angiotensin ii has been researched along with Hypertension in 6391 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2142 (33.52) | 18.7374 |
| 1990's | 1194 (18.68) | 18.2507 |
| 2000's | 1301 (20.36) | 29.6817 |
| 2010's | 1320 (20.65) | 24.3611 |
| 2020's | 434 (6.79) | 2.80 |
| Authors | Studies |
|---|---|
| Alajarín, R; Alvarez-Builla, J; Díez-Marqués, ML; García, G; Griera, M; Rodríguez-Puyol, D; Rodríguez-Puyol, M; Sánchez-Alonso, P; Serrano, I; Vaquero, JJ | 2 |
| De, A; Pande, V; Sinha, A; Tiwari, A | 1 |
| Beltz, TG; Felder, RB; Guo, F; Kim Johnson, A; Wei, SG; Xue, B; Yu, Y | 1 |
| Ali, F; Cheng, Y; Chu, J; Fang, Y; Liu, H; Peng, J; Shen, A; Wang, D; Wei, L; Wu, M; Xie, Q; Yan, M; Yang, Y | 1 |
| Garcia Fragas, M; Gastão Davanzo, G | 1 |
| Billoff, S; Bode-Böger, SM; Bornstein, SR; Deussen, A; Jarzebska, N; Kolouschek, A; Kopaliani, I; Mangoni, AA; Martens-Lobenhoffer, J; Ragavan, VN; Rodionov, RN; Weiss, N | 1 |
| Ao, M; Barbaro, NR; de la Visitacion, N; Harrison, DG; Loperena, R; Patrick, DM; Shibao, CA; Smart, CD; Van Beusecum, JP; Xiao, L; Zhao, S | 1 |
| Carnevale, D; Carnevale, L; Iodice, D; Lembo, G; Migliaccio, A; Pallante, F; Perrotta, M; Perrotta, S | 1 |
| Cho, SN; Choi, JA; Choi, SY; Lee, J; Lee, SA; Nguyen, TD; Son, SH; Song, CH | 1 |
| Frąk, W; Franczyk, B; Kućmierz, J; Młynarska, E; Rysz, J | 1 |
| Chen, X; Ji, J; Li, C; Li, Y; Lin, L; Xu, R; Zhang, L | 1 |
| Behuliak, M; Hojná, S; Rauchová, H; Řezáčová, L; Valovič, P; Vaněčková, I; Vavřínová, A; Zicha, J | 1 |
| Bonventre, JV; Dutta, SR; Gonzalez, FJ; Lew, J; Malik, KU; Motiwala, M; Shin, JS; Singh, P; Song, CY | 1 |
| Chang, YM; Chen, RJ; Chiu, PL; Day, CH; Huang, CY; Huang, HY; Kuo, WW; Liang-Yo, Y; Lin, HJ; Mahendran, R; Padma, VV | 1 |
| Cao, D; Chang, YZ; Du, R; Gao, F; Gao, X; Jin, X; Li, H; Li, J; Li, Y; Ling, S; Liu, C; Liu, S; Liu, Z; Song, J; Sun, W; Tan, Y; Wang, Y; Xing, W; Yang, X; Yuan, M; Zhao, D; Zhao, Y; Zhong, G | 1 |
| Azushima, K; Kinguchi, S; Tamura, K; Wakui, H; Yamaji, T | 1 |
| Becares, M; Bermeo, H; Briones, AM; García-Redondo, AB; González-Amor, M; Guerra, S; Jorge, I; Martínez-González, J; Montezano, AC; Redondo, JM; Rios, FJ; Rodrigues-Díez, R; Rodríguez, C; Ruiz-Rodríguez, MJ; Salaices, M; Touyz, RM; Vázquez, J; Zalba, G | 1 |
| Brines, M; Chavan, SS; Li, JH; Shah, V; Stiegler, A; Tamari, Y; Tracey, KJ; Tsaava, T; Tynan, A; Yang, H | 1 |
| Chen, C; Gao, Z; Meng, Y; Wang, L; Zhang, X; Zheng, C; Zheng, Y | 1 |
| Akdeniz, YS; Biberoğlu, S; Bolayırlı, İM; Börekçi, Ş; Çakmak, F; İkizceli, İ; İpekci, A; Kanbakan, A; Konukoğlu, D; Özkan, S; Ürkmez, S | 1 |
| Li, X; Liang, Y; Wu, Y; Xiao, Y; Xie, P; Zhong, Y | 1 |
| Masoumi-Ardakani, Y; Najafipour, H; Rostamzadeh, F; Yeganeh-Hajahmadi, M | 1 |
| Cai, X; Deng, L; Fan, G; Guo, R; Li, L; Liu, W; Ni, J; Xu, Q; Zhang, D; Zhao, Y | 1 |
| Kim, HS; Kim, HY | 2 |
| Dai, YF; Li, J; Pan, YJ; Qin, F; Zhong, XG | 1 |
| Ramchandra, R; Shanks, J | 1 |
| Baiza-Gutman, LA; Bautista-Pérez, R; Castro-Moreno, P; Escobar-Sánchez, ML; Ibarra-Barajas, M; Mondragón-Huerta, CG; Salas-Garrido, CG; Valle-Mondragón, LD | 1 |
| Cipolla, MJ; Li, Z | 1 |
| Chen, X; Li, G; Liu, J; Yang, H | 1 |
| Biernat-Kałuża, E; Dobrowolski, P; Guzik, B; Guzik, TJ; Imiela, AM; Januszewicz, A; Januszewicz, M; Konior-Rozlachowska, A; Mikołajczyk, TP; Prejbisz, A; Siedliński, M; Wróbel, A | 1 |
| Jala, VR; Juin, SK; Majumder, S; Pushpakumar, S; Sen, U | 1 |
| Kuruppu, S; Rajapakse, NW; Tran, S | 1 |
| Chakraborty, K; Paulose, SK | 1 |
| Ahmad, S; Ferrario, CM; Figueroa, JP; Groban, L; Meredith, JW; Saha, A; VonCannon, JL; Wright, KN; Zhang, J | 1 |
| Carletti, R; Castoldi, G; di Gioia, CRT; Ippolito, S; Pelucchi, S; Stella, A; Zatti, G; Zerbini, G | 1 |
| Alexander, BT; Dalmasso, C; Ojeda, NB; Reckelhoff, JF; Shawky, NM; Stachenfeld, N; Zuchowski, Y | 1 |
| Liu, Y; Pan, N; Wang, G; Wang, R; Yang, H; Yu, Y; Yuan, F; Zhang, B; Zhao, L | 1 |
| Chopada, K; Hati, S; Sakure, A; Shukla, P | 1 |
| Glass, MJ; Johnson, MA; Milner, TA; Wang, G; Woods, C | 1 |
| Fan, T; Feng, X; Gao, R; Ge, W; Guo, W; Hou, Y; Song, X; Wang, J | 1 |
| Cheng, Y; Chu, J; Lin, S; Lu, Z; Peng, J; Shen, A; Shen, Z; Wang, T; Wang, Y; Xie, L | 1 |
| Chen, D; Cheng, Y; Gong, Y; Han, W; Liu, Z; Song, B; Zhang, R; Zhang, Z | 1 |
| Cui, JL; Du, HB; Johnson, AK; Sun, S; Wu, GB; Wu, JL; Xue, B; Zhai, JY; Zhang, GS; Zhang, Y; Zhao, ZA; Zhao, ZG | 1 |
| Al-Hasani, J; Friede, PAP; Ghosh, S; Hecker, M; Nahar, T; Reil, JC; Sens-Albert, C; Trogisch, FA | 1 |
| Ali, BH; Beegam, S; Elzaki, O; Ferdous, Z; Greish, YE; Nemmar, A; Tariq, S; Zaaba, NE | 1 |
| Chen, Y; Dong, Z; Li, X; Liu, X; Liu, Y; Shi, H; Song, J; Tang, J; Xie, M; Zhang, M; Zhang, Z; Zhong, J | 1 |
| Fung, K; Graham, L; Jing, B; Lee, SJ; Li, Y; Marcum, ZA; Odden, MC; Peralta, CA; Steinman, MA | 1 |
| Chen, H; Qiao, H; Wei, F; Zhao, Q | 1 |
| Axelsen, LN; Goetze, JP; Holstein-Rathlou, NH; Jensen, LJ; Jonassen, TE; Lund, MAV; Salomonsson, M; Sørensen, CM | 1 |
| Gonzalez, AA; Hennrikus, MT; Lara, LS; Prieto, MC | 1 |
| Chen, Y; Dong, Z; Guo, Y; Jin, H; Li, X; Liu, X; Liu, Y; Song, J; Wang, N; Xu, Y; Zhang, M; Zhang, Z; Zhong, J | 1 |
| Afanasiev, SA; Blanco, P; Burger, D; Burns, KD; Correa, JWN; Gutsol, AA; Hale, TM; Hébert, RL; Holterman, CE; Kennedy, CRJ; Nasrallah, R; Thibodeau, JF; Touyz, RM | 1 |
| Chen, X; Gao, H; Li, F; Sun, Q; Wang, J; Wu, H; Xu, J; Yang, R; Yuan, S | 1 |
| Bai, L; Chen, Y; Gao, J; Guo, X; Lai, B; Shang, F; Wang, C; Wen, E | 1 |
| Stanley, JC | 1 |
| Deng, Y; Lei, J; Li, H; Li, X; Peng, L; Tuo, B; Xu, J; Zhang, W; Zou, Q | 1 |
| Geng, Z; Xiong, XQ; Ye, C; Zhang, LL; Zheng, F; Zhou, YB; Zhu, GQ | 1 |
| Brandes, RP; Pliquett, RU | 1 |
| Calus, E; De Deyn, PP; De Meyer, GRY; Hendrickx, JO; Van Dam, D | 1 |
| Ali, Y; Dohi, K; Ito, H; Ito, M; Katayama, K; Okamoto, R; Zhe, Y | 1 |
| Chen, GH; Chen, JT; Ge, YJ; He, S; Kong, XY; Li, XY; Yang, S; Zhang, P | 1 |
| Li, Y; Zhang, J; Zhang, S; Zou, F | 1 |
| Brozoski, DT; Fang, S; Kumar, G; Lin, CW; Lu, KT; Mathison, AJ; Muskus Veitia, PC; Quelle, FW; Reho, JJ; Sigmund, CD; Silva, SD; Teng, BQ; Wackman, KK; Werthman, AM; Wu, J | 1 |
| Chrissobolis, S; D'Souza, MS; Guisinger, TC; Luu, AN; Seeley, SL; Waldschmidt, RA | 1 |
| Ceroni, A; Manica, LA; Michelini, LC; Raquel, HA | 1 |
| Asada, Y; Chosa, E; Funamoto, T; Hatakeyama, K; Kato, J; Kitamura, K; Koide, M; Nakamichi, Y; Otsu, M; Sekita-Hatakeyama, Y; Tsuruda, T; Udagawa, N; Yamashita, A | 1 |
| Crowley, SD; Griffiths, R; Ide, S; Lu, X; Ren, J; Rudemiller, NP; Souma, T; Wen, Y; Zhang, J | 1 |
| Assa, C; Barrera, V; Bhetariya, P; Chen, J; Cheng, HS; Feinberg, MW; Jamaiyar, A; Khyrul Wara, A; Liu, Z; Mitchell, RN; Pandey, AK; Pérez-Cremades, D; Plutzky, J; Tzani, A; Zhang, B; Zhuang, R | 1 |
| Cantrell, AC; Chen, JX; He, X; Williams, QA; Zeng, H | 1 |
| Chen, H; Cheng, L; Maboh, RN; Mao, GW; Wang, H; Wu, XY | 1 |
| Ji, Y; Kong, X; Li, L; Lu, Y; Qiu, M; Shen, Y; Shu, H; Sun, W; Tian, Y | 1 |
| A Alattar, R; A Elrayess, M; A Hssain, A; Abdelmajid, A; Abusriwil, H; Al Samawi, M; Al Suwaidi, J; Al-Maslamani, M; Al-Ruweidi, MKAA; Alhariri, B; Almuraikhy, S; Nair, A; Omar Saad, M; Omrani, AS; Parengal, J; T Zedan, H; Yalcin, HC; Yassine, HM | 1 |
| Gan, L; Hu, X; Li, H; Li, X; Lu, Y; Meng, T; Peng, L; Tang, R; Wang, W; Xiao, C; Xiao, P; Zhou, Q | 1 |
| Li, D; Liu, Q; Xie, Y; Yan, J | 1 |
| Enggaard, C; Hansen, PBL; Jensen, BL; Palarasah, Y; Stubbe, J; Svenningsen, P; Thangaraj, SS | 1 |
| Boyd, JH; Burns, K; Cheng, MP; Donohoe, K; Du, B; Fowler, R; Goodlett, D; Haljan, G; Hernandez, G; Lamontagne, F; Lee, T; Lee, TC; Mann, P; Marshall, J; Maslove, D; McGeer, A; Mohammed, Y; Murthy, S; Patrick, DM; Patrigeon, SP; Peng, Z; Rocheleau, GLY; Russell, JA; Singer, J; Slutsky, AS; Sweet, D; Tran, K; Vinh, DC; Walley, KR; Winston, BW | 1 |
| Cheng, Z; Li, X; Liu, Q; Luo, M; Luo, S; Lv, D; Shang, F; Wang, R; Xia, Y; Yan, J; Zhang, Z | 1 |
| D'Addiaro, C; De Miguel, C; Gupte, R; Gupte, SA; Matsumura, S; Miano, JM; Slivano, OJ; Stier, C | 1 |
| Lampa, E; Loader, J; Sundström, J; Taylor, FC | 1 |
| Bai, F; Banks, TE; Rajapaksha, M; Wang, NP; Zhang, LH; Zhao, ZQ | 1 |
| Han, X; Li, G; Liang, G; Liang, S; Long, X; Luo, W; Sun, J; Wang, M; Yu, T; Zhang, Y | 1 |
| Brizzio, A; Cela, EM; Corradi, GR; Espeche, WG; Gironacci, MM; Gonzales Maglio, DH; Nuñez, M; Pérez Duhalde, JI; Salazar, MR; Silva, MG | 1 |
| Azizi, M; Babaahmadi-Rezaei, H; Beheshti-Nasab, H; Ghaderi-Zefrehi, H; Mehta, JL; Rezaei, M | 1 |
| Faraci, FM; Kinzenbaw, DA; Langmack, L | 1 |
| Li, ML; Ren, CZ; Tan, X; Wang, W; Wang, WZ; Wang, YK; Wu, ZT; Yang, YH | 1 |
| Chen, C; Hu, Y; Huang, J; Jose, PA; Lei, L; Li, Z; Ren, H; Si, L; Su, Q; Wang, W; Yan, H; Yang, J; Zeng, C; Zhang, F; Zheng, S | 1 |
| Han, W; Qu, X; Wang, M; Ye, M; Zhang, S | 1 |
| Lu, YW; Xie, YY; Yu, GR | 1 |
| Baskaran, R; Chen, RJ; Day, CH; Ho, TJ; Huang, CY; Kuo, WW; Lin, JY; Lin, MY; Lin, YM; Padma, VV | 1 |
| Baglieri, C; Capelli, C; Casolo, A; Conti, E; Gattoni, C; Girardi, M; Jurkiewicz, A; Jurkiewicz, NH; Musial, DC; Nuccio, S; Rocha, K; Souza Bomfim, GH | 1 |
| Deng, H; Li, M; Li, Y; Li, Z; Liu, J; Shen, J; Xie, X | 1 |
| Corballis, N; Tsampasian, V; Vassiliou, VS | 1 |
| Alharbi, HO; Barrington, C; Cameron, AJM; Chotani, S; Clerk, A; Cook, AC; Cooper, STE; Cull, JJ; Herbert, E; Marshall, JJT; Meijles, DN; Mohun, T; Parker, PJ; Priestnall, SL; Prin, F; Rackham, OJL; Siow, B; Snoeks, T; Stuckey, DJ; Suáarez-Bonnet, A; Vanyai, H; Zaw Thin, M | 1 |
| Cai, Z; He, B; Li, Y; Shen, L; Sun, Z; Wang, X; Xiao, Q; Xu, K; Xu, L; Yang, W; Yang, X; Yin, A; Yuan, R; Zhang, W; Zhou, B; Zhuang, F | 1 |
| Choopani, S; Nematbakhsh, M | 1 |
| Chen, L; Guan, X; Khan, ZA; Li, X; Liang, G; Luo, W; Qian, J; Wang, Y; Xu, Z; Yang, D; Zhuang, Z | 1 |
| Chiong, M; Hernandez-Fuentes, C; Lavandero, S; Lopez-Crisosto, C; Martinez-Bilbao, J; Norambuena-Soto, I; Parra, V | 1 |
| Danser, AHJ; Daugherty, A; Foster, D; Garrelds, IM; Hoorn, EJ; Lu, HS; Mirabito Colafella, KM; Nioi, P; Ren, L; Uijl, E; van Veghel, R; Ye, D | 1 |
| Dugas, CM; Franco, M; Katsurada, A; Navar, LG; Satou, R | 1 |
| Cooper, STE; Haines, ZHR; Malone, GO; Meijles, DN; Sheppard, MN; Westaby, JD | 1 |
| Chang, WT; Chen, CL; Chen, ZC; Chu, JS; Huang, TL; Lin, YW; Liu, PY; Shih, JY | 1 |
| Abo Laban, AI; El-Bassossy, HM; Hassan, NA | 1 |
| Kim, CW; Kim, I; Lee, S; Young Kim, J | 1 |
| Cao, S; Wang, Z; Xing, L; Zhang, W; Zhou, L | 1 |
| Algara-Suarez, P; Amissi, S; Auger, C; Belcastro, E; Bruckert, C; Chaker, AB; Houngue, U; Jesel, L; Matsushita, K; Morel, O; Mroueh, A; Ohlmann, P; Park, SH; Remila, L; Schini-Kerth, VB | 1 |
| Agbaraolorunpo, F; Anigbogu, CN; Ogunnowo, SA; Oloyo, AK; Sofola, O | 1 |
| An, J; Dong, L; Gao, F; Li, G; Li, J; Li, Y; Wang, L; Wang, X; Xing, W; Xu, K; Yang, H; Zhang, X; Zhou, J | 1 |
| Han, P; Jensen, DM; Kriegel, AJ; Liang, M; Liu, J; Lopez-Berestein, G; Mangala, LS; Sood, AK; Usa, K; Widlansky, ME | 1 |
| Byeon, S; Choi, SK; Haam, CE; Kwon, Y; Lee, YH | 1 |
| Barris, CT; Belin de Chantemèle, EJ; Faulkner, JL | 1 |
| Li, G; Liang, G; Liang, S; Luo, W; Sun, J; Wang, M; Yu, T; Zou, C | 1 |
| Hu, G; Huang, D; Li, G; Li, N; Li, PL; Ritter, JK; Yuan, X; Zou, Y | 1 |
| Ahıshalı, B; Akcan, U; Altunsu, D; Atis, M; Ayvaz, E; Girouard, H; Kaya, M; Sarıkaya, D; Temizyürek, A; Uğur Yılmaz, C | 1 |
| Han, C; Hu, L; Huang, R; Huang, Y; Li, J; Lin, H; Ooi, K; Qian, X; Ren, X; Xia, C; Zhang, S | 1 |
| Chen, D; Chen, K; Chu, J; Gao, H; Jia, P; Lin, S; Lin, W; Long, L; Peng, J; Shen, A; Wang, T; Zhu, Y; Zhu, Z | 1 |
| Chang, YC; Chen, RJ; Hong, WZ; Huang, CY; Kuo, CH; Kuo, WW; Lu, SY; Mhone, TG; Tsai, BC | 1 |
| Chai, CS; Goh, SL; Lim, LL; Lim, QH; Loh, HH; Sukor, N; Yee, A | 1 |
| Clahsen-van Groningen, MC; Cruz-López, EO; Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Kasper, A; Nioi, P; Poglitsch, M; Ren, L; Rooney, T; Uijl, E; van Veghel, R; Zlatev, I | 1 |
| Hu, X; Huang, W; Khan, ZA; Liang, G; Lin, K; Luo, W; Su, L; Wang, Y; Wu, G; Yang, N; Zhou, H | 1 |
| Acet, HA; Ateş, B; Özhan, O; Parlakpinar, H; Tanrıverdi, LH; Ulu, A; Vardı, N; Yıldız, A | 1 |
| Buller, S; Cooper, SG; Feng Earley, Y; Gayban, AJB; Satou, R; Souza, LAC; Worker, CJ | 1 |
| Aileru, A; Byrum, R; Diz, D; Peele, K; Swami Vetha, BS | 1 |
| Contoreggi, NH; Glass, MJ; Johnson, MA; Milner, TA; Wang, G; Woods, C | 1 |
| Bai, C; Chen, J; Hui, R; Li, H; Lin, Y; Liu, J; Ping, J; Song, L; Su, M; Sun, Y; Wen, H; Xiao, N; Xu, H; Zhang, M; Zhang, Y | 1 |
| Liang, G; Luo, W; Shan, P; Wang, M; Wang, Y; Wu, G; Xu, D; Yang, N; Zou, C | 1 |
| Akbari, A; Gao, J; Wang, T | 1 |
| Ichinose, M; Iguchi, Y; Ikeda, K; Inaoka, N; Iriyama, T; Katoh, Y; Kotajima-Murakami, H; Kumasawa, K; Nagamatsu, T; Osuga, Y; Sakuma, H; Sato, A; Sayama, S; Seyama, T; Sone, K; Toshimitsu, M; Yano, E; Yoshikawa, M | 1 |
| Chen, W; Du, H; Lai, Y; Li, Y; Liu, G; Liu, H; Woo, K; Xu, Y; Yin, Y; Zhang, B; Zhou, H | 1 |
| Červenka, L; Gawrys, O; Jíchová, Š; Kala, P; Kompanowska-Jezierska, E; Maxová, H; Miklovič, M; Sadowski, J; Škaroupková, P; Táborský, M; Vaněčková, I; Vaňourková, Z; Veselka, J; Walkowska, A | 1 |
| Chen, RX; Contoreggi, NH; Glass, MJ; Johnson, MA; Marongiu, R; Marques-Lopes, J; Mazid, S; Milner, TA; Rubin, BR; Welington, D | 1 |
| Dang, Q; Han, C; Li, M; Li, P; Li, Y; Li, Z; Yang, Y | 1 |
| Baumbach, GL; Chapleau, MW; Faraci, FM; Gerhold, TD; Sabharwal, R | 1 |
| Lee, SK; Ling, WC; Mohd Sabri, NA; Murugan, DD | 1 |
| Ahmad, S; Ferrario, CM; Meredith, WJ; Saha, A; VonCannon, JL | 1 |
| Adesuyan, M; Alsugeir, D; Brauer, R; Cheung, ECL; Chui, CSL; Howard, R; Jani, YH; Wong, ICK | 1 |
| Chen, Y; Fu, Z; Kaewsaro, K; Lambert, J; Yang, T; Zheng, H | 1 |
| Chen, YH; Li, XT; Liang, LR; Liu, XY; Liu, Y; Miao, R; Song, JW; Zhang, MW; Zhang, ZZ; Zhong, JC | 1 |
| Briones, AM; Dalli, J; de Benito-Bueno, A; Díaz Del Campo, LS; Duro-Sánchez, S; García-Redondo, AB; Palmas, F; Peraza, DA; Rodrigues-Díez, R; Rodríguez, C; Salaices, M; Socuéllamos, PG; Valenzuela, C; Zaragoza, C | 1 |
| Fang, Z; Li, H; Li, J; Li, Y; Ma, S; Wang, Y; Xu, J; Zheng, Y | 1 |
| Dogar, A; Meister, TA; Messerli, FH; Paoloni-Giacobino, A; Rexhaj, E; Sartori, C; Scherrer, U; Soria, R; Stenz, L | 1 |
| Atchison, DK; Bergin, IL; Bitzer, M; Converso-Baran, K; Ganesh, SK; Hartman, JR; Ju, W; O'Connor, CL; Smrcka, AV; Wang, Y; Zhang, H | 1 |
| Bai, J; Li, HH; Lin, QY; Zhang, YL | 1 |
| Guo, CL; Li, B; Liu, HM; Lu, ZY | 1 |
| Behuliak, M; Řezáčová, L; Vaněčková, I; Zicha, J | 1 |
| Cicalese, S; Eguchi, S; Elliott, KJ; Hashimoto, T; Okuno, K; Rizzo, V; Torimoto, K | 1 |
| Bai, XJ; Kang, YM; Liu, XJ; Qiao, JA; Su, YK; Sun, YJ; Yang, HY; Yang, ZM; Yin, LX; Yu, XJ; Zhang, N | 1 |
| Abdulla, MH; AlMarabeh, S; Barry, EF; Beshara, J; Johns, EJ; O'Neill, J; Parna-Gile, E | 1 |
| Chen, Y; Li, S; Shan, M; Shi, L; Zhang, Y; Zhou, Y | 1 |
| Dong, B; Liu, Z; Qiu, Y; Tao, J; Tu, Q; Xu, L; Zhang, H | 1 |
| Anand-Srivastava, MB; Li, Y | 2 |
| Ariza-Guzman, PA; Collister, JP; Osborn, JW; Ployngam, T | 1 |
| Coffman, TM; Emathinger, JM; Griffiths, RC; Gurley, SB; Hutchens, MP; Mattocks, NK; Nelson, JW; Ortiz-Melo, DI; Piehowski, PD; Prescott, J; Wakasaki, R; Xu, K | 1 |
| Bress, AP; Gabriel, N; Hernandez, I; Marcum, ZA | 1 |
| Cicalese, SM; Coffman, TM; Eguchi, S; Hashimoto, T; Okuno, K; Preston, K; Rizzo, V; Sparks, MA; Torimoto, K | 1 |
| Bai, RY; Deng, XL; Du, XJ; Han, MZ; Lai, BC; Pang, ZD; Sun, X; Wang, Y; Wu, W; Zhang, Y; Zhang, YJ | 1 |
| Hazama, A; Katsuda, SI | 1 |
| Chatterjee, B; Fadnavis, M; Kuber, B | 1 |
| Asada, Y; Jiang, D; Kaikita, K; Kato, J; Kawagoe, Y; Kitamura, K; Matsuzaki, M; Tsuruda, T | 1 |
| Chen, X; Dai, W; Li, S; Liu, R; Ru, W; Sun, Y; Wang, C; Xie, X; Yang, S; Zhong, A; Zhong, L | 1 |
| Miura, SI | 1 |
| Chaigneau, M; Gilles, N; Iturrioz, X; Kessler, P; Llorens-Cortes, C; Robin, P; Servent, D; Van Baelen, AC | 1 |
| Nguyen, J; Vandemark, C; Zhao, ZQ | 1 |
| Fu, G; Gong, Y; Han, X; Huang, H; Huang, W; Liang, G; Long, X; Luo, W; Wang, Y; Wu, L; Ye, S; Ye, Y; Zhao, X | 1 |
| Alves, AJ; Bertoquini, S; de Melo, JB; Figueiredo, D; Garcia, C; Guimarães, GV; Leitão, C; Lopes, S; Mesquita-Bastos, J; Oliveira, J; Pescatello, LS; Polonia, J; Ribau, V; Ribeiro, F; Ribeiro, IP; Teixeira, M | 1 |
| Kopkan, L; Kratky, V; Sykora, M; Szeiffova Bacova, B; Tribulova, N | 1 |
| Girouard, H; Vallerand, D; Youwakim, J | 1 |
| Guo, X; Hong, J; Li, C; Li, Y; Mao, J; Tang, Y; Wang, Y; Xu, B; Yu, J; Zhou, M | 1 |
| Huang, Q; Tian, S; Wu, T; Zheng, Y | 1 |
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| Aquino, V; Kim, S; Lobaton, GO; Oliveira, AC; Pepine, CJ; Raizada, MK; Richards, EM; Sharma, RK; Sumners, C; Yang, T | 1 |
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| Graham, D; Guzik, TJ; Justo-Junior, AS; Kiss, AK; Kowalczyk, P; Koziol, J; Kusmierczyk, Z; Luc, K; Maffia, P; Mazur, M; Mikolajczyk, TP; Naruszewicz, M; Nosalski, R; Schramm-Luc, A; Skiba, DS | 1 |
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| Aguilar, MI; Alegría-Herrera, E; Avilés-Flores, M; Fuentes-Mata, M; Herrera-Ruiz, M; Jiménez-Ferrer, E; Román-Ramos, R; Santillán-Urquiza, MA; Zamilpa, A | 1 |
| Fujigaki, Y; Ishizawa, K; Li, J; Lifton, RP; Shibata, S; Tamura, Y; Uchida, S; Wang, Q; Yamazaki, O | 1 |
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| Bastacky, SI; Jackson, EK; Salah, E; Tofovic, SP | 1 |
| Becirovic-Agic, M; Ericsson, M; Hultström, M; Jönsson, S; Karlsen, TV; Leh, S; Lidén, Å; Nilsson, SK; Reed, RK; Skogstrand, T; Tveitarås, MK | 1 |
| Cunningham, JT; Cunningham, RL; Farmer, GE; Marciante, AB; Nedungadi, TP; Shell, B; Snyder, B; Wang, LA | 1 |
| Agbor, LN; Davis, DR; Fang, S; Guo, DF; Hu, C; Ibeawuchi, SC; Keen, HL; Liu, X; Lu, KT; Mukohda, M; Nair, AR; Quelle, FW; Sigmund, CD; Wu, J | 1 |
| Ahıshalı, B; Akcan, U; Arıcan, N; Atış, M; Deniz Ceylan, U; Düzgün, P; Karahüseyinoğlu, S; Kaya, M; Nur Şahin, G; Orhan, N; Uğur Yılmaz, C | 1 |
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| Ait-Aissa, K; Castañeda, D; Gabani, M; Grumbach, I; Irani, K; Jacobs, JS; Kassan, M; Kim, YR; Koval, O; Liu, J; Trebak, M; Vikram, A | 1 |
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| Ahmari, N; Baekey, DM; Denson, H; Geis, NM; Khoshbouei, H; Larkin, R; Miller, DR; Raizada, MK; Redler, T; Santisteban, MM; Zubcevic, J | 1 |
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| Bair, TB; Chapleau, MW; Dibbern, ME; Grumbach, IM; Ketsawatsomkron, P; Kutschke, WJ; Lamping, KG; Morgan, DA; Nuno, DW; Prasad, AM; Rahmouni, K; Sigmund, CD; Venema, AN; Weiss, RM | 1 |
| Choudhury, S; Gupta, P; Kandasamy, K; Kutty, HS; Mishra, SK; Sarath, TS; Sarkar, SN; Waghe, P | 1 |
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| Cismowski, MJ; Galantowicz, ML; Husarek, KE; Katz, PS; Lucchesi, PA; Trask, AJ | 1 |
| Bernstein, KE; Giani, JF; Gonzalez-Villalobos, RA; Han, J; Janjulia, T; McDonough, AA; Rodriguez-Iturbe, B; Shen, XZ; Toblli, JE | 1 |
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| Chen, W; Foss, JD; Harrison, DG; Itani, HA; Kirabo, A; Loperena, R; Mernaugh, RL; Osborn, JW; Roberts, J; Saleh, MA; Takahashi, T; Wang, F; Wu, J; Xiao, L; Zhu, L | 1 |
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| Devynck, MA; Macdonald, GJ; Matthews, PG; Meyer, P; Pernollet, MG; Raisman, RS | 1 |
| Boucher, R; Demassieux, S; Garcia, R; Genest, J; Gutkowska, J | 1 |
| Dluhy, RG; Hollenberg, NK; Moore, TJ; Swartz, SL; Williams, GH | 1 |
| Arabidze, GG; Novikova, LS | 1 |
| Jung, D | 1 |
| Kondo, K; Saruta, T | 1 |
| Gordon, DL; Rovner, DR; Swisher, SN | 1 |
| Brown, JJ; Fraser, R; Lever, AF; Mason, PA; Robertson, JI | 1 |
| Hubbard, JI; Sirett, NE; Thornton, SN | 1 |
| Case, DB; Laragh, JH; Wallace, JM | 1 |
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| Bumpus, FM; Khosla, MC; Page, IH | 1 |
| Shimada, K; Yazaki, Y | 1 |
| Lapshina, LA; Vlasenko, MA | 1 |
| Johnston, CI; Matthews, PG; McGrath, BP | 1 |
| Peart, WS | 1 |
| Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Kay, AW; Lever, AF; Owen, K; Peart, WS; Robertson, JI | 1 |
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| Abrams, HL; Adams, DF; Burger, BM; Chenitz, WR; Hollenberg, NK; Merrill, JP; Solomon, H | 1 |
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| Burkhalter, JF; Marks, L; Maxwell, MH; Varady, P; Waks, U; Zawada, ET | 1 |
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| Cordes, U; Distler, A; Philipp, T; Wolff, HP | 1 |
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| Peach, MJ; Vaughan, ED | 1 |
| Keeton, TK; Mitchell, HC; Pettinger, WA | 1 |
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| Brunner, HR; Laragh, JH | 1 |
| Marks, LS; Maxwell, MH | 1 |
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| Boerth, RC; Braren, V; Dean, RH; Favre, L; Hollifield, JW | 1 |
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| Bartter, FC; Lake, CR; Mitchell, JR; Pool, JL; Rollins, DE; Taylor, AA | 1 |
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| Oelkers, W | 1 |
| Beckerhoff, R; Furrer, J; Nussberger, J; Siegenthaler, W; Vetter, W | 1 |
| Brown, JJ; Fraser, R; Leckie, B; Lever, AF; Morton, JJ; Padfield, PL; Robertson, JI; Semple, PF | 1 |
| Friedman, A; Johnston, CI; Suthers, MB; Walter, NM | 1 |
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| Schölkens, BA | 3 |
| Gantt, CL | 2 |
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| Dietz, R; Ganten, D; Mann, JF; Rascher, W; Schömig, A | 1 |
| Brunner, HR; Gavras, H; Gavras, I; Liang, CS | 1 |
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| Anderson, G; Blackman, M; Farrell, BG; Parker, FB; Poirier, RA; Streeten, DH | 1 |
| Beevers, DG; Brown, JJ; Cumming, AM; Davies, DL; Fraser, R; Lever, AF; Mason, P; Morton, JJ; Robertson, JI; Tree, M | 1 |
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| McGiff, JC | 2 |
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| Botalla, L; Cremoncini, C; Cremoncini, M; Libroia, A; Vignati, E | 1 |
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| Barrett, JD; Eggena, P; Sambhi, MP | 1 |
| Coel, MN; Emarine, CW; Levy, SB; Stone, RA; Talner, LB | 1 |
| Schilling, A | 1 |
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| Goto, A; Ikeda, T; Ishii, M; Matsuoka, H; Murao, S; Nakamura, Y; Nishiyama, K; Takeda, T | 1 |
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| Fujita, T; Nagaoka, A; Shibota, M; Shino, A | 2 |
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| Adlin, VE; Channick, BJ; Kanefsky, TM; Marks, AD; Marks, DB | 1 |
| Becker, CE; Benowitz, NL | 1 |
| Adams, DF; Bavli, S; Borucki, LJ; Brown, C; Dluhy, R; Hollenberg, NK; Leung, F; Moore, T; Passan, D; Solomon, HS; Williams, GH | 1 |
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| Brody, MJ; Fink, GD | 1 |
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| Karlberg, BE; Tolagen, K | 1 |
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| de Jesús Hernández, M; Karchmer, S; Shor Pinsker, V; Zamora Orozco, J | 1 |
| Ferriss, JB; Gonggrijp, H; Long, AA; O'Sullivan, DJ; Sullivan, PA | 1 |
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| Barjon, P; Deschodt, G; Fourcade, J; Mimran, A | 1 |
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| D'Hollander, A; Ducobu, J; Guerisse, P; Vanherweghem, JL | 1 |
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| Eguchi, T; Kondo, K; Nakamura, R; Okuno, T; Saruta, T; Yasui, T | 1 |
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| Miyamori, I; Morimoto, S; Saito, Y; Uchida, K; Yamamoto, I | 1 |
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| Broughton Pipkin, F; Oats, JJ; Symonds, EM | 1 |
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| Haruyama, K; Miura, T; Mizuno, K; Nakajima, G; Ogawa, S | 1 |
| Dietz, R; Ganten, D; Haebara, H; Hoffman, WE; Mann, JF; Phillips, MI; Schelling, P | 1 |
| Bazanova, OM; Dzizinskiĭ, AA; Genina, VA; Nedel'kina, SV; Shterental', ISh | 1 |
| Matsuganova, TN; Rodionov, IuIa; Rodionov, VIa | 1 |
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| Baumann, H; Martin, G | 1 |
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| Dietz, R; Gross, F; Haebara, H; Lüth, JB; Mann, JF; Schömig, A | 1 |
| Kolloch, RE; Krück, F; Redlich, B; Stumpe, KO; Vetter, H | 1 |
| Dietz, R; Gross, F; Lüth, JB; Mann, JF | 1 |
| Dietz, R; Ganten, D; Haebara, H; Lüth, JB; Mann, JF; Phillips, MI | 1 |
| Case, DB; Keim, HJ; Laragh, JH; Sealry, JE; Wallace, JM | 1 |
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| Bavli, SZ; Dluhy, RG; Hollenberg, NK; Mersey, JH; Moore, TJ; Solomon, HS; Williams, GH | 1 |
| Chrysant, SG; de Carvalho, JG; Dunn, FG; Froholich, ED; Kem, DC | 1 |
| Krakoff, LR; Ribeiro, AB; Vlachakis, ND | 1 |
| Gibney, R; Kirschenbaum, MA; Lifschitz, MD; Rosenblatt, SG | 1 |
| Giese, J; Ibsen, H; Kappelgaard, AN; Nielsen, MD | 1 |
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| Beevers, DG; Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Lever, AF; Mason, P; Neville, AM; Robertson, JI | 1 |
| Berthelot, A; Gairard, A | 1 |
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| Ledingham, JG; McGrath, BP | 1 |
| Erhard, R; Losse, H; Peters, P; Wagner, H; Wessels, F | 1 |
| Kaufman, JJ; Marks, L; Maxwell, MH; Waks, UA; Zawada, ET | 1 |
| Barjon, P; Mimran, A; Mion, C; Shaldon, S | 1 |
| Barbanel, C; Bichara, M; Fouchard, M; Funck-Brentano, JL; Grüfeld, JP; Meyer, P | 1 |
| Bumpus, FM; Khairallah, PA; Khosla, MC; Muñoz-Ramírez, H | 1 |
| Dietz, R; Ganten, D; Haebara, H; Mann, JF; Phillips, MI | 1 |
| Anderson, GH; Dalakos, TG; Elias, AN; Streeten, DH | 1 |
| Brunner, HR; Ferguson, RK; Gavras, H; Jaeger, P; Kirchertz, EJ | 1 |
| Comsulea, L; Cristodorescu, R; Deutsch, G; Gavrilescu, S | 1 |
| Fukiyama, K; Omae, T; Takishita, S; Tamaki, K | 1 |
| Kheder, MA; Levenson, JM; Levy, BI; Safar, ME; Simon, AC; Weiss, YA | 1 |
| Berecek, KH; Bohr, DF | 1 |
| Adlin, EV; Channick, BJ; Kim, YN; Marks, AD; Marks, DB; Moctezuma, J | 1 |
| Kato, E; Kondo, K; Nakamura, R; Oguro, T; Ozawa, Y; Saito, I; Saruta, T; Yamagami, K | 1 |
| Battino, A; Corvol, P; Girardet, JP; Lardoux, H; Maurice, P; Milliez, P | 1 |
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| Broughton Pipkin, F; Hunter, JC; Oats, J; Symonds, M | 1 |
| Cowley, AW; DeClue, JW; Guyton, AC; Lohmeier, TE | 1 |
| Thorball, N | 2 |
| Arlart, IP; Rosenthal, J; Wagner, H | 1 |
| Mueller-Heubach, E; Thompson, DS | 1 |
| Jennings, JC; Morrison, JC; Palmer, ET; Ratts, TE; Schoeneberger, AA; Sullivan, JM | 1 |
| Coleman, TG; Cowley, AW; DeClue, JW; Guyton, AC; McCaa, RE; Norman, RA | 1 |
| Kono, T | 1 |
| Dietz, R; Gross, F; Haebara, H | 1 |
| Baer, L; Niarchos, AP; Radichevich, I | 1 |
| Arlart, I; Rosenthal, J | 1 |
| Seino, M | 1 |
| Abe, K; Aoyagi, H; Chiba, S; Irokawa, N; Itoh, T; Kusaka, T; Miyazaki, S; Otsuka, Y; Ritsu, K; Saitoh, K; Sakurai, Y; Seino, M; Yasujima, M; Yoshinaga, K | 1 |
| Beyer, J; Hayduk, K; Liebau, G; Steiner, B | 1 |
| Iwatsuka, H; Nagaoka, A; Toyoda, S | 1 |
| Bing, RF; Pohl, JE; Swales, JD; Thurston, H | 1 |
| Baldet, P; Barjon, P; Fourcade, JC; Leckie, BJ; Mimran, A; Navratil, H | 1 |
| Krück, F; Overlack, A; Stumpe, KO | 1 |
| Dzizinskiĭ, AA; Genina, VA; Podkolodnaia, OA; Shterental', ISh | 1 |
| Anderson, G; Eich, R; Mookherjee, S; Obeid, A; Smulyan, H; Warner, R | 1 |
| Ishimaru, K; Matsuda, M; Mori, H; Oshima, I; Saito, H; Saito, S; Susaki, S | 1 |
| Ganten, D; Ganten, U; Johnson, AK; Mann, JF; Schaz, K; Simon, W | 1 |
| Möhring, J | 1 |
| Johnston, CI; Matthews, PG; Maydom, BW; McGrath, BP; Walter, NM | 1 |
| Hökfelt, B; Hulthén, L | 1 |
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| Alcazar De La Ossa, JM; Gutíerrez Millet, V; Jarillo, MD; Morales, JM; Pérez Díaz, V; Ródicio, JL; Ruilope, LM | 1 |
| Aoi, W; Doi, Y; Hashiba, K; Kuramochi, M; Norimura, T; Okajima, S; Suzuki, S; Tasaki, S | 1 |
| Abe, K; Chiba, S; Haruyama, T; Imai, Y; Irokawa, N; Ito, T; Kusaka, T; Otsuka, Y; Ritsu, K; Saito, K; Sakurai, Y; Sato, M; Seino, M; Yasujima, M; Yoshinaga, K | 1 |
| De Mey, C; Vanhoutte, PM; Zonnekeyn, L | 1 |
| Aisenbrey, G; Burke, TJ; Cadnapaphornchai, P; McDonald, KM; Schrier, RW | 1 |
| Anderson, GH; Dalakos, TG; Elias, AN; Schroeder, ET; Streeten, DH | 1 |
| Ackerly, JA; Ayers, CR; Carey, RM; Peach, MJ; Vaughan, ED | 1 |
| Kuczyńska-Sicińska, J | 3 |
| Keogh, B; Kirdani, R; Mittleman, A; Murphy, GP; Sandberg, AA | 1 |
| Bergman, B; Kågedal, B; Karlberg, BE; Tegler, L; Tolagen, K | 1 |
| Cannon, PJ; Gavras, H; Oliver, JA | 1 |
| Markiewicz, A | 1 |
| Kaulhausen, H; Klingsiek, L | 1 |
| Ganten, D; Gross, F | 1 |
| Adams, DF; Hollenberg, NK | 1 |
| Gramann, W; Kolloch, R; Krück, F; Stumpe, KO; Vetter, H | 2 |
| Davis, JO | 2 |
| Weir, RJ | 1 |
| McGiff, JC; Vane, JR | 2 |
| Barrett, JC; Eggena, P; Sambhi, MP; Thananopavarn, C; Tuck, M; Wiedeman, CE | 1 |
| Alexandre, JM; Corvol, P; Meignan, M; Ménard, J | 1 |
| Christlieb, AR | 2 |
| Appel, E; Heidland, A; Palm, D; Röckel, A | 1 |
| Chand, S; Gant, NF; Jimenez, JM; MacDonald, PC; Whalley, PJ | 1 |
| Bhattacharya, BK; Dadkar, NK; Dohadwalla, AN | 1 |
| Beevers, DG; Morton, JJ; Nelson, CS; Padfield, PL; Titterington, M; Tree, M | 1 |
| Anderson, GH; Dalakos, TG; Streeten, DH | 2 |
| Fregly, MJ; Fregly, MS | 1 |
| Dinsdale, HB; Nag, S; Robertson, DM | 1 |
| Brooks, B; Byers, LW; Leach, BE; Muirhead, EE; Pitcock, JA; Rightsel, WA | 1 |
| Hoffman, WE; Phillips, MI; Schmid, PG; Wilson, E | 1 |
| Haack, D; Möhring, B; Möhring, J; Petri, M | 1 |
| Anderson, GH; Streeten, DH | 1 |
| Swales, JD; Thurston, H | 3 |
| Haberland, GL | 1 |
| Maxwell, MH; Varady, P | 1 |
| Barrett, JD; Eggena, P; Sambhi, MP; Thananopavarn, C; Tuck, M; Wiedman, C | 1 |
| Hoffman, WE; Phillips, MI; Schmid, PG | 1 |
| Gruskin, AB; Hiner, LB | 1 |
| Ayers, CR; Carey, RM; Katholi, RE; Morton, CL; Vaughan, ED; Yancey, MR | 1 |
| Buckley, JP; Jandhyala, BS; Singh, S; Steenberg, ML | 1 |
| Dluhy, RG; Moore, TJ; Williams, GH | 1 |
| Bavli, SZ; Dluhy, RG; Greenfield, M; Himathongkam, T; Moore, TJ; Williams, GH | 1 |
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| Becker, RA; Evans, GT; Franks, RC; Hayashi, RH; Morris, K | 1 |
| Anderson, GH; Dalakos, TG; Elias, A; Streeten, DH; Tomycz, N | 1 |
| Boddy, K; Brown, JJ; Davies, DL; Fraser, R; Kremer, D; Lever, AF; Morton, JJ; Robertson, JI | 1 |
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| Robertson, JI | 3 |
| Peck, TM | 1 |
| Zanchetti, AS | 1 |
| Benedict, CR; Ledingham, JG; McGrath, BP | 1 |
| Kim, KS; Miyamori, I; Morimoto, S; Takeda, R; Yamamoto, I | 1 |
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| Kolloch, RE; Overlack, A; Stumpe, KO | 1 |
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| Casado, S; Hernando, L; Liaño, F | 1 |
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| Barjon, P; Mathieu, MN; Mimran, A; Mion, C; Polito, C; Shaldon, S | 1 |
| Hara, A; Kawai, C; Kira, J; Matsunaga, M; Ogino, K; Pak, C; Yamamoto, J | 1 |
| Fukiyama, K; Kumamoto, K; Noda, Y; Omae, T; Yamamoto, Y | 1 |
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| Dluhy, RG; Greenfield, M; Moore, TJ; Tuck, ML; Williams, GH | 1 |
| Beckerhoff, R; Cottier, P; Redlich, B; Siegenthaler, W; Vetter, H; Vetter, W | 1 |
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1032 review(s) available for angiotensin ii and Hypertension
| Article | Year |
|---|---|
Evolutionary trilogy of malaria, angiotensin II and hypertension: deeper insights and the way forward.
Topics: Angiotensin I; Angiotensin II; Humans; Hypertension; Malaria; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renin-Angiotensin System | 2022 |
Molecular Interactions of Arterial Hypertension in Its Target Organs.
Topics: Angiotensin II; Animals; Arterial Pressure; Arteries; Biomarkers; Disease Susceptibility; Endoplasmic Reticulum Stress; Humans; Hypertension; Immune System; Matrix Metalloproteinases; Organ Specificity; Oxidative Stress; Reactive Oxygen Species; Renin; Vascular Remodeling | 2021 |
ATRAP, a receptor-interacting modulator of kidney physiology, as a novel player in blood pressure and beyond.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney; Mice; Receptor, Angiotensin, Type 1 | 2022 |
Angiotensin II and the Cardiac Parasympathetic Nervous System in Hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Heart; Humans; Hypertension; Parasympathetic Nervous System; Receptors, Angiotensin; Renin-Angiotensin System; Vasoconstrictor Agents | 2021 |
Chronic Renin-Angiotensin System Activation Induced Neuroinflammation: Common Mechanisms Underlying Hypertension and Dementia?
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Brain; Cytokines; Dementia, Vascular; Humans; Hypertension; Inflammation; Peptide Fragments; Renin-Angiotensin System | 2022 |
Current Trends and Applications of Food-derived Antihypertensive Peptides for the Management of Cardiovascular Disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiovascular Diseases; Hypertension; Meat; Nitric Oxide; Peptides | 2022 |
AT1 Receptors: Their Actions from Hypertension to Cognitive Impairment.
Topics: Adult; Angiotensin II; Blood Pressure; Cognitive Dysfunction; COVID-19; Humans; Hypertension; Middle Aged; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2022 |
Renin-Angiotensin Aldosterone System Inhibitors and COVID-19: A Systematic Review and Meta-Analysis Revealing Critical Bias Across a Body of Observational Research.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; COVID-19; Humans; Hypertension; Renin; Renin-Angiotensin System; SARS-CoV-2 | 2022 |
Renin-Angiotensin-Aldosterone Inhibitors and COVID-19 Infection.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; COVID-19 Drug Treatment; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Pandemics; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Retrospective Studies; SARS-CoV-2 | 2022 |
Angiotensin-(1-9) in hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Hypertension; Imidazoles; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sulfonamides; Thiophenes | 2022 |
Salt Sensitivity of Blood Pressure in Women.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Receptors, Mineralocorticoid; Sodium Chloride, Dietary | 2023 |
Influence and implications of the renin-angiotensin-aldosterone system in obstructive sleep apnea: An updated systematic review and meta-analysis.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Hormones; Humans; Hypertension; Renin; Renin-Angiotensin System; Sleep Apnea, Obstructive | 2023 |
Does the Naked Emperor Parable Apply to Current Perceptions of the Contribution of Renin Angiotensin System Inhibition in Hypertension?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetes Mellitus, Type 2; Humans; Hypertension; Renin; Renin-Angiotensin System | 2022 |
Antihypertensive Agents and Incident Alzheimer's Disease: A Systematic Review and Meta-Analysis of Observational Studies.
Topics: Alzheimer Disease; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension | 2022 |
Role of Gi proteins in the regulation of blood pressure and vascular remodeling.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Blood Pressure; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Vascular Remodeling | 2023 |
Role of angiotensin receptor blockers in the context of Alzheimer's disease.
Topics: Alzheimer Disease; Angiotensin II; Angiotensin Receptor Antagonists; Humans; Hypertension; Receptor, Angiotensin, Type 1 | 2023 |
Cardiovascular Protection with a Long-Acting GLP-1 Receptor Agonist Liraglutide: An Experimental Update.
Topics: Angiotensin II; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glucagon-Like Peptide-1 Receptor; Heart Failure; Humans; Hypertension; Hypoglycemic Agents; Liraglutide | 2023 |
Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis.
Topics: Angiotensin II; Diabetes Mellitus; Diabetic Retinopathy; Glucose; Humans; Hyperglycemia; Hypertension; Neuroglia; Palmitic Acid | 2023 |
Metabolic Syndrome and Cardiac Remodeling Due to Mitochondrial Oxidative Stress Involving Gliflozins and Sirtuins.
Topics: Angiotensin II; Cardiovascular Diseases; Diabetes Mellitus; Fibrosis; Humans; Hypertension; Metabolic Syndrome; Oxidative Stress; Sirtuins; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Remodeling | 2023 |
ACE-Inhibitors in Hypertension: A Historical Perspective and Current Insights.
Topics: Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Cough; Humans; Hypertension; Renin-Angiotensin System | 2023 |
Angiotensin-Converting Enzyme and Hypertension: A Systemic Analysis of Various ACE Inhibitors, Their Side Effects, and Bioactive Peptides as a Putative Therapy for Hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Peptides | 2023 |
Nonatherosclerotic Renovascular Hypertension.
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renovascular; Renin; Sodium | 2023 |
New Viral Diseases and New Possible Remedies by Means of the Pharmacology of the Renin-Angiotensin System.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; COVID-19; Humans; Hypertension; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H7N9 Subtype; Peptidyl-Dipeptidase A; Renin-Angiotensin System; SARS-CoV-2 | 2023 |
Interaction of Angiotensin II AT1 Receptors with Purinergic P2X Receptors in Regulating Renal Afferent Arterioles in Angiotensin II-Dependent Hypertension.
Topics: Adenosine Triphosphate; Angiotensin II; Arterioles; Humans; Hypertension; Kidney; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Purinergic P2X | 2023 |
Angiotensin Regulation of Vascular Homeostasis: Exploring the Role of ROS and RAS Blockers.
Topics: Angiotensin II; Homeostasis; Humans; Hypertension; NADPH Oxidases; Reactive Oxygen Species; Renin-Angiotensin System | 2023 |
Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Cytokines; Endothelial Cells; Humans; Hypertension; Peripheral Vascular Diseases; SARS-CoV-2 | 2023 |
Novel Pharmacological Approaches in the Treatment of Hypertension: A Focus on RNA-Based Therapeutics.
Topics: Angiotensin II; Angiotensinogen; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Humans; Hypertension; Renin-Angiotensin System; RNA, Small Interfering | 2023 |
Targeting Angiotensinogen With
Topics: Acetylgalactosamine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Blood Pressure; Humans; Hypertension; Renin; Renin-Angiotensin System; RNA, Small Interfering | 2023 |
ACE-Triggered Hypertension Incites Stroke: Genetic, Molecular, and Therapeutic Aspects.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Macrophages; Mice; MicroRNAs; Mutation, Missense; Myocytes, Smooth Muscle; Neuroglia; Peptidyl-Dipeptidase A; Polymorphism, Single Nucleotide; Renin-Angiotensin System; Stroke | 2020 |
Recent Research Advances in Renin-Angiotensin-Aldosterone System Receptors.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Humans; Hypertension; Proto-Oncogene Mas; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2020 |
Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?
Topics: Angiotensin II; Angiotensinogen; Animals; Humans; Hypertension; Kidney; Low Density Lipoprotein Receptor-Related Protein-2; Mice; Renin; Renin-Angiotensin System | 2020 |
The Malaria-High Blood Pressure Hypothesis: Revisited.
Topics: Angiotensin II; Calcium Signaling; Cell Survival; Cytokines; Developing Countries; Endothelium; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Inflammation; Malaria; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neurotransmitter Agents; Nitric Oxide; Peptidyl-Dipeptidase A; Pre-Eclampsia; Pregnancy; Renin-Angiotensin System | 2020 |
Oxidative Stress: A Unifying Paradigm in Hypertension.
Topics: Aldosterone; Angiotensin II; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Inflammation; Intercellular Signaling Peptides and Proteins; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sex Factors; Signal Transduction; Vascular Remodeling; Vascular Stiffness; Vasoconstriction | 2020 |
Targeting Brain Aminopeptidase A: A New Strategy for the Treatment of Hypertension and Heart Failure.
Topics: Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Brain; Clinical Trials as Topic; Disulfides; Glutamyl Aminopeptidase; Heart Failure; Humans; Hypertension; Myocardial Infarction; Renin-Angiotensin System; Sulfonic Acids | 2020 |
Angiotensin II, Hypercholesterolemia, and Vascular Smooth Muscle Cells: A Perfect Trio for Vascular Pathology.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Cells, Cultured; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertension; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction | 2020 |
Role of the renin-angiotensin system in the development of severe COVID-19 in hypertensive patients.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Hypertension; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Renin-Angiotensin System; Risk Factors; SARS-CoV-2 | 2020 |
The Role of the Renin-Angiotensin-Aldosterone System in Preeclampsia: a Review.
