angiotensin ii has been researched along with Hypertrophy in 381 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (9.97) | 18.7374 |
| 1990's | 101 (26.51) | 18.2507 |
| 2000's | 129 (33.86) | 29.6817 |
| 2010's | 96 (25.20) | 24.3611 |
| 2020's | 17 (4.46) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C; Li, G; Liu, W; Long, X; Qiu, Z; Shen, C; Shi, B; Wang, Y; Zhang, Y; Zhao, R; Zhuang, S | 1 |
| Bai, Y; Chen, C; Gao, Z; Jiang, X; Meng, Y; Zhang, X; Zheng, C | 1 |
| Chen, Z; Shui, X; Tang, L; Wang, M; Xiong, Z; Yu, X; Zhu, C | 1 |
| Cheng, G; Li, X; Liao, S; Lu, W; Wu, J; Zhu, H | 1 |
| Ding, Y; Gu, Y; Li, Y; Shang, Z; Zhang, X | 1 |
| Fan, P; Guo, Y; Tang, B; Ye, Y; Zhang, J; Zhu, J | 1 |
| Du, Z; Hao, Y; Li, W; Liang, Z; Liu, Y; Tao, Y; Wang, J; Yan, X; Yang, Y; Yu, J; Yuan, Y; Zhao, X | 1 |
| Du, Y; Du, Z; Hu, C; Jiao, X; Li, F; Li, L; Lv, Q; Qin, Y; Sun, Q; Wang, Y; Yu, H; Zhang, J; Zhang, X | 1 |
| Budhram-Mahadeo, VS; Clark, JE; Heads, RJ; Maskell, LJ; Mele, L; Stuckey, DJ | 1 |
| Balducci, V; Cerbai, E; Dini, L; Diolaiuti, L; Gencarelli, M; Ghionzoli, M; Laurino, A; Messineo, A; Mugelli, A; Raimondi, L; Sartiani, L; Spinelli, V | 1 |
| Ahmed, MS; Attramadal, H; Aukrust, P; Holt, MF; Lien, E; Louwe, MC; Mollnes, TE; Nilsson, PH; Schjalm, C; Shahini, N; Yndestad, A; Øgaard, JDS | 1 |
| Cheng, H; Gao, Y; He, M; Li, J; Sun, N; Wu, Q; Yang, Q; Zheng, X; Zhou, Y | 1 |
| Gao, L; Guo, S; Li, Y; Liu, Y; Shen, J; Shi, Q; Xiao, F; Xing, S; Yang, F; Zhang, W; Zhao, L | 1 |
| Choi, JW; Hwang, KC; Hyun, SA; Jeong, S; Kim, SW; Lee, BS; Lee, CY; Lee, S; Lim, S; Park, HK | 1 |
| Bereshchenko, O; Berrino, L; Bruscoli, S; Cappetta, D; Cianflone, E; Cozzolino, A; De Angelis, A; Flamini, S; Gagliardi, A; Rafaniello, C; Riccardi, C; Ricci, E; Ronchetti, S; Rossi, F; Urbanek, K | 1 |
| Anand-Srivastava, MB; Jain, A; Srivastava, AK; Truong, V | 1 |
| de Gannes, M; Koch, SE; Puga, A; Rubinstein, J | 1 |
| Asmadi, AY; Jalil, J; Kamisah, Y; Siti, HN | 1 |
| Chen, C; Feng, J; Guo, Y; Qin, Q; Ren, B; Yang, N | 1 |
| Cohen, IS; Jiang, YP; Kim, JH; Lin, RZ; Mathias, RT | 1 |
| Asante, S; Breeden, J; Buehler, T; Cantilena, A; Chen, L; Dawn, B; Girgis, M; Mahmoudi, SM; Samanta, A; Vincent, RJ; Xuan, YT; Zhao, L | 1 |
| Anand-Srivastava, MB; Hossain, E | 1 |
| Shen, Z; Wang, X; Yang, K; Zhang, Z | 1 |
| Sun, Y; Wang, J; Yan, B | 1 |
| Chen, D; Chen, F; Jin, L; Pan, T; Su, Y; Wan, M; Wang, X; Xu, Y; Ye, J; Zhang, H; Zhang, Y | 1 |
| Bethmann, D; Gekle, M; Hünerberg, M; Mildenberger, S; Rabe, S; Schreier, B; Wickenhauser, C | 1 |
| Hu, Q; Hu, Y; Li, M; Tian, H; Yang, Y; Yu, D; Zhang, P | 1 |
| Lassègue, B; Ma, J; San Martín, A; Sutliff, RL; Weiss, D; Williams, HC | 1 |
| Choi, MJ; Hwang, JS; Kang, ES; Lee, GH; Lee, WJ; Lim, DS; Paek, KS; Seo, HG | 1 |
| Peng, L; Yan, K; Zhang, H; Zheng, N; Zhou, K | 1 |
| Abraham, D; Acar, E; Costantino, S; Gonçalves, IF; Hallström, S; Hamza, O; Kiss, A; Klein, KU; Paneni, F; Podesser, BK; Szabo, PL; Tretter, EV; Trojanek, S | 1 |
| Gao, T; Wang, F; Wang, J; Xie, M; Xue, J; Ye, H | 1 |
| Cho, HW; Cho, S; Jeong, J; Lim, J; Lim, S; Park, S; Seo, M; Woo, KW | 1 |
| Gao, Y; Ma, ZC; Tan, HL; Wang, J; Wang, NN; Wang, YG | 1 |
| Beauval, JB; de Bonnecaze, G; Doumerc, N; Game, X; Malavaud, B; Mansouri, A; Rischmann, P; Rouvellat-Terrade, P | 1 |
| Bers, DM; Bossuyt, J; Chuprun, JK; Gao, E; Gold, JI; Hullmann, J; Koch, WJ; Lee, L; Martini, JS; Rabinowitz, JE; Tilley, DG | 1 |
| Bourne, AM; Eguchi, A; Eguchi, S; Elliott, KJ; Hinoki, A; Hurlin, PJ; Takaguri, A; Takayanagi, T | 1 |
| Abhilash, PA; Prathapan, A; Raghu, KG; Vineetha, VP | 1 |
| Hua, W; Yan, QL; Yu, LZ | 1 |
| Cheng, M; Han, L; Li, M; She, T; Shi, C; Yu, L | 1 |
| Kim, MS; Lee, BH; Lee, JH; Mun, J; Oh, KS; Ryu, SY | 1 |
| Abdul-Ghani, M; Brunette, S; Dick, SA; Fernando, P; Megeney, LA; Putinski, C; Stiles, R | 1 |
| Doyon, P; Servant, MJ; van Zuylen, WJ | 1 |
| Azuma, K; Azushima, K; Dejima, T; Kanaoka, T; Kobayashi, R; Maeda, A; Matsuda, M; Ohsawa, M; Tamura, K; Umemura, S; Uneda, K; Wakui, H; Yamashita, A | 1 |
| Balligand, JL; Beauloye, C; Belge, C; Bertrand, L; Dessy, C; Dubois-Deruy, E; Esfahani, H; Götz, KR; Hamelet, J; Hammond, J; Herijgers, P; Hilfiker-Kleiner, D; Iaccarino, G; Jnaoui, K; Langin, D; Lobysheva, I; Manoury, B; Markl, A; Nikolaev, VO; Pouleur, AC; Tavernier, G; Vanderper, A | 1 |
| Bi, A; Chen, D; Gao, M; Guo, Y; Liu, J; Luo, L; Rui, B; Sun, S; Yang, T; Yin, Z; Zhao, N | 1 |
| Caldiz, CI; Cingolani, HE; Correa, MV; de Cingolani, GE; Ennis, IL; Nolly, MB | 1 |
| Du, M; Gao, L; Huang, D; Huang, K; Wang, B; Wang, WS; Yang, L | 1 |
| Chen, J; Chen, Y; Gu, S; Ma, R; Ma, X; Xiao, X; Yao, Z; Zhang, W | 1 |
| Chen, K; Chen, Y; Fan, GC; Gao, L; Gong, H; Jiang, DS; Li, H; Liu, PP; Liu, Y; Peng, J; Yang, Q; Zhang, XD; Zhang, XF; Zhang, Y; Zhou, H; Zou, Y | 1 |
| Golledge, J; Krishna, SM; Liu, D; Moran, CS; Seto, SW | 1 |
| Burger, D; Chibale, K; Mahajan, A; Reudelhuber, TL; Sturrock, ED; Touyz, RM | 1 |
| Brain, SD; de Winter, P; Dessapt-Baradez, C; Fernandes, E; Gnudi, L; Heads, RJ; King, R; Kodji, X; Marshall, N; Outzen, E; Pozsgai, G; Sams, A; Shah, AM; Siow, RC; Smillie, SJ | 1 |
| Anand-Srivastava, MB; Atef, ME | 1 |
| Han, F; Lou, XF; Lu, YM; Sun, MM; Wang, P; Xie, YY; Zhang, BY; Zhang, C | 1 |
| Aranega, AE; Franco, D; Hernandez-Torres, F | 1 |
| Drummond, GR; Dusting, GJ; Fender, AC; Pavic, G; Ritchie, RH | 1 |
| Akamine, EH; Barreto-Chaves, ML; Carvalho, MH; Ceravolo, GS; Chopard, RP; Costa, TJ; Fernandes, DC; Fortes, ZB; Jordão, MT; Laurindo, FR; Montezano, AC; Takano, AP; Tostes, RC; Touyz, RM | 1 |
| Black, MJ; Blaschke, F; Cox, TC; Drenckhahn, JD; Fischer, R; Heinecke, K; Hennig, M; Heuser, A; Langner, P; Skole, F; Spallek, B; Strasen, J; Thierfelder, L; Yin, KV | 1 |
| Che, W; Guo, H; Hou, L; Jie, Q; Li, G; Liu, B; The, E; Wang, D; Wei, Y | 1 |
| Davisson, RL; Eguchi, S; Elliott, KJ; Forrester, SJ; Fukuda, Y; Kawai, T; Obama, T; Park, JY; Takayanagi, T; Tilley, DG; Tsuji, T | 1 |
| Cai, Y; Chen, M; Chen, Y; Jiang, J; Ling, Y; Pan, S; Shan, L; Shou, Q; Tu, J; Wang, D; Yang, W | 1 |
| Isobe, M; Ogawa, M; Suzuki, J; Watanabe, R; Zempo, H | 1 |
| Deng, KQ; Gao, L; Jiang, DS; Jiang, X; Li, H; Luo, Y; Zhang, P; Zhang, XF; Zhao, GN; Zhu, X | 1 |
| Li, Z; Xing, L | 1 |
| Hashimoto, T; Ikeda, Y; Imaizumi, A; Komuro, I; Kumagai, H; Morita, H; Motozawa, Y; Nagai, R; Nakao, T; Nakayama, A; Sumida, T; Takahashi, T; Yamaguchi, T | 1 |
| Baumbach, GL; Chan, SL; Houwen, FK; Umesalma, S | 1 |
| Del Valle-Mondragón, L; Gallardo-Ortíz, IA; López-Guerrero, JJ; López-Sánchez, P; Rodríguez-Hernández, SN; Touyz, RM; Villalobos-Molina, R | 1 |
| Xiaoyuan, S; Xinzhong, H | 1 |
| Chang, YM; Chen, RJ; Chen, YS; Ho, TJ; Huang, CY; Lin, SL; Padma, VV; Tsai, CC; Tsai, CT; Yeh, YL | 1 |
| Guan, H; Mei, Y; Mi, Y; Xu, Y; Zhao, L | 1 |
| Cho, SN; Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Kim, HS; Lin, MQ; Ryu, Y; Yu, SY | 1 |
| Al Ghouleh, I; Bisello, A; Cifuentes-Pagano, ME; Friedman, PA; Gorelova, A; Henrich Amaral, J; Mamonova, T; Meijles, DN; Mutchler, S; Pagano, PJ; Rodríguez, AI; Sahoo, S; Song, GJ; Zhang, Q | 1 |
| Chen, L; Cheng, G; Huang, X; Liu, Z; Peng, H; Shi, R; Xu, Q; Yang, T; Yang, W; Yu, Z; Zhang, G | 1 |
| Han, Y; Li, Y; Liu, D; Liu, H; Liu, M; Liu, Y; Peng, C; Song, H; Tian, X; Yan, C; Zhang, J; Zhang, Q; Zhang, X; Zhang, Y | 1 |
| Block, K; Eid, A; Gorin, Y; Griendling, KK; Lee, DY; Wittrant, Y | 1 |
| Feliers, D; Ghosh Choudhury, G; Kasinath, BS; Lee, MJ; Mariappan, MM; Sataranatarajan, K | 1 |
| Feng, J; Li, SS; Liang, QS; Zheng, Z | 1 |
| Cai, L; Hein, DW; Li, X; Marshall, JP; Prabhu, SD; Xiang, X; Zhou, G | 1 |
| Böhm, M; Laufs, U; Lenski, M; Stuck, BJ | 1 |
| Feng, J; Zheng, Z | 1 |
| Chen, SY; Deng, SX; Li, D; Li, YJ; Liao, DF; Qin, XP; Ren, JF; Tian, HH; Zeng, SY; Zheng, YB | 1 |
| Chen, S; Doss, MX; Hescheler, J; Hübner, N; Kamisetti, N; Liang, H; Obernier, K; Pfannkuche, K; Potta, SP; Sachinidis, A; Schulz, H; Winkler, J | 1 |
| Anderson, WP; Bertram, JF; Cullen-McEwen, LA; Denton, KM; Evans, RG; Fitzgerald, SM; Kett, MM; Shweta, A | 1 |
| Curl, CL; Delbridge, LM; Huggins, CE; McLennan, PL; Patel, R; Pedrazzini, T; Pepe, S; Theiss, ML | 1 |
| Lee, KS; Lee, S; Lim, HJ; Park, HY; Park, JH | 1 |
| Aoka, Y; Hagiwara, N; Kasanuki, H; Kawana, M; Nagashima, H; Sakurabayashi-Kitade, S | 1 |
| Ge, Z; Geng, J; Kang, W; Liu, G; Sun, Y; Wang, W; Zhang, Y; Zhao, Z | 1 |
| Anegawa, T; Hirooka, Y; Ikeda, A; Imaizumi, T; Kai, H; Kajimoto, H; Kato, S; Koga, M; Kudo, H; Mifune, H; Mori, T; Takayama, N; Yasuoka, S | 1 |
| Lu, Y; Yang, S | 1 |
| Hu, SJ; Li, L; Ye, Y | 1 |
| Arany, ZP; Hofmann, F; Itoh, H; Miyashita, K; Nakao, K; Sawada, N; Sone, M; Tsujimoto, H; Yamahara, K | 1 |
| Chang, B; Cui, XL; Myatt, L | 1 |
| Born, W; Brain, SD; Clark, N; Fischer, JA; Husmann, K; Keeble, J; Liang, L; Poston, R; Pozsgai, G; Shah, A; Siow, R; Tam, CW | 1 |
| Ahmad, M; Alexander, RW; Hilenski, L; Ma, M; Nazarewicz, RR; Patrushev, N; Salazar, G; San Martin, A; Ushio-Fukai, M; Xiong, S | 1 |
| Anderson, ME; Grumbach, IM; Gupta, AK; Li, H; Li, W; Mohler, PJ | 1 |
| Ge, Z; Geng, J; Kang, W; Su, G; Wang, L; Wang, W; Zhang, Y; Zhao, Z | 1 |
| Cui, CC; Huang, C; Li, Y; Zhao, YH | 1 |
| Almeida, J; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Nadu, AP; Santos, RA; Vieira, RL | 1 |
| Bosch, RJ; Izquierdo, A; López-Luna, P; Ortega, A; Romero, M | 1 |
| Fox, DA; Kashihara, N; Morita, Y; Sakuta, T; Satoh, M | 1 |
| Claycomb, WC; Ladurner, AG; Rosenthal, N; Santini, MP; Vinciguerra, M | 1 |
| An, J; Chen, L; Chen, YJ; Han, SX; He, GM; Ning, YY; Wang, T; Wen, FQ; Xu, D; Yang, T; Zhang, SF; Zhang, XH | 1 |
| Chiu, CZ; Chung, TH; Shyu, KG; Wang, BW | 1 |
| Bachschmid, MM; Cohen, RA; Ho, YS; Maitland-Toolan, KA; Matsui, R; Xu, S | 1 |
| Gao, Y; Liu, XH; Yu, DQ | 1 |
| Arribas, I; Bosch, RJ; Bover, J; Esbrit, P; Izquierdo, A; Ortega, A | 1 |
| Chen, H; Gao, P; Li, L; Liang, C; Liu, D; Lv, X; Wei, Y; Xu, T; Zhang, H; Zheng, W | 1 |
| Alcorn, D; Anderson, WP; Bertram, JF; Kett, MM | 1 |
| Carlile-Klusacek, M; Eguchi, K; Eguchi, S; Hinoki, A; Kimura, K; Rizzo, V; Shirai, H; Takaguri, A; Yang, B | 1 |
| Flores-Muñoz, M; Haggerty, C; Milligan, G; Nicklin, SA; Smith, NJ | 1 |
| Akazawa, S; Bourne, AM; Eguchi, S; Elliott, KJ; Kono, R; Okuno, Y; Takaguri, A; Utsunomiya, H | 1 |
| Aizawa, Y; Giridharan, VV; Harima, M; Kodama, M; Lakshmanan, AP; Sari, FR; Soetikno, V; Thandavarayan, RA; Watanabe, K | 1 |
| Gao, MH; Li, B; Ren, SR; Zhang, B; Zhang, L | 1 |
| Bahrami, AJ; Daum, G; Gunaje, JJ; Mahoney, WM; Schwartz, SM | 1 |
| Akizawa, T; Hirai, Y; Iyoda, M; Kuno, Y; Shibata, T | 1 |
| Fujita, Y; Hara, T; Hitomi, H; Kaifu, K; Kiyomoto, H; Kobori, H; Kohno, M; Moriwaki, K; Nakano, D; Nishiyama, A; Sofue, T | 1 |
| Chang, L; Li, Y; Liu, J; Wang, M; Wang, Y; Yang, R; Zhang, H | 1 |
| Griendling, KK; Hitomi, H; Lassègue, B; Mehta, PK; San Martin, A; Seidel-Rogol, B; Taniyama, Y | 1 |
| Cheng, YQ; Jia, Y; Li, XH; Liu, Y; Wang, XQ; Zhang, HG; Zhou, JZ | 1 |
| Dong, XL; Du, J; Guo, S; Li, HH; Tang, CS; Wang, HX; Yang, H; Zeng, XJ; Zhang, LK | 1 |
| Bourne, AM; Eguchi, K; Eguchi, S; Elliott, KJ; Kimura, K; Takaguri, A; Takayanagi, T | 1 |
| Gul, R; Kim, SH; Kim, UH; Shawl, AI | 1 |
| Calderon, LE; Eberhard, W; Gong, MC; Guo, Z; Liu, S; Su, W; Xie, Z | 1 |
| Fujisawa, G; Iwazu, Y; Kimura, M; Kobayashi, E; Kobayashi, T; Kusano, E; Masuda, T; Murakami, T; Muto, S; Nonaka-Sarukawa, M; Sasaki, N; Shimada, K; Shinohara, M; Watanabe, Y | 1 |
| Benkhoff, S; Brandes, RP; Dimmeler, S; Kosowski, J; Kruse, C; Luedike, P; Michaelis, UR; Mieth, A; Pliquett, R; Schröder, K; Shah, AM; Weissmann, N; Zhang, M | 1 |
| Chiu, HL; Chuang, CF; Chuang, ST; Kuo, YH; Su, MJ; Weng, YC | 1 |
| Javadov, S; Karmazyn, M; Kilic, A; Rajapurohitam, V | 1 |
| Dong, LH; Gao, M; Han, M; Liu, G; Lv, P; Miao, SB; Shu, YN; Wang, XJ; Wang, YC; Xie, XL; Yin, YJ | 1 |
| Chen, AL; Chen, MS; Dong, Q; He, ZC; Liu, QC; Ou, CW | 1 |
| Briet, M; Schiffrin, EL | 1 |
| Guo, W; Liao, YL; Lv, R; Wei, HC; Zhang, C | 1 |
| Arai, M; Koitabashi, N; Kurabayashi, M; Matsui, H; Sunaga, H; Takizawa, T; Tanaka, C; Yokoyama, T | 1 |
| Cheng, C; Li, A; Liu, B; Liu, S; Pan, W; Wang, L; Xiong, L; Zhong, Y | 1 |
| Ruwhof, C; Schrier, PI; van der Laarse, A; van der Valk-Kokshoorn, LJ; van Wamel, AJ | 1 |
| Chaqour, B; Chichester, P; Han, JS; Horan, P; Levin, R; Macarak, E; Whitbeck, C | 1 |
| Dirsch, VM; Griendling, KK; Haider, UG; Sorescu, D; Vollmar, AM | 1 |
| Braz, JC; Bueno, OF; De Windt, LJ; Glascock, BJ; Kimball, TF; Molkentin, JD; Wilkins, BJ | 1 |
| Adler, SG; Kang, SW; Kim, YS; Lanting, L; Nadler, JL; Natarajan, R; Reddy, MA; Rossi, J; Shahed, A | 1 |
| Liu, WB; Rao, MR; Zhang, XW | 1 |
| Giraud, GD; Maylie, JG; Stork, PJ; Sundgren, NC; Thornburg, KL | 1 |
| Jankowski, M; Liu, J; Pagano, PJ; Yang, F; Yang, XP | 1 |
| Schiffrin, EL; Touyz, RM | 1 |
| Jablonski, K; Reinking, R; Schroeder, R; Shankland, SJ; Stahl, RA; Wolf, G | 1 |
| Cifuentes, ME; Pagano, PJ | 1 |
| Hong, HK; Kim, BC; Lee, HS; Park, SY; Song, CY | 1 |
| Ciccone, E; Deelman, L; Hajnoczky, G; Henning, R; Hu, T; Kurz, B; Ma, X; Madesh, M; Sharma, K; Siva, S; Wang, L; Zhu, Y | 1 |
| Miao, CY; Su, DF; Yuan, WJ; Zhang, LM | 1 |
| Adam, AG; Jaimes, EA; Raij, L; Zhou, MS | 1 |
| Boner, G; Erman, A; Gafter, U; Natif, N; Sclarovsky-Benjaminov, F; Sulkes, J; Van Dijk, DJ | 1 |
| Kadonosono, K; Kamei, J; Okuda, K; Tanaka, S; Yamakawa, T | 1 |
| Arend, A; Aunapuu, M; Ots, M; Pechter, U; Suuroja, T | 1 |
| Chan, P; Chen, JJ; Chen, YL; Cheng, CF; Cheng, TH; Huang, MT; Lin, H; Liu, JC; Shih, NL | 1 |
| Wenzel, UO; Wolf, G | 1 |
| Remuzzi, G; Schieppati, A | 1 |
| Karmazyn, M; Xia, Y | 1 |
| Hoofnagle, MH; Owens, GK; Yoshida, T | 1 |
| Abboud, HE; Bhandari, B; Choudhury, GG; Gorin, Y; Kim, NH; Ricono, JM; Wagner, B | 1 |
| Aartsen, WM; De Mey, JG; Fazzi, GE; Hilgers, RH; Schiffers, PM; Smits, JF | 1 |
| Kurabayashi, M; Manabe, I; Nagai, R; Shindo, T; Suzuki, T | 1 |
