inflammation; Inflammation Mediators; Male; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Risk Factors; Sensitivity and Specificity | 2006 |
[Renin-angiotensin system in atherosclerosis].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Disease Progression; Endothelium, Vascular; Humans; Inflammation; Reactive Oxygen Species; Renin-Angiotensin System | 2006 |
Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Arteries; Humans; Hypertension; Inflammation; Mineralocorticoid Receptor Antagonists; Renin; Renin-Angiotensin System | 2006 |
Is hypertension an inflammatory process?
Topics: Angiotensin II; C-Reactive Protein; Humans; Hypertension; Inflammation; Interleukin-1; Interleukin-6; Oxidative Stress; Tumor Necrosis Factor-alpha | 2006 |
Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; E-Selectin; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukins; Renin-Angiotensin System; Tumor Necrosis Factor-alpha | 2006 |
[AII and inflammation].
Topics: Angiotensin II; Animals; Arteriosclerosis; Capillary Permeability; Cell Adhesion Molecules; Cytokines; Humans; Inflammation; Inflammation Mediators; Leukocytes; NF-kappa B; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Transcription, Genetic | 2006 |
[Oxidative stress].
Topics: Angiotensin II; Arteriosclerosis; Humans; Hypertension; Inflammation; Lipoproteins, LDL; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Risk Factors | 2006 |
Angiotensin, bradykinin and the endothelium.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Atherosclerosis; Bradykinin; Bradykinin Receptor Antagonists; Endothelium, Vascular; Humans; Hypertension; Inflammation; Peptides; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Bradykinin; Signal Transduction | 2006 |
The metabolic syndrome: role of skeletal muscle metabolism.
Topics: Angiotensin II; Cytokines; Energy Metabolism; Humans; Hypertension; Inflammation; Insulin; Metabolic Syndrome; Mitochondria; Muscle, Skeletal; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2006 |
Angiotensin II and inflammation: the effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Humans; Inflammation; Oxidative Stress | 2007 |
Macroangiopathy in adults and children with diabetes: from molecular mechanisms to vascular damage (part 1).
Topics: Adult; Angiotensin I; Angiotensin II; Atherosclerosis; Child; Cholesterol, LDL; Diabetic Angiopathies; Fatty Liver; Humans; Inflammation; Macrophages; Thrombosis | 2006 |
Type 2 diabetes and cardiovascular disease: getting to the fat of the matter.
Topics: Adiponectin; Adipose Tissue; Angiotensin II; Animals; Cardiovascular Diseases; Complement Activation; Complement C3a; Complement Factor D; Cytokines; Diabetes Mellitus, Type 2; Fibrinolysis; Humans; Inflammation; Insulin Resistance; Interleukin-6; Leptin; Nicotinamide Phosphoribosyltransferase; Obesity; Plasminogen Activator Inhibitor 1; Renin-Angiotensin System; Resistin; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Risk Factors; Tumor Necrosis Factor-alpha | 2007 |
[Angiotensin II activation of utilization of biological debris in the arterial intima via endogenous inflammation].
Topics: Angiotensin II; Animals; Arteries; Endothelium, Vascular; Humans; Inflammation; Tunica Intima | 2007 |
Oxidative damage pathways in relation to normal tissue injury.
Topics: Angiotensin II; Animals; Humans; Inflammation; Oxidative Stress; Radiation Injuries; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction | 2007 |
Regulatory mechanisms of atrial fibrotic remodeling in atrial fibrillation.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Atrial Fibrillation; Endomyocardial Fibrosis; Heart Atria; Humans; Inflammation; Matrix Metalloproteinases; Models, Biological; Oxidative Stress; Peptide Fragments; ras GTPase-Activating Proteins; Signal Transduction; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta1; Ventricular Remodeling | 2008 |
Role of bone marrow renin-angiotensin system in the pathogenesis of atherosclerosis.
Topics: Angiotensin II; Animals; Atherosclerosis; Bone Marrow; Humans; Inflammation; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2008 |
[Polypeptides and antagonists].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Humans; Hypertension; Inflammation; Kallikreins; Kinins; Neurotensin; Peptides; Renin-Angiotensin System; Substance P; Vasoactive Intestinal Peptide | 1984 |
Impaired proteolytic activity as a potential cause of progressive renal disease.
Topics: Acidosis; Ammonia; Angiotensin II; Animals; Diabetes Mellitus, Experimental; Dietary Proteins; Endopeptidases; Glomerulonephritis; Humans; Hypertrophy; Inflammation; Insulin-Like Growth Factor I; Kidney; Kidney Diseases; Proteins; Transforming Growth Factor beta | 1996 |
Chymase: its pathophysiological roles and inhibitors.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiovascular Diseases; Chymases; Cytokines; Humans; Inflammation; Peptidyl-Dipeptidase A; Serine Endopeptidases; Serine Proteinase Inhibitors; Species Specificity; Structure-Activity Relationship | 1998 |
Angiotensin, inflammation, hypertension, and cardiovascular disease.
Topics: Angiotensin II; Cardiovascular Diseases; Humans; Hypertension; Inflammation; NF-kappa B; Vasoconstrictor Agents | 2001 |
Proinflammatory actions of angiotensins.
Topics: Angiotensin II; Animals; Humans; Inflammation; Renin-Angiotensin System | 2001 |
Modulating angiotensin II-induced inflammation by HMG Co-A reductase inhibition.
Topics: Angiotensin II; Animals; Heart; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Kidney; Pyridines | 2001 |
Proinflammatory effects of angiotensin II and endothelin: targets for progression of cardiovascular and renal diseases.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Disease Progression; Endothelins; Humans; Inflammation; Kidney Diseases; Nitric Oxide; Receptor, Angiotensin, Type 1 | 2002 |
The inflammatory component in progressive renal disease--are interventions possible?
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Fibrosis; Humans; Inflammation; Inflammation Mediators; Kidney Diseases; Models, Biological; Mycophenolic Acid; Nephritis; Renin-Angiotensin System; Transforming Growth Factor beta | 2002 |
Angiotensin II as a pro-inflammatory mediator.
Topics: Angiotensin II; Animals; Arteriosclerosis; Cell Adhesion; Chemotaxis; Cytokines; Endothelium, Vascular; Growth Substances; Humans; Inflammation; Macrophages; Muscle, Smooth, Vascular; NF-kappa B; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin | 2002 |
12 trial(s) available for angiotensin ii and Innate Inflammatory Response
Article | Year |
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Topics: Acoustics; Adsorption; Angiotensin II; Animals; Anti-Bacterial Agents; Azithromycin; Calcium; Carbon; Charcoal; Child; Chlorides; Copper; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Resistance, Bacterial; Ecosystem; Epigenesis, Genetic; Female; Fibroblasts; Fibrosis; Gallium Radioisotopes; Heterozygote; Hot Temperature; Humans; Hydrogen-Ion Concentration; Inflammasomes; Inflammation; Kinetics; Macrolides; Magnetic Resonance Imaging; Malawi; Male; Mass Drug Administration; Methylene Blue; Mice; Neuroendocrine Tumors; NLR Family, Pyrin Domain-Containing 3 Protein; Octreotide; Organometallic Compounds; Oxidative Stress; Phenotype; Positron-Emission Tomography; Prevalence; Prognosis; Rats; Receptors, Somatostatin; Retrospective Studies; Rivers; Streptococcus pneumoniae; Trachoma; Water Pollutants, Chemical; Zinc Compounds | 2022 |
Progressive resistance training ameliorates deteriorating cardiac autonomic dysfunction, subclinical inflammation and endothelial dysfunction in type 2 diabetes mellitus: A randomized control trial.
Topics: Angiotensin II; Autonomic Nervous System Diseases; Biomarkers; Diabetes Mellitus, Type 2; Humans; Inflammation; Resistance Training; Vascular Diseases | 2023 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Haemostatic and inflammatory alterations in familial hypercholesterolaemia, and the impact of angiotensin II infusion.
Topics: Adult; Angiotensin II; Antifibrinolytic Agents; Biomarkers; Blood Pressure; Calibration; Case-Control Studies; Demography; Female; Fibrinolysin; Heart Rate; Hemostasis; Humans; Hyperlipoproteinemia Type II; Inflammation; Interleukin-6; Leukocytes; Male; Peptide Fragments; Placebos; Plasminogen Activator Inhibitor 1; Prothrombin | 2015 |
RAAS Activation Is Associated With Visceral Adiposity and Insulin Resistance Among HIV-infected Patients.
Topics: Adiposity; Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; HIV Infections; HIV-1; Humans; Inflammation; Insulin Resistance; Intra-Abdominal Fat; Male; Middle Aged; Obesity, Abdominal; Renin-Angiotensin System; Young Adult | 2015 |
Relationship between Angiotensin Converting Enzyme, Apelin, and New-Onset Atrial Fibrillation after Off-Pump Coronary Artery Bypass Grafting.
Topics: Aged; Angiotensin II; Apelin; Atrial Fibrillation; Bradykinin; C-Reactive Protein; Case-Control Studies; Coronary Artery Bypass, Off-Pump; Female; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Malondialdehyde; Middle Aged; Multivariate Analysis; Oxidative Stress; Peptidyl-Dipeptidase A; Postoperative Complications; Postoperative Period; Preoperative Period; Retrospective Studies; Risk Factors | 2017 |
Effect of fosinopril treatment on serum C-reactive protein levels in patients with microalbuminuria.
Topics: Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; C-Reactive Protein; Double-Blind Method; Female; Fosinopril; Humans; Inflammation; Male; Middle Aged; Odds Ratio; Renin-Angiotensin System; Sex Factors | 2008 |
Angiotensin II type 1 receptor antagonism improves hypercholesterolemia-associated endothelial dysfunction.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cholesterol, LDL; Double-Blind Method; Endothelium, Vascular; Felodipine; Female; Forearm; Humans; Hypercholesterolemia; Inflammation; Male; Middle Aged; Prospective Studies; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Regional Blood Flow; Tetrazoles | 2002 |
Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Collagen; Combined Modality Therapy; Cyclooxygenase 1; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endarterectomy, Carotid; Enzyme Induction; Extracellular Matrix; Female; Gene Expression Regulation; Humans; Inflammation; Intramolecular Oxidoreductases; Irbesartan; Isoenzymes; Macrophages; Male; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Protease Inhibitors; Rupture, Spontaneous; Tetrazoles | 2004 |
Simvastatin reduces interleukin-1beta secretion by peripheral blood mononuclear cells in patients with essential hypertension.
Topics: Aged; Angiotensin II; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Inflammation; Interleukin-1; Leukocytes, Mononuclear; Lipids; Male; Middle Aged; Simvastatin; Tetrazoles; Valine; Valsartan | 2004 |
Influence of angiotensin-converting enzyme inhibitor enalaprilat on endothelial-derived substances in the critically ill.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cell Adhesion Molecules; Critical Illness; Double-Blind Method; Enalaprilat; Endothelin-1; Endothelium, Vascular; Female; Hemodynamics; Humans; Inflammation; Male; Middle Aged; Prospective Studies; Sepsis; Survival Analysis; Thrombomodulin | 1998 |
Angiotensin II receptor-independent antiinflammatory and antiaggregatory properties of losartan: role of the active metabolite EXP3179.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arachidonic Acid; Biotransformation; Cells, Cultured; Cyclooxygenase 2; Dinoprost; Drug Design; Endothelium, Vascular; Enzyme Activation; Female; Humans; Hypertension; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; Isoenzymes; Lipopolysaccharides; Losartan; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Thromboxane A2; Up-Regulation; Vasoconstrictor Agents | 2002 |
500 other study(ies) available for angiotensin ii and Innate Inflammatory Response
Article | Year |
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Elevated reactivity of Apelin inhibited renal fibrosis induced by chronic intermittent hypoxia.
Topics: Angiotensin II; Animals; Apelin; Apelin Receptors; Cell Line; Fibrosis; Humans; Hypoxia; Inflammation; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Male; Nitrobenzoates; Oxidative Stress; Pyrans; Rats, Wistar | 2021 |
Circular RNA Cdyl promotes abdominal aortic aneurysm formation by inducing M1 macrophage polarization and M1-type inflammation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; RNA, Circular | 2022 |
T Cell-based RAS Activity and Insulin Levels in Obese Subjects with Low Grade Inflammation.
Topics: Angiotensin II; C-Reactive Protein; Cytokines; Humans; Inflammation; Insulin; Insulin Resistance; Obesity; Peptidyl-Dipeptidase A; Renin-Angiotensin System; T-Lymphocytes | 2022 |
Potential of Gold Nanoparticles for Noninvasive Imaging and Therapy for Vascular Inflammation.
Topics: Angiotensin II; Animals; Apolipoproteins E; Contrast Media; Gold; Inflammation; Metal Nanoparticles; Mice; Mice, Inbred Strains; Tomography, X-Ray Computed | 2022 |
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway.
Topics: Angiotensin II; Animals; Cardiomegaly; Caveolin 1; Cells, Cultured; Fibrosis; Inflammation; Male; Mice; Mice, Inbred C57BL; Myocardium; Rats; Rats, Sprague-Dawley; Signal Transduction; Ultrasonic Waves | 2021 |
Interferon-stimulated gene 15 pathway is a novel mediator of endothelial dysfunction and aneurysms development in angiotensin II infused mice through increased oxidative stress.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Carotid Intima-Media Thickness; Elastin; Humans; Hypertension; Inflammation; Interferons; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2022 |
Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti-hypertension effect.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blood Pressure; Disease Models, Animal; Drugs, Chinese Herbal; Gene Knockdown Techniques; Heart Rate; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Vascular Remodeling | 2022 |
MicroRNA-451a attenuates angiotensin II-induced cardiac fibrosis and inflammation by directly targeting T-box1.
Topics: Angiotensin II; Animals; Fibrosis; Inflammation; Mice; Mice, Inbred C57BL; MicroRNAs; Myocardium; Myocytes, Cardiac | 2022 |
Continuous Infusion of Angiotensin IV Protects against Acute Myocardial Infarction via the Inhibition of Inflammation and Autophagy.
Topics: Angiotensin II; Animals; Apoptosis; Autophagy; Cardiomyopathies; Cells, Cultured; Inflammation; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; Oxidative Stress; Protective Agents; Rats | 2021 |
Platelet protects angiotensin II-driven abdominal aortic aneurysm formation through inhibition of inflammation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Platelets; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout | 2022 |
Angiotensin II enhances group 2 innate lymphoid cell responses via AT1a during airway inflammation.
Topics: Angiotensin II; Animals; Biomarkers; Bronchial Hyperreactivity; Disease Models, Animal; Disease Susceptibility; Immunity, Innate; Inflammation; Interleukin-33; Lymphocyte Subsets; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Respiratory Tract Diseases | 2022 |
Dihydroartemisinin alleviates AngII-induced vascular smooth muscle cell proliferation and inflammatory response by blocking the FTO/NR4A3 axis.
Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Angiotensin II; Animals; Artemisinins; Cell Proliferation; Cells, Cultured; DNA-Binding Proteins; Inflammation; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Receptors, Steroid; Receptors, Thyroid Hormone; Signal Transduction | 2022 |
CCL17 Aggravates Myocardial Injury by Suppressing Recruitment of Regulatory T Cells.
Topics: Angiotensin II; Animals; Chemokine CCL17; Diphtheria Toxin; Heart Failure; Humans; Inflammation; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Phenylephrine; T-Lymphocytes, Regulatory; Ventricular Remodeling | 2022 |
Topics: Angiotensin II; Animals; Carrier Proteins; Fibrosis; Hypertension; Inflammasomes; Inflammation; Mice; MicroRNAs; NLR Family, Pyrin Domain-Containing 3 Protein; Thioredoxins | 2022 |
MicroRNA-122-5p Aggravates Angiotensin II-Mediated Myocardial Fibrosis and Dysfunction in Hypertensive Rats by Regulating the Elabela/Apelin-APJ and ACE2-GDF15-Porimin Signaling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apelin; Cardiomyopathies; Fibrosis; Growth Differentiation Factor 15; Hypertension; Inflammation; MicroRNAs; Rats | 2022 |
Carbon monoxide releasing molecule-2 attenuates angiotensin II-induced IL-6/Jak2/Stat3-associated inflammation by inhibiting NADPH oxidase- and mitochondria-derived ROS in human aortic smooth muscle cells.
Topics: Angiotensin II; Anti-Inflammatory Agents; Carbon Monoxide; Humans; Inflammation; Interleukin-6; Janus Kinase 2; Mitochondria; Myocytes, Smooth Muscle; NADPH Oxidases; NF-E2-Related Factor 2; Organometallic Compounds; Reactive Oxygen Species; STAT3 Transcription Factor | 2022 |
Renal artery occlusive disease, renin-angiotensin-aldosterone, inflammation, and refractory arterial hypertension, a half-century's perspective.
Topics: Aldosterone; Angiotensin II; Angiotensins; Blood Pressure; Humans; Hypertension; Inflammation; Renal Artery; Renin; Renin-Angiotensin System | 2022 |
Pleiotropic effects of AT-1 receptor antagonists in hypoxia induced by cardiac ischaemia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Cells, Cultured; Coronary Artery Disease; Humans; Hypoxia; Inflammation; Ischemia; Myocytes, Cardiac; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1 | 2022 |
Oridonin Relieves Angiotensin II-Induced Cardiac Remodeling via Inhibiting GSDMD-Mediated Inflammation.
Topics: Angiotensin II; Animals; Diterpenes, Kaurane; Inflammation; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphate-Binding Proteins; Pore Forming Cytotoxic Proteins; Rats; Ventricular Remodeling | 2022 |
Ginkgolide A alleviates cardiac remodeling in mice with myocardial infarction via binding to matrix metalloproteinase-9 to attenuate inflammation.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cardiotonic Agents; Fibronectins; Fibrosis; Ginkgolides; Heart Diseases; Inflammation; Lactones; Matrix Metalloproteinase 9; Mice; Myocardial Infarction; Myocytes, Cardiac; Rats; Ventricular Remodeling | 2022 |
Tumor Necrosis Factor-
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Inflammation; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Interleukin-22 exacerbates angiotensin II-induced hypertensive renal injury.
Topics: Angiotensin II; Animals; Fibrosis; Humans; Hypertension; Inflammation; Interleukin-22; Interleukins; Kidney; Kidney Diseases; Mice; Mice, Inbred C57BL | 2022 |
Chicken Muscle-Derived ACE2 Upregulating Peptide VVHPKESF Inhibits Angiotensin II-Stimulated Inflammation in Vascular Smooth Muscle Cells
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Chickens; Inflammation; Muscle, Smooth, Vascular; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Rats; Receptors, G-Protein-Coupled | 2022 |
Interleukin 17A infusion has no acute or long-term hypertensive action in conscious unrestrained male mice.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Inflammation; Interleukin-17; Interleukin-6; Male; Mice | 2022 |
Mediterranean G6PD variant rats are protected from Angiotensin II-induced hypertension and kidney damage, but not from inflammation and arterial stiffness.
Topics: Actins; Angiotensin II; Animals; Glucosephosphate Dehydrogenase Deficiency; Humans; Hypertension; Inflammation; Inositol; Interleukin-6; Kidney; Myosin Heavy Chains; Phosphates; Rats; Superoxides; Vascular Stiffness | 2022 |
Corynoline protects ang II-induced hypertensive heart failure by increasing PPARα and Inhibiting NF-κB pathway.
Topics: Angiotensin II; Animals; Berberine Alkaloids; Fibrosis; Heart Failure; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; NF-kappa B; PPAR alpha; RNA | 2022 |
Tabersonine attenuates Angiotensin II-induced cardiac remodeling and dysfunction through targeting TAK1 and inhibiting TAK1-mediated cardiac inflammation.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibrosis; Heart Failure; Indole Alkaloids; Inflammation; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Quinolines; Rats; Signal Transduction; Ventricular Remodeling | 2022 |
Targeting inflammation and redox perturbations by lisinopril mitigates Freund's adjuvant-induced arthritis in rats: role of JAK-2/STAT-3/RANKL axis, MMPs, and VEGF.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cytokines; Freund's Adjuvant; Inflammation; Interleukin-17; Interleukin-6; Lipid Peroxides; Lisinopril; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; NF-E2-Related Factor 2; NF-kappa B; Oxidation-Reduction; Rats; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2022 |
Essential role of Nrf2 in sulforaphane-induced protection against angiotensin II-induced aortic injury.
Topics: Angiotensin II; Animals; Glycogen Synthase Kinase 3 beta; Inflammation; Isothiocyanates; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Sulfoxides | 2022 |
Exerkine fibronectin type-III domain-containing protein 5/irisin-enriched extracellular vesicles delay vascular ageing by increasing SIRT6 stability.
Topics: Aged; Aging; Angiotensin II; Animals; Child, Preschool; Extracellular Vesicles; Fibronectins; HSP40 Heat-Shock Proteins; Humans; Inflammation; Mice; Mice, Knockout; Muscle, Skeletal; Sirtuins; Transcription Factors | 2022 |
Pharmaceutical Potential of Casein-Derived Tripeptide Met-Lys-Pro: Improvement in Cognitive Impairments and Suppression of Inflammation in APP/PS1 Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Caseins; Cognitive Dysfunction; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidases; Oligopeptides; Pharmaceutical Preparations; Presenilin-1; Receptors, Angiotensin; Tumor Necrosis Factor-alpha | 2022 |
Diacerein alleviates Ang II-induced cardiac inflammation and remodeling by inhibiting the MAPKs/c-Myc pathway.
Topics: Angiotensin II; Animals; Anthraquinones; Cardiomegaly; Cardiomyopathies; Fibrosis; Heart Failure; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; RNA; Ventricular Remodeling | 2022 |
Contrasting effects of sleep fragmentation and angiotensin-II treatment upon pro-inflammatory responses of mice.
Topics: Angiotensin II; Animals; Corticosterone; Cytokines; Inflammation; Male; Mice; Mice, Inbred C57BL; Renin-Angiotensin System; Sleep Deprivation | 2022 |
Effect of angiotensin II pathway inhibitors on post-surgical adhesion band formation: a potential repurposing of old drugs.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Drug Repositioning; Enalapril; Eosine Yellowish-(YS); Fibrosis; Hematoxylin; Inflammation; Pharmaceutical Preparations; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Telmisartan; Tissue Adhesions | 2022 |
Activation of AMP-activated protein kinase ablated the formation of aortic dissection by suppressing vascular inflammation and phenotypic switching of vascular smooth muscle cells.
Topics: Adenosine Monophosphate; AMP-Activated Protein Kinases; Angiotensin II; Animals; Aortic Dissection; Cells, Cultured; Humans; Inflammation; Mice; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle | 2022 |
BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Epigenesis, Genetic; Homeostasis; Humans; Inflammation; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle | 2022 |
Qingda granule alleviate angiotensin ⅱ-induced hypertensive renal injury by suppressing oxidative stress and inflammation through NOX1 and NF-κB pathways.