Topics: Angiotensin II; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Renin; Renin-Angiotensin System | 2020 |
Reactive Oxygen Species: Modulators of Phenotypic Switch of Vascular Smooth Muscle Cells.
Topics: Angiotensin II; Antioxidants; Atherosclerosis; Biomarkers; Cardiovascular Agents; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Fibroblast Growth Factors; Gene Expression Regulation; Graft Occlusion, Vascular; Humans; Hypertension; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phenotype; Reactive Oxygen Species; Signal Transduction | 2020 |
Coronavirus Disease 2019 and Hypertension: The Role of Angiotensin-Converting Enzyme 2 and the Renin-Angiotensin System.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Comorbidity; COVID-19; Humans; Hypertension; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Signaling System; Peptide Fragments; Protective Factors; Receptors, Coronavirus; Renin-Angiotensin System; Risk Factors; SARS-CoV-2; Up-Regulation | 2020 |
Myeloid cells, tissue homeostasis, and anatomical barriers as innate immune effectors in arterial hypertension.
Topics: Angiotensin II; Animals; Antimicrobial Cationic Peptides; Complement Activation; Desoxycorticosterone Acetate; Dysbiosis; Gastrointestinal Microbiome; Homeostasis; Humans; Hypertension; Immunity, Innate; Inflammasomes; Intestinal Mucosa; Mice; Models, Animal; Myeloid Cells; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Skin; Sodium; Sodium Chloride, Dietary; Toll-Like Receptors; Water-Electrolyte Balance | 2021 |
From Angiotensin II to Cyclic Peptides and Angiotensin Receptor Blockers (ARBs): Perspectives of ARBs in COVID-19 Therapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; COVID-19; COVID-19 Drug Treatment; Humans; Hypertension; Renin-Angiotensin System; SARS-CoV-2 | 2021 |
Contribution of ADAM17 and related ADAMs in cardiovascular diseases.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Aortic Aneurysm; Cardiovascular Diseases; Cytokines; Humans; Hypertension; Signal Transduction | 2021 |
Role of angiotensin II in chronic intermittent hypoxia-induced hypertension and cognitive decline.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Cognition; Cognitive Dysfunction; Humans; Hypertension; Hypoxia; Renin-Angiotensin System; Risk Factors; Signal Transduction; Sleep Apnea Syndromes | 2021 |
Kidney and epigenetic mechanisms of salt-sensitive hypertension.
Topics: Aging; Aldosterone; Angiotensin II; Animals; DNA Methylation; Fetal Nutrition Disorders; Glucuronidase; Humans; Hypertension; Klotho Proteins; Obesity; Oxidative Stress; Receptors, Mineralocorticoid; Renal Circulation; Sodium Chloride, Dietary; Wnt Signaling Pathway | 2021 |
Malaria link of hypertension: a hidden syndicate of angiotensin II, bradykinin and sphingosine 1-phosphate.
Topics: Angiotensin II; Blood Pressure; Bradykinin; Comorbidity; Female; Humans; Hypertension; Lysophospholipids; Malaria; Male; Pregnancy; Sphingosine | 2021 |
Novel therapeutics for the treatment of hypertension and its associated complications: peptide- and nonpeptide-based strategies.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Humans; Hypertension; Renin-Angiotensin System | 2021 |
Angiotensin II-Vasopressin Interactions in The Regulation of Cardiovascular Functions. Evidence for an Impaired Hormonal Sympathetic Reflex in Hypertension and Congestive Heart Failure.
Topics: Angiotensin II; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Heart Failure; Humans; Hypertension; Receptor Cross-Talk; Reflex, Abnormal; Sympathetic Nervous System; Vasopressins | 2021 |
Novel roles of the renal angiotensin-converting enzyme.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Diabetic Nephropathies; Gene Expression Regulation; Humans; Hypertension; Kidney; Mice; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Gene Expression Regulation; Humans; Hypertension; Kidney Tubules, Proximal; Mice; Mice, Knockout; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Novel Targets for Hypertension Drug Discovery.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Chemokines; Drug Discovery; Humans; Hypertension | 2021 |
Pathophysiology of Hypertension: The Mosaic Theory and Beyond.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Vessels; Body Fluids; Central Nervous System; Humans; Hypertension; Inflammation; Kidney; Microbiota; Reactive Oxygen Species; Risk Factors; Sodium Chloride; Vasoconstrictor Agents | 2021 |
Role of Rho in Salt-Sensitive Hypertension.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Nitric Oxide; Nitric Oxide Synthase; rho-Associated Kinases; Sodium Chloride, Dietary; Sympathetic Nervous System; Vasoconstriction | 2021 |
The evolving complexity of the collecting duct renin-angiotensin system in hypertension.
Topics: Angiotensin II; Humans; Hypertension; Kidney Tubules, Collecting; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System | 2021 |
DNA Methylation of the Angiotensinogen Gene,
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Cardiovascular Diseases; CCAAT-Enhancer-Binding Proteins; Cytochrome P-450 CYP11B2; DNA Methylation; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation; Humans; Hypertension; Promoter Regions, Genetic; Transcription Factors | 2021 |
Tracing angiotensin II's yin-yang effects on cardiovascular-renal pathophysiology.
Topics: Angiotensin II; Cachexia; Humans; Hypertension; Kidney; Renin-Angiotensin System | 2023 |
Fifty years of research on the brain renin-angiotensin system: what have we learned?
Topics: Angiotensin II; Brain; Humans; Hypertension; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2021 |
The interplay between Angiotensin II, TLR4 and hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; Brain; Humans; Hypertension; Immunity, Innate; Inflammation; Kidney; Renin-Angiotensin System; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Purinergic P2Y
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Humans; Hypertension; Isothiocyanates; Molecular Targeted Therapy; Purinergic P2 Receptor Antagonists; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Purinergic P2; Thiourea | 2017 |
Role of Collecting Duct Renin in the Pathogenesis of Hypertension.
Topics: Angiotensin II; Animals; Humans; Hypertension; Kidney Tubules, Collecting; Kidney Tubules, Distal; Kidney Tubules, Proximal; Renin; Renin-Angiotensin System | 2017 |
Sex differences in angiotensin II-stimulated fluid intake.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Drinking; Estrogens; Female; Humans; Hypertension; Male; Receptors, Estrogen; Renin-Angiotensin System; Sex Factors; Signal Transduction | 2017 |
Endoplasmic Reticulum Stress, a Driver or an Innocent Bystander in Endothelial Dysfunction Associated with Hypertension?
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endoplasmic Reticulum Stress; Endothelium, Vascular; Humans; Hypertension; Vascular Diseases | 2017 |
Current evidence on the use of anti-RAAS agents in congenital or acquired solitary kidney.
Topics: Adult; Age Factors; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Child; Disease Progression; Female; Humans; Hypertension; Kidney; Male; Protective Agents; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sex Factors; Solitary Kidney | 2017 |
Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Humans; Hypertension; Oligopeptides; Peptide Fragments; Protective Factors; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Vasoconstriction | 2018 |
Changes in the pancreas caused by different types of hypertension.
Topics: Angiotensin II; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin Resistance; Pancreas | 2017 |
Mechanisms and mediators of hypertension induced by erythropoietin and related molecules.
Topics: Angiotensin II; Animals; Erythropoietin; Hemoglobins; Humans; Hypertension | 2018 |
Effects of natural peptides from food proteins on angiotensin converting enzyme activity and hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Food; Food Analysis; Humans; Hypertension; Peptides; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2019 |
Neuroinflammation and sympathetic overactivity: Mechanisms and implications in hypertension.
Topics: Angiotensin II; Animals; Autonomic Nervous System Diseases; Cytokines; Encephalitis; Humans; Hypertension; Neuroglia; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2018 |
Therapeutic Vaccines for Hypertension: a New Option for Clinical Practice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Oligopeptides; Vaccines | 2018 |
Independent regulation of renin-angiotensin-aldosterone system in the kidney.
Topics: Angiotensin II; Angiotensinogen; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Kidney; Kidney Diseases; Renin; Renin-Angiotensin System | 2018 |
Regulation of sympathetic vasomotor activity by the hypothalamic paraventricular nucleus in normotensive and hypertensive states.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cardiovascular System; Disease Models, Animal; Excitatory Postsynaptic Potentials; Exercise Therapy; GABAergic Neurons; Glutamic Acid; Humans; Hypertension; Inflammation Mediators; Neural Inhibition; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Synaptic Transmission; Vasomotor System | 2018 |
Temporal Frame of Immune Cell Infiltration during Heart Failure Establishment: Lessons from Animal Models.
Topics: Angiotensin II; Animals; Aorta; B-Lymphocytes; Cardiomegaly; Cell Movement; Constriction, Pathologic; Cytokines; Disease Models, Animal; Endomyocardial Fibrosis; Heart Failure; Humans; Hypertension; Mice; Monocytes; T-Lymphocytes; Time Factors; Ventricular Dysfunction, Left | 2018 |
Angiotensin II and vascular damage in hypertension: Role of oxidative stress and sympathetic activation.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Brain; Humans; Hypertension; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Risk Factors; Signal Transduction; Sympathetic Nervous System | 2019 |
The renin-angiotensin-aldosterone system and its suppression.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Heart Failure; Hypertension; Kidney Diseases; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System | 2019 |
The (pro)renin receptor: an emerging player in hypertension and metabolic syndrome.
Topics: Angiotensin II; Animals; Autophagy; Blood Pressure; Disease Models, Animal; Glucose; Humans; Hypertension; Lipid Metabolism; Metabolic Syndrome; Proton-Translocating ATPases; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Vacuolar Proton-Translocating ATPases; Wnt Signaling Pathway | 2019 |
Obesity, kidney dysfunction and hypertension: mechanistic links.
Topics: Adipokines; Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Kidney Tubules; Leptin; Obesity; Oxidative Stress; Pro-Opiomelanocortin; Receptor, Melanocortin, Type 4; Receptors, Mineralocorticoid; Renal Reabsorption; Renin; Sodium; Sympathetic Nervous System | 2019 |
Levels of angiotensin peptides in healthy and cardiovascular/renal-diseased paediatric population-an investigative review.
Topics: Adolescent; Age Factors; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Child; Child, Preschool; Female; Humans; Hypertension; Infant; Infant, Newborn; Kidney Failure, Chronic; Male; Peptide Fragments; Renin-Angiotensin System | 2019 |
Orally Active Aminopeptidase A Inhibitor Prodrugs: Current State and Future Directions.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Glutamyl Aminopeptidase; Humans; Hypertension; Prodrugs; Rats; Renin-Angiotensin System | 2019 |
The Key Role of Epithelial to Mesenchymal Transition (EMT) in Hypertensive Kidney Disease.
Topics: Angiotensin II; Animals; Biomarkers; Disease Susceptibility; Endothelins; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Hypertension; Hypertension, Renal; Nephritis | 2019 |
[The cortical collecting duct plays a pivotal role in the kidney's local renin-angiotensin system].
Topics: Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Female; Fetus; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney Tubules, Collecting; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Renin-Angiotensin System | 2013 |
Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease.
Topics: Aging; Aldosterone; Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Carotid Arteries; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Mice; Muscle, Smooth, Vascular; Placenta Growth Factor; Pregnancy Proteins; Receptors, Mineralocorticoid; Signal Transduction | 2013 |
Organ selective regulation of sympathetic outflow by the brain Angiotensin system.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Humans; Hypertension; Organ Specificity; Sympathetic Nervous System | 2013 |
Aldosterone mediates cardiac fibrosis in the setting of hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Fibrosis; Heart Diseases; Humans; Hypertension | 2013 |
Regulation of aldosterone biosynthesis by the Kir3.4 (KCNJ5) potassium channel.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Aldosterone; Angiotensin II; Cell Membrane; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Hypertension; Mutation; Potassium; Zona Glomerulosa | 2013 |
Role of angiotensin II type 1 receptor-activating antibodies in solid organ transplantation.
Topics: Angiotensin II; Antibodies; HLA Antigens; Humans; Hypertension; Organ Transplantation; Receptor, Angiotensin, Type 2; Transplantation Immunology | 2013 |
Sex differences in angiotensin II- and aldosterone-induced hypertension: the central protective effects of estrogen.
Topics: Aldosterone; Angiotensin II; Animals; Brain; Estrogens; Humans; Hypertension; Models, Biological; Renin-Angiotensin System; Sex Factors | 2013 |
The intrarenal renin-angiotensin system: does it exist? Implications from a recent study in renal angiotensin-converting enzyme knockout mice.
Topics: Angiotensin II; Animals; Hypertension; Kidney Diseases; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2013 |
Role of mitochondrial oxidative stress in hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Cardiovascular System; Humans; Hypertension; Mechanotransduction, Cellular; Mitochondria; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Risk Factors | 2013 |
Interactions of neuropeptide y, catecholamines, and angiotensin at the vascular neuroeffector junction.
Topics: Angiotensin I; Angiotensin II; Animals; Catecholamines; Humans; Hypertension; Neuroeffector Junction; Neuropeptide Y; Peptide Fragments; Sympathetic Nervous System | 2013 |
Recent progress in the treatment of cardiovascular disease using olmesartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Coronary Artery Disease; Coronary Stenosis; Disease Models, Animal; Humans; Hypertension; Imidazoles; Plaque, Atherosclerotic; Tetrazoles | 2014 |
Proinflammation: the key to arterial aging.
Topics: Aged; Aging; Angiotensin II; Animals; Antigens, Surface; Arteries; Arteritis; Atherosclerosis; Calpain; Chemokine CCL2; Endothelin-1; Humans; Hypertension; Inflammation; Inflammation Mediators; Matrix Metalloproteinase 2; Middle Aged; Milk Proteins; Muscle, Smooth, Vascular; Nitric Oxide; Reactive Oxygen Species; Receptors, CCR2; Transforming Growth Factor beta1 | 2014 |
Renal angiotensin-converting enzyme and blood pressure control.
Topics: Angiotensin II; Animals; Blood Pressure; Body Water; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Signal Transduction; Sodium; Water-Electrolyte Balance; Water-Electrolyte Imbalance | 2014 |
ACE2: angiotensin II/angiotensin-(1-7) balance in cardiac and renal injury.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Heart Diseases; Humans; Hypertension; Kidney Diseases; Peptide Fragments; Peptidyl-Dipeptidase A | 2014 |
Angiotensin-(1-12): a chymase-mediated cellular angiotensin II substrate.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Chymases; Heart; Humans; Hypertension; Substrate Specificity | 2014 |
Actions of circulating angiotensin II and aldosterone in the brain contributing to hypertension.
Topics: Aldosterone; Angiotensin II; Brain Chemistry; Humans; Hypertension; Neurotransmitter Agents; Renin-Angiotensin System | 2014 |
New components of the renin-angiotensin system: alamandine and the MAS-related G protein-coupled receptor D.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Oligopeptides; Peptide Fragments; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Risk Assessment; Sensitivity and Specificity | 2014 |
Angiotensin II and vascular injury.
Topics: Angiotensin II; Animals; Atherosclerosis; Cardiovascular Diseases; Humans; Hypertension; Muscle, Smooth, Vascular; Oxidation-Reduction; Reactive Oxygen Species; Renin-Angiotensin System; Signal Transduction; Vascular Remodeling; Vascular System Injuries | 2014 |
[Renin-aldosterone and bone metabolism].
Topics: Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Bone and Bones; Calcium; Cardiovascular Diseases; Drug Discovery; Humans; Hypertension; Inflammation; Molecular Targeted Therapy; Osteoporosis; Oxidative Stress; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Mineralocorticoid; Renin; Renin-Angiotensin System | 2014 |
Renal generation of angiotensin II and the pathogenesis of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Kidney; Renin-Angiotensin System | 2014 |
Proinflammation of aging central arteries: a mini-review.
Topics: Aging; Angiotensin II; Animals; Arteries; Atherosclerosis; Haplorhini; Humans; Hypertension; Myocytes, Smooth Muscle; Rabbits; Rats; Signal Transduction; Tunica Intima; Tunica Media; Vascular Remodeling | 2014 |
Understanding the mechanisms of angiotensin II signaling involved in hypertension and its long-term sequelae: insights from Bartter's and Gitelman's syndromes, human models of endogenous angiotensin II signaling antagonism.
Topics: Angiotensin II; Bartter Syndrome; Gitelman Syndrome; Glucose; GTP-Binding Proteins; Humans; Hypertension; Insulin Resistance; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2014 |
Mineralocorticoid-induced sodium appetite and renal salt retention: evidence for common signaling and effector mechanisms.
Topics: Aldosterone; Angiotensin II; Animals; Appetite; Blood Pressure; Epithelial Sodium Channels; Humans; Hypertension; Kidney; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Receptors, Mineralocorticoid; Signal Transduction; Sodium Chloride; Water-Electrolyte Balance | 2014 |
Molecular mechanism of aggravation of hypertensive organ damages by short-term blood pressure variability.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Humans; Hypertension; Myocarditis; Myocardium; Rats; Receptors, Mineralocorticoid; Renin-Angiotensin System; Risk Factors; Signal Transduction; Time Factors; Ventricular Dysfunction | 2014 |
The intrarenal generation of angiotensin II is required for experimental hypertension.
Topics: Angiotensin II; Animals; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2015 |
Angiotensin and neurovascular coupling: beyond hypertension.
Topics: Alzheimer Disease; Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertension; NADPH Oxidases; Neurovascular Coupling; Receptor, Angiotensin, Type 1 | 2015 |
Development of DNA vaccines as an anti-hypertensive therapy or for anti-angiogenesis.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Antibody Formation; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Immunotherapy; Vaccines, DNA | 2015 |
Crosstalk between (Pro)renin receptor and COX-2 in the renal medulla during angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Humans; Hypertension; Kidney; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System | 2015 |
Angiotensin II and Cardiovascular-Renal Remodelling in Hypertension: Insights from a Human Model Opposite to Hypertension.
Topics: Angiotensin II; Bartter Syndrome; Cardiovascular System; Gitelman Syndrome; Humans; Hypertension; Kidney; Nitric Oxide; Oxidative Stress; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2015 |
Roles of collecting duct renin and (pro)renin receptor in hypertension: mini review.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Humans; Hypertension; Kidney Diseases; Peptidyl-Dipeptidase A; Rats; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Vacuolar Proton-Translocating ATPases | 2015 |
The compensatory renin-angiotensin system in the central regulation of arterial pressure: new avenues and new challenges.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Arterial Pressure; Drug Design; Humans; Hypertension; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2015 |
Regulation of Giα protein expression by vasoactive peptides in hypertension: molecular mechanisms.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Endothelin-1; Gene Expression Regulation; GTP-Binding Protein alpha Subunits; Humans; Hypertension; Models, Cardiovascular; Models, Immunological; Signal Transduction; Vasomotor System | 2014 |
The intrarenal renin-angiotensin system in hypertension.
Topics: Angiotensin I; Angiotensin II; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium | 2015 |
Role of stimulated intrarenal angiotensinogen in hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Biological Transport; Humans; Hypertension; Kidney Diseases; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Sodium; Vasoconstriction | 2015 |
Salt-Sensitive Hypertension: Perspectives on Intrarenal Mechanisms.
Topics: Angiotensin II; Angiotensins; Animals; Blood Pressure; Humans; Hypertension; Kidney; Kidney Tubules, Proximal; Models, Biological; Oxidative Stress; Renin-Angiotensin System; Sodium, Dietary | 2015 |
Role of neurons and glia in the CNS actions of the renin-angiotensin system in cardiovascular control.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Cell Communication; Central Nervous System; Humans; Hypertension; Neuroglia; Neurons; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2015 |
ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Kidney Diseases; Mice; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Rats; Renin-Angiotensin System | 2015 |
The roles of sensitization and neuroplasticity in the long-term regulation of blood pressure and hypertension.
Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Central Nervous System; Disease Models, Animal; Genetic Predisposition to Disease; Heredity; Humans; Hypertension; Neuronal Plasticity; Renin-Angiotensin System; Risk Factors; Signal Transduction; Time Factors | 2015 |
Angiotensin-II, the Brain, and Hypertension: An Update.
Topics: Angiotensin II; Animals; Brain; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; Hypertension; Oxidative Stress; Renin-Angiotensin System; Transcription Factors | 2015 |
Compromised blood-brain barrier permeability: novel mechanism by which circulating angiotensin II signals to sympathoexcitatory centres during hypertension.
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Capillary Permeability; Humans; Hypertension; Sympathetic Nervous System | 2016 |
Contribution of mitochondrial oxidative stress to hypertension.
Topics: Aging; Angiotensin II; Animals; Caloric Restriction; Humans; Hypertension; Mitochondria; Motor Activity; Oxidative Stress; Reactive Oxygen Species; Sirtuin 3; Smoking; Superoxide Dismutase | 2016 |
Salt, Angiotensin II, Superoxide, and Endothelial Function.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Humans; Hypertension; Sodium Chloride, Dietary; Superoxides | 2015 |
Angiotensins and Their Receptors in Cardiac and Vascular Injury.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Cardiovascular Diseases; Clinical Trials, Phase III as Topic; Humans; Hypertension; Renin-Angiotensin System | 2016 |
Intracellular angiotensin II as a regulator of muscle tone in vascular resistance vessels. Pathophysiological implications.
Topics: Angiotensin II; Cations, Monovalent; Epigenesis, Genetic; Humans; Hypertension; Ion Transport; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Potassium; Renin; Renin-Angiotensin System; Vascular Resistance | 2016 |
Neural Control of Non-vasomotor Organs in Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Humans; Hypertension; Obesity; Reactive Oxygen Species | 2016 |
The critical role of the central nervous system (pro)renin receptor in regulating systemic blood pressure.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Humans; Hypertension; Oligopeptides; Peptide Fragments; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System | 2016 |
Vascular Fibrosis in Aging and Hypertension: Molecular Mechanisms and Clinical Implications.
Topics: Aging; Angiotensin II; Endothelin-1; Endothelium, Vascular; Fibrosis; Humans; Hypertension; Matrix Metalloproteinases; Risk Factors; Smad Proteins; Transforming Growth Factor beta1; Vascular Stiffness | 2016 |
Recent Updates on the Proximal Tubule Renin-Angiotensin System in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Female; Humans; Hypertension; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Male; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin-Angiotensin System; Sodium; Sodium-Hydrogen Exchangers; Up-Regulation; Vacuolar Proton-Translocating ATPases | 2016 |
Clock genes and salt-sensitive hypertension: a new type of aldosterone-synthesizing enzyme controlled by the circadian clock and angiotensin II.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldosterone; Angiotensin II; Animals; Circadian Clocks; Circadian Rhythm; CLOCK Proteins; Hyperaldosteronism; Hypertension; Mice; Sodium Chloride, Dietary | 2016 |
Macrophages come to mind as keys to cognitive decline.
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Cognitive Dysfunction; Dementia, Vascular; Humans; Hypertension; Macrophages | 2016 |
Update on angiotensin AT2 receptors.
Topics: Angiotensin II; Angiotensin III; Animals; Blood Pressure; Humans; Hypertension; Kidney; Nitric Oxide; Receptor, Angiotensin, Type 2; Sodium | 2017 |
Sodium and potassium in the pathogenesis of hypertension: focus on the brain.
Topics: Aldosterone; Angiotensin II; Animals; Brain; Humans; Hypertension; Ouabain; Oxidative Stress; Potassium; Renin-Angiotensin System; Sodium; Sympathetic Nervous System; Vascular Resistance | 2017 |
Measurement of Cardiac Angiotensin II by Immunoassays, HPLC-Chip/Mass Spectrometry, and Functional Assays.
Topics: Angiotensin II; Animals; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hypertension; Immunoassay; Mass Spectrometry; Receptor, Angiotensin, Type 1 | 2017 |
Angiotensin Peptides as AT2 Receptor Agonists.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Gene Expression; Humans; Hypertension; Inflammation; Kinetics; Peptides; Peptidomimetics; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Sulfonamides; Thiophenes | 2017 |
Recent Advances in Immunity and Hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Hypertension, Pregnancy-Induced; Immune System; Immunity, Innate; Inflammation Mediators; Rats, Inbred SHR; Risk Factors; Signal Transduction; Sodium Chloride, Dietary | 2017 |
Newly developed angiotensin II-infused experimental models in vascular biology.
Topics: Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Blood Vessels; Female; Humans; Hypertension; Inflammation; Mice; Mice, Transgenic; Models, Biological; Neovascularization, Pathologic; Neovascularization, Physiologic; Postmenopause; Pre-Eclampsia; Pregnancy; Vascular Diseases | 2008 |
Role of the renin-angiotensin system in vascular inflammation.
Topics: Aldosterone; Angiotensin II; Animals; Capillary Permeability; Chemokine CCL2; Humans; Hypertension; NF-kappa B; Oxidative Stress; Renin-Angiotensin System; Vascular Cell Adhesion Molecule-1; Vasculitis | 2008 |
Neurohormonal regulation of the sympathetic nervous system: new insights into central mechanisms of action.
Topics: Angiotensin II; Blood Pressure; Endothelium, Vascular; Humans; Hypertension; Neurotransmitter Agents; Nitric Oxide; Reactive Oxygen Species; Renin-Angiotensin System; Sympathetic Nervous System | 2008 |
Pharmacologic modulation of ACE2 expression.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Disease Progression; Humans; Hypertension; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2008 |
The preclinical basis of the therapeutic evaluation of losartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Disease Models, Animal; Humans; Hypertension; Losartan; Rats; Rats, Inbred SHR; Renal Insufficiency; Renin-Angiotensin System | 1995 |
Angiotensin II vaccine: a novel approach in the treatment of hypertension.
Topics: Adult; Angiotensin II; Animals; Blood Pressure; Clinical Trials as Topic; Disease Models, Animal; Humans; Hypertension; Immunization; Models, Biological; Rats; Recombinant Proteins; Renin-Angiotensin System; Vaccination; Vaccines | 2008 |
[Therapeutic novelties in the management of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Amides; Angiotensin II; Antihypertensive Agents; Baroreflex; Carotid Sinus; Electric Stimulation Therapy; Electrodes, Implanted; Fumarates; Humans; Hypertension; Immunotherapy, Active; Oligopeptides; Randomized Controlled Trials as Topic; Renin; Vaccines, Synthetic | 2008 |
Tissue factor modulation by Angiotensin II: a clue to a better understanding of the cardiovascular effects of renin-angiotensin system blockade?
Topics: Angiotensin II; Animals; Cardiovascular System; Humans; Hypertension; NF-kappa B; Renin-Angiotensin System; Thromboplastin | 2008 |
The intracellular renin-angiotensin system in the heart.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Fibroblasts; Humans; Hypertension; Kidney; Muscle, Smooth, Vascular; Myocytes, Cardiac; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Ventricular Remodeling | 2009 |
CYT-006-AngQb, a vaccine against angiotensin II for the potential treatment of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Injections; Oligopeptides; Patents as Topic; Treatment Outcome; Vaccines, Synthetic | 2009 |
The renin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress.
Topics: Angiotensin II; Endothelium; Humans; Hypertension; Insulin Resistance; Kidney; Oxidative Stress; Renin-Angiotensin System; Risk Factors; Sodium; Sympathetic Nervous System | 2009 |
Arterial aging and subclinical arterial disease are fundamentally intertwined at macroscopic and molecular levels.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Angiotensin II; Animals; Coronary Artery Disease; Coronary Vessels; Endothelium, Vascular; Female; Humans; Hypertension; Male; Risk Factors | 2009 |
Oxidative stress and hypertension.
Topics: Angiotensin II; Blood Vessels; Central Nervous System; Humans; Hypertension; Inflammation; Kidney; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2009 |
Immunization against angiotensins for the treatment of hypertension.
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Humans; Hypertension; Renin-Angiotensin System; Treatment Outcome; Vaccination; Vaccines | 2010 |
The potential role of the angiotensin subtype 2 receptor in cardiovascular protection.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Arteriosclerosis; Humans; Hypertension; Kidney Diseases; Nitric Oxide; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin-Angiotensin System; Vasodilation | 2009 |
[The renin-angiotensin system].
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Arteries; Humans; Hypertension; Inflammation; Mineralocorticoid Receptor Antagonists; Models, Cardiovascular; Renin; Renin-Angiotensin System | 2009 |
Direct inhibition of renin: a physiological approach to treat hypertension and cardiovascular disease.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Drug Therapy, Combination; Fumarates; Humans; Hypertension; Renin; Renin-Angiotensin System | 2009 |
Region-specific changes in sympathetic nerve activity in angiotensin II-salt hypertension in the rat.
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertension; Kidney; Muscle, Skeletal; Rats; Sodium Chloride, Dietary; Sympathetic Nervous System; Viscera | 2010 |
A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link?
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Humans; Hypertension; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System | 2010 |
Angiotensin II, mechanotransduction, and pulsatile arterial hemodynamics in hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiac Output; Disease Models, Animal; Elasticity; Humans; Hypertension; Mechanotransduction, Cellular; Pulsatile Flow; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors; Treatment Outcome; Vascular Resistance | 2009 |
Large blood pressure variability and hypertensive cardiac remodeling--role of cardiac inflammation.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Humans; Hypertension; Macrophages; Myocarditis; Myocardium; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sympathectomy; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2009 |
A systematic review of angiotensin receptor blockers in preventing stroke.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Hypertension; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Risk Factors; Stroke; Treatment Outcome | 2009 |
Rational of the use of aliskiren in hypertension and beyond.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Europe; Fumarates; Germany; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Japan; Prevalence; Prorenin Receptor; Protein Precursors; Randomized Controlled Trials as Topic; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Time Factors; World Health Organization | 2009 |
Differences in pharmacology and their translation into differences in clinical efficacy--a comparison of the renin angiotensin blocking agents irbesartan and losartan.
Topics: Administration, Oral; Angiotensin II; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Blood Pressure; Diabetic Nephropathies; Health Care Costs; Humans; Hypertension; Irbesartan; Losartan; Tetrazoles; Treatment Outcome | 2010 |
Regulation of GPCR signaling in hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Disease Models, Animal; GTP-Binding Proteins; Humans; Hypertension; Prevalence; Receptor Protein-Tyrosine Kinases; Receptors, G-Protein-Coupled; Signal Transduction; United States; Vasoconstriction; Vasodilation | 2010 |
Endothelial dysfunction: a strategic target in the treatment of hypertension?
Topics: Angiotensin II; Animals; Antihypertensive Agents; Calcium; Dinucleoside Phosphates; Endothelin-1; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Humans; Hypertension; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Thromboxane; Vasoconstrictor Agents | 2010 |
Renal interactions of renin-angiotensin system, nitric oxide and superoxide anion: implications in the pathophysiology of salt-sensitivity and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Kidney; Nitric Oxide; Oxidative Stress; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Superoxides | 2009 |
Renal infiltration of immunocompetent cells: cause and effect of sodium-sensitive hypertension.
Topics: Adult; Angiotensin II; Animals; Autoimmunity; Disease Models, Animal; Heat-Shock Proteins; Humans; Hypertension; Immunocompetence; Inflammation; Kidney; Middle Aged; Nephritis; Oxidative Stress; Rats; Sodium; Sodium, Dietary | 2010 |
Endogenous ouabain in renal Na(+) handling and related diseases.
Topics: Adrenal Glands; Angiotensin II; Animals; Cell Proliferation; Diuretics; Drosophila; Epinephrine; Heart Failure; Homeostasis; Humans; Hypertension; Kidney; Myocytes, Cardiac; Myocytes, Smooth Muscle; Ouabain; Renal Insufficiency; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Vasoconstriction | 2010 |
The central role of the brain aldosterone-"ouabain" pathway in salt-sensitive hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Choroid Plexus; Ependyma; Epithelial Sodium Channels; Humans; Hypertension; Ion Transport; Kidney; Membrane Potentials; Neurons; Ouabain; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Sodium; Water-Electrolyte Balance | 2010 |
The ANG-(1-7)/ACE2/mas axis in the regulation of nephron function.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nephrons; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2010 |
[Intrarenal mechanisms of angiotensin II formation].
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Biomarkers; Humans; Hypertension; Kidney; Kidney Diseases; Peptidyl-Dipeptidase A; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Serine Proteases | 2010 |
[Role of angiotensin II on renal medullary circulation].
Topics: Angiotensin II; Animals; Biological Transport; Blood Pressure; Humans; Hypertension; Kidney Medulla; Kidney Tubules; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Receptors, Angiotensin; Regional Blood Flow; Renin-Angiotensin System; Sodium | 2010 |
Aliskiren versus ramipril in hypertension.
Topics: Aging; Amides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetic Angiopathies; Fumarates; Half-Life; Humans; Hypertension; Ramipril; Renin-Angiotensin System | 2010 |
Midkine regulation of the renin-angiotensin system.
Topics: Acetylcholinesterase; Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Central Nervous System; Cytokines; Fibroblast Growth Factors; Humans; Hypertension; Inflammation; Kidney Failure, Chronic; Lung; Mice; Midkine; Receptors, Fibroblast Growth Factor; Renin; Renin-Angiotensin System; Risk Factors | 2010 |
Oxidative stress and hypertension: current concepts.
Topics: Angiotensin II; Animals; Antioxidants; Cytokines; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hypertension; Inflammation; NADP; Nitric Oxide Synthase; Oxidative Stress; Reactive Oxygen Species; Risk Factors; Signal Transduction; Superoxides; Xanthine Oxidase | 2010 |
Vaccines in the management of hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Oligopeptides; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Treatment Outcome; Vaccines | 2010 |
[Hypertensiology 2010].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Dementia; Drug Resistance; Humans; Hypertension; Hypertension, Renal; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Reference Values; Vaccines | 2010 |
Secondary prevention of CAD with ACE inhibitors: a struggle between life and death of the endothelium.
Topics: Acute Coronary Syndrome; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Apoptosis; Atherosclerosis; Bradykinin; Cardiotonic Agents; Coronary Artery Disease; Disease Progression; Endothelial Cells; Endothelium, Vascular; Heart Failure; Humans; Hypertension; Peptidyl-Dipeptidase A; Perindopril; Plaque, Atherosclerotic; Randomized Controlled Trials as Topic; Secondary Prevention; Stem Cells | 2010 |
Hypertension management and microvascular insulin resistance in diabetes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Diabetes Mellitus, Type 2; Humans; Hypertension; Inflammation; Insulin Resistance; Microcirculation; Microvessels; Nitric Oxide Synthase Type III; Oxidative Stress; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction | 2010 |
Stimulation of reactive oxygen species and collagen synthesis by angiotensin II in cardiac fibroblasts.
Topics: Angiotensin II; Animals; Collagen; Fibroblasts; Fibrosis; Free Radical Scavengers; Heart Diseases; Humans; Hypertension; Myocardium; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Superoxides | 2012 |
Chymase as an important target for preventing complications of metabolic syndrome.
Topics: Angiotensin II; Animals; Atherosclerosis; Chymases; Diabetes Complications; Diabetic Retinopathy; Fatty Liver; Humans; Hypertension; Matrix Metalloproteinase 9; Metabolic Syndrome; Mice; Transforming Growth Factor beta | 2010 |
Valsartan-induced angioedema in a patient on angiotensin-converting enzyme inhibitor for years: case report and literature review.
Topics: Aged, 80 and over; Angioedema; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hypertension; Tetrazoles; Time Factors; Valine; Valsartan | 2012 |
The paradox of dopamine and angiotensin II-mediated Na(+), K(+)-ATPase regulation in renal proximal tubules.
Topics: Adenylyl Cyclases; Angiotensin II; Animals; Biological Transport; Dopamine; Humans; Hypertension; Kidney Tubules, Proximal; Membrane Proteins; PDZ Domains; Phosphorylation; Protein Isoforms; Protein Kinase C; Receptor Cross-Talk; Receptors, Angiotensin; Receptors, Dopamine; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Tight Junction Proteins | 2010 |
ACE2: more of Ang-(1-7) or less Ang II?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2011 |
Endothelial damage and regeneration: the role of the renin-angiotensin-aldosterone system.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Endothelium, Vascular; Humans; Hypertension; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Risk Factors; Stem Cells | 2011 |
Angiotensin II, tissue factor and the thrombotic paradox of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Endothelium, Vascular; Humans; Hypertension; Renin; Renin-Angiotensin System; Risk Factors; Thromboplastin; Thrombosis | 2010 |
Experience with angiotensin II antagonists in hypertensive patients.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; Renin-Angiotensin System | 1996 |
Brain angiotensin AT1 receptors as specific regulators of cardiovascular reactivity to acute psychoemotional stress.
Topics: Angiotensin II; Animals; Appetitive Behavior; Blood Pressure; Brain; Cardiovascular System; Hypertension; Mice; Rats; Receptor, Angiotensin, Type 1; Stress, Psychological | 2011 |
The central nervous system and inflammation in hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; Brain; Humans; Hypertension; Immune System; Inflammation; Lymphocyte Activation; Renin-Angiotensin System; T-Lymphocytes | 2011 |
Oxidative stress and endothelial dysfunction in cerebrovascular disease.
Topics: Alzheimer Disease; Amidohydrolases; Angiotensin II; Animals; Brain Ischemia; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Mitochondria; Nitric Oxide; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Reperfusion Injury; Stroke; Subarachnoid Hemorrhage; Superoxide Dismutase | 2011 |
Neural mechanisms of angiotensin II-salt hypertension: implications for therapies targeting neural control of the splanchnic circulation.
Topics: Angiotensin II; Humans; Hypertension; Risk Factors; Sodium, Dietary; Splanchnic Circulation; Splanchnic Nerves; Sympathetic Nervous System | 2011 |
Mineralocorticoid actions in the brain and hypertension.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Brain; Cerebrospinal Fluid; Cytochrome P-450 CYP11B2; Epithelial Sodium Channels; Humans; Hypertension; Mineralocorticoids; Ouabain; Pressoreceptors; Renin-Angiotensin System | 2011 |
Intrarenal angiotensin II and its contribution to the genesis of chronic hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Chronic Disease; Humans; Hypertension; Kidney; Kidney Tubules, Collecting; Prorenin Receptor; Receptors, Cell Surface; Renin | 2011 |
Angiotensin peptides and central autonomic regulation.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Brain; Humans; Hypertension; MAP Kinase Signaling System; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol 3-Kinases | 2011 |
Hypertension in kidney transplant recipients.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcineurin Inhibitors; Calcium Channel Blockers; Cardiovascular Diseases; Cyclosporine; Diuretics; Glucocorticoids; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Life Style; Renal Artery Obstruction; Vascular Resistance | 2011 |
Coupling between respiratory and sympathetic activities as a novel mechanism underpinning neurogenic hypertension.
Topics: Angiotensin II; Chronic Disease; Humans; Hypertension; Hypoxia; Pressoreceptors; Respiratory System; Sympathetic Nervous System; Time Factors | 2011 |
Angiotensin II and the vascular phenotype in hypertension.
Topics: Angiotensin II; Humans; Hypertension; Muscle, Smooth, Vascular; Phenotype; Renin-Angiotensin System; Vascular Diseases | 2011 |
Do genetic variants of the Renin-Angiotensin system predict blood pressure response to Renin-Angiotensin system-blocking drugs?: a systematic review of pharmacogenomics in the Renin-Angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Genetic Variation; Humans; Hypertension; Peptidyl-Dipeptidase A; Pharmacogenetics; Polymorphism, Genetic; Renin-Angiotensin System | 2011 |
Role of ACE2 in diastolic and systolic heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Heart Failure; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Signal Transduction | 2012 |
Angiotensin-II-induced reactive oxygen species along the SFO-PVN-RVLM pathway: implications in neurogenic hypertension.
Topics: Angiotensin II; Humans; Hypertension; Medulla Oblongata; Neurons; Paraventricular Hypothalamic Nucleus; Reactive Oxygen Species; Subfornical Organ | 2011 |
Cross talk between mitochondria and NADPH oxidases.
Topics: Aging; Angiotensin II; Animals; Antioxidants; Atherosclerosis; Diabetes Mellitus; Humans; Hypertension; Mice; Mitochondria; NADPH Oxidases; Neurodegenerative Diseases; Nitric Oxide Synthase Type III; Organophosphorus Compounds; Oxidation-Reduction; Oxidative Stress; Piperidines; Rabbits; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Xanthine Oxidase | 2011 |
Renal oxidative stress, oxygenation, and hypertension.
Topics: Angiotensin II; Animals; Antioxidants; Disease Progression; Fibrosis; Humans; Hypertension; Hypoxia; Kidney; Kidney Diseases; Oxidative Stress; Oxygen; Oxygen Consumption; Reactive Oxygen Species | 2011 |
Therapeutic vaccines for chronic diseases: successes and technical challenges.
Topics: Angiotensin II; Animals; Antibodies; Antibody Formation; Antihypertensive Agents; Chronic Disease; Diabetes Mellitus, Type 2; Humans; Hypertension; Interleukin-1beta; Mice; Nicotine; Risk Factors; Smoking; Smoking Cessation; Vaccination; Vaccines; Vaccines, Virus-Like Particle | 2011 |
Emerging drugs which target the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Clinical Trials as Topic; Drug Design; Drugs, Investigational; Humans; Hypertension; Renin-Angiotensin System; Treatment Outcome | 2011 |
Hypertensive effects of the iv administration of picomoles of ouabain.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Cardiotonic Agents; Central Nervous System; Humans; Hypertension; Injections, Intravenous; Norepinephrine; Ouabain; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase | 2011 |
The complex interplay between cyclooxygenase-2 and angiotensin II in regulating kidney function.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Hypertension; Kidney; Kidney Diseases; Renin-Angiotensin System; Signal Transduction | 2012 |
Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model.
Topics: Angiotensin II; Animals; Cell Nucleus; Cytoplasm; Disease Models, Animal; Hypertension; In Vitro Techniques; Mice; Mice, Transgenic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2012 |
Reno-protective effects of renin-angiotensin system blockade in type 2 diabetic patients: a systematic review and network meta-analysis.
Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension; Kidney Failure, Chronic; Middle Aged; Randomized Controlled Trials as Topic; Renin-Angiotensin System | 2012 |
Inflammation in hypertension: current therapeutic approaches.
Topics: Adipose Tissue; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Cell Adhesion Molecules; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Endothelium, Vascular; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Inflammation; Inflammation Mediators; NF-kappa B; Reactive Oxygen Species | 2011 |
Critical review of cancer risk associated with angiotensin receptor blocker therapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Clinical Trials as Topic; Humans; Hypertension; Meta-Analysis as Topic; Neoplasms; Neovascularization, Pathologic; Obesity; Receptors, Angiotensin; Risk Factors | 2011 |
[Mechanisms responsible for the renoprotective effects of renin-angiotensin inhibitors].
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Humans; Hypertension; Kidney; Mineralocorticoid Receptor Antagonists; Rats; Receptors, Mineralocorticoid; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2012 |
[In vitro and in vivo pharmacological profiles of a novel angiotensin type 1-receptor blocker, azilsartan].
Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Hypertension; Insulin Resistance; Obesity; Oxadiazoles | 2012 |
Sex differences in hypertension: contribution of the renin-angiotensin system.
Topics: Angiotensin II; Estrogens; Female; Hemodynamics; Humans; Hypertension; Male; Renin; Renin-Angiotensin System; Sex Characteristics; Sex Factors; Testosterone | 2012 |
The pharmacokinetics and pharmacodynamics of valsartan in the post-myocardial infarction population.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan | 2012 |
Renal dopamine and angiotensin II receptor signaling in age-related hypertension.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Dopamine; Humans; Hypertension; Kidney; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Dopamine D1; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2013 |
Impaired pressure natriuresis is associated with interstitial inflammation in salt-sensitive hypertension.
Topics: Angiotensin II; Humans; Hypertension; Kidney Tubules; Microvessels; Natriuresis; Nephritis, Interstitial; Oxidative Stress; Sodium Chloride, Dietary | 2013 |
Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephron.
Topics: Aldosterone; Angiotensin II; Animals; Epithelial Sodium Channels; Humans; Hyperkalemia; Hypertension; Hypovolemia; Kidney Tubules, Collecting; Kidney Tubules, Distal; Potassium; Potassium Channels, Inwardly Rectifying; Signal Transduction; Sodium; Sodium Chloride Symporters | 2013 |
Vascular actions of aldosterone.
Topics: Adipocytes; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Vessels; Cardiovascular Diseases; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Hypertrophy; Metabolic Syndrome; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Muscle, Smooth, Vascular; Oxidative Stress; Receptor, Endothelin A; Receptors, Mineralocorticoid; Renin-Angiotensin System; Signal Transduction; Sodium; Vasculitis; Vasoconstriction | 2013 |
Angiotensinergic innervation of the kidney: present knowledge and its significance.
Topics: Angiotensin II; Animals; Autonomic Nervous System; Endothelium, Vascular; Humans; Hypertension; Immunohistochemistry; Kidney; Neuroeffector Junction; Neurons; Neuropeptides; Synaptic Transmission | 2013 |
Sympathetic nervous system and hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Carotid Body; Disease Models, Animal; Humans; Hypertension; Kidney; Obesity; Rabbits; Rats; Sympathetic Nervous System; Vasoconstrictor Agents | 2013 |
Are clinical endpoint benefits of angiotensin converting enzyme inhibitors independent of their blood pressure effects?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Blood Pressure; Cardiovascular System; Diabetes Mellitus; Diabetic Nephropathies; Endothelium, Vascular; Humans; Hypertension; Kidney Diseases; Receptors, Angiotensin; Renin-Angiotensin System | 2002 |
AT(1)-receptor blockers: differences that matter.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Binding, Competitive; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 2002 |
Targeting the renin-angiotensin system in patients with renal disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Contraindications; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypertension; Kidney Diseases; Proteinuria; Risk Factors; Vasoconstrictor Agents | 2002 |
Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases.
Topics: Angiotensin I; Angiotensin II; Arteriosclerosis; Cardiomegaly; Cardiovascular Diseases; Chymases; Heart Diseases; Heart Failure; Humans; Hypertension; Peptidyl-Dipeptidase A; Serine Endopeptidases | 2002 |
Molecular biology of blood pressure regulatory genes.
Topics: Angiotensin II; Animals; Blood Pressure; Genes, Regulator; Genetic Markers; Hypertension; Molecular Biology; Prognosis; Rats; Receptors, Angiotensin; Receptors, Prostaglandin E; Receptors, Thromboxane; Sensitivity and Specificity; Vascular Resistance | 2002 |
[Prevention and treatment of congestive heart failure in diabetic patients].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Carbazoles; Cardiotonic Agents; Carvedilol; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Male; Meta-Analysis as Topic; Metoprolol; Prognosis; Propanolamines; Risk Factors; Time Factors | 2002 |
Does the angiotensin II receptor antagonist losartan improve cognitive function?
Topics: Aged; Aged, 80 and over; Aging; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Clinical Trials as Topic; Cognition Disorders; Humans; Hypertension; Losartan | 2002 |
Compliance and persistence with newer antihypertensive agents.
Topics: Angiotensin II; Antihypertensive Agents; Clinical Trials as Topic; Drug Tolerance; Humans; Hypertension; Patient Compliance; Practice Guidelines as Topic; United States | 2002 |
Local cardiac renin-angiotensin system: hypertension and cardiac failure.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Heart; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Myocardium; Organ Specificity; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Vascular Resistance; Ventricular Remodeling | 2002 |
Role of the local renin-angiotensin system in cardiac damage: a minireview focussing on transgenic animal models.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Cardiomegaly; Fibrosis; Heart; Hypertension; Mice; Mice, Knockout; Mice, Transgenic; Models, Biological; Myocardial Infarction; Myocardium; Organ Specificity; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Stress, Mechanical; Ventricular Remodeling | 2002 |
Angiotensin AT-1 receptor antagonism: complementary or alternative to ACE inhibition in cardiovascular and renal disease?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Cough; Diabetes Complications; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Diseases; Myocardial Infarction; Receptor, Angiotensin, Type 1 | 2002 |
[The effect of angiotensin-converting enzyme inhibitors on the progression of chronic renal failure].
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Clinical Trials as Topic; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Endothelins; Hemodynamics; Humans; Hypertension; Indoles; Irbesartan; Kidney; Kidney Failure, Chronic; Proteinuria; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Verapamil | 2002 |
Treatment of hypertension from volume to vasoconstriction: The ACE up your sleeve.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diuretics; Humans; Hypertension | 2002 |
[New findings in hypertension treatment: role of angiotensin II antagonists].
Topics: Angiotensin II; Humans; Hypertension | 1999 |
Olmesartan medoxomil: the seventh angiotensin receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hypertension; Imidazoles; Olmesartan Medoxomil; Prescription Fees; Receptors, Angiotensin; Tetrazoles | 2003 |
Regulation of myocardial fibrillar collagen by angiotensin II. A role in hypertensive heart disease?
Topics: Angiotensin II; Antihypertensive Agents; Fibrillar Collagens; Fibrosis; Humans; Hypertension; Myocardium | 2002 |
Lyon genetically hypertensive rats: an animal model of "low renin hypertension".
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney; Models, Animal; Rats; Regional Blood Flow; Renin; Renin-Angiotensin System | 2003 |
Nephrin: a pivotal molecule in proteinuria influenced by angiotensin II.
Topics: Albuminuria; Angiotensin II; Animals; Diabetic Angiopathies; Humans; Hypertension; Membrane Proteins; Proteins; Proteinuria | 2003 |
Inhibitors of Na+/Mg2+ exchange activity attenuate the development of hypertension in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Antiporters; Hypertension; Rats; Vasoconstrictor Agents | 2003 |
Angiotensin-converting enzyme inhibitors for stroke prevention: is there HOPE for PROGRESS After LIFE?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Blood Pressure; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Life Style; Practice Guidelines as Topic; Ramipril; Risk; Risk Factors; Stroke; Telmisartan | 2003 |
RGS2: a "turn-off" in hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Mice; Mice, Knockout; Models, Biological; RGS Proteins; Signal Transduction; Vasoconstriction | 2003 |
Recent advances in intracellular signalling in hypertension.
Topics: Angiotensin II; Female; Humans; Hypertension; Ion Transport; Male; Muscle, Smooth, Vascular; Oxidation-Reduction; Protein-Tyrosine Kinases; Reactive Oxygen Species; Receptors, Angiotensin; Sensitivity and Specificity; Signal Transduction | 2003 |
Vascular inflammation: a role in vascular disease in hypertension?
Topics: Angiotensin II; Arteriosclerosis; Endothelins; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation Mediators; Male; Nitric Oxide; Predictive Value of Tests; Prognosis; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Vascular Diseases; Vascular Endothelial Growth Factor A | 2003 |
Dopamine and the kidney: a role in hypertension?
Topics: Angiotensin II; Animals; Disease Models, Animal; Disease Progression; Dopamine; Female; Humans; Hypertension; Kidney Diseases; Male; Mice; Polymorphism, Genetic; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Dopamine; Renin-Angiotensin System; Sensitivity and Specificity; Sodium Chloride | 2003 |
Role of oxidative stress in angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Arachidonic Acid; Blood Pressure; Endothelins; Hypertension; Kidney; Nitric Oxide; Oxidative Stress | 2003 |
Intrarenal angiotensin II and hypertension.
Topics: Angiotensin II; Animals; Humans; Hypertension; Kidney; Kidney Tubules; Nephrons; Receptors, Angiotensin | 2003 |
The role of angiotensin II-stimulated renal tubular transport in hypertension.
Topics: Angiotensin II; Animals; Biological Transport, Active; Humans; Hypertension; Kidney Tubules; Receptors, Angiotensin; Signal Transduction; Sodium | 2003 |
The role of angiotensin II in regulating vascular structural and functional changes in hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Arteries; Cell Division; Fibrosis; Humans; Hypertension; Inflammation; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Oxidation-Reduction; Protein Serine-Threonine Kinases; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vascular Resistance; Vasomotor System | 2003 |
The choice of antihypertensive drugs in patients with diabetes: angiotensin II and beyond.
Topics: Angiotensin II; Antihypertensive Agents; Diabetic Angiopathies; Humans; Hypertension; Renin-Angiotensin System | 2002 |
An update on 'progression promoters' in renal diseases.
Topics: Angiotensin II; Disease Progression; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Risk Factors | 2003 |
Treatment of hypertension in type 2 diabetes mellitus: blood pressure goals, choice of agents, and setting priorities in diabetes care.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diuretics; Evidence-Based Medicine; Humans; Hypertension; Randomized Controlled Trials as Topic; Sodium Chloride Symporter Inhibitors | 2003 |
The adipose-tissue renin-angiotensin-aldosterone system: role in the metabolic syndrome?
Topics: Adipocytes; Adipose Tissue, Brown; Angiotensin II; Angiotensinogen; Animals; Humans; Hypertension; Insulin Resistance; Metabolic Syndrome; Mice; Obesity; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Thermogenesis | 2003 |
Obesity-associated activation of angiotensin and endothelin in the cardiovascular system.
Topics: Adipocytes; Adiponectin; Angiotensin II; Animals; Endothelin-1; Endothelium, Vascular; Hormones, Ectopic; Humans; Hypertension; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Kidney; Leptin; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Renin-Angiotensin System; Resistin | 2003 |
Brainstem mechanisms of hypertension: role of the rostral ventrolateral medulla.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Humans; Hypertension; Kynurenic Acid; Medulla Oblongata; Muscarinic Antagonists; Neurons; Signal Transduction; Sympathetic Nervous System | 2003 |
Contribution of salt intake to insulin resistance associated with hypertension.
Topics: Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Humans; Hypertension; Insulin; Insulin Resistance; Oxidative Stress; Potassium, Dietary; Rats; Rats, Inbred Dahl; Signal Transduction; Sodium Chloride, Dietary | 2003 |
Brain renin-angiotensin system dysfunction in hypertension: recent advances and perspectives.
Topics: Angiotensin II; Animals; Baroreflex; Humans; Hypertension; Medulla Oblongata; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System | 2003 |
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2 | 2003 |
Debate: angiotensin-converting enzyme inhibitors versus angiotensin II receptor blockers--a gap in evidence-based medicine.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Evidence-Based Medicine; Humans; Hypertension; Risk Factors | 2003 |
Interactions between the renin-angiotensin system and dyslipidemia: relevance in the therapy of hypertension and coronary heart disease.
Topics: Angiotensin II; Animals; Cholesterol; Coronary Artery Disease; Endothelium, Vascular; Humans; Hyperlipidemias; Hypertension; Lipoproteins, LDL; Oxidation-Reduction; Reactive Oxygen Species; Renin-Angiotensin System | 2003 |
Olmesartan medoxomil: an angiotensin II-receptor blocker.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Drug Interactions; Humans; Hypertension; Imidazoles; Olmesartan Medoxomil; Tetrazoles | 2003 |
Association between transforming growth factor-beta and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Models, Animal; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
[Hemodynamic factors].
Topics: Angiotensin II; Animals; Diabetes Mellitus; Disease Models, Animal; Humans; Hypertension; Insulin; Insulin Resistance; Oxidative Stress; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Signal Transduction | 2003 |
[Oxidative stress].
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Humans; Hypertension; Insulin Resistance; Lipid Metabolism; Nitric Oxide; Oxidants; Oxidative Stress; Reactive Oxygen Species | 2003 |
Angiotensin II, the immune system and renal diseases: another road for RAS?
Topics: Angiotensin II; Animals; Hypertension; Kidney Diseases; Killer Cells, Natural; Lymphokines; Renin-Angiotensin System | 2003 |
Application of a chymase inhibitor, NK3201, for prevention of vascular proliferation.