| Chen, Q; Liu, BC; Luo, DD; Ma, KL; Ruan, XZ; Sun, J | 1 |
| Díez, J | 1 |
| Michel, JB | 1 |
| Bertram, JF; Dilley, RJ; Rizkalla, B | 1 |
| Arima, N; Fujii, T; Imaizumi, T; Kato, S; Morimatsu, M; Okamoto, K | 1 |
| Alexander, RW; Hilenski, LL; Ushio-Fukai, M; Zuo, L | 1 |
| Egashira, K; Hiasa, K; Ishibashi, M; Takeshita, A; Tan, C; Zhao, Q | 1 |
| Liu, J; Oja-Tebbe, N; Ormsby, A; Pagano, PJ | 1 |
| Griendling, KK; Harrison, DG; Laude, K; Lyle, AN; Mellis, AM; Rocic, P; Weber, DS | 1 |
| Chou, MY; Chueh, PJ; Huang, CY; Kuo, WW; Tseng, CT; Yang, JJ | 1 |
| Chen, L; Chen, Q; Fan, LM; Liu, BC; Liu, H; Sun, J | 1 |
| Black, MJ; Jones, ES; Widdop, RE | 1 |
| Allessie, M; Blaauw, Y; Eijsbouts, S; Neuberger, HR; Schotten, U; van Hunnik, A; Verheule, S | 1 |
| Bescond, J; Delwail, A; Fredj, S; Lecron, JC; Louault, C; Potreau, D | 1 |
| Bluyssen, HA; Braam, B; Ishola, DA; Joles, JA; Koomans, HA; Wesseling, S | 1 |
| Aitkenhead, M; Levin, ER; Pedram, A; Razandi, M | 1 |
| Alexander, RW; Hilenski, L; Ikeda, S; Patrushev, N; Ushio-Fukai, M; Zuo, L | 1 |
| Cohen, RA; Handy, DE; Hayes, A; Leopold, JA; Loscalzo, J; Maitland, KA; Matsui, R; Xu, S | 1 |
| Malik, KU; Parmentier, JH; Pavicevic, Z | 1 |
| Chakrabarti, S; Javadov, S; Karmazyn, M; Purdham, DM; Rajapurohitam, V; Zeidan, A | 1 |
| Alexander, RW; Ikeda, S; Patrushev, NA; Tojo, T; Ushio-Fukai, M; Zuo, L | 1 |
| Dikalova, A; Griendling, KK; Owens, GK; Taylor, WR; Zhang, Y | 1 |
| Cheng, G; Clempus, R; Dikalov, S; Dikalova, A; Griendling, KK; Lambeth, JD; Lassègue, B; Lyle, A; McCoy, J; Owens, GK; San Martin, A; Schmidt, HH; Taylor, WR; Weber, DS; Weiss, D | 1 |
| Chen, L; Huang, HQ; Liu, BC; Liu, DG; Liu, H; Ma, KL; Sun, J; Zhang, XL | 1 |
| Amiri, F; Diep, QN; Neves, MF; Schiffrin, EL; Virdis, A | 1 |
| Calò, LA | 1 |
| Hajjar, R; Kaprielian, R; Lebeche, D | 1 |
| Chen, J; Chen, JK; Harris, RC; Neilson, EG | 1 |
| Davisson, RL; Dunlay, SM; Engelhardt, JF; Hingtgen, SD; Peek, AS; Sharma, RV; Tian, X; Wu, Y; Yang, J | 1 |
| Hwang, GS; Koo, HN; Lee, BH; Oh, KS; Seo, HW; You, KH | 1 |
| Alvarez, MJ; Arribas, I; Bosch, RJ; Esbrit, P; Guitiérrez-Tarrés, MA; Izquierdo, A; López-Luna, P; Ortega, A; Romero, M | 1 |
| Bennett, MR; Brown, MJ; Foo, RS; Siow, RC | 1 |
| Brailoiu, E; Dempsey, PJ; Eguchi, K; Eguchi, S; Frank, GD; Higuchi, S; Nakashima, H; Ohtsu, H; Suzuki, H | 1 |
| Lopaschuk, GD | 1 |
| Liu, ZX; Qin, J | 1 |
| Dhobale, S; Eguchi, K; Eguchi, S; Frank, GD; Higuchi, S; Motley, ED; Ohtsu, H; Suzuki, H | 1 |
| Tu, JW; Tu, X; Wang, JM; Wang, Y; Yang, Y | 1 |
| Im, CN; Seo, JS; Zheng, Y | 1 |
| Chan, HW; Hannan, RD; Jenkins, A; Pipolo, L; Smith, NJ; Thomas, WG | 1 |
| Iijima, T; Ito, H; Murakami, M; Ohba, T; Ono, K; Radovanovic, M; Takahashi, Y; Watanabe, H | 1 |
| Burke, SL; Evans, RG; Head, GA; Lambert, GW | 1 |
| Coles, B; Fielding, CA; Jones, SA; O'Donnell, VB; Rose-John, S; Scheller, J | 1 |
| Chappell, MC; Gallagher, PE; Groban, L; Pendergrass, KD; Pirro, NT; Yamaleyeva, LM | 1 |
| Bressenot, A; Challande, P; Gao-Li, J; Gardner, H; Kakou, A; Labat, C; Lacolley, P; Li, Z; Louis, H; Regnault, V; Thornton, SN | 1 |
| Ha, CH; Hausser, A; Jin, ZG; McKinsey, TA; Olson, EN; Pfizenmaier, K; Wang, W; Wong, C; Xu, X | 1 |
| Busk, PK; Haunsø, S; Hinrichsen, R | 1 |
| Didion, SP; Faraci, FM; Johnson, AW; Kinzenbaw, DA; Schrader, LI | 1 |
| Alfarano, C; Cerbai, E; Mannucci, E; Mugelli, A; Nediani, C; Raimondi, L; Sartiani, L | 1 |
| Graciano, ML; Jackson, K; Kobori, H; Navar, LG; Nishiyama, A; Ortiz, RM; Prieto-Carrasquero, MC; Seth, DM | 1 |
| He, XX; Liu, Q; Yang, GT; Zhou, DX | 1 |
| Brors, B; Frank, D; Frey, N; Hanselmann, C; Katus, HA; Kuhn, C; Lüdde, M | 1 |
| Alenina, N; Bader, M; Feng, X; Li, PF; Murtaza, I; Prabhakar, BS; Wang, HX | 1 |
| Dempsey, PJ; Eguchi, K; Eguchi, S; Frank, GD; Higuchi, S; Hinoki, A; Inagami, T; Nakashima, H; Ohtsu, H; Reyland, ME; Sanjay, A; Shirai, H | 1 |
| Baud, L; Bellocq, A; de Castro Keller, A; Haymann, JP; Letavernier, E; Mesnard, L; Perez, J | 1 |
| Alibin, CP; Anderson, HD; Kopilas, MA | 1 |
| Colella, M; Grisan, F; Pozzan, T; Robert, V; Thomas, AP; Turner, JD | 1 |
| Johnson, IM; Kale, S; Majumdar, G; Raghow, R | 1 |
| Ecelbarger, CM; Hu, X; Madala Halagappa, VK; Riazi, S; Tiwari, S | 1 |
| Brailoiu, E; Eckhart, AD; Eguchi, K; Eguchi, S; Frank, GD; Higuchi, S; Hinoki, A; Ohtsu, H; Shirai, H; Suzuki, H | 1 |
| Leenen, FH; Liang, B | 1 |
| Gul, R; Im, MJ; Kim, BJ; Kim, SJ; Kim, SY; Kim, UH; Park, KH | 1 |
| Bohr, DF; Webb, RC; Winquist, RJ | 1 |
| Korner, PI | 1 |
| Bing, RF; Mistry, M; Swales, JD; Thurston, H | 1 |
| Becker, CH; Engler, E; Matthias, D; Schmidt, R | 1 |
| Folkow, B; Lever, AF | 1 |
| Fukuo, K; Inoue, T; Jiang, B; Koh, E; Morimoto, S; Nabata, T; Ogihara, T; Rakugi, H; Tomita, J | 1 |
| Hautmann, M; Haystead, TA; Hershey, JC; Owens, GK; Rothblum, LI; Thompson, MM | 1 |
| Bertram, JF; Black, MJ; Campbell, GR; Campbell, JH | 1 |
| Lee, LK; Lovett, DH; Meyer, TW; Pollock, AS | 1 |
| Erdjument-Bromage, H; Marks, AR; Patton, WF; Taubman, MB; Tempst, P | 1 |
| Mondorf, U; Schoeppe, W; Stahl, RA; Wolf, G; Zahner, G | 1 |
| Bhandaru, S; Claycomb, WC; Cook, JL; Giardina, JF; Ré, RN | 1 |
| Higaki, J; Kawaguchi, N; Kobayashi, R; Mikami, H; Nagano, M; Nakamura, F; Ogihara, T; Onishi, S | 1 |
| Bertram, JF; Black, MJ; Bobik, A; O'Sullivan, JB | 1 |
| Belloni, AS; Markowska, A; Mazzocchi, G; Musajo, FG; Nussdorfer, GG; Rebuffat, P; Rocco, S | 1 |
| Fujita, T; Hatakeyama, H; Miyamori, I; Takeda, R; Takeda, Y; Yamamoto, H | 1 |
| Gottardo, G; Mazzocchi, G; Musajo, FG; Nowak, KW; Nussdorfer, GG; Rebuffat, P; Tortorella, C | 1 |
| Eydelloth, RS; Hubert, MF; Keenan, KP; Molon-Noblot, S; Owen, RA; Siegl, PK | 1 |
| Kent, KC; Mallette, SA; Mii, S; Ware, JA | 1 |
| Higaki, J; Mikami, H; Morishita, R; Ogihara, T; Rakugi, H; Yu, H | 1 |
| Fogo, A | 1 |
| Alexander, RW; Griendling, KK; Minieri, CA; Ollerenshaw, JD | 1 |
| Tedgui, A | 1 |
| Izumo, S; Sadoshima, J; Slayter, HS; Xu, Y | 1 |
| Gonzales, N; Lanting, L; Nadler, J; Natarajan, R | 1 |
| Wolf, G | 1 |
| Lever, AF | 1 |
| Hostetter, TH; Rosenberg, ME; Smith, LJ | 1 |
| Black, MJ; Campbell, GR; Campbell, JH | 1 |
| Deng, LY; Larochelle, P; Schiffrin, EL | 1 |
| Anderson, PW; Do, YS; Hsueh, WA | 1 |
| Neilson, EG; Wolf, G | 2 |
| Gibbons, GH; Koibuchi, Y; Lee, WS; Pratt, RE | 1 |
| Heidland, A; Ling, H; Schaefer, L; Schaefer, RM; Schnittler, HJ; Vamvakas, S | 1 |
| Berk, BC; Bernstein, KE; Duff, JL; Marrero, MB; Paxton, WG; Schieffer, B | 1 |
| Adachi, S; Akimoto, H; Fujisaki, H; Hata, M; Hiroe, M; Ito, H; Lin, M; Marumo, F; Tanaka, M | 1 |
| Heidland, A; Ling, H; Paczek, L; Vamvakas, S | 1 |
| Benessiano, J; Caputo, L; Duriez, M; Henrion, D; Heymes, C; Levy, BI; Poitevin, P; Samuel, JL | 1 |
| Cooper, ME; Komers, R; Rumble, JR | 1 |
| Fickova, M; Kral, JG; Macho, L; Zelezna, B; Zorad, S | 1 |
| Fukui, T; Griendling, KK; Ishizaka, N; Ushio-Fukai, M; Zafari, AM | 1 |
| Rosendorff, C | 2 |
| Du, Y; Wang, DH; Yao, A | 1 |
| Stahl, RA; Wolf, G | 1 |
| Andersson, KE; Pandita, RK; Persson, K; Waldeck, K | 1 |
| Komuro, I; Kurihara, H; Kurihara, Y; Yamazaki, T; Yazaki, Y | 1 |
| Choi, KH; Han, DS; Kang, SW; Lee, HY | 1 |
| Birt, PC; Zimmerman, BG | 1 |
| Brouwers-Ceiler, DL; De Mey, JG; Nelissen-Vrancken, HJ; Smits, JF | 1 |
| Caputo, L; Faggin, E; Levy, BI; Marotte, F; Poitevin, P; Rappaport, L; Sabri, A; Samuel, JL | 1 |
| Angulo, J; Llergo, JL; López-Novoa, JM; Peiró, C; Rodríguez-López, A; Rodríguez-Mañas, L; Sánchez-Ferrer, CF | 1 |
| Barton, M; d'Uscio, LV; Lüscher, TF; Moreau, P; Shaw, S; Takase, H | 1 |
| Wolf, G; Ziyadeh, FN | 1 |
| Black, MJ; Bobik, A; Kanellakis, P | 1 |
| Angulo, J; Llergo, JL; Marín, J; Peiró, C; Rodríguez-Mañas, L; Sánchez-Ferrer, CF | 1 |
| Harada, M; Igaki, T; Itoh, H; Kuwahara, K; Masuda, I; Miyamoto, Y; Nakagawa, O; Nakao, K; Ogawa, E; Ogawa, Y; Saito, Y; Tanaka, I; Yamashita, J; Yoshimasa, T | 1 |
| Egido, J; Ruiz-Ortega, M | 1 |
| Benetos, A; Duriez, M; Lacolley, P; Levy, BI; Safar, ME; Taillard, F | 1 |
| Azuma, J; Azuma, M; Baba, A; Schaffer, SW; Taira, K; Takahashi, K; Yamamoto, I | 1 |
| Borg, TK; Carver, W; Fu, L; Price, RL; Simpson, DG; Terracio, L; Zhao, J | 1 |
| Eto, T; Imamura, T; Kangawa, K; Kato, J; Kitamura, K; Koiwaya, Y; Kuwasako, K; Tsuji, T; Tsuruda, T | 1 |
| Best, CF; Coffman, TM; Ito, M; Madsen, K; Maeda, N; Oliverio, MI; Smithies, O | 1 |
| Csiky, B; Simon, G | 1 |
| Angulo, J; López-Novoa, JM; Marín, J; Peiró, C; Regadera, J; Rodríguez-López, AM; Sánchez-Ferrer, CF | 1 |
| d'Uscio, LV; Lüscher, TF; Moreau, P; Takase, H | 1 |
| de Jongste, JC; McKay, S; Saxena, PR; Sharma, HS | 1 |
| Lombardi, DM; Schwartz, SM; Siegal, J; Su, EJ | 1 |
| Dilley, RJ; Nataatmadja, MI | 1 |
| Parker, SB; Prewitt, RL; Wade, SS | 1 |
| Akers, M; Griendling, KK; Harrison, DG; Shah, A; Taylor, WR; Ushio-Fukai, M; Yin, Q; Zafari, AM | 1 |
| Hayashi, M; Ichihara, A; Kobori, H; Miyashita, Y; Saruta, T | 1 |
| Hannken, T; Schroeder, R; Stahl, RA; Wolf, G | 2 |
| Rao, GN | 1 |
| Fukuda, N; Hu, WY; Izumi, Y; Kanmatsuse, K; Kishioka, H; Kubo, A; Satoh, C; Soma, M; Watanabe, Y | 1 |
| Akers, M; Alexander, RW; Fujio, Y; Griendling, KK; Ushio-Fukai, M; Walsh, K; Yin, Q | 1 |
| Inoshita, S; Ito, H; Kuwahara, M; Marumo, F; Nakashima, O; Sasaki, S; Tamamori, M; Terada, Y | 1 |
| Ceiler, DL; De Mey, JG; Nelissen-Vrancken, HJ; Smits, JF | 1 |
| Cao, Z; Casley, D; Cooper, ME; Dean, R; Wu, L | 1 |
| Braun-Dullaeus, RC; Dzau, VJ; Mann, MJ; von der Leyen, HE; Ziegler, A | 1 |
| Danser, AH; Dekkers, DH; Lamers, JM; Saris, JJ; Saxena, PR; Schalekamp, MA; van Kesteren, CA | 1 |
| Ichihara, S; Inagami, T; Motley, ED; Numaguchi, K; Tanaka, S; Yamakawa, T; Yamakawa, Y | 1 |
| De Windt, LJ; Lim, HW; Molkentin, JD; Taigen, T | 1 |
| Hannken, T; Schroeder, R; Stahl, RAK; Wolf, G; Zahner, G | 1 |
| Bush, E; Dawson, TC; DeLeon, H; Kuziel, WA; Maeda, N; Taylor, WR; Wilcox, JN | 1 |
| Belabbas, H; Herizi, A; Jover, B; Mimran, A | 1 |
| Fujio, Y; Gualberto, A; Hassold, T; Hixon, ML; Kureishi, Y; Millie, E; Muro-Cacho, C; Obejero-Paz, C; Wagner, MW; Walsh, K | 1 |
| Hayashi, K; Iwamoto, K; Kizawa, Y; Kusama, T; Murakami, H; Saito, K; Sano, M | 1 |
| Burns, KD; Imig, JD; Kumar, D; Levine, DZ; Navar, LG; Wehbi, G; Zimpelmann, J | 1 |
| Booth, FW; Carlson, CJ; Davis, BS; Gordon, SE | 1 |
| Govindarajan, G; Lucchesi, PA; Rocic, P; Sabri, A | 1 |
| Brogelli, L; Donnini, S; Ledda, F; Parenti, A; Ziche, M | 1 |
| Chu, ZX; Gong, K; Miao, CY; Su, DF; Tao, X; Zhang, SH | 1 |
| Akers, M; Griendling, KK; Lassègue, B; Minieri, CA; Ushio-Fukai, M; Zafari, AM | 1 |
| Cayatte, AJ; Cohen, RA; Du, Y; Johns, DG; Quinn, MT; Wang, HD; Xu, S | 1 |
| Cernacek, P; Dao, HH; de Champlain, J; Larivière, R; Martens, FM; Moreau, P; Yamaguchi, N | 1 |
| Chen, L; Gu, ZL; Qin, TC; Yu, LX | 1 |
| Cui, R; Gao, C; Mei, X | 1 |
| Buttrick, PM; Geenen, DL; Goldspink, PH; Kimball, VA; McKinney, RD | 1 |
| Fatima, S; Lanting, L; Nadler, JL; Natarajan, R; Reddy, MA; Thimmalapura, PR | 1 |
| Liu, Y; Wang, M; Xu, D | 1 |
| Cohen, RA; Johns, DG; Wang, HD; Xu, S | 1 |
| Bernstein, HS; Dazin, P; Hlaing, M; Shen, X | 1 |
| Postnov, IuV | 1 |
| Batolo, D; Demetrio, G; Di Pentima, G; Martines, F | 1 |
| Berk, BC; Krug, LM | 1 |
| Düsing, R; Ko, Y; Nettekoven, W; Sachinidis, A; Vetter, H; Wieczorek, AJ | 1 |
| Higaki, J; Mikami, H; Morishita, R; Nagano, M; Nakamura, F; Ogihara, T; Tomita, N; Yu, H | 1 |
| Ganten, D; Paul, M | 1 |
| Folkow, B; Lever, AF; Lyall, F; Morton, JJ | 1 |
| Harris, RC | 1 |
| Dzau, VJ; Gibbons, GH; Pratt, RE | 1 |
| Casley, D; Johnston, CI; Katopothis, A; Mooser, V | 1 |
| Aceto, JF; Baker, KM | 1 |
| Higaki, J; Miyazaki, M; Morishita, R; Ogihara, T | 1 |
| Owens, GK | 1 |
| Chiu, AT; McCall, DE; Roscoe, WA; Timmermans, PB | 1 |
| Goldfarb, S; Neilson, EG; Wolf, G; Ziyadeh, FN | 1 |
| Meyer, TW; Miller, PL; Rennke, HG | 1 |
| Morgan, KG; Papageorgiou, P | 1 |
| Brown, WC; Griffin, SA; Korsgaard, N; Lever, AF; MacPherson, F; McGrath, JC; Mulvany, MJ; Wilson, VG | 1 |
| Dzau, VJ; Itoh, H; Pratt, RE | 1 |
| Berk, BC; Pouysségur, J; Rao, GN; Sardet, C | 1 |
| Berk, BC; Elder, E; Mitsuka, M | 1 |
| Beattie, EC; Griffin, SA; Lyall, F; MacPherson, F; Morton, JJ; Russo, D | 1 |
| Bobrowski, WF; Dominick, MA; Gough, AW; MacDonald, JR; Metz, AL | 1 |
| Berk, BC; Gordon, HM; Tsuda, T; Vekshtein, V | 1 |
| Fernandes, A | 1 |
| Geisterfer, AA; Owens, GK | 1 |
| Klin, M; Kuczera, M | 1 |
| Lever, AF; Lyall, F; Morton, JJ | 1 |
| Geisterfer, AA; Owens, GK; Peach, MJ | 1 |
| Mazzocchi, G; Nussdorfer, GG; Rebuffat, P; Robba, C | 2 |
| Belloni, AS; Malendowicz, LK; Mazzocchi, G; Nussdorfer, GG; Rebuffat, P | 1 |
| Emoto, R; Fukuzaki, H; Kubo, M; Kurozumi, H; Maehashi, N; Masuda, J; Miki, T; Nakanishi, O; Takarada, A; Yokota, Y | 1 |
| Pasternack, A | 1 |
| Imai, M; Murata, H; Ohbe, Y; Sokabe, H; Takita, S; Yabuta, K | 1 |
| Geelhoed, GW; Kelsch, RC; Oliver, WJ; Vander, AJ | 1 |
| Okano, M | 1 |
| Endo, J; Kono, T; Tanaka, S; Yamashiki, Y; Yoshino, K | 1 |
| Bloodworth, JM; Lobeck, CC; Mangos, JA; Trygstad, CW | 1 |
| Goodman, AD; Hartroft, PM; Vagnucci, AH | 1 |
| Bartter, FC | 1 |
| Bailey, JD; Balis, JU; Hartroft, P; Lynch, MJ; Sutherland, LE | 1 |
| Brown, JJ; Cost, WS; Desmit, EM; Fraser, R; Lever, AF; Robertson, JI | 1 |
| Arant, BS; Brackett, NC; Still, WJ; Young, RB | 1 |
| Heintz, R; Saleh, M | 1 |
| Aso, Y; Kawabe, K; Nakauchi, K; Takayasu, H | 1 |
| Pulver, W; Schmid, HJ | 1 |
| White, MG | 1 |
| Burmeister, H; Ruiz-Torres, A | 1 |
| Kuhlmann, U; Schweikert, HU; Siegenthaler, W; Stadelmann, O; Stiel, D; Trübestein, GK; Werning, C | 1 |
| Broyer, M; Godard, C; Royer, P; Vallotton, MB | 1 |
| Benderli, A; Better, OS; Chaimovitz, C; Levi, J; Oslander, L | 1 |
| Gantt, C; Grossman, A; Ramanathan, K | 1 |
| Gabrilove, JL; Krakoff, LR; Modlinger, RS; Nicolis, GL | 1 |
| Erkelens, DW; Statius van Eps, LW | 1 |
26 review(s) available for angiotensin ii and Hypertrophy
| Article | Year |
|---|---|
[Renal adaptation after experimental nephrectomy in animals: a review].