Topics: Angiotensin II; Animals; Drugs, Chinese Herbal; Hypertension; Inflammation; Kidney; Mice; NF-kappa B; Nitrogen Oxides; Oxidative Stress | 2022 |
Inhibition of MyD88 attenuates angiotensin II-induced hypertensive kidney disease via regulating renal inflammation.
Topics: Angiotensin II; Animals; Cytokines; Fibrosis; Hypertension; Hypertension, Renal; Inflammation; Kidney; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; NF-kappa B; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4 | 2022 |
Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; COVID-19; Cricetinae; Cytokines; Diet; Disease Models, Animal; Dyslipidemias; Humans; Inflammation; Mesocricetus; Non-alcoholic Fatty Liver Disease; Obesity; SARS-CoV-2 | 2022 |
Angiotensin II type-2 receptor activation in alveolar macrophages mediates protection against cigarette smoke-induced chronic obstructive pulmonary disease.
Topics: Angiotensin II; Animals; Cigarette Smoking; Imidazoles; Inflammation; Macrophages, Alveolar; Mice; Mitogen-Activated Protein Kinase Phosphatases; NF-kappa B; Nicotiana; Pulmonary Disease, Chronic Obstructive; Receptor, Angiotensin, Type 2; Sirtuin 1; Sulfonamides; Thiophenes | 2022 |
Oviductal Glycoprotein 1 Promotes Hypertension by Inducing Vascular Remodeling Through an Interaction With MYH9.
Topics: Angiotensin II; Animals; Cytoskeletal Proteins; Glycoproteins; Hypertension; Inflammation; Mice; Mice, Knockout; Mice, Transgenic; Myosin Heavy Chains; Vascular Remodeling | 2022 |
Sclareol attenuates angiotensin II-induced cardiac remodeling and inflammation via inhibiting MAPK signaling.
Topics: Angiotensin II; Animals; Fibrosis; Heart Failure; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardium; Myocytes, Cardiac; Ventricular Remodeling | 2023 |
Cardiomyocyte p38 MAPKα suppresses a heart-adipose tissue-neutrophil crosstalk in heart failure development.
Topics: Adipose Tissue; Angiotensin II; Animals; Cardiomegaly; Fatty Acids; Heart Failure; Inflammation; Lipase; Lipids; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Neutrophils; p38 Mitogen-Activated Protein Kinases; Tamoxifen | 2022 |
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease Models, Animal; Elastin; Humans; Inflammation; Matrix Metalloproteinase 8; Mice; Mice, Knockout; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2022 |
LOX-1 deficiency increases ruptured abdominal aortic aneurysm via thinning of adventitial collagen.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atherosclerosis; Collagen; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Scavenger Receptors, Class E | 2023 |
Serum levels of autoantibodies against the angiotensin II type I receptor are not associated with serum dicarbonyl or AGE levels in patients with an aldosterone-producing adenoma.
Topics: Adenoma; Aldosterone; Angiotensin II; Autoantibodies; Chromatography, Liquid; Glycation End Products, Advanced; Glyoxal; Humans; Inflammation; Magnesium Oxide; Pyruvaldehyde; Receptor, Angiotensin, Type 1; Tandem Mass Spectrometry | 2023 |
AT1 receptor autoantibodies mediate effects of metabolic syndrome on dopaminergic vulnerability.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Autoantibodies; Dopamine; Dopaminergic Neurons; Endothelial Cells; Humans; Inflammation; Metabolic Syndrome; Neuroinflammatory Diseases; Parkinson Disease; Rats; Receptor, Angiotensin, Type 1 | 2023 |
The systemic and hepatic alternative renin-angiotensin system is activated in liver cirrhosis, linked to endothelial dysfunction and inflammation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Chymases; Humans; Hypertension, Portal; Inflammation; Liver Cirrhosis; Peptidyl-Dipeptidase A; Prospective Studies; Renin-Angiotensin System; Vascular Diseases | 2023 |
ADAR1 Non-Editing Function in Macrophage Activation and Abdominal Aortic Aneurysm.
Topics: Adenosine Deaminase; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; I-kappa B Kinase; Inflammation; Macrophage Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; NF-kappa B; RNA-Binding Proteins | 2023 |
Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure.
Topics: Angiotensin II; Autoantibodies; Heart Failure; Humans; Immunoglobulin G; Inflammation; Receptors, G-Protein-Coupled | 2023 |
Cordycepin suppresses vascular inflammation, apoptosis and oxidative stress of arterial smooth muscle cell in thoracic aortic aneurysm with VEGF inhibition.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Apoptosis; Calcium Chloride; Humans; Inflammation; Interleukin-6; Myocytes, Smooth Muscle; Oxidative Stress; Rats; Vascular Endothelial Growth Factor A | 2023 |
ACE2/ANG-(1-7)/Mas receptor axis activation prevents inflammation and improves cognitive functions in streptozotocin induced rat model of Alzheimer's disease-like phenotypes.
Topics: Acetylcholine; Alzheimer Disease; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cognition; Inflammation; Peptide Fragments; Peptidyl-Dipeptidase A; Phenotype; Rats; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Streptozocin | 2023 |
Waterpipe smoke inhalation potentiates cardiac oxidative stress, inflammation, mitochondrial dysfunction, apoptosis and autophagy in experimental hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Hypertension; Inflammation; Mice; Mitochondria; Myocytes, Cardiac; Oxidative Stress; Water Pipe Smoking | 2023 |
Targeting mitochondrial stress with Szeto-Schiller 31 prevents experimental abdominal aortic aneurysm: Crosstalk with endoplasmic reticulum stress.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Endoplasmic Reticulum Stress; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Reactive Oxygen Species | 2023 |
Taxifolin ameliorates abdominal aortic aneurysm by preventing inflammation and apoptosis and extracellular matrix degradation via inactivating TLR4/NF-κB axis.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Disease Models, Animal; Extracellular Matrix; Humans; Inflammation; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; NF-kappa B; Toll-Like Receptor 4 | 2023 |
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Scavenger | 2023 |
Vitamin D deficiency enhances vascular oxidative stress, inflammation, and angiotensin II levels in the microcirculation of diabetic patients.
Topics: Angiotensin II; Diabetes Mellitus, Type 2; Humans; Inflammation; Microcirculation; Oxidative Stress; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vitamin D Deficiency | 2023 |
SIRT6 is an epigenetic repressor of thoracic aortic aneurysms via inhibiting inflammation and senescence.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Epigenesis, Genetic; Humans; Inflammation; Mice; Sirtuins | 2023 |
Cardioprotective Effects of Sodium Glucose Cotransporter 2 Inhibition in Angiotensin II-Dependent Hypertension Are Mediated by the Local Reduction of Sympathetic Activity and Inflammation.
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Cardiomegaly; Fibrosis; Hypertension; Inflammation; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Tyrosine 3-Monooxygenase | 2023 |
Resolvin E1/ChemR23 Protects Against Hypertension and Vascular Remodeling in Angiotensin II-Induced Hypertensive Mice.
Topics: Angiotensin II; Animals; Chemokines; Eicosapentaenoic Acid; Humans; Hypertension; Inflammation; Intercellular Signaling Peptides and Proteins; Mice; NF-E2-Related Factor 2; NF-kappa B; Peptide Hormones; Vascular Remodeling | 2023 |
CD73 deficiency does not aggravate angiotensin II-induced aortic inflammation in mice.
Topics: 5'-Nucleotidase; Adenosine; Angiotensin II; Animals; Female; Inflammation; Male; Mice; Mice, Knockout | 2023 |
Aqueous Fraction from
Topics: Angiotensin II; Animals; Blood Pressure; Cucumis sativus; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Peptide Hormones; Plant Components, Aerial; Proto-Oncogene Proteins c-akt; Vascular Remodeling | 2023 |
ATRQβ-001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Calcium Phosphates; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteopontin; Random Allocation; Vaccines, Virus-Like Particle; Vasoconstrictor Agents | 2019 |
AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Heat Stroke; Hepatocytes; Humans; Imidazoles; Inflammasomes; Inflammation; Interleukin-1beta; Liver; Liver Cirrhosis; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Prospective Studies; Pyroptosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2019 |
Novel interaction of antioxidant-1 with TRAF4: role in inflammatory responses in endothelial cells.
Topics: Angiotensin II; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Copper; Copper Transport Proteins; Diet, High-Fat; Gene Expression Regulation; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Molecular Chaperones; NADPH Oxidases; Protein Binding; Protein Transport; Reactive Oxygen Species; RNA, Small Interfering; TNF Receptor-Associated Factor 4; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2019 |
Soluble RAGE attenuates AngII-induced endothelial hyperpermeability by disrupting HMGB1-mediated crosstalk between AT1R and RAGE.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Neoplasm; Aorta; Atherosclerosis; Cadherins; Capillary Permeability; Cardiovascular Diseases; Endothelial Cells; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Inflammation; Ligands; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Receptor, Angiotensin, Type 1; RNA, Small Interfering; Signal Transduction | 2019 |
Re: Circulating miR-103a-3p Contributes to Angiotensin II-Induced Renal Inflammation and Fibrosis via a SNRK/NF-κB/p65 Regulatory Axis.
Topics: Angiotensin II; Fibrosis; Humans; Inflammation; MicroRNAs; Protein Serine-Threonine Kinases | 2020 |
Biochanin A protects against angiotensin II-induced damage of dopaminergic neurons in rats associated with the increased endophilin A2 expression.
Topics: Acyltransferases; Angiotensin II; Animals; Dopaminergic Neurons; Genistein; Inflammation; Lipopolysaccharides; Male; Microglia; Neuroimmunomodulation; Nitric Oxide; Phytoestrogens; Protective Agents; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled | 2019 |
BRD4 blockage alleviates pathological cardiac hypertrophy through the suppression of fibrosis and inflammation via reducing ROS generation.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Line; Fibrosis; Heart; Heme Oxygenase-1; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; NF-kappa B; Nuclear Proteins; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Signal Transduction; Transcription Factors; Transforming Growth Factor beta1; Up-Regulation | 2020 |
Cardiomyocyte-Specific
Topics: Angiotensin II; Animals; Cell Line; Endothelial Cells; Fibrosis; Heart; Heart Failure; In Vitro Techniques; Inflammation; Macrophages; Mice; Mice, Knockout; Myocardium; Myocytes, Cardiac; NF-kappa B; Protein Serine-Threonine Kinases; Vasoconstrictor Agents; Ventricular Dysfunction, Left | 2019 |
IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Dissection; Apoptosis; Case-Control Studies; Disease Models, Animal; Female; Humans; Inflammation; Interleukin-5; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; Myocytes, Smooth Muscle; Prognosis | 2020 |
Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress.
Topics: Angiotensin II; Animals; Desoxycorticosterone Acetate; Endothelium, Vascular; Essential Hypertension; Female; Heart; Inflammation; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mitochondria, Heart; Mitochondrial Proteins; Myocardium; Oxidative Stress; Sirtuin 3 | 2020 |
Repeated Porphyromonas gingivalis W83 exposure leads to release pro-inflammatory cytokynes and angiotensin II in coronary artery endothelial cells.
Topics: Angiotensin II; Atherosclerosis; Chemokine CCL2; Coronary Vessels; Endothelial Cells; Flow Cytometry; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypertension; Inflammation; Interleukin-6; Lipopolysaccharides; Periodontitis; Porphyromonas gingivalis; Receptor, Angiotensin, Type 1; RNA, Messenger | 2019 |
Contribution of angiotensin II in hepatic ischemia /reperfusion induced lung injury: Acute versus chronic usage of captopril.
Topics: Actins; Acute Lung Injury; Angiotensin II; Animals; Captopril; Inflammation; Kupffer Cells; Liver; Lung; Male; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Hypersensitivity; Tumor Necrosis Factor-alpha | 2020 |
Neuron-derived orphan receptor-1 modulates cardiac gene expression and exacerbates angiotensin II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Biomarkers; Cardiomegaly; Collagen; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Disease Progression; Electrocardiography; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Inflammation; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Nuclear Receptor Subfamily 4, Group A, Member 3; Transcription, Genetic; Ventricular Remodeling | 2020 |
Resveratrol suppresses interleukin-6 expression through activation of sirtuin 1 in hypertrophied H9c2 cardiomyoblasts.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Survival; Cells, Cultured; Gene Expression; Inflammation; Interleukin-6; Myocytes, Cardiac; Rats; Resveratrol; RNA, Messenger; Sirtuin 1; Transcription, Genetic | 2020 |
The Demonstration of an Aqp4/Tgf-beta 1 Pathway in Murine Astrocytes Holds Implications for Both Neuromyelitis Optica and Progressive Multiple Sclerosis.
Topics: Angiotensin II; Animals; Aquaporin 4; Astrocytes; Disease Progression; Inflammation; Mice; Multiple Sclerosis; Neuromyelitis Optica; Signal Transduction; Transforming Growth Factor beta1 | 2020 |
Amphetamine-induced sensitization of hypertension and lamina terminalis neuroinflammation.
Topics: Amphetamine; Angiotensin II; Animals; Blood Pressure; Central Nervous System Stimulants; Diet, High-Fat; Disease Models, Animal; Hypertension; Hypothalamus; Inflammation; Paraventricular Hypothalamic Nucleus; Rats | 2020 |
Macrophage-derived sulfur dioxide is a novel inflammation regulator.
Topics: Angiotensin II; Animals; Aspartate Aminotransferases; Cell Line; Chemotaxis; Gene Expression Regulation; Inflammation; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Myocytes, Smooth Muscle; NF-kappa B; Rats; RAW 264.7 Cells; RNA, Small Interfering; Signal Transduction; Sulfites; Sulfur Dioxide; Tumor Necrosis Factor-alpha | 2020 |
Pro-inflammatory cytokines in the paraventricular nucleus mediate the adipose afferent reflex in rats.
Topics: Adipose Tissue, White; Angiotensin II; Animals; Blood Pressure; Cytokines; Heart; Inflammation; Interleukin-1beta; Kidney; Losartan; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System; Tumor Necrosis Factor-alpha | 2020 |
STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stress.
Topics: Angiotensin II; Animals; Biomarkers; Cardiomegaly; Disease Models, Animal; Disease Susceptibility; Echocardiography; Endoplasmic Reticulum Stress; Fibrosis; Gene Expression; Gene Knockdown Techniques; Immunohistochemistry; Inflammation; Male; Membrane Proteins; Mice; Myocytes, Cardiac; Rats; Signal Transduction | 2020 |
Central CYP1B1 (Cytochrome P450 1B1)-Estradiol Metabolite 2-Methoxyestradiol Protects From Hypertension and Neuroinflammation in Female Mice.
Topics: 2-Methoxyestradiol; Angiotensin II; Animals; Astrocytes; Baroreflex; Blood Pressure; Brain; Cytochrome P-450 CYP1B1; Estradiol; Female; Hypertension; Inflammation; Mice; Mice, Knockout; Microglia; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species | 2020 |
[Inhibitors of RAS Might Be a Good Choice for the Therapy of COVID-19 Pneumonia].
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Betacoronavirus; Blood Pressure; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Inflammation; Lung; Peptide Fragments; Peptidyl-Dipeptidase A; Pneumonia, Viral; Prognosis; Renin-Angiotensin System; SARS-CoV-2 | 2020 |
Prevention of systemic inflammation and neuroprotective effects of Qingda granules against angiotensin II-mediated hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Astrocytes; Brain; Drugs, Chinese Herbal; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents | 2020 |
MRTF-A promotes angiotensin II-induced inflammatory response and aortic dissection in mice.
Topics: Angiotensin II; Animals; Aortic Dissection; Apoptosis; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Mice; Stress, Mechanical; Trans-Activators; Transcriptome; Tumor Necrosis Factor-alpha | 2020 |
MiR-144-5p limits experimental abdominal aortic aneurysm formation by mitigating M1 macrophage-associated inflammation: Suppression of TLR2 and OLR1.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Line; Cell Plasticity; Disease Models, Animal; Disease Susceptibility; Gene Expression; Humans; Inflammation; Macrophage Activation; Macrophages; Mice; Mice, Knockout; MicroRNAs; RAW 264.7 Cells; RNA Interference; Scavenger Receptors, Class E; Toll-Like Receptor 2 | 2020 |
Excessive EP4 Signaling in Smooth Muscle Cells Induces Abdominal Aortic Aneurysm by Amplifying Inflammation.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Calcium Chloride; Gene Expression; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Macrophages; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Mice, Transgenic; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein-Lysine 6-Oxidase; Receptors, Cytokine; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction | 2020 |
Bmal1 Deletion in Myeloid Cells Attenuates Atherosclerotic Lesion Development and Restrains Abdominal Aortic Aneurysm Formation in Hyperlipidemic Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; ARNTL Transcription Factors; Atherosclerosis; Cells, Cultured; Crosses, Genetic; Diet, High-Fat; Gene Deletion; Gene Expression; Hyperlipidemias; Inflammation; Integrases; Macrophages, Peritoneal; Mice; Mice, Knockout; Muramidase; Myeloid Cells; Promoter Regions, Genetic; Receptors, LDL | 2020 |
A Role of Inflammation and Immunity in Essential Hypertension-Modeled and Analyzed Using Petri Nets.
Topics: Angiotensin II; Autoantigens; Blood Coagulation; Bradykinin; C-Reactive Protein; Endothelium, Vascular; Essential Hypertension; Humans; Inflammation; Kallikrein-Kinin System; Lymphocyte Activation; Models, Biological; NADPH Oxidases; Natriuresis; Nitric Oxide; Nitric Oxide Synthase Type III; Renin-Angiotensin System; Skin; Sodium; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha | 2020 |
Role of microRNA 690 in Mediating Angiotensin II Effects on Inflammation and Endoplasmic Reticulum Stress.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Angiotensin II; Animals; Base Sequence; Biomarkers; Endoplasmic Reticulum Stress; Gene Expression Regulation; Inflammation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; MicroRNAs; Renin-Angiotensin System; Reproducibility of Results; Signal Transduction | 2020 |
Vascular Endothelial Growth Factor (VEGF) as a Vital Target for Brain Inflammation during the COVID-19 Outbreak.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Betacoronavirus; Blood-Brain Barrier; Brain; Coronavirus Infections; COVID-19; Cytokines; Humans; Inflammation; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; SARS-CoV-2; Vascular Endothelial Growth Factor A | 2020 |
Effect of Angiotensin II on Bone Erosion and Systemic Bone Loss in Mice with Tumor Necrosis Factor-Mediated Arthritis.
Topics: Angiotensin II; Animals; Arthritis, Experimental; Bone Resorption; Cancellous Bone; Female; Inflammation; Joints; Male; Mice, Knockout; Mice, Transgenic; Receptor, Angiotensin, Type 1; Tumor Necrosis Factor-alpha; X-Ray Microtomography | 2020 |
Repositioning of pentoxifylline as an immunomodulator and regulator of the renin-angiotensin system in the treatment of COVID-19.
Topics: Alveolar Epithelial Cells; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Complement Activation; COVID-19; COVID-19 Drug Treatment; Cytokines; Disease Models, Animal; Drug Repositioning; Endothelial Cells; Gene Expression Regulation; Humans; Immunologic Factors; Inflammation; Lymphocyte Subsets; Microcirculation; Oxidative Stress; Pandemics; Pentoxifylline; Rats; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2; Signal Transduction; Venous Thromboembolism | 2020 |
Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Carboxy-Lyases; China; Disease Models, Animal; Humans; Inflammation; Kelch-Like ECH-Associated Protein 1; Macrophages; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NF-E2-Related Factor 2; Succinates | 2020 |
TRIF/EGFR signalling mediates angiotensin-II-induced cardiac remodelling in mice.
Topics: Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Cardiomegaly; ErbB Receptors; Inflammation; Male; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; RNA, Messenger; Signal Transduction; Ventricular Remodeling | 2020 |
Simvastatin Attenuates Abdominal Aortic Aneurysm Formation Favoured by Lack of Nrf2 Transcriptional Activity.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Collagen; Elastin; Humans; Inflammation; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction; Simvastatin; Transcription, Genetic; Vascular Cell Adhesion Molecule-1 | 2020 |
Ex vivo magnetic particle imaging of vascular inflammation in abdominal aortic aneurysm in a murine model.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Feasibility Studies; Humans; Inflammation; Magnetic Iron Oxide Nanoparticles; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout, ApoE | 2020 |
Ubiquitin-specific protease 19 blunts pathological cardiac hypertrophy via inhibition of the TAK1-dependent pathway.
Topics: Angiotensin II; Animals; Animals, Newborn; Aortic Valve Stenosis; Cardiomegaly; CRISPR-Cas Systems; Disease Models, Animal; Endopeptidases; Fibrosis; Inflammation; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phenylephrine; Pressure; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Ubiquitin-Protein Ligases; Ventricular Remodeling | 2020 |
Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Fibrosis; Gene Deletion; Hypertension, Renal; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephritis; Proteinuria; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2020 |
Evidence that angiotensin II does not directly stimulate the MD2-TLR4 innate inflammatory pathway.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Line; Chemokine CCL2; Humans; Hypertension; Inflammation; Kidney; Lymphocyte Antigen 96; NF-kappa B; Palmitates; Rats; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Toll-Like Receptor 4 | 2021 |
Nerolidol improves cardiac function in spontaneously hypertensive rats by inhibiting cardiac inflammation and remodelling associated TLR4/ NF-κB signalling cascade.
Topics: Angiotensin II; Animals; Cell Line; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Heart Diseases; Inflammation; Male; Models, Molecular; Molecular Structure; NF-kappa B; Protein Conformation; Rats, Inbred SHR; Rats, Inbred WKY; Sesquiterpenes; Toll-Like Receptor 4 | 2021 |
ASK1 Enhances Angiotensin II-Induced Liver Fibrosis
Topics: Angiotensin II; Cell Line; Cell Survival; Coculture Techniques; Culture Media, Conditioned; Cytokines; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Exosomes; Humans; Inflammation; Liver Cirrhosis; MAP Kinase Kinase Kinase 5; Microscopy, Electron; Microscopy, Fluorescence; Reactive Oxygen Species | 2020 |
Antioxidant protein peroxiredoxin 6 suppresses the vascular inflammation, oxidative stress and endothelial dysfunction in angiotensin II-induced endotheliocyte.
Topics: Angiotensin II; Antioxidants; Cytokines; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Oxidative Stress; Peroxiredoxin VI; Reactive Oxygen Species | 2020 |
Deficit of glucocorticoid-induced leucine zipper amplifies angiotensin-induced cardiomyocyte hypertrophy and diastolic dysfunction.