Topics: Acetamides; Angioplasty, Balloon; Angiotensin II; Animals; Cell Division; Chymases; Endothelium, Vascular; Graft Occlusion, Vascular; Humans; Hypertension; Protease Inhibitors; Pyrimidines; Serine Endopeptidases; Vascular Diseases | 2003 |
Angiotensin II and endothelin induce inflammation and thereby promote hypertension-induced end-organ damage.
Topics: Angiotensin II; Animals; Endothelin-1; Gene Expression Regulation; Humans; Hypertension; NF-kappa B; Vasculitis | 2003 |
Multiple actions of angiotensin II in hypertension: benefits of AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Fibrinolysis; Humans; Hypertension; Inflammation; Inflammation Mediators; Oxidative Stress; Reactive Oxygen Species; Tetrazoles | 2003 |
[New perspectives of the use of angiotensin II receptor blocker].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Diabetes Mellitus; Humans; Hypertension; Hypertrophy, Left Ventricular; Hyperuricemia; Losartan; Receptors, Angiotensin | 2003 |
Cardiomyocyte apoptosis in hypertensive cardiomyopathy.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Apoptosis; Arrhythmias, Cardiac; Humans; Hypertension; MAP Kinase Signaling System; Models, Animal; Myocardial Ischemia; Myocytes, Cardiac; Oxidative Stress; Ventricular Remodeling | 2003 |
Pathogenesis of diabetic retinopathy and the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diabetic Retinopathy; Disease Progression; Humans; Hyperglycemia; Hypertension; Macular Degeneration; Receptors, Angiotensin; Renin-Angiotensin System; Risk Factors; Vascular Endothelial Growth Factors | 2003 |
Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Humans; Hypertension; Oxidation-Reduction; Signal Transduction | 2003 |
[Cerebrovascular sequelae of hypertension].
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alzheimer Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Dementia, Vascular; Diuretics; Humans; Hypertension; Risk Factors; Stroke; Treatment Outcome | 2003 |
Angiotensin II antagonists in the treatment of hypertension-effective and efficient?
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Kidney Failure, Chronic; Stroke; Treatment Outcome | 2003 |
Interactions between the sympathetic nervous system and the kidneys in arterial hypertension.
Topics: Angiotensin II; Animals; Humans; Hypertension; Hypertension, Renovascular; Kidney; Kidney Failure, Chronic; Obesity; Rats; Rats, Inbred SHR; Stress, Psychological; Sympathetic Nervous System | 2004 |
[Angiotensin II in organ organopathy].
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertension | 2004 |
Insulin and insulin resistance: impact on blood pressure and cardiovascular disease.
Topics: Angiotensin II; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin; Insulin Resistance; Obesity; Risk Factors | 2004 |
Fibrosis in hypertensive heart disease: role of the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Collagen; Fibrosis; Humans; Hypertension; Renin-Angiotensin System | 2004 |
Conformation and bioactivity. Design and discovery of novel antihypertensive drugs.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Design; Humans; Hypertension; Losartan; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Mimicry; Peptides; Structure-Activity Relationship | 2004 |
On the structural basis of the hypertensive properties of angiotensin II: a solved mystery or a controversial issue?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Humans; Hypertension; Molecular Structure; Protein Conformation; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; Vasoconstrictor Agents | 2004 |
[IgA nephropathy].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biopsy; Diagnosis, Differential; Disease Progression; Glomerulonephritis, IGA; Hematuria; Humans; Hypertension; Immunosuppressive Agents; Incidence; Kidney; Kidney Failure, Chronic; Prognosis; Proteinuria; Risk Factors; Time Factors | 2003 |
Oxidative stress in hypertension and chronic kidney disease: role of angiotensin II.
Topics: Angiotensin II; Animals; Cells, Cultured; Chronic Disease; Disease Models, Animal; Humans; Hypertension; Infusion Pumps; Kidney Diseases; Oxidative Stress; Sodium Chloride, Dietary | 2004 |
Insulin resistance and hypertension.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress | 2004 |
Angiotensin in atherosclerosis.
Topics: Angiotensin II; Arteriosclerosis; Diabetes Mellitus; Disease Progression; Estrogens; Humans; Hyperlipidemias; Hypertension; Inflammation; Insulin Resistance; Risk Factors | 2004 |
Monocyte chemoattractant protein-1: a key mediator of angiotensin II-induced target organ damage in hypertensive heart disease?
Topics: Angiotensin II; Cardiomyopathies; Chemokine CCL2; Humans; Hypertension | 2004 |
Evolving role of aldosterone blockers alone and in combination with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in hypertension management: a review of mechanistic and clinical data.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Eplerenone; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Spironolactone | 2004 |
Angiotensin II and the hypertensive heart: a role for the AT2 receptor?
Topics: Angiotensin II; Animals; Humans; Hypertension; Hypertrophy, Left Ventricular; Receptor, Angiotensin, Type 2 | 2004 |
Irbesartan: a review of its use in hypertension and in the management of diabetic nephropathy.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension; Irbesartan; Randomized Controlled Trials as Topic; Tetrazoles | 2004 |
Pathogenesis of structural vascular changes in hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Obesity; Sodium Chloride, Dietary; Vascular Resistance | 2004 |
[The bioactivity of angiotensin II and the effects of related Chinese Herbs].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Drugs, Chinese Herbal; Heart Failure; Humans; Hypertension; Myocardial Reperfusion Injury; Plants, Medicinal; Receptor, Angiotensin, Type 2 | 2003 |
[Vascular remodeling].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Vessels; Humans; Hypertension; Oxidative Stress; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2004 |
[Mechanism of vascular endothelial dysfunction induced by hypertension].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arteriosclerosis; Endothelium, Vascular; Humans; Hypertension; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Risk Factors | 2004 |
[Oxidative stress and vascular dysfunction in hypertension].
Topics: Angiotensin II; Animals; Endothelium, Vascular; Humans; Hypertension; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Phosphoproteins; Signal Transduction; Superoxide Dismutase | 2004 |
[Involvement of angiotensin II in pathogenesis of hypertension and target organ damage].
Topics: Angioplasty, Balloon, Coronary; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Cardiomegaly; Clinical Trials as Topic; Coronary Restenosis; Humans; Hypertension; Hypertension, Renal; Insulin Resistance; Losartan; Ramipril; Receptor, Angiotensin, Type 1 | 2004 |
[Involvement of HGF in the pathogenesis of hypertension and hypertensive target-organ damage].
Topics: Angiotensin II; Animals; Apoptosis; Arteriosclerosis; Autocrine Communication; Down-Regulation; Endothelium, Vascular; Hepatocyte Growth Factor; Humans; Hypertension; Kidney Tubules; Paracrine Communication; Transforming Growth Factor beta | 2004 |
[NO and hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arginine; Arteriosclerosis; Biopterins; C-Reactive Protein; Endothelium, Vascular; Humans; Hypertension; Mutation; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Perindopril; Reactive Oxygen Species; Vasodilation | 2004 |
[Hypertension in patients with cardiac hypertrophy].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetes Complications; Diabetes Mellitus; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors | 2004 |
[Organ protection by angiotensin II receptor blockers].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cognition Disorders; Heart Failure; Humans; Hypertension; Kidney Diseases; Losartan; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Proteins; Proteinuria; Randomized Controlled Trials as Topic; Stroke; Tetrazoles | 2004 |
Combined blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists.
Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Agents; Diabetic Nephropathies; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Proteinuria; Rats; Renin-Angiotensin System; Ventricular Dysfunction, Left | 2004 |
Assessment of the optimal daily dose of valsartan in patients with hypertension, heart failure, or both.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2004 |
Prevention and treatment of stroke in patients with hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Anticoagulants; Antihypertensive Agents; Costs and Cost Analysis; Humans; Hypertension; Losartan; Quality of Life; Randomized Controlled Trials as Topic; Risk Factors; Stroke | 2004 |
Involvement of renal sympathetic nerve in pathogenesis of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Brain; Humans; Hypertension; Kidney; Pressoreceptors; Reflex; Sodium; Sympathetic Nervous System | 2004 |
Renal renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Kidney Tubules; Nitric Oxide; Renin-Angiotensin System | 2004 |
[Hemodialysis-associated hypertension; pathophysiology and therapy].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Erythropoietin; Humans; Hypertension; Kidney Failure, Chronic; Renal Circulation; Renal Dialysis; Renin-Angiotensin System; Sleep Apnea Syndromes; Sympathetic Nervous System; Vascular Resistance | 2004 |
Nitric oxide, angiotensin II, and hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Prognosis; Renal Circulation; Renin-Angiotensin System; Risk Factors | 2004 |
Lead-induced hypertension: role of oxidative stress.
Topics: Angiotensin II; Animals; Confounding Factors, Epidemiologic; Environmental Exposure; Guanylate Cyclase; Humans; Hypertension; Lead; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2004 |
How important is optimal blood pressure control?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Humans; Hypertension; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Risk Factors | 2004 |
The role of LOX-1, a novel lectin-like receptor for oxidized low density lipoprotein, in atherosclerosis.
Topics: Angiotensin II; Atherosclerosis; Biomarkers; Coronary Artery Disease; Diabetes Mellitus; Endothelial Cells; Gene Expression Regulation; Humans; Hypertension; Lipoproteins, LDL; Myocardial Ischemia; Oxidative Stress; Predictive Value of Tests; Receptors, Oxidized LDL; Risk Factors; Scavenger Receptors, Class E; Sensitivity and Specificity; Severity of Illness Index; Signal Transduction | 2004 |
A novel therapeutic strategy against vascular disorders with chymase inhibitor.
Topics: Angioplasty, Balloon; Angiotensin II; Animals; Blood Vessels; Chymases; Enzyme Inhibitors; Graft Occlusion, Vascular; Humans; Hypertension; Serine Endopeptidases; Vascular Diseases | 2003 |
Treatment of systolic hypertension: spotlight on recent studies with angiotensin II antagonists.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Losartan; Patient Compliance; Practice Guidelines as Topic; Stroke; Systole | 2005 |
Provision of cardiovascular protection by ACE inhibitors: a review of recent trials.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Cardiovascular Diseases; Clinical Trials as Topic; Heart Arrest; Humans; Hypertension; Myocardial Infarction; Oxidative Stress; Risk Factors; Vasodilation | 2004 |
[Renin-angiotensin-aldosterone system and natriuretic peptide system--reference to cardiovascular diseases].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiovascular Diseases; Drug Design; Heart Failure; Humans; Hypertension; Kidney Tubules, Distal; Natriuresis; Natriuretic Peptides; Renin-Angiotensin System; Sodium; Sodium, Dietary; Water-Electrolyte Balance | 2004 |
[Mitogenic action of endothelin on fibroblasts].
Topics: Angiotensin II; Animals; Cell Division; Collagen; Endothelin-1; Extracellular Matrix; Fibroblast Growth Factor 2; Fibroblasts; Glomerulosclerosis, Focal Segmental; Humans; Hypertension; Liver Cirrhosis; Myoblasts, Cardiac; Myocardial Infarction; Pulmonary Fibrosis; Receptors, Endothelin; Transforming Growth Factor beta; Ventricular Remodeling | 2004 |
[Modulation of renin-angiotensin system for vascular protection in hypertensive patients and in patients with diabetic nephropathy].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiomegaly; Coronary Artery Disease; Diabetic Nephropathies; Humans; Hypertension; Renin | 2004 |
The role of angiotensin antagonism in stroke prevention in patients with hypertension: focus on losartan.
Topics: Angiotensin II; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Losartan; Stroke | 2004 |
[Tissue consequence of renin-angiotensin system activation].
Topics: Angiotensin II; Arteriosclerosis; Blood Coagulation; Calcium; Humans; Hypertension; Inflammation; Receptors, Cell Surface; Renin-Angiotensin System; Signal Transduction; Vacuolar Proton-Translocating ATPases; Vasoconstrictor Agents | 2004 |
Malfunction of vascular control in lifestyle-related diseases: oxidative stress of angiotensin II-induced hypertension: mitogen-activated protein kinases and blood pressure regulation.
Topics: Angiotensin II; Animals; Blood Pressure; Enzyme Activation; Humans; Hypertension; Mitogen-Activated Protein Kinases; NADPH Oxidases; Oxidative Stress; Rats; Vasoconstriction | 2004 |
Left ventricular hypertrophy and angiotensin II receptor blocking agents.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Antihypertensive Agents; Cardiotonic Agents; Clinical Trials as Topic; Humans; Hypertension; Hypertrophy, Left Ventricular; Models, Animal; Myocardium; Reactive Oxygen Species | 2005 |
Nitric oxide, angiotensin II, and reactive oxygen species in hypertension and atherogenesis.
Topics: Angiotensin II; Antihypertensive Agents; Arteriosclerosis; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Reactive Oxygen Species | 2005 |
Molecular and cellular mechanisms in vascular injury in hypertension: role of angiotensin II.
Topics: Angiotensin II; Humans; Hypertension; Inflammation; Vascular Diseases | 2005 |
The future of angiotensin II inhibition in cardiovascular medicine.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Drug Therapy, Combination; Heart Failure; Humans; Hypertension; Kidney Diseases; Myocardial Infarction; Protease Inhibitors; Renin; Risk Factors | 2005 |
Endothelin, angiotensin, and oxidative stress in hypertension.
Topics: Angiotensin II; Animals; Blood Vessels; Endothelin-1; Humans; Hypertension; Oxidative Stress; Receptor, Endothelin B | 2005 |
Hypertension and atherosclerosis: clinical implications from the ALLHAT Trial.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Coronary Artery Disease; Diuretics; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypertension; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Sodium Chloride Symporter Inhibitors; Sulfonamides; Survival Rate; Treatment Failure | 2005 |
[Renin-angiotensin system blockers and organ protection].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Renin-Angiotensin System | 2005 |
Anti-stress and anti-anxiety effects of centrally acting angiotensin II AT1 receptor antagonists.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Anti-Anxiety Agents; Brain; Humans; Hypertension; Receptor, Angiotensin, Type 1; Stress, Psychological | 2005 |
The pathophysiologic basis for blocking the renin-angiotensin system in hypertensive patients with renal disease.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetic Nephropathies; Glucose; Hemodynamics; Homeostasis; Humans; Hypertension; Kidney Diseases; Nitric Oxide; Renin-Angiotensin System | 2005 |
[Angiotensin II receptor blockers--evidence along the cardiovascular continuum].
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dogs; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardial Infarction; Placebos; Rabbits; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors; Stroke; Tetrazoles; Time Factors | 2005 |
Intracellular mechanisms involved in vascular remodelling of resistance arteries in hypertension: role of angiotensin II.
Topics: Angiotensin II; Animals; Arteries; Humans; Hypertension; Oxygen Consumption; Vascular Resistance | 2005 |
Six truisms concerning ACE and the renin-angiotensin system educed from the genetic analysis of mice.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney Diseases; Male; Mice; Mice, Knockout; Myocardium; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Testis | 2005 |
Endothelial dysfunction: its role in hypertensive coronary disease.
Topics: Angiotensin II; Antihypertensive Agents; Arginine; Coronary Disease; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Nitric Oxide; Oxidants | 2005 |
The role of angiotensin II in hypertension and end-organ damage.
Topics: Angiotensin II; Animals; Arteriosclerosis; Coronary Disease; Diabetes Complications; Humans; Hypertension; Kidney Diseases | 2000 |
[The Diabetic Retinopathy Candesartan Trials (DIRECT) programme].
Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Retinopathy; Humans; Hypertension; Randomized Controlled Trials as Topic; Receptors, Vascular Endothelial Growth Factor; Renin-Angiotensin System; Retina; Risk Factors; Tetrazoles; Vascular Endothelial Growth Factor A | 2005 |
Saga of renin-angiotensin system and calcium channels in hypertensive diabetics: does it have a therapeutic edge?
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcium Channel Blockers; Calcium Channels; Cardiovascular Diseases; Diabetes Complications; Drug Therapy, Combination; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2005 |
Oxidative-nitrosative stress in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Membrane Transport Proteins; NADPH Oxidases; Phosphoproteins; Poly(ADP-ribose) Polymerases; Polymorphism, Genetic; Reactive Oxygen Species; Signal Transduction | 2005 |
[Vasoprotective effects of statins and angiotensin II blockers in atherothrombosis].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticholesteremic Agents; Antihypertensive Agents; Arteriosclerosis; Cardiovascular Diseases; Cholesterol; Cyclooxygenase Inhibitors; Endothelium, Vascular; Haplorhini; Humans; Hypertension; Hypolipidemic Agents; Lipid Metabolism; Randomized Controlled Trials as Topic; Renin-Angiotensin System | 2005 |
[Angiotensin I, angiotensin II, angiotensin III].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Biomarkers; Chromatography, High Pressure Liquid; Cushing Syndrome; Diagnosis, Differential; Diagnostic Techniques, Endocrine; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Myocardial Infarction; Radioimmunoassay; Reference Values; Renin-Angiotensin System; Specimen Handling; Water-Electrolyte Imbalance | 2005 |
Angiotensin and diabetic retinopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Diabetic Retinopathy; Humans; Hypertension; Neovascularization, Pathologic; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Retina | 2006 |
The role of the kidneys in hypertension.
Topics: Angiotensin II; Blood Pressure; Hemodynamics; Humans; Hypertension; Kidney; Natriuresis; Renin-Angiotensin System; Sodium | 2005 |
Role of angiotensin II in the evolution of diastolic heart failure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Mineralocorticoid Receptor Antagonists; Prognosis; Renal Insufficiency; Renin-Angiotensin System; Treatment Outcome | 2005 |
Increased expression and function of vascular alpha1D-adrenoceptors may mediate the prohypertensive effects of angiotensin II.
Topics: Angiotensin II; Animals; Blood Vessels; Hypertension; Muscle, Smooth, Vascular; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Renin-Angiotensin System; Signal Transduction | 2005 |
Molecular mechanisms and therapeutic strategies of chronic renal injury: role of rho-kinase in the development of renal injury.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; Fibrosis; Glomerulosclerosis, Focal Segmental; Hypertension; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Microcirculation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents | 2006 |
Molecular mechanisms and therapeutic strategies of chronic renal injury: physiological role of angiotensin II-induced oxidative stress in renal medulla.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aortic Valve Stenosis; Blood Pressure; Diffusion; Disease Models, Animal; Humans; Hypertension; Kidney Diseases; Kidney Medulla; Kidney Tubular Necrosis, Acute; Nitric Oxide; Oxidative Stress; Pressure; Rats; Rats, Inbred Dahl; Renal Circulation; Sodium Chloride, Dietary; Superoxides; Vasoconstrictor Agents | 2006 |
Role of angiotensin II receptor blockers in atherosclerotic plaque stability.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Biphenyl Compounds; Carotid Arteries; Collagen; Cyclooxygenase 2; Humans; Hypertension; Irbesartan; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Randomized Controlled Trials as Topic; Tetrazoles | 2006 |
Renal and vascular hypertension-induced inflammation: role of angiotensin II.
Topics: Angiotensin II; Chemokines; Cytokines; Female; Humans; Hypertension; Hypertension, Renal; Inflammation; Inflammation Mediators; Male; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Risk Factors; Sensitivity and Specificity | 2006 |
[Uremic syndrome: Pathogenesis, pathophysiology, and therapy].
Topics: Amyloidosis; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Calcinosis; Calcium Channel Blockers; Charcoal; Dialysis; Drug Therapy, Combination; Humans; Hyperparathyroidism, Secondary; Hypertension; Kidney Failure, Chronic; Toxins, Biological; Uremia; Vascular Diseases | 2006 |
Vascular tone control in humans: insights from studies in Bartter's/Gitelman's syndromes.
Topics: Angiotensin II; Bartter Syndrome; Blood Pressure; Blood Vessels; Calcium; Cardiovascular System; Endothelium, Vascular; GTP-Binding Proteins; Humans; Hypertension; Hypertrophy; Juxtaglomerular Apparatus; Magnesium; Oxidative Stress; Signal Transduction; Syndrome | 2006 |
Signaling crosstalk angiotensin II receptor subtypes and insulin.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Mice; Models, Animal; Rats; Receptor Cross-Talk; Receptors, Angiotensin; Risk Factors; Signal Transduction | 2006 |
Sexual dysfunction in essential hypertension: myth or reality?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Erectile Dysfunction; Female; Humans; Hypertension; Male; Middle Aged; Phosphodiesterase Inhibitors; Prevalence; Quality of Life; Risk Factors; Sexual Dysfunction, Physiological; Vasoconstrictor Agents | 2006 |
Interaction between nitric oxide and angiotensin II in the endothelium: role in atherosclerosis and hypertension.
Topics: Angiotensin II; Atherosclerosis; Endothelium, Vascular; Humans; Hypertension; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Scavenger Receptors, Class E; Superoxides | 2006 |
Angiotensin-sympathetic system interactions in cardiovascular and metabolic disease.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Heart Failure; Humans; Hypertension; Insulin Resistance; Metabolic Syndrome; Renin-Angiotensin System; Sympathetic Nervous System | 2006 |
Calcium channel blockers, endothelial dysfunction, and combination therapy.
Topics: Aged; Angiotensin II; Antihypertensive Agents; Atherosclerosis; Calcium Channel Blockers; Drug Therapy, Combination; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Reactive Oxygen Species | 2005 |
Salt sensitivity and hypertension after menopause: role of nitric oxide and angiotensin II.
Topics: Angiotensin II; Animals; Estrogens; Female; Humans; Hypertension; Middle Aged; Models, Biological; Nitric Oxide; Postmenopause; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary | 2006 |
Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Arteries; Humans; Hypertension; Inflammation; Mineralocorticoid Receptor Antagonists; Renin; Renin-Angiotensin System | 2006 |
Is hypertension an inflammatory process?
Topics: Angiotensin II; C-Reactive Protein; Humans; Hypertension; Inflammation; Interleukin-1; Interleukin-6; Oxidative Stress; Tumor Necrosis Factor-alpha | 2006 |
Angiotensin II antagonists: clinical experience in the treatment of hypertension, prevention of cardiovascular outcomes and renal protection in diabetic nephropathy and proteinuria.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular System; Diabetic Nephropathies; Humans; Hypertension; Irbesartan; Kidney; Losartan; Proteinuria; Tetrazoles | 2006 |
[The main determinants of endothelial dysfunction].
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Arteriosclerosis; Biological Availability; Diabetes Mellitus; Endothelium, Vascular; Free Radicals; Heart Failure; Homocysteine; Humans; Hypertension; Hypolipidemic Agents; Middle Aged; Models, Biological; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Potassium Channels; Reactive Oxygen Species; Renal Insufficiency; Risk Factors; Vasodilation | 2006 |
Role of limbic peptidergic circuits in regulation of arterial pressure, relevant to development of essential hypertension.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; beta-Endorphin; Blood Pressure; Corticotropin-Releasing Hormone; Humans; Hypertension; Limbic System; Neuropeptides; Substance P | 2006 |
Ventricular hypertrophy and hypertension: prognostic elements and implications for management.
Topics: Adrenergic Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Carbazoles; Carvedilol; Chi-Square Distribution; Cohort Studies; Coronary Disease; Death, Sudden, Cardiac; Diuretics; Drug Therapy, Combination; Echocardiography; Electroencephalography; Enalapril; Female; Follow-Up Studies; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Indapamide; Logistic Models; Losartan; Male; Multivariate Analysis; Prognosis; Propanolamines; Prospective Studies; Randomized Controlled Trials as Topic; Risk; Risk Assessment; Risk Factors; Sex Factors; Stroke; Survival Analysis; Telmisartan | 2006 |
Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Aortic Aneurysm; Chymases; Fibrosis; Heart Diseases; Humans; Hypertension; Mast Cells; Myocardial Infarction; Neovascularization, Pathologic; Serine Proteinase Inhibitors | 2006 |
Diabetic nephropathy: from mechanisms to rational therapies.
Topics: Angiotensin II; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelin-1; Glycation End Products, Advanced; Humans; Hypertension; Protein Kinase C; Urotensins | 2006 |
[Angiotensin II and superoxide production].
Topics: Angiotensin II; Animals; Gene Deletion; Humans; Hypertension; Mitochondria; NADPH Oxidases; Reactive Oxygen Species | 2006 |
[Tissue angiotensin II generating system].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteriosclerosis; Chymases; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Serine Endopeptidases | 2006 |
[Role of renin-angiotensin system in cardiovascular remodeling].
Topics: Angiotensin II; Animals; Cardiomegaly; Humans; Hypertension; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Transcription Factor AP-1; Ventricular Remodeling | 2006 |
[Oxidative stress].
Topics: Angiotensin II; Arteriosclerosis; Humans; Hypertension; Inflammation; Lipoproteins, LDL; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Risk Factors | 2006 |
[Regulatory mechanisms of cardiovascular remodeling in hypertension].
Topics: Angiotensin II; Animals; Cardiovascular System; Cyclic AMP Response Element-Binding Protein; Early Growth Response Protein 1; Humans; Hypertension; Kruppel-Like Transcription Factors; NF-kappa B; NFATC Transcription Factors; Oxidative Stress; Peroxisome Proliferator-Activated Receptors; Transcription Factors | 2006 |
[Development of animal models for the metabolic syndrome with hypertension].
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Insulin Resistance; Metabolic Syndrome; Mice; Mutation; Obesity; Rats; Rats, Inbred SHR; Receptors, Cell Surface; Receptors, Leptin; Tumor Necrosis Factor-alpha | 2006 |
[Protective effect of ARB on vascular diseases].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteriosclerosis; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; MAP Kinase Kinase Kinase 5; Nitric Oxide; Oxidative Stress | 2006 |
[Clinical significance of non-ACE-dependent angiotensin II-forming system].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cardiovascular Diseases; Chymases; Enzyme Inhibitors; Humans; Hypertension; Serine Endopeptidases | 2006 |
[Acceleration of cellular senescence].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cellular Senescence; Endothelium, Vascular; Humans; Hypertension; Muscle, Smooth, Vascular; Oxidative Stress; Telomerase; Telomere | 2006 |
[Apoptosis of vascular cells].
Topics: Angiotensin II; Antioxidants; Apoptosis; Arteriosclerosis; Endothelium, Vascular; Estrogens; fas Receptor; Growth Substances; Humans; Hypertension; Lipopolysaccharides; Lipoproteins, LDL; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Stress, Mechanical; Tumor Necrosis Factor-alpha | 2006 |
[Mechanisms of hypertension in the central nervous system].
Topics: Acetylcholine; Angiotensin II; Animals; Humans; Hypertension; Hypothalamus, Anterior; Medulla Oblongata; Neurons; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium; Stress, Psychological | 2006 |
Clinical evidence for the cardiovascular benefits of angiotensin receptor blockers.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Cardiac Output, Low; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Humans; Hypertension; Kidney Diseases; Renin-Angiotensin System | 2006 |
Hypertension in Cushing's syndrome.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Angiotensin II; Antihypertensive Agents; Atherosclerosis; Catecholamines; Cushing Syndrome; Glucocorticoids; Humans; Hypertension; Models, Biological; Renin-Angiotensin System; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Renal hemodynamics and permselectivity.
Topics: Angiotensin II; Animals; Diffusion; Disease Models, Animal; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Glomerulus; Permeability; Pressure; Proteinuria; Rats | 1990 |
Angiotensin, bradykinin and the endothelium.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Atherosclerosis; Bradykinin; Bradykinin Receptor Antagonists; Endothelium, Vascular; Humans; Hypertension; Inflammation; Peptides; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Bradykinin; Signal Transduction | 2006 |
The metabolic syndrome: role of skeletal muscle metabolism.
Topics: Angiotensin II; Cytokines; Energy Metabolism; Humans; Hypertension; Inflammation; Insulin; Metabolic Syndrome; Mitochondria; Muscle, Skeletal; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2006 |
Spotlight on renin. The renin system, salt-sensitivity and metabolic syndrome.
Topics: Adrenomedullin; Angiotensin II; Cardiovascular Diseases; Humans; Hypertension; Insulin Resistance; Metabolic Syndrome; Renin-Angiotensin System; Sodium Chloride | 2006 |
Novel therapies blocking the renin-angiotensin-aldosterone system in the management of hypertension and related disorders.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; DNA, Antisense; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Neprilysin; Peptidyl-Dipeptidase A; Protease Inhibitors; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 1; Receptors, Growth Factor; Renin; Renin-Angiotensin System; Vaccines | 2007 |
Inflammation and the metabolic syndrome: role of angiotensin II and oxidative stress.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; C-Reactive Protein; Humans; Hypertension; Inflammation Mediators; Metabolic Syndrome; NADPH Oxidases; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species | 2006 |
Reactive oxygen species in the neuropathogenesis of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Humans; Hypertension; NADPH Oxidases; Neurons; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Transcription Factors | 2006 |
Renal sympathetic nerve activity in the development of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Kidney; Sympathetic Nervous System | 2006 |
Aldosterone and the vasculature: mechanisms mediating resistant hypertension.
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Endothelium; Humans; Hypertension; Muscle, Smooth, Vascular; Recurrence; Renin-Angiotensin System; Treatment Failure | 2007 |
Neuropeptides in neurogenic disorders of the cardiovascular control.
Topics: Angiotensin II; Brain; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Cytokines; Heart Failure; Humans; Hypertension; Nerve Net; Neuropeptides; Neurosecretory Systems; Stress, Psychological; Vasopressins | 2006 |
Mechanisms of protective effects induced by blockade of the renin-angiotensin system: novel role of the pancreatic islet angiotensin-generating system in Type 2 diabetes.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Heart Failure; Humans; Hypertension; Insulin Resistance; Islets of Langerhans; Renin-Angiotensin System; Vasoconstrictor Agents | 2007 |
The emerging role of angiotensin-converting enzyme-2 in the kidney.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diabetic Nephropathies; Hypertension; Kidney; Kidney Tubules, Proximal; Male; Mice; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2007 |
Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions.
Topics: Aldosterone; Angiotensin II; Cell Adhesion Molecules; Cytokines; Diabetes Complications; Diabetes Mellitus, Type 2; Disease Progression; Humans; Hypertension; NF-kappa B; Renin-Angiotensin System; Vasculitis | 2007 |
Angiotensin II reactivation and aldosterone escape phenomena in renin-angiotensin-aldosterone system blockade: is oral renin inhibition the solution?
Topics: Administration, Oral; Aldosterone; Amides; Angiotensin II; Animals; Antihypertensive Agents; Enzyme Activation; Enzyme Reactivators; Fumarates; Heart Failure; Humans; Hypertension; Randomized Controlled Trials as Topic; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 2007 |
In hypertension, the kidney rules.
Topics: Angiotensin II; Animals; Blood Pressure; Homeostasis; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Vascular Resistance | 2007 |
Intrarenal renin-angiotensin system and counteracting protective mechanisms in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Carbon Monoxide; Cyclooxygenase Inhibitors; Eicosanoids; Heme; Heme Oxygenase (Decyclizing); Hypertension; Hypertension, Renal; Renin-Angiotensin System | 2007 |
Is angiotensin II a direct mediator of left ventricular hypertrophy? Time for another look.
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Transgenic; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Vasoconstriction; Ventricular Myosins | 2007 |
Sex differences in angiotensin II- induced hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Estrogens; Female; Hypertension; Infusions, Intravenous; Male; Mice; Nitric Oxide Synthase; Ovariectomy; Reactive Oxygen Species; Sex Characteristics; Testosterone; Vasoconstrictor Agents | 2007 |
[Insulin and angiotensin II signaling pathways cross-talk: implications with the association between diabetes mellitus, arterial hypertension and cardiovascular disease].
Topics: Angiotensin II; Animals; Diabetes Mellitus; Humans; Hypertension; Insulin; Insulin Resistance; MAP Kinase Signaling System; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins | 2007 |
Cardiovascular effects of angiotensin II in the rostral ventrolateral medulla: the push-pull hypothesis.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Humans; Hypertension; Medulla Oblongata; Neurons; Receptor, Angiotensin, Type 1; Signal Transduction; Sympathetic Nervous System | 2007 |
Circulating angiotensin II and dietary salt: converging signals for neurogenic hypertension.
Topics: Angiotensin II; Animals; Humans; Hypertension; Neural Pathways; Neuronal Plasticity; Signal Transduction; Sodium Chloride, Dietary; Sympathetic Nervous System; Vascular Capacitance; Vascular Resistance | 2007 |
Vascular-brain signaling in hypertension: role of angiotensin II and nitric oxide.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Nitric Oxide Synthase Type III; RNA; Signal Transduction; Up-Regulation | 2007 |
Angiotensin II and oxidative stress.
Topics: Angiotensin II; Cardiovascular Diseases; Cardiovascular System; Clinical Trials as Topic; Humans; Hypertension; NADP; Oxidative Stress; Reactive Oxygen Species | 2007 |
Renin-angiotensin-aldosterone system and oxidative stress in cardiovascular insulin resistance.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Endothelium, Vascular; Humans; Hypertension; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Kidney Diseases; Metabolic Syndrome; Mineralocorticoids; Muscle, Skeletal; Myocardium; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Factors; Signal Transduction | 2007 |
[Hypertension in postmenopausal women --selected pathomechanisms].
Topics: Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Body Mass Index; Dyslipidemias; Estrogen Replacement Therapy; Estrogens; Female; Humans; Hypertension; Middle Aged; Obesity; Postmenopause; Renin-Angiotensin System | 2006 |
Nitric oxide and superoxide interactions in the kidney and their implication in the development of salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Disease Models, Animal; Dogs; Enzyme Inhibitors; Hypertension; Kidney; Mice; Natriuresis; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Sodium Chloride; Superoxides | 2007 |
Emerging concepts of regulation of angiotensin II receptors: new players and targets for traditional receptors.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Autoantibodies; Dimerization; Drug Inverse Agonism; GTP-Binding Proteins; Humans; Hypertension; Kruppel-Like Transcription Factors; Ligands; Membrane Transport Proteins; Multiprotein Complexes; Protein Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Tumor Suppressor Proteins; Ubiquitin-Conjugating Enzymes | 2007 |
[New therapeutic targets for ACE inhibitors and angiotensin receptor blockers].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypertension; Losartan; Metabolic Syndrome; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Risk Reduction Behavior; Telmisartan; Treatment Outcome | 2007 |
From mitochondria to disease: role of the renin-angiotensin system.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Diabetes Mellitus; Humans; Hypertension; Mitochondria; Mitochondrial Diseases; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2007 |
The role of nitric oxide in the maintenance of vasoactive balance.
Topics: Angiotensin II; Animals; Endothelins; Endothelium, Vascular; Homeostasis; Humans; Hypertension; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
[Angiotensin type 2 receptor-dependent vasodilation].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Bradykinin; Humans; Hypertension; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilation | 2007 |
The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Chronic Disease; Disease Models, Animal; Humans; Hypertension; Hypertension, Renal; Kidney; Kidney Diseases; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2007 |
Common pathways of hypercholesterolemia and hypertension leading to atherothrombosis: the need for a global approach in the management of cardiovascular risk factors.
Topics: Angiotensin II; Cardiovascular Diseases; Humans; Hypercholesterolemia; Hypertension; Risk Factors; Thrombosis | 2007 |
Pathophysiology of target-organ disease: does angiotensin II remain the key?
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Disease Progression; Humans; Hypertension; Losartan; Myocardial Infarction; Renin; Renin-Angiotensin System; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
New insights into the importance of aminopeptidase A in hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Female; Glutamyl Aminopeptidase; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Renin-Angiotensin System | 2008 |
Aminopeptidase N in arterial hypertension.
Topics: Angiotensin II; Angiotensin III; Animals; Blood Pressure; CD13 Antigens; Humans; Hypertension; Rats; Rats, Inbred Dahl; Rats, Inbred SHR | 2008 |
Aminopeptidase A inhibitors as centrally acting antihypertensive agents.
Topics: Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Disulfides; Enzyme Inhibitors; Glutamyl Aminopeptidase; Hypertension; Models, Biological; Renin-Angiotensin System; Sulfonic Acids | 2008 |
Update on the treatment of diabetic retinopathy.
Topics: Adrenal Cortex Hormones; Aldehyde Reductase; Angiotensin II; Antihypertensive Agents; Blood Glucose; Clofibric Acid; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Dyslipidemias; Enzyme Inhibitors; Glycation End Products, Advanced; Human Growth Hormone; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Insulin; Laser Coagulation; Protein Kinase C; Vascular Endothelial Growth Factor A; Vitamin E | 2008 |
Vascular angiotensin AT2 receptors in hypertension and ageing.
Topics: Aging; Angiotensin II; Blood Vessels; Humans; Hypertension; Receptor, Angiotensin, Type 2 | 2008 |
The renin-angiotensin-aldosterone system: a pivotal role in insulin sensitivity and glycemic control.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Diabetes Mellitus; Homeostasis; Humans; Hypertension; Insulin; Insulin Resistance; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2008 |
Angiotensin-converting enzyme 2: possible role in hypertension and kidney disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Biological Assay; Humans; Hypertension; Kidney; Kidney Diseases; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2008 |
Androgens stimulate proximal tubule transport.
Topics: Androgens; Angiotensin II; Animals; Blood Pressure; Dihydrotestosterone; Disease Models, Animal; Hypertension; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Up-Regulation | 2008 |
Concomitant calcium entry blockade and inhibition of the renin-angiotensin system: a rational and effective means for treating hypertension.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Calcium Channel Blockers; Drug Combinations; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Hypertension; Indoles; Middle Aged; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Sympathetic Nervous System; Verapamil | 2008 |
Signalling across the blood brain barrier by angiotensin II: novel implications for neurogenic hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Blood-Brain Barrier; Humans; Hypertension; Signal Transduction; Solitary Nucleus | 2008 |
Angiotensin II-dependent superoxide: effects on hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; Blood Vessels; Brain; Humans; Hypertension; Kidney; Prostaglandin-Endoperoxide Synthases; Rats; Superoxides | 2008 |
Physiological aspects of the renin-angiotensin system and peroral angiotensin converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bartter Syndrome; Humans; Hypertension; Molecular Weight; Peptidyl-Dipeptidase A; Renal Circulation; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1984 |
Disorders of the adrenal cortex: their effects on electrolyte metabolism.
Topics: Addison Disease; Adrenal Cortex Diseases; Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Cushing Syndrome; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoids; Potassium | 1984 |
Angiotensin-converting enzyme inhibitors: biochemical properties and biological actions.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Disease Models, Animal; Heart Failure; Humans; Hypertension; Kidney; Oligopeptides; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Structure-Activity Relationship; Substrate Specificity | 1984 |
[Angiotensin converting enzyme inhibitors--a new group of hypotensive drugs].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Drug Evaluation; Enalapril; Humans; Hypertension; Proline; Renin-Angiotensin System | 1984 |
An overview of the clinical pharmacology of enalapril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Dipeptides; Drug Administration Schedule; Enalapril; Enalaprilat; Heart Failure; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Kidney; Kidney Failure, Chronic; Norepinephrine; Prostaglandins; Renal Circulation; Renin | 1984 |
Renin, angiotensin, and cardiac lesions.
Topics: Angiotensin II; Animals; Arteriosclerosis; Cardiomyopathies; Catecholamines; Endothelium; Heart Ventricles; Humans; Hypertension; Myocardial Infarction; Myocardium; Neurotransmitter Agents; Protein Biosynthesis; Rabbits; Rats; Renin | 1980 |
Hypertension: relationships between pathophysiology and therapy.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Blood Pressure; Cardiac Output; Central Nervous System; Child; Diuresis; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Natriuresis; Renin; Vascular Resistance; Vasoconstriction; Vasodilation | 1980 |
Pre- and post-junctional adrenergic mechanisms and hypertension.
Topics: Angiotensin II; Animals; Blood Vessels; Exocytosis; Feedback; Humans; Hypertension; Male; Nerve Endings; Norepinephrine; Rats; Receptors, Adrenergic; Sodium-Potassium-Exchanging ATPase; Sympathetic Nervous System; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1980 |
The control of hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Diazoxide; Diuretics; Eclampsia; Female; Homeostasis; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins E; Regional Blood Flow; Secologanin Tryptamine Alkaloids; Veratrum Alkaloids | 1981 |
Measurement of the hormones of the renin system in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Volume; Body Water; Diuretics; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Kidney; Methods; Regional Blood Flow; Renal Veins; Renin; Sodium; Vasoconstriction | 1981 |
Renin in essential hypertension.
Topics: Adrenergic beta-Antagonists; Age Factors; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cardiovascular Diseases; Humans; Hypertension; Posture; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Saralasin; Sodium | 1981 |
Diabetes and arterial hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Diuretics; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Obesity; Renin; Sodium; Systole; Vascular Diseases | 1983 |
Adrenergic regulation of renin release and effects on angiotensin and aldosterone.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Animals; Dinoprostone; Dogs; Electric Stimulation; Humans; Hypertension; Kidney; Kidney Tubules, Distal; Prazosin; Prostaglandins E; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Renin; Sympathetic Nervous System | 1983 |
Hypertension, the adrenal and the kidney: lessons from pharmacologic interruption of the renin-angiotensin system.
Topics: Adrenal Glands; Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Angiotensins; Animals; Blood Pressure; Disease Models, Animal; Humans; Hydrocortisone; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Kidney; Renin; Saralasin; Teprotide | 1980 |
Peptidergic and catecholaminergic mechanisms in central blood pressure control.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Catecholamines; Disease Models, Animal; Epinephrine; Humans; Hypertension; Kinins; Neurotransmitter Agents; Norepinephrine; Peptides; Pressoreceptors; Rats; Substance P | 1980 |
[The renin-angiotensin system. Physiopathological aspects and clinical implications of hypertensive syndromes. A survey].
Topics: Acromegaly; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Cushing Syndrome; Glycoproteins; Humans; Hyperaldosteronism; Hypertension; Kidney; Kidney Diseases; Prostaglandins; Receptors, Adrenergic; Receptors, Angiotensin; Renin; Sodium; Sympathetic Nervous System; Teprotide | 1981 |
[Role of renin-angiotensin system and its blockaders in the pathogenesis of arterial hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Hypertension; Renin; Renin-Angiotensin System; Teprotide | 1982 |
[Renin-angiotensin system blockers].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Humans; Hypertension; Kidney; Oligopeptides; Pepstatins; Renin; Renin-Angiotensin System; Teprotide | 1982 |
[Blood pressure regulation and shock].
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Endorphins; Hypertension; Nerve Tissue Proteins; Neurotensin; Rats; Rats, Inbred Strains; Shock; Substance P; Vasopressins | 1983 |
[Polypeptides and antagonists].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Humans; Hypertension; Inflammation; Kallikreins; Kinins; Neurotensin; Peptides; Renin-Angiotensin System; Substance P; Vasoactive Intestinal Peptide | 1984 |
Haemodynamic responses to specific renin-angiotensin inhibitors in hypertension and congestive heart failure. A review.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Dipeptides; Enalapril; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Kinetics; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Renin; Renin-Angiotensin System; Teprotide | 1984 |
Monotherapy of hypertension with angiotensin-converting enzyme inhibitors.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Trials as Topic; Dipeptides; Enalapril; Heart Failure; Humans; Hypertension; Proline; Racial Groups; Teprotide; Time Factors | 1984 |
The multifactorial role of catecholamines in hypertensive cardiac hypertrophy.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Catecholamines; Coronary Circulation; Heart Ventricles; Humans; Hypertension; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred Strains | 1982 |
Control of vascular responsiveness during human pregnancy.
Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Aspirin; Blood Vessels; Cyclic AMP; Female; Humans; Hypertension; Indomethacin; Muscle, Smooth, Vascular; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Prostaglandins; Theophylline | 1980 |
Drugs inhibiting the renin - angiotensin system.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Cardiac Output; Dogs; Hypertension; Lipids; Pepstatins; Phospholipids; Rats; Renin; Structure-Activity Relationship; Substrate Specificity | 1981 |
The renin-angiotensin system in pregnancy.
Topics: Amniotic Fluid; Angiotensin II; Angiotensinogen; Endopeptidases; Female; Fetal Blood; Fetus; Humans; Hypertension; Juxtaglomerular Apparatus; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins E; Renin; Renin-Angiotensin System | 1981 |
[Angiotensin II and its receptors].
Topics: Adrenal Cortex; Angiotensin II; Animals; Brain Chemistry; Humans; Hypertension; Muscle, Smooth, Vascular; Rats; Receptors, Angiotensin; Receptors, Cell Surface | 1981 |
Angiotensin converting enzyme (ACE) inhibitors.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Heart Failure; Humans; Hypertension; Kallikreins; Kidney; Kinins; Prostaglandins; Renin | 1982 |
[Renin-angiotensin-aldosterone function tests].
Topics: Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Desoxycorticosterone; Dexamethasone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Male; Pregnancy; Renin; Renin-Angiotensin System; Sodium Chloride | 1982 |
Peripheral neurogenic factors in acute and chronic alterations of arterial pressure.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Catecholamines; Desoxycorticosterone; Disease Models, Animal; Humans; Hypertension; Neurons; Norepinephrine; Peripheral Nerves; Rats; Receptors, Adrenergic, beta; Renin-Angiotensin System; Sympathetic Nervous System | 1983 |
Minireview. Presynaptic receptors and alterations in norepinephrine release in spontaneously hypertensive rats.
Topics: Adenosine; Angiotensin II; Animals; Blood Vessels; Calcium; Dinoprostone; Exocytosis; Hypertension; Norepinephrine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Angiotensin; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Purinergic; Sympathetic Nervous System; Synapses; Vascular Resistance; Vasoconstriction | 1983 |
The endocrinology of pregnancy-induced hypertension.
Topics: Adolescent; Adrenocorticotropic Hormone; Angiotensin II; Angiotensinogen; Animals; Estrogens; Female; Humans; Hypertension; Maternal-Fetal Exchange; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Prolactin; Prostaglandins; Renin; Renin-Angiotensin System | 1983 |
ACTH dependent hypertension.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Angiotensin II; Animals; Body Fluids; Cardiovascular System; Central Nervous System; Dogs; Glucocorticoids; Humans; Hypertension; Ion Channels; Mineralocorticoids; Nervous System; Rats; Renin-Angiotensin System; Sheep; Sodium | 1984 |
[Renin-angiotensin system blocking drugs in the diagnosis and treatment of arterial hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Hypertension; Proline; Renin-Angiotensin System; Saralasin | 1984 |
Age and the renin-angiotensin system.
Topics: Adolescent; Adult; Aged; Aging; Angiotensin II; Child; Child, Preschool; Humans; Hypertension; Infant; Infant, Newborn; Middle Aged; Renin; Renin-Angiotensin System | 1983 |
Role of vasopressin in the control of arterial pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Heart; Humans; Hypertension; Vasopressins | 1983 |
Interactions between vasopressin and the renin--angiotensin system.
Topics: Angiotensin II; Animals; Dogs; Hemorrhage; Humans; Hypertension; Male; Pituitary Gland; Posture; Rats; Renin; Renin-Angiotensin System; Sodium; Supraoptic Nucleus; Thirst; Vasoconstriction; Vasopressins | 1983 |
The pathogenesis of hypertension: the Baker concerto.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Hemodynamics; Humans; Hypertension; Hypertension, Renovascular; Hypertrophy; Sympathetic Nervous System | 1984 |
[The renin-angiotensin-aldosterone system in normal pregnancy and pregnancy complicated by hypertension (review of the literature)].
Topics: Angiotensin II; Blood Pressure; Female; Glomerular Filtration Rate; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Muscle, Smooth, Vascular; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Renin-Angiotensin System; Sodium | 1983 |
Effects of brain renin-angiotensin on cardiovascular function and saline intake in awake dogs.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Dogs; Drinking; Female; Hemodynamics; Hypertension; Injections, Intraventricular; Male; Renin; Sodium Chloride; Vascular Resistance | 1984 |
Interaction between the natriuretic effects of renal perfusion pressure and the antinatriuretic effects of angiotensin and aldosterone in control of sodium excretion.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Hypertension; Infusions, Intra-Arterial; Kidney; Natriuresis; Perfusion; Pressure; Renal Artery; Water-Electrolyte Balance | 1984 |
The kidney and hypertension.
Topics: Angiotensin II; Animals; Humans; Hypertension; Kidney; Prostaglandins; Prostaglandins E; Rats; Renin; Renin-Angiotensin System; Sodium | 1982 |
The sixth Volhard Lecture: Causal and homoeostatic factors in hypertension.
Topics: Angiotensin II; Animals; Cardiac Output; Cardiomyopathies; Dogs; Hemodynamics; Homeostasis; Humans; Hypertension; Hypertension, Renal; Norepinephrine; Rabbits; Renal Artery Obstruction; Renin-Angiotensin System; Vascular Resistance; Vasopressins | 1982 |
[New therapeutic approaches to arterial hypertension].
Topics: Angiotensin II; Benzothiadiazines; Calcium; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hyperkalemia; Hypertension; Nifedipine; Renin-Angiotensin System; Sodium; Sodium Chloride Symporter Inhibitors; Vasodilation; Verapamil | 1982 |
[The catecholamine system].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Dogs; Drug Interactions; Humans; Hypertension; Hyponatremia; Rats; Renin; Renin-Angiotensin System | 1982 |
Renin in the brain and neuroblastoma cells: an endogenous and intracellular system.
Topics: Angiotensin I; Angiotensin II; Animals; Antibodies; Brain; Cathepsin D; Cathepsins; Cell Line; Chemical Phenomena; Chemistry, Physical; Chromatography, Affinity; Histocytochemistry; Hydrogen-Ion Concentration; Hypertension; Immunologic Techniques; Mice; Nephrectomy; Neuroblastoma; Rats; Renin; Tissue Distribution | 1982 |
Endocrine mechanisms in the pathogenesis of essential hypertension. III. Special reference on the interrelations between the prostaglandin and kallikrein-kinin systems.
Topics: 18-Hydroxydesoxycorticosterone; Angiotensin II; Animals; Blood Pressure; Hypertension; Kallikreins; Kinins; Prostaglandins; Rats; Renin; Saralasin; Sodium; Water | 1981 |
Pathophysiology of the syndrome of hyporeninemic hypoaldosteronism.
Topics: Acidosis; Aged; Aldosterone; Ammonia; Angiotensin II; Bicarbonates; Cations, Monovalent; Extracellular Space; Glomerular Filtration Rate; Humans; Hydrogen-Ion Concentration; Hyperkalemia; Hypertension; Hyponatremia; Juxtaglomerular Apparatus; Kidney; Middle Aged; Natriuresis; Renin; Sodium; Sympathetic Nervous System; Syndrome | 1980 |
Pathophysiological mechanisms in essential hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Body Fluids; Hemodynamics; Humans; Hypertension; Kidney; Regional Blood Flow; Renin; Sympathetic Nervous System | 1980 |
Malignant hypertension: mechanisms and management.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Necrosis; Renin | 1980 |
Neural mechanisms in hypertension.
Topics: Angiotensin II; Animals; Brain; Catecholamines; Disease Models, Animal; Humans; Hypertension; Hypothalamus, Anterior; Pressoreceptors; Receptors, Angiotensin; Reflex; Renin; Vasopressins | 1980 |
[Effect of oral contraceptives on the circulatory system].
Topics: Aldosterone; Angiotensin II; Cardiovascular Diseases; Cerebrovascular Disorders; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Coronary Disease; Female; Humans; Hypertension; Renin; Stimulation, Chemical; Thrombosis | 1980 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Bradykinin; Captopril; Dogs; Hemodynamics; Hydralazine; Hydrochlorothiazide; Hypertension; Kallikreins; Kidney; Proline; Prostaglandins; Rabbits; Rats; Renin; Sodium | 1980 |
Hypertension: diagnostic test strategies.
Topics: Angiotensin II; Catecholamines; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Kidney; Pheochromocytoma; Potassium; Prostaglandins; Renin; Sodium; Urography; Vanilmandelic Acid | 1980 |
Regulation of aldosterone secretion in normotensive and hypertensive man.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Humans; Hypertension; Potassium; Renin; Sodium | 1980 |
Captopril: a preliminary review of its pharmacological properties and therapeutic efficacy.
Topics: Aldosterone; Angiotensin II; Captopril; Drug Interactions; Heart Failure; Hemodynamics; Humans; Hypertension; Kallikreins; Kinetics; Kinins; Proline; Prostaglandins; Renin; Scleroderma, Systemic | 1980 |
[Pathobiochemistry of essential hypertension].
Topics: Angiotensin II; Humans; Hypertension; Kallikreins; Kinins; Renin; Sympathetic Nervous System | 1980 |
The renin-angiotensin system and aldosterone in hypertension: a brief review of some aspects.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Renin | 1981 |
Pressor factors and cardiovascular pressor reponsiveness in essential hypertension.
Topics: Angiotensin II; Blood Pressure; Cardiovascular System; Humans; Hypertension; Prolactin; Renin; Sodium; Sympathetic Nervous System | 1981 |
The role of the renin-angiotensin-aldosterone system in circulatory control and hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin | 1981 |
[Significance of the saralasin infusion test in the diagnosis of arterial hypertension].
Topics: Adult; Aged; Angiotensin II; Creatinine; Electrolytes; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Middle Aged; Prognosis; Renin; Renin-Angiotensin System; Saralasin | 1980 |
Oestrogens and hypertension.
Topics: Adolescent; Adult; Age Factors; Angiotensin II; Cardiac Output; Cardiovascular Diseases; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Menopause; Middle Aged; Norethindrone; Norethindrone Acetate; Pituitary-Adrenal System; Progestins; Prospective Studies; Prostaglandins; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1981 |
[Essential arterial hypertension: humoral factors].
Topics: Adrenal Glands; Angiotensin II; Catecholamines; Humans; Hypertension; Hypothalamus; Mineralocorticoids; Prostaglandins; Renin; Renin-Angiotensin System; Sodium | 1981 |
Vascular smooth muscle polyploidy in genetic hypertension: the role of angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Cell Cycle; Humans; Hypertension; Imidazoles; Losartan; Models, Cardiovascular; Muscle, Smooth, Vascular; Ploidies; Tetrazoles | 1995 |
[Arterial hypertension and vascular resistance].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Endothelins; Endothelium, Vascular; Humans; Hypertension; Muscle, Smooth, Vascular; Nitric Oxide; Rats; Rats, Inbred SHR; Vascular Resistance | 1995 |
AT1 receptors and angiotensin actions in the brain and neuronal cultures of normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Brain Chemistry; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 1995 |
[Alternative pathways of angiotensin I. The glimpse of new possibilities in the treatment of hypertension and heart failure].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Circulation; Blood Pressure; Heart Failure; Humans; Hypertension; Renin-Angiotensin System | 1995 |
The cardiac renin-angiotensin-aldosterone system and hypertensive cardiac hypertrophy.
Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Cardiomegaly; Humans; Hypertension; Myocardial Infarction; Myocardium; Renin-Angiotensin System | 1995 |
Role of angiotensin II and prostaglandin E2 in regulating cardiac fibroblast collagen turnover.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibody Formation; Collagen; Collagenases; Connective Tissue; Dinoprostone; Endomyocardial Fibrosis; Fibroblasts; Heart Failure; Humans; Hypertension; Matrix Metalloproteinase 1; Myocardial Infarction; Myocardium; Neurotransmitter Agents; Renin-Angiotensin System; Ventricular Dysfunction, Left | 1995 |
Role of the renin-angiotensin system in essential hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hypertension; Renin-Angiotensin System | 1995 |
Genetic determinants of human hypertension.
Topics: Angiotensin II; Blood Pressure; Causality; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme System; Genetic Linkage; Humans; Hypertension; Mutation; Sodium Channels; Steroid 11-beta-Hydroxylase; Syndrome | 1995 |
Molecular basis of human hypertension: the role of angiotensin.