Topics: Angiotensin II; Animals; Disease Models, Animal; Glomerular Filtration Rate; Hypertrophy; Insulin-Like Growth Factor I; Kidney; Kidney Glomerulus; Nephrectomy; Recovery of Function; Transforming Growth Factor beta1; Vasoconstrictor Agents | 2013 |
Novel mechanisms of protein synthesis in diabetic nephropathy--role of mRNA translation.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Diabetic Nephropathies; Eukaryotic Initiation Factors; Extracellular Matrix; Humans; Hypertrophy; Kidney; MicroRNAs; Models, Biological; Peptide Chain Elongation, Translational; Protein Biosynthesis; RNA, Messenger; Signal Transduction | 2008 |
A transgenic mouse model for studying the role of the parathyroid hormone-related protein system in renal injury.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertrophy; Kidney Diseases; Mice; Mice, Transgenic; Parathyroid Hormone-Related Protein; Proteinuria | 2011 |
Structural changes in the renal vasculature in the spontaneously hypertensive rat: no effect of angiotensin II blockade.
Topics: Angiotensin II; Animals; Humans; Hypertension, Renovascular; Hypertrophy; Kidney Glomerulus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery | 1996 |
Vascular actions of aldosterone.
Topics: Adipocytes; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Vessels; Cardiovascular Diseases; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Hypertrophy; Metabolic Syndrome; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Muscle, Smooth, Vascular; Oxidative Stress; Receptor, Endothelin A; Receptors, Mineralocorticoid; Renin-Angiotensin System; Signal Transduction; Sodium; Vasculitis; Vasoconstriction | 2013 |
Angiotensin II and cell cycle regulation.
Topics: Angiotensin II; Animals; Apoptosis; Blood Vessels; Cardiovascular Diseases; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Size; Endothelins; G1 Phase; Heart; Humans; Hypertrophy; Kidney; Kidney Diseases; Myocardium | 2004 |
Proteinuria and its consequences in renal disease.
Topics: Angiotensin II; Chronic Disease; Disease Progression; Fabry Disease; Humans; Hyperlipidemias; Hypertension, Renal; Hypertrophy; Kidney Diseases; Kidney Glomerulus; Proteinuria | 2003 |
[Renin-angiotensin system and vascular remodelling].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Arteriosclerosis; Blood Pressure; Blood Vessels; Fibrosis; Humans; Hypertension, Renovascular; Hypertrophy; Inflammation; Models, Biological; NADPH Oxidases; Reactive Oxygen Species; Receptors, Angiotensin; Renin-Angiotensin System; Transforming Growth Factor beta | 2004 |
Vascular tone control in humans: insights from studies in Bartter's/Gitelman's syndromes.
Topics: Angiotensin II; Bartter Syndrome; Blood Pressure; Blood Vessels; Calcium; Cardiovascular System; Endothelium, Vascular; GTP-Binding Proteins; Humans; Hypertension; Hypertrophy; Juxtaglomerular Apparatus; Magnesium; Oxidative Stress; Signal Transduction; Syndrome | 2006 |
The pathogenesis of hypertension: the Baker concerto.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Hemodynamics; Humans; Hypertension; Hypertension, Renovascular; Hypertrophy; Sympathetic Nervous System | 1984 |
Internephron heterogeneity of growth factors and sclerosis.
Topics: Angiotensin II; Animals; Glomerulosclerosis, Focal Segmental; Growth Substances; Humans; Hypertrophy; Kidney Diseases; Kidney Glomerulus; Nephrectomy; Nephrons; Platelet-Derived Growth Factor; Proteinuria; Puromycin Aminonucleoside; Rats | 1994 |
Regulating factors of renal tubular hypertrophy.
Topics: Angiotensin II; Humans; Hypertrophy; Kidney Diseases; Kidney Tubules | 1993 |
Angiotensin II as a hypertrophogenic cytokine for proximal tubular cells.
Topics: Angiotensin II; Animals; Cytokines; Gene Expression; Growth Substances; Humans; Hypertrophy; In Vitro Techniques; Kidney Tubules, Proximal; Renin-Angiotensin System | 1993 |
Angiotensin II signal transduction and the mitogen-activated protein kinase pathway.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Humans; Hypertrophy; Muscle, Smooth, Vascular; Signal Transduction | 1995 |
Impaired proteolytic activity as a potential cause of progressive renal disease.
Topics: Acidosis; Ammonia; Angiotensin II; Animals; Diabetes Mellitus, Experimental; Dietary Proteins; Endopeptidases; Glomerulonephritis; Humans; Hypertrophy; Inflammation; Insulin-Like Growth Factor I; Kidney; Kidney Diseases; Proteins; Transforming Growth Factor beta | 1996 |
The role of angiotensin II and its receptors in regulation of adipose tissue metabolism and cellularity.
Topics: Adipose Tissue; Angiotensin II; Animals; Dietary Fats; Humans; Hypertrophy; Insulin Resistance; Mice; Obesity; Rats; Receptors, Angiotensin; Renin-Angiotensin System | 1995 |
The renin-angiotensin system and vascular hypertrophy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hyperplasia; Hypertrophy; Muscle, Smooth, Vascular; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 1996 |
Regulation of the gene-encoding angiotensin II receptor in vascular tissue.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arteries; Blood Pressure; Down-Regulation; Feedback; Humans; Hypertrophy; Macaca mulatta; Male; Rats; Rats, Wistar; Receptors, Angiotensin; RNA, Messenger; Sodium, Dietary | 1996 |
Renal tubular hypertrophy induced by angiotensin II.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cells, Cultured; Disease Models, Animal; Disease Progression; Hypertrophy; Kidney Diseases; Kidney Tubules; Rats; Renin-Angiotensin System | 1997 |
Vascular hypertrophy in hypertension: role of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Cell Division; Humans; Hypertension; Hypertrophy; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 1998 |
[Kidney in chronic arterial hypertension: "resetting" and the role of the renal medulla in its development].
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Chronic Disease; Diuresis; Homeostasis; Humans; Hypertension; Hypertrophy; Kidney; Kidney Medulla; Kidney Tubules; Natriuresis; Nephrosclerosis; Renin; Vascular Resistance | 1979 |
The molecular basis of cardiovascular hypertrophy: the role of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Blood Vessels; Cardiomegaly; Cell Division; Cells, Cultured; Gene Expression; Growth Substances; Hypertension; Hypertrophy; Muscle, Smooth, Vascular; Proto-Oncogenes; Renin-Angiotensin System | 1992 |
Angiotensin II, vascular structure and blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Cardiomegaly; Growth Substances; Hypertension; Hypertrophy; Models, Cardiovascular; Rats | 1992 |
Role of contractile agonists in growth regulation of vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Humans; Hypertension; Hypertrophy; Mitogens; Muscle Development; Muscle Proteins; Muscle, Smooth, Vascular; Vasoconstrictor Agents | 1991 |
[Physiopathology of arterial hypertension. Significance of the renin-angiotensin-aldosterone system and structural changes].
Topics: Angiotensin II; Cardiomegaly; Coronary Disease; Humans; Hypertension; Hypertrophy; Renin-Angiotensin System | 1989 |
["Hypertensive vascular changes" with and without hypertension].
Topics: Angiotensin II; Blood Vessels; Chronic Disease; Diarrhea; Female; Humans; Hyalin; Hyperaldosteronism; Hyperplasia; Hypertension; Hypertension, Malignant; Hypertrophy; Male; Necrosis; Nephrotic Syndrome; Renin; Vomiting | 1969 |
355 other study(ies) available for angiotensin ii and Hypertrophy
| Article | Year |
|---|---|
Exosomal MiR-29a in Cardiomyocytes Induced by Angiotensin II Regulates Cardiac Microvascular Endothelial Cell Proliferation, Migration and Angiogenesis by Targeting VEGFA.
Topics: Angiotensin II; Cell Proliferation; Culture Media, Conditioned; Exosomes; Humans; Hypertrophy; MicroRNAs; Myocytes, Cardiac; Neovascularization, Pathologic; Signal Transduction; Vascular Endothelial Growth Factor A | 2022 |
Sulfasalazine exacerbates angiotensin II-induced cardiac remodelling by activating Akt signal pathway.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibrosis; Hypertrophy; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Signal Transduction; Sulfasalazine; Ventricular Remodeling | 2022 |
lncRNA NBR2 attenuates angiotensin II-induced myocardial hypertrophy through repressing ER stress via activating LKB1/AMPK/Sirt1 pathway.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Humans; Hypertrophy; Myocytes, Cardiac; RNA, Long Noncoding; Signal Transduction; Sirtuin 1; Stroke Volume; Ventricular Function, Left | 2022 |
Rhein attenuates angiotensin II-induced cardiac remodeling by modulating AMPK-FGF23 signaling.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Anthraquinones; Fibroblast Growth Factor-23; Fibrosis; Heart Failure; Hypertrophy; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Ventricular Remodeling | 2022 |
Secreted frizzled-related protein 3 alleviated cardiac remodeling induced by angiotensin II via inhibiting oxidative stress and apoptosis in mice.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Fibrosis; Hypertrophy; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Rats; Ventricular Remodeling | 2022 |
PON2 ameliorates Ang II-induced cardiomyocyte injury by targeting the CANX/NOX4 signaling pathway.
Topics: Angiotensin II; Aryldialkylphosphatase; Calnexin; Humans; Hypertrophy; Myocytes, Cardiac; NADPH Oxidase 4; Signal Transduction | 2023 |
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Topics: Aloe; Angiotensin II; Animals; Cardiomyopathies; Emodin; Fibrosis; Hypertrophy; Mice; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Rats; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta1; Ventricular Remodeling | 2023 |
Vascular smooth muscle cells specific deletion of angiopoietin-like protein 8 prevents angiotensin II-promoted hypertension and cardiovascular hypertrophy.
Topics: Angiopoietin-Like Protein 8; Angiotensin II; Animals; Hypertension; Hypertrophy; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR | 2023 |
The POU4F2/Brn-3b transcription factor is required for the hypertrophic response to angiotensin II in the heart.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Calcineurin; Cardiovascular Diseases; Cyclin D1; Gene Expression Regulation; Glucose Transporter Type 4; Humans; Hypertrophy; Mice; Mice, Knockout; Myocardium; Myocytes, Cardiac; Primary Cell Culture; Rats; RNA, Small Interfering; Transcription Factor Brn-3B | 2019 |
Angiotensin-II Drives Human Satellite Cells Toward Hypertrophy and Myofibroblast Trans-Differentiation by Two Independent Pathways.
Topics: Angiotensin II; Calcium Signaling; Cell Survival; Cell Transdifferentiation; Humans; Hypertrophy; Molecular Imaging; Myoblasts; Myofibroblasts; Renin-Angiotensin System; Satellite Cells, Skeletal Muscle; Signal Transduction | 2019 |
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling.
Topics: Angiotensin II; Animals; Biomarkers; Blood Pressure; Cardiomegaly; Complement C3; Fibrosis; Hypertrophy; Interleukin-6; Lipopolysaccharide Receptors; Mice; Myocardium; Myocytes, Cardiac; Organ Size; RNA, Messenger; Systole; Toll-Like Receptors; Ventricular Remodeling | 2020 |
Effect of SKF‑96365 on cardiomyocyte hypertrophy induced by angiotensin II.
Topics: Actinin; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Cell Line; Cell Membrane; Cell Shape; Fluorescence; Gene Expression Regulation; Hypertrophy; Imidazoles; Myocytes, Cardiac; Rats; TRPC Cation Channels | 2020 |
TBC1D25 Regulates Cardiac Remodeling Through TAK1 Signaling Pathway.
Topics: Angiotensin II; Animals; Aorta; Cardiomegaly; Echocardiography; Gene Expression Regulation; GTPase-Activating Proteins; Heart Failure; Hypertrophy; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Knockout; Myocytes, Cardiac; Phosphorylation; Protein Domains; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventricular Remodeling | 2020 |
Novel Therapeutic Effects of Pterosin B on Ang II-Induced Cardiomyocyte Hypertrophy.
Topics: Angiotensin II; Animals; Cell Line; Cell Survival; Cytosol; Heart; HMGB1 Protein; Hypertrophy; Indans; Myocytes, Cardiac; NF-kappa B; Rats; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptor, Angiotensin, Type 1; Signal Transduction | 2020 |
Deficit of glucocorticoid-induced leucine zipper amplifies angiotensin-induced cardiomyocyte hypertrophy and diastolic dysfunction.
Topics: Angiotensin II; Animals; Blood Pressure; Capillaries; Cell Death; Diastole; Extracellular Matrix; Fibrosis; Hypertrophy; Hypertrophy, Left Ventricular; Inflammation; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Transcription Factors | 2021 |
Angiotensin II-induced histone deacetylase 5 phosphorylation, nuclear export, and Egr-1 expression are mediated by Akt pathway in A10 vascular smooth muscle cells.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Animals; Cell Line; Early Growth Response Protein 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Hypertrophy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2021 |
Developmental and lifelong dioxin exposure induces measurable changes in cardiac structure and function in adulthood.
Topics: Angiotensin II; Animals; Basic Helix-Loop-Helix Transcription Factors; Dioxins; Disease Models, Animal; Embryonic Development; Environmental Pollutants; Female; Heart; Heart Defects, Congenital; Humans; Hypertrophy; Male; Mice; Physical Conditioning, Animal; Pilot Projects; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Renin-Angiotensin System; Sex Characteristics | 2021 |
Rutin Modulates MAPK Pathway Differently from Quercetin in Angiotensin II-Induced H9c2 Cardiomyocyte Hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Cells, Cultured; Gene Expression Regulation, Enzymologic; Hypertrophy; Mitogen-Activated Protein Kinases; Myoblasts, Cardiac; NADPH Oxidases; Nitric Oxide; Phosphorylation; Quercetin; Rats; Reactive Oxygen Species; Rutin; Vasoconstrictor Agents | 2021 |
Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1/NF-κB pathway.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Cells, Cultured; Disease Models, Animal; Fibrosis; Ginsenosides; Humans; Hypertrophy; Immunomodulation; Inflammasomes; Myocardium; Myocytes, Cardiac; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Rats; Signal Transduction; Sirtuin 1 | 2021 |
Pressure-overload-induced angiotensin-mediated early remodeling in mouse heart.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Disease Models, Animal; Heart Diseases; Hypertrophy; Membrane Potentials; Mice, Inbred C57BL; Myocytes, Cardiac; Patch-Clamp Techniques; Pressure; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Saralasin; Stress, Physiological | 2017 |
STAT3 balances myocyte hypertrophy vis-à-vis autophagy in response to Angiotensin II by modulating the AMPKα/mTOR axis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Angiotensin II; Animals; Autophagy; Disease Models, Animal; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Hypertrophy; Myocytes, Cardiac; Pyridines; Rats; Signal Transduction; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Tyrphostins | 2017 |
Resveratrol prevents angiotensin II-induced hypertrophy of vascular smooth muscle cells through the transactivation of growth factor receptors.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Line; CSK Tyrosine-Protein Kinase; Enzyme Activation; Hypertrophy; Male; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Growth Factor; Resveratrol; Signal Transduction; src-Family Kinases; Stilbenes; Transcriptional Activation | 2017 |
VEGFB-VEGFR1 ameliorates Ang II-induced cardiomyocyte hypertrophy through Ca
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Cell Line; Cell Size; Cyclic GMP-Dependent Protein Kinase Type I; Gene Knockdown Techniques; Hypertrophy; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; Rats; Signal Transduction; Vascular Endothelial Growth Factor B; Vascular Endothelial Growth Factor Receptor-1 | 2018 |
Depletion of ubiA prenyltransferase domain containing 1 expression promotes angiotensin II‑induced hypertrophic response in AC16 human myocardial cells via modulating the expression levels of coenzyme Q10 and endothelial nitric oxide synthase.
Topics: Angiotensin II; Apoptosis; Atrial Natriuretic Factor; Caspase 3; Cell Line; Dimethylallyltranstransferase; Gene Expression; Humans; Hypertrophy; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type III; RNA Interference; RNA, Small Interfering; Ubiquinone | 2017 |
Interleukin-6 deficiency attenuates angiotensin II-induced cardiac pathogenesis with increased myocyte hypertrophy.
Topics: Angiotensin II; Animals; Cardiomyopathies; Cells, Cultured; Hypertrophy; Interleukin-6; Male; Mice; Mice, Knockout; Myocytes, Cardiac; STAT3 Transcription Factor | 2017 |
Deletion of the EGF receptor in vascular smooth muscle cells prevents chronic angiotensin II-induced arterial wall stiffening and media thickening.
Topics: Angiotensin II; Animals; ErbB Receptors; Hypertrophy; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Tunica Media; Vascular Remodeling; Vascular Stiffness | 2018 |
Angiotensin II upregulates cyclophilin A by enhancing ROS production in rat cardiomyocytes.
Topics: Angiotensin II; Animals; Cyclophilin A; Gene Expression Regulation; Humans; Hypertrophy; Myocardium; Myocytes, Cardiac; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction | 2018 |
The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Phosphoprotein Phosphatases; Transforming Growth Factor beta1; Vascular Remodeling | 2019 |
Ligand-activated PPARδ inhibits angiotensin II-stimulated hypertrophy of vascular smooth muscle cells by targeting ROS.
Topics: Angiotensin II; Animals; Cell Enlargement; Cells, Cultured; Hypertrophy; Ligands; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 1; PPAR delta; Protein Transport; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; RNA Interference; Thiazoles | 2019 |
Effect of muscarinic receptors agonist in the rat model of coronary heart disease: A potential therapeutic target in cardiovascular diseases.
Topics: Acetylcholine; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Electrocardiography; Hemodynamics; Hypertrophy; Male; Muscarinic Agonists; Rats; Receptor, Muscarinic M3; Ventricular Function, Left; Ventricular Myosins | 2018 |
Epigenetic modulation of tenascin C in the heart: implications on myocardial ischemia, hypertrophy and metabolism.