Topics: Angiotensin II; Animals; Blood Pressure; Capillaries; Cell Death; Diastole; Extracellular Matrix; Fibrosis; Hypertrophy; Hypertrophy, Left Ventricular; Inflammation; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Transcription Factors | 2021 |
Ferrostatin-1 alleviates angiotensin II (Ang II)- induced inflammation and ferroptosis in astrocytes.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclohexylamines; Cytokines; Ferroptosis; Heme Oxygenase-1; Inflammation; Inflammation Mediators; Membrane Proteins; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phenylenediamines; Reactive Oxygen Species; Signal Transduction | 2021 |
Mep1a contributes to Ang II-induced cardiac remodeling by promoting cardiac hypertrophy, fibrosis and inflammation.
Topics: Angiotensin II; Animals; Cardiomegaly; Cytokines; Fibrosis; Inflammation; Macrophages; Male; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; Ventricular Remodeling | 2021 |
Myeloid differentiation protein 2 mediates angiotensin II-induced inflammation and mesenchymal transition in vascular endothelium.
Topics: Angiotensin II; Animals; Aorta; Endothelium, Vascular; Epithelial-Mesenchymal Transition; Inflammation; Lymphocyte Antigen 96; Male; Mice, Inbred C57BL | 2021 |
High NOR-1 (Neuron-Derived Orphan Receptor 1) Expression Strengthens the Vascular Wall Response to Angiotensin II Leading to Aneurysm Formation in Mice.
Topics: Aneurysm; Angiotensin II; Animals; Disease Models, Animal; DNA-Binding Proteins; Elastin; Inflammation; Matrix Metalloproteinases; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Oxidative Stress; Receptors, Steroid; Receptors, Thyroid Hormone; Signal Transduction | 2021 |
Effects of DA-9801 on the inflammation and apoptosis induced by angiotensin II in human dermal microvascular endothelial cells.
Topics: Angiotensin II; Apoptosis; Cells, Cultured; Dermis; Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; NADPH Oxidases; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Plant Preparations; Reactive Oxygen Species | 2021 |
The Histamine 3 Receptor Is Expressed in the Heart and Its Activation Opposes Adverse Cardiac Remodeling in the Angiotensin II Mouse Model.
Topics: Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Inflammation; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Ventricular Remodeling | 2020 |
The assessment of serum ACE activity in COVID-19 and its association with clinical features and severity of the disease.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Biomarkers; Comorbidity; COVID-19; Female; Humans; Inflammation; Male; Middle Aged; Peptidyl-Dipeptidase A; SARS-CoV-2; Severity of Illness Index | 2021 |
Myeloid differentiation 2 deficiency attenuates AngII-induced arterial vascular oxidative stress, inflammation, and remodeling.
Topics: Angiotensin II; Animals; Aorta; Gene Knockdown Techniques; Humans; In Vitro Techniques; Inflammation; Lymphocyte Antigen 96; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Reactive Oxygen Species; Vascular Remodeling; Vasoconstrictor Agents | 2021 |
Endothelial NADPH oxidase 4 protects against angiotensin II-induced cardiac fibrosis and inflammation.
Topics: Angiotensin II; Animals; Endothelial Cells; Fibrosis; Inflammation; Mice; Mice, Transgenic; Myocardium; NADPH Oxidase 4 | 2021 |
Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway.
Topics: ADAM10 Protein; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Calcium Chloride; Cell Movement; Chromones; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Morpholines; Neuropeptides; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Hormones; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Notch1; Transcription Factor HES-1 | 2021 |
Exosomes Derived From Hypertrophic Cardiomyocytes Induce Inflammation in Macrophages
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cell Communication; Cellular Microenvironment; Exosomes; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Interleukin-8; Macrophages; Mice; MicroRNAs; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Phosphorylation; Rats, Wistar; RAW 264.7 Cells; Signal Transduction | 2020 |
Toll-like receptor 2 signaling deficiency in cardiac cells ameliorates Ang II-induced cardiac inflammation and remodeling.
Topics: Angiotensin II; Animals; Bone Marrow Transplantation; Cell Line; Gene Knockdown Techniques; Hypertension; Immunity, Innate; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; Myocardium; Myocytes, Cardiac; Rats; Signal Transduction; Toll-Like Receptor 2; Translational Research, Biomedical; Vascular Remodeling | 2021 |
MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Trans-Activators | 2021 |
Activated Factor X Signaling Pathway via Protease-Activated Receptor 2 Is a Novel Therapeutic Target for Preventing Atrial Fibrillation.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Factor Xa; Inflammation; Mice; Rats; Receptor, PAR-2; Rivaroxaban; Signal Transduction; Warfarin | 2021 |
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Histone Demethylases; Inflammation; Inflammation Mediators; Jumonji Domain-Containing Histone Demethylases; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Up-Regulation | 2021 |
Protective effects of 4-octyl itaconate against inflammatory response in angiotensin II-induced oxidative stress in human primary retinal pigment epithelium.
Topics: Angiotensin II; Cytokines; Humans; Inflammation; Oxidative Stress; Primary Cell Culture; Retinal Pigment Epithelium; RNA, Long Noncoding; RNA, Messenger; Signal Transduction; Succinates; Vasoconstrictor Agents | 2021 |
Adventitial recruitment of Lyve-1- macrophages drives aortic aneurysm in an angiotensin-2-based murine model.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Inflammation Mediators; Macrophages; Membrane Transport Proteins; Mice; Signal Transduction | 2021 |
Direct comparison of inorganic nitrite and nitrate on vascular dysfunction and oxidative damage in experimental arterial hypertension.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitrites; Oxidative Stress | 2021 |
Lp-PLA2 inhibition prevents Ang II-induced cardiac inflammation and fibrosis by blocking macrophage NLRP3 inflammasome activation.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Angiotensin II; Animals; Anti-Inflammatory Agents; Benzaldehydes; Cardiomegaly; Cardiotonic Agents; Enzyme Inhibitors; Fibrosis; Heart; Inflammasomes; Inflammation; Macrophages; Male; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Oximes | 2021 |
Sinigrin attenuates angiotensin II‑induced kidney injury by inactivating nuclear factor‑κB and extracellular signal‑regulated kinase signaling
Topics: Angiotensin II; Animals; Cell Line; Chemokine CCL2; Creatinine; Gene Expression Regulation; Glucosinolates; Humans; Inflammation; Kidney; Kidney Diseases; Malondialdehyde; MAP Kinase Signaling System; NF-kappa B; Oxidative Stress; Rats, Inbred SHR; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2021 |
Fibroblast-specific IKK-β deficiency ameliorates angiotensin II-induced adverse cardiac remodeling in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Fibrosis; Gene Knockdown Techniques; Heart Rate; Hypertension; I-kappa B Kinase; Inflammation; Macrophages; Male; Mice; Myocarditis; Myocardium; Organ Size; Protective Factors; Signal Transduction; Ventricular Remodeling | 2021 |
EHP-101 alleviates angiotensin II-induced fibrosis and inflammation in mice.
Topics: Administration, Oral; Angiotensin II; Animals; Anti-Inflammatory Agents; Cannabidiol; Fibroblasts; Fibrosis; Gene Expression Regulation; Inflammation; Losartan; Male; Mice; Mice, Inbred C57BL; Myocardium; Myofibroblasts | 2021 |
Resolvin-D1 attenuation of angiotensin II-induced cardiac inflammation in mice is associated with prevention of cardiac remodeling and hypertension.
Topics: Angiotensin II; Animals; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Docosahexaenoic Acids; Gene Expression Regulation; Humans; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Mice; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Ventricular Remodeling | 2021 |
Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21-ACE2 signaling.
Topics: Adventitia; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta; Apoptosis; Cell Movement; Fibroblast Growth Factors; Fibroblasts; Inflammation; Male; Models, Biological; Oxidative Stress; Peptide Hormones; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Comparative beneficial effects of nebivolol and nebivolol/valsartan combination against mitochondrial dysfunction in angiotensin II-induced pathology in H9c2 cardiomyoblasts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Cell Culture Techniques; Drug Combinations; Heart; Hypertension; Inflammation; Mechanistic Target of Rapamycin Complex 1; Mitochondria; Myoblasts, Cardiac; Myocardium; Nebivolol; Organelle Biogenesis; Oxidative Stress; Rats; Reactive Oxygen Species; Valsartan | 2021 |
Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Angiotensin II; Animals; Behavior, Animal; Blood Pressure; Brain; Cognition; Disease Models, Animal; Hippocampus; Inflammation; Infusions, Intraventricular; Male; Mice; Mice, Transgenic; Muscle, Skeletal; Muscular Atrophy; Oxidative Stress; Sarcopenia; Vasoconstrictor Agents | 2017 |
[Irbesartan ameliorates cardiac inflammation in type 2 diabetic db/db mice].
Topics: Actins; Angiotensin II; Animals; Biphenyl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Inflammation; Interleukin-6; Irbesartan; Mice; Obesity; Random Allocation; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetrazoles; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2016 |
Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Mice; Mice, Transgenic; Myocardium; Protein-Lysine 6-Oxidase; Signal Transduction; Ventricular Remodeling | 2017 |
Ophiopogonin D and EETs ameliorate Ang II-induced inflammatory responses via activating PPARα in HUVECs.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; NF-kappa B; PPAR alpha; Protein Transport; Saponins; Spirostans | 2017 |
Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress.
Topics: Aging; Angiotensin II; Animals; Biomarkers; Blood Pressure; Brain; Gene Expression Regulation; Inflammation; Kidney; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Oxidative Stress; Vasoconstriction | 2017 |
Effect of uric acid on inflammatory COX-2 and ROS pathways in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Disease Models, Animal; Humans; Hypertension; Inflammation; Losartan; Muscle, Smooth, Vascular; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; Receptor Protein-Tyrosine Kinases; Signal Transduction; Superoxides; Uric Acid | 2017 |
Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response.
Topics: Angiotensin II; Animals; Cell Line, Tumor; Cytokines; Diabetes Mellitus, Type 2; eIF-2 Kinase; Endoplasmic Reticulum Stress; Endoribonucleases; Gene Expression; Gene Knockdown Techniques; Glucose; Inflammation; Inositol 1,4,5-Trisphosphate Receptors; Insulin-Secreting Cells; Insulinoma; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Renin-Angiotensin System; RNA, Small Interfering; Taurine; Ursodeoxycholic Acid | 2017 |
Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II-Induced Cardiac Diastolic Dysfunction in Male Mice.
Topics: Adamantane; Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; CD4-Positive T-Lymphocytes; CD8 Antigens; Diastole; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Echocardiography; Fibrosis; Gene Expression; Heart; Inflammation; Interleukin-17; Interleukin-18; Lymphocytes; Macrophages; Male; Mice; Proto-Oncogene Proteins c-jun; Signal Transduction; Vascular Stiffness; Vasoconstrictor Agents | 2017 |
The SGK1 inhibitor EMD638683, prevents Angiotensin II-induced cardiac inflammation and fibrosis by blocking NLRP3 inflammasome activation.
Topics: Angiotensin II; Animals; Benzamides; Cardiotonic Agents; Cells, Cultured; Cytoprotection; Fibrosis; Heart; Hydrazines; Inflammasomes; Inflammation; Mice; Mice, Inbred C57BL; Myocarditis; Myocardium; NLR Family, Pyrin Domain-Containing 3 Protein | 2018 |
Differential Expression of Hypertensive Phenotypes in BXD Mouse Strains in Response to Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Fibrosis; Heart Diseases; Hypertension; Inflammation; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Phenotype; Species Specificity; Transforming Growth Factor beta; Vasoconstrictor Agents | 2017 |
Beyond the matrix: MMP2 as critical regulator of inflammation-mediated vascular dysfunction.
Topics: Angiotensin II; Humans; Inflammation; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Vascular System Injuries | 2017 |
Deletion of protein kinase B2 preserves cardiac function by blocking interleukin-6-mediated injury and restores blood pressure during angiotensin II/high-salt-diet-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Movement; Chemokine CCL2; Fibrosis; Gene Expression; Hypertension; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-akt; Sodium Chloride, Dietary; Stroke Volume; Vasoconstrictor Agents; Ventricular Function, Left | 2018 |
Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis.
Topics: Angiotensin II; Animals; Atherosclerosis; Disease Models, Animal; Inflammation; Leukocytes; Mice; Mice, Knockout; Receptors, LDL; Rho Guanine Nucleotide Exchange Factors; Vasculitis | 2017 |
Angiotensin-converting enzyme 2-angiotensin (1-7)-Mas axis prevents pancreatic acinar cell inflammatory response via inhibition of the p38 mitogen-activated protein kinase/nuclear factor-κB pathway.
Topics: Acinar Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Imidazoles; Inflammation; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pancreas; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
DKK3 overexpression attenuates cardiac hypertrophy and fibrosis in an angiotensin-perfused animal model by regulating the ADAM17/ACE2 and GSK-3β/β-catenin pathways.
Topics: ADAM17 Protein; Adaptor Proteins, Signal Transducing; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Apoptosis; beta Catenin; Cardiomegaly; Cell Proliferation; Disease Models, Animal; Fibroblasts; Fibrosis; Glycogen Synthase Kinase 3 beta; Inflammation; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinases; Mice, Inbred C57BL; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Phosphorylation; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2018 |
Temporal changes in cardiac oxidative stress, inflammation and remodeling induced by exercise in hypertension: Role for local angiotensin II reduction.
Topics: Angiotensin II; Animals; Hypertension; Inflammation; Male; Myocardium; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Ventricular Remodeling | 2017 |
Angiotensin 1-7 ameliorates caerulein-induced inflammation in pancreatic acinar cells by downregulating Toll-like receptor 4/nuclear factor-κB expression.
Topics: Acinar Cells; Angiotensin I; Angiotensin II; Animals; Cell Line; Ceruletide; Down-Regulation; Inflammation; Interleukin-10; Interleukin-6; Microscopy, Fluorescence; NF-kappa B; Peptide Fragments; Rats; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
CX3CL1/CX3CR1 Axis Contributes to Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation and Inflammatory Cytokine Production.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Cytokines; Inflammation; Mice; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species | 2018 |
Myeloid CD11c
Topics: Angiotensin II; Animals; Antigen-Presenting Cells; Blood Pressure; CD11c Antigen; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Inflammation; Ion Transport; Mice; Mice, Transgenic; Myeloid Cells; Sodium Chloride, Dietary | 2018 |
A critical role for both CD40 and VLA5 in angiotensin II-mediated thrombosis and inflammation.
Topics: Angiotensin II; Animals; CD40 Antigens; CD40 Ligand; Humans; Inflammation; Integrin alpha5beta1; Male; Mice; Mice, Knockout; Signal Transduction; Thrombosis | 2018 |
Inhibition of miR-155 attenuates abdominal aortic aneurysm in mice by regulating macrophage-mediated inflammation.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Movement; Cell Proliferation; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; MicroRNAs; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type II | 2018 |
Differential effect of angiotensin II and blood pressure on hippocampal inflammation in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Hippocampus; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Random Allocation | 2018 |
Cucumis sativus Aqueous Fraction Inhibits Angiotensin II-Induced Inflammation and Oxidative Stress In Vitro.
Topics: Amino Acids; Angiotensin II; Anti-Inflammatory Agents; Antioxidants; Cell Adhesion Molecules; Cell Line; Cucumis sativus; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Nitric Oxide; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Reactive Oxygen Species | 2018 |
The immunoproteasome subunit LMP10 mediates angiotensin II-induced retinopathy in mice.
Topics: Angiotensin II; Animals; Female; Humans; Hypertensive Retinopathy; I-kappa B Kinase; Inflammation; Male; Mice; Mice, Knockout; Oxidative Stress; Phosphorylation; Proteasome Endopeptidase Complex; Reactive Oxygen Species; Signal Transduction | 2018 |
Mercaptoethanol Protects the Aorta from Dissection by Inhibiting Oxidative Stress, Inflammation, and Extracellular Matrix Degeneration in a Mouse Model.
Topics: Angiotensin II; Animals; Aorta; Aortic Dissection; Disease Models, Animal; Extracellular Matrix; Glutamate-Cysteine Ligase; Inflammation; Inflammation Mediators; Interleukin-1beta; Male; Mercaptoethanol; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Signal Transduction; Superoxide Dismutase-1; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2018 |
Angiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats.
Topics: Angiotensin II; Animals; Heart Failure; Inflammation; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Subfornical Organ | 2018 |
Red alga polysaccharides attenuate angiotensin II-induced inflammation in coronary endothelial cells.
Topics: Angiotensin II; Anti-Inflammatory Agents; Antioxidant Response Elements; Cell Line; Endothelial Cells; Gene Expression Regulation; Genes, Reporter; Humans; I-kappa B Proteins; Inflammation; Intercellular Adhesion Molecule-1; Kelch-Like ECH-Associated Protein 1; Luciferases; Models, Biological; NF-E2-Related Factor 2; NF-kappa B; Polysaccharides; Rhodophyta; Signal Transduction; Superoxide Dismutase; Vascular Cell Adhesion Molecule-1 | 2018 |
Angiotensin II enhances the acetylation and release of HMGB1 in RAW264.7 macrophage.
Topics: Acetylation; Angiotensin II; Animals; Cell Polarity; Cytokines; HMGB1 Protein; Inflammation; Macrophages, Peritoneal; Mice; Protein Transport; RAW 264.7 Cells; Signal Transduction; Sirtuin 1 | 2018 |
Aliskiren: Preclinical evidence for the treatment of hyperproliferative skin disorders.
Topics: Amides; Angiotensin II; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Cardiovascular System; Disease Models, Animal; Female; Fumarates; Inflammation; Keratinocytes; Mice; Psoriasis; Renin; Renin-Angiotensin System; Skin Diseases | 2018 |
Astragaloside IV protects against the pathological cardiac hypertrophy in mice.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cardiotonic Agents; Enzyme Activation; Inflammation; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Phosphorylation; Pressure; Protein Serine-Threonine Kinases; Saponins; Signal Transduction; Triterpenes | 2018 |
CaMKIIδ-mediated inflammatory gene expression and inflammasome activation in cardiomyocytes initiate inflammation and induce fibrosis.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Chemokine CCL2; Chemokines; Cytokines; Fibrosis; Gene Deletion; Gene Expression; Inflammasomes; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Cells; Myocytes, Cardiac; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; RNA, Messenger; Signal Transduction | 2018 |
Evidence That ADAM17 Mediates the Protective Action of CGRP against Angiotensin II-Induced Inflammation in Vascular Smooth Muscle Cells.
Topics: ADAM17 Protein; Angiotensin II; Animals; Calcitonin Gene-Related Peptide; Cell Line; ErbB Receptors; Inflammation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Renin-Angiotensin System; RNA, Small Interfering | 2018 |
Recombinant leptin attenuates abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Inflammation; Injections, Intraperitoneal; Leptin; Mice; Mice, Inbred C57BL; Mice, Knockout; Recombinant Proteins; T-Lymphocytes; Th1 Cells | 2018 |
PPARγ agonist rosiglitazone alters the temporal and spatial distribution of inflammation during abdominal aortic aneurysm formation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Disease Models, Animal; Inflammation; Male; Mice; Mice, Knockout; Models, Biological; PPAR gamma; Rosiglitazone; Th2 Cells; Thiazolidinediones; Vasodilator Agents | 2018 |
Nigella sativa extract is a potent therapeutic agent for renal inflammation, apoptosis, and oxidative stress in a rat model of unilateral ureteral obstruction.
Topics: Angiotensin II; Animals; Apoptosis; Captopril; Chemokine CCL2; Creatinine; Fibrosis; Inflammation; Kidney; Kidney Diseases; Losartan; Male; Malondialdehyde; Nigella sativa; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Urea; Ureteral Obstruction | 2018 |
AT2R Activation Prevents Microglia Pro-inflammatory Activation in a NOX-Dependent Manner: Inhibition of PKC Activation and p47
Topics: Angiotensin II; Animals; Cell Line; Glycogen Synthase Kinase 3 beta; Inflammation; Lipopolysaccharides; Mice; Microglia; Mitochondria; NADPH Oxidases; Neurons; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Kinase C; Protein Phosphatase 2; Proteolysis; Reactive Oxygen Species; Receptor, Angiotensin, Type 2; Tetradecanoylphorbol Acetate | 2019 |
The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease.
Topics: Amino Acid Substitution; Angiotensin II; Animals; Catalytic Domain; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epithelial Sodium Channels; Inflammation; Interleukin-1beta; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis, Site-Directed; Natriuresis; Oligopeptides; Peptidyl-Dipeptidase A; Protein Domains; Renin-Angiotensin System | 2018 |
Protein Arginine Methyltransferase 2 Inhibits Angiotensin II-Induced Proliferation and Inflammation in Vascular Smooth Muscle Cells.
Topics: Angiotensin II; Cell Proliferation; Cells, Cultured; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein-Arginine N-Methyltransferases | 2018 |
No energy wasted in the fight against vascular inflammation.
Topics: Angiotensin II; Humans; Inflammation; Phenotype | 2018 |
Inhibitory effects of cycloastragenol on abdominal aortic aneurysm and its related mechanisms.
Topics: Administration, Oral; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Conformation; Oxidative Stress; Pancreatic Elastase; Rats; Rats, Sprague-Dawley; Sapogenins; Signal Transduction | 2019 |
Isoliquiritigenin alleviated the Ang II-induced hypertensive renal injury through suppressing inflammation cytokines and oxidative stress-induced apoptosis via Nrf2 and NF-κB pathways.
Topics: Angiotensin II; Apoptosis; Cell Cycle Checkpoints; Cell Line; Cell Survival; Chalcones; Cytokines; Extracellular Matrix; Humans; Hypertension, Renal; Inflammation; Kidney; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress | 2018 |
von Willebrand factor deficiency does not influence angiotensin II-induced abdominal aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Vasoconstrictor Agents; von Willebrand Factor | 2018 |
Th1-type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II-dependent hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; Antigens, Bacterial; Dose-Response Relationship, Drug; Flow Cytometry; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Porphyromonas gingivalis; Th1 Cells; Ventricular Dysfunction | 2019 |
Genistein inhibits Ang II-induced CRP and MMP-9 generations via the ER-p38/ERK1/2-PPARγ-NF-κB signaling pathway in rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Atherosclerosis; C-Reactive Protein; Cells, Cultured; Dose-Response Relationship, Drug; Genistein; Inflammation; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; PPAR gamma; Rats; Rats, Sprague-Dawley; Time Factors | 2019 |
Gambogic acid prevents angiotensin II‑induced abdominal aortic aneurysm through inflammatory and oxidative stress dependent targeting the PI3K/Akt/mTOR and NF‑κB signaling pathways.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Garcinia; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Xanthones | 2019 |
K
Topics: Angiotensin II; Animals; Blotting, Western; Cardiomyopathies; Fibroblasts; Fibrosis; Gene Expression Regulation; Heart Ventricles; Immunohistochemistry; Inflammation; Intermediate-Conductance Calcium-Activated Potassium Channels; Male; Monocytes; Myocardium; Myofibroblasts; Rats; Rats, Sprague-Dawley; RNA | 2019 |
Vascular Smooth Muscle Cell Remodeling.