Topics: Angiotensin II; Angiotensinogen; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Myocardial Infarction; Peptidyl-Dipeptidase A; Pre-Eclampsia; Pregnancy; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1995 |
Pathophysiology of smooth muscle in hypertension.
Topics: Angiotensin II; Animals; Arteries; Blood Vessels; Endothelium; Humans; Hypertension; Muscle, Smooth, Vascular | 1995 |
[Angiotensin II receptor antagonists].
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Hemodynamics; Humans; Hypertension; Imidazoles; Losartan; Molecular Sequence Data; Pyridines; Receptors, Angiotensin; Renin-Angiotensin System; Saralasin; Tetrazoles | 1995 |
[The kidney in essential arterial hypertension: should microalbuminuria excretion be measured?].
Topics: Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Kidney; Rabbits; Risk Factors | 1995 |
Hypertensive cerebrovascular disease and the renin-angiotensin system.
Topics: Angiotensin II; Animals; Arteriosclerosis; Carotid Artery Diseases; Cerebral Hemorrhage; Cerebrovascular Disorders; Humans; Hypertension; Intracranial Embolism and Thrombosis; Renin-Angiotensin System | 1995 |
Pressor and subpressor angiotensin II administration. Two experimental models of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Humans; Hypertension | 1995 |
The chymase-angiotensin system in humans: biochemistry, molecular biology and potential role in cardiovascular diseases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Chymases; Heart Diseases; Humans; Hypertension; Molecular Biology; Serine Endopeptidases | 1995 |
Modulation of the renin-angiotensin-aldosterone system and cough.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cough; Drug Evaluation; Female; Humans; Hypertension; Male; Renin-Angiotensin System | 1995 |
Dose-response relationships of ACE inhibitors and angiotensin II blockers.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; Heart Failure; Hemodynamics; Humans; Hypertension; Receptors, Angiotensin | 1994 |
Tissue angiotensin II system in the human heart.
Topics: Angiotensin II; Animals; Atrial Function; Chymases; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Hypertension; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin-Angiotensin System; Serine Endopeptidases | 1994 |
Angiotensin II receptor subtypes: selective antagonists and functional correlates.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Endothelium, Vascular; Heart Failure; Hemodynamics; Humans; Hypertension; Receptors, Angiotensin | 1994 |
Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Cardiovascular System; Endothelium, Vascular; Humans; Hypertension; Hypertrophy, Left Ventricular; Kallikrein-Kinin System; Kinins; Molecular Sequence Data; Myocardial Ischemia; Nitric Oxide; Rabbits; Rats; Reperfusion Injury | 1995 |
Tissue angiotensin generation and regulation of vascular tone.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Cardiovascular Diseases; Humans; Hypertension; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction | 1995 |
[Molecular biology and cardiac and vascular changes in hypertension: focus on the renin-angiotensin system].
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Arteriosclerosis; Cardiovascular Diseases; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Coronary Disease; Female; Genetic Markers; Humans; Hypertension; Hypertension, Renal; Male; Mice; Mice, Inbred DBA; Mice, Transgenic; Middle Aged; Prospective Studies; Rats; Renin-Angiotensin System; Risk Factors | 1994 |
Angiotensin II antagonists DuP 753 and TCV 116.
Topics: Administration, Oral; Angiotensin II; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Losartan; Renin-Angiotensin System; Tetrazoles | 1994 |
The renin-angiotensin system in the heart and vascular wall: new therapeutic aspects.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Coronary Disease; Endothelium, Vascular; Heart Failure; Humans; Hypertension; Myocardial Infarction; Myocardium; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1994 |
Cardiovascular disease and hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Humans; Hypertension | 1993 |
Angiotensin converting enzyme inhibitors: inhibition of growth, a novel mechanism of action.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiomegaly; Coronary Disease; Heart; Humans; Hyperplasia; Hypertension; Muscle Development; Muscle, Smooth, Vascular; Tunica Intima | 1994 |
Role of ACE inhibitors in hypertension complicated by vascular disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteriosclerosis; Cerebrovascular Circulation; Cerebrovascular Disorders; Coronary Disease; Humans; Hypertension; Peripheral Vascular Diseases | 1994 |
Hemodynamic effects of inhibitors of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Hemodynamics; Humans; Hypertension; Renin; Renin-Angiotensin System | 1994 |
A new myocardial conversion of angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Chymases; Coronary Artery Disease; Heart Failure; Humans; Hypertension; Myocardium; Renin-Angiotensin System; Serine Endopeptidases | 1994 |
Control of vascular reactivity in pregnancy: the basis for therapeutic approaches to prevent pregnancy-induced hypertension.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Metabolic Clearance Rate; Pregnancy; Pregnancy Complications, Cardiovascular; Renin-Angiotensin System; Vascular Resistance | 1994 |
Systemic hypertension versus intraglomerular hypertension in progression.
Topics: Angiotensin II; Animals; Glomerulosclerosis, Focal Segmental; Humans; Hypertension; Kidney Failure, Chronic; Kidney Glomerulus | 1994 |
Evaluation of methods used in the prediction of hypertensive disorders of pregnancy.
Topics: Adult; Angiotensin II; Blood Pressure; Calcium; Cohort Studies; Exercise Test; Female; Fibronectins; Hematocrit; Humans; Hypertension; Platelet Count; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular; Sensitivity and Specificity; Ultrasonography; Uric Acid | 1994 |
Calcium antagonism: aldosterone and vascular responses to catecholamines and angiotensin II in man.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cardiovascular Physiological Phenomena; Cardiovascular System; Dihydropyridines; Humans; Hypertension; Norepinephrine; Vascular Resistance; Vasoconstriction | 1993 |
RAA system and cardiovascular control in normal subjects, hypertensives and patients with congestive heart failure.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Heart Failure; Humans; Hypertension; Renin-Angiotensin System | 1993 |
Clinical experience with angiotensin II receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Drug Tolerance; Humans; Hypertension; Imidazoles; Losartan; Renin-Angiotensin System; Tetrazoles | 1993 |
Angiotensin II antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Reference Values; Renin-Angiotensin System; Saralasin; Tetrazoles | 1993 |
Control of vascular tone by renin and angiotensin in cardiovascular disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Renin; Renin-Angiotensin System | 1993 |
Angiotensin II receptor blockade: an innovative approach to cardiovascular pharmacotherapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cardiovascular Diseases; Heart Failure; Homeostasis; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Renin-Angiotensin System; Saralasin; Tetrazoles | 1993 |
New therapeutic agents in the management of hypertension: angiotensin II-receptor antagonists and renin inhibitors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Dipeptides; Heart Failure; Humans; Hypertension; Imidazoles; Losartan; Renin; Tetrazoles | 1993 |
Anthology of the renin-angiotensin system: a one hundred reference approach to angiotensin II antagonists.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Gene Expression Regulation; Humans; Hypertension; Mutation; Renin-Angiotensin System; Sodium | 1993 |
Angiotensin II receptors and angiotensin II receptor antagonists.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cloning, Molecular; Hemodynamics; Humans; Hypertension; Imidazoles; Kidney; Losartan; Molecular Sequence Data; Pyridines; Receptors, Angiotensin; Tetrazoles | 1993 |
Fatty acids may regulate aldosterone secretion and mediate some of insulin's effects on blood pressure.
Topics: Aldosterone; Angiotensin II; Animals; Black People; Blood Pressure; Cattle; Cohort Studies; Dogs; Fatty Acids; Glucose; Humans; Hypertension; Insulin; Models, Biological; Oleic Acid; Oleic Acids; Rats; Renin; Secretory Rate; Sodium Chloride; Zona Glomerulosa | 1993 |
Angiotensin antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Imidazoles; Kidney; Losartan; Receptors, Angiotensin; Saralasin; Tetrazoles | 1993 |
[Angiotensin-converting enzyme inhibitors: effects on renal physiology and applications in hypertension and renal disease].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Kidney; Kidney Diseases; Renin-Angiotensin System | 1993 |
[Role of renin angiotensin system in the vasopressor mechanisms of hypertension--gene analyses and tissue renin angiotensin system].
Topics: Angiotensin II; DNA; Gene Expression Regulation; Humans; Hypertension; Polymorphism, Genetic; Renin; Renin-Angiotensin System; RNA, Messenger | 1995 |
Direct selective blockade of the vascular angiotensin II receptors in therapy for hypertension and severe congestive heart failure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Heart Failure; Humans; Hypertension; Imidazoles; Losartan; Prostaglandin Antagonists; Receptors, Angiotensin; Tetrazoles | 1996 |
Molecular signalling mechanisms controlling growth and function of cardiac fibroblasts.
Topics: Angiotensin II; Animals; Collagen; Fibroblasts; Gene Expression; Heart; Hypertension; Myocardial Infarction; Rats; Signal Transduction | 1995 |
Salt and left ventricular hypertrophy: what are the links?
Topics: Angiotensin II; Clinical Trials as Topic; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Renin-Angiotensin System; Sodium, Dietary; Sympathetic Nervous System | 1995 |
Role of angiotensin II in blood pressure regulation and in the pathophysiology of cardiovascular disorders.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Imidazoles; Losartan; Rats; Renin-Angiotensin System; Tetrazoles | 1995 |
Discovery of losartan, the first angiotensin II receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Humans; Hypertension; Imidazoles; Losartan; Structure-Activity Relationship; Tetrazoles | 1995 |
Effect of angiotensin II blockade on cardiac hypertrophy and remodelling: a review.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Losartan; Rats; Renin-Angiotensin System; Tetrazoles | 1995 |
The future role of losartan.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Forecasting; Humans; Hypertension; Imidazoles; Losartan; Renin-Angiotensin System; Tetrazoles | 1995 |
Angiotensin receptors and their antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1996 |
Angiotensin II receptor blockers. A new class of antihypertensive drugs.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzothiadiazines; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diuretics; Enalapril; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Multicenter Studies as Topic; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Tetrazoles | 1996 |
Cardiovascular hypertrophy: role of angiotensin II and bradykinin.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cardiomegaly; Humans; Hypertension; Rats | 1996 |
The management of hypertension in diabetes: with special reference to diabetic kidney disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Glomerular Filtration Rate; Hypertension | 1996 |
Hypertension, thermotolerance, and the "African gene": an hypothesis.
Topics: Angiotensin I; Angiotensin II; Black People; Body Temperature Regulation; Gene Deletion; Humans; Hypertension; Mutagenesis, Insertional; Peptidyl-Dipeptidase A; Prevalence; Renin-Angiotensin System; United States | 1996 |
Angiotensin II receptor inhibition. A new therapeutic principle.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Drug Evaluation, Preclinical; Hemodynamics; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Tetrazoles | 1996 |
[Angiotensin-2 receptor blockade--new therapeutic approach to treatment of hypertension].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Tetrazoles | 1996 |
Effect of angiotensin converting enzyme inhibitors on quality of life in hypertensive patients. Pharmacodynamic basis.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Brain; Cerebrovascular Circulation; Female; Humans; Hypertension; Male; Middle Aged; Quality of Life | 1996 |
Left ventricular hypertrophy in mild essential hypertension. Its progression, prediction and treatment strategy.
Topics: Angiotensin II; Antihypertensive Agents; Arteriosclerosis; Disease Progression; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Norepinephrine | 1996 |
The potential role of nitric oxide in angiotensin II-receptor blockade.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Humans; Hypertension; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred SHR; Receptors, Angiotensin | 1996 |
The diversified pharmacology of angiotensin II-receptor blockade.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Tetrazoles | 1996 |
[Losartan, an angiotensin II receptor blocker: a new trend in cardiovascular chemotherapy].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Heart Failure; Humans; Hypertension; Hypertension, Renovascular; Imidazoles; Kidney Diseases; Losartan; Myocardial Infarction; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Time Factors | 1996 |
What we can learn from the selective manipulation of dopaminergic receptors about the pathogenesis and treatment of hypertension?
Topics: Angiotensin II; Animals; Humans; Hypertension; Kidney; Mice; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine | 1996 |
Aortic collagen, aortic stiffness, and AT1 receptors in experimental and human hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Collagen; Humans; Hypertension; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1996 |
Pathologic consequences of increased angiotensin II activity.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Renin-Angiotensin System; Tetrazoles | 1996 |
Is there a link between the circulating renin-angiotensin system and coronary disease? A sceptical view.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Cohort Studies; Humans; Hypertension; Myocardial Ischemia; Prospective Studies; Rats; Renin; Renin-Angiotensin System | 1996 |
The renin-angiotensin-aldosterone system and the cardiac natriuretic peptides.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiac Output, Low; Central Nervous System; Dogs; Humans; Hypertension; Male; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Proteins; Rats; Renin; Renin-Angiotensin System; Sheep | 1996 |
Angiotensin receptors and development: the kidney.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Female; Gene Expression Regulation, Developmental; Humans; Hypertension; Kidney; Kidney Glomerulus; Organ Culture Techniques; Pregnancy; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 1996 |
Physiological actions of angiotensin II mediated by AT1 and AT2 receptors in the brain.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dorsomedial Hypothalamic Nucleus; Drinking; Hypertension; Lumbar Vertebrae; Medulla Oblongata; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Subfornical Organ; Thoracic Vertebrae; Vasoconstriction; Vasoconstrictor Agents; Ventromedial Hypothalamic Nucleus | 1996 |
Endogenous angiotensin II levels and the mechanism of action of angiotensin-converting enzyme inhibitors and angiotensin receptor type 1 antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Kidney; Renin; Tissue Distribution | 1996 |
Structural changes in the renal vasculature in the spontaneously hypertensive rat: no effect of angiotensin II blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rate; Hypertension; Kidney; Kidney Glomerulus; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1996 |
Experience with angiotensin II antagonists in hypertensive patients.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diuretics; Hemodynamics; Humans; Hypertension; Kidney; Randomized Controlled Trials as Topic; Renin; Renin-Angiotensin System; Treatment Outcome | 1996 |
Angiotensin-II-receptors: new targets for antihypertensive therapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Receptors, Angiotensin; Renin-Angiotensin System | 1997 |
[History of the pharmacologic therapy of arterial hypertension: from diuretics to angiotensin II receptor antagonists].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Diuretics; Forecasting; Humans; Hypertension | 1995 |
Interactions between angiotensin II and the sympathetic nervous system in the the long-term control of arterial pressure.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Blood Volume; Hormones; Hypertension; Renin-Angiotensin System; Sodium; Sympathetic Nervous System; Time Factors | 1997 |
[Nonmodulating essential hypertension].
Topics: Angiotensin II; Humans; Hypertension; Renin-Angiotensin System | 1996 |
[Genetic cardiovascular risk factors].
Topics: Angiotensin II; Apolipoproteins; Arteriosclerosis; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Humans; Hypertension; Lipoprotein Lipase; Point Mutation; Risk Factors | 1997 |
[Tissue angiotensin II and its impact in the treatment of arterial hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Organ Specificity; Renin-Angiotensin System | 1997 |
Vascular function in OSA.
Topics: Aldosterone; Angiotensin II; Arginine; Atrial Natriuretic Factor; Endothelium; Humans; Hypertension; Sleep Apnea Syndromes; Snoring; Sympathetic Nervous System | 1996 |
Role of the renin-angiotensin system as a risk factor for control of morbidity and mortality in coronary artery disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteriosclerosis; Coronary Disease; Humans; Hypertension; Morbidity; Myocardial Infarction; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renin-Angiotensin System; Risk Factors | 1996 |
[The cardiac renin-angiotensin system and its role in ventricular hypertrophy associated with arterial hypertension].
Topics: Angiotensin II; Animals; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular; Renin-Angiotensin System | 1997 |
[Tissue angiotensin 2--potential advantage in the therapeutic approach to the treatment of hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Humans; Hypertension | 1997 |
Activated and inactivated renin-angiotensin system in transgenic animals: from genes to blood pressure.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Humans; Hypertension; Renin; Renin-Angiotensin System | 1997 |
Kidney and hypertension: role of the juxtaglomerular apparatus.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Diuresis; Feedback; Glomerular Filtration Rate; Humans; Hypertension; In Vitro Techniques; Juxtaglomerular Apparatus; Kidney; Natriuresis; Nitric Oxide; Perfusion; Prostaglandins; Renal Circulation; Renin-Angiotensin System | 1997 |
Losartan: a new antihypertensive drug.
Topics: Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Nursing Assessment; Patient Education as Topic; Tetrazoles | 1997 |
Vasopressor mechanisms in acute aortic coarctation hypertension.
Topics: Angiotensin II; Animals; Aortic Coarctation; Dogs; Hypertension; Kidney; Rats; Renin-Angiotensin System; Vasopressins | 1997 |
The medicine of the month. Losartan (Cozaar).
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Tetrazoles | 1997 |
[Pathophysiological roles of human chymase].
Topics: Angiotensin II; Animals; Cardiovascular System; Chymases; Humans; Hypertension; Peptidyl-Dipeptidase A; Serine Endopeptidases | 1997 |
[Molecular mechanism of cardiac hypertrophy and dysfunction].
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomyopathy, Hypertrophic; Endothelin-1; Heart Failure; Humans; Hypertension; Proto-Oncogene Proteins c-raf; Rats; Signal Transduction; Stress, Mechanical | 1997 |
Angiotensin II antagonism: a new avenue of hypertension management.
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Heart Failure; Humans; Hypertension; Imidazoles; Losartan; Tetrazoles | 1997 |
Is there a rationale for combining angiotensin-converting enzyme inhibitors and calcium antagonists in cardiovascular disease?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Muscle, Smooth, Vascular; Myocardial Ischemia; Nitric Oxide | 1997 |
Targeting the genes of angiotensin receptors.
Topics: Angiotensin II; Animals; Gene Expression; Hypertension; Mice; Mice, Mutant Strains; Phenotype; Receptors, Angiotensin; Renal Artery | 1997 |
Intrarenal production of angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Hemodynamics; Humans; Hypertension; Kidney; Rats; Renin-Angiotensin System | 1997 |
Renin-angiotensin system: genes to bedside.
Topics: Angioplasty, Balloon, Coronary; Angiotensin II; Animals; Arteriosclerosis; Blood Pressure; Cardiomyopathy, Dilated; Cardiovascular Diseases; Constriction, Pathologic; Humans; Hypertension; Hypertrophy, Left Ventricular; Myocardial Infarction; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Recurrence; Renin-Angiotensin System | 1997 |
Do we need angiotensin II antagonists to treat hypertensive patients?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Tetrazoles | 1997 |
[Genetic dissection of protease and signal transduction network].
Topics: Angiotensin II; Angiotensinogen; Animals; Female; Humans; Hypertension; Mice; Mice, Knockout; Mice, Transgenic; Pregnancy; Renin-Angiotensin System; Risk Factors; Signal Transduction | 1997 |
[The renin-angiotensin system].
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Homeostasis; Humans; Hypertension; Renin-Angiotensin System; Sodium | 1997 |
[AT1 angiotensin receptor inhibition as a new therapeutic possibility].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Female; Heart Failure; Humans; Hypertension; Losartan; Renin-Angiotensin System | 1997 |
[Regression of left ventricular hypertrophy in hypertensive patients].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular | 1997 |
[The advent of a new class of antihypertensive agents: angiotensin II receptor antagonists].
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Cardiac Output, Low; Controlled Clinical Trials as Topic; Diuretics; Humans; Hypertension; Incidence; Losartan; Patient Compliance; Placebos; Sodium Chloride Symporter Inhibitors | 1997 |
Irbesartan. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in the management of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Hemodynamics; Humans; Hypertension; Irbesartan; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Tissue Distribution | 1997 |
Vasculoprotective and cardioprotective mechanisms of angiotensin-converting enzyme inhibition: the homeostatic balance between angiotensin II and nitric oxide.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Coronary Artery Disease; Hemodynamics; Homeostasis; Humans; Hypertension; Nitric Oxide | 1997 |
Endothelial function and bradykinin in humans.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Coronary Disease; Endothelium, Vascular; Humans; Hypertension; Myocardial Ischemia; Nitric Oxide; Renin-Angiotensin System | 1997 |
Regulation and role of myocardial collagen matrix remodeling in hypertensive heart disease.
Topics: Adult; Aldosterone; Angiotensin II; Animals; Cells, Cultured; Collagen; Collagenases; Heart; Heart Diseases; Humans; Hypertension; Matrix Metalloproteinase 1; Myocardium; Renin-Angiotensin System; Transcription, Genetic | 1997 |
[Current therapy: losartan].
Topics: Angiotensin II; Antihypertensive Agents; Drug Costs; Humans; Hypertension; Losartan; Renin-Angiotensin System | 1997 |
Arthur C. Corcoran Memorial Lecture. The role of eicosanoids in angiotensin-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Eicosanoids; Humans; Hypertension; Kidney; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Rats | 1998 |
Involvement of angiotensin II in cardiovascular and renal injury: effects of an AT1-receptor antagonist on gene expression and the cellular phenotype.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Fibronectins; Gene Expression; Humans; Hypertension; Nephrosclerosis; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles | 1997 |
Left ventricular hypertrophy in hypertension: etiology, treatment, and controversies.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Risk Factors | 1998 |
Vascular hypertrophy in hypertension: role of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Cell Division; Humans; Hypertension; Hypertrophy; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 1998 |
The renin-angiotensin system as a mediator of renal injury in hypertension.
Topics: Angiotensin II; Animals; Endothelin-1; Hemodynamics; Humans; Hypertension; Kidney; Nephrosclerosis; Renin-Angiotensin System | 1998 |
The impact of angiotensin converting enzyme inhibitors on the arterial wall.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Endothelium, Vascular; Humans; Hyperlipidemias; Hypertension; Sympathetic Nervous System; Vascular Diseases | 1996 |
Clinical pharmacokinetics of vasodilators. Part I.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biological Availability; Calcium Channel Blockers; Half-Life; Humans; Hypertension; Potassium Channels; Vasodilation; Vasodilator Agents | 1998 |
Current recommendations for initial therapy in hypertension: are they still valid? Introduction.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Practice Guidelines as Topic | 1998 |
The role of combination therapy in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Practice Guidelines as Topic | 1998 |
Molecular and cellular mechanisms of action of angiotensin II (AT1) receptors in vascular smooth muscle.
Topics: Angiotensin II; Animals; Cells, Cultured; Humans; Hypertension; Ion Channels; Muscle, Smooth, Vascular; Protein Kinase C; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Type C Phospholipases; Vasoconstriction | 1998 |
The potential role of angiotensin II in the vasculature.
Topics: Angiotensin II; Animals; Arteries; Humans; Hypertension; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Neovascularization, Physiologic; Rabbits; Receptors, Angiotensin; Renin-Angiotensin System; Vascular Resistance | 1998 |
Bioactive angiotensin peptides.
Topics: Angiotensin II; Angiotensin III; Animals; Blood Pressure; Humans; Hypertension; Peptide Fragments; Peptides; Renin-Angiotensin System; Sensitivity and Specificity | 1998 |
The importance of the renin-angiotensin system in cardiovascular disease.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Diabetic Nephropathies; Heart Failure; Humans; Hypertension; Renin-Angiotensin System; Sensitivity and Specificity | 1998 |
Receptors and their classification: focus on angiotensin II and the AT2 receptor.
Topics: Angiotensin II; Animals; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sensitivity and Specificity; Signal Transduction | 1998 |
Angiotensin, LDL peroxidation and atherosclerosis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Dose-Response Relationship, Drug; Humans; Hypertension; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Mice; Receptors, LDL | 1998 |
[Pharmacokinetic and pharmacodynamic aspects of angiotensin II antagonists. Focus on arterial hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Hypertension; Vasoconstrictor Agents | 1998 |
[Functional role of angiotensin II predicted from the phenotypes of transgenic and knockout mice].
Topics: Angiotensin II; Animals; Arteriosclerosis; Hypertension; Mice; Mice, Knockout; Mice, Transgenic; Phenotype; Renin-Angiotensin System | 1998 |
The TGR(mRen2)27 transgenic rat model of hypertension.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Disease Models, Animal; Gene Expression; Hypertension; Kidney; Myocardium; Phenotype; Rats; Renin-Angiotensin System | 1998 |
Angiotensin II receptor antagonists and treatment of hypertension and renal disease.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hypertension; Kidney Diseases | 1998 |
[New prospects in the treatment of arterial hypertension. Antagonist of angiotensin II valsartan (diovan)].
Topics: Angiotensin II; Antihypertensive Agents; Humans; Hypertension; Safety; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
The pathophysiology of hypertension: the importance of angiotensin II in cardiovascular remodeling.
Topics: Angiotensin II; Animals; Arteriosclerosis; Cardiovascular Diseases; Humans; Hypertension; Kidney Diseases; Renin-Angiotensin System | 1998 |
Overview of angiotensin II-receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Heart Failure; Humans; Hypertension; Renin-Angiotensin System | 1998 |
Gene therapy for hypertension: antisense inhibition with adeno-associated viral vector delivery targeting angiotensin II type 1-receptor messenger ribonucleic acid.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dependovirus; Genetic Therapy; Genetic Vectors; Hypertension; Oligonucleotides, Antisense; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger | 1998 |
Endothelin in hypertension: a role for receptor antagonists?
Topics: Angiotensin II; Animals; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Diseases; Rats; Vascular Diseases; Vasoconstrictor Agents | 1998 |
Antihypertensive effects of angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Hypertension; Peptide Fragments; Renin-Angiotensin System | 1998 |
Angiotensin II in central nervous system physiology.
Topics: Angiotensin II; Brain; Cardiovascular Physiological Phenomena; Central Nervous System; Hypertension; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 1998 |
Angiotensin blocking drugs and the heart beyond 2000.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Cardiomegaly; Forecasting; Hypertension; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 1999 |
Hypertension-induced end-organ damage : A new transgenic approach to an old problem.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Coronary Circulation; Humans; Hypertension; Kidney; Models, Cardiovascular; Myocardium; Rats; Renal Circulation; Renin | 1999 |
The renin-angiotensin system and its receptors.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular Diseases; Cell Division; Humans; Hypertension; Kidney Diseases; Receptors, Angiotensin; Renin-Angiotensin System; Salts; Water | 1999 |
Valsartan and the kidney: present and future.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Humans; Hypertension; Kidney Diseases; Renal Insufficiency; Tetrazoles; Valine; Valsartan | 1999 |
Angiotensin II receptor pharmacology and AT1-receptor blockers.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiophenes | 1999 |
Role of tissue angiotensin II in myocardial remodelling induced by mechanical stress.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hydralazine; Hypertension; Myocardium; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stress, Mechanical; Tetrazoles; Ventricular Remodeling | 1999 |
Pharmacologic properties of candesartan cilexetil--possible mechanisms of long-acting antihypertensive action.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1999 |
[Mechanisms of action of angiotensin II].
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Kidney Diseases; Receptors, Angiotensin; Reference Values; Renin-Angiotensin System; Transcription Factors | 1998 |
The benefits of angiotensin II receptor blockers in patients with renal insufficiency or failure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Disease Models, Animal; Humans; Hypertension; Losartan; Rats; Renal Insufficiency; Renin-Angiotensin System; Treatment Outcome | 1998 |
[The role of neurohormonal mechanisms in the etiopathogenesis of essential hypertension].
Topics: Aldosterone; Angiotensin II; Endothelins; Humans; Hypertension; Neuropeptide Y; Nitric Oxide; Renin; Vasopressins | 1998 |
Angiotensin II and long-term arterial pressure regulation: the overriding dominance of the kidney.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Natriuresis; Renal Circulation; Renin-Angiotensin System | 1999 |
Angiotensin receptor blockers: pharmacology and clinical significance.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypertension; Rats; Receptors, Angiotensin; Renal Circulation | 1999 |
Comparative antihypertensive effects of angiotensin II receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypertension | 1999 |
The role of corticosteriods in the regulation of vascular tone.
Topics: Adrenal Cortex Hormones; Angiotensin II; Animals; Glucocorticoids; Humans; Hypertension; Mineralocorticoids; Muscle, Smooth, Vascular; Receptors, Angiotensin; Signal Transduction; Vasoconstriction | 1999 |
[Hypertension and vasoactive substances].
Topics: Adrenomedullin; Angiotensin II; Atrial Natriuretic Factor; Catecholamines; Endothelins; Humans; Hypertension; Nitric Oxide; Peptides | 1999 |
Practical considerations of the pharmacology of angiotensin receptor blockers.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Heart Failure; Humans; Hypertension | 1999 |
[Therapy of arterial hypertension with angiotensin receptor blockers].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Humans; Hypertension | 1999 |
Seven lessons from two candidate genes in human essential hypertension: angiotensinogen and epithelial sodium channel.
Topics: Angiotensin II; Angiotensinogen; Animals; Diet; Diet, Sodium-Restricted; Epithelial Sodium Channels; Genetic Variation; Genotype; Humans; Hypertension; Rats; Renal Circulation; Sodium Channels | 1999 |
[Hypertension therapy and molecular biology--with special reference to renin-angiotensin system].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension | 1999 |
Angiotensin and cerebral blood flow.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cerebrovascular Circulation; Cerebrovascular Disorders; Homeostasis; Humans; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles | 1999 |
[Molecular structure of renin-angiotensin-aldosterone system].
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Electrolytes; Gene Expression; Genetic Linkage; Humans; Hypertension; Renin; RNA, Messenger | 1999 |
Angiotensin-II receptor antagonists: their place in therapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan | 1999 |
The molecular mechanism of cardiac hypertrophy and failure.
Topics: Angiotensin II; Animals; Cardiac Output, Low; Cardiomegaly; Endothelin-1; Hypertension; Myocardium; Renin-Angiotensin System; Signal Transduction; Sodium-Hydrogen Exchangers; Stress, Mechanical | 1999 |
Role for NADPH/NADH oxidase in the modulation of vascular tone.
Topics: Angiotensin II; Animals; Blood Vessels; Humans; Hypertension; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADP; Neutrophils; Nitric Oxide; Superoxides; Vasomotor System | 1999 |
Non-peptide angiotensin type 1 receptor antagonists in the treatment of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Losartan | 1999 |
Regulation of blood pressure in chronic renal failure: determinants of hypertension and dialysis-related hypotension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Baroreflex; Blood Volume; Female; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Hypotension; Kidney Failure, Chronic; Male; Renal Dialysis; Sympathetic Nervous System | 1999 |
Hypertension as a paraneoplastic syndrome in hepatocellular carcinoma.
Topics: Aged; Angiotensin I; Angiotensin II; Carcinoma, Hepatocellular; Fatal Outcome; Humans; Hypertension; Hypoglycemia; Liver Neoplasms; Male; Paraneoplastic Syndromes; Renin; Tomography, X-Ray Computed; Ultrasonography | 1999 |
Safety and efficacy of eprosartan, a new angiotensin II receptor blocker.
Topics: Acrylates; Angiotensin II; Antihypertensive Agents; Cardiovascular Diseases; Drug Interactions; Humans; Hypertension; Imidazoles; Thiophenes | 1999 |
Pharmacology of eprosartan, an angiotensin II receptor antagonist: exploring hypotheses from clinical data.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Disease Models, Animal; Humans; Hypertension; Imidazoles; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes | 1999 |
[New concepts in the pathogenesis of essential hypertension].
Topics: Adult; Angiotensin II; Child; Diabetes Mellitus, Type 1; Endothelin-1; Humans; Hypertension; Nitric Oxide; Obesity; Poland; Risk Factors; Sodium, Dietary | 1999 |
Modulation and function of extrarenal angiotensin receptors.
Topics: Adrenal Glands; Angiotensin II; Animals; Gene Expression Regulation; Humans; Hypertension; Muscle, Smooth, Vascular; ras Proteins; Receptors, Angiotensin; Reference Values; Renin-Angiotensin System; Sodium, Dietary; Transcription, Genetic | 1999 |
Angiotensin II receptor antagonists in the treatment of hypertension.
Topics: Algorithms; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Receptors, Angiotensin; Telmisartan; Tetrazoles; Valine; Valsartan | 1999 |
State-of-the-Art lecture. Role of angiotensin and oxidative stress in essential hypertension.
Topics: Angiotensin II; Animals; Dinoprost; Humans; Hypertension; Nitric Oxide; Oxidative Stress | 1999 |
Aldosterone and the heart: towards a physiological function?
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Fibrosis; Gene Expression; Humans; Hypertension; Ion Transport; Myocardium; Receptors, Angiotensin; Receptors, Mineralocorticoid | 1999 |
Renin angiotensin system antagonists and anesthesia.
Topics: Anesthesia; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Heart Diseases; Hemodynamics; Humans; Hypertension; Kidney; Receptors, Angiotensin; Renin-Angiotensin System | 1999 |
Angiotensin II receptor blockers: review of the binding characteristics.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction | 1999 |
Long-term benefits of angiotensin II blockade: is the consensus changing?
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diuretics; Humans; Hypertension; Meta-Analysis as Topic; Renin-Angiotensin System | 1999 |
Emerging treatments for hypertension: potential role for vasopeptidase inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Blood Pressure; Heart Failure; Humans; Hypertension; Pyridines; Renin; Survival Rate; Thiazepines; Treatment Outcome; Vasodilation | 1999 |
Captopril prevention project--what shall we do about captopril and the risk of stroke?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Brain Ischemia; Captopril; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stroke | 2000 |
[Apoptosis in hypertensive cardiopathy].
Topics: Adult; Angiotensin II; Animals; Apoptosis; Cardiomyopathies; Heart Diseases; Humans; Hypertension; Hypertrophy, Left Ventricular; Insulin-Like Growth Factor I; Middle Aged; Myocardium; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tumor Suppressor Protein p53 | 1999 |
[Antihypertensive advantages of angiotensin II AT1 receptor antagonism].
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Heart Diseases; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 1999 |
The renin-angiotensin-aldosterone system: a specific target for hypertension management.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System; Vasoconstriction | 1999 |
Angiotensin II receptor blockade and end-organ protection.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Glomerular Filtration Rate; Heart Failure; Humans; Hypertension; Myocardial Contraction; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium; Vascular Diseases | 1999 |
Diabetes and hypertension: blood pressure control and consequences.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Humans; Hypertension; Kidney Failure, Chronic; Myocardial Contraction | 1999 |
Angiotensin II type 1 receptor blockade: a new development in cardiovascular pharmacology.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Cardiovascular System; Heart Failure; Humans; Hypertension; Losartan; Receptors, Angiotensin; Renin-Angiotensin System | 1998 |
[Pathophysiological roles of chymase and effects of chymase inhibitor].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Chymases; Chymotrypsin; Cricetinae; Dogs; Enzyme Inhibitors; Humans; Hypertension; Neovascularization, Physiologic; Oligopeptides; Rats; Serine Endopeptidases; Serine Proteinase Inhibitors; Species Specificity; Vasoconstriction | 1999 |
Candesartan cilexetil: an angiotensin II receptor blocker.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Tetrazoles | 1999 |
Is there an advantage to combination therapy with ACE inhibitors and angiotensin II-receptor blockers?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hypertension; Losartan | 2000 |
Na+/H+ exchange hyperactivity and myocardial hypertrophy: are they linked phenomena?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antiporters; Cardiomegaly; Erythrocytes; Humans; Hydrogen-Ion Concentration; Hypertension; Myocardium; Signal Transduction; Sodium-Hydrogen Exchangers | 1999 |
Interactions among ACE, kinins and NO.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Biological Availability; Cardiovascular Diseases; Endothelium, Vascular; Humans; Hypertension; Kinins; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Ventricular Remodeling | 1999 |
Nitric oxide-angiotensin II interactions in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Arterioles; Enzyme Inhibitors; Hypertension; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Renal Circulation | 2000 |
[Do angiotensin II receptor antagonists substitute angiotensin converting enzyme inhibitors in the treatment of high blood pressure?].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Diabetic Angiopathies; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Vasoconstriction | 2000 |
Role of the renin-angiotensin system in cardiac hypertrophy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Cell Division; Cells, Cultured; Hydralazine; Hypertension; Mitogen-Activated Protein Kinases; Myocardium; Protein-Tyrosine Kinases; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction; Sodium-Hydrogen Exchangers; Tetrazoles | 1999 |
Role of angiotensin AT1, and AT2 receptors in cardiac hypertrophy and disease.
Topics: Angiotensin II; Animals; Aortic Valve Stenosis; Cardiomegaly; Cell Division; Humans; Hypertension; Myocardium; Proto-Oncogene Mas; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction | 1999 |
Hypertension, small arteries, and pathways for angiotensin II generation: "The proper study of mankind is man".
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arteries; Humans; Hypertension | 2000 |
Candesartan cilexetil: an angiotensin II-receptor blocker.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Prodrugs; Randomized Controlled Trials as Topic; Tetrazoles | 2000 |
[Angiotensin II antagonist receptors].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Receptors, Angiotensin | 2000 |
[Renal protection with antagonists of the angiotensin II receptors].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Kidney; Receptors, Angiotensin; Renal Circulation; Renin; Vasodilation | 2000 |
[Left ventricular hypertrophy regression in arterial hypertension. The efficacy of the angiotensin II type 1 receptor antagonists].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Echocardiography; Humans; Hypertension; Hypertrophy, Left Ventricular; Receptors, Angiotensin; Risk Factors; Treatment Outcome | 2000 |
Angiotensin II antagonists for hypertension: are there differences in efficacy?
Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2000 |
Emerging concepts in antihypertensive therapy: the benefits of angiotensin II blockade.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apoptosis; Humans; Hypertension; Myocardium; Receptors, Angiotensin; Renin-Angiotensin System; Risk Assessment; Signal Transduction | 1999 |
Oxidative stress may explain how hypertension is maintained by normal levels of angiotensin II.
Topics: Angiotensin II; Animals; Endothelins; Extracellular Space; Hypertension; Nitric Oxide; Oxidative Stress; Receptors, Prostaglandin; Renin; Sodium Chloride; Swine | 2000 |
Review of the Y chromosome and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Collagen; Coronary Vessels; Female; Heat-Shock Proteins; Humans; Hypertension; Kidney; Male; Norepinephrine; Polymorphism, Genetic; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride; Sympathetic Nervous System; Testosterone; Y Chromosome | 2000 |
[A role of angiotensin II found in knockout mice with angiotensin signal breakdown].
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cardiovascular Diseases; Humans; Hypertension; Mice; Mice, Knockout; Nerve Regeneration; Renin-Angiotensin System; Risk Factors | 2000 |
Using angiotensin converting enzyme inhibitors in African-American hypertensives: a new approach to treating hypertension and preventing target-organ damage.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Black People; Dose-Response Relationship, Drug; Female; Heart Diseases; Humans; Hypertension; Kidney Failure, Chronic; Male; United States | 2000 |
Factors affecting circadian variability.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cardiovascular Diseases; Circadian Rhythm; Humans; Hypertension; Receptors, Angiotensin; Renin-Angiotensin System; Vasoconstrictor Agents | 2000 |
Angiotensin receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles | 2000 |
[Use of angiotensin-II-antagonists in hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Hypertension; Losartan; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan | 2000 |
Theoretical basis and clinical evidence for differential effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor subtype 1 blockers.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiovascular Diseases; Hemodynamics; Humans; Hypertension; Kidney Diseases; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Renin-Angiotensin System | 2000 |
Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood pressure.
Topics: Aminopeptidases; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arteries; Binding Sites; Blood Pressure; Brain; CD13 Antigens; Dose-Response Relationship, Drug; Glutamyl Aminopeptidase; Hypertension; Hypothalamus; Losartan; Mice; Models, Chemical; Mutagenesis, Site-Directed; Peptides; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Thermolysin; Vasopressins | 2000 |
Plasma endothelin levels: a meaningless number?
Topics: Adaptation, Physiological; Angioplasty; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cold Temperature; Endothelin-1; Humans; Hypertension; Hypoxia; Kidney; Renal Artery Obstruction; Renin-Angiotensin System; Sympathetic Nervous System | 2000 |
Endothelin: role in experimental hypertension.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Fructose; Hypertension; Insulin Resistance; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Dahl; Rats, Inbred SHR | 2000 |
Oxidative stress and vascular damage in hypertension.
Topics: Angiotensin II; Endothelium, Vascular; Free Radicals; Humans; Hypertension; Oxidative Stress; Superoxide Dismutase | 2000 |
Fat cell metabolism: insulin, fatty acids, and renin.
Topics: Adipocytes; Angiotensin II; Animals; Fatty Acids; Humans; Hypertension; Insulin; Insulin Resistance; Obesity; Renin; Risk Factors | 2000 |
Prospective trials of angiotensin receptor blockers: beyond blood pressure control.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Losartan; Myocardial Infarction; Tetrazoles; Valine; Valsartan | 2000 |
Free radical production and angiotensin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Free Radicals; Humans; Hypertension; NADPH Oxidases; Nitric Oxide; Reactive Oxygen Species; Receptors, Angiotensin; Risk Factors; Signal Transduction; Up-Regulation | 2000 |
Hypertension-induced organ damage in African Americans: transforming growth factor-beta(1) excess as a mechanism for increased prevalence.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Black People; Coronary Disease; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Linear Models; Prevalence; Stroke; Transforming Growth Factor beta; White People | 2000 |
Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways.
Topics: Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Humans; Hypertension; Mice; Mice, Knockout; Mice, Transgenic; Nitric Oxide; Peptidyl-Dipeptidase A; Receptors, Dopamine; Receptors, Neuropeptide; Renin-Angiotensin System | 2000 |
Treatment of hypertension in diabetes mellitus.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Hypertension; Kidney Diseases; Myocardial Infarction; Placebos; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors | 2000 |
Treating high-risk diabetic hypertensive patients with comorbid conditions.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Disease Progression; Humans; Hypertension; Kidney Failure, Chronic; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors | 2000 |
Impact of angiotensin II on the kidney: does an angiotensin II receptor blocker make sense?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blood Volume; Clinical Trials as Topic; Diabetes Mellitus; Disease Progression; Glomerulosclerosis, Focal Segmental; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Proteinuria; Renin-Angiotensin System; Vasodilator Agents; Water-Electrolyte Balance | 2000 |
Rationale for angiotensin II receptor blockers in patients with low-renin hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black or African American; Black People; Blood Pressure; Blood Volume; Calcium Channel Blockers; Diet, Sodium-Restricted; Diuretics; Ethnicity; Humans; Hypertension; Ramipril; Renin; Risk Factors; United States | 2000 |
Renal mechanisms of angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Autocrine Communication; Blood Pressure; Glomerular Filtration Rate; Humans; Hypertension; Natriuresis; Paracrine Communication; Receptors, Angiotensin; Renal Circulation; Renin-Angiotensin System; Vascular Resistance | 2000 |
[Hypertension and reactive oxygen species].
Topics: Angiotensin II; Animals; Calcium Channel Blockers; Humans; Hypertension; Reactive Oxygen Species | 2000 |
[Control of renal hemodynamics by cytochrome P450-dependent metabolites of arachidonic acid].
Topics: Angiotensin II; Animals; Cytochrome P-450 Enzyme System; Eicosanoids; Humans; Hypertension; Nitric Oxide | 2000 |
Endothelial dysfunction in hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine; Clinical Trials as Topic; Endothelin-1; Endothelins; Endothelium, Vascular; Free Radicals; Humans; Hypertension; Nitric Oxide; Rats; Rats, Inbred SHR; Research; Risk Factors; Vasodilation | 2000 |
[The renin-angiotensin system and hypertension--the summary of the 20th century and expectation on the 21st century].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Renin-Angiotensin System | 2000 |
Angiotensin II type 1 receptor blockade: a novel therapeutic concept.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2000 |
Angiotensin II mediated signal transduction. Important role of tyrosine kinases.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Humans; Hypertension; Kidney Diseases; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Renin-Angiotensin System; Signal Transduction | 2000 |
Endothelin, renal diseases, and hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Endothelin-1; Endothelins; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Nitric Oxide | 2000 |
[The role of angiotensin II receptors in the pathogenesis and treatment of hypertension].
Topics: Angiotensin II; Humans; Hypertension; Receptors, Angiotensin | 1999 |
The role of angiotensin II receptor antagonists in hypertension management: focus on candesartan cilexetil.
Topics: Adult; Age Factors; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Hypertension; Life Style; Male; Middle Aged; Patient Compliance; Practice Guidelines as Topic; Prevalence; Prodrugs; Prospective Studies; Risk; Risk Factors; Sex Factors; Tetrazoles; Time Factors; World Health Organization | 2000 |
Blocking the tissue renin-angiotensin system: the future cornerstone of therapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiovascular System; Dogs; Heart; Humans; Hypertension; In Vitro Techniques; Kidney; Prodrugs; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Time Factors | 2000 |
Putting the efficacy of candesartan cilexetil into perspective: a review of new comparative data.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cattle; Cerebellum; Circadian Rhythm; Female; Heart; Humans; Hypertension; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Middle Aged; Prodrugs; Rabbits; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin; Tetrazoles; Time Factors | 2000 |
Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Humans; Hypertension; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein-Tyrosine Kinases; Receptors, Angiotensin; Signal Transduction | 2000 |
Current genetics of essential hypertension.
Topics: Angiotensin II; Angiotensinogen; Humans; Hypertension; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
Angiotensin, inflammation, hypertension, and cardiovascular disease.
Topics: Angiotensin II; Cardiovascular Diseases; Humans; Hypertension; Inflammation; NF-kappa B; Vasoconstrictor Agents | 2001 |
Angiotensinogen in essential hypertension: from genetics to nephrology.
Topics: Alleles; Angiotensin II; Angiotensinogen; Female; Genetic Linkage; Genetic Variation; Haplotypes; Homeostasis; Humans; Hypertension; Japan; Male; Models, Genetic; Nephrons; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Promoter Regions, Genetic; Renin-Angiotensin System | 2001 |
[Prospects for pharmacological effects on renin-angiotensin and sympathetic nervous systems in patients with arterial hypertension].
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes | 2000 |
Oxidative stress and vascular damage in hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Vessels; Cardiovascular Diseases; Disease Models, Animal; Estrogens; Gene Transfer Techniques; Humans; Hydrogen Peroxide; Hypertension; Mitochondria; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitrates; Nitric Oxide Synthase; Oxidative Stress; Rats; Reactive Oxygen Species; Renin-Angiotensin System; Risk Factors; Signal Transduction; Superoxide Dismutase; Vitamins; Xanthine Oxidase | 2001 |
The future of hypertension therapy: sense, antisense, or nonsense?
Topics: Adenoviridae; Adrenomedullin; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Animal; DNA, Antisense; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; HIV; Humans; Hypertension; Kallikreins; Luminescent Proteins; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptides; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retroviridae; Transfection | 2001 |
Workshop: hypertension and cardiovascular risk factors: role of the angiotensin II-nitric oxide interaction.
Topics: Albuminuria; Angiotensin II; Animals; Cardiovascular Diseases; Diabetes Complications; Endothelium, Vascular; Homeostasis; Humans; Hypertension; Nitric Oxide; Nitric Oxide Synthase; Renin-Angiotensin System; Risk Factors; Superoxides | 2001 |
Left ventricular hypertrophy and angiotensin II antagonists.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Hormone Antagonists; Humans; Hypertension; Hypertrophy, Left Ventricular; Renin-Angiotensin System | 2001 |
Valsartan: a novel angiotensin type 1 receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Clinical Trials as Topic; Heart Failure; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan | 2000 |
Symposium on the etiology of hypertension--summarizing studies in 20th century. 5. Renin-angiotensin system and hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; CD36 Antigens; Gene Expression Regulation; Humans; Hypertension; Kidney; Lipoproteins, LDL; Nephrectomy; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, LDL; Receptors, Oxidized LDL; Renin; Renin-Angiotensin System; Scavenger Receptors, Class E; Signal Transduction; Superoxides; Transcription Factors | 2001 |
Angiotensin receptor blockers and the kidney: possible advantages over ACE inhibition?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus; Disease Models, Animal; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Failure, Chronic; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2001 |
Angiotensin II-receptor blockers: clinical relevance and therapeutic role.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Diabetic Neuropathies; Heart Failure; Humans; Hypertension | 2001 |
Angiotensin II and the pathophysiology of cardiovascular remodeling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Humans; Hypertension; Renin-Angiotensin System; Transforming Growth Factor beta | 2001 |
Medical management of mild-to-moderate heart failure before the advent of beta blockers.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anticoagulants; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Heart Failure; Humans; Hypertension; Isosorbide Dinitrate; Randomized Controlled Trials as Topic; Severity of Illness Index; Vasodilator Agents | 2001 |
Role of hypertension in the progression of chronic renal disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Black or African American; Black People; Chronic Disease; Disease Progression; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Muscle, Smooth, Vascular; United States | 2001 |
[Cardiovascular abnormalities as a cause of hypertension].
Topics: Adrenomedullin; Angiotensin II; Animals; Cardiovascular System; Catecholamines; Cell Division; Endothelin-1; Humans; Hypertension; Insulin; Kallikrein-Kinin System; Muscle, Smooth, Vascular; Natriuretic Agents; Nitric Oxide; Peptides; Vasoconstriction | 2001 |
Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Heart Failure; Humans; Hypertension; Losartan; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Spironolactone; Tetrazoles; Valine; Valsartan | 2001 |
Local angiotensin II-generating system in vascular tissues: the roles of chymase.
Topics: Angiotensin II; Animals; Arteries; Chymases; Humans; Hypertension; Serine Endopeptidases | 2001 |
Arterial pressure control at the onset of type I diabetes: the role of nitric oxide and the renin-angiotensin system.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Humans; Hypertension; Kidney; Nitric Oxide; Renin-Angiotensin System | 2001 |
[Clinical pharmacology of angiotensin II receptor antagonists].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Receptors, Angiotensin | 2001 |
[Angiotensin II type-1-receptor antagonists from the viewpoint of nephrology].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Therapeutic Equivalency | 2001 |
Clinical potential: angiotensin converting enzyme inhibitor or angiotensin II antagonist?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Myocardial Infarction; Renal Insufficiency; Renin-Angiotensin System | 2001 |
Pharmacology and clinical efficacy of angiotensin receptor blockers.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes; Treatment Outcome | 2001 |
Angiotensin converting enzyme inhibition and the kidney.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Dogs; Humans; Hypertension; Hypertension, Renovascular; Kidney; Kidney Diseases; Renal Circulation; Renin-Angiotensin System; Sodium, Dietary | 1988 |
Sodium sensitive hypertension: renal and adrenal non-modulation in its pathogenesis.
Topics: Adrenal Glands; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Kidney; Renal Circulation; Renin; Renin-Angiotensin System; Sodium, Dietary; Vasodilation | 1988 |
Telmisartan: a review of its use in hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Drug Interactions; Heart Failure; Humans; Hypertension; Randomized Controlled Trials as Topic; Telmisartan; Treatment Outcome | 2001 |
Intrarenal transport and vasoactive substances in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biological Transport; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY | 2001 |
[Pathogenesis of arterial hypertension in the Itsenko-Cushing syndrome].
Topics: Angiotensin II; Cushing Syndrome; Glucocorticoids; Humans; Hypertension; Peptidyl-Dipeptidase A | 2001 |
[Resistance to ACE inhibitors. Myth or reality?].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Drug Resistance; Humans; Hypertension; Renin-Angiotensin System; Ventricular Remodeling | 2001 |
[Isolated systolic hypertension in the elderly].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Humans; Hypertension; Prevalence; Risk Factors; Systole | 2001 |
Oxidative stress in arterial hypertension: role of NAD(P)H oxidase.
Topics: Angiotensin II; Animals; Genetic Predisposition to Disease; Humans; Hypertension; Hypertension, Renovascular; Muscle, Smooth, Vascular; NADPH Oxidases; Oxidative Stress; Stress, Mechanical; Up-Regulation | 2001 |
Cardiomyocyte apoptotic cell death in arterial hypertension: mechanisms and potential management.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Humans; Hypertension; Myocardium; Stress, Mechanical; Ventricular Remodeling | 2001 |
Genetic determinants of vascular reactivity.
Topics: Angiotensin II; Blood Pressure; Blood Vessels; Cardiovascular Diseases; Endothelin-1; Endothelins; Genotype; Humans; Hypertension; Nitric Oxide Synthase; Polymorphism, Genetic; Protein Precursors; Renin-Angiotensin System | 2002 |
[Angiotensin II antagonists versus ACE inhibitors in the treatment of raised blood pressure].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Renin-Angiotensin System; Risk Factors | 2001 |
Angiotensin II antagonists in systolic blood pressure control.
Topics: Acrylates; Angiotensin II; Antihypertensive Agents; Blood Pressure; Delivery of Health Care; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Systole; Thiophenes | 2001 |
The hypertension-lipid connection: insights into the relation between angiotensin II and cholesterol in atherogenesis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arteriosclerosis; Cholesterol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2002 |
Improving the managed care of hypertension with angiotensin II antagonists.
Topics: Angiotensin II; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Managed Care Programs; Renin-Angiotensin System | 2002 |
Use of angiotensin II receptor blockers in animal models of atherosclerosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteriosclerosis; Cholesterol, LDL; Disease Models, Animal; Endothelium, Vascular; Hypertension; Nitric Oxide; Renin-Angiotensin System | 2002 |
Angiotensin II receptor blockers for the treatment of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Clinical Trials as Topic; Humans; Hypertension; Receptor, Angiotensin, Type 1 | 2001 |
Pharmacological properties of angiotensin II antagonists: examining all the therapeutic implications.
Topics: Angiotensin II; Animals; Humans; Hypertension; Renin-Angiotensin System | 2001 |
Regulation of intrarenal angiotensin II in hypertension.
Topics: Angiotensin II; Angiotensinogen; Humans; Hypertension; Kidney; Kidney Tubules; Receptors, Angiotensin | 2002 |
Dual angiotensin II blockade: a promise of enhanced renal protection?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Synergism; Humans; Hypertension; Kidney Diseases; Proteinuria; Receptor, Angiotensin, Type 1; Tetrazoles | 2002 |
The new oral angiotensin II antagonist olmesartan medoxomil: a concise overview.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Olmesartan Medoxomil; Tetrazoles | 2002 |
Dopamine, hypertension and obesity.
Topics: Angiotensin II; Animals; Dopamine; Dopamine Agonists; Humans; Hypertension; Nitric Oxide; Obesity; Protein Kinase C; Rats; Receptors, Dopamine; Risk Factors; Sodium-Hydrogen Exchangers; Vasopressins | 2002 |
Candesartan cilexetil: an update of its use in essential hypertension.