Topics: Angiotensin II; Animals; Cardiomegaly; Coronary Artery Disease; DNA Methylation; Energy Metabolism; Epigenesis, Genetic; Extracellular Matrix; Extracellular Matrix Proteins; Fibrosis; Heart Diseases; Humans; Hypertrophy; Hypoxia; Male; Matrix Metalloproteinase 2; MicroRNAs; Myocardial Infarction; Myocardium; Nerve Tissue Proteins; Rats; Tenascin; Ventricular Remodeling | 2019 |
Luteolin improves myocardial cell glucolipid metabolism by inhibiting hypoxia inducible factor-1α expression in angiotensin II/hypoxia-induced hypertrophic H9c2 cells.
Topics: Angiotensin II; Animals; Cardiomegaly; Carnitine O-Palmitoyltransferase; Fatty Acids, Nonesterified; Glucose; Glucose Transporter Type 4; Hypertrophy; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Luteolin; Myocardium; Myocytes, Cardiac; Plant Extracts; PPAR alpha; Protein Kinases; Rats | 2019 |
Topics: Angiotensin II; Animals; Biomarkers; Cell Line; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Hypertrophy; Myocytes, Cardiac; Nelumbo; Oxidative Stress; Plant Extracts; Protein Kinase C; Rats; Reactive Oxygen Species; Signal Transduction | 2019 |
[Aconitine ameliorates cardiomyocyte hypertrophy induced by angiotensin Ⅱ].
Topics: Aconitine; Actins; Angiotensin II; Atrial Natriuretic Factor; Cardiac Myosins; Cardiomegaly; Cells, Cultured; Humans; Hypertrophy; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain | 2019 |
Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.
Topics: Active Transport, Cell Nucleus; Adenoviridae; Angiotensin II; Animals; Calmodulin; Cell Membrane; Cell Nucleus; G-Protein-Coupled Receptor Kinase 5; Gene Expression Regulation, Enzymologic; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertrophy; Ligands; Male; Mice; Mice, Transgenic; Myocardium; Phenylephrine; Protein Binding; Protein Structure, Tertiary; Rabbits; Rats | 2013 |
A repressor protein, Mnt, is a novel negative regulator of vascular smooth muscle cell hypertrophy by angiotensin II and neointimal hyperplasia by arterial injury.
Topics: Adenoviridae; Angioplasty, Balloon; Angiotensin II; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carotid Artery Injuries; Green Fluorescent Proteins; Hyperplasia; Hypertrophy; Male; Muscle, Smooth, Vascular; Neointima; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Repressor Proteins; Signal Transduction; Transcription, Genetic | 2013 |
Boerhaavia diffusa L. attenuates angiotensin II-induced hypertrophy in H9c2 cardiac myoblast cells via modulating oxidative stress and down-regulating NF-κβ and transforming growth factor β1.
Topics: Angiotensin II; Animals; Antioxidants; Biomarkers; Cardiovascular Agents; Cell Line; Down-Regulation; Glutathione; Hypertrophy; Lipid Peroxidation; Myoblasts, Cardiac; Myocardium; NF-kappa B; Nyctaginaceae; Oxidative Stress; Plant Extracts; Protein Carbonylation; Rats; Reactive Oxygen Species; Transforming Growth Factor beta1 | 2013 |
[The functional changes in L-type Ca2+ channel of hypertrophied cardiomyocytes in neonatal rats induced by angiotensin II].
Topics: Angiotensin II; Animals; Calcium; Calcium Channels, L-Type; Female; Hypertrophy; Male; Membrane Potentials; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley | 2013 |
Tetramethylpyrazine inhibits angiotensin II-induced cardiomyocyte hypertrophy and tumor necrosis factor-α secretion through an NF-κB-dependent mechanism.
Topics: Angiotensin II; Animals; Cell Enlargement; Cells, Cultured; Enzyme Activation; Gene Expression Regulation; Hypertrophy; Myocytes, Cardiac; NF-kappa B; Protein Biosynthesis; Protein Transport; Pyrazines; Rats; Signal Transduction; Tumor Necrosis Factor-alpha | 2013 |
Kamolonol suppresses angiotensin II-induced stress fiber formation and cellular hypertrophy through inhibition of Rho-associated kinase 2 activity.
Topics: Angiotensin II; Animals; Cell Line; Coumarins; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Hypertrophy; Inhibitory Concentration 50; Phosphorylation; Rats; rho-Associated Kinases; Sesquiterpenes; Stress Fibers | 2013 |
Intrinsic-mediated caspase activation is essential for cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Bronchodilator Agents; Cardiomegaly; Caspase 3; Caspase 9; Cells, Cultured; Cysteine Proteinase Inhibitors; Endothelin-1; Enzyme Activation; Fluorescent Antibody Technique; Hypertrophy; In Vitro Techniques; Isoproterenol; Membrane Potential, Mitochondrial; Myocardium; Myocytes, Cardiac; Oligopeptides; Phenylephrine; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstrictor Agents | 2013 |
Role of IκB kinase-β in the growth-promoting effects of angiotensin II in vitro and in vivo.
Topics: Angiotensin II; Animals; Carrier Proteins; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Hypertrophy; I-kappa B Kinase; Inflammation Mediators; Infusions, Subcutaneous; Intracellular Signaling Peptides and Proteins; Male; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; RNA Interference; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Transfection; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins | 2013 |
Activation of angiotensin II type 1 receptor-associated protein exerts an inhibitory effect on vascular hypertrophy and oxidative stress in angiotensin II-mediated hypertension.
Topics: Adaptor Proteins, Signal Transducing; Aldehydes; Angiotensin II; Animals; Aorta; Cells, Cultured; Cytochrome b Group; Disease Models, Animal; Hypertension; Hypertrophy; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection | 2013 |
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
Topics: Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Heart Ventricles; Humans; Hypertrophy; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Neurotransmitter Agents; Nitric Oxide Synthase; Receptors, Adrenergic, beta-3; Signal Transduction; Ventricular Remodeling | 2014 |
GSTpi protects against angiotensin II-induced proliferation and migration of vascular smooth muscle cells by preventing signal transducer and activator of transcription 3 activation.
Topics: Angiotensin II; Animals; Cell Movement; Cell Nucleus; Cell Proliferation; Cytoprotection; Gene Knockdown Techniques; Glutathione S-Transferase pi; Hypertrophy; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Protein Binding; Protein Transport; Rats; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor | 2014 |
Endogenous endothelin 1 mediates angiotensin II-induced hypertrophy in electrically paced cardiac myocytes through EGFR transactivation, reactive oxygen species and NHE-1.
Topics: Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Cats; Disease Models, Animal; Electric Stimulation; Endothelin-1; ErbB Receptors; Hypertrophy; Myocytes, Cardiac; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Signal Transduction; Sodium-Hydrogen Exchangers; Transcriptional Activation | 2014 |
Nardosinone protects H9c2 cardiac cells from angiotensin II-induced hypertrophy.
Topics: Angiotensin II; Animals; Cardiotonic Agents; Cell Line; Cell Size; Hypertrophy; MAP Kinase Signaling System; Myoblasts, Cardiac; Phosphatidylinositol 3-Kinases; Polycyclic Sesquiterpenes; Proto-Oncogene Proteins c-akt; Rats; RNA, Messenger; Sesquiterpenes; TOR Serine-Threonine Kinases | 2013 |
EPC-derived microvesicles protect cardiomyocytes from Ang II-induced hypertrophy and apoptosis.
Topics: Angiotensin II; Animals; Apoptosis; Cell Line; Cell Survival; Cell-Derived Microparticles; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Hypertrophy; Mice; Myocytes, Cardiac; Nitric Oxide Synthase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; RNA; Signal Transduction; Stem Cells | 2014 |
Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Hypertrophy; I-kappa B Kinase; In Vitro Techniques; Interferon Regulatory Factor-7; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; NF-kappa B; Signal Transduction | 2014 |
Aliskiren limits abdominal aortic aneurysm, ventricular hypertrophy and atherosclerosis in an apolipoprotein-E-deficient mouse model.
Topics: Amides; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Fumarates; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; Mice, Knockout | 2014 |
Effects of a domain-selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Cardiomegaly; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Hypertension; Hypertrophy; Kidney; Lisinopril; Mice; Mice, Transgenic | 2014 |
An ongoing role of α-calcitonin gene-related peptide as part of a protective network against hypertension, vascular hypertrophy, and oxidative stress.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Endothelins; Hypertension; Hypertrophy; Mesentery; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Signal Transduction; Vasodilation | 2014 |
Enhanced expression of Gqα and PLC-β1 proteins contributes to vascular smooth muscle cell hypertrophy in SHR: role of endogenous angiotensin II and endothelin-1.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Phospholipase C beta; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; RNA Interference; Signal Transduction; Transcription Factor AP-1; Transfection; Up-Regulation | 2014 |
Overexpression of PEP-19 suppresses angiotensin II-induced cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Calcineurin; Calcium; Calcium Signaling; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Calmodulin-Binding Proteins; Cardiomegaly; Cells, Cultured; Gene Expression; Hypertrophy; Male; Myocytes, Cardiac; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Rats, Sprague-Dawley; Sarcoplasmic Reticulum | 2014 |
Identification of regulatory elements directing miR-23a-miR-27a-miR-24-2 transcriptional regulation in response to muscle hypertrophic stimuli.
Topics: 3T3 Cells; Angiotensin II; Animals; Cardiomegaly; Gene Expression Regulation; Genes, Regulator; Hypertrophy; Mice; MicroRNAs; Muscle, Skeletal; Myocytes, Cardiac; Norepinephrine; Promoter Regions, Genetic; Transcription, Genetic | 2014 |
Unexpected anti-hypertrophic responses to low-level stimulation of protease-activated receptors in adult rat cardiomyocytes.
Topics: Angiotensin II; Animals; Cell Enlargement; Dose-Response Relationship, Drug; Humans; Hypertrophy; Myocytes, Cardiac; Rats; Receptor, PAR-1; Receptor, PAR-2; Swine; Thrombin | 2014 |
An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Bradykinin B1 Receptor Antagonists; Cells, Cultured; Drug Synergism; Hypertension; Hypertrophy; Kallikrein-Kinin System; Losartan; Male; Myocytes, Smooth Muscle; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Bradykinin B1; Renin-Angiotensin System; Superoxides | 2014 |
Impaired myocardial development resulting in neonatal cardiac hypoplasia alters postnatal growth and stress response in the heart.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Embryonic Development; Female; Fetal Development; Heart; Hypertrophy; Lyases; Mice; Mice, Knockout; Models, Animal; Myocytes, Cardiac; Organ Size; STAT3 Transcription Factor; Stress, Physiological | 2015 |
The role of mAKAPβ in the process of cardiomyocyte hypertrophy induced by angiotensin II.
Topics: A Kinase Anchor Proteins; Angiotensin II; Animals; Biomarkers; Cardiomegaly; Disease Models, Animal; Gene Expression; Hypertrophy; Male; Mitogen-Activated Protein Kinase 1; Myocytes, Cardiac; Rats; RNA Interference; RNA, Small Interfering | 2015 |
Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Disease Models, Animal; Endoplasmic Reticulum Stress; Endothelium, Vascular; ErbB Receptors; Erlotinib Hydrochloride; Hypertension; Hypertrophy; Mice; Muscle, Smooth, Vascular; Phenylbutyrates; Quinazolines; Random Allocation; Role; Sensitivity and Specificity; Signal Transduction; Vascular Remodeling | 2015 |
Medicinal effect and its JP2/RyR2-based mechanism of Smilax glabra flavonoids on angiotensin II-induced hypertrophy model of cardiomyocytes.
Topics: Angiotensin II; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Flavonoids; Hypertrophy; Membrane Proteins; Myocytes, Cardiac; Phytotherapy; Plant Roots; Primary Cell Culture; Rats; Rhizome; Ryanodine Receptor Calcium Release Channel; Smilax | 2015 |
A different role of angiotensin II type 1a receptor in the development and hypertrophy of plantaris muscle in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Gene Expression; Hypertrophy; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Muscle, Skeletal; Receptor, Angiotensin, Type 1; RNA, Messenger; SKP Cullin F-Box Protein Ligases | 2016 |
Tumor necrosis factor receptor-associated factor 3 is a positive regulator of pathological cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Female; Humans; Hypertrophy; Male; Mice; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; Phenylephrine; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TNF Receptor-Associated Factor 3; Up-Regulation | 2015 |
[Angiotensin II induced myocardial hypertrophy in neonatal rats could be attenuated by activated κ-opioid receptor via modulating the calcineurin signal pathways].
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Angiotensin II; Aniline Compounds; Animals; Animals, Newborn; Calcineurin; Cells, Cultured; Hypertrophy; Myocardium; Myocytes, Cardiac; Rats; Receptors, Opioid, kappa; Signal Transduction; Xanthenes | 2015 |
A Food-Derived Flavonoid Luteolin Protects against Angiotensin II-Induced Cardiac Remodeling.
Topics: Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Connective Tissue Growth Factor; Diet; Fibroblasts; Fibrosis; Flavonoids; Food; Heart; Hydrogen Peroxide; Hypertrophy; Luteolin; Male; Myocardium; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Transforming Growth Factor beta1; Ventricular Remodeling | 2015 |
Roles of Caveolin-1 in Angiotensin II-Induced Hypertrophy and Inward Remodeling of Cerebral Pial Arterioles.
Topics: Angiotensin II; Animals; Arterioles; Caveolin 1; Disease Models, Animal; Gene Expression Regulation; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; RNA; Vascular Remodeling | 2016 |
Role of α1D -adrenoceptors in vascular wall hypertrophy during angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 2015 |
[Effect of resveratrol on aniogtensin II induced cardiomyocytes hypertrophy and FoxO1/MnSOD signaling pathway].
Topics: Angiotensin II; Animals; Animals, Newborn; Forkhead Transcription Factors; Hypertrophy; Myocytes, Cardiac; Nerve Tissue Proteins; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase | 2015 |
Alpinate Oxyphyllae Fructus Inhibits IGFII-Related Signaling Pathway to Attenuate Ang II-Induced Pathological Hypertrophy in H9c2 Cardiomyoblasts.
Topics: Alpinia; Angiotensin II; Animals; Cell Line; Humans; Hypertrophy; Insulin-Like Growth Factor II; Myocytes, Cardiac; Plant Extracts; Rats; Signal Transduction | 2016 |
Velvet antler peptide prevents pressure overload-induced cardiac fibrosis via transforming growth factor (TGF)-β1 pathway inhibition.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Antlers; Aorta; Blood Pressure; Cell Proliferation; Connective Tissue Growth Factor; Fibroblasts; Fibrosis; Gene Expression Regulation; Hypertrophy; Myocardium; Oxidative Stress; Peptides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1; Vasoconstriction | 2016 |
Histone deacetylase and GATA-binding factor 6 regulate arterial remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cells, Cultured; DNA; GATA6 Transcription Factor; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Hypertension; Hypertrophy; Kidney; Male; Mice; Muscle, Smooth, Vascular; Phosphorylation; Pyrroles; Repressor Proteins; Vascular Remodeling | 2016 |
Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; ATPases Associated with Diverse Cellular Activities; DNA Helicases; Femoral Artery; Humans; Hypertrophy; Lipopolysaccharides; Mice; Mice, Knockout; Muscle, Smooth, Vascular; NADPH Oxidase 1; Oxidative Stress; Phosphoproteins; Proteins; Reactive Oxygen Species; Sodium-Hydrogen Exchangers; Superoxides; Vasoconstriction | 2016 |
Involvement of vascular peroxidase 1 in angiotensin II-induced hypertrophy of H9c2 cells.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Cell Line; Disease Models, Animal; Endothelium, Vascular; Gene Knockdown Techniques; Hemeproteins; Hydrogen Peroxide; Hypertension; Hypertrophy; Hypochlorous Acid; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NADPH Oxidase 2; Onium Compounds; Oxidative Stress; Peroxidases; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2017 |
Cellular Repressor of E1A-Stimulated Genes Is a Critical Determinant of Vascular Remodeling in Response to Angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Protein c-ets-1; Rats, Inbred Dahl; Recombinant Proteins; Repressor Proteins; RNA Interference; Signal Transduction; Sodium Chloride, Dietary; Time Factors; Transfection; Vascular Remodeling | 2017 |
Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Substitution; Angiotensin II; Animals; Cells, Cultured; Fibronectins; Fibrosis; Gene Expression Regulation; Glomerular Mesangium; Humans; Hypertrophy; Kidney Diseases; Mutation, Missense; NADPH Oxidase 4; NADPH Oxidases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Reactive Oxygen Species; RNA, Small Interfering; src-Family Kinases; Vasoconstrictor Agents | 2008 |
Effect of sodium tanshinone II A sulfonate on phosphorylation of extracellular signal-regulated kinase 1/2 in angiotensin II-induced hypertrophy of myocardial cells.
Topics: Angiotensin II; Animals; Hypertrophy; Leucine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Phenanthrenes; Phosphorylation; Protein Biosynthesis; Protein Transport; Rats; Rats, Wistar; Tritium | 2008 |
Metallothionein suppresses angiotensin II-induced nicotinamide adenine dinucleotide phosphate oxidase activation, nitrosative stress, apoptosis, and pathological remodeling in the diabetic heart.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomyopathies; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Fibrosis; Hypertrophy; Metallothionein; Mice; Mice, Transgenic; Myocardium; Myocytes, Cardiac; NADP; Oxidative Stress; Ventricular Remodeling | 2008 |
Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin II are prevented by AMP-activated protein kinase.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiotensin II; Animals; Catalytic Domain; Cells, Cultured; Gene Expression Regulation, Enzymologic; Glucose; Hypertrophy; Hypoglycemic Agents; Mice; Models, Biological; Myocytes, Cardiac; Phosphorylation; Rats; Ribonucleotides | 2008 |
Effect of sodium tanshinone II A sulfonate on cardiac myocyte hypertrophy and its underlying mechanism.
Topics: Angiotensin II; Animals; Animals, Newborn; Cell Survival; Gene Expression Regulation; Hypertrophy; Leucine; Myocytes, Cardiac; Phenanthrenes; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Tritium | 2008 |
Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Carboxypeptidases; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Renovascular; Hypertrophy; Indole Alkaloids; Kallikreins; Losartan; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2009 |
Functional characterization and transcriptome analysis of embryonic stem cell-derived contractile smooth muscle cells.
Topics: Actins; Angiotensin II; Animals; Calcium-Binding Proteins; Calponins; Cell Differentiation; Cells, Cultured; Desmin; Embryonic Stem Cells; Endothelins; Gene Expression Profiling; Hypertrophy; KATP Channels; Mice; Mice, Transgenic; Microfilament Proteins; Muscle Contraction; Muscle Proteins; Myocytes, Smooth Muscle; Myosin Heavy Chains; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated | 2009 |
Glomerular surface area is normalized in mice born with a nephron deficit: no role for AT1 receptors.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Heart Rate; Heterozygote; Hypertrophy; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Organ Size; Receptor, Angiotensin, Type 1; Tetrazoles | 2009 |
Dietary fish oil is antihypertrophic but does not enhance postischemic myocardial function in female mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Arrhythmias, Cardiac; Dietary Fats, Unsaturated; Disease Models, Animal; Estrogens; Female; Fish Oils; Genetic Predisposition to Disease; Hypertrophy; Mice; Mice, Transgenic; Myocardial Ischemia; Myocardium; Ovariectomy; Reperfusion Injury | 2009 |
PPARdelta activation inhibits angiotensin II induced cardiomyocyte hypertrophy by suppressing intracellular Ca2+ signaling pathway.
Topics: Angiotensin II; Animals; Calcium; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Hypertrophy; Myocytes, Cardiac; PPAR delta; Rats; Signal Transduction | 2009 |
Aldosterone blockade by Spironolactone improves the hypertensive vascular hypertrophy and remodeling in angiotensin II overproducing transgenic mice.
Topics: Aldosterone; Angiotensin II; Animals; Female; Hyperplasia; Hypertension; Hypertrophy; Male; Mice; Mice, Transgenic; Mineralocorticoid Receptor Antagonists; Osteopontin; Renin-Angiotensin System; Spironolactone; Tunica Intima | 2009 |
Hypertrophic response to angiotensin II is mediated by protein kinase D-extracellular signal-regulated kinase 5 pathway in human aortic smooth muscle cells.
Topics: Angiotensin II; Aorta; Gene Knockdown Techniques; Humans; Hypertrophy; Mitogen-Activated Protein Kinase 7; Myocytes, Smooth Muscle; Phosphorylation; Protein Kinase C; Protein Transport; Receptor, Angiotensin, Type 1; RNA, Small Interfering; Signal Transduction | 2009 |
Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Heart Diseases; Heart Ventricles; Hypertension; Hypertrophy; Inflammation; Macrophages; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta; Ventricular Remodeling | 2009 |
Angiotensin II induces cardiomyocyte hypertrophy probably through histone deacetylases.
Topics: Angiotensin II; Animals; Animals, Newborn; Cell Enlargement; Cell Size; Cells, Cultured; Gene Expression; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; Hypertrophy; Myocytes, Cardiac; Myosin Heavy Chains; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Valproic Acid | 2009 |
Inhibition of farnesylpyrophosphate synthase prevents angiotensin II-induced hypertrophic responses in rat neonatal cardiomyocytes: involvement of the RhoA/Rho kinase pathway.
Topics: Alendronate; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Dimethylallyltranstransferase; Hypertrophy; Myocytes, Cardiac; Prenylation; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2009 |
Cyclic GMP kinase and RhoA Ser188 phosphorylation integrate pro- and antifibrotic signals in blood vessels.