Topics: Angiotensin II; Cell Proliferation; Humans; Inflammation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; RNA, Long Noncoding | 2018 |
1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Humans; Hydrolyzable Tannins; Hypertension; Inflammation; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Oenothera; Tumor Cells, Cultured; Ventricular Dysfunction | 2019 |
Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation.
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Inflammation; Interleukin-6; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; NF-E2-Related Factor 2; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor | 2019 |
Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction.
Topics: Adult; Angiotensin II; Cell Communication; Cell Line; Chemokine CX3CL1; Cytokines; Female; Gene Expression Profiling; Gene Expression Regulation; Gestational Age; Humans; Inflammation; Male; Monocytes; Placenta; Pregnancy; RNA, Messenger; Transcriptome; Trophoblasts; Young Adult | 2019 |
Knockdown of lncRNA
Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Disease Models, Animal; Extracellular Matrix; Gene Knockdown Techniques; Humans; Inflammation; Mice; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; RNA, Small Interfering | 2019 |
Transactivation domain of Krüppel-like factor 15 negatively regulates angiotensin II-induced adventitial inflammation and fibrosis.
Topics: Adventitia; Angiotensin II; Animals; Cell Movement; Cells, Cultured; Chemokine CCL2; Collagen; Fibroblasts; Fibrosis; HEK293 Cells; Humans; Inflammation; Kruppel-Like Transcription Factors; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Protein Domains; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Smad Proteins; Vascular Cell Adhesion Molecule-1 | 2019 |
Class I histone deacetylase inhibitor MS-275 attenuates vasoconstriction and inflammation in angiotensin II-induced hypertension.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta; Benzamides; Blood Pressure; Cell Adhesion Molecules; Histone Deacetylase Inhibitors; Hypertension; Inflammation; Macrophages; Male; Mice; Myocytes, Smooth Muscle; NADPH Oxidase 1; Nitric Oxide; Pyridines; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Up-Regulation; Vasoconstriction | 2019 |
Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction.
Topics: Aging; Angiotensin II; Animals; Antigens, Differentiation; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Calcium-Binding Proteins; Cognitive Dysfunction; Disease Models, Animal; Genes, MHC Class II; Hippocampus; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia | 2019 |
ATG5-mediated autophagy suppresses NF-κB signaling to limit epithelial inflammatory response to kidney injury.
Topics: Angiotensin II; Animals; Autophagy; Autophagy-Related Protein 5; Cells, Cultured; Cytokines; Disease Models, Animal; Fibrosis; G2 Phase Cell Cycle Checkpoints; HEK293 Cells; Humans; Inflammation; Kidney; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Signal Transduction; Ureteral Obstruction | 2019 |
Rivaroxaban, a Direct Factor Xa Inhibitor, Ameliorates Hypertensive Renal Damage Through Inhibition of the Inflammatory Response Mediated by Protease-Activated Receptor Pathway.
Topics: Albuminuria; Angiotensin II; Animals; Blood Coagulation; Factor Xa Inhibitors; Gene Knockdown Techniques; Glomerular Basement Membrane; Glomerular Mesangium; Humans; Hypertension; In Vitro Techniques; Inflammation; Kidney Glomerulus; Male; Mice; Mice, Transgenic; Podocytes; Receptor, PAR-2; Renal Insufficiency, Chronic; Renin; Reverse Transcriptase Polymerase Chain Reaction; Rivaroxaban; Vasoconstrictor Agents | 2019 |
LncRNA H19 promotes vascular inflammation and abdominal aortic aneurysm formation by functioning as a competing endogenous RNA.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; Signal Transduction; Transcription, Genetic; Up-Regulation | 2019 |
Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice.
Topics: Angiotensin II; Animals; Drugs, Chinese Herbal; Fibrosis; Ghrelin; Inflammation; Kidney Diseases; Mice; Treatment Outcome | 2019 |
Testosterone inhibits aneurysm formation and vascular inflammation in male mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Flutamide; Inflammation; Interleukin-1beta; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Androgen; Testosterone | 2019 |
T-Lymphocyte-Based Renin Angiotensin System in Obesity.
Topics: Adult; Aged; Angiotensin II; Body Mass Index; Case-Control Studies; Cells, Cultured; Female; Gene Expression; Humans; Inflammation; Male; Middle Aged; Obesity; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; T-Lymphocytes | 2019 |
Mixed Vehicle Emissions Induces Angiotensin II and Cerebral Microvascular Angiotensin Receptor Expression in C57Bl/6 Mice and Promotes Alterations in Integrity in a Blood-Brain Barrier Coculture Model.
Topics: Air Pollutants; Angiotensin II; Animals; Astrocytes; Blood-Brain Barrier; Central Nervous System; Cerebrovascular Circulation; Coculture Techniques; Diet, High-Fat; Gene Expression; Inflammation; Inhalation Exposure; Male; Mice; Mice, Inbred C57BL; Microvessels; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tight Junction Proteins; Vehicle Emissions | 2019 |
Schizandrin B attenuates angiotensin II induced endothelial to mesenchymal transition in vascular endothelium by suppressing NF-κB activation.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclooctanes; Cytokines; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Gene Expression Regulation; Inflammation; Lignans; Male; Mice; Mice, Inbred C57BL; NF-kappa B p50 Subunit; Oxidative Stress; Phenotype; Polycyclic Compounds; Signal Transduction; Vascular Remodeling | 2019 |
Elevated bone marrow sympathetic drive precedes systemic inflammation in angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Bone Marrow; CD4-Positive T-Lymphocytes; Disease Models, Animal; Femur; Hypertension; Inflammation; Male; Microglia; Neuroimmunomodulation; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors | 2019 |
High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension.
Topics: Adolescent; Adoptive Transfer; Adult; Angiotensin II; Animals; Aorta; Bacteria; Blood Pressure; CD11c Antigen; Colon; Cytokines; Dendritic Cells; Disease Models, Animal; Dysbiosis; Female; Gastrointestinal Microbiome; Humans; Hypertension; Inflammation; Lipids; Lymph Nodes; Male; Mice; Mice, Inbred C57BL; Middle Aged; Myeloid Cells; Peyer's Patches; RNA, Ribosomal, 16S; Sodium Chloride; Sodium Chloride, Dietary; Young Adult | 2019 |
Angiotensin II Increases Endoplasmic Reticulum Stress in Adipose Tissue and Adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Angiotensin II; Animals; Captopril; Diet; Endoplasmic Reticulum Stress; Humans; Inflammation; Mice; Mice, Transgenic; MicroRNAs; NF-kappa B; Renin-Angiotensin System; YY1 Transcription Factor | 2019 |
The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice.
Topics: Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Cytokines; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Endothelial Cells; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Inflammation; Male; Malondialdehyde; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phytotherapy; Superoxide Dismutase; Vascular Remodeling | 2019 |
TSLP promote M2 macrophages polarization and cardiac healing after myocardial infarction.
Topics: Angiotensin II; Animals; Cell Polarity; Cytokines; Female; Heart Function Tests; Inflammation; Macrophage Activation; Macrophages; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Phenotype; Thymic Stromal Lymphopoietin; Wound Healing | 2019 |
Podoplanin neutralization improves cardiac remodeling and function after acute myocardial infarction.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Cardiomyopathies; Cell Survival; Cicatrix; Echocardiography; Fibrosis; Heart Failure; Heart Transplantation; Hemodynamics; Humans; Hypertrophy, Left Ventricular; Inflammation; Macrophages; Membrane Glycoproteins; Mice; Monocytes; Myocardial Infarction; Myocardial Ischemia; Myocytes, Cardiac; Regeneration; Vasoconstrictor Agents; Ventricular Function, Left; Ventricular Remodeling | 2019 |
Angiopoietin-Like 7 Contributes to Angiotensin II-Induced Proliferation, Inflammation and Apoptosis in Vascular Smooth Muscle Cells.
Topics: Angiopoietin-Like Protein 7; Angiopoietin-like Proteins; Angiotensin II; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Down-Regulation; Humans; Hypertension; Inflammation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Small Interfering | 2019 |
PD123319, angiotensin II type II receptor antagonist, inhibits oxidative stress and inflammation in 2, 4-dinitrobenzene sulfonic acid-induced colitis in rat and ameliorates colonic contractility.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Colitis; Colon; Dinitrobenzenes; Imidazoles; Inflammation; Male; Oxidative Stress; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2 | 2020 |
White blood cell count in women: relation to inflammatory biomarkers, haematological profiles, visceral adiposity, and other cardiovascular risk factors.
Topics: Adipose Tissue; Adult; Angiotensin II; Biomarkers; Blood Platelets; Body Composition; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Female; Humans; Inflammation; Interleukin-6; Intra-Abdominal Fat; Leukocyte Count; Lipids; Obesity; Population Surveillance; Risk Factors; Waist Circumference | 2013 |
Effect of renal sympathetic denervation on atrial substrate remodeling in ambulatory canines with prolonged atrial pacing.
Topics: Aldosterone; Angiotensin II; Animals; Apoptosis; Atrial Fibrillation; Atrial Natriuretic Factor; Atrial Remodeling; Blood Pressure; Cardiac Pacing, Artificial; Dogs; Fibrosis; Gap Junctions; GAP-43 Protein; Heart Atria; Inflammation; Interleukin-6; Kidney; Myocytes, Cardiac; Sympathectomy; Tumor Necrosis Factor-alpha | 2013 |
Long-term effects of early overnutrition in the heart of male adult rats: role of the renin-angiotensin system.
Topics: Aging; Angiotensin II; Animals; Apoptosis; Biomarkers; Bradykinin; Feeding Behavior; Gene Expression Regulation; Heart; Hemodynamics; In Vitro Techniques; Inflammation; Leptin; Male; Myocardium; Organ Size; Overnutrition; Perfusion; Rats, Sprague-Dawley; Renin-Angiotensin System; Time Factors; Vasoconstriction; Vasodilation | 2014 |
Role for granulocyte colony stimulating factor in angiotensin II-induced neutrophil recruitment and cardiac fibrosis in mice.
Topics: Angiotensin II; Animals; Antibodies; Blood Pressure; Cytokines; Fibrosis; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Granulocyte Colony-Stimulating Factor; Inflammation; Malondialdehyde; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocardium; Neutrophil Infiltration; Proto-Oncogene Proteins c-akt; STAT3 Transcription Factor | 2013 |
Development of abdominal aortic aneurysm is decreased in mice with plasma phospholipid transfer protein deficiency.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; CD4-Positive T-Lymphocytes; Cytokines; Elastin; Inflammation; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phospholipid Transfer Proteins | 2013 |
N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats.
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Body Weight; Cardiomegaly; CD4-Positive T-Lymphocytes; Collagen; Extracellular Matrix; Hypertension; Inflammation; Lung; Male; NF-kappa B; Oligopeptides; Organ Size; Protein-Lysine 6-Oxidase; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Influence and pathophysiological mechanisms of simvastatin on prostatic hyperplasia in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Endoplasmic Reticulum; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Inflammation; Insulin-Like Growth Factor I; Interleukin-6; Male; Mitochondria; Nitric Oxide Synthase Type III; Prostatic Hyperplasia; Rats; Rats, Inbred SHR; Simvastatin | 2013 |
Physiological regulation of pro-inflammatory cytokines expression in rat cardiovascular tissues by sympathetic nervous system and angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Gene Expression Regulation; Guanethidine; Heart Ventricles; Inflammation; Interleukin-6; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2013 |
Intravenous administration of mesenchymal stem cells prevents angiotensin II-induced aortic aneurysm formation in apolipoprotein E-deficient mouse.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Bone Marrow Cells; Cytokines; Disease Progression; Elastin; Femur; Inflammation; Injections, Intravenous; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Knockout | 2013 |
Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Down-Regulation; Fibrosis; Heart; Hypertension; Inflammation; Male; Mice; Mice, Knockout; MicroRNAs; Myocardium; NF-kappa B; Signal Transduction; Smad7 Protein | 2013 |
Protective role of the endothelial isoform of nitric oxide synthase in ANG II-induced inflammatory responses in the kidney.
Topics: Angiogenesis Inducing Agents; Angiotensin II; Animals; Hypertension; Inflammation; Male; Mice; Mice, Knockout; Nephritis; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Ribonuclease, Pancreatic; Up-Regulation | 2013 |
The effect of soluble RAGE on inhibition of angiotensin II-mediated atherosclerosis in apolipoprotein E deficient mice.
Topics: Angiotensin II; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Biomarkers; Blood Pressure; Cell Adhesion Molecules; Gene Expression Regulation; Gene Knockout Techniques; Humans; Inflammation; Male; Mice; Muscle, Smooth, Vascular; Plaque, Atherosclerotic; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility | 2013 |
Amelioration of angiotensin II-induced salt-sensitive hypertension by liver-type fatty acid-binding protein in proximal tubules.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Fatty Acid-Binding Proteins; Hypertension; Inflammation; Kidney; Kidney Tubules, Proximal; Mice; Mice, Transgenic; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2013 |
Loss of ACE2 exacerbates murine renal ischemia-reperfusion injury.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Chemokine CCL2; Chemokine CXCL2; Gene Expression; Inflammation; Interleukin-1beta; Interleukin-6; Kidney; Macrophages; Male; Mice; Mice, Knockout; Neutrophil Infiltration; Neutrophils; Oxidative Stress; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Reperfusion Injury; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2013 |
Combination therapy with atorvastatin and amlodipine suppresses angiotensin II-induced aortic aneurysm formation.
Topics: Amlodipine; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Atorvastatin; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Drug Therapy, Combination; Enzyme Activation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Pyrroles; rho-Associated Kinases | 2013 |
Critical role of CXCL16 in hypertensive kidney injury and fibrosis.
Topics: Angiotensin II; Animals; Blood Pressure; Chemokine CXCL16; Chemokine CXCL6; Cytokines; Fibrosis; Hypertension, Renal; Inflammation; Kidney; Macrophages; Mice; Mice, Knockout; Myofibroblasts; Nephritis; NF-kappa B; T-Lymphocytes | 2013 |
CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction.
Topics: Angiotensin II; Animals; Aorta; Blotting, Western; CD40 Ligand; Endothelial Cells; Flow Cytometry; Immunohistochemistry; Inflammation; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Platelet Activation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Thrombosis; Vascular Diseases | 2013 |
Visfatin as a novel mediator released by inflamed human endothelial cells.
Topics: Angiotensin II; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Interleukin-1beta; Nicotinamide Phosphoribosyltransferase; RNA, Messenger; Tumor Necrosis Factor-alpha | 2013 |
Aliskiren attenuates steatohepatitis and increases turnover of hepatic fat in mice fed with a methionine and choline deficient diet.
Topics: Amides; Angiotensin II; Animals; Blotting, Western; Choline; Diet; Fatty Liver; Fumarates; Immunoenzyme Techniques; Inflammation; Insulin; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Oxidative Stress; Real-Time Polymerase Chain Reaction; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Triglycerides | 2013 |
Inhibition of Toll-like receptor 2 reduces cardiac fibrosis by attenuating macrophage-mediated inflammation.
Topics: Angiotensin II; Animals; Cytokines; Fibrosis; Heart Diseases; Inflammation; Inflammation Mediators; Macrophage Activation; Macrophages; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Toll-Like Receptor 2 | 2014 |
DHEA inhibits vascular remodeling following arterial injury: a possible role in suppression of inflammation and oxidative stress derived from vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Cells, Cultured; Dehydroepiandrosterone; Dinoprost; Extracellular Signal-Regulated MAP Kinases; Inflammation; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; NADP; NADPH Oxidases; Neointima; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Regeneration; Superoxide Dismutase; Transcription Factor RelA; Vascular System Injuries | 2014 |
Acetylation of cyclophilin A is required for its secretion and vascular cell activation.
Topics: Acetylation; Angiotensin II; Animals; Cells, Cultured; Cyclophilin A; Endothelial Cells; Inflammation; Intercellular Adhesion Molecule-1; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2014 |
Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase.
Topics: ADAM Proteins; ADAM17 Protein; Adenoviridae; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Caveolin 1; Cells, Cultured; Gene Expression Regulation; Gene Silencing; Heparin-binding EGF-like Growth Factor; Immunohistochemistry; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Smooth Muscle; Oxidative Stress; Promoter Regions, Genetic; Protein-Lysine 6-Oxidase; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA Interference; Signal Transduction | 2014 |
Preconditioning via angiotensin type 2 receptor activation improves therapeutic efficacy of bone marrow mononuclear cells for cardiac repair.
Topics: Angiotensin II; Animals; Apoptosis; Bone Marrow Cells; Cell Transplantation; Coculture Techniques; Echocardiography; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Inflammation; Leukocytes, Mononuclear; Male; Myocardial Infarction; Myocytes, Cardiac; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Stem Cell Transplantation; Tetrazoles; Valine; Valsartan; Vascular Endothelial Growth Factor A | 2013 |
Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aortic Diseases; CD4 Antigens; CD8 Antigens; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Fibroblasts; Homeodomain Proteins; Hypertension; Inflammation; Interleukin-17; Male; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Stress, Mechanical; T-Lymphocytes; Vascular Stiffness; Vasculitis; Vasoconstrictor Agents | 2014 |
Atg5 deficiency-mediated mitophagy aggravates cardiac inflammation and injury in response to angiotensin II.
Topics: Angiotensin II; Animals; Autophagy-Related Protein 5; Heart Injuries; Humans; Hypertension; Inflammation; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mitophagy; Reactive Oxygen Species | 2014 |
Adiponectin expression protects against angiotensin II-mediated inflammation and accelerated atherosclerosis.
Topics: Adiponectin; Angiotensin II; Animals; Apolipoproteins; Atherosclerosis; Blood Pressure; Cholesterol; Disease Models, Animal; Gene Expression; Hypertension; Inflammation; Liver; Macrophages; Male; Mice; Mice, Knockout; Protein Multimerization; Protein Transport; Receptors, Adiponectin; Receptors, LDL; Receptors, Scavenger | 2014 |
Molecular mechanisms associated with Angiotensin-converting enzyme-inhibitory peptide activity on vascular extracellular matrix remodeling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blood Vessels; Carotid Artery, Common; Collagen; Elastic Tissue; Extracellular Matrix; Heart Rate; Inflammation; Lactoferrin; Laminin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Peptide Fragments; Random Allocation; Rats; Rats, Inbred SHR; Transcription Factor RelA; Transforming Growth Factor beta1 | 2014 |
Modulation of angiotensin II-induced inflammatory cytokines by the Epac1-Rap1A-NHE3 pathway: implications in renal tubular pathobiology.
Topics: Angiotensin II; Animals; Cell Line; Cytokines; Dose-Response Relationship, Drug; Guanine Nucleotide Exchange Factors; Inflammation; Kidney Tubules; Male; Protein Transport; rap1 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Swine | 2014 |
ADAMTS-7 expression increases in the early stage of angiotensin II-induced renal injury in elderly mice.
Topics: ADAM Proteins; ADAMTS7 Protein; Aging; Angiotensin II; Animals; Blood Pressure; HEK293 Cells; Humans; Inflammation; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Vasoconstrictor Agents | 2013 |
Adiponectin suppresses angiotensin II-induced inflammation and cardiac fibrosis through activation of macrophage autophagy.
Topics: Adiponectin; Angiotensin II; Animals; Autophagy; Cardiomyopathies; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fibrosis; Immunohistochemistry; In Vitro Techniques; Inflammation; Macrophages; Mice; Mice, Knockout; Real-Time Polymerase Chain Reaction | 2014 |
PPARδ reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice by regulating extracellular matrix homeostasis and inflammatory responses.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Extracellular Matrix; Homeostasis; Inflammation; Infusion Pumps; Male; Mice; PPAR delta | 2014 |
S100a8/a9 released by CD11b+Gr1+ neutrophils activates cardiac fibroblasts to initiate angiotensin II-Induced cardiac inflammation and injury.
Topics: Angiotensin II; Animals; Animals, Newborn; Antibodies; Antigens, Ly; Calgranulin A; Calgranulin B; CD11b Antigen; Cells, Cultured; Cytokines; Fibroblasts; Hypertension; Immunohistochemistry; Inflammation; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Neutrophils; Oligonucleotide Array Sequence Analysis; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptor 4; Transcriptome | 2014 |
Qishenyiqi protects ligation-induced left ventricular remodeling by attenuating inflammation and fibrosis via STAT3 and NF-κB signaling pathway.
Topics: Angiotensin II; Animals; Captopril; Drugs, Chinese Herbal; Fibrosis; Heart Failure; Heart Ventricles; Hemodynamics; Inflammation; Interleukin-6; Ligation; Male; Matrix Metalloproteinases; NADPH Oxidases; NF-kappa B; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor; Ventricular Remodeling | 2014 |
Participation of AT1 and Mas receptors in the modulation of inflammatory pain.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Inflammation; Losartan; Male; Mice; Mice, Knockout; Pain; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled | 2014 |
Activation of the retinoid X receptor modulates angiotensin II-induced smooth muscle gene expression and inflammation in vascular smooth muscle cells.
Topics: Actins; Angiotensin II; Animals; Bexarotene; Calcium-Binding Proteins; Calponins; Cells, Cultured; Chemokine CCL2; Gene Expression; Inflammation; Male; MAP Kinase Signaling System; Microfilament Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Retinoid X Receptors; Signal Transduction; Tetrahydronaphthalenes | 2014 |
Inhibiting the Th17/IL-17A-related inflammatory responses with digoxin confers protection against experimental abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cardiotonic Agents; Digoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Receptor Subfamily 1, Group F, Member 3; Pancreatic Elastase; Survival Rate; Swine; Th17 Cells | 2014 |
DC isoketal-modified proteins activate T cells and promote hypertension.
Topics: Aged; Aldehydes; Angiotensin II; Animals; Antigen-Presenting Cells; B7-1 Antigen; B7-2 Antigen; Cell Proliferation; Cohort Studies; Dendritic Cells; Female; Gene Expression Regulation; Humans; Hypertension; Inflammation; Interleukin-17; Interleukin-1beta; Interleukin-23; Interleukin-6; Kidney; Lymphocyte Activation; Male; Mice; Mice, Transgenic; Middle Aged; Oxidative Stress; Oxygen; Superoxides; T-Lymphocytes | 2014 |
Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension.
Topics: Albumins; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Echocardiography; Fibrosis; Heart; Heart Rate; Hypertension; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Phenotype; Sodium Chloride, Dietary | 2015 |
Angiotensin II induces interleukin-1β-mediated islet inflammation and β-cell dysfunction independently of vasoconstrictive effects.
Topics: Angiotensin II; Animals; Apoptosis; Blood Glucose; Chemokine CCL2; Diabetes Mellitus, Type 2; Diet, High-Fat; Humans; Inflammation; Insulin; Insulin Secretion; Interleukin-1beta; Islets of Langerhans; Mice; Mitochondria; Renin-Angiotensin System; Vasoconstriction | 2015 |
Angiotensin II, via angiotensin receptor type 1/nuclear factor-κB activation, causes a synergistic effect on interleukin-1-β-induced inflammatory responses in cultured mesangial cells.