Topics: Adsorption; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Black People; Diabetes Mellitus, Type 2; Drug Interactions; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney; Renal Insufficiency; Tetrazoles; Treatment Outcome | 2002 |
[Angiotensin II receptor blockers: current status and future prospects].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Drug Therapy, Combination; Heart Diseases; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2002 |
[Results from the LIFE study: promising effects of new hypertensive agents].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Atenolol; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome | 2002 |
Blockade of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiovascular Diseases; Diabetic Nephropathies; Humans; Hypertension; Receptors, Angiotensin; Renin-Angiotensin System | 2002 |
[Beta receptor blockaders in the treatment of hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Pressoreceptors; Propranolol; Renin | 1976 |
Pathophysiology of propranolol in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Diuretics; Hemodynamics; Homeostasis; Humans; Hypertension; Male; Middle Aged; Nervous System; Pressoreceptors; Propranolol; Renin; Sympathetic Nervous System; Vascular Resistance; Vasodilator Agents | 1977 |
Beta-adrenergic blockade in hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angiotensin II; Animals; Brain; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Kidney Function Tests; Practolol; Propranolol; Renin | 1977 |
Clinical pharmacology of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blood Pressure; Clonidine; Diazoxide; Diuretics; Emergencies; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Prazosin; Propranolol; Renin; Reserpine; Sympathetic Nervous System; Trimethaphan | 1977 |
Antihypertensive drugs: clinical pharmacology and therapeutic use.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Potassium; Prazosin; Secologanin Tryptamine Alkaloids; Sympatholytics | 1977 |
[Pharmacologic functional examination in arterial hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Blood Pressure; Diagnosis, Differential; Diuretics; Ferricyanides; Furosemide; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Nitroprusside; Oligopeptides; Pheochromocytoma; Propranolol; Renal Veins; Renin; Saralasin; Stimulation, Chemical; Teprotide | 1977 |
Labetalol: a review of its pharmacology and therapeutic use in hypertension.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Ethanolamines; Half-Life; Hemodynamics; Humans; Hypertension; Labetalol; Pheochromocytoma; Renin; Respiration | 1978 |
[Therapy of hypertension. I. new antihypertensive agents, pharmacologic and pharmacokinetic bases. Beta-adrenergic blockers and blood pressure lowering].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Bradycardia; Cardiac Output; Catecholamines; Cats; Dogs; Humans; Hypertension; Kinetics; Myocardial Infarction; Norepinephrine; Pressoreceptors; Rabbits; Renin; Vascular Resistance | 1977 |
[New antihypertensive agents].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chemical Phenomena; Chemistry; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Labetalol; Minoxidil; Prazosin | 1979 |
Hypertension in pregnancy.
Topics: Angiotensin II; Animals; Blood Coagulation; Edema; Female; Hormones; Humans; Hypertension; Immunoglobulins; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Uterus | 1975 |
Captopril in the treatment of clinical hypertension and cardiac failure.
Topics: Administration, Oral; Angiotensin II; Blood Pressure; Captopril; Diuretics; Drug Therapy, Combination; Heart Failure; Humans; Hypertension; Hypertension, Renal; Hyponatremia; Kidney Failure, Chronic; Proline; Renal Artery Obstruction | 1979 |
Vascular reactivity to angiotensin II in human pregnancy.
Topics: Adolescent; Angiotensin II; Animals; Aspirin; Blood Pressure; Blood Volume; Dogs; Female; Haplorhini; Hemoglobin, Sickle; Hemoglobinopathies; Humans; Hypertension; Indomethacin; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Complications, Hematologic; Prostaglandin Antagonists; Prostaglandins E | 1978 |
Preclinical pharmacology of saralasin.
Topics: Adrenal Glands; Angiotensin II; Animals; Binding, Competitive; Biopharmaceutics; Cattle; Dogs; Half-Life; Haplorhini; Humans; Hypertension; In Vitro Techniques; Kidney; Macaca mulatta; Male; Mice; Muscle, Smooth; Rabbits; Rats; Reproduction; Saralasin | 1979 |
Role of hypertension in atherosclerosis and cardiovascular disease.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arteriosclerosis; Blood Platelets; Capillary Permeability; Cardiomegaly; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Death, Sudden; Endothelium; Histamine; Humans; Hypertension; Lipids; Lysosomes; Muscle, Smooth; Renin; Serotonin; Thrombosis | 1976 |
The renin-angiotensin-aldosterone system in parenchymal kidney disease.
Topics: Acute Kidney Injury; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood Pressure; Heparin; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Kidney Diseases; Nephrectomy; Posture; Potassium; Renal Dialysis; Renin; Sodium | 1975 |
Mineralocorticoid hormones.
Topics: Acid-Base Imbalance; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Desoxycorticosterone; Digestive System; Humans; Hyperaldosteronism; Hypertension; Kidney; Mineralocorticoids; Muscles; Potassium; Prostaglandins; Receptors, Cell Surface; Renin; Sodium | 1976 |
The adrenal cortex and essential hypertension.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Epinephrine; Humans; Hypertension; Liver; Middle Aged; Progesterone; Renin; Sodium; Stress, Physiological; Transcortin | 1976 |
Converting enzyme inhibition and blood pressure regulation.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dogs; Heart Failure; Homeostasis; Hypertension; Rats; Renal Artery; Renin; Sodium | 1976 |
Drug-induced hypertension: pathogenesis and management.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Antidepressive Agents, Tricyclic; Carbenoxolone; Clonidine; Contraceptives, Oral, Hormonal; Cortisone; Estrogens; Glycyrrhiza; Hemodynamics; Humans; Hypertension; Monoamine Oxidase Inhibitors; Plants, Medicinal; Progestins; Renin; Sodium; Sympathomimetics; Water | 1976 |
Experimental and clinical studies with converting enzyme inhibitor.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dogs; Female; Heart Rate; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Posture; Renal Veins; Renin; Sodium; Time Factors | 1976 |
The biochemistry of the renin-angiotensin system and its role in hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Cattle; Dogs; Endopeptidases; Humans; Hypertension; Peptidyl-Dipeptidase A; Rabbits; Rats; Renin; Swine | 1976 |
Converting enzyme, angiotensin II and hypertensive disease.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensins; Animals; Antibodies; Blood Pressure; Chemistry; Fluorescent Antibody Technique; Goats; History, 19th Century; History, 20th Century; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Rabbits; Renin; Saralasin; Sodium; Teprotide | 1978 |
[Use of specific angiotensin inhibitors in the diagnosis and treatment of arterial hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Humans; Hypertension; Hypertension, Renovascular; Infusions, Parenteral; Oligopeptides; Proline; Rabbits; Rats; Saralasin; Teprotide | 1979 |
Control of aldosterone secretion.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Dogs; Humans; Hyperaldosteronism; Hypertension; Pituitary Gland, Anterior; Potassium | 1979 |
Interrelations between various blood pressure regulatory systems and the mosaic theory of hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Brain; Humans; Hypertension; Hypertension, Renal; Muscle Contraction; Nervous System Physiological Phenomena; Peptidyl-Dipeptidase A; Phylogeny; Renin; Sodium; Structure-Activity Relationship | 1979 |
[Angiotensin II receptor (author's transl)].
Topics: Adrenal Cortex; Angiotensin II; Animals; Aorta; Hypertension; Muscle, Smooth, Vascular; Rabbits; Radioligand Assay; Rats; Receptors, Angiotensin; Receptors, Cell Surface | 1979 |
Renin-angiotensin system in hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Blood Pressure; Chemical Phenomena; Chemistry; Humans; Hypertension; Hypertension, Renal; Peptidyl-Dipeptidase A; Renin; Sodium | 1979 |
Renin-angiotensin system.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Amino Acid Sequence; Angiotensin II; Animals; Antibodies; Binding, Competitive; Blood Vessels; Central Nervous System; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney; Kidney Neoplasms; Peripheral Nerves; Radioimmunoassay; Renin; Thirst | 1975 |
Renal prostaglandins.
Topics: Alcohol Oxidoreductases; Angiotensin II; Animals; Arachidonic Acids; Biological Transport; Capillaries; Diuresis; Humans; Hypertension; Indomethacin; Kidney; Kidney Tubules, Proximal; Mixed Function Oxygenases; Natriuresis; Prostaglandins; Regional Blood Flow; Vasomotor System; Water-Electrolyte Balance | 1975 |
Renal vascular tone in essential and secondary hypertension: hemodynamic and angiographic responses to vasodilators.
Topics: Acetylcholine; Angiotensin II; Dopamine; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hypertension; Kidney; Phentolamine; Regional Blood Flow; Urography; Vascular Resistance; Vasodilator Agents | 1975 |
Prostaglandins and the kidney.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Anura; Chickens; Diuretics; Dogs; Erythropoiesis; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Failure, Chronic; Kidney Medulla; Kidney Tubules; Prostaglandins; Rabbits; Rats; Regional Blood Flow; Renin; Sodium; Water | 1977 |
The morphological basis for altered endothelial permeability in artherosclerosis.
Topics: Angiotensin II; Animals; Antigen-Antibody Complex; Arteries; Arteriosclerosis; Biogenic Amines; Carbon Monoxide; Cell Membrane Permeability; Cholesterol; Endothelium; Fatty Acids; Hypertension; Rheology | 1977 |
The renin-angiotensin system in the maternal and fetal circulation in pregnancy hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Delivery, Obstetric; Female; Fetal Blood; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1977 |
Experimental toxemia of pregnancy: review and speculation.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Dogs; Endocrine Glands; Female; Humans; Hypertension; Immunity; Ischemia; Kidney; Kidney Glomerulus; Liver; Placenta; Pre-Eclampsia; Pregnancy; Progesterone; Proteinuria; Rabbits; Rats; Renin; Uterus | 1977 |
Role of the adrenal cortex and sodium in the pathogenesis of human hypertension.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Animals; Dogs; Female; Humans; Hypertension; Kidney; Male; Models, Biological; Muscle Proteins; Muscle, Smooth; Norepinephrine; Prostaglandins; Rabbits; Rats; Sodium; Sodium Chloride; Vascular Resistance | 1978 |
[The effect of an angiotensin antagonist on blood pressure, renin and aldosterone secretion and its pathogenetic importance].
Topics: Aldosterone; Angiotensin II; Aortic Valve Stenosis; Bartter Syndrome; Binding, Competitive; Blood Pressure; Contraceptives, Oral; Humans; Hypertension; Hypertension, Renal; Renin; Saralasin | 1978 |
[Pathophysiological aspects of the renin-angiotensin-aldosterone system].
Topics: Adrenal Insufficiency; Aldosterone; Angiotensin II; Bartter Syndrome; Contraceptives, Oral; Half-Life; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Renin | 1977 |
Perspective on the physiology of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Body Water; Cardiac Output; Chemoreceptor Cells; Dogs; Heart; Humans; Hypertension; Kidney; Male; Mechanoreceptors; Rats; Reflex; Renin; Vascular Resistance; Vasopressins | 1978 |
Significance of renin and angiotensin in hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin I; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Neoplasms; Pregnancy; Pregnancy Complications, Cardiovascular; Renal Artery Obstruction; Renal Dialysis; Renin; Sodium | 1978 |
[The renin-angiotensin-aldosterone system in diabetics].
Topics: Aldosterone; Angiotensin II; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Humans; Hypertension; Kidney; Renin | 1978 |
Drug therapy of hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Evaluation; Humans; Hypertension; Prazosin; Propranolol; Sympathetic Nervous System; Vasodilator Agents | 1978 |
Kallikrein, kininogen and kinins in control of blood pressure.
Topics: Angiotensin II; Animals; Bartter Syndrome; Blood Pressure; Dogs; Humans; Hypertension; Hypotension; Kallikreins; Kidney; Kininogens; Kinins; Norepinephrine; Renin; Sodium | 1979 |
Aging and the cardiovascular system.
Topics: Aged; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Cardiac Output; Cerebrovascular Disorders; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Regional Blood Flow; Renin; Stroke Volume; Vascular Resistance | 1978 |
Pharmacologic interruption of the renin-angiotensin system.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Kidney; Renin; Structure-Activity Relationship | 1979 |
Arterial wall or plasma renin in hypertension?
Topics: Angiotensin II; Animals; Antibodies; Aorta; Arteries; Blood Pressure; Dogs; Humans; Hypertension; Hypertension, Renovascular; Nephrectomy; Rats; Renin | 1979 |
Physiologic studies with saralasin in animals.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Blood Pressure; Central Nervous System; Dogs; Glomerular Filtration Rate; Hemodynamics; Hypertension; Norepinephrine; Rabbits; Rats; Receptors, Angiotensin; Renin; Saralasin; Sodium | 1979 |
Angiotensin as a renal, adrenal, and cardiovascular hormone: responses to saralasin in normal man and in essential and secondary hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cardiovascular System; Diet; False Positive Reactions; Humans; Hypertension; Hypertension, Renal; Kidney; Posture; Rabbits; Receptors, Angiotensin; Renin; Saralasin; Sodium; Teprotide | 1979 |
[Prostaglandins, kallikrein-kinin and dopamine. Practical implications of this vasodilator-natriuretic system].
Topics: Aldosterone; Angiotensin II; Anti-Inflammatory Agents; Arachidonic Acids; Bartter Syndrome; Bradykinin; Dopamine; Edema; Humans; Hyperaldosteronism; Hypertension; Hypotension, Orthostatic; Kallikreins; Kidney; Kinins; Myocardial Infarction; Natriuresis; Prostaglandins; Receptors, Dopamine; Renin; Thromboxane A2; Vasodilation | 1979 |
[Kidney in chronic arterial hypertension: "resetting" and the role of the renal medulla in its development].
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Chronic Disease; Diuresis; Homeostasis; Humans; Hypertension; Hypertrophy; Kidney; Kidney Medulla; Kidney Tubules; Natriuresis; Nephrosclerosis; Renin; Vascular Resistance | 1979 |
[Angiotensin II analogue and essential hypertension].
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Angiotensin II; Blood Pressure; Child; Female; Humans; Hypertension; Hypertension, Renal; Male | 1979 |
[Renal kallikrein-kinin system and control of blood pressure (author's transl)].
Topics: Angiotensin II; Animals; Blood Pressure; Diuresis; Diuretics; Female; Humans; Hypertension; Kallikreins; Kidney; Kininogens; Kinins; Mineralocorticoids; Natriuresis; Pregnancy; Prostaglandins; Rats; Renin | 1979 |
Salivary kallikrein excretion in hypertension.
Topics: Absorption; Angiotensin II; Animals; Blood Pressure; Catecholamines; Enzyme Activation; Esterases; Humans; Hypertension; Kallikreins; Mineralocorticoids; Parotid Gland; Rats; Renin; Saliva; Salivary Glands; Salivation; Secretory Rate; Sodium | 1979 |
[Renin-angiotensin-aldosterone system: the present status and problems].
Topics: Aldosterone; Angiotensin II; Animals; Enzyme Activation; Enzyme Precursors; Feedback; Humans; Hyperaldosteronism; Hypertension; Nephrectomy; Receptors, Angiotensin; Renin | 1979 |
Prostaglandins in circulatory disorders.
Topics: Angiotensin II; Antihypertensive Agents; Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Platelets; Diet; Dipyridamole; Eicosanoic Acids; Humans; Hypertension; Platelet Aggregation; Prostaglandins; Thrombosis; Thromboxanes; Vascular Diseases | 1979 |
[The saralasin test in clinical evaluation of hypertensive states].
Topics: Adult; Angiotensin II; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renovascular; Male; Middle Aged; Renin; Saralasin | 1978 |
[Clinical application of renin-angiotensin system blockade in hypertension].
Topics: Angiotensin II; Humans; Hypertension; Juxtaglomerular Apparatus; Renin | 1979 |
[Side effects of oral contraceptives].
Topics: Angiotensin II; Contraceptives, Oral; Feedback; Female; Fetus; Hemolytic-Uremic Syndrome; Humans; Hypertension; Liver; Myocardial Infarction; Pregnancy; Vitamin A | 1976 |
Interrelations of renin, angiotensin II, and sodium in hypertension and renal failure.
Topics: Acute Kidney Injury; Aldosterone; Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rate; Homeostasis; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Regional Blood Flow; Renin; Sodium; Water-Electrolyte Balance | 1976 |
Effect of antihypertensive drugs on the renin-angiotensin system.
Topics: Angiotensin II; Antihypertensive Agents; Catecholamines; Contraceptives, Oral; Diuretics; Drug Interactions; Humans; Hypertension; Kidney; Levodopa; Lithium; Receptors, Adrenergic; Renin; Steroids; Sympathetic Nervous System; Time Factors | 1976 |
[Does the renin-angiotensin system participate in the pathogenesis of arterial hypertension in cases of aortic coarctation?].
Topics: Age Factors; Aged; Angiotensin II; Animals; Aortic Coarctation; Dogs; Humans; Hypertension; Kidney; Middle Aged; Renin; Time Factors | 1976 |
[Clinical aspects of hypertension under contraceptive steroids].
Topics: Adult; Aldosterone; Angiotensin II; Black or African American; Black People; Contraceptives, Oral; Europe; Female; Humans; Hypertension; Time Factors; United States; White People | 1976 |
[Angiotensin antagonists in the diagnosis and treatment of renin-dependent hypertension].
Topics: Angiotensin II; Humans; Hypertension; Juxtaglomerular Apparatus; Renin; Saralasin | 1976 |
Angiotensin antagonists as diagnostic and pharmacologic tools.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Kidney; Kinetics; Propranolol; Renal Artery Obstruction; Renal Veins; Renin; Saralasin; Vasodilator Agents; Water-Electrolyte Balance | 1976 |
The renal circulation in hypertensive disease.
Topics: Angiotensin II; Animals; Body Fluids; Disease Models, Animal; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Kidney; Microcirculation; Rats; Regional Blood Flow; Sodium; Vasoconstrictor Agents; Vasodilator Agents | 1976 |
The second Volhard Lecture: The use of blocking agents to define the functions of the renin--angiotensin system.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Calcium; Dogs; Hypertension; Hypertension, Renal; Kidney; Norepinephrine; Propranolol; Rabbits; Rats; Renin; Saralasin; Sodium | 1975 |
Vasopressor substances in normal and abnormal pregnancy.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Arginine Vasopressin; Catecholamines; Female; Humans; Hypertension; Placental Lactogen; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Prolactin; Renin; Vasoconstrictor Agents | 1975 |
Complications of systemic contraceptive agents: hypertension.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Drug Combinations; Estrogens; Female; Hemodynamics; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Progestins; Prospective Studies; Renin | 1975 |
[Effect of vasopressor agents on the vessel wall].
Topics: Angiotensin II; Animals; Blood Pressure; Blood Proteins; Blood Vessels; Carotid Arteries; Cats; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Glucocorticoids; Guinea Pigs; Hindlimb; Hypertension; Hypertension, Renal; Kidney; Mineralocorticoids; Norepinephrine; Prostaglandins; Rabbits; Rats; Regional Blood Flow; Retinal Vessels; Saphenous Vein; Serotonin; Vasoconstrictor Agents; Vasopressins | 1975 |
Aldosterone and renin in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adult; Age Factors; Aldosterone; Angiotensin II; Clinical Trials as Topic; Endopeptidases; Furosemide; Hemodynamics; Humans; Hypertension; Liver Circulation; Metabolic Clearance Rate; Middle Aged; Receptors, Adrenergic; Renin; Secretory Rate; Sodium | 1975 |
Hypertension of chronic renal failure: role of sodium and the renal pressor system.
Topics: Adult; Angiotensin II; Female; Homeostasis; Humans; Hypertension; Hypertension, Malignant; Kidney Failure, Chronic; Nephrectomy; Renal Dialysis; Renin; Sodium; Uremia | 1975 |
[Oral contraceptives and hypertension. A review].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Female; Hemodynamics; Humans; Hypertension; Renin | 1975 |
Inter-relationships between plasma angiotensin II, arterial pressure, aldosterone and exchangeable sodium in normotensive and hypertensive man.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Potassium; Renin; Sodium | 1975 |
The clinical value of renin and angiotensin estimations.
Topics: Acute Kidney Injury; Addison Disease; Angiotensin II; Bartter Syndrome; Contraceptives, Oral; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Hypotension, Orthostatic; Kidney Diseases; Kidney Failure, Chronic; Kidney Neoplasms; Male; Pregnancy; Pregnancy Complications, Cardiovascular; Renal Artery Obstruction; Renin | 1975 |
[Pathophysiology of hypertension].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Hemodynamics; Humans; Hypertension; Hypertension, Malignant; Models, Biological; Renin; Sympathetic Nervous System; Vascular Resistance | 1975 |
Rationale for the chemical development of angiotensin II receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Drug Design; Humans; Hypertension; Imidazoles; Losartan; Renin-Angiotensin System; Tetrazoles | 1992 |
Peptides as targets for antihypertensive drug development.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Endothelins; Humans; Hypertension; Molecular Sequence Data; Neprilysin; Neuropeptide Y; Renin; Renin-Angiotensin System | 1992 |
Mechanisms of cardiac growth. The role of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Cardiomegaly; Humans; Hypertension; Myocardium; Renin-Angiotensin System | 1992 |
Cardioprotection and ACE inhibitors.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Hypertrophy, Left Ventricular; Myocardial Infarction; Prognosis | 1992 |
Diastolic dysfunction in pressure-overload hypertrophy and its modification by angiotensin II: current concepts.
Topics: Angiotensin II; Animals; Cardiomegaly; Diastole; Enzyme Activation; Heart; Humans; Hypertension; Myocardium; Peptidyl-Dipeptidase A | 1992 |
The role of angiotensin II in vascular smooth muscle cell growth.
Topics: Angiotensin II; Animals; Cell Division; Gene Expression; Humans; Hypertension; Models, Biological; Muscle, Smooth, Vascular | 1992 |
Vasoactive peptides and growth factors in the pathophysiology of hypertension.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Cell Differentiation; Cell Division; Cells, Cultured; Endothelins; Extracellular Matrix; Growth Substances; Hypertension; Muscle, Smooth, Vascular; Peptides | 1992 |
Vascular growth in hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Cells, Cultured; Female; Humans; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Rats; Vascular Resistance | 1992 |
The molecular basis of cardiovascular hypertrophy: the role of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Blood Vessels; Cardiomegaly; Cell Division; Cells, Cultured; Gene Expression; Growth Substances; Hypertension; Hypertrophy; Muscle, Smooth, Vascular; Proto-Oncogenes; Renin-Angiotensin System | 1992 |
Role of brain angiotensin in cardiovascular regulation.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Brain Chemistry; Cardiovascular System; Hypertension; Neurotransmitter Agents; Pituitary Hormones; Receptors, Angiotensin; Renin-Angiotensin System | 1992 |
Angiotensin II, vascular structure and blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Cardiomegaly; Growth Substances; Hypertension; Hypertrophy; Models, Cardiovascular; Rats | 1992 |
[Renin-angiotensin system blockade. What can be expected from angiotensin II antagonists?].
Topics: Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Renin-Angiotensin System; Teprotide; Tetrazoles | 1992 |
Brain angiotensin: receptors, actions and possible role in hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Disease Models, Animal; Hypertension; Receptors, Angiotensin | 1992 |
Prevention of structural changes in the heart in hypertension by angiotensin converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Diastole; Heart Failure; Humans; Hypertension; Myocardium; Rats; Rats, Inbred SHR | 1992 |
Blood pressure, angiotensin-converting enzyme (ACE) inhibitors, and the kidney.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hypertension; Hypertension, Renovascular; Kidney; Kidney Failure, Chronic | 1992 |
Angiotensin II, angiotensin-converting enzyme inhibitors, and blood vessel structure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Humans; Hypertension; Rats; Rats, Inbred SHR | 1992 |
[Arterial factors in essential hypertension].
Topics: Angiotensin II; Animals; Humans; Hypertension; Nerve Growth Factors; Norepinephrine; Platelet-Derived Growth Factor; Sympathetic Nervous System; Vascular Resistance | 1992 |
[The characteristics of the regulation of aldosterone secretion (a review of the literature)].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Receptors, Dopamine; Receptors, Serotonin; Renin-Angiotensin System | 1991 |
The renin-angiotensin system: importance in physiology and pathology.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Brain; Humans; Hypertension; Receptors, Angiotensin; Renin-Angiotensin System | 1990 |
Role of contractile agonists in growth regulation of vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Humans; Hypertension; Hypertrophy; Mitogens; Muscle Development; Muscle Proteins; Muscle, Smooth, Vascular; Vasoconstrictor Agents | 1991 |
The greater renin system. Its prorenin-directed vasodilator limb. Relevance to diabetes mellitus, pregnancy, and hypertension.
Topics: Angiotensin II; Diabetes Mellitus; Enzyme Precursors; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy in Diabetics; Renin; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 1991 |
In vivo pharmacology of DuP 753.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Imidazoles; Losartan; Rats; Reference Values; Tetrazoles | 1991 |
Nonparallel effects of renin inhibitor treatment on plasma renin activity and angiotensins I and II in hypertensive subjects. An assay-related artifact.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1991 |
The renin-angiotensin system: renal actions and blood pressure regulation.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Humans; Hypertension; Kidney; Natriuresis; Renin-Angiotensin System | 1991 |
Dysregulation of aldosterone secretion and its relationship to the pathogenesis of essential hypertension.
Topics: Aldosterone; Angiotensin II; Homeostasis; Humans; Hypertension; Renin; Sodium, Dietary | 1991 |
Local hormonal factors (intracrine, autocrine, and paracrine) in hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Hormones; Humans; Hypertension; Kinins; Protease Inhibitors | 1991 |
Control of blood pressure by the renin-angiotensin-aldosterone system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Kidney; Renin-Angiotensin System | 1991 |
Functional derangements in the regulation of aldosterone secretion in hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Kidney; Renin; Sodium; Sodium, Dietary | 1991 |
Nonpeptide angiotensin II receptor antagonists: a novel class of antihypertensive agents.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Biphenyl Compounds; Hypertension; Imidazoles; Receptors, Angiotensin; Vasoconstriction | 1990 |
Neurovascular mechanisms and sodium balance in the pathogenesis of hypertension.
Topics: Angiotensin II; Animals; Blood Vessels; Brain; Central Nervous System; Endothelium, Vascular; Hypertension; Models, Biological; Nervous System Physiological Phenomena; Sodium | 1991 |
Relation between sodium intake, renal function, and the regulation of arterial pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Body Water; Humans; Hypertension; Kidney; Sodium; Sympathetic Nervous System | 1991 |
Anesthetic implications of the renin-angiotensin system and angiotensin-converting enzyme inhibitors.
Topics: Anesthesia; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Intraoperative Period; Renin-Angiotensin System | 1991 |
[Renin-angiotensin-aldosterone system in arterial hypertension].
Topics: Angiotensin II; Humans; Hypertension; Renin-Angiotensin System | 1990 |
Various approaches to blockade of the renin-angiotensin system: persistent renin response.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biological Availability; Humans; Hypertension; Renin; Renin-Angiotensin System | 1990 |
[Pathophysiology of the renin-angiotensin system].
Topics: Acute-Phase Reaction; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Juxtaglomerular Apparatus; Renin; Renin-Angiotensin System | 1990 |
The renin-angiotensin system in hypertension: an update.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Heart Failure; Humans; Hypertension; Renin; Renin-Angiotensin System | 1990 |
In vivo concentrations of kinins and angiotensins.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bridged Bicyclo Compounds; Humans; Hypertension; Kinins; Radioimmunoassay; Ramipril | 1990 |
Dopaminergic regulation of aldosterone secretion. Biochemical mechanisms and pharmacology.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Biomechanical Phenomena; Cyclic AMP; Dihydroergotoxine; Dopamine; Humans; Hypertension; Receptors, Dopamine; Receptors, Dopamine D2 | 1990 |
Importance of the renin-angiotensin-aldosterone system (RAS) in the physiology and pathology of hypertension. An overview.
Topics: Angiotensin II; Animals; Brain; Humans; Hypertension; Renin-Angiotensin System | 1990 |
Diabetes mellitus, the renin-angiotensin system, and angiotensin-converting enzyme inhibition.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Humans; Hypertension; Kidney; Rats; Receptors, Angiotensin; Renin; Sodium | 1990 |
Angiotensin, ACE inhibition, and the renal circulation: pathogenesis of nonmodulation in essential hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hypertension; Kidney; Renal Circulation; Renin; Sodium | 1990 |
Role of angiotensin in the renal vasoconstriction observed during the development of genetic hypertension.
Topics: Angiotensin II; Animals; Glomerular Filtration Rate; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Renin-Angiotensin System; Vasoconstriction | 1990 |
New angiotensin converting enzyme inhibitors. Their role in the management of hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cerebrovascular Disorders; Heart Failure; Humans; Hypertension; Potassium; Renin; Renin-Angiotensin System; Risk Factors | 1990 |
Renal protective effects of angiotensin converting enzyme inhibitors.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Heart Rate; Hemodynamics; Humans; Hypertension; Isoquinolines; Kidney; Kidney Failure, Chronic; Kidney Tubules; Quinapril; Sodium; Tetrahydroisoquinolines | 1990 |
Acute and chronic effects of angiotensin converting enzyme inhibitors on the essential hypertensive kidney.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Kidney; Time Factors | 1990 |
Regulation of large cerebral arteries and cerebral microvascular pressure.
Topics: Angiotensin II; Arterioles; Arteriosclerosis; Blood Pressure; Brain; Cerebral Arteries; Cerebrovascular Circulation; Humans; Hypertension; Ischemic Attack, Transient; Microcirculation; Sympathetic Nervous System; Thromboxanes; Vascular Resistance; Vasopressins | 1990 |
Local modulation of adrenergic neurotransmission in blood vessels.
Topics: Acetylcholine; Acidosis; Adenosine; Angiotensin II; Animals; Blood Vessels; Cardiac Glycosides; Epinephrine; Histamine; Humans; Hypertension; Muscle, Smooth, Vascular; Neurotransmitter Agents; Norepinephrine; Potassium; Receptors, Adrenergic; Serotonin; Sympathetic Nervous System; Temperature | 1985 |
Effects of angiotensin converting enzyme inhibition: a clinical point of view.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Circulation; Blood Pressure; Bradykinin; Brain; Heart Rate; Humans; Hypertension; Renin-Angiotensin System; Sodium | 1985 |
Dopaminergic receptor mechanisms modulating the renin-angiotensin system and aldosterone secretion: an overview.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Dopamine; Dopamine Agents; Humans; Hypertension; Rats; Receptors, Dopamine; Renin; Renin-Angiotensin System; Sodium | 1989 |
[Physiopathology of arterial hypertension. Significance of the renin-angiotensin-aldosterone system and structural changes].
Topics: Angiotensin II; Cardiomegaly; Coronary Disease; Humans; Hypertension; Hypertrophy; Renin-Angiotensin System | 1989 |
Immunologic approaches to blockade of the renin-angiotensin system: a review.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Humans; Hypertension; Immunization, Passive; Immunotherapy; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1989 |
Diabetic nephropathy: hemodynamic basis and implications for disease management.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Fatty Acids, Unsaturated; Hemodynamics; Humans; Hypertension; Kidney Failure, Chronic; Kidney Glomerulus; Proteinuria; Renin-Angiotensin System | 1989 |
Endogenous opiates and the pathogenesis of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Endorphins; Hypertension; Hypertension, Renovascular; Models, Cardiovascular; Naloxone; Narcotics; Pain; Pressoreceptors; Shock | 1989 |
The renin angiotensin system: importance in physiology and pathology.
Topics: Angiotensin II; Animals; Brain; Humans; Hypertension; Renin-Angiotensin System | 1989 |
The renin-angiotensin system. Normal physiology and changes in older hypertensives.
Topics: Aging; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Natriuresis; Renin-Angiotensin System; Water-Electrolyte Imbalance | 1989 |
Sodium-sensitive hypertension. Implications of pathogenesis for therapy.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diet, Sodium-Restricted; Disease Susceptibility; Humans; Hypertension; Kidney; Renal Circulation; Sodium Chloride | 1989 |
Angiotensin-converting enzyme inhibition versus blockade of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Renin; Renin-Angiotensin System | 1989 |
New therapeutic prospects of renin-angiotensin system inhibition.
Topics: Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Heart Failure; Humans; Hypertension; Renin-Angiotensin System | 1989 |
Possible mechanism for the renoprotective effect of angiotensin converting enzyme inhibitors.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hypertension; Kidney Failure, Chronic; Kidney Glomerulus; Rats; Renin-Angiotensin System | 1989 |
Brain angiotensin: pathways and pharmacology.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Brain; Hypertension; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1988 |
Angiotensin-converting enzyme inhibitors. Relationship between pharmacodynamics and pharmacokinetics.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Drug Interactions; Heart Failure; Humans; Hypertension; Kidney Failure, Chronic; Liver Diseases; Metabolic Clearance Rate; Peptidyl-Dipeptidase A | 1988 |
Evolution of angiotensin-converting enzyme inhibitors.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Drug Design; Enalapril; Heart Failure; Humans; Hypertension; Renin-Angiotensin System | 1988 |
[The renin-angiotensin system: systemic and local function].
Topics: Angiotensin II; Cardiomegaly; Coronary Disease; Heart Failure; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1988 |
Angiotensin-converting enzyme inhibitors: past, present, and bright future.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Dipeptides; Drug Eruptions; Drug Interactions; Enalapril; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Diseases; Neutropenia; Proline; Taste Disorders | 1985 |
Antihypertensive therapy: newer concepts and agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Volume; Calcium Channel Blockers; Diuretics; Hemodynamics; Humans; Hypertension; Hypokalemia; Membrane Potentials; Receptors, Serotonin; Renin; Solubility; Vascular Resistance; Vasodilator Agents | 1985 |
[GABA and central regulation of cardiovascular function].
Topics: Angiotensin II; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Baclofen; Benzodiazepines; Bicuculline; Blood Pressure; Brain Mapping; Cardiovascular Physiological Phenomena; Cardiovascular System; Cats; Central Nervous System; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Muscimol; Rabbits; Reflex; Reticular Formation; Synaptic Transmission; Vasomotor System; Vasopressins | 1985 |
The dual role of angiotensin and vasopressin as plasma hormones and neuropeptides in cardiovascular regulation.
Topics: Angiotensin II; Angiotensinogen; Animals; Arginine Vasopressin; Blood Pressure; Brain; Brain Mapping; Cardiovascular Physiological Phenomena; Cardiovascular System; Cattle; Desoxycorticosterone; Dogs; Humans; Hypertension; Hypothalamo-Hypophyseal System; Mice; Neurotransmitter Agents; Oxytocin; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride; Subfornical Organ | 1985 |
Renin secretion responsiveness: understanding the efficacy of renin-angiotensin inhibition.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Humans; Hypertension; Posture; Renin; Renin-Angiotensin System; Sodium; Water-Electrolyte Balance | 1988 |
Atrial natriuretic peptide: a new factor in hormonal control of blood pressure and electrolyte homeostasis.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Circulation; Blood Pressure; Diet, Sodium-Restricted; Dogs; Hemodynamics; Homeostasis; Humans; Hypertension; Kidney; Muscle, Smooth, Vascular; Potassium; Rabbits; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride | 1986 |
The endocrine control of blood volume, blood pressure and sodium balance: atrial hormone and renin system interactions.
Topics: Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Volume; Calcium; Humans; Hypertension; Muscle, Smooth, Vascular; Natriuresis; Renin-Angiotensin System; Sodium; Vasoconstriction; Water-Electrolyte Balance | 1986 |
Pharmacological influences on aldosterone secretion.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Dopamine; Histamine; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Pituitary Hormones; Potassium; Renin; Serotonin | 1987 |
The renin-angiotensin system and body function.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Brain; Hemorrhage; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Pituitary Gland; Renin; Renin-Angiotensin System; Water-Electrolyte Balance | 1985 |
[Some advances in angiotensin converting enzyme inhibitors].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Heart Failure; Humans; Hypertension; Oligopeptides; Prostaglandins; Scleroderma, Systemic; Structure-Activity Relationship; Teprotide | 1985 |
Significance of the vascular renin-angiotensin pathway.
Topics: Angiotensin II; Animals; Blood Vessels; Captopril; Enalapril; Humans; Hypertension; Hypertension, Renovascular; Receptors, Adrenergic, beta; Renin; Renin-Angiotensin System; Vascular Resistance | 1986 |
[Angiotensin converting enzyme: its levels and its effect on blood pressure regulation].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Bradykinin; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1986 |
Aldosterone, calcium, and hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Humans; Hypertension; In Vitro Techniques; Metoclopramide; Renin | 1986 |
Relation of renin-angiotensin system activity to left ventricular hypertrophy and function in experimental and human hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Humans; Hypertension; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 1987 |
Effects of angiotensin II and of angiotensin converting enzyme inhibition in chronic renal failure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Hemodynamics; Humans; Hypertension; Kidney Failure, Chronic; Kidney Glomerulus; Renin-Angiotensin System | 1987 |
[The renin-angiotensin system in hypertension and heart insufficiency: current aspects in the use of ACE inhibitors].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Cushing Syndrome; Humans; Hypertension; Hypertension, Renovascular; Renin-Angiotensin System | 1988 |
Comparison of the effects of calcium antagonists and converting enzyme inhibitors on renal function under normal and hypertensive conditions.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Humans; Hypertension; Kidney; Kidney Tubules; Urodynamics | 1988 |
Emerging issues in the cellular biology of the cardiovascular system.
Topics: Angiotensin II; Animals; Cardiovascular System; Cells, Cultured; Hemodynamics; Hormones; Humans; Hypertension; Platelet-Derived Growth Factor; Renin-Angiotensin System | 1988 |
Clinical applications of antimineralocorticoids.
Topics: Aldosterone; Angiotensin II; Ascites; Glucose; Heart Failure; Humans; Hypertension; Liver Cirrhosis; Mineralocorticoids; Renin; Water-Electrolyte Balance | 1988 |
Prostaglandins, renin-angiotensin system, and hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Pressure; Dinoprostone; Female; Humans; Hypertension; Indomethacin; Pregnancy; Prostaglandins; Prostaglandins E; Renin; Renin-Angiotensin System; Vasoconstriction | 1985 |
Large conduit arteries in hypertension: role of the vascular renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Arteriosclerosis; Hemodynamics; Humans; Hypertension; Renin-Angiotensin System | 1988 |
Prostanoids as mediators of prohypertensive and antihypertensive mechanisms.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Prostaglandins; Sodium, Dietary; Thromboxanes | 1988 |
Hemodynamic and neurohormonal changes in the development of DOC hypertension in the dog.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Dogs; Hemodynamics; Hypertension; Pressoreceptors; Renin; Sodium; Vasopressins | 1988 |
Renin and reproduction.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Extraembryonic Membranes; Female; Genitalia, Female; Humans; Hypertension; Menstrual Cycle; Ovary; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins; Rabbits; Renin; Reproduction; Research | 1988 |
Angiotensin and the renal circulation in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hypertension; Renal Circulation; Renin-Angiotensin System | 1988 |
Mechanisms underlying pressure-related natriuresis: the role of the renin-angiotensin and prostaglandin systems. State of the art lecture.
Topics: Angiotensin II; Blood Pressure; Calcium; Epoprostenol; Glomerular Filtration Rate; Hypertension; Kidney; Muscle, Smooth, Vascular; Natriuresis; Prostaglandins; Renal Circulation; Renin-Angiotensin System; Sodium | 1988 |
The role of the renin-angiotensin system in hypertension.
Topics: Angiotensin II; Animals; Dogs; Hemangiopericytoma; Humans; Hypertension; Rats; Renal Artery Obstruction; Renin; Renin-Angiotensin System | 1988 |
[Pharmacological and immunological approaches to inhibiting the renin-angiotensin system].
Topics: Angiotensin II; Animals; Antibodies; Antibodies, Monoclonal; Antihypertensive Agents; Depression, Chemical; Heart Failure; Humans; Hypertension; Immunization, Passive; Immunotherapy; Renin; Renin-Angiotensin System | 1987 |
The renin-angiotensin system in the central control of blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Humans; Hypertension; Renin-Angiotensin System | 1987 |
Hypertension and the kidney: lessons learned from transplantation.
Topics: Angiotensin II; Animals; Disease Models, Animal; Graft Occlusion, Vascular; Graft Rejection; Humans; Hypertension; Hypertension, Renovascular; Kidney; Kidney Transplantation; Postoperative Complications; Rats; Steroids | 1987 |
[Changes in the regulation mechanisms of plasma angiotensin II production in arterial hypertension].
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Renin | 1987 |
Pathogenesis of diabetic microangiopathy. The hemodynamic view.
Topics: Angiotensin II; Animals; Basement Membrane; Blood Pressure; Capillaries; Capillary Permeability; Catecholamines; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Hemodynamics; Humans; Hypertension; Hypoxia; Kidney Glomerulus; Microcirculation; Prostaglandins; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Retinal Vessels; Vasodilation | 1986 |
[Current status and prospects of the laboratory diagnosis of arterial hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Catecholamines; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Kinins; Natriuretic Agents; Pheochromocytoma; Potassium; Prostaglandins; Renin; Serotonin; Vasopressins | 1986 |
The renin-angiotensin system and long-term regulation of arterial pressure.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Fluids; Feedback; Hypertension; Kidney; Natriuresis; Renin-Angiotensin System; Sympathetic Nervous System | 1986 |
Regulation of arterial pressure: role of pressure natriuresis and diuresis.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Diuresis; Homeostasis; Humans; Hypertension; Kidney; Natriuresis; Renin-Angiotensin System; Vasopressins | 1986 |
Control of vascular reactivity in pregnancy.
Topics: Angiotensin II; Blood Pressure; Blood Vessels; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Renin-Angiotensin System | 1987 |
Disorders of mineralocorticoid activity.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Specimen Collection; Brain Neoplasms; Circadian Rhythm; Dexamethasone; Diagnosis, Differential; Evoked Potentials; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Intestinal Mucosa; Mineralocorticoids; Models, Biological; Posture; Radionuclide Imaging; Renin; Spironolactone; Tomography, X-Ray Computed; Ultrasonography | 1985 |
The site of angiotensin production.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Humans; Hypertension; Renin-Angiotensin System; Sheep | 1985 |
[Angiotensin antagonists].
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renovascular; Saralasin; Structure-Activity Relationship | 1985 |
The renin-angiotensin system in the control of systemic arterial pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System; Sodium; Sympathetic Nervous System; Time Factors; Vasoconstriction | 1985 |
[Genes of blood pressure regulatory factors].
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cloning, Molecular; DNA; Genes; Humans; Hypertension; Kallikreins; Kininogens; Kinins; Renin; Renin-Angiotensin System; RNA, Messenger | 1985 |
The renal pressor system in human pregnancy.
Topics: Aldosterone; Alpha-Globulins; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Pre-Eclampsia; Pregnancy; Renin; Uterus | 1972 |
[Current problems in active substance research. 4. Central effects of angiotensin II].
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cats; Central Nervous System; Dogs; Drug Antagonism; Drug Interactions; Drug Synergism; Heart Rate; Hypertension; Mammals; Norepinephrine; Oligopeptides; Pressoreceptors; Rabbits; Rats; Stimulation, Chemical; Synaptic Transmission; Urethane; Vasoconstrictor Agents | 1974 |
[Hemodynamic and hormonologic basis of the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Cardiac Output; Catecholamines; Diuretics; Drug Synergism; Heart Rate; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Pheochromocytoma; Renin; Sympatholytics; Vasodilator Agents | 1974 |
["Hypertensive vascular changes" with and without hypertension].
Topics: Angiotensin II; Blood Vessels; Chronic Disease; Diarrhea; Female; Humans; Hyalin; Hyperaldosteronism; Hyperplasia; Hypertension; Hypertension, Malignant; Hypertrophy; Male; Necrosis; Nephrotic Syndrome; Renin; Vomiting | 1969 |
The renin-angiotensin system and its relation to hypertension.
Topics: Angiotensin II; Blood; Humans; Hypertension; In Vitro Techniques; Renin | 1965 |
Aldosteronism and hypertension.
Topics: Aldosterone; Angiotensin II; Hyperaldosteronism; Hypertension; Renin | 1965 |
[Biochemistry of renin-angiotensin--with special reference to angiotensinase].
Topics: Angiotensin II; Animals; Cats; Endopeptidases; Humans; Hypertension; Liver Diseases; Renin | 1967 |
[Activity of renin-angiotensin in normal and abnormal conditions].
Topics: Adrenal Gland Diseases; Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Kidney Diseases; Renin | 1967 |
[Studies on te effects of renin on the development of hypertension].
Topics: Adrenal Cortex Hormones; Angiotensin II; Animals; Hypertension; Lysosomes; Renin | 1967 |
[The importance of angiotensin in clinical practice].
Topics: Aldosterone; Anaphylaxis; Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rate; Humans; Hypertension; Mitral Valve Stenosis; Shock, Septic; Shock, Surgical | 1966 |
Pathophysiology of hypertension.
Topics: Aldosterone; Angiotensin II; Aorta; Carotid Sinus; Humans; Hypertension; Hypothalamus; Juxtaglomerular Apparatus; Kidney; Pressoreceptors; Renin; Sympathetic Nervous System; Vasopressins; Water-Electrolyte Balance | 1967 |
Vascular reactivity in human hypertension.
Topics: Angiotensin II; Catecholamines; Humans; Hypertension; Hypertension, Renal; Vascular Resistance; Vasoconstrictor Agents | 1968 |
Vascular reactivity in experimental hypertension.
Topics: Angiotensin II; Animals; Hypertension; Norepinephrine; Rats; Vascular Resistance; Vasoconstrictor Agents | 1968 |
Tissue hormones: angiotensin, bradykinin and the regulation of regional blood flows.
Topics: Aldosterone; Angiotensin II; Animals; Autonomic Nervous System; Bradykinin; Calcium; Catecholamines; Dogs; Female; Glomerular Filtration Rate; Humans; Hypertension; Ischemia; Kallikreins; Kidney; Liver Cirrhosis; Neurosecretion; Regional Blood Flow; Renin; Sodium Chloride; Uterus | 1968 |
[Recent concept of primary aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Insufficiency; Aldosterone; Angiotensin II; Carbohydrate Metabolism; Electrophoresis; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay; Renin | 1967 |
[The renin-angiotensin-aldosterone system in late gestosis].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Pre-Eclampsia; Pregnancy; Renin | 1968 |
[Sodium in experimental hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Desoxycorticosterone; Extracellular Space; Hypertension; Hypertension, Renal; Male; Nephrectomy; Potassium; Rats; Renin; Sodium; Water-Electrolyte Balance | 1965 |
[Symposium on problems of essential arterial hypertension. Etiopathogenesis of essential hypertension].
Topics: Age Factors; Angiotensin II; Arteries; Constriction; Diet; Endocrine Glands; Habits; Humans; Hypertension; Nervous System; Obesity; Racial Groups; Renin; Sex Factors | 1968 |
[Hypokalemic hypertension].
Topics: Acid-Base Equilibrium; Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Angiotensin II; Diuretics; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypertension, Renal; Hypokalemia; Kidney Tubules; Mineralocorticoids; Potassium; Pyelonephritis; Renin; Water-Electrolyte Balance | 1968 |
Recent developments in pathophysiologic studies of the renin-angiotensin system.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Amino Acid Sequence; Angiotensin II; Biological Assay; Diagnosis, Differential; Feedback; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Kidney Function Tests; Protein Binding; Radioimmunoassay; Renal Artery Obstruction; Renin | 1969 |
Neurogenic control of the blood pressure in hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Central Nervous System; Humans; Hypertension; Kidney; Pressoreceptors; Renin; Water-Electrolyte Balance | 1967 |
Control of aldosterone secretion by the renin-angiotensin system and by corticotropin.
Topics: Addison Disease; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Hypopituitarism; Hypotension; In Vitro Techniques; Kidney Diseases; Pheochromocytoma; Pituitary Gland; Pituitary Hormones, Anterior; Potassium; Pregnancy; Renin; Serotonin; Sodium; Stress, Physiological; Stress, Psychological; Sympathetic Nervous System | 1968 |
[Renin--facts and hypotheses].
Topics: Acid-Base Equilibrium; Aldosterone; Amino Acids; Angiotensin II; Animals; Fibrinolysis; Humans; Hypertension; Kinins; Renin | 1968 |
[Experimental bases of the pathophysiology of the renin-angiotensin system].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Female; Humans; Hyperaldosteronism; Hypertension; Kidney; Male; Pre-Eclampsia; Pregnancy; Rats; Renin | 1968 |
[Renin-angiotensin-aldosterone system in blood pressure regulation disorders].
Topics: Adult; Aldosterone; Angiotensin II; Child; Electrolytes; Female; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hyperplasia; Hypertension; Juxtaglomerular Apparatus; Kidney; Male; Middle Aged; Pituitary-Adrenal System; Renal Artery Obstruction; Renin | 1968 |
[Significance of renin in physiopathology and diagnosis].
Topics: Acute Kidney Injury; Aldosterone; Angiography; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Kidney; Kidney Function Tests; Kidney Glomerulus; Renal Artery Obstruction; Renin | 1969 |
[Early diagnosis and treatment of hypertension and renal vascular hypertension].
Topics: Adolescent; Adult; Age Factors; Angiotensin II; Cardiomyopathies; Cerebrovascular Disorders; Diagnosis, Differential; Female; Heart Failure; Humans; Hypertension; Hypertension, Renal; Kidney Function Tests; Male; Middle Aged; Radioisotope Renography; Renin | 1969 |
[The role of renin in the pathophysiology and diagnosis, excluding pregnancy and its complications].
Topics: Aldosterone; Angiotensin II; Extracellular Space; Humans; Hyperaldosteronism; Hypertension; Kidney; Renin | 1969 |
[Changes in renal hemodynamics and function in cardiac insufficiency].
Topics: Aldosterone; Angiotensin II; Animals; Arteriovenous Anastomosis; Cardiac Volume; Catecholamines; Diuretics; Heart Failure; Hemodynamics; Hypertension; Kidney; Kidney Tubules; Oxygen; Sodium; Vascular Resistance; Vasomotor System; Vasopressins; Veins; Water-Electrolyte Balance | 1969 |
[Hyperaldosteronism and the renin-angiotensin system].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Animals; Catecholamines; Cushing Syndrome; Diagnosis, Differential; Dogs; Feedback; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Mixed Function Oxygenases; Renin; Time Factors | 1969 |
[Pharmacodynamic aspects of associations of hypertension with other medicinal factors].
Topics: Acetazolamide; Angiotensin II; Animals; Atropine; Chlorpromazine; Dogs; Humans; Hypertension; Monoamine Oxidase Inhibitors; Rabbits; Rats | 1969 |
[Diagnosis of renovascular hypertension by means of differential renal function studies].
Topics: Angiography; Angiotensin II; Diuresis; Humans; Hypertension; Hypertension, Renal; Kidney Function Tests; Radioisotope Renography; Renal Artery Obstruction | 1969 |
[Pathogenesis of arterial hypertension. Current trends and prospectives].
Topics: Aldosterone; Angiotensin II; Animals; Blood Vessels; Cardiac Output; Catecholamines; Humans; Hypertension; Prostaglandins; Renin; Sympathetic Nervous System | 1969 |
[Angiotensinases].
Topics: Aminopeptidases; Angiotensin II; Carboxypeptidases; Endopeptidases; Female; Humans; Hypertension; Liver Diseases; Methods; Pre-Eclampsia; Pregnancy; Protease Inhibitors; Renin | 1969 |
[The renin--angiotensin--aldosterone system].
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Blood Volume; Child; Corticosterone; Dogs; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney; Kidney Diseases; Rats; Renin; Sheep; Sodium; Stimulation, Chemical; Tissue Extracts; Water-Electrolyte Balance | 1969 |
[Maintenance of blood pressure, with special reference to renin-angiotensin system].
Topics: Angiotensin II; Animals; Blood Pressure; Endopeptidases; Humans; Hypertension; Renin | 1969 |
[Renin-angiotensin-aldosterone system from the pathophysiological viewpoint].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Cats; Chemical Phenomena; Chemistry; Diuresis; Diuretics; Dogs; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Methods; Natriuresis; Rabbits; Rats; Regional Blood Flow; Renin; Sympathetic Nervous System | 1969 |
[Endocrine function tests for etiological diagnosis of hypertensive patients].
Topics: Adult; Aldosterone; Angiotensin II; Catecholamines; Cushing Syndrome; Endocrine Glands; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Male; Pheochromocytoma; Renin | 1970 |
[Aetiology and pathogenesis of chronic arterial hypertension].
Topics: Angiotensin II; Animals; Arteries; Blood Circulation; Blood Viscosity; Body Weight; Catecholamines; Cushing Syndrome; Diet; Hemodynamics; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Mineralocorticoids; Psychophysiologic Disorders; Renal Artery Obstruction; Renin; Sodium | 1970 |
The renin-angiotensin system in clinical medicine.
Topics: Angiotensin II; Animals; Blood Pressure; Endocrine System Diseases; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Hypotension; Kidney; Kidney Diseases; Kidney Tubules; Pregnancy; Renin; Sodium; Sympathetic Nervous System | 1970 |
[Role of the adrenal cortex in the pathogenesis of hypertension].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Hydrocortisone; Hyperaldosteronism; Hypertension; Renin | 1970 |
[Role of prostaglandins in the pathogenesis of arterial hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Muscle, Smooth; Prostaglandins; Renin | 1970 |
[Hypertension caused by oral contraceptives].
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Renin | 1971 |
[Juxtaglomerular cell tumor and aldosterone-secreting renal tumor].
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Female; Hemangiopericytoma; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Juxtaglomerular Apparatus; Kidney Neoplasms; Male; Microscopy, Electron; Polyuria; Renin | 1971 |
[Hypertensions caused by hypermineralocorticism].
Topics: Adrenocortical Hyperfunction; Adult; Alkalosis; Angiotensin II; Diagnosis, Differential; Female; Glycyrrhiza; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middle Aged; Mineralocorticoids; Plants, Medicinal; Potassium; Renin; Sodium | 1971 |
Hypertension and chronic renal failure.
Topics: Aldosterone; Angiotensin II; Body Weight; Humans; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Myocardium; Nephrectomy; Renal Dialysis; Renin; Sodium | 1971 |
The relationship between angiotensin and aldosterone.
Topics: Adrenal Gland Neoplasms; Aldosterone; Alkalosis; Angiotensin II; Animals; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Metabolism, Inborn Errors; Mixed Function Oxygenases; Renin; Sodium | 1971 |
Perspectives in aldosterone and renin control.
Topics: Aldosterone; Angiotensin II; Animals; Bionics; Glomerular Filtration Rate; Humans; Hyperaldosteronism; Hypertension; Natriuresis; Renin; Sheep; Sodium | 1971 |
[On mechanisms acting upon arterial blood pressure and sodium metabolism, particularly during pregnancy].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Feedback; Female; Humans; Hypertension; Kidney; Kidney Glomerulus; Nephrectomy; Pregnancy; Progesterone; Rats; Regional Blood Flow; Renin; Sodium; Vagotomy; Water-Electrolyte Balance | 1971 |
[The renin-angiotensin-aldosterone system in arterial hypertension].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Diagnosis, Differential; Feedback; Glomerular Filtration Rate; Homeostasis; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Kidney; Kidney Glomerulus; Nephrectomy; Renin | 1971 |
[Pathogenesis of essential hypertension with special reference to therapy].
Topics: Adolescent; Adrenal Glands; Adult; Aged; Angiotensin II; Blood Pressure; Blood Volume; Diazepam; Diuretics; Female; Guanethidine; Hexamethonium Compounds; Humans; Hypertension; Hypertension, Renal; Male; Mecamylamine; Methyldopa; Middle Aged; Phytotherapy; Plants, Medicinal; Psychophysiologic Disorders; Rauwolfia; Sleep; Time Factors; Vascular Resistance | 1971 |
[The renin-angiotensin-aldosterone system in arterial hypertension].
Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Glomerular Filtration Rate; Homeostasis; Humans; Hypertension; Kidney; Kidney Neoplasms; Kidney Transplantation; Muscle Contraction; Muscles; Renin; Sodium | 1971 |
[Arterial hypertension and oral contraceptives].
Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Body Weight; Contraceptives, Oral; Diuretics; Ethinyl Estradiol; Female; Hemodynamics; Humans; Hypertension; Mestranol; Parity; Prediabetic State; Renin | 1971 |
[The renin-angiotensin system in patients with cirrhosis of the liver].
Topics: Angiotensin II; Ascites; Chronic Disease; Endopeptidases; Hepatitis A; Humans; Hypertension; Liver Cirrhosis; Renin | 1971 |
Circulation: overall regulation.