Topics: Angiotensin II; Animals; Blood Vessels; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Fibrosis; Gene Expression Regulation; Humans; Hypertrophy; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Mutant Proteins; Organ Specificity; Phosphorylation; Phosphoserine; Protein Biosynthesis; rho-Associated Kinases; rhoA GTP-Binding Protein; Serum Response Element; Signal Transduction; Transcription, Genetic | 2009 |
Expression and distribution of NADPH oxidase isoforms in human myometrium--role in angiotensin II-induced hypertrophy.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cell Line; Female; Gene Expression; Humans; Hypertrophy; Isoenzymes; Leucine; Losartan; Myometrium; NADPH Oxidases; Pregnancy; Protein Biosynthesis; Receptor, Angiotensin, Type 1; Tritium | 2010 |
Protection of angiotensin II-induced vascular hypertrophy in vascular smooth muscle-targeted receptor activity-modifying protein 2 transgenic mice.
Topics: Adrenomedullin; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Female; Hypertension; Hypertrophy; Hypotension; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Vasculitis | 2009 |
PGC-1 alpha serine 570 phosphorylation and GCN5-mediated acetylation by angiotensin II drive catalase down-regulation and vascular hypertrophy.
Topics: Acetylation; Angiotensin II; Animals; Aorta, Thoracic; Cardiovascular Diseases; Catalase; Cells, Cultured; Down-Regulation; Forkhead Transcription Factors; Hypertrophy; Luciferases; Male; Muscle, Smooth, Vascular; Nerve Tissue Proteins; p300-CBP Transcription Factors; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Serine; Transcription Factors; Transcriptional Activation | 2010 |
Calmodulin kinase II is required for angiotensin II-mediated vascular smooth muscle hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Benzylamines; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carrier Proteins; Cells, Cultured; Disease Models, Animal; Histone Deacetylases; Hypertrophy; MADS Domain Proteins; Male; MEF2 Transcription Factors; Muscle, Smooth, Vascular; Myogenic Regulatory Factors; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides | 2010 |
Protein kinase C epsilon-dependent extracellular signal-regulated kinase 5 phosphorylation and nuclear translocation involved in cardiomyocyte hypertrophy with angiotensin II stimulation.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Animals; Cell Enlargement; Hypertrophy; MEF2 Transcription Factors; Mitogen-Activated Protein Kinase 7; Myocytes, Cardiac; Myogenic Regulatory Factors; Phosphorylation; Protein Kinase C-epsilon; Rats | 2010 |
[Eukaryotic expression vector pcDNA3-HERG transfection inhibits angiotensin II induced neonatal rabbit ventricular myocyte hypertrophy in vitro].
Topics: Angiotensin II; Animals; Calcineurin; Cells, Cultured; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Heart Ventricles; Humans; Hypertrophy; Myocytes, Cardiac; Patch-Clamp Techniques; Plasmids; Rabbits; Transfection | 2009 |
Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Disease Models, Animal; Heart Diseases; Hyperthyroidism; Hypertrophy; Imidazoles; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Thyroxine | 2010 |
Parathyroid hormone-related protein induces hypertrophy in podocytes via TGF-beta(1) and p27(Kip1): implications for diabetic nephropathy.
Topics: Angiotensin II; Animals; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Nephropathies; Disease Models, Animal; Glucose; Hypertrophy; Mice; Parathyroid Hormone-Related Protein; Peptide Fragments; Podocytes; Signal Transduction; Transforming Growth Factor beta1 | 2010 |
Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Arthritis, Experimental; Biphenyl Compounds; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Hypertrophy; Irbesartan; Losartan; Male; Oxidative Stress; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Reduction Behavior; Tetrazoles; Vasoconstrictor Agents | 2010 |
Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity.
Topics: Angiotensin II; Animals; Blotting, Western; Gene Expression; Gene Expression Regulation; Hypertrophy; Insulin-Like Growth Factor I; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Cardiac; Oxidative Stress; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sirtuin 1; Transfection | 2009 |
Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters.
Topics: Angiotensin II; Animals; Blotting, Western; Chymases; Cricetinae; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hypertension, Pulmonary; Hypertrophy; Immunoassay; Immunohistochemistry; Male; Oligopeptides; Pulmonary Artery; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Smad Proteins; Smoking; Time Factors; Transforming Growth Factor beta1; Up-Regulation; Ventricular Function, Right; Ventricular Pressure | 2010 |
Angiotensin II and the ERK pathway mediate the induction of myocardin by hypoxia in cultured rat neonatal cardiomyocytes.
Topics: Angiotensin II; Animals; Cell Hypoxia; Cell Nucleus; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Heart Ventricles; Hypertrophy; Myocytes, Cardiac; Nuclear Proteins; Phosphorylation; Rats; Rats, Wistar; RNA, Messenger; Serum Response Factor; Signal Transduction; Trans-Activators; Transcription, Genetic | 2010 |
Attenuated cardiovascular hypertrophy and oxidant generation in response to angiotensin II infusion in glutaredoxin-1 knockout mice.
Topics: Actin Cytoskeleton; Angiotensin II; Animals; Aorta; Cardiovascular Diseases; Cell Line; Glutaredoxins; Hypertrophy; Infusion Pumps; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nitric Oxide Synthase Type II; Oncogene Protein v-akt; Oxidants; RNA, Small Interfering; Tyrosine | 2010 |
[Effects of Rhein on the hypertrophy of renal proximal tubular epithelial cells induced by high glucose and angiotensin II in rats].
Topics: Angiotensin II; Animals; Anthraquinones; Cells, Cultured; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial Cells; Glucose; Hypertrophy; Kidney Tubules, Proximal; Leucine; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Rheum | 2010 |
SIRT1 inhibits angiotensin II-induced vascular smooth muscle cell hypertrophy.
Topics: Angiotensin II; Animals; Cell Line; GATA6 Transcription Factor; Humans; Hypertrophy; Mice; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Rats; Sirtuin 1 | 2011 |
Caveolin-1 negatively regulates a metalloprotease-dependent epidermal growth factor receptor transactivation by angiotensin II.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; beta-Cyclodextrins; Calcium; Caveolin 1; Cell Movement; Cells, Cultured; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Filipin; Gene Transfer Techniques; Hypertrophy; Membrane Microdomains; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Transcriptional Activation; Ventricular Remodeling | 2011 |
Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Cell Line, Transformed; Cell Survival; Cells, Cultured; HeLa Cells; Humans; Hypertrophy; Myocytes, Cardiac; Peptide Fragments; Rabbits; Rats; Receptor, Angiotensin, Type 2; Signal Transduction | 2011 |
An extract from brown rice inhibits signal transduction of angiotensin II in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; ErbB Receptors; Hypertrophy; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oryza; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Signal Transduction | 2011 |
Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1-7) mas receptor expression associated with its PPAR-γ agonist action.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Benzoates; Collagen Type III; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Hypertrophy; Intracellular Signaling Peptides and Proteins; Kidney; Mice; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; PPAR gamma; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Superoxides; Telmisartan; Transforming Growth Factor beta1; Up-Regulation | 2011 |
[Effect of tetramethylpyrazine on JAK-STAT signal transduction in cardiomyocyte hypertrophy].
Topics: Angiotensin II; Animals; Cells, Cultured; Hypertrophy; Janus Kinases; Myocytes, Cardiac; Pyrazines; Rats; Rats, Wistar; Signal Transduction; STAT Transcription Factors | 2011 |
PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality.
Topics: Angiotensin II; Animals; Becaplermin; Cell Line; Cell Movement; Gene Expression Regulation; Hypertrophy; Ligands; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Receptors, G-Protein-Coupled; Receptors, Platelet-Derived Growth Factor; RGS Proteins; RNA Interference; Signal Transduction; Time Factors; Transfection; Vasoconstriction | 2011 |
Nilotinib attenuates renal injury and prolongs survival in chronic kidney disease.
Topics: Angiotensin II; Animals; Benzamides; Collagen; Fibroblasts; Hypertrophy; Imatinib Mesylate; Kidney; Kidney Failure, Chronic; Male; Mesangial Cells; Nephrectomy; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor beta; Treatment Outcome | 2011 |
Angiotensin II shifts insulin signaling into vascular remodeling from glucose metabolism in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Size; Cells, Cultured; Glucose; Hypertrophy; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2011 |
Angiotensin II type-1 receptor-JAK/STAT pathway mediates the induction of visfatin in angiotensin II-induced cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Hypertrophy; Janus Kinases; Myocytes, Cardiac; Natriuretic Peptide, Brain; Nicotinamide Phosphoribosyltransferase; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; STAT Transcription Factors | 2012 |
Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK.
Topics: Actins; Angiotensin II; Animals; Blotting, Western; Enzyme Inhibitors; Hypertrophy; Immunoprecipitation; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection | 2011 |
Gαq-protein carboxyl terminus imitation polypeptide GCIP-27 attenuates proliferation of vascular smooth muscle cells and vascular remodeling in spontaneously hypertensive rats.
Topics: 3T3 Cells; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Blood Pressure Determination; Calcium; Cardiotonic Agents; Cell Culture Techniques; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Hypertrophy; Losartan; Male; Mice; Molecular Targeted Therapy; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptides; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Tetrazolium Salts; Thiazoles; Type C Phospholipases; Vasoconstrictor Agents | 2011 |
Angiotensin IV protects against angiotensin II-induced cardiac injury via AT4 receptor.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Fibroblasts; Heart; Hypertrophy; Male; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reperfusion Injury; RNA, Small Interfering | 2011 |
Constitutive stimulation of vascular smooth muscle cells by angiotensin II derived from an adenovirus encoding a furin-cleavable fusion protein.
Topics: Adenoviridae; Angiotensin II; Animals; Carotid Artery, Common; Cells, Cultured; Early Growth Response Protein 1; Furin; Gene Expression; Genetic Vectors; Hypertrophy; Mice; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley | 2012 |
Cooperative interaction between reactive oxygen species and Ca2+ signals contributes to angiotensin II-induced hypertrophy in adult rat cardiomyocytes.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Down-Regulation; Hypertrophy; Male; Myocytes, Cardiac; NADPH Oxidases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Superoxides | 2012 |
iPLA2β overexpression in smooth muscle exacerbates angiotensin II-induced hypertension and vascular remodeling.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Blood Pressure; Cell Proliferation; Diastole; Group VI Phospholipases A2; Hypertension; Hypertrophy; Leucine; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Rats; Signal Transduction | 2012 |
Heart angiotensin II-induced cardiomyocyte hypertrophy suppresses coronary angiogenesis and progresses diabetic cardiomyopathy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apoptosis; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Hypertrophy; Hypertrophy, Left Ventricular; Imidazoles; Male; Myocytes, Cardiac; Neovascularization, Physiologic; Olmesartan Medoxomil; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Tetrazoles; Thrombospondin 1; Vascular Endothelial Growth Factor A; Ventricular Dysfunction, Left | 2012 |
Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.
Topics: Angiotensin II; Animals; Antioxidants; Apoptosis; Boranes; Carbon Dioxide; Carbonates; Catalase; Cells, Cultured; Cytoprotection; Disease Models, Animal; Endothelial Cells; Heme Oxygenase-1; Hemin; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypertension; Hypertrophy; Ischemia; Lung; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Physiologic; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Organometallic Compounds; Oxidative Stress; Polyethylene Glycols; RNA, Messenger; Time Factors; Transfection | 2012 |
KS370G, a synthetic caffeamide derivative, improves left ventricular hypertrophy and function in pressure-overload mice heart.
Topics: Actins; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Caffeic Acids; Cardiotonic Agents; Collagen; Constriction; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Ventricles; Hypertrophy; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred ICR; Myocytes, Cardiac; Phosphoproteins; Pressure; Proto-Oncogene Proteins c-akt; Time Factors | 2012 |
Role of NF-κB and p38 MAPK activation in mediating angiotensin II and endothelin-1-induced stimulation in leptin production and cardiomyocyte hypertrophy.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Animals; Cell Enlargement; Cell Nucleus; Cell Size; Cells, Cultured; Endothelin-1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hypertrophy; Leptin; Myocytes, Cardiac; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Rats; Rats, Sprague-Dawley | 2012 |
Phosphorylation of smooth muscle 22α facilitates angiotensin II-induced ROS production via activation of the PKCδ-P47phox axis through release of PKCδ and actin dynamics and is associated with hypertrophy and hyperplasia of vascular smooth muscle cells in
Topics: Actins; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Down-Regulation; Enzyme Activation; Green Fluorescent Proteins; Humans; Hyperplasia; Hypertrophy; Male; Microfilament Proteins; Microscopy, Confocal; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Phosphorylation; Protein Binding; Protein Kinase C-delta; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA Interference | 2012 |
Effect of hepatocyte growth factor and angiotensin II on rat cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Hepatocyte Growth Factor; Hypertrophy; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
[Effect of Leonurus stachydrine on myocardial cell hypertrophy].
Topics: Angiotensin II; Animals; Cells, Cultured; Hypertrophy; I-kappa B Kinase; Leonurus; Myocytes, Cardiac; NF-kappa B; Proline; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction | 2012 |
Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes.
Topics: Angiotensin II; Animals; Cells, Cultured; Endothelin-1; Hypertrophy; Leptin; Male; Myocytes, Cardiac; Pressure; Protein Isoforms; Rats; Rats, Wistar; Receptors, Leptin; RNA, Messenger; STAT3 Transcription Factor; Stress, Mechanical; Up-Regulation | 2012 |
MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy.
Topics: Angiotensin II; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Heart Defects, Congenital; Humans; Hypertrophy; MicroRNAs; Myocytes, Cardiac; Rats; Up-Regulation | 2013 |
Stretch-induced paracrine hypertrophic stimuli increase TGF-beta1 expression in cardiomyocytes.
Topics: Angiotensin II; Animals; Blotting, Northern; Cells, Cultured; Endothelin-1; Fibroblasts; Hypertrophy; Male; Muscle, Smooth; Myocardium; Paracrine Communication; Rats; Rats, Wistar; RNA; RNA, Messenger; Stress, Mechanical; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Cyr61 and CTGF are molecular markers of bladder wall remodeling after outlet obstruction.
Topics: Angiotensin II; Animals; Biomarkers; Connective Tissue Growth Factor; Cysteine-Rich Protein 61; Endothelin-1; Gene Expression; Growth Substances; Hypertrophy; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Male; Parathyroid Hormone-Related Protein; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Urinary Bladder; Urinary Bladder Neck Obstruction; Vasoconstrictor Agents | 2002 |
Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Drug Interactions; Enzyme Activation; Hypertrophy; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Ribosomal Protein S6 Kinases; Stilbenes | 2002 |
Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth.
Topics: Angiotensin II; Animals; Blotting, Western; Calcineurin; Cell Division; Cell Nucleus; DNA-Binding Proteins; Female; Gene Targeting; Hypertrophy; Male; Mice; Models, Genetic; Mutagenesis; Mutagenesis, Site-Directed; Myocardium; NFATC Transcription Factors; Protein Isoforms; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factors; Transgenes | 2002 |
Interaction of MAPK and 12-lipoxygenase pathways in growth and matrix protein expression in mesangial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Angiotensin II; Animals; Arachidonate 12-Lipoxygenase; Cell Division; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Diabetic Nephropathies; Extracellular Matrix Proteins; Fibronectins; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Hypertrophy; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; RNA, Messenger; Vasoconstrictor Agents | 2002 |
[Effects of praeruptorin C on cell hypertrophy, intracellular [Ca2+]i, nitric oxide and signal transduction in isolated hypertrophied rat smooth muscle cells induced by angiotensin II].
Topics: Angiotensin II; Animals; Aorta; Calcium; Calcium Channel Blockers; Cells, Cultured; Coumarins; Female; Hypertrophy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction | 2002 |
Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes.
Topics: Angiotensin II; Animals; Bromodeoxyuridine; Cell Culture Techniques; Cells, Cultured; Female; Fetus; Gestational Age; Heart; Heart Ventricles; Hyperplasia; Hypertrophy; Mitogen-Activated Protein Kinases; Myocardium; Pregnancy; Sheep; Ventricular Function | 2003 |
NAD(P)H oxidase mediates angiotensin II-induced vascular macrophage infiltration and medial hypertrophy.
Topics: Aldehydes; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Chemotaxis, Leukocyte; Enzyme Inhibitors; Gene Expression Regulation; Glycoproteins; Hypertrophy; Intercellular Adhesion Molecule-1; Macrophages; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Single-Blind Method; Tunica Intima; Tunica Media; Vasculitis | 2003 |
Inflammation and vascular hypertrophy induced by angiotensin II: role of NADPH oxidase-derived reactive oxygen species independently of blood pressure elevation?
Topics: Angiotensin II; Animals; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glycoproteins; Humans; Hypertrophy; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Protein Subunits; Rats; Reactive Oxygen Species; Superoxides; Vasculitis | 2003 |
Angiotensin II-induced hypertrophy of proximal tubular cells requires p27Kip1.
Topics: Angiotensin II; Animals; Apoptosis; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; G1 Phase; Hypertrophy; Kidney Tubules, Proximal; Mice; Mice, Knockout; Proto-Oncogene Proteins; Tumor Suppressor Proteins | 2003 |
c-Src and smooth muscle NAD(P)H oxidase: assembling a path to hypertrophy.
Topics: Angiotensin II; Enzyme Activation; Humans; Hypertrophy; Muscle, Smooth, Vascular; NADPH Oxidases; Neovascularization, Physiologic; Proto-Oncogene Proteins pp60(c-src); Reactive Oxygen Species | 2003 |
Angiotensin II mediates LDL-induced superoxide generation in mesangial cells.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cell Division; Cells, Cultured; Enzyme Inhibitors; Glomerular Mesangium; Humans; Hypertrophy; Lipoproteins, LDL; Losartan; NADPH Oxidases; Onium Compounds; Receptor, Angiotensin, Type 1; RNA, Messenger; Superoxides | 2003 |
Involvement of transforming growth factor-beta in regulation of calcium transients in diabetic vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antibodies; Aorta; Calcium; Calcium Channels; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypertrophy; Inositol 1,4,5-Trisphosphate Receptors; Kidney Glomerulus; Microcirculation; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cytoplasmic and Nuclear; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Angiotensin II and AT1 receptor in hypertrophied ventricles and aortas of sinoaortic-denervated rats.
Topics: Angiotensin II; Animals; Aorta; Denervation; Heart Ventricles; Hypertrophy; Hypertrophy, Left Ventricular; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Sinoatrial Node | 2003 |
In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelium, Vascular; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Isoprostanes; Proteinuria; Rats; Rats, Inbred Dahl; Sodium Chloride; Superoxides; Tetrazoles; Up-Regulation; Vasodilation | 2003 |
Insulin and losartan reduce proteinuria and renal hypertrophy in the pregnant diabetic rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Female; Hypertrophy; Hypoglycemic Agents; Insulin; Kidney; Losartan; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy in Diabetics; Proteinuria; Rats | 2003 |
Phosphatidylinositol 3-kinase in angiotensin II-induced hypertrophy of vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertrophy; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley | 2003 |
Ultrastructural changes in the remnant kidney (after 5/6 nephrectomy) glomerulus after losartan and atenolol treatment.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atenolol; Basement Membrane; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Hypertrophy; Kidney Failure, Chronic; Kidney Glomerulus; Losartan; Male; Microscopy, Electron; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Systole; Time Factors | 2003 |
Inhibitory effect of resveratrol on angiotensin II-induced cardiomyocyte hypertrophy.
Topics: Acetylcysteine; Angiotensin II; Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Hypertrophy; Leucine; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Cardiac; Myosin Heavy Chains; Phosphorylation; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Transfection; Ventricular Myosins | 2004 |
Obligatory role for endogenous endothelin in mediating the hypertrophic effects of phenylephrine and angiotensin II in neonatal rat ventricular myocytes: evidence for two distinct mechanisms for endothelin regulation.
Topics: Angiotensin II; Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Gene Expression; Heart Ventricles; Hypertrophy; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Muscle Cells; Myocardium; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin | 2004 |
Myocardin and Prx1 contribute to angiotensin II-induced expression of smooth muscle alpha-actin.
Topics: Actins; Angiotensin II; Animals; Aorta; Cells, Cultured; Gene Expression Regulation; Genes, Reporter; Homeodomain Proteins; Hypertrophy; Mice; Muscle, Smooth, Vascular; Mutagenesis, Site-Directed; Nuclear Proteins; Rats; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; RNA, Small Interfering; Serum Response Factor; Trans-Activators; Transcription, Genetic; Two-Hybrid System Techniques | 2004 |
Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells.
Topics: Angiotensin II; Animals; Arachidonic Acid; Cells, Cultured; Enzyme Activation; Glomerular Mesangium; Hypertrophy; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NADPH Oxidase 4; NADPH Oxidases; Oxidation-Reduction; Peptide Biosynthesis; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species | 2004 |
Tissue angiotensin-converting enzyme in imposed and physiological flow-related arterial remodeling in mice.
Topics: Alleles; Angiotensin II; Animals; Arteries; Carotid Arteries; Female; Hemorheology; Hyperplasia; Hypertrophy; Ligation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A; Postpartum Period; Pregnancy; Protein Structure, Tertiary; Sequence Deletion; Stress, Mechanical; Uterus | 2004 |
KLF5/BTEB2, a Krüppel-like zinc-finger type transcription factor, mediates both smooth muscle cell activation and cardiac hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Cells, Cultured; Chromatin; Down-Regulation; Echocardiography; Extracellular Matrix; Fibrosis; HeLa Cells; Heterozygote; Homozygote; Humans; Hypertrophy; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; Myocardium; Myosin Heavy Chains; Phenotype; Platelet-Derived Growth Factor; Precipitin Tests; Promoter Regions, Genetic; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Trans-Activators; Transcription, Genetic; Up-Regulation | 2003 |
Effect of irbesartan on angiotensin II-induced hypertrophy of human proximal tubular cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cell Cycle; Cells, Cultured; Humans; Hypertrophy; Irbesartan; Kidney Tubules, Proximal; Protein Biosynthesis; Tetrazoles | 2004 |
Profibrotic effects of angiotensin II in the heart: a matter of mediators.