Topics: Angiotensin II; Animals; Chemokines; Inflammation; Interleukin-1beta; Kidney Glomerulus; Mesangial Cells; NF-kappa B; Phosphorylation; Primary Cell Culture; Rats; Receptor, Angiotensin, Type 1 | 2015 |
Simvastatin attenuates angiotensin II‑induced inflammation and oxidative stress in human mesangial cells.
Topics: Angiotensin II; Anticholesteremic Agents; Cell Line; Chemokine CCL2; Cyclooxygenase 2; Dinoprostone; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Mesangial Cells; NADPH Oxidases; Oxidative Stress; PPAR gamma; Protein Kinase C; Reactive Oxygen Species; RNA, Messenger; Simvastatin; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2015 |
N-3 PUFAs protect against aortic inflammation and oxidative stress in angiotensin II-infused apolipoprotein E-/- mice.
Topics: Angiotensin II; Animals; Aorta; Apolipoproteins E; Body Weight; Cholesterol; Dietary Supplements; Docosahexaenoic Acids; Fatty Acids, Omega-3; Inflammation; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Oxidative Stress; Superoxides; Triglycerides | 2014 |
Pentoxifylline alleviates hypertension in metabolic syndrome: effect on low-grade inflammation and angiotensin system.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Inflammation; Male; Metabolic Syndrome; Pentoxifylline; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Vasodilator Agents | 2015 |
A role for innate immunity in the development of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cytokines; Humans; Hypertension; Immunity, Innate; Inflammation; Interleukin-6; Mice; Muscle, Smooth, Vascular; Myeloid Differentiation Factor 88; NF-kappa B; Risk Factors; Signal Transduction; Toll-Like Receptor 4 | 2014 |
Activation of the cardiac proteasome promotes angiotension II-induced hypertrophy by down-regulation of ATRAP.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Cardiomegaly; Down-Regulation; Enzyme Activation; Fibrosis; Inflammation; Male; Mice, Inbred C57BL; Models, Biological; Myocardium; p38 Mitogen-Activated Protein Kinases; Polyubiquitin; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Proteolysis; Receptor, Angiotensin, Type 1; Signal Transduction; STAT3 Transcription Factor; Ubiquitinated Proteins | 2015 |
KS370G, a caffeamide derivative, attenuates unilateral ureteral obstruction-induced renal fibrosis by the reduction of inflammation and oxidative stress in mice.
Topics: Angiotensin II; Animals; Biomarkers; Caffeic Acids; Catalase; Cell Adhesion Molecules; Chemokines; Collagen Type I; Cytoprotection; Fibronectins; Fibrosis; Gene Expression Regulation; Inflammation; Kidney; Lipid Peroxidation; Male; Mice; Oxidative Stress; Smad3 Protein; Superoxide Dismutase; Transforming Growth Factor beta1; Ureteral Obstruction | 2015 |
Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bexarotene; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Rosuvastatin Calcium; Signal Transduction; Tetrahydronaphthalenes | 2015 |
Valsartan Attenuates Atherosclerosis via Upregulating the Th2 Immune Response in Prolonged Angiotensin II-Treated ApoE(-/-) Mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies, Monoclonal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Disease Models, Animal; Inflammation; Interleukin-5; Lipids; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; T-Lymphocyte Subsets; Th2 Cells; Valsartan | 2015 |
Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Oxidative Stress; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptor 4; Up-Regulation; Vascular Remodeling | 2015 |
ACE2 and Ang-(1-7) protect endothelial cell function and prevent early atherosclerosis by inhibiting inflammatory response.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Atherosclerosis; Cell Adhesion; Cell Movement; Chemokine CCL2; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Gene Transfer Techniques; Humans; In Vitro Techniques; Inflammation; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2015 |
New insights into the mechanisms of islet inflammation in type 2 diabetes.
Topics: Angiotensin II; Animals; Humans; Inflammation; Interleukin-1beta; Islets of Langerhans; Vasoconstriction | 2015 |
Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses.
Topics: Adipose Tissue; Aging; Angiotensin II; Animals; Body Composition; CD4-Positive T-Lymphocytes; Cytokines; Female; Glucose Intolerance; Inflammation; Insulin; Insulin Resistance; Islets of Langerhans; Male; Membrane Glycoproteins; Metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Receptor, Adenosine A1; Regional Blood Flow; Signal Transduction | 2015 |
PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis.
Topics: Angiotensin II; Animals; Apoptosis; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Endothelial Cells; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Phosphorylation; Protein Kinase C-epsilon; Protoporphyrins; RNA Interference; Signal Transduction; Time Factors; Transcription, Genetic; Transfection | 2015 |
Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway.
Topics: Angiotensin II; Animals; Cell Proliferation; China; Drugs, Chinese Herbal; Humans; Hypertension, Renal; Inflammation; Mesangial Cells; NADPH Oxidases; NF-kappa B; Phytotherapy; Polygonum; Rats, Wistar; Reactive Oxygen Species; RNA, Small Interfering; Tumor Necrosis Factor-alpha; Up-Regulation | 2015 |
Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system.
Topics: Administration, Oral; Allopurinol; Angiotensin II; Animals; Diet, High-Fat; Electrocardiography; Enzyme Inhibitors; Hemodynamics; Inflammation; Insulin Resistance; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Oxidative Stress; Rats, Wistar; Ultrasonography; Uric Acid; Xanthine Oxidase | 2015 |
Tubastatin A suppresses renal fibrosis via regulation of epigenetic histone modification and Smad3-dependent fibrotic genes.
Topics: Angiotensin II; Animals; Cells, Cultured; Collagen Type I; Epigenesis, Genetic; Fibrosis; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Indoles; Inflammation; Kidney; Male; Mice; Mice, Inbred ICR; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta | 2015 |
Thrombospondin-1 (TSP1) contributes to the development of vascular inflammation by regulating monocytic cell motility in mouse models of abdominal aortic aneurysm.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bone Marrow Transplantation; Calcium Phosphates; Cell Line; Cell Movement; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Pancreatic Elastase; Radiation Chimera; Recombinant Proteins; Thrombospondin 1; Up-Regulation | 2015 |
Protective role of oleic acid against cardiovascular insulin resistance and in the early and late cellular atherosclerotic process.
Topics: Angiotensin II; Animals; Apoptosis; Atherosclerosis; Blotting, Western; Cell Line; Cell Proliferation; Chemokine CCL2; Inflammation; Insulin Resistance; Intercellular Adhesion Molecule-1; MAP Kinase Signaling System; Mice; Muscle, Smooth, Vascular; Myocytes, Cardiac; Myocytes, Smooth Muscle; NF-kappa B; Nitric Oxide Synthase Type III; Oleic Acid; Palmitates; Palmitic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2015 |
Incomplete Restoration of Angiotensin II-Induced Renal Extracellular Matrix Deposition and Inflammation Despite Complete Functional Recovery in Rats.
Topics: Angiotensin II; Animals; Collagen; Desmin; Extracellular Matrix; Hypertension, Renal; Inflammation; Kidney; Male; Rats; Rats, Wistar | 2015 |
TRIF adaptor signaling is important in abdominal aortic aneurysm formation.
Topics: Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins; Apolipoproteins E; CD3 Complex; Elastin; Gene Expression Regulation; Humans; Inflammation; Mice; Mice, Knockout; Signal Transduction; Toll-Like Receptors | 2015 |
Bone Morphogenic Protein 4 Mediates NOX1-Dependent eNOS Uncoupling, Endothelial Dysfunction, and COX2 Induction in Type 2 Diabetes Mellitus.
Topics: Angiotensin II; Animals; Aorta; Biopterins; Blood Glucose; Bone Morphogenetic Protein 4; Carrier Proteins; Cattle; Cells, Cultured; Cholesterol; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Endothelial Cells; Endothelium, Vascular; Inflammation; Male; Mice; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide Synthase Type III; RNA, Small Interfering; Superoxides | 2015 |
Dual Activation of TRIF and MyD88 Adaptor Proteins by Angiotensin II Evokes Opposing Effects on Pressure, Cardiac Hypertrophy, and Inflammatory Gene Expression.
Topics: Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Gene Expression; Inflammation; Mice; Mice, Knockout; Myeloid Differentiation Factor 88 | 2015 |
Functional Local Renin-Angiotensin System in Human and Rat Periodontal Tissue.
Topics: Adult; Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Female; Gingiva; Humans; Inflammation; Male; Middle Aged; Peptide Fragments; Periodontitis; Periodontium; Rats, Wistar; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Young Adult | 2015 |
Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Gene Deletion; Humans; Inflammation; Kidney; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Signal Transduction; Superoxides; Tumor Necrosis Factor-alpha | 2015 |
Reciprocal regulation between sirtuin-1 and angiotensin-II in the substantia nigra: implications for aging and neurodegeneration.
Topics: Aging; Angiotensin II; Animals; Brain; Cell Line; Dopaminergic Neurons; Gene Expression Regulation; Homozygote; Humans; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Fluorescence; NADPH Oxidases; Neurodegenerative Diseases; Neuroglia; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Resveratrol; Sirtuin 1; Stilbenes; Substantia Nigra | 2015 |
Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis.
Topics: Aging; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Chemokine CCL2; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Glucagon-Like Peptide-1 Receptor; Heart; Heart Diseases; Hypertension; I-kappa B Proteins; Immunohistochemistry; Incretins; Inflammation; Interleukin-10; Liraglutide; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocardium; NF-kappa B p50 Subunit; Obesity; Oxidative Stress; Real-Time Polymerase Chain Reaction; Vasoconstrictor Agents; Vimentin | 2016 |
Downregulating p22phox ameliorates inflammatory response in Angiotensin II-induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells.
Topics: Angiotensin II; Cell Line; Chemokine CCL2; Epithelial Cells; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Interleukin-8; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Retinal Pigment Epithelium; RNA, Small Interfering; Signal Transduction | 2015 |
Cofilin1 is involved in hypertension-induced renal damage via the regulation of NF-κB in renal tubular epithelial cells.
Topics: Angiotensin II; Animals; Antioxidants; Chemokine CCL2; Cofilin 1; Creatinine; Cytoskeleton; Epithelial Cells; Gene Expression Regulation; Grape Seed Extract; Humans; Hypertension; Inflammation; Interleukin-1beta; Kidney Tubules; Male; NF-kappa B p50 Subunit; Nitrogen; Proanthocyanidins; Rats; Rats, Inbred SHR; Renal Insufficiency; RNA, Small Interfering; Urea | 2015 |
Inhibition of Proteasome Activity by Low-dose Bortezomib Attenuates Angiotensin II-induced Abdominal Aortic Aneurysm in Apo E(-/-) Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bortezomib; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Proteasome Endopeptidase Complex; Proteasome Inhibitors | 2015 |
Mir-351-5p contributes to the establishment of a pro-inflammatory environment in the H9c2 cell line by repressing PTEN expression.
Topics: Angiotensin II; Animals; Cell Line; Inflammation; MicroRNAs; PTEN Phosphohydrolase; Rats; RNA Processing, Post-Transcriptional | 2016 |
A Dipeptidyl Peptidase-4 Inhibitor but not Incretins Suppresses Abdominal Aortic Aneurysms in Angiotensin II-Infused Apolipoprotein E-Null Mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Dipeptidyl-Peptidase IV Inhibitors; Gastric Inhibitory Polypeptide; Gene Expression Regulation; Glucagon-Like Peptide 1; Incretins; Inflammation; Interleukin-1beta; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Plaque, Atherosclerotic; Tissue Inhibitor of Metalloproteinase-2 | 2016 |
Central Renin-Angiotensin System Activation and Inflammation Induced by High-Fat Diet Sensitize Angiotensin II-Elicited Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Hypertension; Inflammation; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2016 |
Differential regulation of angiotensin II-induced extracellular signal regulated kinase-1/2 and -5 in progressive glomerulonephritis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Fibrosis; Glomerular Mesangium; Glomerulonephritis; Inflammation; Mitogen-Activated Protein Kinase 3; Rats; Renin-Angiotensin System; Signal Transduction | 2016 |
Cross talk between AT1 receptors and Toll-like receptor 4 in microglia contributes to angiotensin II-derived ROS production in the hypothalamic paraventricular nucleus.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Bacterial Agents; Immunity, Innate; Inflammation; Losartan; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Microglia; Minocycline; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Toll-Like Receptor 4 | 2016 |
Interleukin-10 limits increased blood pressure and vascular RhoA/Rho-kinase signaling in angiotensin II-infused mice.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Inflammation; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; rho-Associated Kinases; Signal Transduction | 2016 |
[Angiotensin II induces expression of inflammatory mediators in vascular adventitial fibroblasts].
Topics: Adventitia; Angiotensin II; Animals; Cell Line; Chemokine CCL2; Culture Media, Conditioned; Fibroblasts; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Macrophages; Mice; P-Selectin; Rats; RAW 264.7 Cells; Up-Regulation | 2015 |
Fructus mume Ethanol Extract Prevents Inflammation and Normalizes the Septohippocampal Cholinergic System in a Rat Model of Chronic Cerebral Hypoperfusion.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Brain Ischemia; Choline O-Acetyltransferase; Cholinergic Agents; Chronic Disease; Cytokines; Disease Models, Animal; Fruit; Hippocampus; Infarction, Middle Cerebral Artery; Inflammation; Male; Mitogen-Activated Protein Kinases; Neuroglia; Plant Extracts; Prunus; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products | 2016 |
Activating transcription factor 3 SUMOylation is involved in angiotensin II-induced endothelial cell inflammation and dysfunction.
Topics: Activating Transcription Factor 3; Angiotensin II; Animals; Aorta; Endothelial Cells; Gene Expression Regulation; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Inflammation; Interleukin-6; Mice; Nitric Oxide; Receptor, Angiotensin, Type 1; SUMO-1 Protein; Sumoylation; Tetrazoles; Vasodilation | 2016 |
Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34.
Topics: Angiotensin II; Animals; Behavior, Animal; Cell Line; Cerebellum; Disease Models, Animal; DNA Damage; DNA Glycosylases; Female; Frataxin; Friedreich Ataxia; Gene Expression; Gene Expression Regulation; Gene Knockdown Techniques; Inflammation; Iron-Binding Proteins; Lipopolysaccharides; Mice; Microglia; Oxidative Stress; Phenanthrenes; Poly(ADP-ribose) Polymerases; RNA, Small Interfering | 2016 |
Leukocyte Calpain Deficiency Reduces Angiotensin II-Induced Inflammation and Atherosclerosis But Not Abdominal Aortic Aneurysms in Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Bone Marrow Transplantation; Calcium-Binding Proteins; Calpain; Cell Adhesion; Cell Movement; Cells, Cultured; Coculture Techniques; Cysteine Proteinase Inhibitors; Diet, High-Fat; Disease Models, Animal; Endothelial Cells; Genetic Predisposition to Disease; Inflammation; Leukocytes; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Phenotype; Receptors, LDL; Whole-Body Irradiation | 2016 |
Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Collagen; Disease Models, Animal; Disease Progression; Elastin; Enzyme Induction; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Severity of Illness Index; Up-Regulation | 2016 |
Leptin Mediates High-Fat Diet Sensitization of Angiotensin II-Elicited Hypertension by Upregulating the Brain Renin-Angiotensin System and Inflammation.
Topics: Angiotensin II; Animals; Blood Pressure Determination; Cytokines; Diet, High-Fat; Disease Models, Animal; Hypertension; Inflammation; Leptin; Male; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Renin-Angiotensin System; RNA, Messenger; Up-Regulation | 2016 |
Peroxisome Proliferator-Activated Receptor γ Level Contributes to Structural Integrity and Component Production of Elastic Fibers in the Aorta.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Elastin; Gene Expression Regulation; Humans; Inflammation; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Middle Aged; Muscle, Smooth, Vascular; PPAR gamma | 2016 |
Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; CD3 Complex; Chymases; Humans; Imatinib Mesylate; Inflammation; Male; Mast Cells; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Signal Transduction | 2016 |
Retinol-Binding Protein 4 Induces Cardiomyocyte Hypertrophy by Activating TLR4/MyD88 Pathway.
Topics: Adipocytes; Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Cells, Cultured; Inflammation; Losartan; Male; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Myocytes, Cardiac; Oxidative Stress; Polymerase Chain Reaction; Reactive Oxygen Species; Retinol-Binding Proteins, Plasma; Signal Transduction; Toll-Like Receptor 4 | 2016 |
TNF/Ang-II synergy is obligate for fibroinflammatory pathology, but not for changes in cardiorenal function.
Topics: Angiotensin II; Animals; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibrosis; Flow Cytometry; Heart; Heart Diseases; Inflammation; Kidney; Kidney Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Tumor Necrosis Factor, Type I; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2016 |
Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflammation via NOX4 and TLR2 pathways.
Topics: Angiotensin II; Cell Line; Gene Expression Regulation; Humans; Inflammation; Mesangial Cells; NADPH Oxidase 4; NADPH Oxidases; Orchidaceae; Oxidative Stress; Plant Extracts; Polysaccharides; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 2 | 2016 |
Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging.
Topics: 1-Methyl-4-phenylpyridinium; Age Factors; Aging; Angiotensin II; Animals; Apoptosis; Cells, Cultured; Dopaminergic Neurons; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Inflammation; Injections, Intraventricular; Insulin-Like Growth Factor I; Microglia; Neurodegenerative Diseases; Oxidative Stress; Primary Cell Culture; Rats; Receptor, Angiotensin, Type 1; Receptor, IGF Type 1; Renin-Angiotensin System; Substantia Nigra | 2016 |
Endoplasmic reticulum stress in bone marrow-derived cells prevents acute cardiac inflammation and injury in response to angiotensin II.
Topics: Angiotensin II; Animals; Apoptosis; Bone Marrow Cells; Endoplasmic Reticulum Stress; Fibrosis; Inflammation; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Neutrophils; Transcription Factor CHOP | 2016 |
Angiotensin II-Mediated Increases in Damage-Associated Molecular Patterns During Acute Mental Stress.
Topics: Adolescent; Adult; Alarmins; Angiotensin II; Black or African American; Female; Humans; Inflammation; Male; Middle Aged; Stress, Psychological | 2017 |
Neuroinflammatory mechanisms of hypertension: potential therapeutic implications.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cytokines; Humans; Hypertension; Inflammation; Lipopolysaccharides; Microglia; NF-kappa B; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Renin; Toll-Like Receptor 4 | 2016 |
Silencing of hypoxia inducible factor-1α gene attenuated angiotensin Ⅱ-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Gene Silencing; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Lentivirus; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Microcirculation; RNA Interference; RNA, Small Interfering; Signal Transduction; Time Factors; Up-Regulation | 2016 |
Age-dependent alterations to paraventricular nucleus insulin-like growth factor 1 receptor as a possible link between sympathoexcitation and inflammation.
Topics: Age Factors; Angiotensin II; Animals; Astrocytes; Inflammation; Inflammation Mediators; Male; Microglia; Organ Culture Techniques; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, IGF Type 1 | 2016 |
Modulatory Effects of Egg White Ovotransferrin-Derived Tripeptide IRW (Ile-Arg-Trp) on Vascular Smooth Muscle Cells against Angiotensin II Stimulation.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Culture Techniques; Cell Line; Cell Proliferation; Conalbumin; Egg Proteins; Egg White; Inflammation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Oxidative Stress; Rats; Renin-Angiotensin System; Superoxides | 2016 |
Angiotensin II-Induced Early and Late Inflammatory Responses Through NOXs and MAPK Pathways.
Topics: Angiotensin II; Cytokines; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; MAP Kinase Signaling System; NADPH Oxidases; Reactive Oxygen Species; Time Factors | 2017 |
Protease-Activated Receptor 1 Contributes to Angiotensin II-Induced Cardiovascular Remodeling and Inflammation.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Coronary Vessels; Fibrosis; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptor, PAR-1; Signal Transduction; Vascular Remodeling | 2017 |
Macrophage-derived exosomes induce inflammatory factors in endothelial cells under hypertensive conditions.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Endothelial Cells; Exosomes; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Macrophages; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Wistar | 2017 |
Role of angiotensin II and angiotensin type-1 receptor in scorpion venom-induced cardiac and aortic tissue inflammation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Catalase; Creatine Kinase, MB Form; Cytokines; Eosinophils; Glutathione; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred Strains; Myocardium; Neutrophils; Oxidation-Reduction; Oxidative Stress; Receptor, Angiotensin, Type 1; Scorpion Venoms; Valsartan | 2017 |
Endothelin Receptor Down-Regulation Mediated Ligand Regulation Mechanisms Protect Against Cellular Hypoxia Injury in Rat Vascular Endothelial Cells.
Topics: Angiotensin II; Animals; Cell Hypoxia; Coculture Techniques; Down-Regulation; Endothelial Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interferon-gamma; Interleukin-6; Kidney; Ligands; Male; Models, Biological; NF-kappa B; NG-Nitroarginine Methyl Ester; Protective Agents; Rats, Sprague-Dawley; Receptor, Endothelin A; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Smad3 Protein; Transfection; Tumor Necrosis Factor-alpha | 2016 |
Endoplasmic reticulum stress inhibition attenuates hypertensive chronic kidney disease through reduction in proteinuria.
Topics: Angiotensin II; Animals; Apoptosis; Biopsy; Blood Pressure; Disease Models, Animal; Endoplasmic Reticulum Stress; Fibrosis; Gene Expression Profiling; Humans; Hypertension; Inflammation; Male; Mice; Mice, Knockout; Nephrosclerosis; Phenylbutyrates; Proteinuria; Renal Insufficiency, Chronic; Transcription Factor CHOP; Transcriptome; Urinalysis | 2017 |
Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model.
Topics: Angiotensin II; Biomechanical Phenomena; Blood Vessels; Cytoskeleton; Disease Progression; Humans; Induced Pluripotent Stem Cells; Inflammation; Lab-On-A-Chip Devices; Lovastatin; Microfluidics; Myocytes, Smooth Muscle; Phenotype; Progeria | 2017 |
The correlation between inflammatory injury induced by LPS and RAS in EpH4-Ev cells.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Line; Epithelial Cells; Female; Humans; Inflammation; Interleukin-6; Interleukin-8; Lipopolysaccharides; Mammary Glands, Human; Mice; NF-kappa B; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Renin-Angiotensin System; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
The flame that lights the fire: oxidative stress, inflammation, and renal damage in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypertension; Inflammation; Inflammation Mediators; Kidney Diseases; Mice; Mice, Knockout; Oxidative Stress | 2008 |
Role of inflammation in the development of renal damage and dysfunction in angiotensin II-induced hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Blotting, Western; Cell Movement; Cell Proliferation; Disease Models, Animal; Glomerular Filtration Rate; Hypertension; Immunohistochemistry; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrosclerosis; Probability; Random Allocation; Reactive Oxygen Species; Receptors, Chemokine; Reference Values; Sensitivity and Specificity | 2008 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressure; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Humans; Hydralazine; Hypertension; Inflammation; Male; NADPH Oxidases; Neurons; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Sodium Chloride; Stroke; Tetrazoles; Valine; Valsartan | 2008 |
Estrogen prevents intestinal inflammation after trauma-hemorrhage via downregulation of angiotensin II and angiotensin II subtype I receptor.