Topics: Aldosterone; Angiotensin II; Blood Circulation; Blood Pressure; Body Fluids; Cardiac Output; Heart Failure; Homeostasis; Hypertension; Hypertension, Renal; Kidney; Models, Biological; Natriuresis; Nephrosis; Oxygen; Physical Exertion; Pressoreceptors; Reflex; Renin; Systems Analysis | 1972 |
[Angiotensin I-converting enzyme activity; determination methods and current topics].
Topics: Angiotensin II; Animals; Carbon Tetrachloride Poisoning; Endopeptidases; Humans; Hydrogen-Ion Concentration; Hypertension; Hypertension, Renal; Lung; Perfusion; Protease Inhibitors; Rabbits; Rats; Renin | 1971 |
[Significance of plasma renin substrate determination].
Topics: Angiotensin II; Animals; Contraceptives, Oral; Dogs; Humans; Hypertension; Rabbits; Rats; Renin; Stimulation, Chemical | 1971 |
Hormonal steroid contraceptives. IV. Adverse reactions and management of the patient.
Topics: Angiotensin II; Blood Glucose; Blood Pressure; Blood Proteins; Body Weight; Breast Neoplasms; Carbohydrates; Cholestasis; Contraceptives, Oral; Female; Gingiva; Humans; Hypertension; Jaundice; Lipids; Liver; Renin; Skin; Uterine Cervical Neoplasms; Uterine Neoplasms | 1971 |
A viewpoint concerning the enigma of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arteries; Cardiac Output; Dogs; Electrolytes; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney; Prostaglandins; Rats; Renal Artery; Renin; Sympathetic Nervous System; Vascular Resistance; Water | 1972 |
Physiologic characteristics of hypertension.
Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Volume; Cardiac Output; Catecholamines; Extracellular Space; Female; Hemodynamics; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Male; Pheochromocytoma; Plasma Volume; Stress, Physiological; Vascular Resistance; Vasomotor System | 1972 |
Renin, angiotensin and aldosterone system in pathogenesis and management of hypertensive vascular disease.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aldosterone; Angiotensin II; Contraceptives, Oral; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Hypokalemia; Kidney; Kidney Diseases; Potassium; Renin; Sodium | 1972 |
[Experimental neurogenic hypertension].
Topics: Angiotensin II; Animals; Aorta; Autonomic Nervous System; Blood Pressure; Brachiocephalic Trunk; Carotid Arteries; Catecholamines; Cats; Cerebral Ventricles; Disease Models, Animal; Dogs; Haplorhini; Hemodynamics; Hot Temperature; Hypertension; Kaolin; Methods; Rabbits; Rats; Subclavian Artery; Sympathectomy; Vascular Diseases | 1972 |
[Control systems of arterial pressure].
Topics: Angiotensin II; Animals; Blood Pressure; Blood Volume; Cardiac Output; Cats; Central Nervous System; Cerebrovascular Circulation; Chemoreceptor Cells; Dogs; Heart; Heart Failure; Humans; Hypertension; Hypotension; Ischemic Attack, Transient; Kidney; Posture; Pressoreceptors; Reflex; Renin; Vascular Resistance; Venous Pressure | 1972 |
[The contraceptive pill and blood pressure].
Topics: Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Time Factors | 1972 |
The cardiovascular effects of oral contraceptives.
Topics: Aldosterone; Angiotensin II; Blood Coagulation; Blood Flow Velocity; Blood Vessels; Cardiovascular System; Cerebrovascular Disorders; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Migraine Disorders; Muscle, Smooth; Myocardial Infarction; Platelet Adhesiveness; Pregnancy; Pulmonary Embolism; Renin; Thromboembolism; Thrombosis; Varicose Veins; Veins | 1972 |
Salt, water, and rest as a preventative for toxemia of pregnancy. A commentary and review.
Topics: Aldosterone; Angiotensin II; Blood Volume; Body Weight; Diabetes Insipidus; Diuresis; Diuretics; Edema; Female; Humans; Hypertension; Kidney; Posture; Pre-Eclampsia; Pregnancy; Renin; Rest; Sodium Chloride; Urinary Tract Infections; Water | 1972 |
Radioimmunoassay of angiotensin and determination of renin activity.
Topics: Angiotensin II; Diuretics; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Iodine Isotopes; Isotope Labeling; Menstruation; Posture; Radioimmunoassay; Renin | 1972 |
[Abnormalities of sodium and water metabolism with special reference to hypertensive diseases].
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney Failure, Chronic; Liver Cirrhosis; Natriuresis; Renin; Sodium; Water; Water-Electrolyte Balance | 1972 |
18-Hydroxy-11-deoxycorticosterone (18-OH-DOC) secretion in experimental and human hypertension.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Angiotensin II; Animals; Cushing Syndrome; Dexamethasone; Diet; Dogs; Female; Humans; Hydroxycorticosteroids; Hyperaldosteronism; Hypertension; Isotope Labeling; Ketosteroids; Male; Methods; Pregnanes; Rats; Sodium; Steroid Hydroxylases; Tritium | 1972 |
Endocrine causes of hypertension.
Topics: Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aldosterone; Angiotensin II; Catecholamines; Diagnosis, Differential; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney; Pheochromocytoma; Pituitary-Adrenal Function Tests; Renin | 1973 |
The role of renal factors in the pathogenesis of experimental hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cadmium; Cattle; Chronic Disease; Embolism; Glomerulonephritis; Hypertension; Hypertension, Renal; Infarction; Ischemia; Kidney; Kidney Transplantation; Nephrectomy; Prostaglandins; Pyelonephritis; Renal Artery; Renin; Sodium Chloride; Transplantation, Homologous | 1973 |
The physiology of renin.
Topics: Aldosterone; Angiotensin II; Edema; Extracellular Space; Female; Glomerular Filtration Rate; Humans; Hyperaldosteronism; Hypertension; Hypotension; Juxtaglomerular Apparatus; Kidney; Kidney Diseases; Kidney Failure, Chronic; Natriuresis; Potassium; Pregnancy; Pregnancy Complications; Pressoreceptors; Regional Blood Flow; Renal Artery Obstruction; Renin; Vasopressins | 1973 |
A model of the human circulation. Regulation by autonomic nervous system and renin-angiotensin system, and influence of blood volume on cardiac output and blood pressure.
Topics: Angiotensin II; Autonomic Nervous System; Blood Circulation; Blood Flow Velocity; Blood Pressure; Blood Volume; Cardiac Output; Coronary Circulation; Extracellular Space; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Metabolic Clearance Rate; Models, Biological; Pressoreceptors; Pulmonary Circulation; Renin; Sodium; Vascular Resistance | 1973 |
Clinical significance of hemodynamic findings in hypertension.
Topics: Angiotensin II; Blood Pressure; Blood Viscosity; Blood Volume; Cardiac Output; Cardiomegaly; Diuretics; Heart Rate; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Propranolol; Receptors, Adrenergic; Renin | 1973 |
Renomedullary interstitial cells (RIC), prostaglandins (PG) and the antihypertensive function of the kidney.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Cells, Cultured; Chromatography, Thin Layer; Culture Techniques; Depression, Chemical; Hypertension; Kidney; Kidney Medulla; Lipids; Lipoproteins; Microscopy, Electron; Plethysmography; Prostaglandins; Rabbits; Transplantation, Homologous | 1973 |
[Some new aspects of the renin-angiotensin system].
Topics: Aldosterone; Angiotensin II; Animals; Brain Chemistry; Dogs; Female; Humans; Hypertension; Mineralocorticoids; Nephrectomy; Rats; Renin | 1973 |
Renin, angiotensin and hypertensive vascular damage: a review.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Capillary Permeability; Dilatation; Hypertension; Ischemia; Macromolecular Substances; Rats; Renal Artery Obstruction; Renin; Vascular Diseases | 1973 |
Aldosterone: review of its physiology and diagnostic aspects of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Desoxycorticosterone; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Hypokalemia; Potassium; Radiography; Renin; Sodium; Spironolactone | 1973 |
The pathophysiology of renin.
Topics: Aldosterone; Angiotensin II; Animals; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Kidney; Kidney Diseases; Kidney Tubules, Distal; Nephrectomy; Nephrosclerosis; Pressoreceptors; Renin; Sympathetic Nervous System | 1973 |
Arterial hypertension in retrospect.
Topics: Adrenal Glands; Angiotensin II; Arteriosclerosis; Blood Flow Velocity; Blood Pressure; Cardiac Output; Humans; Hypertension; Models, Biological; Muscle, Smooth; Nervous System; Plasma Volume; Prostaglandins; Renal Artery; Vascular Resistance; Water-Electrolyte Balance | 1974 |
Sound deprivation causes hypertension in rats.
Topics: Adrenalectomy; Angiotensin II; Animals; Blood Pressure; Body Weight; Catecholamines; Desoxycorticosterone; Female; Growth Hormone; Hippocampus; Hypertension; Hypophysectomy; Methylprednisolone; Norepinephrine; Rats; Reticular Formation; Sensory Deprivation; Sound; Tyramine; Vasopressins | 1973 |
[Review of research on essential hypertension].
Topics: Angiotensin II; Blood Pressure; Central Nervous System; Humans; Hypertension; Kidney; Norepinephrine; Pressoreceptors; Prostaglandins; Renin; Sodium; Sympathetic Nervous System; Vasomotor System | 1973 |
[Na metabolism anomaly in essential hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Natriuresis; Plasma Volume; Renin; Sodium | 1973 |
[Present status of research on hypertension-inducing substances].
Topics: Angiotensin II; Catecholamines; Humans; Hypertension; Hypertension, Renal; Renin | 1973 |
[Sensitizing factor and natriuretic hormones as hypertension-inducing factors].
Topics: Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Natriuresis; Norepinephrine; Renin; Sodium | 1973 |
[Renin-angiotensin-aldosterone system in essential hypertension].
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin; Spironolactone | 1973 |
[Renin-angiotensin-(aldosterone)-system-clinical aspects].
Topics: Acute Kidney Injury; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Desoxycorticosterone; Glycyrrhiza; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Hypertension, Renal; Kidney Neoplasms; Pheochromocytoma; Plants, Medicinal; Renin | 1973 |
Perspectives on the renin-angiotensin-aldosterone system in hypertension.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Male; Metabolic Clearance Rate; Methods; Mineralocorticoids; Renin | 1974 |
Editorial: The kidney and uric acid excretion in man.
Topics: Angiotensin II; Animals; Biological Transport, Active; Blood Proteins; Diabetes Insipidus; Diet, Sodium-Restricted; Diuretics; Dogs; Extracellular Space; Gout; Haplorhini; Humans; Hypertension; Kidney; Kidney Tubules, Proximal; Nephrons; Norepinephrine; Protein Binding; Pyrazinamide; Sodium; Uric Acid | 1972 |
The role of the renal medulla in hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cardiac Output; Desoxycorticosterone; Extracellular Space; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney; Kidney Medulla; Kidney Transplantation; Lipids; Plasma Volume; Pressoreceptors; Prostaglandins; Renin; Sodium; Transplantation, Homologous | 1974 |
Diabetes and hypertensive vascular disease. Mechanisms and treatment.
Topics: Alloxan; Angiotensin II; Animals; Blood Volume; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Humans; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Nephrosclerosis; Rats; Renin; Sympathetic Nervous System | 1973 |
[Primary hypo- and hyperreninism].
Topics: Addison Disease; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Volume; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hyperkalemia; Hypernatremia; Hypertension; Hypertension, Renal; Hypokalemia; Juxtaglomerular Apparatus; Kidney Neoplasms; Magnesium; Male; Mineralocorticoids; Pheochromocytoma; Renin | 1974 |
Catecholamine metabolism in health and disease.
Topics: Angiotensin II; Bacteria; Brain; Catecholamines; Diet; Dopamine; Dysautonomia, Familial; Humans; Hypertension; Hypopituitarism; Intestines; Neurons; Norepinephrine; Parkinson Disease; Phenylketonurias; Renin; Stomach; Sympathetic Nervous System | 1974 |
The renin-angiotensin system (first of two parts).
Topics: Aldosterone; Angiotensin II; Animals; Autonomic Nervous System; Biological Assay; Blood Pressure; Chemical Phenomena; Chemistry; Humans; Hypertension; Kidney; Radioimmunoassay; Receptors, Adrenergic; Renin | 1974 |
[Primary aldosteronism].
Topics: Aldosterone; Angiotensin II; Desoxycorticosterone; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin | 1973 |
[Review on internal medicine, 1973--nephrology. 5. The renin-angiotensin system (author's transl)].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cerebrovascular Disorders; Chronic Disease; Glomerulonephritis; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Propranolol; Renin | 1974 |
Laboratory test results altered by "The Pill".
Topics: Adrenal Glands; Angiotensin II; Blood Coagulation; Blood Coagulation Tests; Carbohydrate Metabolism; Clinical Laboratory Techniques; Contraceptives, Oral; Depression, Chemical; Estrogens; Gonadotropin-Releasing Hormone; Hematopoiesis; Humans; Hypertension; Hypothalamus; Jaundice; Lipid Metabolism; Liver; Liver Function Tests; Male; Nandrolone; Pituitary Gland; Proteins; Renin; Stimulation, Chemical; Thyroid Function Tests; Thyroid Gland | 1974 |
[Renin and sodium and the formation of vascular lesions in hypertension].
Topics: Angiotensin II; Animals; Body Water; Capillary Permeability; Desoxycorticosterone; Dogs; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Mineralocorticoids; Nephrectomy; Rats; Renal Artery Obstruction; Renin; Sodium; Vascular Diseases; Vascular Resistance; Vasoconstrictor Agents | 1974 |
[Renin-angiotensin system in hypertension].
Topics: Angiotensin II; Animals; Diagnosis, Differential; Dogs; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Juxtaglomerular Apparatus; Rabbits; Rats; Renin | 1974 |
Low-renin hypertension.
Topics: Adrenal Glands; Age Factors; Aldosterone; Angiotensin II; Blood Volume; Extracellular Space; Female; Humans; Hyperaldosteronism; Hypertension; Kidney; Male; Mineralocorticoids; Potassium; Renin; Sex Factors; Vascular Resistance | 1974 |
[Oral contraceptives and arterial hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Blood Circulation; Blood Pressure; Body Weight; Contraceptives, Oral; Female; Heart Rate; Humans; Hyperaldosteronism; Hypertension; Pregnancy; Rats; Renin; Time Factors | 1974 |
[Changes in the hemodynamics of patients with hypertension].
Topics: Aldosterone; Angiotensin II; Blood Flow Velocity; Blood Pressure; Cardiac Output; Heart; Hemodynamics; Humans; Hypertension; Kidney; Pulmonary Circulation; Pulse; Receptors, Adrenergic; Renin; Vascular Resistance | 1974 |
[The renin-angiotensin system and its role in the regulation of arterial pressure and renal function].
Topics: Angiotensin II; Animals; Blood Pressure; Cattle; Dogs; Humans; Hypertension; Kidney; Kidney Tubules; Mice; Rabbits; Rats; Renin; Swine | 1974 |
Hypertension in pregnancy.
Topics: Angiotensin II; Antihypertensive Agents; Female; Hemodynamics; Humans; Hypertension; Kidney Glomerulus; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Vascular Resistance; Water-Electrolyte Imbalance | 1974 |
297 trial(s) available for angiotensin ii and Hypertension
| Article | Year |
|---|---|
Aerobic exercise improves central blood pressure and blood pressure variability among patients with resistant hypertension: results of the EnRicH trial.
Topics: Angiotensin II; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Exercise; Humans; Hypertension; Interferon-gamma; Nitric Oxide; Prospective Studies; Pulse Wave Analysis; Superoxide Dismutase; Vascular Stiffness | 2023 |
Effect of angiotensin II receptor blocker and salt supplementation on short-term blood pressure variability in type 2 diabetes.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Humans; Hypertension; Renin; Renin-Angiotensin System; Sodium Chloride; Sodium Chloride, Dietary | 2020 |
Association of Angiotensin II-Stimulating Antihypertensive Use and Dementia Risk: Post Hoc Analysis of the PreDIVA Trial.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Dementia; Female; Humans; Hypertension; Incidence; Male; Sodium Chloride Symporter Inhibitors | 2021 |
Systemic and tissue-specific effects of aliskiren on the RAAS and carbohydrate/lipid metabolism in obese patients with hypertension.
Topics: Adipose Tissue; Adult; Amides; Amlodipine; Angiotensin II; Antihypertensive Agents; Blood Glucose; Double-Blind Method; Female; Fumarates; Glucose; Humans; Hypertension; Insulin; Lipolysis; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Obesity; Renin; Renin-Angiotensin System | 2017 |
Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Cross-Over Studies; Diet, Sodium-Restricted; Humans; Hypertension; Middle Aged; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sodium Chloride, Dietary; Vasoconstrictor Agents; Young Adult | 2018 |
Thymosin β4 Deficiency Exacerbates Renal and Cardiac Injury in Angiotensin-II-Induced Hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Hypertension; Infusions, Intravenous; Male; Mice; Mice, Knockout; Microfilament Proteins; Random Allocation; Rats; Thymosin | 2018 |
Lowering Effects of n-3 Fatty Acid Supplements on Blood Pressure by Reducing Plasma Angiotensin II in Inner Mongolia Hypertensive Patients: A Double-Blind Randomized Controlled Trial.
Topics: Adult; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; China; Dietary Supplements; Double-Blind Method; Fatty Acids, Omega-3; Female; Fish Oils; Humans; Hypertension; Linseed Oil; Male; Middle Aged | 2019 |
A randomized controlled trial comparing methohexital and propofol for induction in patients receiving angiotensin axis blockade.
Topics: Aged; Anesthesia; Anesthetics, Intravenous; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arginine Vasopressin; Epinephrine; Feasibility Studies; Female; Humans; Hypertension; Hypotension; Male; Methohexital; Middle Aged; Norepinephrine; Propofol | 2019 |
Effect of acute and chronic vitamin D administration on systemic renin angiotensin system in essential hypertensives and controls.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcitriol; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Receptors, Calcitriol; Renin; Renin-Angiotensin System; Vitamin D | 2013 |
Polymorphisms of the angiotensin II type 1 receptor gene affect antihypertensive response to angiotensin receptor blockers in hypertensive Chinese.
Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Asian People; Benzimidazoles; Benzoates; Blood Pressure; Drug Administration Schedule; Essential Hypertension; Female; Genotype; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Single-Blind Method; Telmisartan; Young Adult | 2013 |
Angiotensin-(1-7)-induced renal vasodilation in hypertensive humans is attenuated by low sodium intake and angiotensin II co-infusion.
Topics: Angiotensin I; Angiotensin II; Diet, Sodium-Restricted; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Peptide Fragments; Renal Circulation; Renin-Angiotensin System; Sodium, Dietary; Vasodilation | 2013 |
Long-term antihypertensive effects of aliskiren, a direct renin inhibitor, in chronic hemodialysis patients.
Topics: Aged; Amides; Angiotensin II; Antihypertensive Agents; Blood Pressure; Female; Fumarates; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Renin; Renin-Angiotensin System; Time Factors; Treatment Outcome | 2013 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Relationship, Drug; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Parathyroid Glands; Parathyroid Hormone; Renin-Angiotensin System; Spironolactone; Vasoconstrictor Agents; Vitamin D | 2014 |
Effect of imidapril versus ramipril on urinary albumin excretion in hypertensive patients with type 2 diabetes and microalbuminuria.
Topics: Adult; Aged; Albumins; Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Imidazolidines; Male; Middle Aged; Natriuretic Peptide, Brain; Prospective Studies; Ramipril; Treatment Outcome | 2013 |
[Hemodynamic variations during tracheal intubation with intubating laryngeal mask airway versus direct laryngoscope in hypertensive patients].
Topics: Aged; Angiotensin II; Female; Hemodynamics; Humans; Hypertension; Intubation, Intratracheal; Laryngeal Masks; Laryngoscopy; Male; Middle Aged | 2013 |
[Effect of loop diuretics with different elimination half-lives on natriuresis changes and indicators characterizing the state of renal tubulointerstitial tissue].
Topics: Adult; Angiotensin II; Chronic Disease; Delayed-Action Preparations; Female; Half-Life; Heart Failure; Humans; Hypertension; Kidney Tubules; Male; Middle Aged; Natriuresis; Sodium Potassium Chloride Symporter Inhibitors; Sulfonamides; Torsemide | 2014 |
Inappropriately elevated endothelin-1 plays a role in the pathogenesis of intradialytic hypertension.
Topics: Adrenomedullin; Adult; Aged; Aldosterone; Angiotensin II; Endothelin-1; Female; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Nitric Oxide; Norepinephrine; Peptidyl-Dipeptidase A; Renal Dialysis | 2015 |
Low Response of Renin-Angiotensin System to Sodium Intake Intervention in Chinese Hypertensive Patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure Determination; China; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Treatment Outcome | 2016 |
Changeover Trial of Azilsartan and Olmesartan Comparing Effects on the Renin-Angiotensin-Aldosterone System in Patients with Essential Hypertension after Cardiac Surgery (CHAOS Study).
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Blood Pressure; Cardiac Surgical Procedures; Drug Substitution; Essential Hypertension; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Oxadiazoles; Prospective Studies; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome; Ventricular Remodeling | 2016 |
Development of hypertension and effects of benazepril hydrochloride in a canine remnant kidney model of chronic renal failure.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Dog Diseases; Dogs; Female; Hypertension; Kidney Failure, Chronic; Male; Renin | 2008 |
Exaggerated hypertensive response to exercise in patients with diastolic heart failure.
Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Exercise; Exercise Test; Female; Heart Failure, Diastolic; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Quality of Life; Tetrazoles; Treatment Outcome | 2008 |
Comparison of the long-term effects of candesartan and olmesartan on plasma angiotensin II and left ventricular mass index in patients with hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Male; Middle Aged; Natriuretic Peptide, Brain; Peptidyl-Dipeptidase A; Tetrazoles | 2010 |
Effects of the angiotensin II receptor blocker losartan on the monocyte expression of biglycan in hypertensive patients.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biglycan; Blood Pressure; C-Reactive Protein; Female; Humans; Hypertension; Interleukin-6; Losartan; Male; Middle Aged; Monocytes; Receptors, Angiotensin; RNA, Messenger; Tumor Necrosis Factor-alpha | 2010 |
A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin I; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 2010 |
Effects of ACE inhibitors on cardiac angiotensin II and aldosterone in humans: "Relevance of lipophilicity and affinity for ACE".
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Aorta, Thoracic; Cardiac Catheterization; Coronary Sinus; Female; Humans; Hydrophobic and Hydrophilic Interactions; Hypertension; Lipids; Lisinopril; Male; Middle Aged; Perindopril; Prospective Studies; Pulmonary Wedge Pressure; Quinapril; Renin-Angiotensin System; Tetrahydroisoquinolines; Young Adult | 2010 |
Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels.
Topics: Aged; Angiotensin II; Animals; Blood Pressure; Bradykinin; Carcinoma, Renal Cell; Cells, Cultured; Coronary Circulation; Endothelial Cells; Endothelin-1; Female; Gastrointestinal Stromal Tumors; Heart; Heart Rate; Humans; Hypertension; In Vitro Techniques; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Rats; Rats, Inbred WKY; Receptor Protein-Tyrosine Kinases; Renin; Sunitinib; Vascular Endothelial Growth Factor A | 2010 |
Fibrinolysis and insulin sensitivity in imidapril and candesartan (FISIC study) recipients with hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelium, Vascular; Female; Fibrinolysis; Humans; Hypertension; Imidazolidines; Insulin Resistance; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Prospective Studies; Signal Transduction; Single-Blind Method; Tetrazoles; Tissue Plasminogen Activator; Treatment Outcome; Young Adult | 2011 |
Tagging SNPs in REN, AGTR1 and AGTR2 genes and response of renin activity, angiotensin II and aldosterone concentrations to antihypertensive treatment in Kazakans.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; China; Double-Blind Method; Ethnicity; Female; Genetic Association Studies; Humans; Hypertension; Male; Middle Aged; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin | 2011 |
Role of angiotensin II in plasma PAI-1 changes induced by imidapril or candesartan in hypertensive patients with metabolic syndrome.
Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Mass Index; Cholesterol; Cholesterol, HDL; Female; Humans; Hypertension; Imidazolidines; Insulin; Male; Metabolic Syndrome; Middle Aged; Plasminogen Activator Inhibitor 1; Tetrazoles; Triglycerides; Young Adult | 2011 |
Effects of olmesartan on the renin-angiotensin-aldosterone system for patients with essential hypertension after cardiac surgery--investigation using a candesartan change-over study.
Topics: Aged; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Benzimidazoles; Biphenyl Compounds; Cardiac Surgical Procedures; Compliance; Drug Substitution; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Japan; Male; Middle Aged; Prospective Studies; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome | 2011 |
Abnormal increase in urinary aquaporin-2 excretion in response to hypertonic saline in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Aquaporin 2; Atrial Natriuretic Factor; Cross-Over Studies; Cyclic AMP; Dinoprostone; Epithelial Sodium Channels; Female; Glomerular Filtration Rate; Humans; Hypertension; Linear Models; Male; Middle Aged; Natriuretic Peptide, Brain; Osmolar Concentration; Renin; Sodium; Sodium, Dietary; Vasopressins | 2012 |
Vitamin D3 therapy corrects the tissue sensitivity to angiotensin ii akin to the action of a converting enzyme inhibitor in obese hypertensives: an interventional study.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cholecalciferol; Drug Resistance; Drug Synergism; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Renal Plasma Flow; Vitamin D Deficiency | 2012 |
Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial.
Topics: Aged; Aldosterone; Amiloride; Angiotensin II; Aquaporin 2; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Epithelial Sodium Channels; Female; Furosemide; Humans; Hypertension; Kidney Tubules; Male; Middle Aged; Potassium; Pulse Wave Analysis; Renin; Sodium; Spironolactone | 2013 |
Angiotensin II, independent of plasma renin activity, contributes to the hypertension of autonomic failure.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Captopril; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Orthostatic Intolerance; Pure Autonomic Failure; Renin; Sodium | 2013 |
[Effect of irbesartan, an antagonist of AT-1 receptors for angiotensin II, on L-arginine metabolism in arterial hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arginase; Arginine; Biphenyl Compounds; Blood Donors; Blood Pressure; Erythrocytes; Humans; Hypertension; Irbesartan; Nitric Oxide Synthase; Receptors, Angiotensin; Tetrazoles | 2002 |
Effects of enalapril and losartan on circulating adhesion molecules and monocyte chemotactic protein-1.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cell Adhesion Molecules; Chemokine CCL2; Double-Blind Method; E-Selectin; Enalapril; Enzyme Inhibitors; Female; Humans; Hypertension; Intercellular Adhesion Molecule-1; Losartan; Male; Middle Aged; Prospective Studies; Vascular Cell Adhesion Molecule-1 | 2002 |
Augmentation of myocardial blood flow in hypertensive heart disease by angiotensin antagonists: a comparison of lisinopril and losartan.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Coronary Circulation; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Losartan; Male; Middle Aged; Tomography, Emission-Computed | 2002 |
Prevention of cardiovascular morbidity with angiotension receptor blockade: life after LIFE.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Atenolol; Clinical Protocols; Diabetes Complications; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Morbidity; Risk | 2002 |
Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Circulation; Renin; Tetrazoles; Valine; Valsartan | 2002 |
Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease.
Topics: Adolescent; Adult; Aged; Angioplasty; Angiotensin II; Antioxidants; Biomarkers; Blood Glucose; Cholesterol; Cross-Sectional Studies; Dinoprost; F2-Isoprostanes; Female; Homocysteine; Humans; Hypertension; Hypertension, Renovascular; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Platelet Activation; Reference Values; Renal Artery Obstruction; Renin; Renin-Angiotensin System; Thromboxane B2; Triglycerides; Vitamins | 2002 |
Vasoconstricting effect of angiotensin II in human hand veins: influence of aging, diabetes mellitus and hypertension.
Topics: Adult; Aged; Aging; Angiotensin II; Diabetes Mellitus, Type 2; Hand; Humans; Hypertension; Male; Middle Aged; Tachyphylaxis; Vasoconstriction; Vasoconstrictor Agents; Veins | 2002 |
Effect of angiotensin ii receptor blockade on arterial stiffness: beyond blood pressure reduction.
Topics: Aged; Angiotensin II; Antihypertensive Agents; Aorta; Blood Pressure; Brachial Artery; Cross-Over Studies; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Vascular Resistance | 2002 |
[Metabolic effects of angiotensin-II receptor blockers].
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cholesterol; Endothelium, Vascular; Fibrin; Humans; Hypertension; Imidazoles; Male; Receptors, Angiotensin; Thiophenes | 2002 |
[Angiotensin II receptor blocker telmisartan: effect on 24-hour blood pressure profile and left ventricular hypertrophy in patients with hypertension].
Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Circadian Rhythm; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Receptors, Angiotensin; Telmisartan | 2002 |
Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes.
Topics: Amputation, Surgical; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Combined Modality Therapy; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Exercise; Female; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Male; Middle Aged; Myocardial Infarction; Obesity; Risk Factors; Smoking Cessation; Stroke; Vitamins | 2003 |
Role of angiotensin II in L-NAME-induced systemic and renal hemodynamic effects in hydrochlorothiazide-pretreated hypertensive subjects.
Topics: Angiotensin II; Antihypertensive Agents; Diuresis; Diuretics; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Glomerular Filtration Rate; Hemodynamics; Hormones; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Natriuresis; NG-Nitroarginine Methyl Ester; Renal Circulation; Sodium Chloride Symporter Inhibitors | 2003 |
[Change of natural antibody levels in patients with cardiovascular diseases by the use of anti-atherogenic diets with processed soy product foods].
Topics: Adult; Aged; alpha-Macroglobulins; Angiotensin II; Antibodies; Antithrombin III; Cardiovascular Diseases; Cholesterol; Diet Therapy; Dietary Proteins; Female; Food Handling; Humans; Hypertension; Male; Middle Aged; Myocardial Ischemia; Soybean Oil; Soybean Proteins; Thrombin; Triglycerides | 2002 |
Effects of angiotensin II receptor antagonism on the renal hemodynamic response to cardiovascular stress.
Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endocrine Glands; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Imidazoles; Lower Body Negative Pressure; Male; Renal Circulation; Severity of Illness Index; Thiophenes | 2003 |
Cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial of patients with type 2 diabetes and overt nephropathy.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Irbesartan; Kidney Failure, Chronic; Male; Middle Aged; Placebos; Risk Factors; Tetrazoles; Treatment Outcome | 2003 |
Effects of valsartan with or without benazepril on blood pressure, angiotensin II, and endoxin in patients with essential hypertension.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Cardenolides; Digoxin; Female; Humans; Hypertension; Male; Middle Aged; Saponins; Tetrazoles; Valine; Valsartan | 2003 |
[The Steno-2 study. Intensive multifactorial intervention reduces the occurrence of cardiovascular disease in patients with type 2 diabetes].
Topics: Amputation, Surgical; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Combined Modality Therapy; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Exercise; Female; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Hypolipidemic Agents; Male; Middle Aged; Myocardial Infarction; Obesity; Risk Factors; Smoking Cessation; Stroke; Vitamins | 2003 |
Interactions of L-arginine, isosorbide mononitrate, and angiotensin II inhibitors on arterial pulse wave.
Topics: Aged; Aged, 80 and over; Angiotensin II; Arginine; Arteries; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Diastole; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Isosorbide Dinitrate; Male; Middle Aged; Nitric Oxide Donors; Posture; Pulse; Systole; Time Factors; Treatment Outcome; Vasoconstrictor Agents | 2003 |
Better renoprotective effect of angiotensin II antagonist compared to dihydropyridine calcium channel blocker in childhood.
Topics: Adolescent; Albuminuria; Amlodipine; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Child; Creatinine; Cytoprotection; Female; Humans; Hypertension; Irbesartan; Kidney; Male; Serum Albumin; Tetrazoles | 2003 |
Acute angiotensin II increases plasma F2-isoprostanes in salt-replete human hypertensives.
Topics: Adult; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Drug Interactions; F2-Isoprostanes; Female; Humans; Hypertension; Male; Oxidative Stress; Sodium Chloride | 2003 |
Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angiotensin II; Blood Chemical Analysis; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Endothelin-1; Female; Flavonoids; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitric Oxide; Pinus; Plant Extracts; Platelet Aggregation Inhibitors; Treatment Outcome | 2004 |
Effect of the angiotensin II antagonist valsartan on sexual function in hypertensive men.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Antihypertensive Agents; Blood Pressure; Erectile Dysfunction; Humans; Hypertension; Male; Middle Aged; Orgasm; Patient Satisfaction; Penile Erection; Sexual Behavior; Surveys and Questionnaires; Tetrazoles; Valine; Valsartan | 2003 |
Safety of telmisartan in patients with arterial hypertension : an open-label observational study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Female; Humans; Hypertension; Male; Middle Aged; Product Surveillance, Postmarketing; Risk Factors; Telmisartan | 2004 |
Effects of low-dose nifedipine GITS on sympathetic activity in young and older patients with hypertension.
Topics: Adult; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Middle Aged; Nifedipine; Norepinephrine; Renin; Sympathetic Nervous System | 2004 |
Genetic factors associated with volume-sensitive hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Blood Volume; Calmodulin-Binding Proteins; Diet, Sodium-Restricted; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Phenotype; Predictive Value of Tests; Renin; Renin-Angiotensin System; Sex Factors; Vasoconstrictor Agents | 2004 |
Simvastatin reduces interleukin-1beta secretion by peripheral blood mononuclear cells in patients with essential hypertension.
Topics: Aged; Angiotensin II; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Inflammation; Interleukin-1; Leukocytes, Mononuclear; Lipids; Male; Middle Aged; Simvastatin; Tetrazoles; Valine; Valsartan | 2004 |
Challenges in improving prognosis and therapy: the Ongoing Telmisartan Alone and in Combination with Ramipril Global End point Trial programme.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Germany; Heart Diseases; Humans; Hypertension; Prognosis; Ramipril; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Reduction Behavior; Telmisartan; Treatment Outcome | 2004 |
Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Brachial Artery; Double-Blind Method; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Tetrazoles; Vasodilation | 2004 |
[Clinical study on effect of luohuo capsule in treating essential hypertension of phlegm-stasis blocking collateral type].
Topics: Aged; Angiotensin II; Antihypertensive Agents; Blood Viscosity; Capsules; Diagnosis, Differential; Drugs, Chinese Herbal; Endothelin-1; Female; Hemorheology; Humans; Hypertension; Male; Medicine, Chinese Traditional; Middle Aged; Nitric Oxide; Phytotherapy | 2004 |
Disparate systemic and renal blocking properties of angiotensin II antagonists during exogenous angiotensin II administration: implications for treatment.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Child; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Kidney; Losartan; Middle Aged; Renal Circulation; Renin; Tetrazoles | 2004 |
Losartan increases bradykinin levels in hypertensive humans.
Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Bradykinin; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxylation; Hypertension; Imidazoles; Kallidin; Losartan; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Thiophenes | 2005 |
[Clinical study on effect of qingxin capsule in treating patients with hypertension of mild or moderate degree].
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Antihypertensive Agents; Calcitonin Gene-Related Peptide; Capsules; Double-Blind Method; Drugs, Chinese Herbal; Endothelins; Female; Humans; Hypertension; Male; Middle Aged; Phytotherapy; Quality of Life | 2005 |
Effects of cerivastatin on forearm vascular responses, blood pressure responsiveness and ambulatory blood pressure in type 2 diabetic men.
Topics: Acetylcholine; Aged; Analysis of Variance; Angiotensin II; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Endothelium, Vascular; Forearm; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Infusions, Intravenous; Male; Middle Aged; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Pyridines; Vascular Resistance; Vasodilator Agents | 2005 |
Effects of dual blockade of the renin angiotensin system in hypertensive type 2 diabetic patients with nephropathy.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Biphenyl Compounds; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Perindopril; Renin; Renin-Angiotensin System; Tetrazoles; Treatment Outcome | 2005 |
Sustained 24-hour blockade of the renin-angiotensin system: a high dose of a long-acting blocker is as effective as a lower dose combined with an angiotensin-converting enzyme inhibitor.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypertension; Imidazoles; Lisinopril; Male; Olmesartan Medoxomil; Renin; Renin-Angiotensin System; Tetrazoles | 2005 |
Dual blockade of angiotensin II with enalapril and losartan reduces proteinuria in hypertensive patients with type 2 diabetes.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; C-Reactive Protein; Cystatin C; Cystatins; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Proteinuria; Transforming Growth Factor beta | 2006 |
Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Female; Heart Ventricles; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Spironolactone; Tetrazoles; Ventricular Remodeling | 2006 |
A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibody Specificity; Antihypertensive Agents; Autoantibodies; Blood Pressure; Disease Models, Animal; Double-Blind Method; Drug Evaluation, Preclinical; Humans; Hypertension; Male; Mice; Mice, Inbred BALB C; Middle Aged; Patient Compliance; Ramipril; Rats; Rats, Inbred SHR; Reference Values; Time Factors; Vaccines; Virion | 2007 |
Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Atenolol; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan; Vascular Resistance; Vasodilation | 2007 |
Bovine casein hydrolysate (c12 Peptide) reduces blood pressure in prehypertensive subjects.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Caseins; Cattle; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged | 2007 |
Albuminuria is a target for renoprotective therapy independent from blood pressure in patients with type 2 diabetic nephropathy: post hoc analysis from the Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan (RENAAL) trial.
Topics: Aged; Albuminuria; Angiotensin II; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Placebos | 2007 |
Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Hypertension; Kinetics; Lisinopril; Male; Middle Aged | 2007 |
A comparison of the efficacy and safety of irbesartan/HCTZ combination therapy with irbesartan and HCTZ monotherapy in the treatment of moderate hypertension.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2008 |
Does blockade of the renin angiotensin system affect sympathetic and blood pressure responses to amlodipine in young hypertensive patients?
Topics: Adult; Amlodipine; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Muscle, Skeletal; Norepinephrine; Quinapril; Renin; Sympathetic Nervous System; Tetrahydroisoquinolines | 2007 |
Vaccination against high blood pressure: a new strategy.
Topics: Angiotensin II; Double-Blind Method; Humans; Hypertension; Renin-Angiotensin System; Vaccination; Vasoconstrictor Agents | 2008 |
Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study.
Topics: Adult; Aged; Angiotensin II; Antibody Formation; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Middle Aged; Monitoring, Ambulatory; Oligopeptides; Vaccines, Synthetic | 2008 |
Spironolactone for poorly controlled hypertension in type 2 diabetes: conflicting effects on blood pressure, endothelial function, glycaemic control and hormonal profiles.
Topics: Aged; Aldosterone; Angiotensin II; Blood Glucose; Blood Pressure; Body Mass Index; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Endothelium, Vascular; Female; Fibroblast Growth Factors; Glycated Hemoglobin; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain | 2008 |
Transforming growth factor-beta1 is associated with kidney damage in patients with essential hypertension: renoprotective effect of ACE inhibitor and/or angiotensin II receptor blocker.
Topics: Administration, Inhalation; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Double-Blind Method; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Prospective Studies; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2008 |
Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Clinical Trials as Topic; Diet, Sodium-Restricted; Dipeptides; Double-Blind Method; Enalapril; Enalaprilat; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Random Allocation; Renin; Sodium | 1984 |
Effects of tibalosine, a new alpha-adrenoceptor antagonist, in essential hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin I; Angiotensin II; Blood Glucose; Blood Pressure Determination; Clinical Trials as Topic; Creatinine; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Male; Metabolic Clearance Rate; Middle Aged; Posture; Propanolamines; Renin; Sodium | 1983 |
Blood-pressure response to moderate sodium restriction and to potassium supplementation in mild essential hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Diastole; Diet, Sodium-Restricted; Evaluation Studies as Topic; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Potassium; Random Allocation; Renin; Renin-Angiotensin System; Systole | 1984 |
Monotherapy of hypertension with angiotensin-converting enzyme inhibitors.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Clinical Trials as Topic; Dipeptides; Enalapril; Heart Failure; Humans; Hypertension; Proline; Racial Groups; Teprotide; Time Factors | 1984 |
[A new principle in long-term treatment of essential hypertension: angiotensin-converting enzyme inhibition (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Double-Blind Method; Female; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Posture; Proline; Renin | 1980 |
Fluctuations in the plasma angiotensin I converting enzyme activity during long-term treatment with captopril.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Proline; Renin | 1982 |
Correlation between angiotensin converting enzyme inhibition and the acute hypotensive response to MK 421 in essential hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Dipeptides; Enalapril; Humans; Hypertension; Pulse; Renin | 1982 |
The renin-angiotensin system during converting enzyme inhibition with captopril in patients with severe treatment-resistant hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Blood Pressure; Captopril; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propranolol; Renin; Renin-Angiotensin System | 1984 |
Antihypertensive mechanism of diuretic treatment with chlorthalidone. Complementary roles of sympathetic axis and sodium.
Topics: Adult; Angiotensin II; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Pressoreceptors; Renin; Sodium | 1983 |
Captopril, aldosterone and urinary kallikrein in primary hypertension.
Topics: Aldosterone; Angiotensin II; Captopril; Humans; Hydrochlorothiazide; Hypertension; Kallikreins; Proline; Renin-Angiotensin System | 1983 |
Reduced pressor effect of angiotensin II and of noradrenaline in normal man following the oral administration of the calcium-antagonist nifedipine.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Male; Nifedipine; Norepinephrine; Pulse; Pyridines; Renin | 1982 |
Acute effects of calcitonin gene related peptide on renal haemodynamics and renin and angiotensin II secretion in patients with renal disease.
Topics: Adult; Aged; Angiotensin II; Calcitonin Gene-Related Peptide; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Renal Circulation; Renal Insufficiency; Renin; Time Factors | 1995 |
Renin-angiotensin-aldosterone system, RR interval, and blood pressure variability during postural changes in borderline arterial hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Renin-Angiotensin System | 1995 |
Effects of losartan on the renin-angiotensin-aldosterone axis in essential hypertension.
Topics: Aldosterone; Angiotensin II; Biphenyl Compounds; Blood Pressure; Creatinine; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Renin; Renin-Angiotensin System; Tetrazoles | 1995 |
Angiotensin II-induced hypertension chemotherapy (IHC) for advanced gastrointestinal, pancreatic and hepatobiliary carcinoma.
Topics: Angiotensin II; Biliary Tract Neoplasms; Gastrointestinal Neoplasms; Humans; Hypertension; Liver Neoplasms; Pancreatic Neoplasms | 1995 |
Effects of losartan on a background of hydrochlorothiazide in patients with hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Diastole; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Posture; Potassium; Systole; Tetrazoles; Time Factors; Uric Acid | 1995 |
Effects of angiotensin receptor antagonist and angiotensin converting enzyme inhibitor on insulin sensitivity in fructose-fed hypertensive rats and essential hypertensives.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Diet; Fructose; Glucose Clamp Technique; Humans; Hypertension; Indans; Insulin Resistance; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Tetrazoles | 1995 |
Modulation of the renin-angiotensin-aldosterone system and cough.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cough; Drug Evaluation; Female; Humans; Hypertension; Male; Renin-Angiotensin System | 1995 |
Pharmacodynamic activity of intravenous E-3174, an angiotensin II antagonist, in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Imidazoles; Injections, Intravenous; Kidney Function Tests; Losartan; Male; Middle Aged; Renin; Tetrazoles; Uric Acid | 1994 |
Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Female; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Neurotransmitter Agents; Nifedipine; Norepinephrine; Renin; Tetrazoles | 1994 |
The effect of dietary salt on insulin sensitivity.
Topics: Adult; Angiotensin II; Blood Glucose; Diet, Sodium-Restricted; Glucose Clamp Technique; Hemodynamics; Humans; Hypertension; Insulin; Insulin Resistance; Male; Potassium; Renin; Sodium Chloride, Dietary | 1995 |
Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Asthenia; Atenolol; Biphenyl Compounds; Cough; Dizziness; Double-Blind Method; Fatigue; Felodipine; Female; Headache; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Placebos; Respiratory Tract Infections; Safety; Tetrazoles | 1995 |
Fatty acids enhance vascular alpha-adrenergic sensitivity.
Topics: Adrenergic alpha-Agonists; Adult; Angiotensin II; Black People; Blood Vessels; Dose-Response Relationship, Drug; Drug Combinations; Fat Emulsions, Intravenous; Fatty Acids; Female; Heparin; Humans; Hypertension; Male; Phenylephrine; Vasoconstriction | 1995 |
A randomized, placebo-controlled, double-blind, parallel study of various doses of losartan potassium compared with enalapril maleate in patients with essential hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Tetrazoles | 1995 |
Hemodynamic and biochemical effects of the AT1 receptor antagonist irbesartan in hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Body Weight; Catecholamines; Double-Blind Method; Electrolytes; Female; Hemodynamics; Humans; Hypertension; Irbesartan; Male; Middle Aged; Renin; Tetrazoles | 1995 |
Biochemical effects of losartan, a nonpeptide angiotensin II receptor antagonist, on the renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Norepinephrine; Renin; Renin-Angiotensin System; Tetrazoles | 1995 |
Angiotensin converting enzyme inhibition does not affect response to exogenous angiotensin II in the forearm of mild-moderate hypertensive patients.
Topics: Administration, Oral; Adult; Angiotensin II; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Receptors, Angiotensin; Vasoconstriction | 1994 |
Differences in hormonal and renal vascular responses between normotensive patients with autosomal dominant polycystic kidney disease and unaffected family members.
Topics: Adolescent; Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Models, Biological; Polycystic Kidney, Autosomal Dominant; Renal Circulation; Renal Plasma Flow, Effective; Renin-Angiotensin System; Sodium, Dietary; Vascular Resistance | 1994 |
Effects of pravastatin on cardiovascular reactivity to norepinephrine and angiotensin II in patients with hypercholesterolemia and systemic hypertension.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Cardiovascular System; Cholesterol; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Norepinephrine; Pravastatin; Treatment Outcome | 1995 |
Role of the renin-angiotensin system in hypertension in the elderly.
Topics: Adult; Aged; Aging; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Enalapril; Humans; Hypertension; Middle Aged; Prodrugs; Renin; Renin-Angiotensin System; Tetrazoles | 1994 |
Hemodynamic and neurohumoral effects of fish oil in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Monitors; Female; Fish Oils; Hemodynamics; Humans; Hypertension; Lipids; Male; Middle Aged; Neurotransmitter Agents; Norepinephrine; Renin | 1993 |
Association between cough and angiotensin converting enzyme inhibitors versus angiotensin II antagonists: the design of a prospective, controlled study.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Cough; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Lisinopril; Losartan; Male; Prospective Studies; Research Design; Surveys and Questionnaires; Tetrazoles | 1994 |
Urinary angiotensin II: a marker of renal tissue activity?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Diuretics; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Tritium | 1994 |
Pressure-dependent, enhanced natriuretic response to low-dose, atrial natriuretic peptide infusion in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Case-Control Studies; Female; Humans; Hypertension; Infusions, Intravenous; Kidney; Kidney Function Tests; Male; Middle Aged; Natriuresis; Nitroprusside | 1994 |
Prevention of pregnancy-induced hypertension by calcium supplementation in angiotensin II-sensitive patients.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Calcium; Double-Blind Method; Female; Humans; Hypertension; Incidence; Parity; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors | 1994 |
24-hour ambulatory blood pressure monitoring and spirapril in mild to severe essential hypertension: a randomized dose comparison.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Peptidyl-Dipeptidase A; Renin | 1994 |
Blood pressure effects of acute intravenous renin or oral angiotensin converting enzyme inhibition in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Female; Hemodynamics; Humans; Hypertension; Imidazoles; Injections, Intravenous; Male; Middle Aged; Renin; Time Factors | 1994 |
Effect of temocapril on haemodynamic and humoral responses to exercise in patients with mild essential hypertension.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Exercise; Exercise Test; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Rest; Thiazepines | 1994 |
Differential effects of ACE inhibitors and vasodilators on renal function curve in patients with primary hypertension.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Dihydralazine; Female; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Prospective Studies; Renin; Single-Blind Method; Sodium, Dietary; Vasodilator Agents | 1993 |
A comparison of spirapril and isradipine in patients with diabetic nephropathy and hypertension.
Topics: Adult; Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Double-Blind Method; Enalapril; Endothelium, Vascular; Female; Humans; Hypertension; Isradipine; Lipoproteins; Male; Middle Aged; Potassium; Sodium | 1993 |
Is the antiproteinuric effect of ACE inhibition mediated by interference in the renin-angiotensin system?
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Enalapril; Female; Humans; Hypertension; Imidazoles; Kidney; Losartan; Male; Middle Aged; Proteinuria; Renal Circulation; Renin-Angiotensin System; Tetrazoles | 1994 |
Comparison of blood pressure and angiotensin responses to the renin inhibitor Ro 42-5892 and the angiotensin converting enzyme inhibitor enalapril in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Enalapril; Female; Hemodynamics; Humans; Hypertension; Imidazoles; Male; Middle Aged; Renin | 1993 |
Responses to converting enzyme and renin inhibition. Role of angiotensin II in humans.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Dipeptides; Humans; Hypertension; Male; Middle Aged; Renal Circulation; Renin | 1994 |
Plasma brain natriuretic peptide and endopeptidase 24.11 inhibition in hypertension.
Topics: Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Double-Blind Method; Humans; Hypertension; Indans; Male; Methionine; Middle Aged; Natriuretic Peptide, Brain; Neprilysin; Nerve Tissue Proteins; Posture; Propionates; Time Factors | 1993 |
Chronic inhibition of endopeptidase 24.11 in essential hypertension: evidence for enhanced atrial natriuretic peptide and angiotensin II.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Hypertension; Indans; Kidney; Male; Middle Aged; Natriuresis; Neprilysin; Propionates; Time Factors | 1993 |
Decreased angiotensin II response but unaltered cardiovascular pressor response to infused norepinephrine after sodium restriction and converting enzyme inhibition.
Topics: Adult; Analysis of Variance; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restricted; Double-Blind Method; Heart Rate; Humans; Hypertension; Male; Middle Aged; Neuropeptide Y; Norepinephrine | 1993 |
Humoral and haemodynamic effects of idrapril calcium, the prototype of a new class of ACE-inhibitors, in essential hypertensive patients.
Topics: Absorption; Administration, Oral; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hydroxylamines; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A | 1995 |
Renal extraction of atrial natriuretic peptide in hypertensive patients with or without renal artery stenosis.
Topics: Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Female; Humans; Hypertension; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Kidney; Male; Middle Aged; Radiography; Renal Artery; Renal Veins; Renin | 1996 |
Stimulatory effect of insulin on tubular sodium reabsorption in normotensive subjects with a positive family history of hypertension.
Topics: Adult; Angiotensin II; Blood Glucose; Female; Glucose Clamp Technique; Hemodynamics; Humans; Hyperinsulinism; Hypertension; Insulin; Insulin Resistance; Kidney Tubules; Male; Middle Aged; Pedigree; Potassium; Sodium; Vasoconstrictor Agents | 1996 |
Quinapril ACE-inhibition effects on adrenergic parameters in moderate essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Catecholamines; Electrocardiography; Female; Hemodynamics; Humans; Hypertension; Isoquinolines; Male; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Quinapril; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Tetrahydroisoquinolines | 1996 |
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Peptide Fragments; Time Factors | 1996 |
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine.
Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Dizziness; Double-Blind Method; Drug Administration Schedule; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1996 |
Effects of losartan on renal function in patients with essential hypertension.
Topics: Albuminuria; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Imidazoles; Kidney; Losartan; Male; Middle Aged; Renal Circulation; Single-Blind Method; Sodium; Tetrazoles; Uric Acid | 1996 |
Left ventricular diastolic function during adrenergic stress in essential hypertension: acute and chronic effects of ACE inhibition.
Topics: Adult; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Cold Temperature; Electrocardiography; Female; Humans; Hypertension; Linear Models; Lisinopril; Male; Middle Aged; Renin-Angiotensin System; Stroke Volume; Ventricular Function, Left | 1996 |
Platelet angiotensin II receptor status during pregnancy in Chinese women at high-risk of developing pregnancy-induced hypertension.
Topics: Adolescent; Adult; Angiotensin II; Aspirin; Blood Platelets; Calcium; Cohort Studies; Female; Food, Fortified; Hong Kong; Humans; Hypertension; Iodine Radioisotopes; Patient Selection; Platelet Aggregation Inhibitors; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Receptors, Angiotensin | 1996 |
Interruption of prolonged ramipril treatment in hypertensive patients: effects on the renin-angiotensin system.
Topics: Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Peptidyl-Dipeptidase A; Potassium; Ramipril; Renin; Renin-Angiotensin System | 1996 |
Comparison of the angiotensin II antagonist losartan with the angiotensin converting enzyme inhibitor enalapril in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Blood Pressure; Cough; Diastole; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Systole; Tetrazoles | 1995 |
Antihypertensive effects and arterial haemodynamic alterations during angiotensin converting enzyme inhibition.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Isoquinolines; Kidney Failure, Chronic; Male; Middle Aged; Tetrahydroisoquinolines | 1996 |
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril.
Topics: Adult; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 1996 |
The effects of angiotensin II receptor blockade with losartan on systemic blood pressure and renal and extrarenal prostaglandin synthesis in women with essential hypertension.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Female; Humans; Hypertension; Imidazoles; Kidney; Losartan; Middle Aged; Prostaglandins; Renin; Single-Blind Method; Tetrazoles; Uric Acid | 1995 |
Treatment of non-insulin-dependent diabetic hypertensive patients with Ca2+ channel blockers is associated with increased platelet sensitivity to insulin.
Topics: Angiotensin II; Antihypertensive Agents; Blood Platelets; Blood Pressure; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Isradipine; Male; Middle Aged; Vasoconstrictor Agents | 1995 |
[The first clinical experience in Italy with angiotensin II receptor antagonists: results of a multicenter study on the efficacy and tolerance in arterial hypertension].
Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Italy; Losartan; Male; Middle Aged; Tetrazoles | 1995 |
Captopril does not blunt the sympathoadrenal response to cigarette smoking in normotensive humans.
Topics: Adrenal Medulla; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cross-Over Studies; Double-Blind Method; Epinephrine; Female; Humans; Hypertension; Male; Norepinephrine; Placebos; Renin; Renin-Angiotensin System; Smoking; Sympathetic Nervous System | 1997 |
Effects of angiotensin-II infusion at pressor and subpressor doses on endothelin-1 plasma levels in healthy men.
Topics: Adult; Angiotensin II; Endothelin-1; Humans; Hypertension; Male; Reference Values | 1997 |
Effect of high-performance liquid chromatography on plasma angiotensin II measurements in treated and untreated normotensive and hypertensive patients.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Chemical Analysis; Blood Pressure; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Hypertension; Irbesartan; Radioimmunoassay; Renin; Sensitivity and Specificity; Tetrazoles | 1997 |
The Losartan Intervention For Endpoint reduction (LIFE) in Hypertension study: rationale, design, and methods. The LIFE Study Group.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Losartan; Male; Middle Aged; Research Design; Tetrazoles; Treatment Outcome | 1997 |
[ACE inhibitors and renal insufficiency].
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Kidney Failure, Chronic | 1997 |
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy, tolerability and safety compared to an angiotensin-converting enzyme inhibitor, lisinopril.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Male; Middle Aged; Safety; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1997 |
[AT1 angiotensin receptor inhibition as a new therapeutic possibility].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Female; Heart Failure; Humans; Hypertension; Losartan; Renin-Angiotensin System | 1997 |
Effects and tolerability of irbesartan versus enalapril in patients with severe hypertension. Irbesartan Multicenter Investigators.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Single-Blind Method; Tetrazoles | 1997 |
Blood pressure and endocrine effects of single doses of CS-866, a novel angiotensin II antagonist, in salt-restricted hypertensive patients.