Topics: Angiotensin II; Animals; Collagen Type I; Collagen Type III; Fibrosis; Humans; Hypertrophy; Mice; Mice, Knockout; Myocardium; Myocytes, Cardiac; Osteopontin; Sialoglycoproteins; Ventricular Remodeling | 2004 |
Cardiovascular hypertrophy in one-kidney, one-clip renal hypertension is resistant to heparin.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Cell Division; DNA; Heparin; Hypertension, Renal; Hypertrophy; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Organ Size; Rats; Rats, Inbred WKY; Time Factors | 2004 |
Cyclin-dependent kinase inhibitor, p21Waf1, regulates vascular smooth muscle cell hypertrophy.
Topics: Adenoviridae; Angiotensin II; Animals; Aorta, Thoracic; Blood Proteins; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Fetal Proteins; Gene Transfer Techniques; Hyperplasia; Hypertension; Hypertrophy; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tumor Suppressor Proteins; Vasoconstrictor Agents | 2004 |
Microtubules regulate angiotensin II type 1 receptor and Rac1 localization in caveolae/lipid rafts: role in redox signaling.
Topics: Angiotensin II; Animals; Aorta; Caveolae; Epidermal Growth Factor; ErbB Receptors; Hydrogen Peroxide; Hypertrophy; Membrane Microdomains; Microtubules; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nocodazole; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1 | 2004 |
Essential role of vascular endothelial growth factor in angiotensin II-induced vascular inflammation and remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cell Division; Chemokine CCL2; Coronary Vessels; DNA-Binding Proteins; Extracellular Matrix Proteins; Gene Expression Profiling; Genetic Therapy; Hypertrophy; Hypertrophy, Left Ventricular; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Myosin Heavy Chains; Natriuretic Peptide, Brain; Nonmuscle Myosin Type IIB; Nuclear Proteins; Olmesartan Medoxomil; Receptors, CCR2; Receptors, Chemokine; Recombinant Fusion Proteins; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tunica Media; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vasculitis; Ventricular Remodeling | 2004 |
Gene transfer of NAD(P)H oxidase inhibitor to the vascular adventitia attenuates medial smooth muscle hypertrophy.
Topics: Adenoviridae; Aldehydes; Angiotensin II; Animals; Blood Pressure; Carotid Arteries; Defective Viruses; Genes, Reporter; Genetic Therapy; Genetic Vectors; Glycoproteins; Hypertrophy; Injections, Intra-Arterial; Lipid Peroxidation; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Reactive Oxygen Species; Tunica Media | 2004 |
Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Drug Synergism; Hypertrophy; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; Vasoconstrictor Agents | 2005 |
Transforming growth factor-beta induces the expression of ANF and hypertrophic growth in cultured cardiomyoblast cells through ZAK.
Topics: Actins; Angiotensin II; Animals; Anthracenes; Atrial Natriuretic Factor; Cell Size; Cells, Cultured; Humans; Hypertrophy; Interleukins; MAP Kinase Kinase 7; MAP Kinase Kinase Kinases; Myocytes, Cardiac; Phenylephrine; Protein Kinase Inhibitors; Protein Kinases; Rats; Recombinant Fusion Proteins; Signal Transduction; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2004 |
[Role of connective tissue growth factor in angiotensin II induced human proximal tubular cell hypertrophy].
Topics: Angiotensin II; Cell Line; Connective Tissue Growth Factor; Endothelial Cells; Humans; Hypertrophy; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney Tubules, Proximal | 2004 |
Angiotensin AT2 receptor contributes to cardiovascular remodelling of aged rats during chronic AT1 receptor blockade.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Fibrosis; Heart Rate; Hypertrophy; Imidazoles; Myocardium; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Telemetry; Tetrazoles; Ventricular Remodeling | 2004 |
Development of a substrate of atrial fibrillation during chronic atrioventricular block in the goat.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Fibrillation; Atrial Natriuretic Factor; Cardiac Pacing, Artificial; Cardiomegaly; Cell Size; Chronic Disease; Connexin 43; Connexins; Female; Gap Junction alpha-5 Protein; Goats; Heart Block; Heart Conduction System; Hemodynamics; Hypertrophy; Myocytes, Cardiac; Neural Conduction; Norepinephrine; Refractory Period, Electrophysiological | 2005 |
Role of interleukin-6 in cardiomyocyte/cardiac fibroblast interactions during myocyte hypertrophy and fibroblast proliferation.
Topics: Angiotensin II; Animals; Antigens, CD; Cell Proliferation; Cells, Cultured; Cytokine Receptor gp130; Fibroblasts; Hypertrophy; Interleukin-6; Membrane Glycoproteins; Mice; Myocardium; Myocytes, Cardiac; Receptor, Angiotensin, Type 1; Tissue Distribution | 2005 |
Resistance to oxidative stress by chronic infusion of angiotensin II in mouse kidney is not mediated by the AT2 receptor.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Blood Pressure; Female; Free Radicals; Gene Expression; Hematocrit; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hypertension, Renal; Hypertrophy; Kidney Cortex; Membrane Proteins; Mice; Mice, Inbred C57BL; NADPH Oxidases; Nitrates; Nitrites; Oxidative Stress; Receptor, Angiotensin, Type 2; Vasoconstrictor Agents | 2005 |
Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1.
Topics: Angiotensin II; Animals; Animals, Newborn; Calcineurin; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Endothelin-1; Estradiol; Estrogens; Extracellular Signal-Regulated MAP Kinases; Hypertrophy; Intracellular Signaling Peptides and Proteins; Leucine; Microscopy, Fluorescence; Models, Biological; Muscle Proteins; Myocytes, Cardiac; Nitric Oxide Synthase; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Time Factors; Transcription, Genetic | 2005 |
Caveolin-1 is essential for activation of Rac1 and NAD(P)H oxidase after angiotensin II type 1 receptor stimulation in vascular smooth muscle cells: role in redox signaling and vascular hypertrophy.
Topics: Actin Cytoskeleton; Angiotensin II; Animals; Caveolin 1; Cells, Cultured; ErbB Receptors; Hypertrophy; Membrane Microdomains; Muscle, Smooth, Vascular; NADPH Oxidases; Oxidation-Reduction; Phosphorylation; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; RNA, Small Interfering; Signal Transduction; SOS1 Protein; Tyrosine; Vasoconstrictor Agents | 2005 |
Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Blood Vessels; Glucosephosphate Dehydrogenase Deficiency; Hypertension; Hypertrophy; Male; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Phosphorylation; Proto-Oncogene Proteins c-akt; Superoxides | 2005 |
ANG II stimulates phospholipase D through PKCzeta activation in VSMC: implications in adhesion, spreading, and hypertrophy.
Topics: 1-Butanol; Angiotensin II; Animals; Cell Adhesion; Enzyme Activation; Hypertrophy; Male; Muscle, Smooth, Vascular; Phospholipase D; Protein Kinase C; Rats; Rats, Sprague-Dawley | 2006 |
Leptin induces vascular smooth muscle cell hypertrophy through angiotensin II- and endothelin-1-dependent mechanisms and mediates stretch-induced hypertrophy.
Topics: Angiotensin II; Animals; Cell Culture Techniques; Cells, Cultured; Culture Media; Endothelin-1; Hypertrophy; Leptin; Male; Models, Biological; Muscle, Smooth, Vascular; Organ Size; Portal Vein; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Leptin; Stress, Mechanical; Up-Regulation | 2005 |
cAbl tyrosine kinase mediates reactive oxygen species- and caveolin-dependent AT1 receptor signaling in vascular smooth muscle: role in vascular hypertrophy.
Topics: Angiotensin II; Animals; ErbB Receptors; Hypertrophy; Intracellular Signaling Peptides and Proteins; Membrane Microdomains; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-abl; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Transcriptional Activation | 2005 |
Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2.
Topics: Angiotensin II; Animals; Aorta; Catalase; Humans; Hydrogen Peroxide; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Messenger; Vasoconstrictor Agents | 2005 |
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice.
Topics: Angiotensin II; Animals; Genes, Reporter; Green Fluorescent Proteins; Humans; Hypertension; Hypertrophy; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; NADPH Oxidase 1; NADPH Oxidases | 2005 |
Connective tissue growth factor-mediated angiotensin II-induced hypertrophy of proximal tubular cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Cell Cycle; Cell Line; Cells, Cultured; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Humans; Hypertrophy; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Irbesartan; Kidney; Kidney Tubules, Proximal; Male; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles | 2006 |
Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Collagen; Ectodysplasins; Fibrosis; Heart; Hypertension; Hypertrophy; Macrophages; Male; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Myocarditis; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Spironolactone; Transcription Factor AP-1; Tumor Necrosis Factors; Vascular Cell Adhesion Molecule-1 | 2005 |
Modulation of action potential duration on myocyte hypertrophic pathways.
Topics: Action Potentials; Angiotensin II; Animals; Calcineurin; Gene Transfer Techniques; Green Fluorescent Proteins; Hypertrophy; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Shal Potassium Channels; Signal Transduction; Sodium-Calcium Exchanger | 2006 |
Role of EGF receptor activation in angiotensin II-induced renal epithelial cell hypertrophy.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Cell Cycle Proteins; DNA, Complementary; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Gene Expression Regulation; Hypertrophy; Kidney Diseases; Models, Biological; Phosphoproteins; Ribosomal Protein S6; Swine; Transcriptional Activation; Transforming Growth Factor beta1 | 2006 |
Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy.
Topics: Adenoviridae; Angiotensin II; Animals; Animals, Newborn; Blotting, Western; Cell Line; Cells, Cultured; Enzyme Activation; Female; Genetic Vectors; Humans; Hypertrophy; Myocytes, Cardiac; NADPH Oxidases; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Superoxide Dismutase; Transfection | 2006 |
Effects of KR-31378, a novel ATP-sensitive potassium channel activator, on hypertrophy of H9c2 cells and on cardiac dysfunction in rats with congestive heart failure.
Topics: Analysis of Variance; Angiotensin II; Animals; Atrial Natriuretic Factor; Blotting, Western; Cell Enlargement; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Guanidines; Heart; Heart Failure; Hypertrophy; Mitogen-Activated Protein Kinases; Myoblasts; Myocardial Infarction; Myocardium; Organ Size; Potassium Channels, Inwardly Rectifying; Protein Precursors; Pyrans; Rats; Rats, Sprague-Dawley | 2006 |
The parathyroid hormone-related protein system and diabetic nephropathy outcome in streptozotocin-induced diabetes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blotting, Western; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epithelial Cells; Gene Expression Regulation; Hypertrophy; Immunohistochemistry; Kidney Tubules; Losartan; Mesangial Cells; Mice; Mice, Transgenic; Parathyroid Hormone-Related Protein; Podocytes; Receptor, Parathyroid Hormone, Type 1 | 2006 |
Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy.
Topics: Angiotensin II; Animals; Apoptosis; Cells, Cultured; Heme Oxygenase-1; Hypertrophy; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Transfection; Up-Regulation | 2006 |
ADAM17 mediates epidermal growth factor receptor transactivation and vascular smooth muscle cell hypertrophy induced by angiotensin II.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Cells, Cultured; ErbB Receptors; Genes, Dominant; Hypertrophy; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; Rats; Receptor, Angiotensin, Type 1; Transcriptional Activation; Transfection | 2006 |
Cardiac energy metabolism alterations in angiotensin II induced hypertrophy.
Topics: Angiotensin II; Animals; Disease Progression; Energy Metabolism; Fatty Acids; Heart Failure; Humans; Hypertrophy; Mice; Models, Biological; Myocardium; Oxygen | 2006 |
FAK-related nonkinase attenuates hypertrophy induced by angiotensin-II in cultured neonatal rat cardiac myocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; DNA, Complementary; Hypertrophy; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factor RelA; Transfection | 2006 |
Activation of endothelial nitric oxide synthase by the angiotensin II type 1 receptor.
Topics: Angiotensin II; Animals; Aorta; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Gene Transfer Techniques; Hypertrophy; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; Transfection | 2006 |
Effects of serum containing Xinlikang on angiotensin ii induced hypertrophy in cultured neonatal rat cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cell Size; Cells, Cultured; DNA; Drugs, Chinese Herbal; Hypertrophy; Myocardial Contraction; Myocytes, Cardiac; Proteins; Rats; Rats, Wistar; Vasoconstrictor Agents | 2006 |
Inhibitory effect of Hsp70 on angiotensin II-induced vascular smooth muscle cell hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Cell Cycle Proteins; Cells, Cultured; Dual Specificity Phosphatase 1; Enzyme Stability; Flavonoids; HSP70 Heat-Shock Proteins; Hypertrophy; Immediate-Early Proteins; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; RNA, Small Interfering | 2006 |
Effect of dominant-negative epidermal growth factor receptors on cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Cells, Cultured; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertrophy; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4 | 2006 |
Involvement of transient receptor potential canonical 1 (TRPC1) in angiotensin II-induced vascular smooth muscle cell hypertrophy.
Topics: Angiotensin II; Cells, Cultured; Coronary Vessels; Humans; Hypertrophy; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; TRPC Cation Channels | 2007 |
Renal sympathetic neuroeffector function in renovascular and angiotensin II-dependent hypertension in rabbits.
Topics: Angiotensin II; Animals; Atrophy; Electric Stimulation; Hypertension; Hypertension, Renovascular; Hypertrophy; Kidney; Male; Medulla Oblongata; Neuroeffector Junction; Norepinephrine; Organ Size; Rabbits; Regional Blood Flow; Renin; Sympathetic Nervous System; Vasoconstrictor Agents | 2007 |
Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Hypertension; Hypertrophy; Interleukin-6; Mice; Myocardium; Receptors, Interleukin-6; Recombinant Fusion Proteins; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation | 2007 |
Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Congenic; Blood Pressure; C-Reactive Protein; Cell Adhesion Molecules; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Membrane Proteins; Ovariectomy; Peptide Fragments; Proteinuria; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 2007 |
Role of alpha1beta1-integrin in arterial stiffness and angiotensin-induced arterial wall hypertrophy in mice.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Carotid Artery, Common; Elasticity; Focal Adhesion Kinase 1; Genotype; Heart Rate; Hypertrophy; Integrin alpha1; Integrin alpha1beta1; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Norepinephrine; p38 Mitogen-Activated Protein Kinases; Phenotype; Phosphorylation; Rupture; Tensile Strength; Vasoconstrictor Agents | 2007 |
Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Histone Deacetylases; Hypertrophy; Male; Myocytes, Smooth Muscle; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction | 2007 |
Different regulation of p27 and Akt during cardiomyocyte proliferation and hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; DNA; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hypertrophy; Immunohistochemistry; Myocardium; Myocytes, Cardiac; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar | 2007 |
IL-6 deficiency protects against angiotensin II induced endothelial dysfunction and hypertrophy.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Carotid Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertrophy; Interleukin-6; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; RNA, Messenger; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2007 |
Functional coupling of angiotensin II type 1 receptor with insulin resistance of energy substrate uptakes in immortalized cardiomyocytes (HL-1 cells).
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line; Cell Survival; Glucose; Hypertrophy; Insulin; Insulin Resistance; Mice; Myocytes, Cardiac; Palmitic Acid; Receptor, Angiotensin, Type 1 | 2008 |
Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension.
Topics: Actins; Adenosine Triphosphate; Angiotensin II; Animals; Arterioles; Blood Pressure; Cell Proliferation; Clopidogrel; Disease Models, Animal; Hypertension; Hypertrophy; Kidney; Male; Membrane Proteins; Mesangial Cells; Purinergic Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Renin; Ticlopidine | 2008 |
[Effects of tetrandrine on Ang II-induced cardiomyocyte hypertrophy and p-ERK1/2 expression].
Topics: Angiotensin II; Animals; Animals, Newborn; Benzylisoquinolines; Blotting, Western; Cell Size; Cells, Cultured; Drugs, Chinese Herbal; Hypertrophy; Immunoprecipitation; Microscopy, Phase-Contrast; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Phosphorylation; Plants, Medicinal; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Signal Transduction; Stephania tetrandra | 2007 |
Gene expression pattern in biomechanically stretched cardiomyocytes: evidence for a stretch-specific gene program.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Animals, Newborn; Gene Expression; Gene Expression Profiling; Genome; Heart Ventricles; Hypertrophy; Microarray Analysis; Myocytes, Cardiac; Phenylephrine; Rats; Receptors, Angiotensin; Signal Transduction; Stress, Mechanical | 2008 |
Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy.
Topics: Angiotensin II; Angiotensinogen; Animals; Apoptosis Regulatory Proteins; Cardiotonic Agents; Casein Kinase II; Catalase; Cell Membrane Permeability; Down-Regulation; Gene Expression Regulation, Enzymologic; Hypertrophy; Mice; Mice, Transgenic; Mitochondria, Heart; Muscle Proteins; Myocytes, Cardiac; Oxidation-Reduction; Phenylephrine; Phosphorylation; Protein Carbonylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2008 |
Novel role of protein kinase C-delta Tyr 311 phosphorylation in vascular smooth muscle cell hypertrophy by angiotensin II.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Aorta; Cells, Cultured; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertrophy; Immunoblotting; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Protein Kinase C-delta; Rats; Receptor, Angiotensin, Type 1; src-Family Kinases; Tyrosine | 2008 |
Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcium-Binding Proteins; Calpain; Cysteine Proteinase Inhibitors; Disease Models, Animal; Fibrosis; Genetic Therapy; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Inflammation; Infusion Pumps, Implantable; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocardium; NF-kappa B; NFATC Transcription Factors; Renal Artery; Time Factors; Ventricular Remodeling | 2008 |
Suppression of cardiac myocyte hypertrophy by conjugated linoleic acid: role of peroxisome proliferator-activated receptors alpha and gamma.
Topics: Angiotensin II; Animals; Dietary Supplements; Diglycerides; Endothelin-1; Fibroblast Growth Factors; Hypertrophy; Linoleic Acids, Conjugated; Models, Biological; Myocytes, Cardiac; PPAR alpha; PPAR gamma; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley | 2008 |
Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca2+ signal integrators.
Topics: Aldosterone; Angiotensin II; Animals; Calcineurin; Calcium; Cells, Cultured; DNA, Complementary; Hypertrophy; Myocytes, Cardiac; NFATC Transcription Factors; Norepinephrine; Potassium Chloride; Protein Transport; Rats; Rats, Wistar; Signal Transduction | 2008 |
Epigenetic regulation of cardiac muscle-specific genes in H9c2 cells by Interleukin-18 and histone deacetylase inhibitor m-carboxycinnamic acid bis-hydroxamide.
Topics: Angiotensin II; Cardiotonic Agents; Cell Line; Cinnamates; Epigenesis, Genetic; Gene Expression Regulation; Heart; Histone Code; Histone Deacetylase Inhibitors; Humans; Hypertrophy; Interleukin-18; Myocardium; Organ Specificity; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphorylation; PTEN Phosphohydrolase; Ventricular Myosins | 2008 |
Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.
Topics: Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Western; Diuretics; Epithelial Sodium Channels; Furosemide; Hypertrophy; Kidney Tubules, Proximal; Male; Obesity; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Receptors, Drug; Renin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Phosphate Cotransporter Proteins, Type IIb; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Solute Carrier Family 12, Member 3; Symporters; Tetrazoles | 2008 |
Central role of Gq in the hypertrophic signal transduction of angiotensin II in vascular smooth muscle cells.
Topics: Adenoviridae; Angiotensin II; Animals; Calcium; Cell Enlargement; Cell Proliferation; Cells, Cultured; Cyclic AMP; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertrophy; Immunoblotting; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Fragments; Phosphorylation; Protein Phosphatase 1; Rats; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Signal Transduction | 2008 |
Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Benzoates; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Fibrosis; Heart Rate; Hypertension; Hypertrophy; Kidney; Losartan; Male; Myocardium; Organ Specificity; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium, Dietary; Telmisartan | 2008 |
A novel signaling pathway of ADP-ribosyl cyclase activation by angiotensin II in adult rat cardiomyocytes.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Angiotensin II; Animals; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclic ADP-Ribose; Enzyme Activation; Hypertrophy; Inositol 1,4,5-Trisphosphate Receptors; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; NFATC Transcription Factors; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ryanodine Receptor Calcium Release Channel; src-Family Kinases; Time Factors; Transforming Growth Factor beta1 | 2008 |
Vascular smooth muscle in hypertension.
Topics: Angiotensin II; Animals; Calcium; Cations; Cats; Cell Membrane Permeability; Hypertension; Hypertrophy; In Vitro Techniques; Ion Channels; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Swine; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1982 |
The role of vascular hypertrophy in early and chronic renovascular hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Blood Pressure; Chronic Disease; Female; Hypertension, Renovascular; Hypertrophy; Norepinephrine; Perfusion; Rats; Rats, Inbred Strains; Renal Artery | 1983 |
[Functional and structural vascular reactions following intermittent administration of angiotensin in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Hyperplasia; Hypertension; Hypertrophy; Male; Rats; Rats, Inbred Strains | 1983 |
Does the rapidity with which hypertension reverses on unclipping a clipped kidney and on stopping long-term infusion of angiotensin II make unlikely an important role for vascular hypertrophy in maintaining the hypertension seen before reversal?