Topics: Angiotensin II; Animals; Cytokines; Down-Regulation; Estradiol; Fulvestrant; Hemorrhage; Inflammation; Male; Peroxidase; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2008 |
Inflammation, angiotensin II, and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Immunosuppressive Agents; Inflammation; Mice; Mice, Knockout; Oxidative Stress; Rats; Rats, Inbred Dahl; Receptors, CCR2 | 2008 |
Actions of aldosterone in the cardiovascular system: the good, the bad, and the ugly?
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiovascular System; ErbB Receptors; Homeostasis; Hypertension; Inflammation; Receptors, Mineralocorticoid; Signal Transduction | 2009 |
Downregulating osteopontin reduces angiotensin II-induced inflammatory activation in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Atherosclerosis; Down-Regulation; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Osteopontin; RNA, Small Interfering; Transcription Factor AP-1 | 2009 |
Angiotensin II infusion in man is proinflammatory but has no short-term effects on thrombin generation in vivo.
Topics: Adult; Angiotensin II; Antithrombins; Case-Control Studies; Female; Fibrinolysis; Humans; Hyperlipidemia, Familial Combined; Inflammation; Infusions, Intravenous; Interleukin-6; Leukocyte Count; Male; Middle Aged; Peptide Fragments; Plasminogen Activator Inhibitor 1; Prothrombin; Thrombin; Time Factors; Tissue Plasminogen Activator; Tumor Necrosis Factor-alpha | 2009 |
High ambient glucose augments angiotensin II-induced proinflammatory gene mRNA expression in human mesangial cells: effects of valsartan and simvastatin.
Topics: Angiotensin II; Gene Expression Regulation; Glucose; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Inflammation; Kidney; Mesangial Cells; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Tetrazoles; Valine; Valsartan | 2009 |
Rosuvastatin protects against angiotensin II-induced renal injury in a dose-dependent fashion.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Collagen Type IV; Disease Models, Animal; Dose-Response Relationship, Drug; Fibronectins; Fluorescent Antibody Technique, Indirect; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Kidney Cortex; Kidney Medulla; Male; Monocytes; Necrosis; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Rosuvastatin Calcium; Sulfonamides | 2009 |
Regulation of urocortin I and its related peptide urocortin II by inflammatory and oxidative stresses in HL-1 cardiomyocytes.
Topics: Angiotensin II; Animals; Base Sequence; Cell Line; DNA Primers; DNA, Complementary; Inflammation; Lipopolysaccharides; Mice; Myocardium; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Urocortins | 2009 |
Osteopontin modulates angiotensin II-induced inflammation, oxidative stress, and fibrosis of the kidney.
Topics: Angiotensin II; Animals; Fibrosis; Inflammation; Kidney; Mice; Mice, Knockout; Osteopontin; Oxidative Stress | 2009 |
Chymase activity is closely related with plaque vulnerability in a hamster model of atherosclerosis.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Apoptosis; Atherosclerosis; Body Weight; Cell Degranulation; Cholesterol; Chymases; Cricetinae; Disease Models, Animal; Disease Progression; Immunohistochemistry; Inflammation; Inflammation Mediators; Lipids; Male; Mast Cells; Mesocricetus; Microscopy, Electron, Transmission; ortho-Aminobenzoates; Ovalbumin; Peptidyl-Dipeptidase A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rupture; Time Factors; Ultrasonography, Doppler, Duplex | 2009 |
Angiotensin II stimulates MCP-1 production in rat glomerular endothelial cells via NAD(P)H oxidase-dependent nuclear factor-kappa B signaling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Chemokine CCL2; Endothelial Cells; Enzyme Inhibitors; Inflammation; Kidney Glomerulus; NADPH Oxidases; NF-kappa B; Onium Compounds; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Telmisartan | 2009 |
Liver X receptors are negative regulators of cardiac hypertrophy via suppressing NF-kappaB signalling.
Topics: Adenoviridae; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; DNA-Binding Proteins; Hydrocarbons, Fluorinated; Inflammation; Lipopolysaccharides; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Sulfonamides; Toll-Like Receptor 4 | 2009 |
PPARalpha activator fenofibrate modulates angiotensin II-induced inflammatory responses in vascular smooth muscle cells via the TLR4-dependent signaling pathway.
Topics: Angiotensin II; Animals; Base Sequence; Blotting, Western; Cells, Cultured; DNA Primers; Enzyme-Linked Immunosorbent Assay; Fenofibrate; Fluorescent Antibody Technique; Inflammation; Male; Muscle, Smooth, Vascular; Polymerase Chain Reaction; PPAR alpha; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4 | 2009 |
Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation.
Topics: Adipose Tissue; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Cell Movement; Cytokines; Dietary Fats; Inflammation; Insulin Resistance; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; Systole | 2009 |
Assessment of macrophage infiltration in a murine model of abdominal aortic aneurysm.
Topics: Analysis of Variance; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Contrast Media; Dextrans; Disease Models, Animal; Ferrosoferric Oxide; Image Processing, Computer-Assisted; Inflammation; Infusion Pumps, Implantable; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice | 2009 |
Identification of splenic reservoir monocytes and their deployment to inflammatory sites.
Topics: Angiotensin II; Animals; Antigens, Ly; Bone Marrow Cells; Cell Differentiation; Cell Movement; Cell Size; Female; Inflammation; Mice; Mice, Inbred C57BL; Monocytes; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Receptors, Angiotensin; Spleen; Splenectomy | 2009 |
Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Heart Diseases; Heart Ventricles; Hypertension; Hypertrophy; Inflammation; Macrophages; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta; Ventricular Remodeling | 2009 |
Negative action of hepatocyte growth factor/c-Met system on angiotensin II signaling via ligand-dependent epithelial growth factor receptor degradation mechanism in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Cell Proliferation; Cells, Cultured; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Hepatocyte Growth Factor; Humans; Hyperplasia; Inflammation; Intercellular Signaling Peptides and Proteins; Ligands; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Reactive Oxygen Species; Receptors, Growth Factor; RNA Interference; Signal Transduction; Superoxide Dismutase; Time Factors; Transfection; Ubiquitination | 2009 |
Understanding abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cyclophilin A; Humans; Hyperlipidemias; Inflammation; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species | 2009 |
Shear stress regulates angiotensin type 1 receptor expression in endothelial cells.
Topics: Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Down-Regulation; Endothelial Cells; Humans; Inflammation; Injections, Intravenous; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Protein Kinase Inhibitors; Pulsatile Flow; Receptor, Angiotensin, Type 1; Regional Blood Flow; RNA, Messenger; Signal Transduction; Stress, Mechanical; Time Factors; Vascular Cell Adhesion Molecule-1 | 2009 |
Biomarkers of inflammation and endothelial dysfunction and risk of hypertension among Inner Mongolians in China.
Topics: Adult; Angiotensin II; Asian People; Biomarkers; Blood Pressure; Blood Proteins; C-Reactive Protein; China; Cross-Sectional Studies; E-Selectin; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Male; Middle Aged; Renin; Risk Factors | 2010 |
Angiotensin II regulates the expression of monocyte chemoattractant protein-1 in pancreatic cancer cells.
Topics: Adenocarcinoma; Angiotensin II; Blotting, Western; Cell Line, Tumor; Chemokine CCL2; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Immunohistochemistry; Inflammation; Losartan; NF-kappa B; Pancreatic Neoplasms; Promoter Regions, Genetic; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured | 2009 |
Matrix metalloproteinase-8 and the regulation of blood pressure, vascular inflammation, and atherosclerotic lesion growth.
Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Disease Progression; Humans; Inflammation; Matrix Metalloproteinase 8; Mice; Mice, Knockout; Vascular Cell Adhesion Molecule-1 | 2009 |
Angiotensin II up-regulates CX3CR1 expression in THP-1 monocytes: impact on vascular inflammation and atherogenesis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Cell Adhesion; Cell Movement; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Endothelial Cells; Gene Expression Regulation; Humans; Inflammation; Jurkat Cells; Losartan; Monocytes; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Vasculitis; Vasoconstrictor Agents | 2010 |
An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Base Sequence; Chemokine CCL2; Coculture Techniques; Connective Tissue; Disease Models, Animal; DNA Primers; Humans; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, CCR2; Signal Transduction | 2009 |
Induction of hypertension and peripheral inflammation by reduction of extracellular superoxide dismutase in the central nervous system.
Topics: Adenoviridae; Angiotensin II; Animals; Blood Pressure Determination; Central Nervous System; Disease Models, Animal; Heart Rate; Hypertension; Inflammation; Inflammation Mediators; Integrases; Mice; Mice, Inbred C57BL; Oxidative Stress; Random Allocation; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase | 2010 |
Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis Regulatory Proteins; Cells, Cultured; Cytokine TWEAK; Gene Expression; Inflammation; Losartan; Male; Membrane Proteins; Myocardial Infarction; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; RNA, Messenger; Signal Transduction; Stress, Mechanical; Tumor Necrosis Factors; TWEAK Receptor; Ventricular Remodeling | 2010 |
TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm, Abdominal; Disease Progression; Inflammation; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Transforming Growth Factor beta; Ultrasonography | 2010 |
C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; C-Reactive Protein; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart; Heart Rate; Humans; Hypertension; Immunohistochemistry; Inflammation; Interleukin-1beta; Mice; Myocardium; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Tumor Necrosis Factor-alpha; Up-Regulation; Ventricular Remodeling | 2010 |
Prenatal exposure to inflammation induced by zymosan results in activation of intrarenal renin-angiotensin system in adult offspring rats.
Topics: Angiotensin II; Animals; Blood Pressure; Creatinine; Female; Gene Expression; Hypertension; Inflammation; Kidney Function Tests; Kidney Glomerulus; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; RNA, Messenger; Zymosan | 2010 |
Smad3 mediates cardiac inflammation and fibrosis in angiotensin II-induced hypertensive cardiac remodeling.
Topics: Angiotensin II; Animals; Chemokine CCL2; Echocardiography; Gene Deletion; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Smad3 Protein; Stroke Volume; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2010 |
Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells.
Topics: Angiotensin II; Calcium; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Diltiazem; Endothelial Cells; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Inflammation; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidase 5; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proliferating Cell Nuclear Antigen; Pyrones; Quinolines; rac1 GTP-Binding Protein; RNA Interference; RNA, Messenger; Signal Transduction; Superoxides; Time Factors; Vascular Cell Adhesion Molecule-1 | 2010 |
Hypertension, obesity, and inflammation: the complex designs of a deadly trio.
Topics: Adaptive Immunity; Angiotensin II; Atherosclerosis; Genes, ras; Humans; Hypertension; Inflammation; Insulin Resistance; Metabolic Syndrome; Obesity; Oxidative Stress | 2010 |
Plasma concentration of visfatin is a new surrogate marker of systemic inflammation in type 2 diabetic patients.
Topics: 3T3-L1 Cells; Adult; Aged; Angiotensin II; Animals; Biomarkers; Blotting, Western; Diabetes Mellitus, Type 2; Female; Gene Expression; Glucose; Humans; Inflammation; Male; Mice; Middle Aged; NF-kappa B; Nicotinamide Phosphoribosyltransferase; Polymerase Chain Reaction | 2010 |
Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cell Adhesion Molecules; Cell Proliferation; Cystatin C; Humans; Inflammation; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle | 2010 |
Losartan inhibits LPS-induced inflammatory signaling through a PPARgamma-dependent mechanism in human THP-1 macrophages.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Atherosclerosis; Cell Line; Gene Expression; Humans; Hypertension; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Losartan; Macrophages; Monocytes; Phosphorylation; PPAR gamma; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Signal Transduction | 2010 |
Angiotensin II induces C-reactive protein expression through ERK1/2 and JNK signaling in human aortic endothelial cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Aorta; Atherosclerosis; Blotting, Western; C-Reactive Protein; Cells, Cultured; Endothelial Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Up-Regulation | 2010 |
Brain microglial cytokines in neurogenic hypertension.
Topics: Angiotensin II; Animals; Anti-Bacterial Agents; Blood Pressure; Brain; Cytokines; Gene Transfer Techniques; Heart Rate; Immunohistochemistry; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Microglia; Minocycline; Prosencephalon; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 2010 |
The CARMA3-Bcl10-MALT1 signalosome promotes angiotensin II-dependent vascular inflammation and atherogenesis.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Atherosclerosis; B-Cell CLL-Lymphoma 10 Protein; Blood Vessels; CARD Signaling Adaptor Proteins; Caspases; Endothelium, Vascular; Inflammation; Mice; Mice, Knockout; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Muscle, Smooth, Vascular; Neoplasm Proteins; NF-kappa B; Receptor, Angiotensin, Type 1; Signal Transduction | 2010 |
HO-1 attenuates hypertension-induced inflammation/oxidative stress: support from Bartter's/Gitelman's patients.
Topics: Aldosterone; Angiotensin II; Bartter Syndrome; Blood Pressure; Heme Oxygenase-1; Humans; Hypertension; Inflammation; Oxidative Stress; Renin-Angiotensin System; Vascular Resistance | 2010 |
Group X secretory phospholipase A(2) augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Group X Phospholipases A2; Humans; Inflammation; Interleukins; Metalloproteases; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2011 |
Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension.
Topics: Adiponectin; Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Genetic Therapy; Genetic Vectors; HEK293 Cells; Heme Oxygenase-1; Humans; Hypertension; Inflammation; Kidney; Lentivirus; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Vasodilation | 2011 |
Adrenomedullin attenuates aortic cross-clamping-induced myocardial injury in rats.
Topics: Adrenomedullin; Angiotensin II; Animals; Aorta; Apoptosis; Biomarkers; Caspase 3; Catalase; Constriction; Endothelin-1; Immunohistochemistry; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Troponin I; Tumor Necrosis Factor-alpha | 2011 |
Deletion of EP4 on bone marrow-derived cells enhances inflammation and angiotensin II-induced abdominal aortic aneurysm formation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Bone Marrow Cells; Bone Marrow Transplantation; Chemokine CCL2; Elastin; Female; Gene Deletion; Hyperlipidemias; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Receptors, LDL; Receptors, Prostaglandin E, EP4 Subtype; Risk Factors | 2011 |
The frail renin-angiotensin system.
Topics: Aged; Aging; Angiotensin II; Apoptosis; Disease Progression; Frail Elderly; Humans; Hypertension; Inflammation; Oxidative Stress; Reactive Oxygen Species; Receptors, Angiotensin; Renin-Angiotensin System | 2011 |
Aortic adventitial fibroblasts participate in angiotensin-induced vascular wall inflammation and remodeling.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Coculture Techniques; Connective Tissue; Culture Media, Conditioned; Cytokines; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibrosis; Flow Cytometry; Humans; Immunohistochemistry; Inflammation; Inflammation Mediators; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Paracrine Communication; Polymerase Chain Reaction; Receptors, CCR2; Time Factors | 2011 |
Mitogen-activated protein kinase-activated protein kinase 2 in angiotensin II-induced inflammation and hypertension: regulation of oxidative stress.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blotting, Western; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Hypertension; Inflammation; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NADPH Oxidases; NF-kappa B; Oxidative Stress; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Superoxides; Vascular Cell Adhesion Molecule-1 | 2011 |
Association of elevated inflammatory and endothelial biomarkers with prehypertension among Mongolians in China.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Biomarkers; Blood Pressure; Body Weight; C-Reactive Protein; Cross-Sectional Studies; E-Selectin; Endothelium, Vascular; Female; Humans; Inflammation; Intercellular Adhesion Molecule-1; Life Style; Male; Middle Aged; Mongolia; Prehypertension; Prevalence; Retrospective Studies; Risk Factors | 2011 |
Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Collagen; Cytokines; Female; Fibrosis; Gene Expression; Humans; Immunohistochemistry; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Cyclooxygenase 2; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Inflammation; Inflammation Mediators; Infusions, Parenteral; Male; Membrane Glycoproteins; Mice; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Peroxynitrous Acid; RNA, Messenger; Superoxides; Time Factors; Up-Regulation; Vascular Cell Adhesion Molecule-1; Vasodilation; Vasodilator Agents | 2011 |
Angiotensin II induces NF-κB, JNK and p38 MAPK activation in monocytic cells and increases matrix metalloproteinase-9 expression in a PKC- andRho kinase-dependent manner.
Topics: Angiotensin II; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 9; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction; U937 Cells | 2011 |
Endothelial enriched microRNAs regulate angiotensin II-induced endothelial inflammation and migration.
Topics: Angiotensin II; Atherosclerosis; Cell Adhesion; Cell Movement; Endothelium, Vascular; Humans; Inflammation; Jurkat Cells; MicroRNAs; Proto-Oncogene Protein c-ets-1; Receptor, Angiotensin, Type 1 | 2011 |
Pivotal role of protein kinase Cdelta in angiotensin II-induced endothelial cyclooxygenase-2 expression: a link to vascular inflammation.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Blotting, Western; Cells, Cultured; Chemokine CCL2; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Inflammation; Inflammation Mediators; Male; Mesenteric Arteries; Middle Aged; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; RNA Interference; Signal Transduction; Time Factors; Tissue Culture Techniques; Up-Regulation | 2011 |
Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Animals, Newborn; Apolipoproteins E; Bone Marrow Cells; Bone Marrow Transplantation; Cardiomegaly; Cell Communication; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclophilin A; Disease Models, Animal; Fibroblasts; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recombinant Proteins; Time Factors | 2011 |
Angiotensin II infusion-induced inflammation, monocytic fibroblast precursor infiltration, and cardiac fibrosis are pressure dependent.
Topics: Angiotensin II; Animals; Blood Pressure; Fibrosis; Hydralazine; Hypertrophy, Left Ventricular; Inflammation; Inflammation Mediators; Infusion Pumps; Leukocyte Common Antigens; Male; Mice; Mice, Inbred C57BL; Monocytes; Myofibroblasts; Random Allocation | 2011 |
Ang II Upregulation of the T-lymphocyte renin-angiotensin system is amplified by low-grade inflammation in human hypertension.
Topics: Aged; Angiotensin II; C-Reactive Protein; Female; Humans; Hypertension; Inflammation; Male; Middle Aged; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; T-Lymphocytes; Up-Regulation | 2011 |
Proinflammatory protein CARD9 is essential for infiltration of monocytic fibroblast precursors and cardiac fibrosis caused by Angiotensin II infusion.
Topics: Angiotensin II; Animals; CARD Signaling Adaptor Proteins; Fibrosis; Inflammation; Interleukin-1beta; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Knockout; Myocardium; Myofibroblasts; NF-kappa B; Transforming Growth Factor beta | 2011 |
Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice.
Topics: Aged; Angiotensin II; Animals; Antibodies, Neutralizing; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Cells, Cultured; Dendritic Cells; Dietary Fats; Disease Models, Animal; Female; Humans; Inflammation; Interferon-gamma; Interleukin-17; Ligation; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Nitric Oxide; Spleen; Superoxides; Time Factors | 2011 |
Statins exert differential effects on angiotensin II-induced atherosclerosis, but no benefit for abdominal aortic aneurysms.
Topics: Angiotensin II; Animal Feed; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Atorvastatin; Blood Pressure; Fluorobenzenes; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides | 2011 |
New take on the role of angiotensin II in cardiac hypertrophy and fibrosis.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Fibrosis; Humans; Hypertension; Inflammation; Mice; Myocardium; Oxidative Stress; Receptor, Angiotensin, Type 1; Sodium; Ventricular Remodeling | 2011 |
Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation.
Topics: Adipose Tissue; Angiotensin II; Humans; Hyperoxia; Inflammation; Insulin Resistance; Isoproterenol; Male; Microcirculation; Middle Aged; Mitochondria; Obesity; Oxygen; Oxygen Consumption; Regional Blood Flow; Thinness; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Angiotensin II modulates interleukin-1β-induced inflammatory gene expression in vascular smooth muscle cells via interfering with ERK-NF-κB crosstalk.
Topics: Angiotensin II; Animals; Aorta; Apolipoproteins E; Cardiovascular Diseases; Down-Regulation; Dual Specificity Phosphatase 1; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Gene Knockdown Techniques; Inflammation; Interleukin-1beta; Mice; Mice, Mutant Strains; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Ribosomal Protein S6 Kinases, 90-kDa; Vascular Cell Adhesion Molecule-1 | 2011 |
Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin.
Topics: Angiotensin II; Animals; Cholesterol; Disease Models, Animal; Doxorubicin; Endothelin-1; Fluorescent Antibody Technique; Inflammation; Inflammation Mediators; Kidney; Losartan; Male; Nephrosis; Proteinuria; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides; Weight Gain | 2011 |
Inflammation and hypertension: the interplay of interleukin-6, dietary sodium, and the renin-angiotensin system in humans.
Topics: Adult; Angiotensin II; C-Reactive Protein; Diet, Sodium-Restricted; Female; Humans; Hypertension; Inflammation; Interleukin-6; Male; Middle Aged; Multivariate Analysis; Renin; Renin-Angiotensin System | 2011 |
Chinese red yeast rice attenuates the development of angiotensin II-induced abdominal aortic aneurysm and atherosclerosis.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Biological Products; Chemokine CCL2; Cholesterol; Inflammation; Interleukin-1alpha; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Plant Extracts; Tunica Intima | 2012 |
A physiological concentration of glucocorticoid inhibits the pro-inflammatory cytokine-induced proliferation of adult rat cardiac fibroblasts: roles of extracellular signal-regulated kinase 1/2 and nuclear factor-κB.
Topics: Angiotensin II; Animals; Cell Growth Processes; Cells, Cultured; Cyclin D1; Hydrocortisone; Inflammation; Inflammation Mediators; Interleukin-1beta; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Myofibroblasts; NF-kappa B; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Signal Transduction; Tumor Necrosis Factor-alpha; Up-Regulation | 2011 |
Possible role of nitric oxide generated by leukocytes in the pathogenesis of hypertensive cerebral edema in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Brain Edema; Cell Adhesion; Endothelial Cells; Hypertension; Inflammation; Leukocytes; Male; Microscopy, Confocal; NF-kappa B; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2011 |
Renin released from mast cells activated by circulating MCP-1 initiates the microvascular phase of the systemic inflammation of alveolar hypoxia.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Cell Degranulation; Cells, Cultured; Chemokine CCL2; Hypoxia; Immunohistochemistry; Inflammation; Macrophage Activation; Macrophages, Peritoneal; Peptidyl-Dipeptidase A; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, CCR2; Renin; Renin-Angiotensin System | 2011 |
Involvement of cytochrome P-450 1B1 in renal dysfunction, injury, and inflammation associated with angiotensin II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Aryl Hydrocarbon Hydroxylases; Blood Pressure; Cytochrome P-450 CYP1B1; Endothelium, Vascular; Hemodynamics; Hypertension, Renal; Inflammation; Kidney; Male; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Stilbenes | 2012 |
Drugs of the future for Peyronie's disease.