Topics: Administration, Oral; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Radioimmunoassay; Renin; Safety; Tetrazoles; Treatment Outcome | 1997 |
The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators.
Topics: Adult; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Bosentan; Creatinine; Double-Blind Method; Endothelin Receptor Antagonists; Endothelin-1; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sulfonamides | 1998 |
The antihypertensive effect and tolerability of candesartan cilexetil, a new generation angiotensin II antagonist, in comparison with losartan.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome | 1998 |
Circulating plasma prekallikrein and tissue kallikrein in normotensive and hypertensive humans: effects of angiotensin II infusion.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Infusions, Intravenous; Kallikreins; Middle Aged; Prekallikrein; Reference Values; Renin | 1998 |
Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressure; Coronary Vessels; Cross-Over Studies; Cyclohexanecarboxylic Acids; Enalapril; Endothelin-1; Humans; Hypertension; Injections, Intra-Arterial; Male; Middle Aged; Myocardium; Neprilysin; Peptides, Cyclic; Protease Inhibitors; Renin; Single-Blind Method; Thiorphan; Vasoconstriction | 1998 |
[Effect of anti-atherosclerotic diet with polyunsaturated fatty acids omega-3 from linseed oil on dynamics of natural antibodies to bradykinin and angiotensin II in blood serum of patients with cardiovascular diseases].
Topics: Adult; Angiotensin II; Antibodies; Arteriosclerosis; Bradykinin; Cardiovascular Diseases; Fatty Acids, Omega-3; Female; Humans; Hyperlipoproteinemias; Hypertension; Linseed Oil; Male; Middle Aged; Myocardial Ischemia | 1998 |
Angiotensinogen genotype, sodium reduction, weight loss, and prevention of hypertension: trials of hypertension prevention, phase II.
Topics: Adult; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Genotype; Humans; Hypertension; Incidence; Male; Middle Aged; Promoter Regions, Genetic; Sodium, Dietary; United States; Weight Loss | 1998 |
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial of cardiovascular events in hypertension. Rationale and design.
Topics: Aged; Amlodipine; Angiotensin II; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Prospective Studies; Research Design; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
ACE inhibition but not angiotensin II antagonism reduces plasma fibrinogen and insulin resistance in overweight hypertensive patients.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Female; Fibrinogen; Hemodynamics; Humans; Hypertension; Indoles; Insulin Resistance; Losartan; Male; Middle Aged; Obesity; Perindopril | 1998 |
Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
Acute effects of candesartan cilexetil (the new angiotensin II antagonist) on systemic and renal haemodynamics in hypertensive patients.
Topics: Acute-Phase Reaction; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Prodrugs; Renal Circulation; Renin; Tetrazoles; Vasodilation | 1998 |
Valsartan and hydrochlorothiazide in patients with essential hypertension. A multiple dose, double-blind, placebo controlled trial comparing combination therapy with monotherapy.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Headache; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
Response of serum total renin to ramipril and metoprolol in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cross-Over Studies; Humans; Hypertension; Male; Metoprolol; Middle Aged; Peptidyl-Dipeptidase A; Ramipril; Renin | 1998 |
Pharmacokinetics and pharmacodynamics of candesartan cilexetil in patients with normal to severely impaired renal function.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Prodrugs; Renin; Tetrazoles | 1999 |
Effect of long-term eprosartan versus enalapril antihypertensive therapy on left ventricular mass and coronary flow reserve in stage I-II hypertension. Eprosartan Study Group.
Topics: Acrylates; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronary Circulation; Double-Blind Method; Enalapril; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Thiophenes | 1999 |
Effect of eprosartan and enalapril in the treatment of elderly hypertensive patients: subgroup analysis of a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
Topics: Acrylates; Age Factors; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Consumer Product Safety; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Thiophenes | 1999 |
Effects of eprosartan versus enalapril in hypertensive patients on the renin-angiotensin-aldosterone system and safety parameters: results from a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
Topics: Acrylates; Adult; Aged; Aged, 80 and over; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Consumer Product Safety; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Renin; Thiophenes | 1999 |
Effect of eprosartan and enalapril in the treatment of black hypertensive patients: subgroup analysis of a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group.
Topics: Acrylates; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Consumer Product Safety; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes | 1999 |
The state and responsiveness of the renin-angiotensin-aldosterone system in patients with type II diabetes mellitus.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Diabetes Mellitus, Type 2; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Renin-Angiotensin System; Vasoconstrictor Agents; Zona Glomerulosa | 1999 |
Angiotensin II stimulates left ventricular hypertrophy in hypertensive patients independently of blood pressure.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Echocardiography; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney; Male; Reference Values; Regional Blood Flow; Vasoconstrictor Agents | 1999 |
Assessment of once-daily eprosartan, an angiotensin II antagonist, in patients with systemic hypertension. Eprosartan Study Group.
Topics: Acrylates; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Placebos; Prospective Studies; Sex Factors; Thiophenes | 1999 |
Dose-response efficacy of valsartan, a new angiotensin II receptor blocker.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
Adenosine causes the release of active renin and angiotensin II in the coronary circulation of patients with essential hypertension.
Topics: Acetylcholine; Adenosine; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Cardiac Catheterization; Coronary Circulation; Dose-Response Relationship, Drug; Female; Forearm; Hemodynamics; Humans; Hypertension; Infusions, Intra-Arterial; Laser-Doppler Flowmetry; Male; Middle Aged; Nitroprusside; Renin; Renin-Angiotensin System | 1999 |
[Diovan efficacy and tolerance in mild and moderate hypertension].
Topics: Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Safety; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1999 |
Altered adrenal sensitivity to angiotensin II in low-renin essential hypertension.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Black People; Demography; Female; Humans; Hypertension; Male; Middle Aged; Renin; Vasoconstrictor Agents; White People | 1999 |
Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Diuretics; Drug Interactions; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Organ Size; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Research Design; Tetrazoles; Valine; Valsartan | 1999 |
High plasma renin activity is combined with elevated urinary albumin excretion in essential hypertensive patients.
Topics: Adult; Aged; Albuminuria; Angiotensin II; Blood Pressure; Creatinine; Female; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Renin; Renin-Angiotensin System; Sodium Chloride | 1999 |
Angiotensin II blunts, while an angiotensin-converting enzyme inhibitor augments, reflex sympathetic inhibition in humans.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Baroreflex; Captopril; Cardiovascular Physiological Phenomena; Female; Humans; Hypertension; Imidazoles; Imidazolidines; Male; Middle Aged; Renin; Sympathetic Nervous System | 1999 |
Comparison of angiotensin II receptor blockers: impact of missed doses of candesartan cilexetil and losartan in systemic hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Data Interpretation, Statistical; Drug Administration Schedule; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Middle Aged; Patient Compliance; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome | 1999 |
Alterations in angiotensin II release and vascular reactivity in hypertensive men: a pilot study.
Topics: Adult; Angiotensin II; Blood Glucose; Cold Temperature; Endothelin-1; Endothelium, Vascular; Femoral Artery; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypertension; Indocyanine Green; Insulin; Male; Norepinephrine; Pilot Projects; Vascular Resistance; Vasoconstrictor Agents | 1999 |
Effects of angiotensin converting enzyme and angiotensin II receptor inhibition on impaired fibrinolysis in systemic hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Female; Fibrinolysis; Fibrinolytic Agents; Humans; Hypertension; Lipoproteins; Losartan; Male; Middle Aged; Perindopril; Plasminogen Activator Inhibitor 1; Thrombomodulin; Tissue Plasminogen Activator | 1999 |
Captopril prevention project--what shall we do about captopril and the risk of stroke?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Brain Ischemia; Captopril; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stroke | 2000 |
Assessment of angiotensin II receptor blockade in humans using a standardized angiotensin II receptor-binding assay.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Irbesartan; Losartan; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reproducibility of Results; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 1999 |
The effect of amlodipine and enalapril on blood pressure and neurohumoral activation in hypertensive patients with Ribbing's disease (multiple epiphysal dystrophy).
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Enalapril; Heart Rate; Humans; Hypertension; Norepinephrine; Osteochondrodysplasias | 2000 |
A pharmacokinetic and pharmacodynamic study of the potential drug interaction between tasosartan and atenolol in patients with stage 1 and 2 essential hypertension.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Atenolol; Drug Synergism; Humans; Hypertension; Middle Aged; Pyrimidines; Single-Blind Method; Tetrazoles | 2000 |
The efficacy and tolerability of losartan versus atenolol in patients with isolated systolic hypertension. Losartan ISH Investigators Group.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Systole; Treatment Outcome | 2000 |
Renal haemodynamics and sodium excretory capacity during urapidil treatment in patients with essential hypertension.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Biomarkers; Catecholamines; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Piperazines; Renal Circulation; Renal Plasma Flow; Renin; Severity of Illness Index; Sodium | 2000 |
Pilot study of combined blockade of the renin-angiotensin system in essential hypertensive patients.
Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Pilot Projects; Renin-Angiotensin System; Treatment Outcome | 2000 |
Antihypertensive effect of valyl-tyrosine, a short chain peptide derived from sardine muscle hydrolyzate, on mild hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Dipeptides; Double-Blind Method; Female; Fishes; Humans; Hydrolysis; Hypertension; Male; Middle Aged; Muscles; Reference Values | 2000 |
Tasosartan and hydroclorothiazide as combination therapy in the treatment of severe essential hypertension: comparison with enalapril. Tasosartan Study Group.
Topics: Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Middle Aged; Pyrimidines; Tetrazoles | 2000 |
The effects of verapamil SR and bisoprolol on reducing the sympathetic nervous system's activity.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Endothelin-1; Epinephrine; Female; Hand Strength; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sympathetic Nervous System; Sympatholytics; Verapamil | 2000 |
Transforming growth factor beta in hypertensives with cardiorenal damage.
Topics: Albuminuria; Angiotensin II; Antihypertensive Agents; Collagen; Collagen Type I; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Peptide Fragments; Peptides; Procollagen; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome | 2000 |
Influence of angiotensin II type 1 receptor polymorphism on hypertension in patients with hypercholesterolemia.
Topics: Aged; Alleles; Angiotensin II; Base Sequence; DNA Primers; Female; Gene Frequency; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Receptors, Angiotensin | 2001 |
Impaired sodium excretion during mental stress in mild essential hypertension.
Topics: Adolescent; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cross-Over Studies; Double-Blind Method; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Natriuresis; Renal Circulation; Sodium; Stress, Physiological | 2001 |
Quinaprilat-induced vasodilatation in forearm vasculature of patients with essential hypertension: comparison with enalaprilat.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Enalaprilat; Forearm; Heart Rate; Humans; Hypertension; Isoquinolines; Male; Middle Aged; Peptidyl-Dipeptidase A; Regional Blood Flow; Tetrahydroisoquinolines; Vasodilation | 2000 |
Blood pressure response to angiotensin II, low-density lipoprotein cholesterol and polymorphisms of the angiotensin II type 1 receptor gene in hypertensive sibling pairs.
Topics: Adult; Aging; Angiotensin II; Blood Pressure; Cholesterol, LDL; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Nuclear Family; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sex Characteristics; White People | 2001 |
Effect of salt intake on endothelium-derived factors in a group of patients with essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure Monitoring, Ambulatory; Cyclic GMP; Diet, Sodium-Restricted; Endothelins; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitrites; Normal Distribution; Renin; Single-Blind Method; Sodium Chloride, Dietary; Statistics, Nonparametric | 2001 |
Differential effects of ACE-inhibition and angiotensin II antagonism on fibrinolysis and insulin sensitivity in hypertensive postmenopausal women.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood Pressure; Double-Blind Method; Female; Fibrinolysis; Humans; Hypertension; Indoles; Insulin; Insulin Resistance; Lipids; Losartan; Middle Aged; Plasminogen Activator Inhibitor 1; Postmenopause; Sensitivity and Specificity; Women's Health | 2001 |
Angiotensin in cardiac surgery: efficacy in patients on angiotensin converting enzyme inhibitors.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiac Surgical Procedures; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Phenylephrine; Vascular Resistance; Vasoconstrictor Agents | 2001 |
Inhibitory effect of telmisartan on the blood pressure response to angiotensin II challenge.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Area Under Curve; Benzimidazoles; Benzoates; Blood Pressure; Double-Blind Method; Headache; Humans; Hypertension; Male; Plethysmography; Pulse; Telmisartan | 2001 |
Long-term effects of olmesartan, an Ang II receptor antagonist, on blood pressure and the renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Pulse; Renin; Renin-Angiotensin System; Respiration Disorders; Tetrazoles; Time Factors | 2001 |
[Effect of yimai jiangya extract on platelet activation and fibrinolytic activity and angiotensin II in aged patients with essential hypertension].
Topics: Aged; Angiotensin II; Drugs, Chinese Herbal; Female; Fibrinolytic Agents; Humans; Hypertension; Male; Middle Aged; P-Selectin; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Tissue Plasminogen Activator | 2000 |
Effects of losartan and its combination with quinapril on the cardiac sympathetic nervous system and neurohormonal status in essential hypertension.
Topics: 3-Iodobenzylguanidine; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Therapy, Combination; Female; Heart; Hemodynamics; Humans; Hypertension; Isoquinolines; Losartan; Male; Middle Aged; Quinapril; Radionuclide Imaging; Radiopharmaceuticals; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Tetrahydroisoquinolines; Treatment Outcome | 2002 |
Stimulation of cardiac apoptosis in essential hypertension: potential role of angiotensin II.
Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Calcium Channel Blockers; Female; Heart Ventricles; Humans; Hypertension; Losartan; Male; Middle Aged; Myocardium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptor, Angiotensin, Type 1 | 2002 |
Changes in renal and systemic hemodynamics after NO-synthase inhibition in males with family history of hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Double-Blind Method; Endothelin-1; Enzyme Inhibitors; Heart Rate; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Male; Medical Records; Natriuresis; Nitric Oxide Synthase; omega-N-Methylarginine; Renal Circulation; Renin | 2002 |
Angiotensin II type 1 receptor antagonist, losartan, causes regression of left ventricular hypertrophy in end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Echocardiography; Enalapril; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Dialysis | 2002 |
Angiotensin II receptor-independent antiinflammatory and antiaggregatory properties of losartan: role of the active metabolite EXP3179.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arachidonic Acid; Biotransformation; Cells, Cultured; Cyclooxygenase 2; Dinoprost; Drug Design; Endothelium, Vascular; Enzyme Activation; Female; Humans; Hypertension; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; Isoenzymes; Lipopolysaccharides; Losartan; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Thromboxane A2; Up-Regulation; Vasoconstrictor Agents | 2002 |
Reduction in arterial stiffness with angiotensin II antagonist is comparable with and additive to ACE inhibition.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Blood Pressure; Captopril; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Humans; Hypertension; Middle Aged; Pulse; Tetrazoles; Valine; Valsartan | 2002 |
Angiotensinogen genotype affects renal and adrenal responses to angiotensin II in essential hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Antihypertensive Agents; Female; Genotype; Humans; Hypertension; Kidney; Male; Middle Aged; Models, Biological; Renal Plasma Flow | 2002 |
Angiotensin-II receptor antagonist losartan reduces microalbuminuria in hypertensive renal transplant recipients.
Topics: Adolescent; Adult; Albuminuria; Angiotensin II; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Kidney Transplantation; Losartan; Male; Middle Aged | 2002 |
The impact of angiotensin II receptor blockade and the DASH diet on markers of endogenous fibrinolysis.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Diet, Sodium-Restricted; Female; Fibrinolysis; Humans; Hypertension; Losartan; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Renin; Tissue Plasminogen Activator | 2002 |
[Blood pressure, renin, angiotension II and catecholamines in the plasma of healthy subjects and patients with essential hypertension before and after beta blockade].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Placebos; Renin | 1976 |
Long-term effects of captopril (SQ14 225) on blood-pressure and hormone levels in essential hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Proline; Renin | 1979 |
Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Proline; Renin | 1979 |
Renin-aldosterone profiling in hypertension.
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Clinical Trials as Topic; Diagnosis, Differential; Diuretics; Dopamine beta-Hydroxylase; Humans; Hyperaldosteronism; Hypertension; Norepinephrine; Propranolol; Renin; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1977 |
Combination hypotensive therapy with atenolol, bendrofluazide and hydrallazine.
Topics: Angiotensin II; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Male; Propanolamines; Renin | 1977 |
[Results obtained using a combination of a beta blockader (sotalol) and a diuretic in the treatment of arterial hypertension].
Topics: Angiotensin II; Chlorthalidone; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Humans; Hypertension; Placebos; Renin; Sotalol | 1977 |
Response of blood pressure and the renin-angiotensin-aldosterone axis to hypotensive therapy: comparison of propranolol with spironolactone.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Propranolol; Renin; Spironolactone | 1977 |
[Spironolactone-induced changes of the renin-angiotensin-aldosterone system and blood pressure lowering in essential hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Humans; Hypertension; Renin; Spironolactone | 1977 |
A comparison between spironolactone and hydrochlorothiazide with and without alpha-methyldopa in the treatment of hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Renin; Spironolactone | 1978 |
Haemodynamic profile of angiotensin II antagonism in essential hypertensive patients.
Topics: Adult; Angiotensin II; Angiotensins; Blood Pressure; Cardiac Output; Heart Rate; Humans; Hypertension; Male; Renin; Saralasin | 1979 |
Haemodynamic effects of captopril in hypertensive patients: comparison with saralasin.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Cardiac Output; Clinical Trials as Topic; Heart Rate; Humans; Hypertension; Oxygen Consumption; Placebos; Proline; Renin; Saralasin; Stroke Volume; Vascular Resistance | 1979 |
Does the renin-angiotensin system maintain blood pressure in both hypertensive and normotensive subjects? A comparison of propranolol, saralasin and captopril.
Topics: Angiotensin II; Angiotensins; Blood Pressure; Captopril; Humans; Hypertension; Male; Proline; Propranolol; Reference Values; Renin; Saralasin | 1979 |
The influence of sar1 ala8 angiotensin II (saralasin) on plasma aldosterone in hypertensive patients.
Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renovascular; Infusions, Parenteral; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Renin; Saralasin; Sodium | 1979 |
[Effect of bupranolol on the renin-angiotensin system in essential hypertension].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Propanolamines; Renin | 1978 |
Controlled treatment of primary hypertension with propranolol and spironolactone. A crossover study with special reference to initial plasma renin activity.
Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Posture; Potassium; Propranolol; Renin; Sodium; Spironolactone | 1976 |
Effect of blood pressure angiotensin II and aldosterone concentrations during treatment of severe hypertension with intravenous labetalol: comparison with propranolol.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Heart Rate; Humans; Hypertension; Injections, Intravenous; Labetalol; Propranolol | 1976 |
Differential effects of acute and chronic beta-adrenoreceptor blockade on blood pressure and the renin-angiotensin-aldosterone system in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Humans; Hypertension; Male; Pindolol; Propranolol; Renin | 1976 |
Effect of sotalol on haemodynamics and renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Renin; Sotalol | 1976 |
Dissociation of blood angiotensin II and plasma renin activity during chronic treatment in essential hypertension.
Topics: Angiotensin II; Diuretics; Humans; Hypertension; Renin; Time Factors | 1976 |
Effects of intravenous labetalol on blood pressure, angiotensin II and aldosterone in hypertension: comparison with propranolol.
Topics: Aldosterone; Angiotensin II; Depression, Chemical; Ethanolamines; Heart Rate; Humans; Hypertension; Labetalol; Propranolol | 1976 |
Aldosterone and renin in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adult; Age Factors; Aldosterone; Angiotensin II; Clinical Trials as Topic; Endopeptidases; Furosemide; Hemodynamics; Humans; Hypertension; Liver Circulation; Metabolic Clearance Rate; Middle Aged; Receptors, Adrenergic; Renin; Secretory Rate; Sodium | 1975 |
Contraceptive steroids and hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Deoxycholic Acid; Female; Humans; Hydrocortisone; Hypertension; Renin; Time Factors | 1975 |
Clinical experience with angiotensin II receptor antagonists.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Injections, Intravenous; Losartan; Renin-Angiotensin System; Tetrazoles; Time Factors | 1992 |
Coronary haemodynamic effects of angiotensin II in mild essential hypertension in man.
Topics: Adult; Angiotensin II; Blood Pressure; Coronary Circulation; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hypertension; Isometric Contraction; Male; Middle Aged; Renin-Angiotensin System | 1992 |
Partial escape of angiotensin converting enzyme (ACE) inhibition during prolonged ACE inhibitor treatment: does it exist and does it affect the antihypertensive response?
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Drug Administration Schedule; Enalapril; Female; Hemodynamics; Humans; Hypertension; Male; Peptidyl-Dipeptidase A; Single-Blind Method; Time Factors | 1992 |
Effects of a new calcium antagonist, manidipine, on the renal hemodynamics and the vasoactive humoral factors in patients with diabetes mellitus.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus; Dihydropyridines; Endothelins; Female; Humans; Hypertension; Male; Middle Aged; Nitrobenzenes; Piperazines; Renal Circulation | 1992 |
Effect of isradipine on cardiopulmonary baroreflex function, regional blood flow, and vascular responsiveness in hypertensive patients.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Hemodynamics; Humans; Hypertension; Isradipine; Male; Middle Aged; Norepinephrine; Pressoreceptors; Reflex; Regional Blood Flow | 1992 |
Histopathological evaluation on the effect of induced hypertension chemotherapy presurgically performed in patients with advanced carcinoma of the stomach.
Topics: Adenocarcinoma; Adult; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Humans; Hypertension; Male; Middle Aged; Stomach Neoplasms | 1992 |
Hypertension in pregnancy.
Topics: Angiotensin II; Aspirin; Blood Flow Velocity; Female; Fetus; Humans; Hypertension; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Ultrasonography, Prenatal | 1992 |
Modulation of noradrenergic but not angiotensinergic blood pressure control by beta-blockade with carteolol.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Carteolol; Female; Humans; Hypertension; Isoproterenol; Male; Norepinephrine; Receptors, Adrenergic, beta; Single-Blind Method | 1991 |
Vascular pressor responses in treated and untreated essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Doxazosin; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Peptidyl-Dipeptidase A; Phenylephrine; Prazosin; Reflex; Regional Blood Flow; Renin | 1990 |
Nonparallel effects of renin inhibitor treatment on plasma renin activity and angiotensins I and II in hypertensive subjects. An assay-related artifact.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1991 |
Effect of the circulating renin-angiotensin system on prolactin release in humans.
Topics: Adenoma; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Circadian Rhythm; Enalapril; Humans; Hypertension; Prolactin; Renin; Renin-Angiotensin System; Thyrotropin-Releasing Hormone | 1990 |
Natriuresis-pressure relationship in polycystic kidney disease.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Natriuresis; Polycystic Kidney Diseases; Receptors, Angiotensin; Sodium, Dietary | 1990 |
Beta-adrenergic receptor sensitivity during sodium restriction and converting enzyme inhibition.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Combined Modality Therapy; Cyclic AMP; Diet, Sodium-Restricted; Double-Blind Method; Heart Rate; Humans; Hypertension; Isoproterenol; Male; Norepinephrine; Randomized Controlled Trials as Topic; Receptors, Adrenergic, beta; Renin; Sympathetic Nervous System | 1990 |
Influence of captopril on urinary excretion of furosemide in hypertensive subjects.
Topics: Adult; Aged; Angiotensin II; Captopril; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Premedication; Random Allocation; Renin; Time Factors | 1990 |
Prolonged blood pressure reduction by orally active renin inhibitor RO 42-5892 in essential hypertension.
Topics: Administration, Oral; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Drug Evaluation; Humans; Hypertension; Imidazoles; Injections, Intravenous; Male; Middle Aged; Renin; Time Factors | 1990 |
Effect of furosemide on angiotensin II-mediated prostaglandin I2 production in hypertensive subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angiotensin II; Captopril; Dinoprostone; Double-Blind Method; Epoprostenol; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin | 1990 |
Nisoldipine--effects on the renin-angiotensin-aldosterone system and catecholamines. Studies in normotensive and hypertensive subjects.
Topics: Angiotensin II; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Nisoldipine; Norepinephrine; Renin-Angiotensin System; Time Factors | 1990 |
Antihypertensive and renal effects of enalapril and slow-release verapamil in essential hypertension. A double-blind, randomized study.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Renin; Verapamil | 1990 |
Chronic treatment of hypertensive patients with converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cerebrovascular Circulation; Clinical Trials as Topic; Coronary Circulation; Enalapril; Heart Rate; Humans; Hypertension; Lipids; Oligopeptides; Peptidyl-Dipeptidase A; Potassium; Rats; Rats, Inbred SHR; Renin; Sodium; Teprotide | 1986 |
Endocrine and vascular responses in hypertensive patients to long-term treatment with diltiazem.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Body Weight; Diltiazem; Dinoprostone; Endocrine Glands; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prostaglandins E; Pulse; Renin | 1987 |
Acute antihypertensive effect of angiotensin converting enzyme inhibition and calcium entry blockade.
Topics: Adult; Angiotensin II; Blood Pressure; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Peptidyl-Dipeptidase A | 1987 |
Acute calcium entry blockade inhibits the blood pressure but not the hormonal responses to angiotensin II.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Heart Rate; Humans; Hydrocortisone; Hypertension; Isradipine; Middle Aged; Norepinephrine; Pyridines; Renin | 1989 |
Large and small forearm arteries of essential hypertensives are less reactive to angiotensin II than to noradrenaline.
Topics: Angiotensin II; Arteries; Blood Pressure; Dose-Response Relationship, Drug; Forearm; Heart Rate; Humans; Hypertension; Norepinephrine; Vascular Resistance | 1989 |
Twice-daily low-dose captopril in diuretic-treated hypertensives.
Topics: Adult; Aged; Angiotensin II; Benzothiadiazines; Captopril; Diuretics; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Renin; Sodium; Sodium Chloride Symporter Inhibitors | 1989 |
Hypertensive dysregulation and its modification by calcium channel blockade in nonoliguric renal failure.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Catecholamines; Creatinine; Electrolytes; Heart Rate; Humans; Hypertension; Isoproterenol; Kidney Failure, Chronic; Middle Aged; Nitrendipine; Norepinephrine; Renin | 1989 |
Beneficial and adverse effects of angiotensin converting enzyme inhibitors.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypertension; Kinins; Rats | 1989 |
Crossover design for the dose determination of an angiotensin converting enzyme inhibitor in hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure Determination; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Renin | 1989 |
Cardiovascular regulation and lipoprotein profile during administration of co-dergocrine in essential hypertension.
Topics: Adult; Aged; Angiotensin II; Antihypertensive Agents; Dihydroergotoxine; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Isoproterenol; Lipoproteins; Male; Middle Aged; Norepinephrine; Renal Circulation | 1989 |
Antihypertensive and hypouricaemic effects of nitrendipine in chronic renal failure.
Topics: Adult; Aged; Angiotensin II; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nitrendipine; Risk Factors; Uric Acid | 1989 |
Treatment of hypertension with enalapril and hydrochlorothiazide or enalapril and atenolol: contrasts in hypotensive interactions.
Topics: Angiotensin II; Atenolol; Atrial Natriuretic Factor; Double-Blind Method; Drug Therapy, Combination; Enalapril; Factor Analysis, Statistical; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Random Allocation; Renin | 1987 |
Evolution of angiotensin-converting enzyme inhibitors.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Drug Design; Enalapril; Heart Failure; Humans; Hypertension; Renin-Angiotensin System | 1988 |
Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae.
Topics: Adolescent; Adult; Angiotensin II; Aspirin; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Infant, Newborn; Infusions, Parenteral; Male; Malondialdehyde; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Random Allocation | 1986 |
Hormonal and blood pressure responses to tilting in beta-blocked essential hypertension treated with felodipine or prazosin.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitrendipine; Prazosin; Pulse; Renin; Vasopressins | 1987 |
Renal haemodynamic and neurohumoral responses to urapidil in hypertensive man.
Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Clinical Trials as Topic; Humans; Hypertension; Iodine Radioisotopes; Neurotransmitter Agents; Piperazines; Random Allocation; Renal Circulation; Renin; Time Factors | 1988 |
First dose response and 24-hour antihypertensive efficacy of the new once-daily angiotensin converting enzyme inhibitor, ramipril.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Ramipril; Time Factors | 1988 |
Converting enzyme inhibition in mild and moderate essential hypertension. I. Acute effects on blood pressure, the renin-angiotensin system and blood bradykinin after a single dose of captopril.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1985 |
Double-blind comparison of captopril and enalapril in mild to moderate hypertension.
Topics: Adult; Angiotensin II; Benzothiadiazines; Blood Pressure; Captopril; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Random Allocation; Renin; Sodium Chloride Symporter Inhibitors | 1986 |
Humoral effects of long-term oral enalapril therapy.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Blood Pressure; Blood Specimen Collection; Clinical Trials as Topic; Drug Therapy, Combination; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Longitudinal Studies; Potassium; Pulse; Random Allocation; Renin; Renin-Angiotensin System | 1986 |
Enhanced response of plasma prolactin to metoclopramide during chronic converting enzyme inhibition.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Enalapril; Female; Humans; Hypertension; Male; Metoclopramide; Middle Aged; Prolactin; Renin | 1987 |
Effect of nicardipine on angiotensin II platelet content.
Topics: Aged; Angiotensin II; Blood Platelets; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Time Factors | 1988 |
Effects of angiotensin and angiotensin blockade on coronary circulation and coronary reserve.
Topics: Adult; Angiotensin II; Blood Pressure; Captopril; Coronary Circulation; Exercise; Furosemide; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Oxygen Consumption; Renin-Angiotensin System; Vascular Resistance | 1988 |
Acute and chronic ketanserin in essential hypertension: antihypertensive mechanisms and pharmacokinetics.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Ketanserin; Male; Middle Aged; Norepinephrine; Phenylephrine; Prazosin; Renin | 1987 |
Effects of ketanserin on blood pressure and platelet aggregation in elderly men with mild hypertension.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Pressure; Calcium; Humans; Hypertension; Intracellular Membranes; Ketanserin; Male; Middle Aged; Osmolar Concentration; Phenylephrine; Platelet Aggregation | 1988 |
Effects of combined therapy with amiloride and hydrochlorothiazide on plasma and total body potassium, blood pressure, and the renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Amiloride; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Random Allocation; Renin; Renin-Angiotensin System | 1986 |
Potassium and norepinephrine- or angiotensin-mediated pressor control in pre-hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Norepinephrine; Potassium | 1987 |
Effect of sodium balance and calcium channel blocking drugs on blood pressure responses.
Topics: Adult; Angiotensin II; Blood Pressure; Calcium; Calcium Channel Blockers; Diet, Sodium-Restricted; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Sodium | 1987 |
Effect of captopril and hydrochlorothiazide on the response to pressor agents in hypertensives.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Proline | 1985 |
Effects of potassium on sodium balance, renin, noradrenaline and arterial pressure.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Condiments; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Potassium; Potassium Chloride; Renin; Sodium; Urea | 1985 |
Effect of verapamil on renal plasma flow, glomerular filtration rate and plasma angiotensin II, aldosterone and arginine vasopressin in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pressure; Body Weight; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Male; Middle Aged; Potassium; Renal Circulation; Sodium; Verapamil | 1985 |
[Renin, angiotensin II, catecholamines and blood pressure in healthy subjects and in patients with essential hypertension prior and following beta-blockade].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Blood Pressure; Catecholamines; Female; Humans; Hypertension; Male; Placebos; Renin | 1974 |
Antihypertensive actions of diuretics. Comparative study of an aldosterone antagonist and a thiazide, alone and together.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure Determination; Blood Volume Determination; Clinical Trials as Topic; Humans; Hydrochlorothiazide; Hypertension; Norepinephrine; Placebos; Potassium; Spironolactone | 1968 |
High blood pressure and oral contraceptives. Changes in plasma renin and renin substrate and in aldosterone excretion.
Topics: Aldosterone; Angiotensin II; Clinical Trials as Topic; Contraceptives, Oral; Ethinyl Estradiol; Female; Humans; Hypertension; Male; Norethynodrel; Plasma; Pregnancy; Renin | 1968 |
[Cardiomechanics and sphygmographic indices after injection of phentolamine in subjects with hypertension induced by angiotensin II. Polygraphic study].
Topics: Adult; Angiotensin II; Clinical Trials as Topic; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Male; Phentolamine; Pulse | 1967 |
[Variations in the renin-angiotensin-aldosterone system and in the antidiuretic hormone induced within 5 days by a contraceptive drug. Rapid action of a contraceptive drug on the hormones controlling water and salt metabolism].
Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Contraceptives, Oral; Ethinyl Estradiol; Female; Humans; Hypertension; Male; Middle Aged; Renin; Sodium Chloride; Vasopressins; Water | 1970 |
The effect of tyramine, noradrenaline, and angiotensin on the blood pressure in hypertensive patients with aldosteronism and low plasma renin.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Angiotensin II; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Norepinephrine; Pheochromocytoma; Renin; Tyramine; Vascular Resistance | 1970 |
Accurate and rapid measurement of plasma renin activity by radioimmunoassay. Results in normal and hypertensive people.
Topics: Angiotensin II; Clinical Trials as Topic; Humans; Hyperaldosteronism; Hypertension; Iodine Isotopes; Methods; Radioimmunoassay; Renal Artery Obstruction; Renin | 1971 |
18-Hydroxy-deoxycorticosterone in human hypertension.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood Pressure; Catheterization; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dexamethasone; Humans; Hypertension; Liver Extracts; Mass Spectrometry; Mineralocorticoids; Radioisotope Dilution Technique; Renin; Sodium; Spironolactone; Tritium | 1971 |
Effects of oral contraceptive therapy on the renin-angiotensin system.
Topics: Adult; Angiotensin II; Blood Pressure; Blood Volume; Cardiac Output; Clinical Trials as Topic; Contraceptives, Oral; Female; Humans; Hypertension; Iodine Isotopes; Menstruation; Middle Aged; Radioimmunoassay; Renin; Sodium; Water-Electrolyte Balance | 1971 |
Clinical evaluation of indoramin, a new antihypertensive agent.
Topics: Angiotensin II; Antihypertensive Agents; Benzamides; Blood Pressure; Body Weight; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Tolerance; Female; Heart Rate; Humans; Hypertension; Indoles; Isoproterenol; Male; Norepinephrine; Piperidines; Placebos; Regression Analysis; Time Factors | 1973 |
Effects of plasma from hypertensive patients on the responses to angiotensin and norepinephrine in dogs and rats.
Topics: Adult; Analysis of Variance; Angiotensin II; Animals; Blood; Blood Pressure; Blood Urea Nitrogen; Catecholamines; Creatinine; Dogs; Female; Humans; Hypertension; Male; Middle Aged; Nitroglycerin; Norepinephrine; Perfusion; Placebos; Rats; Thiazines; Tyramine; Vascular Resistance | 1974 |
Angiotensin infusion test in the diagnosis of renal hypertension.
Topics: Adult; Angiotensin Amide; Angiotensin II; Clinical Trials as Topic; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged | 1974 |
[The effect of guanethidine and reserpine in angiotensin sensitivity in man].
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Female; Guanethidine; Humans; Hypertension; Male; Middle Aged; Reserpine | 1974 |
5069 other study(ies) available for angiotensin ii and Hypertension
| Article | Year |
|---|---|
New losartan-hydrocaffeic acid hybrids as antihypertensive-antioxidant dual drugs: Ester, amide and amine linkers.
Topics: Amides; Amines; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta, Thoracic; Caffeic Acids; Cells, Cultured; Esters; Hypertension; Losartan; Male; Molecular Structure; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Structure-Activity Relationship; Vasoconstrictor Agents | 2012 |
Maternal Angiotensin II-Induced Hypertension Sensitizes Postweaning High-Fat Diet-Elicited Hypertensive Response Through Increased Brain Reactivity in Rat Offspring.
Topics: Angiotensin II; Animals; Brain; Diet, High-Fat; Female; Hypertension; Male; Pregnancy; Rats; Weaning | 2021 |
Baicalin attenuates angiotensin II-induced blood pressure elevation and modulates MLCK/p-MLC signaling pathway.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Calcium Signaling; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Flavonoids; Hypertension; Hypoglycemic Agents; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Rats, Wistar | 2021 |
Cross-Talk between TNF-α and Angiotensin II in the Neural Control of Hypertension.
Topics: Angiotensin II; Humans; Hypertension; Renin-Angiotensin System; Tumor Necrosis Factor-alpha | 2021 |
Overexpression of dimethylarginine dimethylaminohydrolase 1 protects from angiotensin II-induced cardiac hypertrophy and vascular remodeling.
Topics: Amidohydrolases; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Enzyme Induction; Fibrosis; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Transgenic; Time Factors; Vascular Remodeling; Vasodilation; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Growth Arrest Specific-6 and Axl Coordinate Inflammation and Hypertension.
Topics: Adult; Aged; Angiotensin II; Animals; Axl Receptor Tyrosine Kinase; Cells, Cultured; Dendritic Cells; Endothelial Cells; Female; Humans; Hypertension; Intercellular Adhesion Molecule-1; Intercellular Signaling Peptides and Proteins; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Middle Aged; Monocytes; NLR Family, Pyrin Domain-Containing 3 Protein; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases | 2021 |
Chronic 3D Vascular-Immune Interface Established by Coculturing Pressurized Resistance Arteries and Immune Cells.
Topics: Angiotensin II; Animals; Cell Movement; Coculture Techniques; Female; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Sex Characteristics; T-Lymphocytes; Vascular Resistance | 2021 |
Ang II-Induced Hypertension Exacerbates the Pathogenesis of Tuberculosis.
Topics: Angiotensin II; Animals; Apoptosis; Hypertension; Lung; Macrophages; Male; Mice; Mice, Inbred C57BL; Mycobacterium tuberculosis; Necrosis; Tuberculosis; Vasoconstrictor Agents | 2021 |
Long noncoding RNA p21 enhances autophagy to alleviate endothelial progenitor cells damage and promote endothelial repair in hypertension through SESN2/AMPK/TSC2 pathway.
Topics: Aged; AMP-Activated Protein Kinases; Angiotensin II; Animals; Autophagy; beta-Galactosidase; Cell Adhesion; Cell Movement; Endothelial Progenitor Cells; Female; Humans; Hypertension; Male; Middle Aged; Nuclear Proteins; Rats, Inbred SHR; Rats, Wistar; RNA, Long Noncoding; Tuberous Sclerosis Complex 2 Protein | 2021 |
Both central sympathoexcitation and peripheral angiotensin II-dependent vasoconstriction contribute to hypertension development in immature heterozygous Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Losartan; Male; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System; Vasoconstriction | 2022 |
2-Methoxyestradiol Ameliorates Angiotensin II-Induced Hypertension by Inhibiting Cytosolic Phospholipase A
Topics: 2-Methoxyestradiol; 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Collagen; Cytochrome P-450 CYP1A1; Female; Group IV Phospholipases A2; Hypertension; Mice; Reactive Oxygen Species; Receptors, Prostaglandin E, EP3 Subtype | 2021 |
Aqueous extract of Solanum nigrum attenuates Angiotensin-II induced cardiac hypertrophy and improves cardiac function by repressing protein kinase C-ζ to restore HSF2 deSUMOlyation and Mel-18-IGF-IIR signaling suppression.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiotonic Agents; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Heat-Shock Proteins; Hypertension; Male; Myoblasts, Cardiac; Plant Extracts; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, IGF Type 2; Solanum nigrum; Transcription Factors | 2022 |
Vascular smooth muscle cell-specific miRNA-214 knockout inhibits angiotensin II-induced hypertension through upregulation of Smad7.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Movement; Cell Proliferation; Cells, Cultured; Female; Gene Knockout Techniques; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Smad7 Protein; Up-Regulation; Vascular Remodeling | 2021 |
Interferon-stimulated gene 15 pathway is a novel mediator of endothelial dysfunction and aneurysms development in angiotensin II infused mice through increased oxidative stress.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Carotid Intima-Media Thickness; Elastin; Humans; Hypertension; Inflammation; Interferons; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2022 |
Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Choline O-Acetyltransferase; Disease Models, Animal; Heart Rate; Humans; Hypertension; Male; Mice, Inbred C57BL; Nitric Oxide; Polyethylene Glycols; Recombinant Proteins; Vasodilation | 2021 |
PKM2 promotes angiotensin-II-induced cardiac remodelling by activating TGF-β/Smad2/3 and Jak2/Stat3 pathways through oxidative stress.
Topics: Angiotensin II; Animals; Enzyme Inhibitors; Fibroblasts; Gene Expression; Hypertension; Janus Kinase 2; Male; Mice; Models, Biological; Oxidative Stress; Pyruvate Kinase; Reactive Oxygen Species; Smad2 Protein; Smad3 Protein; STAT3 Transcription Factor; Ventricular Remodeling | 2021 |
Role of plasma angiotensin II and angiotensin-converting enzyme 2 levels on prognosis and mortality in hypertensive patients with COVID-19.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Disease-Free Survival; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; SARS-CoV-2; Survival Rate | 2021 |
Biological evaluation of linalool on the function of blood vessels.
Topics: Acyclic Monoterpenes; Angiotensin II; Animals; Blood Vessels; Cell Line; Cell Movement; Cell Proliferation; Down-Regulation; Hypertension; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Rats; Receptor, Muscarinic M3; Signal Transduction | 2021 |
SIRT1 and Klotho expression in the heart and kidneys of rats with acute and chronic renovascular hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Glucuronidase; Hypertension; Hypertension, Renovascular; Kidney; Klotho Proteins; Rats; Sirtuin 1 | 2021 |
Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti-hypertension effect.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blood Pressure; Disease Models, Animal; Drugs, Chinese Herbal; Gene Knockdown Techniques; Heart Rate; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Vascular Remodeling | 2022 |
Hypertensive effects of transforming growth factor-β1 in vascular smooth muscles cells from spontaneously hypertensive rats are mediated by sulfatase 2.
Topics: Angiotensin II; Animals; Cells, Cultured; Hypertension; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Sulfatases; Transforming Growth Factor beta1 | 2022 |
Renal denervation inhibits the renin-angiotensin-aldosterone system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System | 2022 |
Morphology and cyclooxygenase-2 and renin expression in the kidney of young spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Creatinine; Cyclooxygenase 2; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Urea | 2022 |
Mechanisms of Flow-Mediated Dilation of Pial Collaterals and the Effect of Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Cerebrovascular Circulation; Collateral Circulation; Female; Hemodynamics; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Stress, Mechanical; Vasoconstrictor Agents; Vasodilation | 2022 |
Angptl2 gene knockdown is critical for abolishing angiotensin II-induced vascular smooth muscle cell proliferation and migration.
Topics: Angiopoietin-Like Protein 2; Angiopoietin-like Proteins; Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Gene Knockdown Techniques; Hypertension; Ki-67 Antigen; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY | 2022 |
Th17/Treg imbalance in patients with primary hyperaldosteronism and resistant hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure Monitoring, Ambulatory; Forkhead Transcription Factors; Humans; Hyperaldosteronism; Hypertension; Interleukin-17; T-Lymphocytes, Regulatory | 2022 |
Toll-like receptor 4 mutation protects the kidney from Ang-II-induced hypertensive injury.
Topics: Angiotensin II; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Hypertension; Kidney; Kidney Diseases; Male; Mice, Inbred C3H; Mice, Mutant Strains; Microtubule-Associated Proteins; Mutation; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2022 |
Marginolides A-B, polyether macrolide analogues from veined octopus
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Hypertension; Macrolides; Octopodiformes | 2022 |
Immunoneutralization of human angiotensin-(1-12) with a monoclonal antibody in a humanized model of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antibodies, Monoclonal; Blood Pressure; Female; Humans; Hypertension; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2022 |
Angiotensin Type 2 and Mas Receptor Activation Prevents Myocardial Fibrosis and Hypertrophy through the Reduction of Inflammatory Cell Infiltration and Local Sympathetic Activity in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Hypertension; Imidazoles; Injections, Intraperitoneal; Losartan; Male; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Tyrosine 3-Monooxygenase | 2021 |
Consequences of hyperandrogenemia during pregnancy in female offspring: attenuated response to angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Humans; Hyperandrogenism; Hypertension; Kidney; Male; Polycystic Ovary Syndrome; Pregnancy; Rats; Rats, Sprague-Dawley | 2022 |
CFTR deficiency aggravates Ang II induced vasoconstriction and hypertension by regulating Ca2+ influx and RhoA/Rock pathway in VSMCs.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Cystic Fibrosis Transmembrane Conductance Regulator; Hypertension; Mice; Mice, Inbred CFTR; Mice, Knockout; Muscle, Smooth, Vascular; Phosphorylation; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoconstriction | 2021 |
Angiotensin II Infusion Results in Both Hypertension and Increased AMPA GluA1 Signaling in Hypothalamic Paraventricular Nucleus of Male but not Female Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Male; Mice; Paraventricular Hypothalamic Nucleus | 2022 |
Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction.
Topics: Angiotensin II; Animals; Cyclic Nucleotide Phosphodiesterases, Type 4; Gene Expression Regulation, Enzymologic; Hypertension; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphodiesterase 4 Inhibitors; Rats; Rolipram | 2022 |
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Hypertension; Mice; Mice, Inbred C57BL; Myocardium; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Uncaria | 2022 |
Stromal cell-derived factor-1 exerts opposing roles through CXCR4 and CXCR7 in angiotensin II-induced adventitial remodeling.
Topics: Adventitia; Angiotensin II; Animals; Benzylamines; Cell Movement; Cell Proliferation; Chemokine CXCL12; Collagen; Cyclams; Disease Models, Animal; Fibroblasts; Fibrosis; Hypertension; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, CXCR; Receptors, CXCR4; Signal Transduction; Wound Healing | 2022 |
Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress.
Topics: Angiotensin II; Animals; Endoplasmic Reticulum Stress; Hemorrhage; Humans; Hypertension; Male; Rats; Rats, Wistar; Renin-Angiotensin System | 2022 |
Zyxin protects from hypertension-induced cardiac dysfunction.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Cardiomegaly; Fibrosis; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Zyxin | 2022 |
Exacerbation of Thrombotic Responses to Silver Nanoparticles in Hypertensive Mouse Model.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Fibrinogen; Hypertension; Male; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Oxidative Stress; Partial Thromboplastin Time; Platelet Aggregation; Polyethylene Glycols; Prothrombin Time; Silver; von Willebrand Factor | 2022 |
Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling.
Topics: Angiotensin II; Animals; Endothelial Cells; Ferroptosis; Fibrosis; Glutathione Peroxidase; Hypertension; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Signal Transduction | 2022 |
Association of Antihypertensives and Cognitive Impairment in Long-Term Care Residents.
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Cognitive Dysfunction; Humans; Hypertension; Long-Term Care; Retrospective Studies | 2022 |
Topics: Angiotensin II; Animals; Carrier Proteins; Fibrosis; Hypertension; Inflammasomes; Inflammation; Mice; MicroRNAs; NLR Family, Pyrin Domain-Containing 3 Protein; Thioredoxins | 2022 |
Diet-induced hypertension in rats is associated with increased renal vasoconstrictor response to angiotensin II after imitated endothelial dysfunction.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Diet; Fructose; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2022 |
Hormone-Dependent Regulation of Renin and Effects on Prorenin Receptor Signaling in the Collecting Duct.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System | 2022 |
MicroRNA-122-5p Aggravates Angiotensin II-Mediated Myocardial Fibrosis and Dysfunction in Hypertensive Rats by Regulating the Elabela/Apelin-APJ and ACE2-GDF15-Porimin Signaling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apelin; Cardiomyopathies; Fibrosis; Growth Differentiation Factor 15; Hypertension; Inflammation; MicroRNAs; Rats | 2022 |
Comparative analysis of hypertensive nephrosclerosis in animal models of hypertension and its relevance to human pathology. Glomerulopathy.
Topics: Angiotensin II; Animals; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Humans; Hypertension; Hypertension, Renal; Male; Nephritis; Nephrosclerosis; Rats; Rats, Inbred SHR; Vasoconstrictor Agents | 2022 |
Endothelial MicroRNA-483-3p Is Hypertension-Protective.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Endothelial Cells; Exosomes; Humans; Hypertension; MicroRNAs; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Telmisartan | 2022 |
Renal artery occlusive disease, renin-angiotensin-aldosterone, inflammation, and refractory arterial hypertension, a half-century's perspective.
Topics: Aldosterone; Angiotensin II; Angiotensins; Blood Pressure; Humans; Hypertension; Inflammation; Renal Artery; Renin; Renin-Angiotensin System | 2022 |
Upregulation of miR-140-5p uncouples mitochondria by targeting Bcl-xL in vascular smooth muscle cells in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Hypertension; Mice; MicroRNAs; Mitochondria; Muscle, Smooth, Vascular; Up-Regulation; Vascular Remodeling | 2022 |
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Hypertension; Ligands; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; NADPH Oxidase 1; NF-E2-Related Factor 2; Peptide Hormones; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptors, Angiotensin; Vascular Remodeling | 2022 |
Experimental uninephrectomy associates with less parasympathetic modulation of heart rate and facilitates sodium-dependent arterial hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Heart Rate; Hypertension; Mice; Sodium; Sodium Chloride; Taurine | 2022 |
Short-Term Pharmacological Induction of Arterial Stiffness and Hypertension with Angiotensin II Does Not Affect Learning and Memory and Cerebral Amyloid Load in Two Murine Models of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloidogenic Proteins; Amyloidosis; Angiotensin II; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypertension; Mice; Vascular Stiffness | 2022 |
Cardiorenal protective effects of sodium-glucose cotransporter 2 inhibition in combination with angiotensin II type 1 receptor blockade in salt-sensitive Dahl rats.
Topics: Angiotensin II; Animals; Blood Pressure; Glucose; Humans; Hypertension; Losartan; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Sodium; Sodium Chloride; Sodium Chloride, Dietary; Sodium-Glucose Transporter 2; Sodium-Hydrogen Exchanger 3 | 2022 |
Changed serum levels of CD62E
Topics: Angiotensin II; Biomarkers; E-Selectin; Glycopeptides; Humans; Hypertension; Sleep Initiation and Maintenance Disorders; Stroke | 2022 |
DP1 (Prostaglandin D
Topics: Angiotensin II; Animals; Cells, Cultured; Fibronectins; Fibrosis; Guanine Nucleotide Exchange Factors; Hypertension; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myofibroblasts; Receptors, Immunologic; Receptors, Prostaglandin; Transcription Factors; Vascular Remodeling | 2022 |
RhoBTB1 reverses established arterial stiffness in angiotensin II-induced hypertension by promoting actin depolymerization.
Topics: Actins; Angiotensin II; Animals; Hypertension; Mice; Muscle, Smooth, Vascular; Vascular Remodeling; Vascular Stiffness | 2022 |
Regulator of G-Protein Signaling 5 Protein Deficiency Differentially Influences Blood Pressure, Vascular and Behavioral Effects in Aged Male Mice.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; GTP-Binding Proteins; Hypertension; Male; Mice; Protein Deficiency; RGS Proteins | 2022 |
Exercise training improves cardiovascular control in sinoaortic denervated SHR by reducing the elevated angiotensin II and augmenting angiotensin-(1-7) availability within autonomic and neuroendocrine PVN nuclei.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Hypertension; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Inbred SHR | 2022 |
Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin-Deficient Mice.
Topics: Angiotensin II; Animals; Aortic Dissection; Aortic Rupture; Disease Models, Animal; Elastin; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteoprotegerin; RANK Ligand | 2022 |
Type 1 Angiotensin Receptors on CD11c-Expressing Cells Protect Against Hypertension by Regulating Dendritic Cell-Mediated T Cell Activation.
Topics: Angiotensin II; Animals; Dendritic Cells; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptors, CCR7; Sodium; T-Lymphocytes | 2022 |
Perivascular Fibrosis Is Mediated by a KLF10-IL-9 Signaling Axis in CD4+ T Cells.
Topics: Angiotensin II; Animals; CD4-Positive T-Lymphocytes; Early Growth Response Transcription Factors; Fibrosis; Humans; Hypertension; Interleukin-9; Kruppel-Like Transcription Factors; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA | 2022 |
TIGAR deficiency sensitizes angiotensin-II-induced renal fibrosis and glomerular injury.
Topics: Angiotensin II; Animals; Apoptosis Regulatory Proteins; Blood Pressure; Female; Fibrosis; Glycolysis; Humans; Hypertension; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoric Monoester Hydrolases | 2022 |
Naoxintong Capsule Activates the Nrf2/HO-1 Signaling Pathway and Suppresses the p38α Signaling Pathway Via Estrogen Receptors to Ameliorate Heart Remodeling in Female Mice With Postmenopausal Hypertension.
Topics: Angiotensin II; Animals; Body Weight; Drugs, Chinese Herbal; Female; Fibrosis; Heme Oxygenase-1; Hypertension; Membrane Proteins; Mice; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Postmenopause; Receptors, Estrogen; Signal Transduction; Ventricular Remodeling | 2022 |
Interleukin 10 Attenuates Angiotensin II-Induced Aortic Remodelling by Inhibiting Oxidative Stress-Induced Activation of the Vascular p38 and NF-
Topics: Angiotensin II; Animals; Cells, Cultured; Fibrosis; Humans; Hypertension; Interleukin-10; Matrix Metalloproteinase 2; Mice; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Signal Transduction | 2022 |
Soluble ACE2 and angiotensin II levels are modulated in hypertensive COVID-19 patients treated with different antihypertension drugs.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; COVID-19 Drug Treatment; Humans; Hypertension | 2022 |
Interleukin-22 exacerbates angiotensin II-induced hypertensive renal injury.
Topics: Angiotensin II; Animals; Fibrosis; Humans; Hypertension; Inflammation; Interleukin-22; Interleukins; Kidney; Kidney Diseases; Mice; Mice, Inbred C57BL | 2022 |
Effect of Yiqi Huayu Pinggan Zishen Formula Combined with Valsartan in the Treatment of Hypertension and Its Effect on MMP-9, Ang II, and MCP-1.
Topics: Angiotensin II; Antihypertensive Agents; Chemokine CCL2; Drugs, Chinese Herbal; Humans; Hypertension; Matrix Metalloproteinase 9; Syndrome; Valsartan | 2022 |
Interleukin 17A infusion has no acute or long-term hypertensive action in conscious unrestrained male mice.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Inflammation; Interleukin-17; Interleukin-6; Male; Mice | 2022 |
Renin-Angiotensin System Pathway Therapeutics Associated With Improved Outcomes in Males Hospitalized With COVID-19.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Canada; COVID-19 Drug Treatment; Female; Humans; Hypertension; Male; Prospective Studies; Renin-Angiotensin System; Sex Characteristics | 2022 |
NLRP3 inflammasome contributes to endothelial dysfunction in angiotensin II-induced hypertension in mice.
Topics: Angiotensin II; Animals; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Inflammasomes; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; NLR Family, Pyrin Domain-Containing 3 Protein | 2022 |
Mediterranean G6PD variant rats are protected from Angiotensin II-induced hypertension and kidney damage, but not from inflammation and arterial stiffness.
Topics: Actins; Angiotensin II; Animals; Glucosephosphate Dehydrogenase Deficiency; Humans; Hypertension; Inflammation; Inositol; Interleukin-6; Kidney; Myosin Heavy Chains; Phosphates; Rats; Superoxides; Vascular Stiffness | 2022 |
Suppression of angiotensin II-activated NOX4/NADPH oxidase and mitochondrial dysfunction by preserving glucagon-like peptide-1 attenuates myocardial fibrosis and hypertension.