Topics: Angiotensin II; Animals; Blood Vessels; Constriction; Humans; Hypertension; Hypertension, Renovascular; Hypertrophy; Time Factors | 1995 |
Effects of an angiotensin II receptor antagonist, CV-11974, on angiotensin II-induced increases in cytosolic free calcium concentration, hyperplasia, and hypertrophy of cultured vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Calcium; Cells, Cultured; Cytosol; Dinoprost; DNA; Fura-2; Hyperplasia; Hypertrophy; Ionomycin; Muscle Proteins; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tetrazoles | 1994 |
Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor.
Topics: Angiotensin II; Animals; Casein Kinase II; Cells, Cultured; DNA-Binding Proteins; Hypertrophy; Muscle, Smooth, Vascular; Phosphorylation; Pol1 Transcription Initiation Complex Proteins; Protein Serine-Threonine Kinases; Rats; RNA, Ribosomal, 18S; Serine; Transcription Factors; Transcription, Genetic | 1995 |
Angiotensin II induces cardiovascular hypertrophy in perindopril-treated rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arterioles; Cardiovascular System; Hypertrophy; Indoles; Male; Muscle, Smooth, Vascular; Perindopril; Ploidies; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation | 1995 |
Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney.
Topics: Angiotensin II; Animals; Base Sequence; Disease Progression; Endothelium, Vascular; Extracellular Matrix Proteins; Gene Expression Regulation; Glomerulosclerosis, Focal Segmental; Hypertrophy; Kidney Glomerulus; Male; Molecular Sequence Data; Nephrectomy; Rats; Rats, Wistar; Renal Circulation; RNA, Messenger; Transforming Growth Factor beta | 1995 |
Components of the protein synthesis and folding machinery are induced in vascular smooth muscle cells by hypertrophic and hyperplastic agents. Identification by comparative protein phenotyping and microsequencing.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Blood; Cells, Cultured; Chaperonin 60; HSP70 Heat-Shock Proteins; Hyperplasia; Hypertrophy; Isoenzymes; Isomerases; Male; Molecular Sequence Data; Muscle Proteins; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Disulfide-Isomerases; Rats; Rats, Sprague-Dawley | 1995 |
Angiotensin II stimulates cellular hypertrophy of LLC-PK1 cells through the AT1 receptor.
Topics: Angiotensin II; Animals; Cell Division; Cyclic AMP; Growth Substances; Hypertrophy; Kidney Tubules; Proteins; Receptors, Angiotensin; RNA | 1993 |
Identification and antisense inhibition of a renin-angiotensin system in transgenic cardiomyocytes.
Topics: Angiotensin II; Angiotensinogen; Animals; Base Sequence; Blood; Cell Division; Hypertrophy; Mice; Mice, Transgenic; Molecular Sequence Data; Myocardium; Oligonucleotide Probes; Oligonucleotides, Antisense; Polymerase Chain Reaction; Renin-Angiotensin System; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Chronic administration of angiotensin II receptor antagonist, TCV-116, in cardiomyopathic hamsters.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomyopathies; Cricetinae; Guinea Pigs; Hypertrophy; Male; Mesocricetus; Myocardium; Pressure; Renin-Angiotensin System; Tetrazoles; Ventricular Function, Left | 1994 |
Cardiovascular hypertrophy in one-kidney, one clip renal hypertensive rats: a role for angiotensin II?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Body Weight; Cardiomegaly; Hypertension, Renovascular; Hypertrophy; Imidazoles; Indoles; Losartan; Male; Muscle, Smooth, Vascular; Perindopril; Rats; Rats, Inbred WKY; Tetrazoles | 1994 |
Evidence that endogenous somatostatin (SRIF) exerts an inhibitory control on the function and growth of rat adrenal zona glomerulosa. The possible involvement of zona medullaris as a source of endogenous SRIF.
Topics: Adrenal Cortex; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrophy; Hypertrophy; Male; Rats; Rats, Wistar; Somatostatin; Zona Glomerulosa | 1994 |
Vascular aldosterone. Biosynthesis and a link to angiotensin II-induced hypertrophy of vascular smooth muscle cells.
Topics: Aldosterone; Amino Acid Sequence; Angiotensin II; Base Sequence; Cells, Cultured; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme System; DNA Primers; Gene Expression; Humans; Hypertrophy; Molecular Sequence Data; Muscle, Smooth, Vascular; Receptors, Mineralocorticoid; RNA, Messenger; Steroid 11-beta-Hydroxylase | 1994 |
Evidence that endogenous vasoactive intestinal peptide (VIP) plays a role in the maintenance of the growth and steroidogenic capacity of rat adrenal zona glomerulosa.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Hypertrophy; Male; Mitochondria; Rats; Rats, Wistar; Renin; Vasoactive Intestinal Peptide; Zona Glomerulosa | 1994 |
Juxtaglomerular cell hypertrophy and hyperplasia induced in rhesus monkeys by angiotensin II receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Enalapril; Hyperplasia; Hypertrophy; Imidazoles; Immunosuppressive Agents; Juxtaglomerular Apparatus; Losartan; Macaca mulatta; Pyridines; Renin; Tetrazoles; Time Factors | 1994 |
Effect of angiotensin II on human vascular smooth muscle cell growth.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Humans; Hypertrophy; Muscle, Smooth, Vascular; Phosphorylation; Rats; Rats, Sprague-Dawley; Species Specificity; Tyrosine | 1994 |
The role of activated vascular angiotensin II generation in vascular hypertrophy in one-kidney, one clip hypertensive rats.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; DNA; Hydralazine; Hypertension, Renovascular; Hypertrophy; Indans; Male; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tetrazoles | 1993 |
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
Topics: Acridines; Angiotensin II; Animals; Cells, Cultured; Hypertrophy; Multienzyme Complexes; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidases; Rats; Superoxides | 1994 |
[Mechanisms of vascular hypertrophy in hypertension].
Topics: Angiotensin II; Animals; Endothelial Growth Factors; Endothelium, Vascular; Humans; Hypertension; Hypertrophy; Muscle, Smooth, Vascular; Vascular Resistance | 1993 |
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Cytoplasmic Granules; Endothelins; Gene Expression Regulation; Genes, fos; Hypertrophy; In Vitro Techniques; Mechanoreceptors; Myocardium; Peptidyl-Dipeptidase A; Rats; Renin; RNA, Messenger; Stress, Mechanical | 1993 |
Role of the lipoxygenase pathway in angiotensin II-induced vascular smooth muscle cell hypertrophy.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Biphenyl Compounds; Cells, Cultured; Dose-Response Relationship, Drug; Fibronectins; Flavanones; Flavonoids; Hydroxyeicosatetraenoic Acids; Hypertrophy; Ibuprofen; Imidazoles; Lipoxygenase Inhibitors; Losartan; Muscle, Smooth, Vascular; Pyridines; Swine; Tetrazoles | 1994 |
Slow developing pressor effect of angiotensin II and vascular structure.
Topics: Angiotensin II; Animals; Blood Vessels; Growth Substances; Hypertension; Hypertrophy; Rats; Rats, Inbred SHR | 1993 |
Effect of angiotensin II blockade on dietary protein-induced renal growth.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dietary Proteins; Enalapril; Hypertrophy; Imidazoles; Kidney; Losartan; Male; Organ Size; Rats; Rats, Sprague-Dawley; Tetrazoles | 1993 |
Effect of perindopril on cardiovascular hypertrophy of the SHR: respective roles of reduced blood pressure and reduced angiotensin II levels.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Indoles; Male; Muscle, Smooth, Vascular; Perindopril; Rats; Rats, Inbred SHR | 1993 |
Morphology of resistance arteries and comparison of effects of vasoconstrictors in mild essential hypertensive patients.
Topics: Adult; Angiotensin II; Arginine Vasopressin; Arteries; Endothelins; Humans; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Serotonin; Vascular Resistance; Vasoconstrictor Agents | 1993 |
Angiotensin II causes mesangial cell hypertrophy.
Topics: Angiotensin II; Animals; Cell Count; Cell Survival; Cells, Cultured; DNA; Glomerular Mesangium; Hypertrophy; Mice; Protein Biosynthesis; Proteins | 1993 |
Role of transforming growth factor-beta 1 in the cellular growth response to angiotensin II.
Topics: Angiotensin II; Animals; Biological Assay; Cell Division; Cells, Cultured; DNA; Fibroblast Growth Factor 2; Hyperplasia; Hypertrophy; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Transforming Growth Factor beta | 1993 |
Angiotensin-II-induced cell hypertrophy: potential role of impaired proteolytic activity in cultured LLC-PK1 cells.
Topics: Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Cell Count; Cells, Cultured; Cycloheximide; DNA; Hypertrophy; Imidazoles; Kidney; LLC-PK1 Cells; Losartan; Oligopeptides; Protein Synthesis Inhibitors; Proteins; Swine; Tetrazoles; Verapamil | 1995 |
Heparin and heparan sulfate block angiotensin II-induced hypertrophy in cultured neonatal rat cardiomyocytes. A possible role of intrinsic heparin-like molecules in regulation of cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Heart; Heparin; Heparin Lyase; Heparitin Sulfate; Humans; Hypertrophy; Leucine; Myocardium; Polysaccharide-Lyases; Rats; Recombinant Proteins | 1996 |
Chronic blockade of AT2-subtype receptors prevents the effect of angiotensin II on the rat vascular structure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Collagen; Elastin; Fibrosis; Hypertension; Hypertrophy; Imidazoles; Infusions, Parenteral; Losartan; Male; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Wistar; Reference Values; Tetrazoles | 1996 |
Kinins or nitric oxide, or both, are involved in the antitrophic effects of angiotensin converting enzyme inhibitors on diabetes-associated mesenteric vascular hypertrophy in the rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Bradykinin; Diabetic Angiopathies; Hypertrophy; Indoles; Kinins; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Perindopril; Rats; Rats, Wistar | 1996 |
p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Vessels; Cytochrome b Group; DNA, Antisense; DNA, Complementary; Hydrogen Peroxide; Hypertrophy; Imidazoles; Losartan; Male; Membrane Transport Proteins; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Tetrazoles; Transfection; Vasoconstrictor Agents | 1996 |
Angiotensin II-stimulated hypertrophy of LLC-PK1 cells depends on the induction of the cyclin-dependent kinase inhibitor p27Kip1.
Topics: Angiotensin II; Animals; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; G1 Phase; Hypertrophy; Kidney Tubules, Proximal; LLC-PK1 Cells; Microtubule-Associated Proteins; Swine; Tumor Suppressor Proteins | 1996 |
Angiotensin II and bladder obstruction in the rat: influence on hypertrophic growth and contractility.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Female; Hypertrophy; Imidazoles; Losartan; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Organ Size; Rats; Rats, Sprague-Dawley; Tetrazoles; Urinary Bladder; Urinary Bladder Neck Obstruction | 1996 |
Endothelin-1 regulates normal cardiovascular development and cardiac cellular hypertrophy.
Topics: Amino Acids; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cardiovascular System; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Gene Expression; Hypertrophy; Mice; Mice, Knockout; Myocardium; Peptides, Cyclic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Stress, Mechanical | 1996 |
The effects of high glucose concentration on angiotensin II- or transforming growth factor-beta-induced DNA synthesis, hypertrophy and collagen synthesis in cultured rat mesangial cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Collagen; DNA; Glomerular Mesangium; Glucose; Hypertrophy; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 1996 |
Angiotensin II release from rabbit intrarenal arteries: a critical assessment.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Arteries; Chromium Radioisotopes; Hypertension, Renovascular; Hypertrophy; In Vitro Techniques; Isoproterenol; Kidney; Microspheres; Nephrectomy; Rabbits; Renal Circulation; Renin; Sodium | 1997 |
The influence of angiotensin II-induced increase in aortic wall mass on compliance in rats in vivo.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Hypertrophy; Male; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Ultrasonography; Vascular Resistance | 1997 |
Differential roles of AT1 and AT2 receptor subtypes in vascular trophic and phenotypic changes in response to stimulation with angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Blood Vessels; Coronary Vessels; Hypertrophy; Male; Muscle, Smooth, Vascular; Phenotype; Rats; Rats, Wistar; Receptors, Angiotensin; Tunica Media | 1997 |
Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biphenyl Compounds; Captopril; Cells, Cultured; Hypertension; Hypertrophy; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nifedipine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 1997 |
Angiotensin II increases tissue endothelin and induces vascular hypertrophy: reversal by ET(A)-receptor antagonist.
Topics: Angiotensin II; Animals; Arteries; Basilar Artery; Blood Pressure; Endothelin Receptor Antagonists; Endothelins; Hypertrophy; Mesenteric Arteries; Phenylpropionates; Pyrimidines; Rats; Rats, Inbred WKY; Receptor, Endothelin A | 1997 |
Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihypertensive Agents; Body Weight; Cardiomegaly; Cardiovascular System; Hypertension; Hypertrophy; Indoles; Kidney; Losartan; Male; Mesenteric Arteries; Organ Size; Papaverine; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance | 1997 |
Angiotensin II mediates cell hypertrophy in vascular smooth muscle cultures from hypertensive Ren-2 transgenic rats by an amiloride- and furosemide-sensitive mechanism.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biological Transport; Cell Size; Cells, Cultured; Femoral Artery; Furosemide; Heterozygote; Hypertension; Hypertrophy; Male; Mice; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Sprague-Dawley; Renin; Rubidium | 1997 |
Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cattle; Coculture Techniques; Culture Media, Conditioned; Endothelin Receptor Antagonists; Endothelin-1; Hypertrophy; Lipoproteins, LDL; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Paracrine Communication; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Transforming Growth Factor beta; Ventricular Function | 1997 |
Angiotensin II modulates cell growth-related events and synthesis of matrix proteins in renal interstitial fibroblasts.
Topics: Angiotensin II; Animals; Calcium; Cell Communication; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Fibroblasts; Fibronectins; Fibrosis; Flow Cytometry; Gene Expression Regulation; Hyperplasia; Hypertrophy; Imidazoles; Kidney; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Receptors, Angiotensin; RNA, Messenger; Transforming Growth Factor beta; Up-Regulation | 1997 |
Role of angiotensin II and bradykinin on aortic collagen following converting enzyme inhibition in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Bradykinin; Bradykinin Receptor Antagonists; Collagen; Drug Therapy, Combination; Hemodynamics; Hypertension; Hypertrophy; Imidazoles; Isoquinolines; Male; Quinapril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Tetrahydroisoquinolines; Tetrazoles | 1997 |
Effect of taurine on angiotensin II-induced hypertrophy of neonatal rat cardiac cells.
Topics: Angiotensin II; Animals; Animals, Newborn; Genes, Immediate-Early; Heart; Hyperplasia; Hypertrophy; Myocardium; Rats; Rats, Wistar; Taurine | 1997 |
The effects of angiotensin II and specific angiotensin receptor blockers on embryonic cardiac development and looping patterns.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiomegaly; Fetal Heart; Fibroblasts; Heart Ventricles; Hypertrophy; Imidazoles; Losartan; Morphogenesis; Myocardium; Myosin Heavy Chains; Organ Culture Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1997 |
Adrenomedullin: a possible autocrine or paracrine inhibitor of hypertrophy of cardiomyocytes.
Topics: Adrenomedullin; Angiotensin II; Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Cattle; Cells, Cultured; Culture Media, Serum-Free; Heart; Humans; Hypertrophy; Kinetics; Myocardium; Peptide Fragments; Peptides; Phenylalanine; Rats; Rats, Wistar; RNA, Messenger; Serum Albumin, Bovine; Transcription, Genetic | 1998 |
Renal growth and development in mice lacking AT1A receptors for angiotensin II.
Topics: Angiotensin II; Animals; Arterioles; Atrophy; Crosses, Genetic; Glomerular Mesangium; Heterozygote; Hypertrophy; Juxtaglomerular Apparatus; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renal Circulation; Renin | 1998 |
Effect of neonatal sympathectomy on the development of structural vascular changes in angiotensin II-treated rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Hypertension; Hypertrophy; Male; Mesenteric Arteries; Rats; Rats, Sprague-Dawley; Sympathectomy; Sympathetic Nervous System | 1998 |
Endogenous angiotensin II and cell hypertrophy in vascular smooth muscle cultures from hypertensive Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cell Division; Cell Size; Cells, Cultured; Disease Models, Animal; Femoral Artery; Gene Expression Regulation; Genes, fos; Genes, jun; Hypertension; Hypertrophy; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Renin; Tunica Media | 1998 |
Effect of chronic nitric oxide deficiency on angiotensin II-induced hypertrophy of rat basilar artery.
Topics: Analysis of Variance; Angiotensin II; Animals; Basilar Artery; Blood Pressure; Body Weight; Enzyme Inhibitors; Hypertrophy; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organ Size; Rats; Rats, Inbred WKY; Systole; Vasoconstrictor Agents; Weight Gain | 1998 |
Angiotensin II induces hypertrophy of human airway smooth muscle cells: expression of transcription factors and transforming growth factor-beta1.
Topics: Angiotensin II; Blotting, Northern; Bronchi; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Humans; Hyperplasia; Hypertrophy; Immediate-Early Proteins; Immunohistochemistry; Muscle, Smooth; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Time Factors; Transcription Factors; Transforming Growth Factor beta | 1998 |
Angiotensin II induces vascular smooth muscle cell replication independent of blood pressure.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Cell Division; Data Interpretation, Statistical; DNA Replication; Hydralazine; Hyperplasia; Hypertrophy; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley | 1998 |
Heparin inhibits mesenteric vascular hypertrophy in angiotensin II-infusion hypertension in rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Fibrinolytic Agents; Heparin; Hypertension; Hypertrophy; Male; Mesenteric Veins; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Vasoconstrictor Agents | 1998 |
Pressure mediates angiotensin II-induced arterial hypertrophy and PDGF-A expression.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Antimetabolites; Blood Pressure; Bromodeoxyuridine; Drug Interactions; Hypertrophy; In Situ Hybridization; Male; Minoxidil; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Vasoconstrictor Agents | 1998 |
Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy.
Topics: Angiotensin II; Animals; Catalase; Cells, Cultured; Hydrogen Peroxide; Hypertrophy; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; Oxidants; Rats; RNA, Messenger; Superoxide Dismutase; Vasoconstrictor Agents | 1998 |
Mechanism of hyperthyroidism-induced renal hypertrophy in rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Gene Expression; Hyperthyroidism; Hypertrophy; Kidney; Losartan; Male; Nicardipine; Rats; Rats, Sprague-Dawley; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thyroxine | 1998 |
Angiotensin II-mediated expression of p27Kip1 and induction of cellular hypertrophy in renal tubular cells depend on the generation of oxygen radicals.
Topics: Angiotensin II; Animals; Cell Cycle Proteins; Cell Line; Cyclin-Dependent Kinase Inhibitor p27; Hypertrophy; Kidney Tubules, Proximal; LLC-PK1 Cells; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Microtubule-Associated Proteins; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; Rats; Reactive Oxygen Species; Superoxides; Swine; Tumor Suppressor Proteins | 1998 |
Differential regulation of p27kip1 levels and CDK activities by hypertrophic and hyperplastic agents in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Becaplermin; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; DNA; G1 Phase; Hyperplasia; Hypertrophy; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; Phosphorylation; Platelet-Derived Growth Factor; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Rats; Retinoblastoma Protein; S Phase; Signal Transduction; Tumor Suppressor Proteins | 1999 |
Production of angiotensin II by homogeneous cultures of vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Benzimidazoles; Biphenyl Compounds; Cathepsin D; Cathepsin E; Cell Division; Cells, Cultured; Culture Media, Conditioned; Hyperplasia; Hypertension; Hypertrophy; Indans; Kallikreins; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Tissue Kallikreins | 1999 |
Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Enzyme Activation; Hydrogen Peroxide; Hypertrophy; Male; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; Onium Compounds; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 1999 |
Cell cycle inhibitors (p27Kip1 and p21CIP1) cause hypertrophy in LLC-PK1 cells.
Topics: Adenoviridae; Angiotensin II; Animals; beta-Galactosidase; Carrier Proteins; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Size; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Viral; Genetic Vectors; Hypertrophy; Kidney Diseases; LLC-PK1 Cells; Microtubule-Associated Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Swine; Tritium; Tumor Suppressor Proteins; Vasoconstrictor Agents | 1999 |
Pressure but not angiotensin II-induced increases in wall mass or tone influences static and dynamic aortic mechanics.
Topics: Angiotensin II; Animals; Aorta; Biomechanical Phenomena; Blood Pressure; Compliance; Hypertrophy; Male; Muscle, Smooth, Vascular; Organ Size; Rats; Rats, Wistar; Vascular Resistance | 1999 |
Role of angiotensin receptor subtypes in mesenteric vascular proliferation and hypertrophy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Hypertrophy; Immunohistochemistry; Male; Mesenteric Arteries; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1999 |
A novel role for the cyclin-dependent kinase inhibitor p27(Kip1) in angiotensin II-stimulated vascular smooth muscle cell hypertrophy.
Topics: Angiotensin II; Animals; Cell Cycle; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Hypertrophy; Male; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Tumor Suppressor Proteins | 1999 |
Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen: evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin II.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Newborn; Captopril; Cells, Cultured; Culture Media, Serum-Free; Enzyme Precursors; Fibroblasts; Hypertrophy; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin; Stress, Mechanical | 1999 |
Involvement of Rho-kinase in angiotensin II-induced hypertrophy of rat vascular smooth muscle cells.