Topics: Adult; Angiotensin II; Animals; Connective Tissue Growth Factor; Disease Models, Animal; Drug Design; Drug Therapy; Endothelin-1; Fibrosis; Humans; Inflammation; Male; Middle Aged; Penile Induration; Platelet-Derived Growth Factor; Transforming Growth Factor beta1; Wound Healing | 2012 |
Angiotensin II signalling and calcineurin in cardiac fibroblasts: differential effects of calcineurin inhibitors FK506 and cyclosporine A.
Topics: Angiotensin II; Animals; Calcineurin; Cell Proliferation; Cyclosporine; Fibroblasts; Immunosuppressive Agents; Inflammation; Mitogen-Activated Protein Kinases; Myocardium; Phosphorylation; Rats; Rats, Inbred WKY; Signal Transduction; Tacrolimus | 2012 |
Co-effect of insulin resistance and biomarkers of inflammation and endothelial dysfunction on hypertension.
Topics: Adult; Angiotensin II; Asian People; Biomarkers; Blood Glucose; C-Reactive Protein; E-Selectin; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation; Insulin; Insulin Resistance; Intercellular Adhesion Molecule-1; Male; Middle Aged; Prevalence; Risk | 2012 |
Effect of angiotensin II on inflammation pathways in human primary bone cell cultures in otosclerosis.
Topics: Adult; Angiotensin II; Cells, Cultured; Chemokine CCL3; Chemokine CXCL10; Female; Humans; Inflammation; Interleukin-1; Male; Middle Aged; Osteocytes; Otosclerosis; Receptors, Tumor Necrosis Factor; Signal Transduction; Stapes; Tissue Inhibitor of Metalloproteinase-2 | 2012 |
Alteration of embryonic AT(2)-R and inflammatory cytokines gene expression induced by prenatal exposure to lipopolysaccharide affects renal development.
Topics: Angiotensin II; Animals; Apoptosis; Cytokines; Embryo, Mammalian; Female; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Kidney; Kidney Function Tests; Lipopolysaccharides; Oligonucleotide Array Sequence Analysis; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction | 2013 |
MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Cell Proliferation; Gene Expression Profiling; Humans; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; MicroRNAs; Nicotine; Pancreatic Elastase; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Sus scrofa; Up-Regulation | 2012 |
T lymphocytes and vascular inflammation contribute to stress-dependent hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Blood Pressure; Corticotropin-Releasing Hormone; Gene Expression Regulation; Genes, RAG-1; Hypertension; Inflammation; Lymphocyte Activation; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Stress, Psychological; T-Lymphocytes; Vascular Diseases | 2012 |
Benzo[a]pyrene potentiates the pathogenesis of abdominal aortic aneurysms in apolipoprotein E knockout mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Benzo(a)pyrene; Cyclophilin A; Inflammation; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Tumor Necrosis Factor-alpha | 2012 |
Role of angiotensin II in the brain inflammatory events during experimental diabetes in rats.
Topics: Angiotensin II; Animals; Blood Glucose; Brain; Catalase; CD8 Antigens; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Inflammation; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Macrophages; Male; Monocytes; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Superoxides | 2012 |
Serum-glucocorticoid regulated kinase 1 regulates alternatively activated macrophage polarization contributing to angiotensin II-induced inflammation and cardiac fibrosis.
Topics: Angiotensin II; Animals; Cell Polarity; Cells, Cultured; Fibrosis; Immediate-Early Proteins; Inflammation; Leukocyte Common Antigens; Macrophage Activation; Macrophages; Male; Mice; Myocardium; Protein Serine-Threonine Kinases; STAT3 Transcription Factor | 2012 |
Reciprocal interaction between macrophages and T cells stimulates IFN-γ and MCP-1 production in Ang II-induced cardiac inflammation and fibrosis.
Topics: Angiotensin II; Animals; Body Weight; Chemokine CCL2; Fibrosis; Inflammation; Interferon-gamma; Mice; Mice, Knockout; Myocardium; T-Lymphocytes | 2012 |
Dexamethasone blocks the systemic inflammation of alveolar hypoxia at several sites in the inflammatory cascade.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Cell Degranulation; Cells, Cultured; Chemokine CCL2; Dexamethasone; Hypoxia; Inflammation; Macrophages, Alveolar; Male; Mast Cells; Mesentery; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley | 2012 |
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Biomarkers; Blood Pressure; Cytochrome P-450 CYP11B2; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Diseases; Inflammation; Kidney Diseases; Kidney Glomerulus; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Myocardium; Receptors, Mineralocorticoid; Renin-Angiotensin System; Sodium Chloride, Dietary; Spironolactone; Time Factors; Vascular Diseases | 2012 |
Smooth muscle-specific expression of calcium-independent phospholipase A2β (iPLA2β) participates in the initiation and early progression of vascular inflammation and neointima formation.
Topics: Angiotensin II; Animals; Blotting, Western; Calcium; Carotid Arteries; Cells, Cultured; Immunohistochemistry; Inflammation; Mice; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; Neointima; Oligonucleotides, Antisense; Phospholipases A2, Calcium-Independent; Polymerase Chain Reaction; Promoter Regions, Genetic; Rabbits; Rats; Rats, Sprague-Dawley | 2012 |
ACE2 deficiency enhances angiotensin II-mediated aortic profilin-1 expression, inflammation and peroxynitrite production.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta; Blotting, Western; Chemokine CCL2; Ethidium; Inflammation; Interleukin-1beta; Interleukin-6; Mice; Mice, Knockout; NADPH Oxidases; Peptidyl-Dipeptidase A; Peroxynitrous Acid; Profilins; Real-Time Polymerase Chain Reaction; Tyrosine | 2012 |
Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model.
Topics: Angiotensin II; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apoptosis; Azo Compounds; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Endothelial Cells; Fenofibrate; Inflammation; Kidney; Lipoproteins, HDL; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; Sphingosine; Treatment Outcome; Up-Regulation | 2012 |
Cardiac kallikrein-kinin system is upregulated in chronic volume overload and mediates an inflammatory induced collagen loss.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aprotinin; Bradykinin; Catecholamines; Cell Count; Cell Degranulation; Chymases; Collagen; Extracellular Fluid; Gelatinases; Heart Ventricles; Hemodynamics; Immunohistochemistry; Inflammation; Kallikrein-Kinin System; Mast Cells; Models, Cardiovascular; Myocardium; Peptidyl-Dipeptidase A; Rats; Receptors, Bradykinin; RNA, Messenger; Ultrasonography; Up-Regulation; Vascular Fistula; Ventricular Remodeling | 2012 |
Suppressing inflammation by inhibiting the NF-κB pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Inflammatory Agents; Behavior, Animal; Cerebrovascular Circulation; Imidazoles; Infarction, Middle Cerebral Artery; Inflammation; Male; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2012 |
Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cathepsin K; Cathepsins; CD3 Complex; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; T-Lymphocytes; Time Factors | 2012 |
Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension.
Topics: Angiotensin II; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Hypertension; Immunity, Innate; Inflammation; Macrophages; Male; Neurotransmitter Agents; Nicotine; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spleen | 2012 |
Role of the transcription factor erythroblastosis virus E26 oncogen homolog-1 (ETS-1) as mediator of the renal proinflammatory and profibrotic effects of angiotensin II.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Fibrosis; Gene Expression; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Inflammation; Ki-67 Antigen; Kidney; Kidney Cortex; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; NADPH Oxidase 4; NADPH Oxidases; Peptides; Proto-Oncogene Protein c-ets-1; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Expression of endothelial lipase correlates with the size of neointima in a murine model of vascular remodeling.
Topics: Angiotensin II; Animals; Carotid Artery, Common; Cell Adhesion; Cell Movement; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Lipase; Lipoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Neointima; Oxidative Stress | 2012 |
Epigallocatechin-3-gallate inhibits angiotensin II and interleukin-6-induced C-reactive protein production in macrophages.
Topics: Angiotensin II; Anti-Inflammatory Agents; C-Reactive Protein; Cardiovascular Diseases; Catechin; Cell Line, Tumor; Humans; Inflammation; Interleukin-6; Macrophages; Reactive Oxygen Species; RNA, Messenger; Tea; U937 Cells | 2012 |
Interferon-γ signaling inhibition ameliorates angiotensin II-induced cardiac damage.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Heart; Inflammation; Interferon-gamma; Interleukin-17; Interleukin-23; Kidney; Membrane Proteins; Mice; Mice, Knockout; Microfilament Proteins; Myocardium; Podocytes; Signal Transduction | 2012 |
Ang II induce kidney damage by recruiting inflammatory cells and up regulates PPAR gamma and Renin 1 gene: effect of β carotene on chronic renal damage.
Topics: Angiotensin II; Animals; Apolipoproteins E; beta Carotene; Cell Movement; Female; Inflammation; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Polycystic Kidney Diseases; PPAR gamma; Renal Insufficiency, Chronic; Renin | 2013 |
Clustering of inflammatory biomarkers and risk of hypertension in a Mongolian population in China.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Asian People; C-Reactive Protein; China; Female; Genetic Markers; Genetic Predisposition to Disease; Humans; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Male; Middle Aged; Young Adult | 2012 |
The influence of sodium- and calcium-regulatory hormone interventions on adipocytokines in obesity and diabetes.
Topics: Adipokines; Adult; Aged; Angiotensin II; Arterial Pressure; Biomarkers; Calcium; Cholecalciferol; Diabetes Mellitus; Female; Glycated Hemoglobin; Hormones; Humans; Inflammation; Infusions, Intravenous; Male; Middle Aged; Obesity; Renin-Angiotensin System; Resistin; Sodium; Young Adult | 2013 |
Angiotensin (1-7) ameliorates angiotensin II-induced inflammation by inhibiting LOX-1 expression.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Adhesion; Chemokine CCL2; DNA; Endothelial Cells; Female; Humans; Inflammation; Male; NF-kappa B; Peptide Fragments; Rabbits; Scavenger Receptors, Class E; Vascular Cell Adhesion Molecule-1 | 2013 |
Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Inflammation; Integrases; Mice; Mice, Transgenic; NADPH Oxidases; Oxidation-Reduction; Protein Subunits; Reactive Oxygen Species; Subfornical Organ | 2013 |
Atrial natriuretic peptide exerts protective action against angiotensin II-induced cardiac remodeling by attenuating inflammation via endothelin-1/endothelin receptor A cascade.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Endothelin-1; Fibrillar Collagens; Fibroblasts; Fibrosis; Heart Diseases; Inflammation; Inflammation Mediators; Infusions, Intravenous; Macrophages; Male; Mitral Valve; Myocardial Contraction; Myocardium; Rats; Rats, Inbred WKY; Receptor, Endothelin A; Signal Transduction; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2013 |
Clopidogrel, a platelet P2Y12 receptor inhibitor, reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Platelets; Blood Pressure Determination; Clopidogrel; Cytokines; Immunoenzyme Techniques; Inflammation; Macrophages, Peritoneal; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Aggregation Inhibitors; Reactive Oxygen Species; Receptors, Purinergic P2Y12; Ticlopidine; Vasculitis; Vasoconstrictor Agents | 2012 |
Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice.
Topics: Angiotensin II; Animals; Fibrosis; Gene Expression Regulation; Hypertension; Inflammation; Kidney; Kidney Diseases; Male; Mice; Mice, Knockout; MicroRNAs; NF-kappa B; Proteinuria; Signal Transduction; Smad3 Protein; Smad7 Protein; Sp1 Transcription Factor; Transforming Growth Factor beta | 2013 |
Cross-talk between inflammation and angiotensin II: studies based on direct transfection of cardiomyocytes with AT1R and AT2R cDNA.
Topics: Angiotensin II; Animals; Apoptosis; Cell Line; Cytokines; DNA, Complementary; Extracellular Signal-Regulated MAP Kinases; Inflammation; Inflammation Mediators; Lipopolysaccharides; Mice; Myocytes, Cardiac; NF-kappa B; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Scavenger Receptors, Class E; Signal Transduction; Up-Regulation | 2012 |
Immunosuppressive treatment protects against angiotensin II-induced renal damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antigens, CD; B7-2 Antigen; Blood Pressure; Dendritic Cells; Dexamethasone; Etanercept; Histocompatibility Antigens Class II; Humans; Immunoglobulin G; Immunosuppressive Agents; Inflammation; Kidney; Kidney Diseases; Kinetics; Macrophage Migration-Inhibitory Factors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mycophenolic Acid; NADPH Dehydrogenase; NADPH Oxidases; NF-kappa B; Phosphoproteins; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Renin; T-Lymphocytes | 2002 |
PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Cell Adhesion Molecules; Cholesterol; Docosahexaenoic Acids; Endothelium, Vascular; Fatty Acids, Nonesterified; Hypertension; In Vitro Techniques; Inflammation; Male; Mesenteric Arteries; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Renin; Transcription Factors; Triglycerides; Vascular Cell Adhesion Molecule-1; Vasodilator Agents | 2002 |
Oxidative stress is a critical mediator of the angiotensin II signal in human neutrophils: involvement of mitogen-activated protein kinase, calcineurin, and the transcription factor NF-kappaB.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Calcineurin; Calcium; Calcium Signaling; Chelating Agents; DNA; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Humans; Inflammation; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; NADPH Oxidases; Neutrophils; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Protein Transport; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Respiratory Burst; Transcription, Genetic | 2003 |
17 Beta-estradiol attenuates development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Estradiol; Female; Inflammation; Male; Mice | 2003 |
Inflammation-induced vasoconstrictor hyporeactivity is caused by oxidative stress.
Topics: Adult; Angiotensin II; Antioxidants; Ascorbic Acid; Endotoxemia; Escherichia coli Infections; Humans; Inflammation; Male; Oxidative Stress; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Vasopressins | 2003 |
Endotoxin attacks the cardiovascular system: black death at the tollgate.
Topics: Angiotensin II; Antioxidants; Endotoxemia; Humans; Inflammation; Oxidative Stress; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Vasopressins | 2003 |
Entacapone protects from angiotensin II-induced inflammation and renal injury.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Blood Pressure; Cardiomegaly; Catechol O-Methyltransferase; Catechols; Creatinine; Dinoprost; Disease Models, Animal; Dopamine; Enzyme Inhibitors; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; Leukocytes; Male; Models, Cardiovascular; Nitriles; Norepinephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2003 |
Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Movement; Constriction; Coronary Vessels; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Inflammation; Macrophages; Male; Myocardium; Peptidyl-Dipeptidase A; Pressure; Rats; Rats, Wistar; Tetrazoles | 2004 |
Monocyte chemoattractant protein-1 is an essential inflammatory mediator in angiotensin II-induced progression of established atherosclerosis in hypercholesterolemic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Chemokine CCL2; Chemokines; Cytokines; Disease Progression; Gene Expression Regulation; Gene Targeting; Humans; Hyperlipoproteinemia Type II; Imidazoles; Inflammation; Inflammation Mediators; Injections, Intramuscular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Olmesartan Medoxomil; Random Allocation; Recombinant Fusion Proteins; Sequence Deletion; Single-Blind Method; Tetrazoles | 2004 |
PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats.
Topics: Angiotensin II; Animals; Blood Pressure; Collagen; Electrocardiography; Fenofibrate; Fibrosis; Heart; Hypertension; Inflammation; Infusions, Intravenous; Intercellular Adhesion Molecule-1; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
From inflammation to fibrosis: a stiff stretch of highway.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Apoptosis; Cell Adhesion Molecules; Collagen; Coronary Vessels; Cytokines; Fibroblasts; Fibrosis; Humans; Hypertension; Inflammation; Ligation; Macrophages; Myocardium; Myocytes, Cardiac; Necrosis; Oxidative Stress; Rats | 2004 |
Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon.
Topics: Allopurinol; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Capillaries; Captopril; Cell Adhesion; Chemokines; Chemotaxis, Leukocyte; Colon; Constriction; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Gene Expression Regulation; Inflammation; Ischemia; Leukocyte Count; Leukocytes; Losartan; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2004 |
Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPK.
Topics: Adenoviridae; Androstadienes; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Inflammation; Interleukin-1; Isoenzymes; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Vascular Cell Adhesion Molecule-1; Wortmannin | 2004 |
Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Bone Marrow Transplantation; Chemokine CCL2; Chemotaxis, Leukocyte; Enzyme Inhibitors; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Inflammation; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Monocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Olmesartan Medoxomil; Pilot Projects; Radiation Chimera; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, CCR2; Receptors, Chemokine; Recombinant Fusion Proteins; Superoxide Dismutase; Tetrazoles; Up-Regulation | 2004 |
Angiotensin II stimulates the release of interleukin-6 and interleukin-8 from cultured human adipocytes by activation of NF-kappaB.
Topics: Adipocytes; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Electrophoretic Mobility Shift Assay; Female; Humans; Imidazoles; Inflammation; Interleukin-6; Interleukin-8; NF-kappa B; Nitriles; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Pyridines; Receptor, Angiotensin, Type 1; RNA, Messenger; Sulfones; Tetrazoles; Transcription Factor RelA; Transcriptional Activation | 2004 |
Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction.
Topics: Angiotensin II; Animals; Disease Progression; Gene Expression Regulation; Genotype; Immunohistochemistry; Inflammation; Kidney; Kidney Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA; Time Factors; Up-Regulation; Ureteral Obstruction | 2004 |
The answer: angiotensin II. The question: what do inflammation, oxidant stress and fibrogenesis have in common?
Topics: Angiotensin II; Fibrinogen; Humans; Inflammation; Liver Cirrhosis; Oxidative Stress; Vasoconstriction | 2004 |
Cholesterol-lowering independent regression and stabilization of atherosclerotic lesions by pravastatin and by antimonocyte chemoattractant protein-1 therapy in nonhuman primates.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Catheterization; Chemokine CCL2; Chemotaxis; Cholesterol; Cytokines; Diet, Atherogenic; DNA, Complementary; Drug Evaluation, Preclinical; Genetic Therapy; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Iliac Artery; Immunoglobulin G; Immunoglobulin M; Inflammation; Macaca fascicularis; Male; Peptidyl-Dipeptidase A; Phenotype; Pravastatin; Random Allocation; Renin; Transfection | 2004 |
Myocyte enhancer factor 2 mediates vascular inflammation via the p38-dependent pathway.
Topics: Angiotensin II; Animals; Arterial Occlusive Diseases; Chemokine CCL2; DNA-Binding Proteins; Inflammation; Macrophages; MAP Kinase Signaling System; MEF2 Transcription Factors; Muscle, Smooth, Vascular; Myogenic Regulatory Factors; p38 Mitogen-Activated Protein Kinases; Rats; Transcription Factors; Transcriptional Activation | 2004 |
Is vascular endothelial growth factor a missing link between hypertension and inflammation?
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Extracellular Matrix Proteins; Genes, Lethal; Humans; Hypertension; Inflammation; Metabolic Syndrome; Mice; Mice, Knockout; Mice, Transgenic; Muscle, Skeletal; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Rats; Transfection; Transgenes; Vascular Endothelial Growth Factor A | 2004 |
Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Electrophoretic Mobility Shift Assay; Heat-Shock Response; Hot Temperature; HSP70 Heat-Shock Proteins; Hydralazine; Hypertension; Imidazoles; Inflammation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; NF-kappa B; NF-kappa B p50 Subunit; Norepinephrine; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Thiophenes; Transcription Factor RelA | 2004 |
Hypertensive response to acute stress is attenuated in interleukin-6 knockout mice.
Topics: Acute Disease; Adrenergic alpha-Agonists; Angiotensin II; Animals; Blood Pressure; Heart Rate; Housing, Animal; Hypertension; Inflammation; Interleukin-6; Male; Mesenteric Arteries; Mice; Mice, Knockout; Motor Activity; Norepinephrine; Phenylephrine; Renin; Renin-Angiotensin System; Stress, Psychological; Sympathetic Nervous System; Telemetry; Territoriality | 2004 |
Hypertension: a novel regulator of adaptive immunity in atherosclerosis?
Topics: Adaptation, Physiological; Angiotensin II; Animals; Apolipoproteins E; Arteriosclerosis; Collagen; Disease Models, Animal; Fibrosis; Humans; Hypertension; Hypertension, Renovascular; Inflammation; Ligation; Lipids; Macrophages; Mice; Nephrectomy; Phenotype; Rabbits; Renal Artery; Renin-Angiotensin System; Th1 Cells; Th2 Cells | 2004 |
[The renin-angiotensin system and post-ischemic angiogenesis].
Topics: Angiotensin II; Apoptosis; Humans; Inflammation; Ischemia; Neovascularization, Physiologic; Receptor, Angiotensin, Type 2; Regional Blood Flow; Renin-Angiotensin System; Vasoconstrictor Agents | 2004 |
Angiotensin II enhances interleukin-18 mediated inflammatory gene expression in vascular smooth muscle cells: a novel cross-talk in the pathogenesis of atherosclerosis.
Topics: Angiotensin II; Animals; Arteriosclerosis; DNA-Binding Proteins; Gene Expression Regulation; Humans; Inflammation; Interleukin-18; Interleukin-18 Receptor alpha Subunit; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Receptors, Interleukin; Receptors, Interleukin-18; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation | 2005 |
Tubular expression of angiotensin II receptors and their regulation in IgA nephropathy.
Topics: Angiotensin II; Apoptosis; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Epithelial Cells; Gene Expression Regulation; Glomerulonephritis, IGA; Humans; Imidazoles; Immunoblotting; Immunoglobulin A; Immunohistochemistry; Inflammation; Interleukin-6; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Kinetics; Losartan; MAP Kinase Signaling System; Mesangial Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Poly(ADP-ribose) Polymerases; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Recombinant Proteins; Renin-Angiotensin System; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Fibrosis; Heart Diseases; Humans; Inflammation; Kidney Diseases; Losartan; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Renin | 2005 |
Are transcription factors NF-kappaB and AP-1 involved in the ANG II-stimulated production of proinflammatory cytokines induced by LPS in dehydrated rats?
Topics: Angiotensin II; Animals; Cytokines; Dehydration; Inflammation; Interleukin-1; Lipopolysaccharides; Liver; Male; NF-kappa B; Rats; Rats, Wistar; Spleen; Transcription Factor AP-1; Transcription Factors | 2005 |
Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.
Topics: Angiotensin II; Animals; Blood Vessels; Cell Line; Electrophoretic Mobility Shift Assay; Endotoxins; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Female; Flow Cytometry; Glucose; Inflammation; Macrophages; Male; Mice; Ovariectomy; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Sex Characteristics; Tumor Necrosis Factor-alpha | 2005 |
Angiotensin receptors and actions in guinea pig enteric nervous system.
Topics: Angiotensin II; Animals; Blotting, Western; Electrophysiology; Female; Guinea Pigs; Humans; Inflammation; Intestine, Small; Irritable Bowel Syndrome; Male; Membrane Potentials; Myenteric Plexus; Norepinephrine; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synaptic Transmission | 2005 |
Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cells, Cultured; Chemokine CCL2; Cyclin-Dependent Kinase Inhibitor p21; Female; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plasminogen Activator Inhibitor 1; Proto-Oncogene Protein c-ets-1; Tissue Plasminogen Activator; Vascular Cell Adhesion Molecule-1 | 2005 |
Heat shock treatment suppresses angiotensin II-induced SP-1 and AP-1 and stimulates Oct-1 DNA-binding activity in heart.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Blood Pressure; Blotting, Western; Cell Nucleus; DNA; DNA-Binding Proteins; Heat-Shock Proteins; Hot Temperature; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hypertension; Inflammation; Male; Myocardium; Neoplasm Proteins; Octamer Transcription Factor-1; Oligonucleotides; Protein Binding; Rats; Rats, Sprague-Dawley; Signal Transduction; Sp1 Transcription Factor; Time Factors; Transcription Factor AP-1; Transcription Factors | 2005 |
The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IkappaB kinase complex.
Topics: Angiotensin II; Animals; Cell Line; Gene Expression Regulation; Humans; I-kappa B Kinase; Inflammation; Muscle, Smooth, Vascular; Phosphorylation; Rats; Transcription Factor RelA | 2006 |
Early markers of inflammation in a high angiotensin II state--results of studies in Bartter's/Gitelman's syndromes.
Topics: Acute-Phase Proteins; Adolescent; Adult; Angiotensin II; Bartter Syndrome; Biomarkers; Case-Control Studies; Female; Humans; Inflammation; Male; Middle Aged; Tumor Necrosis Factor-alpha | 2006 |
Smad3 mediates angiotensin II- and TGF-beta1-induced vascular fibrosis: Smad3 thickens the plot.
Topics: Angiotensin II; Animals; Fibrosis; Inflammation; Mice; Muscle, Smooth, Vascular; Smad3 Protein; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Angiotensin II upregulates toll-like receptor 4 on mesangial cells.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Cell Line; Inflammation; Kidney Glomerulus; Ligands; Lipopolysaccharides; Mesangial Cells; Mice; NF-kappa B; Rats; Rats, Wistar; Toll-Like Receptor 4; Up-Regulation | 2006 |
Essential role of PKC-zeta in normal and angiotensin II-accelerated neointimal growth after vascular injury.
Topics: Angiotensin II; Animals; Carotid Arteries; Catheterization; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coronary Restenosis; Fibrosis; Gene Expression Regulation, Enzymologic; Inflammation; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tunica Intima | 2006 |
Angiotensin II potentiates inflammatory edema in rats: Role of mast cell degranulation.
Topics: Acute Disease; Angiotensin II; Animals; Anti-Allergic Agents; Carrageenan; Cell Degranulation; Cell Movement; Dextrans; Drug Synergism; Edema; Hindlimb; Inflammation; Interleukin-1beta; Mast Cells; Neutrophils; Peritoneal Cavity; Peroxidase; Pyrilamine; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2006 |
Selective inhibition of p38alpha MAPK improves cardiac function and reduces myocardial apoptosis in rat model of myocardial injury.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Body Weight; Cardiac Output; Caspase 3; Caspases; Enzyme Inhibitors; Heart; Indoles; Inflammation; Male; Mitogen-Activated Protein Kinase 14; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Wistar; Reperfusion Injury; Stroke Volume; Vasoconstrictor Agents | 2006 |
Calcium [corrected] channel blockers reduce angiotensin II-induced superoxide generation and inhibit lectin-like oxidized low-density lipoprotein receptor-1 expression in endothelial cells.
Topics: Angiotensin II; Animals; Aorta; Calcium Channel Blockers; Cell Adhesion Molecules; Cells, Cultured; Chemokine CCL2; Endothelial Cells; Heme Oxygenase-1; Inflammation; Male; NADPH Oxidases; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Scavenger Receptors, Class E; Superoxides | 2006 |
Angiotensin II type 1 receptor-mediated inflammation is required for choroidal neovascularization.
Topics: Angiogenesis Inducing Agents; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cell Line; Cell Movement; Choroidal Neovascularization; Endothelial Cells; Humans; Inflammation; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; PPAR gamma; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Telmisartan; Tissue Distribution | 2006 |
Acute sodium overload produces renal tubulointerstitial inflammation in normal rats.
Topics: Actins; Angiotensin II; Animals; Biological Transport; Blood Pressure; Cell Respiration; Chemokine CCL5; Dose-Response Relationship, Drug; Immunohistochemistry; Inflammation; Kidney Tubules; Male; Nephritis, Interstitial; NF-kappa B; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sodium; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Discoidin domain receptor 1 null mice are protected against hypertension-induced renal disease.
Topics: Angiotensin II; Animals; Chemokine CCL2; Collagen Type I; Collagen Type IV; Cytokines; Discoidin Domain Receptors; Disease Models, Animal; Fibrosis; Hypertension; Inflammation; Kidney Failure, Chronic; Kidney Glomerulus; Lipopolysaccharides; Male; Mice; Mice, Transgenic; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; Shock, Septic; Vasoconstrictor Agents | 2006 |
CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Apoptosis Regulatory Proteins; B-Cell CLL-Lymphoma 10 Protein; CARD Signaling Adaptor Proteins; Caspases; Hepatocytes; Humans; I-kappa B Kinase; Inflammation; Mice; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Receptor, Angiotensin, Type 1; Signal Transduction; Ubiquitin | 2007 |
Regulation of angiotensin II receptors levels during rat induced pulpitis.
Topics: Angiotensin I; Angiotensin II; Animals; Dental Pulp; Inflammation; Male; Pulpitis; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2007 |
Pressure overload-induced transient oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Fibrosis; Heart Ventricles; Hypertension; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazoles; Time Factors; Ventricular Remodeling | 2006 |
PTEN reduces cuff-induced neointima formation and proinflammatory cytokines.
Topics: Adenoviridae; Angiotensin II; Animals; Apoptosis; Atherosclerosis; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Cytokines; Disease Models, Animal; Femoral Artery; Genetic Therapy; Genetic Vectors; I-kappa B Proteins; Inflammation; Interleukin-1beta; Macrophages; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-KappaB Inhibitor alpha; Phosphorylation; PTEN Phosphohydrolase; Rats; Rats, Wistar; RNA, Messenger; Transfection; Tumor Necrosis Factor-alpha; Tunica Intima | 2007 |
Long-term, high-dosage candesartan suppresses inflammation and injury in chronic kidney disease: nonhemodynamic renal protection.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chemokine CCL5; Dose-Response Relationship, Drug; Inflammation; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Male; NF-kappa B; Proteinuria; Rats; Rats, Inbred SHR; Tetrazoles; Vasoconstrictor Agents | 2007 |
Human T and natural killer cells possess a functional renin-angiotensin system: further mechanisms of angiotensin II-induced inflammation.
Topics: Angiotensin II; Cell Movement; Dendritic Cells; Humans; Inflammation; Interferon-gamma; Interleukin-4; Killer Cells, Natural; Lymphocyte Activation; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; T-Lymphocytes | 2007 |
Renal vascular and tubulointerstitial inflammation and proliferation in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Arterioles; Blood Pressure; Blood Vessels; Body Weight; Cell Proliferation; Cytochrome P-450 CYP1A1; Diet; Hypertension, Malignant; Immunohistochemistry; Inflammation; Kidney Cortex; Kidney Glomerulus; Male; Mice; Nephritis, Interstitial; Proliferating Cell Nuclear Antigen; Rats; Renal Circulation; Renin | 2007 |
Anti-inflammatory actions of quinapril.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Humans; Inflammation; Models, Biological; Quinapril; Tetrahydroisoquinolines | 2007 |
Angiotensin II promotes the inflammatory response to CD40 ligation via TRAF-2.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; CD40 Antigens; CD40 Ligand; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Inflammation; Interleukin-6; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Saphenous Vein; TNF Receptor-Associated Factor 2; Up-Regulation | 2007 |
Mycophenolate mofetil administration reduces renal inflammation, oxidative stress, and arterial pressure in rats with lead-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Creatinine; Hypertension; Immunosuppressive Agents; Inflammation; Kidney Diseases; Lead; Lymphocytes; Macrophages; Male; Malondialdehyde; Mycophenolic Acid; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Superoxides; Transcription Factor RelA | 2007 |
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Topics: Albuminuria; Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Humans; Hypertension; I-kappa B Proteins; Inflammation; Intercellular Adhesion Molecule-1; Kidney Diseases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Cardiovascular; Nephritis; NF-kappa B; NF-KappaB Inhibitor alpha; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Specificity; Receptor, TIE-1; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2007 |
Angiotensin II-induced abdominal aortic aneurysm occurs independently of the 5-lipoxygenase pathway in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arachidonate 5-Lipoxygenase; Blood Pressure; Chemokine CCL4; Indoles; Inflammation; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Genetic; Quinolines; Time Factors | 2007 |
Endothelial NF-kappaB as a mediator of kidney damage: the missing link between systemic vascular and renal disease?
Topics: Albuminuria; Angiotensin II; Animals; Atherosclerosis; Endothelium, Vascular; Fibrosis; Gemfibrozil; Humans; Hypertension; I-kappa B Proteins; Inflammation; Kidney Diseases; Mice; Models, Cardiovascular; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Specificity; Sodium Chloride, Dietary | 2007 |
Inflammation in the genesis of hypertension and its complications--the role of angiotensin II.
Topics: Angiotensin II; Anti-Inflammatory Agents; C-Reactive Protein; Cytokines; Humans; Hypertension; Inflammation | 2007 |
CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Cell Adhesion; Cells, Cultured; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Chemokine CCL7; Chemotaxis, Leukocyte; Endothelial Cells; Humans; Inflammation; Leukocytes, Mononuclear; Losartan; Macrophage Inflammatory Proteins; Male; Microcirculation; Monocyte Chemoattractant Proteins; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-8B; Splanchnic Circulation | 2007 |
Angiotensin II type 2 receptor provides an endogenous brake during inflammation-induced microvascular fluid leak.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Capillary Permeability; Endothelium, Vascular; Female; Inflammation; Mesenteric Veins; Microcirculation; Models, Animal; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Vascular Diseases | 2007 |
Linking inflammation and hypertension in humans: studies in Bartter's/Gitelman's syndrome patients.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Bartter Syndrome; Blotting, Western; Case-Control Studies; eIF-2 Kinase; Female; Gitelman Syndrome; Humans; Hypertension; Inflammation; Male; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1 | 2008 |
p38 MAPK inhibition reduces aortic ultrasmall superparamagnetic iron oxide uptake in a mouse model of atherosclerosis: MRI assessment.
Topics: Angiotensin II; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Contrast Media; Enzyme Inhibitors; Feasibility Studies; Ferrosoferric Oxide; Imidazoles; Inflammation; Magnetic Resonance Angiography; Male; Metal Nanoparticles; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Pyrimidines; Vasoconstrictor Agents | 2008 |
Novel anti-inflammatory mechanisms of N-Acetyl-Ser-Asp-Lys-Pro in hypertension-induced target organ damage.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Azo Compounds; Blotting, Western; Cardiomegaly; Cell Separation; Collagen; Fibrosis; Galectin 3; Heart Rate; Hypertension; In Vitro Techniques; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Myocardium; Neutrophil Infiltration; Oligopeptides; Stem Cells; Tumor Necrosis Factor-alpha | 2008 |
Knockout of beta(1)- and beta(2)-adrenoceptors attenuates pressure overload-induced cardiac hypertrophy and fibrosis.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Aorta; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Genotype; Hypertrophy, Left Ventricular; Inflammation; Intercellular Signaling Peptides and Proteins; Ligation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Phenotype; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Signal Transduction; Time Factors; Ventricular Function, Left | 2008 |
Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcium-Binding Proteins; Calpain; Cysteine Proteinase Inhibitors; Disease Models, Animal; Fibrosis; Genetic Therapy; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Inflammation; Infusion Pumps, Implantable; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocardium; NF-kappa B; NFATC Transcription Factors; Renal Artery; Time Factors; Ventricular Remodeling | 2008 |
Dextran sulfate sodium-induced acute colonic inflammation in angiotensin II type 1a receptor deficient mice.
Topics: Angiotensin II; Animals; Body Weight; Colitis; Colon; Dextran Sulfate; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peroxidase; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tumor Necrosis Factor-alpha | 2008 |
PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis.
Topics: Adipokines; Angiotensin II; Animals; Atherosclerosis; Cell Movement; Enzyme Activation; Gene Expression Regulation; Hypercholesterolemia; Hypertriglyceridemia; Inflammation; Ligands; Macrophages; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; PPAR delta; Proto-Oncogene Proteins c-bcl-6; Receptors, LDL; Signal Transduction; Thiazoles; Transcription, Genetic | 2008 |
Osteopontin expression in cardiovascular diseases.
Topics: Angiotensin II; Animals; Arteries; Cardiovascular Diseases; Cell Adhesion; Fibrosis; Gene Expression; Inflammation; Integrins; Kidney; Macrophages; Muscle, Smooth, Vascular; Osteopontin; Rats; Receptors, Cytoadhesin; RNA, Messenger; Sialoglycoproteins; Time Factors; Wound Healing | 1995 |
Vasoactive hormones and autocrine activation of capillary exchange barrier function.
Topics: Acetylcholine; Angiotensin II; Animals; Atrial Natriuretic Factor; Bradykinin; Capillaries; Humans; Hydrostatic Pressure; In Vitro Techniques; Inflammation; Models, Cardiovascular; Muscle, Smooth, Vascular; Norepinephrine; Pressure; Rana pipiens; Recombinant Proteins; Splanchnic Circulation; Vasoconstriction; Vasodilator Agents; Venules | 1993 |
Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats.
Topics: 5-Lipoxygenase-Activating Proteins; Altitude; Angiotensin II; Animals; Arachidonate 5-Lipoxygenase; Cardiomegaly; Carrier Proteins; Endothelium, Vascular; Gene Expression; Hypertension, Pulmonary; Hypoxia; Immunohistochemistry; In Situ Hybridization; Indoles; Inflammation; Lipoxygenase Inhibitors; Male; Membrane Proteins; Mice; Mice, Knockout; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1996 |
Increased non-angiotensin II [125I]CGP 42112 binding in rat carotid artery after balloon injury.
Topics: Angiotensin II; Animals; Autoradiography; Carotid Arteries; Carotid Artery Injuries; Catheterization; Immunohistochemistry; Inflammation; Iodine Radioisotopes; Macrophages; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1996 |
Angiotensin II activates the proinflammatory transcription factor nuclear factor-kappaB in human monocytes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arteriosclerosis; Binding, Competitive; Cell Separation; Consensus Sequence; Humans; Inflammation; Losartan; Lymphocytes; Monocytes; NF-kappa B; NF-kappa B p50 Subunit; Oligonucleotides; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 1999 |
Absence of effect of chronic angiotensin II type 1 receptor blockade on endogenous kinin concentrations-induced paw edema model in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Carrageenan; Dose-Response Relationship, Drug; Edema; Excipients; Inflammation; Kinins; Losartan; Male; Rats; Rats, Wistar; Receptors, Angiotensin | 1999 |
Important role of local angiotensin II activity mediated via type 1 receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthesis in rats.
Topics: Angiotensin II; Animals; Chemokine CCL2; Coronary Vessels; Inflammation; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Superoxides | 2000 |
Angiotensin II (AT(1)) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Coagulation Factors; Blood Pressure; Cell Line; CHO Cells; Coronary Disease; Coronary Vessels; Cricetinae; Extracellular Matrix Proteins; Heart Ventricles; Humans; Inflammation; Integrin alpha4beta1; Integrins; NF-kappa B; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Lymphocyte Homing; RNA, Messenger; Tetrazoles; Thromboplastin; Transcription Factor AP-1; Valine; Valsartan; Vascular Resistance | 2000 |
Effect of bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Bosentan; Cardiomegaly; Fibronectins; Heart; Humans; Hydralazine; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Macrophages; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides; Thromboplastin; Transcription Factor AP-1; Vascular Cell Adhesion Molecule-1 | 2000 |
Workshop: mechanisms and cardiovascular damage in hypertension.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Cardiovascular System; Cell Nucleus; Disease Models, Animal; Hypertension; I-kappa B Kinase; Inflammation; Models, Chemical; Muscle, Smooth, Vascular; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Renin-Angiotensin System; Signal Transduction | 2001 |
AT1 receptor antagonism enhances angiotensin-II-facilitated carrageenan-induced paw edema.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carrageenan; Disease Models, Animal; Drug Synergism; Edema; Extremities; Inflammation; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Vasoconstrictor Agents | 2000 |
Theodore Cooper Lecture: Tissue angiotensin and pathobiology of vascular disease: a unifying hypothesis.
Topics: Angiotensin II; Cardiovascular Diseases; Cell Adhesion Molecules; Cell Communication; Cytokines; Endothelium, Vascular; Enzyme Activation; Homeostasis; Humans; Inflammation; Models, Biological; Nitric Oxide; Peptidyl-Dipeptidase A; Reactive Oxygen Species; Risk Factors | 2001 |
Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cell Division; Chemokine CCL2; Femoral Artery; Inflammation; Interleukin-1; Interleukin-6; Leukocyte Common Antigens; Leukocytes; Macrophages; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Tumor Necrosis Factor-alpha; Tunica Intima; Valine; Valsartan | 2001 |
Release and degradation of angiotensin I and angiotensin II from angiotensinogen by neutrophil serine proteinases.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Binding Sites; Cathepsin G; Cathepsins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Inflammation; Models, Biological; Myeloblastin; Neutrophils; Pancreatic Elastase; Protein Binding; Serine Endopeptidases; Time Factors; Wound Healing | 2002 |
Anti-atherosclerotic efficacy of olmesartan.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arteriosclerosis; Biomarkers; Cholesterol; Cholesterol, Dietary; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; In Vitro Techniques; Inflammation; Lipids; Macaca fascicularis; Male; Olmesartan Medoxomil; Tetrazoles; Treatment Outcome | 2002 |
Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-gamma.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Body Weight; Cell Cycle Proteins; Cell Division; Collagen; DNA; Drug Administration Schedule; Endothelium, Vascular; In Vitro Techniques; Inflammation; Injections, Subcutaneous; Lipids; Male; NF-kappa B; Pioglitazone; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Receptors, Cytoplasmic and Nuclear; Renin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Vascular Cell Adhesion Molecule-1; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
The mediator concept as it developed: histamine and bradykinin.
Topics: Angiotensin II; Bradykinin; Catecholamines; Cyclic AMP; Histamine; Homeostasis; Inflammation; Mast Cells; Prostaglandins; SRS-A | 1977 |
[Visceral and peripheral pharmacoangiography with angiotensin and bradykinin (author's transl)].
Topics: Abscess; Angiography; Angiotensin II; Bradykinin; Celiac Artery; Diagnosis, Differential; Evaluation Studies as Topic; Humans; Inflammation; Kidney Diseases, Cystic; Kidney Neoplasms; Liver Diseases; Neoplasms; Pancreatic Diseases; Prospective Studies; Renal Artery; Splenic Diseases | 1976 |
Inflammation-induced vasodepression detected ex vivo in the isolated perfused hindlegs in mice.
Topics: Anaphylaxis; Angiotensin II; Animals; Carrageenan; Dextrans; Edema; Hindlimb; Inflammation; Male; Mice; Mice, Inbred ICR; Muscles; Norepinephrine; Reference Values; Regional Blood Flow; Vasoconstriction | 1988 |
The involvement of catecholamines and polypeptide hormones in the multihormonal modulation of rat hepatic zinc thionein levels.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Catecholamines; Cyclic AMP; Dexamethasone; Enzyme Activation; Female; Glucagon; Inflammation; Liver; Male; Metallothionein; Phorbol Esters; Protein Kinase C; Protein Kinases; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Turpentine; Type C Phospholipases | 1987 |
Chemotactic response of splenic mononuclear cells to angiotensin II in murine schistosomiasis.
Topics: Angiotensin II; Animals; Chemotaxis, Leukocyte; Inflammation; Lymphocytes; Macrophages; Mice; Mice, Inbred CBA; Neutrophils; Receptors, Angiotensin; Schistosomiasis mansoni; Spleen | 1986 |
Complex effects of antibodies to polypeptide hormones.
Topics: Angiotensin II; Animals; Antibodies; Antigen-Antibody Reactions; Biological Assay; Blood Pressure; Bradykinin; Female; gamma-Globulins; Hypertension; Ileum; In Vitro Techniques; Inflammation; Melanocyte-Stimulating Hormones; Melanocytes; Muscle, Smooth; Peptides; Protease Inhibitors; Rabbits; Radioimmunoassay; Rats; Uterus | 1970 |
Type and course of the inflammatory cellular reaction in acute angiotensin-hypertensive vascular disease in rats.
Topics: Angiotensin II; Animals; Arteries; Biological Transport, Active; Carbon; Cortisone; Female; Fluorescence; Hypertension; Inflammation; Lymphocytes; Monocytes; Phagocytosis; Proteins; Rats | 1970 |
The secondary and tertiary inflammatory cellular reaction in arterioles damaged by acute angiotensin-hypertension in rats.
Topics: Angiotensin II; Animals; Blood Cell Count; Cell Aggregation; Female; Hypersensitivity, Delayed; Hypertension; Inflammation; Leukocytes; Mesenteric Arteries; Norepinephrine; Rats; Time Factors | 1970 |
Evidence for an immunological factor in the hypertensive vascular disease.
Topics: Angiotensin II; Animals; Female; Hypersensitivity, Delayed; Hypertension; Inflammation; Lymphocytes; Mesenteric Arteries; Rats | 1971 |
Adrenal corticosteroids--physiological considerations.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Androgens; Angiotensin II; Blood Cells; Connective Tissue; Glucocorticoids; Humans; Hydrocortisone; Hypersensitivity; Inflammation; Juxtaglomerular Apparatus; Lymphoid Tissue; Mineralocorticoids; Renin; Sodium Chloride; Stress, Physiological; Water | 1972 |
[A chemically and pharmacologically novel antagonist of physiopathologically important amines, kinins and kinin-forming factors].
Topics: Acetylcholine; Anaphylaxis; Angiotensin II; Animals; Antimetabolites; Arachidonic Acids; Autacoids; Bradykinin; Chemistry, Organic; Drug Antagonism; Epinephrine; Glucose; Glycosides; Histamine; In Vitro Techniques; Inflammation; Kinins; Mice; Muscle, Smooth; Organic Chemistry Phenomena; Peroxides; Rabbits; Rats; Serotonin; Trypsin; Vasopressins; Venoms | 1967 |