Topics: ADP Ribose Transferases; Amides; Angiotensin II; Animals; Aorta, Thoracic; Biological Transport; Botulinum Toxins; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Gene Expression; Hypertrophy; Intracellular Signaling Peptides and Proteins; Leucine; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Ribosomal Protein S6 Kinases; RNA, Messenger | 2000 |
Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy.
Topics: Adenoviridae; Angiotensin II; Animals; Apoptosis Regulatory Proteins; Atrial Natriuretic Factor; Calcineurin; Calcineurin Inhibitors; Cardiomegaly; Carrier Proteins; Cattle; Cells, Cultured; DNA-Binding Proteins; Fetal Blood; Gene Expression Regulation; Genes; Genetic Therapy; Genetic Vectors; Hypertrophy; Myocardium; NFATC Transcription Factors; Nuclear Proteins; Phenylephrine; Rats; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transfection | 2000 |
Reactive oxygen species stimulate p44/42 mitogen-activated protein kinase and induce p27(Kip1): role in angiotensin II-mediated hypertrophy of proximal tubular cells.
Topics: Angiotensin II; Animals; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Inhibitors; Flavonoids; Hydrogen Peroxide; Hypertrophy; Kidney Tubules, Proximal; LLC-PK1 Cells; Mice; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Phosphorylation; Reactive Oxygen Species; Swine; Tumor Suppressor Proteins | 2000 |
CC chemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Biomarkers; Cell Movement; Endothelium, Vascular; Hypertension; Hypertrophy; Macrophages; Mice; Mice, Inbred C57BL; Receptor, Macrophage Colony-Stimulating Factor; Receptors, CCR2; Receptors, Chemokine; Vasculitis; Vasoconstrictor Agents | 2000 |
[Cardiac and vascular hypertrophy in hypertension due to angiotensin II. Effect of losartan and bosentan].
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Carotid Arteries; Endothelin Receptor Antagonists; Endothelins; Follow-Up Studies; Hypertension; Hypertrophy; Losartan; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sulfonamides | 2000 |
Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization.
Topics: Angiotensin II; Animals; Aorta; Hypertension; Hypertrophy; Mesenteric Arteries; Muscle, Smooth, Vascular; Mutagens; Polyploidy; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Zucker; Recombinant Proteins; Up-Regulation | 2000 |
Involvement of angiotensin II and endothelin-1 in the development of submandibular gland hypertrophy in response to isoproterenol in rats.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Dobutamine; Enalapril; Endothelin-1; Hypertrophy; Isoproterenol; Male; Rats; Rats, Wistar; Submandibular Gland | 2000 |
Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression; Hypertrophy; Hypoglycemic Agents; Insulin; Kidney Tubules, Proximal; Losartan; Male; Nephritis, Interstitial; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger | 2000 |
ANG II is required for optimal overload-induced skeletal muscle hypertrophy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrophy; Drinking; Eating; Female; Hypertrophy; Muscle Proteins; Muscle, Skeletal; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Stress, Mechanical; Vasoconstrictor Agents; Weight-Bearing | 2001 |
A role for PYK2 in regulation of ERK1/2 MAP kinases and PI 3-kinase by ANG II in vascular smooth muscle.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Calcium; Cells, Cultured; Chromones; Crk-Associated Substrate Protein; Enzyme Inhibitors; Focal Adhesion Kinase 2; GRB2 Adaptor Protein; Hypertrophy; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Retinoblastoma-Like Protein p130; Ribosomal Protein S6 Kinases; Signal Transduction; src-Family Kinases | 2001 |
ANG II potentiates mitogenic effect of norepinephrine in vascular muscle cells: role of FGF-2.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Cell Count; Cell Division; Cells, Cultured; Drug Synergism; Enzyme Activation; Fibroblast Growth Factor 2; Growth Substances; Hypertrophy; Inositol Phosphates; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Vasoconstrictor Agents | 2001 |
Arterial remodeling in chronic sinoaortic-denervated rats.
Topics: Angiotensin II; Animals; Aorta; Arteries; Blood Pressure; Carotid Sinus; Denervation; Heart Rate; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 2001 |
Arachidonic acid metabolites mediate angiotensin II-induced NADH/NADPH oxidase activity and hypertrophy in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arachidonic Acid; Cells, Cultured; Enzyme Activation; Hypertrophy; Intracellular Fluid; Membrane Transport Proteins; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Phospholipases A; Phospholipases A2; Phosphoproteins; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Transfection | 1999 |
Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blood Vessels; Body Weight; Genotype; Hypertrophy; Immunohistochemistry; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; RNA, Messenger; Superoxides; Tyrosine | 2001 |
Atrial natriuretic peptide attenuates ANG II-induced hypertrophy of renal tubular cells.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cell Line; Hypertrophy; Kidney Tubules; Mitogen-Activated Protein Kinases; Oligonucleotides, Antisense; Phosphorylation; Protein Tyrosine Phosphatases; Superoxides; Swine; Transfection | 2001 |
Transient involvement of endothelin in hypertrophic remodeling of small arteries.
Topics: Angiotensin II; Animals; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hypertrophy; Mesenteric Arteries; Norepinephrine; Phenylpropionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Resistance | 2001 |
Inhibitory effect of quercetin on cultured neonatal rat cardiomyocytes hypertrophy induced by angiotensin.
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Hypertrophy; Myocardium; Myocytes, Cardiac; Protein Kinase C; Protein-Tyrosine Kinases; Quercetin; Rats; Rats, Wistar | 2001 |
[The role of AT1 receptor and cyclin kinase inhibitor p27 protein in angiotensin II-induced hypertrophy of mesangial cell].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Glomerular Mesangium; Hypertrophy; Losartan; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tumor Suppressor Proteins | 2001 |
Angiotensin II induced cardiac hypertrophy in vivo is inhibited by cyclosporin A in adult rats.
Topics: Angiotensin II; Animals; Blotting, Northern; Body Weight; Calcineurin; Calcium; Cardiomegaly; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hypertrophy; Myocardium; Organ Size; Rats; Rats, Wistar; RNA; Signal Transduction; Up-Regulation | 2001 |
The oxidized lipid and lipoxygenase product 12(S)-hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angiotensin II
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Angiotensin II; Animals; Cell Nucleus; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Hypertrophy; Imidazoles; Immunoblotting; Lipid Metabolism; Lipoxygenase; Luciferases; Mice; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oxygen; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Transport; Pyridines; ras Proteins; Signal Transduction; Swine; Time Factors; Transcription, Genetic; Transfection | 2002 |
[The role of cyclin-dependent kinase inhibitors in hyperplasia and hypertrophy of vascular smooth muscle cells].
Topics: Angiotensin II; Animals; Becaplermin; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Cyclins; Disease Models, Animal; Gene Expression; Hyperplasia; Hypertrophy; Male; Muscle, Smooth, Vascular; Nuclear Proteins; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Tumor Suppressor Proteins | 2001 |
Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blood Vessels; Gene Expression; Humans; Hypertrophy; Immunohistochemistry; Luminescent Measurements; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidases; Oxidative Stress; Superoxide Dismutase; Superoxides; Tyrosine | 2002 |
The hypertrophic response in C2C12 myoblasts recruits the G1 cell cycle machinery.
Topics: Angiotensin II; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; G1 Phase; Histone Deacetylases; Hypertrophy; Microfilament Proteins; Muscle Proteins; Muscle, Skeletal; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Retinoblastoma Protein; Transcription Factors | 2002 |
[Morphologic studies of the juxtaglomerular apparatus of the rat treated with furosemide].
Topics: Angiotensin II; Animals; Furosemide; Hyperplasia; Hypertrophy; Juxtaglomerular Apparatus; Kidney; Rats; Renin | 1977 |
Na+, K(+)-adenosine triphosphatase regulation in hypertrophied vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Homeostasis; Hypertrophy; Muscle Proteins; Muscle, Smooth, Vascular; Osmolar Concentration; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase | 1992 |
The effect of angiotensin II on DNA synthesis varies considerably in vascular smooth muscle cells from different Wistar-Kyoto rats.
Topics: Angiotensin II; Animals; Cell Line; DNA; Dose-Response Relationship, Drug; Female; Hypertrophy; Mitosis; Muscle Development; Muscle, Smooth, Vascular; Protein Biosynthesis; Rats; Rats, Inbred WKY | 1992 |
Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Hydralazine; Hypertension; Hypertrophy; Indans; Male; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 1992 |
Regulation of S6 kinase activity in renal proximal tubule.
Topics: Angiotensin II; Animals; Cells, Cultured; Epidermal Growth Factor; Hypertrophy; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Proximal; Nephrectomy; Phosphorylation; Protein Biosynthesis; Protein Kinases; Ribosomal Protein S6 Kinases; Tetradecanoylphorbol Acetate | 1992 |
Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; DNA Replication; Gene Expression; Hyperplasia; Hypertrophy; In Vitro Techniques; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1992 |
Cardiac and renal hypertrophy is independent of tissue angiotensin converting enzyme and circulating angiotensin II in hypertensive rats.
Topics: Angiotensin II; Animals; Cardiomegaly; Desoxycorticosterone; Hypertension; Hypertension, Renovascular; Hypertrophy; Kidney; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Sodium Chloride | 1991 |
[Sar1]angiotensin II receptor-mediated stimulation of protein synthesis in chick heart cells.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; DNA; Hypertrophy; Muscle Proteins; Myocardium; Phenylephrine; Receptors, Angiotensin; RNA; Time Factors | 1990 |
Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells.
Topics: Amiloride; Angiotensin II; Animals; Cell Division; Cell Separation; Cells, Cultured; DNA; Flow Cytometry; Hypertrophy; Kidney Tubules, Proximal; Leucine; Mice; Nucleic Acid Hybridization; Oncogenes; Proteins; Receptors, Angiotensin; RNA | 1990 |
Possible role of the vascular renin-angiotensin system in hypertension and vascular hypertrophy.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta, Abdominal; Hypertension, Renovascular; Hypertrophy; Male; Rats; Rats, Inbred Strains; Renin-Angiotensin System; RNA, Messenger; Veins | 1992 |
Angiotensin II-1 receptors mediate both vasoconstrictor and hypertrophic responses in rat aortic smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Biphenyl Compounds; Cells, Cultured; DNA; Fluorescent Dyes; Fura-2; Hypertrophy; Imidazoles; Losartan; Male; Muscle Proteins; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1991 |
The influence of glucose concentration on angiotensin II-induced hypertrophy of proximal tubular cells in culture.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Line; Cyclic AMP; Glucose; Hypertrophy; Imidazoles; Kidney Tubules, Proximal; Losartan; Receptors, Angiotensin; Tetrazoles | 1991 |
Glomerular hypertrophy accelerates hypertensive glomerular injury in rats.
Topics: Albuminuria; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rate; Glomerulonephritis; Hypertension, Renal; Hypertrophy; Kidney Glomerulus; Male; Nephrectomy; Rats; Rats, Inbred Strains; Reference Values; Renal Circulation; Time Factors | 1991 |
Increased Ca2+ signaling after alpha-adrenoceptor activation in vascular hypertrophy.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Coarctation; Calcium; Fura-2; Hypertension; Hypertrophy; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred Strains; Signal Transduction | 1991 |
Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Hypertrophy; Infusion Pumps; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains; Renin; Splanchnic Circulation; Systole | 1991 |
Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Cell Division; Cell Line; Cyclic GMP; Down-Regulation; Hypertrophy; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Transforming Growth Factor beta | 1990 |
Differential regulation of Na+/H+ antiporter gene expression in vascular smooth muscle cells by hypertrophic and hyperplastic stimuli.
Topics: Angiotensin II; Animals; Blood; Carrier Proteins; Cell Division; Fibroblast Growth Factors; Gene Expression Regulation; Hyperplasia; Hypertrophy; Kinetics; Male; Mitogens; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protons; Rats; Rats, Inbred Strains; RNA, Messenger; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Hypertrophy and hyperplasia cause differing effects on vascular smooth muscle cell Na+/H+ exchange and intracellular pH.
Topics: Amiloride; Angiotensin II; Animals; Aorta, Thoracic; Blood; Cell Division; Hydrogen-Ion Concentration; Hyperplasia; Hypertrophy; Kinetics; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Kinase C; Protons; Rats; Rats, Inbred Strains; Sodium | 1990 |
Vascular hypertrophy, renin and blood pressure in the young spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Hypertension; Hypertrophy; Male; Mesenteric Arteries; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 1990 |
Ultrastructural juxtaglomerular cell changes in normotensive rats treated with quinapril, an inhibitor of angiotensin-converting enzyme.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Hyperplasia; Hypertrophy; Isoquinolines; Juxtaglomerular Apparatus; Quinapril; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines | 1990 |
Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; DNA; Hypertrophy; Male; Muscle, Smooth, Vascular; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Inbred Strains; RNA; Stimulation, Chemical; Time Factors | 1989 |
Arginine vasopressin-induced hypertrophy of cultured rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Cell Cycle; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Drug Synergism; Hypertrophy; Muscle Proteins; Muscle, Smooth, Vascular; Rats | 1989 |
[Pathogenesis of Bartter's disease].
Topics: Angiotensin II; Atrial Natriuretic Factor; Bartter Syndrome; Humans; Hyperaldosteronism; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kallikreins; Kidney Tubules; Kinins; Prostaglandins | 1988 |
Vascular hypertrophy and hypertension: a role for growth factors?
Topics: Angiotensin II; Animals; Blood Vessels; Feedback; Growth Substances; Hypertension; Hypertrophy; Male; Rats; Rats, Inbred Strains | 1988 |
Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Cell Division; Cells, Cultured; Cytological Techniques; Hypertrophy; Membrane Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Rats; Receptors, Angiotensin | 1988 |
Long-term trophic effect of sodium restriction on the rat adrenal zona glomerulosa. I. Its partial independence of the renin-angiotensin system.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Captopril; Diet, Sodium-Restricted; Endoplasmic Reticulum; Golgi Apparatus; Hypertrophy; Mitochondria; Potassium; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sodium | 1988 |
Long-term trophic effect of sodium restriction on the rat adrenal zona glomerulosa. II. The possible involvement of the inhibition of the dopaminergic system.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Bromocriptine; Captopril; Diet, Sodium-Restricted; Dopamine; Endoplasmic Reticulum; Hypertrophy; Metoclopramide; Mitochondria; Potassium; Rats; Rats, Inbred Strains; Sodium | 1988 |
Long-term stimulatory effect of neuropeptide-Y on the growth and steroidogenic capacity of rat adrenal zona glomerulosa.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Animals; Corticosterone; Hypertrophy; Male; Neuropeptide Y; Rats; Rats, Inbred Strains; Reference Values | 1988 |
[A trial diagnosis of latent dilated cardiomyopathy].
Topics: Angiotensin II; Cardiomyopathy, Dilated; Echocardiography; Evaluation Studies as Topic; Exercise Test; Fibrosis; Humans; Hypertrophy; Myocardium | 1987 |
A case of Bartter's syndrome with abnormal renin response to salt load.
Topics: Adrenal Gland Diseases; Aldosterone; Alkalosis; Angiotensin II; Blood Pressure; Child; Diet; Dwarfism; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Norepinephrine; Potassium; Renin; Sodium Chloride | 1969 |
Plasma renin in Bartter's syndrome: response of depression of stimuli for renin release.
Topics: Adrenal Gland Diseases; Alkalosis; Angiotensin II; Child; Growth Disorders; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Renin | 1969 |
[Study on the renin-angiotensin-aldosterone system. Evaluation of the dynamics of renal renin and adrenal cortex aldosterone production in the chronic stage of Goldblatt's rats].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Chromatography, Thin Layer; Chronic Disease; Histocytochemistry; Hypertension, Renal; Hypertrophy; Kidney; Male; Microscopy, Electron; Rats; Renal Artery; Renin | 1967 |
[Bartter's syndrome--case report and literature review].
Topics: Adrenal Gland Diseases; Adult; Alkalosis; Angiotensin II; Blood Pressure; Familial Mediterranean Fever; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney; Male; Paralysis; Renin; Tetany | 1969 |
A sibship with Bartter's syndrome: failure of total adrenalectomy to correct the potassium wasting.
Topics: Adrenal Gland Diseases; Adrenalectomy; Aldosterone; Alkalosis; Angiotensin II; Child, Preschool; Erythrocytes; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Hyponatremia; Infant; Juxtaglomerular Apparatus; Kidney; Male; Potassium; Renin; Sodium | 1969 |
Pathogenesis of Bartter's syndrome.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Albumins; Aldosterone; Alkalosis; Angiotensin II; Aniline Compounds; Anticonvulsants; Child; Dexamethasone; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney; Norepinephrine; Potassium; Potassium Chloride; Pyridones; Renin; Secretory Rate; Sodium; Spironolactone | 1969 |
So-called Bartter's syndrome.
Topics: Adrenal Gland Diseases; Albumins; Alkalosis; Angiotensin II; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Juxtaglomerular Apparatus; Renin; Sodium | 1969 |
Bartter's syndrome. A report of four cases, including three in one sibship, with comparative histologic evaluation of the juxtaglomerular apparatuses and glomeruli.
Topics: Alkalosis; Angiotensin II; Blood Pressure; Carbon Dioxide; Cerebrospinal Fluid Proteins; Electrolytes; Female; Glycosuria; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Infant; Infant, Newborn; Juxtaglomerular Apparatus; Kidney Diseases; Kidney Glomerulus; Magnesium; Male; Microscopy; Microscopy, Electron; Phosphorus; Proteinuria; Specific Gravity; Spironolactone | 1970 |
An unusual type of hypokalaemic alkalosis with a disturbance of renin and aldosterone.
Topics: Adolescent; Adrenal Cortex Hormones; Albumins; Aldosterone; Alkalosis; Angiotensin II; Creatinine; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Kidney Diseases; Male; Potassium; Renin; Spironolactone; Triamterene | 1970 |
Case studies of siblings with juxtaglomerular hyperplasia and secondary aldosteronism associated with severe azotemia and renal rickets--Bartter's syndrome or disease?
Topics: Aldosterone; Alkalosis; Angiotensin II; Bone Diseases; Child; Child, Preschool; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Kidney Glomerulus; Male; Spironolactone; Triamterene; Valine | 1970 |
[Permanent hypertension and changes in the sodium-potassium content of the aortic wall following angiotensin II infusions in rats].
Topics: Adrenal Glands; Adrenocortical Hyperfunction; Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension, Renal; Hypertrophy; Organ Size; Potassium; Rats; Sodium | 1970 |
A case of Bartter's syndrome with surgical treatment followed for four years.
Topics: Adrenalectomy; Adult; Alkalosis; Angiotensin II; Epinephrine; Follow-Up Studies; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Male; Renin | 1971 |
[Angiotensin resistence and hyperaldosteronism with normal blood pressure].
Topics: Adult; Alkalosis; Angiotensin II; Blood Pressure; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases | 1967 |
Bartter's syndrome. A manifestation of renal tubular defects.
Topics: Adult; Aldosterone; Alkalosis; Angiotensin II; Bicarbonates; Chlorides; Diet Therapy; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Male; Potassium; Renin; Sodium; Sodium Chloride | 1972 |
[Angiotensin resistance. Critical remarks on the so called Bartter syndrome].
Topics: Adult; Aged; Alkalosis; Angiotensin II; Blood Pressure; Blood Pressure Determination; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Norepinephrine; Photometry; Potassium; Potassium Chloride | 1971 |
[The Bartter syndrome and the pseudo-Bartter syndrome].
Topics: Adult; Alkalosis; Angiotensin II; Biopsy; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Male; Middle Aged; Renin; Sodium Chloride; Syndrome | 1972 |
A study of the inhibition of the renin-angiotensin system in renal potassium wasting syndromes, including Bartter's syndrome.
Topics: Adolescent; Alkalosis; Angiotensin II; Calcium; Child; Child, Preschool; Cystinosis; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Hypophosphatemia, Familial; Juxtaglomerular Apparatus; Kidney Diseases; Male; Potassium; Proteinuria; Renin; Syndrome | 1972 |
Studies on the site of renal salt loss in a patient with Bartter's syndrome.
Topics: Adolescent; Adult; Alkalosis; Angiotensin II; Biological Transport, Active; Blood Pressure; Child; Child, Preschool; Chlorothiazide; Glomerular Filtration Rate; Growth Disorders; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Inulin; Juxtaglomerular Apparatus; Kidney Diseases; Kidney Function Tests; Kidney Tubules, Distal; Loop of Henle; Male; Natriuresis; Sodium; Syndrome | 1973 |
Six year follow-up of a child with Bartter syndrome.
Topics: Aldosterone; Alkalosis; Angiotensin II; Biopsy; Blood Pressure; Child, Preschool; Diet Therapy; Female; Follow-Up Studies; Growth Disorders; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Concentrating Ability; Kidney Diseases; Norepinephrine; Potassium; Renin; Secretory Rate; Sodium Chloride; Spironolactone; Syndrome; Vasopressins | 1973 |
Some observations on the pathogenesis of Bartter's syndrome.
Topics: Adult; Aldosterone; Alkalosis; Angiotensin II; Blood Volume; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney; Kidney Diseases; Male; Potassium; Propranolol; Renin; Spironolactone | 1973 |
Bartter's syndrome and erythrocytosis.
Topics: Adult; Alkalosis; Angiotensin II; Blood Cell Count; Blood Pressure; Erythrocytes; Erythropoiesis; Hematocrit; Hemoglobinometry; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Iron; Juxtaglomerular Apparatus; Kidney Diseases; Male; Polycythemia; Potassium; Renin; Reticulocytes; Sodium; Syndrome | 1973 |