Topics: Angiotensin II; Animals; Cardiomyopathies; Fibrosis; Glucagon-Like Peptide 1; Hypertension; Linagliptin; Liraglutide; Mitochondria; NADPH Oxidase 4; Rats; Rats, Sprague-Dawley | 2022 |
Corynoline protects ang II-induced hypertensive heart failure by increasing PPARα and Inhibiting NF-κB pathway.
Topics: Angiotensin II; Animals; Berberine Alkaloids; Fibrosis; Heart Failure; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; NF-kappa B; PPAR alpha; RNA | 2022 |
Plasmatic renin-angiotensin system in normotensive and hypertensive patients hospitalized with COVID-19.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2022 |
Reducing Proteoglycan Synthesis and NOX Activity by ROCK Inhibitors: Therapeutic Targets in Atherosclerosis.
Topics: Angiotensin II; Atherosclerosis; Endothelin-1; Humans; Hypertension; Protein Serine-Threonine Kinases; Proteoglycans; Receptors, G-Protein-Coupled; rho-Associated Kinases; Serine | 2022 |
Angiotensin II-induced endothelial dysfunction: Impact of sex, genetic background, and rho kinase.
Topics: Angiotensin II; Animals; Endothelial Cells; Endothelium, Vascular; Female; Genetic Background; Hypertension; Male; Mice; Mice, Inbred C57BL; rho-Associated Kinases | 2022 |
SIRT1 exerts anti-hypertensive effect via FOXO1 activation in the rostral ventrolateral medulla.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Forkhead Box Protein O1; Heart Rate; Hypertension; Nerve Tissue Proteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Sirtuin 1; Superoxide Dismutase; Superoxide Dismutase-1 | 2022 |
G-protein-coupled receptor kinase 4 causes renal angiotensin II type 2 receptor dysfunction by increasing its phosphorylation.
Topics: Adenosine Triphosphatases; Angiotensin II; Animals; G-Protein-Coupled Receptor Kinase 4; Hypertension; Mice; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2022 |
Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Hypertension; Kidney; Mice; Mice, Inbred C57BL; Renal Artery; Sympathectomy | 2022 |
The protective effects of hyperoside on Ang II-mediated apoptosis of bEnd.3 cells and injury of blood-brain barrier model in vitro.
Topics: Angiotensin II; Animals; Apoptosis; Blood-Brain Barrier; Humans; Hypertension; Mice; Quercetin | 2022 |
Low-dose rapamycin prevents Ang-II-induced toxicity in Leydig cells and testicular dysfunction in hypertensive SHR model.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Female; Humans; Hydroxysteroid Dehydrogenases; Hypertension; Leydig Cells; Male; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR; Sirolimus; Superoxides | 2022 |
Topics: Adult; Angiotensin II; Animals; Athletic Performance; Blood Pressure; COVID-19; Diabetes Mellitus; Humans; Hypertension; Isoproterenol; Male; Muscle Fatigue; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptors, Adrenergic; Running; Soccer; Streptozocin; Wine; Young Adult | 2022 |
Restoration of Cullin3 gene expression enhances the improved effects of sonic hedgehog signaling activation for hypertension and attenuates the dysfunction of vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Cullin Proteins; Gene Expression; Hedgehog Proteins; Hypertension; Mice; Muscle, Smooth, Vascular; Reactive Oxygen Species; Signal Transduction | 2022 |
PKN2 deficiency leads both to prenatal 'congenital' cardiomyopathy and defective angiotensin II stress responses.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiomyopathies; Female; Hypertension; Mice; Mice, Knockout; Myocardium; Myocytes, Cardiac; Pregnancy; Protein Kinase C | 2022 |
Exercise-derived peptide protects against pathological cardiac remodeling.
Topics: Angiotensin II; Animals; China; Extracellular Matrix Proteins; Heart; Heart Failure; Humans; Hypertension; Mice; Myocytes, Cardiac; Ventricular Remodeling | 2022 |
Estradiol Supplement or Induced Hypertension May Attenuate the Angiotensin II Type 1 Receptor Antagonist-Promoted Renal Blood Flow Response to Graded Angiotensin II Administration in Ovariectomized Rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Estradiol; Female; Hypertension; Losartan; Rats; Receptor, Angiotensin, Type 1; Renal Circulation | 2022 |
Ang II (Angiotensin II)-Induced FGFR1 (Fibroblast Growth Factor Receptor 1) Activation in Tubular Epithelial Cells Promotes Hypertensive Kidney Fibrosis and Injury.
Topics: Angiotensin II; Animals; Epithelial Cells; Fibrosis; Humans; Hypertension; Hypertension, Renal; Kidney; Mice; Mice, Inbred C57BL; Nephritis; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Angiotensin | 2022 |
Conventional Vasopressor and Vasopressor-Sparing Strategies to Counteract the Blood Pressure-Lowering Effect of Small Interfering RNA Targeting Angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Fludrocortisone; Hypertension; Mice; Midodrine; Norepinephrine; Rats; Renin; Renin-Angiotensin System; RNA, Small Interfering; Vasoconstrictor Agents | 2022 |
Immunosuppression by Mycophenolate Mofetil Mitigates Intrarenal Angiotensinogen Augmentation in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension; Immunosuppression Therapy; Kidney; Kidney Diseases; Mycophenolic Acid; Proteinuria; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2022 |
Of Mouse and Man: Cross-Species Characterization of Hypertensive Cardiac Remodeling.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Heart; Humans; Hypertension; Mice; Myocardium; Myocytes, Cardiac; Ventricular Remodeling | 2022 |
miR-21 upregulation exacerbates pressure overload-induced cardiac hypertrophy in aged hearts.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Humans; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Myocytes, Cardiac; Up-Regulation; Ventricular Remodeling | 2022 |
Hinokitiol produces vasodilation in aortae from normal and angiotensin II- induced hypertensive rats via endothelial-dependent and independent pathways.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Angiotensin II; Animals; Calcium Channels, L-Type; Endothelium, Vascular; Guanylate Cyclase; Hypertension; Nitric Oxide Synthase; Phenylephrine; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Rats; Vasodilation | 2022 |
Dahl salt-resistant rats are protected against angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney; Rats; Rats, Inbred Dahl; Sodium Chloride; Sodium Chloride, Dietary; Vasoconstrictor Agents | 2022 |
Bovine Bone Gelatin-Derived Peptides: Food Processing Characteristics and Evaluation of Antihypertensive and Antihyperlipidemic Activities.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cattle; Cholesterol; Food Handling; Gelatin; Hypertension; Hypolipidemic Agents; Peptides; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1 | 2022 |
Empagliflozin prevents angiotensin II-induced hypertension related micro and macrovascular endothelial cell activation and diastolic dysfunction in rats despite persistent hypertension: Role of endothelial SGLT1 and 2.
Topics: Angiotensin II; Animals; Benzhydryl Compounds; Blood Pressure; Collagen; Endothelial Cells; Fibrosis; Glucosides; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Vascular Cell Adhesion Molecule-1 | 2022 |
Effect of Angiotensin receptor blockade on Plasma Osmolality and Neurohumoral Responses to High Environmental Temperature in Rats Fed a High Salt Diet.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diet; Hypertension; Male; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sodium Chloride; Sodium Chloride, Dietary; Telmisartan; Temperature | 2021 |
Swimming Exercise Alleviates Endothelial Mitochondrial Fragmentation via Inhibiting Dynamin-Related Protein-1 to Improve Vascular Function in Hypertension.
Topics: Angiotensin II; Animals; Dynamins; Endothelial Cells; Endothelium, Vascular; Humans; Hypertension; Mice; Mitochondrial Dynamics; Rats; Swimming | 2022 |
Broad-acting therapeutic effects of miR-29b-chitosan on hypertension and diabetic complications.
Topics: Angiotensin II; Animals; Chitosan; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Fibrosis; Humans; Hypertension; Mice; Mice, Inbred Strains; Mice, Knockout, ApoE; MicroRNAs; Thiolester Hydrolases | 2022 |
Effects of 3-methyladenine, an autophagy inhibitor, on the elevated blood pressure and arterial dysfunction of angiotensin II-induced hypertensive mice.
Topics: Adenine; Angiotensin II; Animals; Autophagy; Beclin-1; Blood Pressure; Endothelium, Vascular; Hypertension; Mesenteric Arteries; Mice; Nitric Oxide; Vasodilation | 2022 |
Diacerein alleviates Ang II-induced cardiac inflammation and remodeling by inhibiting the MAPKs/c-Myc pathway.
Topics: Angiotensin II; Animals; Anthraquinones; Cardiomegaly; Cardiomyopathies; Fibrosis; Heart Failure; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; RNA; Ventricular Remodeling | 2022 |
Renomedullary exosomes produce antihypertensive effects in reversible two-kidney one-clip renovascular hypertensive mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuretics; Exosomes; Hypertension; Kidney; Lipids; Male; Mice; Natriuretic Agents; Sirolimus | 2022 |
Targeting the blood-brain barrier disruption in hypertension by ALK5/TGF-Β type I receptor inhibitor SB-431542 and dynamin inhibitor dynasore.
Topics: Albumins; Angiotensin II; Animals; Benzamides; Blood-Brain Barrier; Claudin-5; Dioxoles; Dynamins; Hydrazones; Hypertension; Mice; Receptor, Transforming Growth Factor-beta Type I; Transforming Growth Factor beta | 2022 |
Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy.
Topics: Angiotensin II; Animals; Autophagy; DNA, Mitochondrial; Heart Diseases; Heart Injuries; Hypertension; Mice; Microglia; Nucleotidyltransferases; Paraventricular Hypothalamic Nucleus; Sirolimus | 2022 |
Qingda granule alleviate angiotensin ⅱ-induced hypertensive renal injury by suppressing oxidative stress and inflammation through NOX1 and NF-κB pathways.
Topics: Angiotensin II; Animals; Drugs, Chinese Herbal; Hypertension; Inflammation; Kidney; Mice; NF-kappa B; Nitrogen Oxides; Oxidative Stress | 2022 |
Angiotensin II prompts heart cell apoptosis via AT1 receptor-augmented phosphatase and tensin homolog and miR-320-3p functions to enhance suppression of the IGF1R-PI3K-AKT survival pathway.
Topics: Angiotensin II; Animals; Apoptosis; Hypertension; MicroRNAs; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Tensins | 2022 |
Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Humans; Hypertension; Kidney Diseases; Liver; Rats; Renin; Renin-Angiotensin System; RNA, Small Interfering; Valsartan | 2023 |
Inhibition of MyD88 attenuates angiotensin II-induced hypertensive kidney disease via regulating renal inflammation.
Topics: Angiotensin II; Animals; Cytokines; Fibrosis; Hypertension; Hypertension, Renal; Inflammation; Kidney; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; NF-kappa B; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4 | 2022 |
Activation of the Mas receptors by AVE0991 and MrgD receptor using alamandine to limit the deleterious effects of Ang II-induced hypertension.
Topics: Angiotensin II; Animals; Hypertension; Matrix Metalloproteinase 2; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2023 |
Renin-a in the Subfornical Organ Plays a Critical Role in the Maintenance of Salt-Sensitive Hypertension.
Topics: Angiotensin II; Animals; Cholinergic Agents; Desoxycorticosterone Acetate; Hypertension; Mice; NADPH Oxidase 2; Renin; RNA, Messenger; Sodium Chloride; Sodium, Dietary; Subfornical Organ; Tyrosine 3-Monooxygenase | 2022 |
Functional Significance of Angiotensin Receptor Type 2 in the Neuroplasticity of Autonomic Ganglia in (mRen2)27 Transgenic Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Ganglia, Autonomic; Humans; Hypertension; NADPH Oxidase 4; Neuronal Plasticity; Rats; Rats, Transgenic; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; RNA, Messenger | 2023 |
Estrogen receptor beta activity contributes to both tumor necrosis factor alpha expression in the hypothalamic paraventricular nucleus and the resistance to hypertension following angiotensin II in female mice.
Topics: Angiotensin II; Animals; Blood Pressure; Estrogen Receptor beta; Female; Hypertension; Male; Mice; Neurons; Paraventricular Hypothalamic Nucleus; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha | 2022 |
Oviductal Glycoprotein 1 Promotes Hypertension by Inducing Vascular Remodeling Through an Interaction With MYH9.
Topics: Angiotensin II; Animals; Cytoskeletal Proteins; Glycoproteins; Hypertension; Inflammation; Mice; Mice, Knockout; Mice, Transgenic; Myosin Heavy Chains; Vascular Remodeling | 2022 |
Sclareol attenuates angiotensin II-induced cardiac remodeling and inflammation via inhibiting MAPK signaling.
Topics: Angiotensin II; Animals; Fibrosis; Heart Failure; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardium; Myocytes, Cardiac; Ventricular Remodeling | 2023 |
Green tea could improve elderly hypertension by modulating arterial stiffness, the activity of the renin/angiotensin/aldosterone axis, and the sodium-potassium pumps in old male rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Hypertension; Lipids; Male; Nitric Oxide; Rats; Renin; Sodium Chloride; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Tea; Vascular Stiffness | 2022 |
Increased production of inflammatory cytokines and activation of microglia in the fetal brain of preeclamptic mice induced by angiotensin II.
Topics: Angiotensin II; Animals; Brain; Cytokines; Female; Humans; Hypertension; Interleukin-6; Mice; Microglia; Pre-Eclampsia; Pregnancy | 2022 |
The intrarenal blood pressure modulation system is differentially altered after renal denervation guided by different intensities of blood pressure responses.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Dogs; Hypertension; Kidney; Renin-Angiotensin System; Sodium; Sympathectomy | 2023 |
Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Endothelin-1; Endothelins; Fistula; Heart Failure; Hypertension; Rats; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptor, Endothelin A | 2023 |
Angiotensin II differentially affects hippocampal glial inflammatory markers in young adult male and female mice.
Topics: Angiotensin II; Animals; Astrocytes; Biomarkers; Calcium; Calcium-Binding Proteins; Cytokines; Female; Glial Fibrillary Acidic Protein; Hippocampus; Hypertension; Male; Mice | 2022 |
Restoration of Mitochondrial Function Is Essential in the Endothelium-Dependent Vasodilation Induced by Acacetin in Hypertensive Rats.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Blood Pressure; Endothelium, Vascular; Flavones; Hypertension; Hypotension; Mitochondria; Mitochondrial Permeability Transition Pore; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptidyl-Prolyl Isomerase F; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Vasodilation | 2022 |
Plasticity of cerebral microvascular structure and mechanics during hypertension and following recovery of arterial pressure.
Topics: Angiotensin II; Animals; Arterial Pressure; Arterioles; Blood Pressure; Hypertension; Male; Mice; Mice, Inbred C57BL | 2022 |
Epigallocatechin gallate (EGCG) alleviates vascular dysfunction in angiotensin II-infused hypertensive mice by modulating oxidative stress and eNOS.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cyclic GMP; Endothelium, Vascular; Guanosine Monophosphate; Hypertension; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Reactive Oxygen Species | 2022 |
Mutagenesis of the cleavage site of (pro)renin receptor abrogates aldosterone-salt-induced hypertension and renal injury in mice.
Topics: Aldosterone; Angiotensin II; Animals; Hypertension; Kidney; Mice; Mineralocorticoids; Mutagenesis; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary | 2023 |
Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.
Topics: Angiotensin II; Animals; Ferroptosis; Fibrosis; Hypertension; Kidney; Kidney Diseases; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Sirtuins | 2022 |
Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Fibrosis; Hypertension; Mice; Mice, Inbred C57BL | 2023 |
Qian Yang Yu Yin granule improves hypertensive renal damage: A potential role for TRPC6-CaMKKβ-AMPK-mTOR-mediated autophagy.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Autophagy; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Hypertension; Podocytes; Rats; TOR Serine-Threonine Kinases; TRPC Cation Channels; TRPC6 Cation Channel | 2023 |
Increased Arterial Responsiveness to Angiotensin II in Mice Conceived by Assisted Reproductive Technologies.
Topics: Angiotensin II; Animals; Hypertension; Mice; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reproductive Techniques, Assisted; Vasoconstrictor Agents | 2022 |
Phospholipase Cε insufficiency causes ascending aortic aneurysm and dissection.
Topics: Aneurysm, Ascending Aorta; Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic Valve Insufficiency; Death, Sudden; Humans; Hypertension; Mice; Mice, Inbred C57BL | 2022 |
Integrin CD11b Contributes to Hypertension and Vascular Dysfunction Through Mediating Macrophage Adhesion and Migration.
Topics: Angiotensin II; Animals; Hypertension; Integrins; Macrophages; Mice | 2023 |
Angiotensin-(1-9) prevents angiotensin II-induced endothelial apoptosis through CNPY2/PERK pathway.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Apoptosis; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Mice; Signal Transduction | 2023 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotension; Male; Rats; Rats, Inbred Dahl; Rats, Transgenic; Renin; Sodium Chloride; Sodium Chloride, Dietary; Sympathetic Nervous System | 2022 |
Endoplasmic Reticulum Chemical Chaperone 3-Hydroxy-2-Naphthoic Acid Reduces Angiotensin II-Induced Vascular Remodeling and Hypertension In Vivo and Protein Synthesis In Vitro.
Topics: Angiotensin II; Animals; Endoplasmic Reticulum; Hydroxy Acids; Hypertension; Mice; Vascular Remodeling | 2022 |
Minocycline and Pyrrolidine Dithiocarbamate Attenuate Hypertension via Suppressing Activation of Microglia in the Hypothalamic Paraventricular Nucleus.
Topics: Angiotensin II; Animals; Cytokines; Hypertension; Male; Microglia; Minocycline; Neurotransmitter Agents; NF-kappa B; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2023 |
Effects of intrarenal angiotensin 1-7 infusion on renal haemodynamic and excretory function in anaesthetised two-kidney one-clip and deoxycorticosterone acetate-salt hypertensive rats.
Topics: Acetates; Angiotensin II; Animals; Desoxycorticosterone Acetate; Hemodynamics; Hypertension; Kidney; Rats | 2023 |
Maternal exercise upregulates the DNA methylation of Agtr1a to enhance vascular function in offspring of hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; DNA Methylation; Female; Hypertension; Male; Pregnancy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1 | 2023 |
Andrographolide improves the dysfunction of endothelial progenitor cells from angiotensin II-induced hypertensive mice through SIRT1 signaling.
Topics: Angiotensin II; Animals; Cells, Cultured; Endothelial Progenitor Cells; Hypertension; Mice; Sirtuin 1 | 2023 |
Neurons of the median preoptic nucleus contribute to chronic angiotensin II-salt induced hypertension in the rat.
Topics: Angiotensin II; Animals; Hypertension; Ibotenic Acid; Male; Neurons; Preoptic Area; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2022 |
Soluble ACE2 Is Filtered into the Urine.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Hypertension; Kidney; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2022 |
Association of New Use of Antihypertensives That Stimulate vs Inhibit Type 2 and 4 Angiotensin II Receptors With Dementia Among Medicare Beneficiaries.
Topics: Aged; Alzheimer Disease; Angiotensin II; Antihypertensive Agents; Cohort Studies; Female; Humans; Hypertension; Male; Medicare; United States | 2023 |
Angiotensin II Type 1A Receptor Expressed in Smooth Muscle Cells is Required for Hypertensive Vascular Remodeling in Mice Infused With Angiotensin II.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibrosis; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1; Vascular Remodeling | 2023 |
YAP-galectin-3 signaling mediates endothelial dysfunction in angiotensin II-induced hypertension in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelium, Vascular; Galectin 3; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Mice; Signal Transduction | 2023 |
Estimation of Central Systolic Blood Pressure from Peripheral Pressure Waves using a Novel Second Systolic Pressure-Based Method in Normal and Heritable Hypercholesterolemic Rabbits.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blood Pressure Determination; Hypertension; Rabbits | 2023 |
Analysis of Mechanisms for Increased Blood Pressure Variability in Rats Continuously Infused with Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Rats; Rats, Wistar | 2023 |
MiR-3646 accelerates inflammatory response of Ang II-induced hVSMCs via CYP2J2/EETs axis in hypertension model.
Topics: Angiotensin II; Animals; Cells, Cultured; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Eicosanoids; Humans; Hypertension; Mice; MicroRNAs | 2023 |
The renin-angiotensin-aldosterone system: a new look at an old system.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Renin-Angiotensin System | 2023 |
Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; beta-Arrestin 2; Humans; Hypertension; Peptides; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System | 2023 |
Dectin-1 Acts as a Non-Classical Receptor of Ang II to Induce Cardiac Remodeling.
Topics: Angiotensin II; Animals; Fibrosis; Heart Failure; Hypertension; Lectins, C-Type; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; NF-kappa B; Ventricular Remodeling | 2023 |
Anti-Fibrotic Potential of Angiotensin (1-7) in Hemodynamically Overloaded Rat Heart.
Topics: Angiotensin II; Animals; Connexin 43; Fibrosis; Heart; Heart Failure; Hypertension; Male; Rats; Rats, Transgenic | 2023 |
Neurovascular Coupling in Hypertension Is Impaired by IL-17A through Oxidative Stress.
Topics: Alzheimer Disease; Angiotensin II; Humans; Hypertension; Interleukin-17; NADPH Oxidases; Neurovascular Coupling; Oxidative Stress; Stroke; Superoxides | 2023 |
Serum exosomes derived from spontaneously hypertensive rats induce cardiac hypertrophy in vitro and in vivo by increasing autocrine release of angiotensin II in cardiomyocytes.
Topics: Angiotensin II; Animals; Cardiomegaly; Exosomes; Hypertension; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System | 2023 |
Paeonol improves renal and vascular angiotensin II type 1 receptor function via inhibiting oxidative stress in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Kidney; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renin; Vasoconstrictor Agents | 2023 |
Relationship between Angiotensin II, Vascular Endothelial Growth Factor, and Arteriosclerosis Obliterans.
Topics: Angiotensin II; Arteriosclerosis Obliterans; Female; Humans; Hypertension; Male; Peptide Hormones; Vascular Endothelial Growth Factor A | 2023 |
Chronic administration of catalase inhibitor attenuates hypertension in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Catalase; Hydrogen Peroxide; Hypertension; Hypertension, Renovascular; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2023 |
Expression of Trpa1 and Trpv1 Genes in the Hypothalamus and Blood Pressure in Normotensive and Hypertensive Rats. Effect of Losartan and Captopril.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension; Hypothalamus; Losartan; Rats; TRPA1 Cation Channel; TRPV Cation Channels | 2023 |
Female mice are protected from impaired parenchymal arteriolar TRPV4 function and impaired cognition in hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cognition; Cognitive Dysfunction; Dementia; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; TRPV Cation Channels | 2023 |
Waterpipe smoke inhalation potentiates cardiac oxidative stress, inflammation, mitochondrial dysfunction, apoptosis and autophagy in experimental hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Hypertension; Inflammation; Mice; Mitochondria; Myocytes, Cardiac; Oxidative Stress; Water Pipe Smoking | 2023 |
Effect of bempedoic acid on angiotensin-II induced hypertension and vascular tissue remodelling in renal hypertensive rats through AMPK multiple signalling pathways modulation.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension; Male; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2023 |
Oral administration of the herbal oligonucleotide XKC-sRNA-h3 prevents angiotensin II-induced hypertension in mice.
Topics: Administration, Oral; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hypertension; Mice | 2023 |
The intrarenal renin-angiotensin system in hypertension: insights from mathematical modelling.
Topics: Angiotensin II; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2023 |
Reference intervals for LC-MS /MS measurements of plasma renin activity, aldosterone, angiotensin II, and 24-hour urinary aldosterone in Northern Chinese Han population.
Topics: Aldosterone; Angiotensin II; Chromatography, Liquid; East Asian People; Healthy Volunteers; Humans; Hyperaldosteronism; Hypertension; Peptide Hormones; Reference Values; Renin; Renin-Angiotensin System; Tandem Mass Spectrometry | 2023 |
Ovariectomy Via 12/15-lipoxygenase Augments Angiotensin II-Induced Hypertension and Its Pathogenesis in Female Mice.
Topics: Angiotensin II; Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Blood Pressure; Estradiol; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Mice; Mice, Knockout; Ovariectomy; Reactive Oxygen Species | 2023 |
USP25 inhibits renal fibrosis by regulating TGFβ-SMAD signaling pathway in Ang II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Deubiquitinating Enzymes; Fibrosis; Humans; Hypertension; Hypertension, Renal; Mice; Signal Transduction; Transforming Growth Factor beta; Ubiquitin Thiolesterase | 2023 |
Complement component C3 as a new target to lower albuminuria in hypertensive kidney disease.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Hypertension; Hypertension, Renal; Kidney; Mice; RNA, Small Interfering | 2023 |
Improvement in Blood Pressure After Intermittent Fasting in Hipertension: Could Renin-Angiotensin System and Autonomic Nervous System Have a Role?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Autonomic Nervous System; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Intermittent Fasting; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 2023 |
The mechanism underlying fluoride-induced low-renin hypertension is related to an imbalance in the circulatory and local renin-angiotensin systems.
Topics: Angiotensin II; Fluorides; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2023 |
Ghrelin improves endothelial function and reduces blood pressure in Ang II-induced hypertensive mice: Role of AMPK.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Blood Pressure; Endothelium, Vascular; Ghrelin; Hypertension; Mice; Oxidative Stress | 2023 |
FGFR2 modulates the Akt/Nrf2/ARE signaling pathway to improve angiotensin II-induced hypertension-related endothelial dysfunction.
Topics: Angiotensin II; Antioxidant Response Elements; Apoptosis; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptor, Fibroblast Growth Factor, Type 2; Signal Transduction | 2023 |
Nedd4-2 up-regulation is associated with ACE2 ubiquitination in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Hypertension; Mice; Peptidyl-Dipeptidase A; Ubiquitin-Protein Ligases; Ubiquitination; Up-Regulation | 2023 |
Design, synthesis and biological evaluation of novel indole-3-carboxylic acid derivatives with antihypertensive activity.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Hypertension; Losartan; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles | 2023 |
A novel role for the histone modifier PRDM6 and an opportunity to understand hypertension.
Topics: Angiotensin II; Histones; Humans; Hypertension; Muscle, Smooth, Vascular; Renin; Renin-Angiotensin System | 2023 |
Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet.
Topics: Angiotensin II; Angiotensinogen; Animals; Diet, High-Fat; Hypertension; Male; Mice; Mice, Inbred C57BL; Obesity; Proto-Oncogene Proteins c-myc; Signal Transduction | 2023 |
SARS-CoV-2 Spike Protein S1 Exposure Increases Susceptibility to Angiotensin II-Induced Hypertension in Rats by Promoting Central Neuroinflammation and Oxidative Stress.
Topics: Angiotensin II; Animals; Blood Pressure; COVID-19; Cytokines; Humans; Hypertension; Neuroinflammatory Diseases; NF-E2-Related Factor 2; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; RNA, Messenger; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2023 |
Ginsenoside Rg5 alleviates Ang II-induced cardiac inflammation and remodeling by inhibiting the JNK/AP-1 pathway.
Topics: Angiotensin II; Animals; Arrhythmias, Cardiac; Heart Failure; Hypertension; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Transcription Factor AP-1 | 2023 |
Vascular smooth muscle cells specific deletion of angiopoietin-like protein 8 prevents angiotensin II-promoted hypertension and cardiovascular hypertrophy.
Topics: Angiopoietin-Like Protein 8; Angiotensin II; Animals; Hypertension; Hypertrophy; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR | 2023 |
Co-administration of angiotensin II and simvastatin triggers kidney injury upon heme oxygenase-1 deficiency.
Topics: Angiotensin II; Animals; Glutathione; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hypertension; Iron; Kidney; Mice; Mucin-1; Simvastatin | 2023 |
Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Hypertension; Mice; Mice, Inbred C57BL; Prunus; Prunus domestica; Vascular Remodeling | 2023 |
Prolylcarboxypeptidase Alleviates Hypertensive Cardiac Remodeling by Regulating Myocardial Tissue Angiotensin II.
Topics: Angiotensin II; Animals; Fibrosis; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Ventricular Remodeling | 2023 |
Persistent non-homeostatic remodeling of aortic collagen following a brief episode of hypertension: A computational study.
Topics: Angiotensin II; Animals; Aorta; Aorta, Thoracic; Collagen; Homeostasis; Hypertension; Mice | 2023 |
Durative sleep fragmentation with or without hypertension suppress rapid eye movement sleep and generate cerebrovascular dysfunction.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Dementia, Vascular; Hypertension; Mice; Sleep Deprivation; Sleep, REM; Vascular Remodeling | 2023 |
Unveiling Angiotensin II and Losartan-Induced Gene Regulatory Networks Using Human Urine-Derived Podocytes.
Topics: Angiotensin II; Gene Regulatory Networks; Humans; Hypertension; Losartan; Podocytes; Receptor, Angiotensin, Type 1 | 2023 |
Cardioprotective Effects of Sodium Glucose Cotransporter 2 Inhibition in Angiotensin II-Dependent Hypertension Are Mediated by the Local Reduction of Sympathetic Activity and Inflammation.
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Cardiomegaly; Fibrosis; Hypertension; Inflammation; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Tyrosine 3-Monooxygenase | 2023 |
Browning of perivascular adipose tissue prevents vascular dysfunction and reduces hypertension in angiotensin II-infused mice.
Topics: Adipose Tissue; Angiotensin II; Animals; Blood Pressure; Hypertension; Mice; Vascular Resistance | 2023 |
Serum uric acid: a futile bystander in endothelial function?
Topics: Adult; Allantoin; Angiotensin II; Blood Pressure; Humans; Hypertension; Lysine; Male; Microcirculation; Pulse Wave Analysis; Uric Acid; Vascular Stiffness | 2023 |
Targeting the adenosine monophosphate-activated protein kinase signalling pathway by bempedoic acid attenuates Angiotensin II-induced cardiac remodelling in renovascular hypertension in rats.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Captopril; Hypertension; Hypertension, Renovascular; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Ventricular Remodeling | 2023 |
Oat Beta-Glucan Alone and in Combination with Hydrochlorothiazide Lowers High Blood Pressure in Male but Not Female Spontaneously Hypertensive Rats.
Topics: Angiotensin II; Animals; beta-Glucans; Blood Pressure; Female; Heart Diseases; Hydrochlorothiazide; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2023 |
Emerging evidence for a cardiovascular protective effect of concentrated Japanese plum juice.
Topics: Angiotensin II; Animals; Hypertension; Mice; Peptide Hormones; Prunus; Prunus domestica; Vascular Remodeling | 2023 |
Inhibition of miR-25 Ameliorates Cardiac Dysfunction and Fibrosis by Restoring Krüppel-like Factor 4 Expression.
Topics: Angiotensin II; Animals; Calcium; Cardiomegaly; Cardiomyopathies; Fibrosis; Hypertension; Kruppel-Like Factor 4; Mice; Mice, Inbred C57BL; MicroRNAs; Myocytes, Cardiac | 2023 |
Expression of LRG-1 in mice with hypertensive renal damage and its significance.
Topics: Angiotensin II; Animals; Collagen Type I; Creatinine; Fibronectins; Hypertension; Irbesartan; Kidney; Mice; Mice, Inbred C57BL | 2023 |
Impaired renal autoregulation and pressure-natriuresis: any role in the development of heart failure in normotensive and angiotensin II-dependent hypertensive rats?
Topics: Angiotensin II; Animals; Blood Pressure; Heart Failure; Homeostasis; Hypertension; Kidney; Natriuresis; Rats; Rats, Transgenic; Renal Circulation; Sodium | 2023 |
Vasoactive mediators of hypertension in obesity.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Cross-Sectional Studies; Humans; Hypertension; Male; Neprilysin; Obesity, Morbid; Renin; Renin-Angiotensin System; Vasoconstrictor Agents; Vasodilator Agents | 2023 |
GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; G-Protein-Coupled Receptor Kinase 2; Hypertension; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Uridine Triphosphate; Vasoconstrictor Agents | 2023 |
Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Female; Humans; Hypertension; Lacticaseibacillus paracasei; Male; Peptidyl-Dipeptidase A; Rats | 2023 |
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) drives angiotensin II-induced vascular remodeling through regulating mitochondrial fragmentation.
Topics: Angiotensin II; Animals; Catalytic Domain; DNA; DNA-Activated Protein Kinase; Humans; Hypertension; Mice; Myocytes, Smooth Muscle; Rats; Vascular Remodeling | 2023 |
P2RX7 gene knockout or antagonism reduces angiotensin II-induced hypertension, vascular injury and immune cell activation.
Topics: Angiotensin II; Animals; Gene Knockout Techniques; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Purinergic P2X7; T-Lymphocytes; Vascular System Injuries | 2023 |
Resolvin E1/ChemR23 Protects Against Hypertension and Vascular Remodeling in Angiotensin II-Induced Hypertensive Mice.
Topics: Angiotensin II; Animals; Chemokines; Eicosapentaenoic Acid; Humans; Hypertension; Inflammation; Intercellular Signaling Peptides and Proteins; Mice; NF-E2-Related Factor 2; NF-kappa B; Peptide Hormones; Vascular Remodeling | 2023 |
Decreased sympathetic nerve activity in young hypertensive rats reared by normotensive mothers.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Female; Humans; Hypertension; Kidney; Male; Mothers; Rats; Rats, Sprague-Dawley; Renin | 2023 |
20(S)-ginsenoside Rh2 inhibits angiotensin-2 mediated cardiac remodeling and inflammation associated with suppression of the JNK/AP-1 pathway.
Topics: Angiotensin II; Animals; Heart Failure; Hypertension; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Transcription Factor AP-1; Ventricular Remodeling | 2023 |
Aqueous Fraction from
Topics: Angiotensin II; Animals; Blood Pressure; Cucumis sativus; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Peptide Hormones; Plant Components, Aerial; Proto-Oncogene Proteins c-akt; Vascular Remodeling | 2023 |
Chemical Stimulation of Renal Tissue Induces Sympathetic Activation and a Pressor Response via the Paraventricular Nucleus in Rats.
Topics: Angiotensin II; Animals; Arterial Pressure; Blood Pressure; Bradykinin; Capsaicin; Heart Rate; Hypertension; Kidney; Male; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reflex; Stimulation, Chemical; Sympathetic Nervous System | 2020 |
Reduction of glyoxalase 1 (GLO1) aggravates cerebrovascular remodeling via promoting the proliferation of basilar smooth muscle cells in hypertension.
Topics: Angiotensin II; Animals; Brain; Cell Proliferation; Cells, Cultured; Hypertension; Lactoylglutathione Lyase; Male; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Rats, Sprague-Dawley; Vascular Remodeling | 2019 |
TRPV1 (Transient Receptor Potential Vanilloid 1) Cardiac Spinal Afferents Contribute to Hypertension in Spontaneous Hypertensive Rat.
Topics: Angiotensin II; Animals; Arterial Pressure; Blood Pressure; Diterpenes; Ganglia, Spinal; Heart; Heart Rate; Hypertension; Male; Neurotoxins; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System; TRPV Cation Channels | 2019 |
Augmenting Renal Lymphatic Density Prevents Angiotensin II-Induced Hypertension in Male and Female Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Hypertension; Kidney; Lymphangiogenesis; Lymphatic Vessels; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Mice, Transgenic; Spleen; Vascular Endothelial Growth Factor D | 2020 |
Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure.
Topics: Angiotensin II; Animals; Arterio-Arterial Fistula; Heart Failure; Hypertension; Pulmonary Artery; Rats; Rats, Transgenic; Renal Circulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2019 |
Intermedin in Paraventricular Nucleus Attenuates Ang II-Induced Sympathoexcitation through the Inhibition of NADPH Oxidase-Dependent ROS Generation in Obese Rats with Hypertension.
Topics: Adrenomedullin; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Hypertension; Male; MAP Kinase Signaling System; NADPH Oxidases; Obesity; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sympathetic Nervous System | 2019 |
Inhibition of Renin-Angiotensin System from Conception to Young Mature Life Induces Salt-Sensitive Hypertension via Angiotensin II-Induced Sympathetic Overactivity in Adult Male Rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Captopril; Female; Hypertension; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium Chloride, Dietary | 2019 |
Curcumin attenuates migration of vascular smooth muscle cells via inhibiting NFκB-mediated NLRP3 expression in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cell Movement; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Muscle, Smooth, Vascular; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Rats, Inbred SHR; Rats, Wistar | 2019 |
Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediated TMEM16A degradation.
Topics: Acyltransferases; Angiotensin II; Animals; Anoctamin-1; Autophagy; Calcium; Cells, Cultured; Chloride Channels; Down-Regulation; Gene Knockdown Techniques; Hypertension; Male; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2020 |
Loss of smooth muscle CYB5R3 amplifies angiotensin II-induced hypertension by increasing sGC heme oxidation.
Topics: Angiotensin II; Animals; Benzoates; Blood Pressure; Cytochrome-B(5) Reductase; Genotype; Heme; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Nitric Oxide; Oxidation-Reduction; Soluble Guanylyl Cyclase; Transcriptome; Vasodilation | 2019 |
Dipeptidyl peptidase-4 inhibitors can inhibit angiotensin converting enzyme.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enalapril; Female; Glucagon-Like Peptide 1; Humans; Hypertension; Linagliptin; Peptidyl-Dipeptidase A; Protein Binding; Rats; Rats, Sprague-Dawley; Sitagliptin Phosphate | 2019 |
Chronic central miR-29b antagonism alleviates angiotensin II-induced hypertension and vascular endothelial dysfunction.
Topics: Adipokines; Angiotensin II; Animals; Blood Pressure; Cell Movement; Cell Proliferation; Down-Regulation; Endothelial Cells; Endothelin-1; Hypertension; L-Lactate Dehydrogenase; Male; MicroRNAs; Nitric Oxide; Phosphorylation; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Signal Transduction; Up-Regulation | 2019 |
Downregulated microRNA‑133a induces HUVECs injury: Potential role of the (pro) renin receptor in angiotensin II‑dependent hypertension.
Topics: 3' Untranslated Regions; Angiotensin II; Biomarkers; Cell Survival; Fluorescent Antibody Technique; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; MicroRNAs; Receptors, Cell Surface; Renin-Angiotensin System; RNA Interference; Vacuolar Proton-Translocating ATPases | 2019 |
Blockade of intercellular adhesion molecule-1 prevents angiotensin II-induced hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; Aorta; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Intercellular Adhesion Molecule-1; Macrophages; Male; Mice; Mice, Inbred C57BL | 2020 |
Soluble RAGE attenuates AngII-induced endothelial hyperpermeability by disrupting HMGB1-mediated crosstalk between AT1R and RAGE.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Neoplasm; Aorta; Atherosclerosis; Cadherins; Capillary Permeability; Cardiovascular Diseases; Endothelial Cells; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Inflammation; Ligands; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Receptor, Angiotensin, Type 1; RNA, Small Interfering; Signal Transduction | 2019 |
ACE2 and ADAM17 Interaction Regulates the Activity of Presympathetic Neurons.
Topics: ADAM17 Protein; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autonomic Nervous System; Disease Models, Animal; Enzyme Activation; GABAergic Neurons; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Optogenetics; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Random Allocation; Renin-Angiotensin System | 2019 |
Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism.
Topics: Angiotensin II; Animals; Butyric Acid; Cardiomegaly; Cell Line; Cyclooxygenase 2; Dinoprostone; Gene Expression; Gene Knockdown Techniques; Histone Deacetylase 6; Histone Deacetylases; Hypertension; Myocytes, Cardiac; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Brain Prostaglandin D2 Increases Neurogenic Pressor Activity and Mean Arterial Pressure in Angiotensin II-Salt Hypertensive Rats.
Topics: Angiotensin II; Animals; Arterial Pressure; Biomarkers; Brain; Chromatography, Liquid; Cyclooxygenase Inhibitors; Disease Models, Animal; Hypertension; Ketorolac; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Reference Values; Risk Assessment; Sodium Chloride, Dietary; Tandem Mass Spectrometry | 2019 |
A bivalent antihypertensive vaccine targeting L-type calcium channels and angiotensin AT
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channels, L-Type; Disease Models, Animal; Epitopes; Hypertension; Male; Mice, Inbred BALB C; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Vaccination; Vaccines, Combined; Vaccines, Virus-Like Particle | 2020 |
Regulator of G-protein signaling 5 protein protects against anxiety- and depression-like behavior.
Topics: Angiotensin II; Animals; Anxiety; Brain; Depression; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Neuroimmunomodulation; Oxidative Stress; Protective Agents; Receptor, Angiotensin, Type 1; RGS Proteins; Signal Transduction | 2019 |
Central angiotensin II-Protein inhibitor of neuronal nitric oxide synthase (PIN) axis contribute to neurogenic hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Infusions, Intraventricular; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 2020 |
Histone deacetylase inhibitor CG200745 ameliorates high-fat diet-induced hypertension via inhibition of angiotensin II production.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, High-Fat; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hypertension; Male; Mice; Mice, Inbred C57BL; Naphthalenes | 2020 |
Angiotensin II-Induced vascular remodeling and hypertension involves cathepsin L/V- MEK/ERK mediated mechanism.
Topics: Angiotensin II; Animals; Cathepsin L; Cathepsins; Cells, Cultured; Cysteine Endopeptidases; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Vascular Remodeling | 2020 |
Downregulation of Brain Gα12 Attenuates Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Disease Models, Animal; GTP-Binding Protein alpha Subunits, G12-G13; Hypertension; Male; Oligodeoxyribonucleotides; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Plasma Membrane Affiliated AMPA GluA1 in Estrogen Receptor β-containing Paraventricular Hypothalamic Neurons Increases Following Hypertension in a Mouse Model of Post-menopause.
Topics: Angiotensin II; Animals; Cell Membrane; Cyclohexenes; Estrogen Receptor beta; Female; Hypertension; Male; Mice; Neurons; Paraventricular Hypothalamic Nucleus; Postmenopause; Primary Ovarian Insufficiency; Receptors, AMPA; Vinyl Compounds | 2019 |
Hypertension accelerates cerebral tissue PO
Topics: Alzheimer Disease; Angiotensin II; Animals; Cerebral Cortex; Hypertension; Mice; Mice, Transgenic; Oxygen; Partial Pressure; Physical Conditioning, Animal | 2020 |
Ethyl Acetate and Aqueous Fractions of Ziziphus jujuba Prevent Acute Hypertension Induced by Angiotensin II in Rats.
Topics: Acetates; Acute Disease; Angiotensin II; Animals; Hypertension; Male; Plants; Rats; Rats, Wistar; Ziziphus | 2020 |
Blockade of angiotensin-converting enzyme or tumor necrosis factor-α reverses maternal high-fat diet-induced sensitization of angiotensin II hypertension in male rat offspring.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animal Nutritional Physiological Phenomena; Animals; Antihypertensive Agents; Blood Pressure; Brain; Captopril; Diet, High-Fat; Disease Models, Animal; Female; Hypertension; Male; Maternal Nutritional Physiological Phenomena; Pentoxifylline; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Renin-Angiotensin System; Tumor Necrosis Factor Inhibitors | 2020 |
Angiotensin II inhibits DDAH1-nNOS signaling via AT1R and μOR dimerization to modulate blood pressure control in the central nervous system.
Topics: Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Dimerization; Extracellular Signal-Regulated MAP Kinases; Hypertension; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Oligopeptides; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Opioid, mu; Signal Transduction; Solitary Nucleus | 2019 |
Classical Dendritic Cells Mediate Hypertension by Promoting Renal Oxidative Stress and Fluid Retention.
Topics: Angiotensin II; Animals; Dendritic Cells; Disease Models, Animal; Hypertension; Kidney; Membrane Proteins; Mice; Mice, Knockout; Oxidative Stress; T-Lymphocytes | 2020 |
Attenuation of Angiotensin II-Induced Hypertension in BubR1 Low-Expression Mice Via Repression of Angiotensin II Receptor 1 Overexpression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Cycle Proteins; Hypertension; Male; Mice; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1 | 2019 |
Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling.
Topics: Angiotensin II; Animals; Diet, High-Fat; Disease Models, Animal; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Intra-Abdominal Fat; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Peroxidase; Severity of Illness Index; Thioxanthenes; Ventricular Remodeling | 2019 |
Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Hypertension; Male; Nitric Oxide; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 2019 |
Repeated Porphyromonas gingivalis W83 exposure leads to release pro-inflammatory cytokynes and angiotensin II in coronary artery endothelial cells.
Topics: Angiotensin II; Atherosclerosis; Chemokine CCL2; Coronary Vessels; Endothelial Cells; Flow Cytometry; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypertension; Inflammation; Interleukin-6; Lipopolysaccharides; Periodontitis; Porphyromonas gingivalis; Receptor, Angiotensin, Type 1; RNA, Messenger | 2019 |
Kinin B1 Receptor Blockade Prevents Angiotensin II-induced Neuroinflammation and Oxidative Stress in Primary Hypothalamic Neurons.
Topics: Angiotensin II; Animals; Bradykinin B1 Receptor Antagonists; Encephalitis; Hypertension; Hypothalamus; Interleukin-1beta; Interleukin-6; Mice; NADPH Oxidases; Neurons; Oxidative Stress; Receptor, Bradykinin B1; Tumor Necrosis Factor-alpha | 2020 |
MicroRNA-200c-3p inhibits proliferation and migration of renal artery endothelial cells by directly targeting ZEB2.
Topics: Angiotensin II; Animals; Cell Line; Cell Movement; Cell Proliferation; Endothelial Cells; Hypertension; Kidney Diseases; MicroRNAs; Rats; Renal Artery; Up-Regulation; Zinc Finger E-box Binding Homeobox 2 | 2020 |
Renal Anti-Fibrotic Effect of Sodium Glucose Cotransporter 2 Inhibition in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Animals; Benzhydryl Compounds; Fibrosis; Glucosides; Hypertension; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2 Inhibitors | 2020 |
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Topics: Angiotensin II; Animals; Gene Knockout Techniques; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Mice; Oxidative Stress; Protein Binding; Proteolysis; Septins; Signal Transduction; Ubiquitin-Protein Ligases; Ubiquitination; WW Domains; X-Ray Microtomography | 2020 |
Sympathetic Enhancement of Memory T-Cell Homing and Hypertension Sensitization.
Topics: Adoptive Transfer; Adrenergic beta-2 Receptor Antagonists; Angiotensin II; Animals; Bone Marrow; CD8-Positive T-Lymphocytes; Cell Movement; Denervation; Hypertension; Medulla Oblongata; Mice; Mice, Inbred C57BL; Receptors, Adrenergic, beta-2; Superior Cervical Ganglion | 2020 |
Serum Level of HLDF24 Peptide as an Objective Marker of Prehypertension.
Topics: Angiotensin II; Autoantibodies; Biomarkers; Blood Pressure; Endothelins; Female; Humans; Hypertension; Male; Middle Aged; Neoplasm Proteins; Peptide Fragments; Prehypertension; S100 Calcium Binding Protein beta Subunit | 2020 |
6β-Hydroxytestosterone, a metabolite of testosterone generated by CYP1B1, contributes to vascular changes in angiotensin II-induced hypertension in male mice.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cytochrome P-450 CYP1B1; Endothelial Cells; Hydroxytestosterones; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species | 2020 |
C-C Motif Chemokine Receptor 7 Exacerbates Hypertension Through Effects on T Lymphocyte Trafficking.
Topics: Adaptive Immunity; Adoptive Transfer; Angiotensin II; Animals; Chemotaxis, Leukocyte; Dendritic Cells; Genes, RAG-1; Hypertension; Kidney; Lymph Nodes; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Receptors, CCR7; T-Lymphocyte Subsets | 2020 |
Exercise training attenuates angiotensin II-induced vasoconstriction in the aorta of normotensive but not hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Hypertension, Renovascular; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Vasoconstriction | 2020 |
α-Linolenic acid but not linolenic acid protects against hypertension: critical role of SIRT3 and autophagic flux.
Topics: Acetylation; alpha-Linolenic Acid; Angiotensin II; Animals; Antihypertensive Agents; Autophagy; Cells, Cultured; Dietary Supplements; Endothelial Cells; Hypertension; Mice; Mitochondria; Oxidation-Reduction; Rats; Reactive Oxygen Species; Sirtuin 3; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2020 |
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Captopril; Drug Therapy, Combination; Drugs, Chinese Herbal; Endothelin-1; Gene Expression Regulation; Hypertension; Kidney Diseases; Lipid Metabolism; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Inbred SHR | 2020 |
Sex-specific computational models for blood pressure regulation in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Computer Simulation; Disease Models, Animal; Female; Homeostasis; Hypertension; Kidney; Male; Models, Cardiovascular; Natriuresis; Rats, Sprague-Dawley; Rats, Wistar; Renal Artery; Renal Circulation; Sex Characteristics; Sex Factors; Sodium Chloride, Dietary; Sympathetic Nervous System | 2020 |
The association between microRNA-21 and hypertension-induced cardiac remodeling.
Topics: Aged; Angiotensin II; Animals; Animals, Newborn; Apoptosis Regulatory Proteins; Cardiomegaly; Disease Models, Animal; Female; Fibrosis; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Middle Aged; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Signal Transduction; Transcription Factor AP-1; Transforming Growth Factor beta1 | 2020 |
Amphetamine-induced sensitization of hypertension and lamina terminalis neuroinflammation.
Topics: Amphetamine; Angiotensin II; Animals; Blood Pressure; Central Nervous System Stimulants; Diet, High-Fat; Disease Models, Animal; Hypertension; Hypothalamus; Inflammation; Paraventricular Hypothalamic Nucleus; Rats | 2020 |
T-cell senescence accelerates angiotensin II-induced target organ damage.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta; Cardiovascular Diseases; Cell Line; Disease Models, Animal; Homeodomain Proteins; Humans; Hypertension; Immunosenescence; Inflammation Mediators; Interferon-gamma; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Oxidative Stress; Phenotype; Superoxides; T-Lymphocytes; Time Factors | 2021 |
Pharmacodynamics and metabonomics study of Tianma Gouteng Decoction for treatment of spontaneously hypertensive rats with liver-yang hyperactivity syndrome.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; C-Reactive Protein; Drugs, Chinese Herbal; Endothelins; Hyperkinesis; Hypertension; Male; Metabolomics; Norepinephrine; Rats, Inbred SHR; Rats, Sprague-Dawley; Syndrome | 2020 |
Phosphorylation of GATA4 at serine 105 is required for left ventricular remodelling process in angiotensin II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Apoptosis; Cell Proliferation; Echocardiography; Fibroblasts; Fibrosis; GATA4 Transcription Factor; Hypertension; Male; Myocardial Infarction; Myocytes, Cardiac; Phosphorylation; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2020 |
Aortic remodeling is modest and sex-independent in mice when hypertension is superimposed on aging.
Topics: Aging; Angiotensin II; Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Female; Hemodynamics; Hypertension; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phenotype; Sodium Chloride, Dietary | 2020 |
From Rags to Riches: Moving Beyond RAG1 in Studies of Hypertension.
Topics: Angiotensin II; Animals; Homeodomain Proteins; Hypertension; Laboratories; Mice; Mice, Knockout; Phenotype | 2020 |
Lessons Learned From RAG-1-Deficient Mice in Hypertension.
Topics: Angiotensin II; Animals; Homeodomain Proteins; Hypertension; Laboratories; Mice; Mice, Knockout; Phenotype | 2020 |
B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart Failure; Hypertension; Male; Mice; Mice, Inbred C57BL; Paenibacillus; Peptidyl-Dipeptidase A; Recombinant Proteins | 2020 |
Interleukin-17A induces vascular remodeling of small arteries and blood pressure elevation.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Shape; Humans; Hypertension; Interleukin-17; Male; Mesenteric Arteries; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Vascular Remodeling; Vasoconstrictor Agents | 2020 |
Angiotensin-II-mediated AT
Topics: Angiotensin II; Animals; Blood Pressure; Down-Regulation; Glutamic Acid; Hypertension; Medulla Oblongata; N-Methylaspartate; Rats; Receptor, Angiotensin, Type 1; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2020 |
Qian Yang Yu Yin Granule protects against hypertension-induced renal injury by epigenetic mechanism linked to Nicotinamide N-Methyltransferase (NNMT) expression.
Topics: Acetylation; Angiotensin II; Animals; Cell Proliferation; Cortactin; Disease Models, Animal; DNA Methylation; Drugs, Chinese Herbal; Epigenesis, Genetic; Epithelial Cells; HEK293 Cells; Histones; Humans; Hypertension; Kidney; Kidney Diseases; Male; Nicotinamide N-Methyltransferase; Rats, Inbred SHR; Rats, Inbred WKY; S-Adenosylhomocysteine; Sirtuin 1 | 2020 |
Central CYP1B1 (Cytochrome P450 1B1)-Estradiol Metabolite 2-Methoxyestradiol Protects From Hypertension and Neuroinflammation in Female Mice.
Topics: 2-Methoxyestradiol; Angiotensin II; Animals; Astrocytes; Baroreflex; Blood Pressure; Brain; Cytochrome P-450 CYP1B1; Estradiol; Female; Hypertension; Inflammation; Mice; Mice, Knockout; Microglia; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species | 2020 |
Interleukin-9 Deletion Relieves Vascular Dysfunction and Decreases Blood Pressure via the STAT3 Pathway in Angiotensin II-Treated Mice.
Topics: Adult; Aged; Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Cytokines; Humans; Hypertension; Interleukin-9; Mice; Mice, Knockout; Middle Aged; RNA, Messenger; STAT3 Transcription Factor | 2020 |
Regulatory Effects of a Pea-Derived Peptide Leu-Arg-Trp (LRW) on Dysfunction of Rat Aortic Vascular Smooth Muscle Cells against Angiotensin II Stimulation.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Humans; Hypertension; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Oligopeptides; Oxidative Stress; Pisum sativum; Proto-Oncogene Mas; Rats; Superoxides | 2020 |
Prevention of systemic inflammation and neuroprotective effects of Qingda granules against angiotensin II-mediated hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Astrocytes; Brain; Drugs, Chinese Herbal; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents | 2020 |
Qingda granule inhibits angiotensin Ⅱ induced VSMCs proliferation through MAPK and PI3K/AKT pathways.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Vascular Remodeling | 2020 |
Role of complement 3 in renin generation during the differentiation of mesenchymal stem cells to smooth muscle cells.
Topics: Angiotensin II; Animals; Bone Marrow Cells; Cell Differentiation; Complement C3; Epithelial-Mesenchymal Transition; Gene Expression Regulation; Heart; Humans; Hypertension; Kidney; Kruppel-Like Transcription Factors; Liver X Receptors; Mesenchymal Stem Cells; Mice; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System | 2020 |
Altered heart rate variability in angiotensin II-mediated hypertension is associated with impaired autonomic nervous system signaling and intrinsic sinoatrial node dysfunction.
Topics: Angiotensin II; Animals; Autonomic Nervous System; Disease Models, Animal; Electrocardiography; Heart Atria; Heart Rate; Hypertension; Male; Mice; Mice, Inbred C57BL; Sick Sinus Syndrome; Sinoatrial Node | 2020 |
Effects of Estrogen on Cardiac mRNA and LncRNA Expression Profiles in Hypertensive Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression Profiling; Hypertension; Mice, Inbred C57BL; Myocytes, Cardiac; Ovariectomy; Oxidative Stress; RNA, Long Noncoding; RNA, Messenger; Transcriptome; Ventricular Remodeling | 2021 |
[Study on protective effect of vanillic acid from Astragalus membranaceus on hypertensive cardiac remodeling based on network pharmacology screen].
Topics: Angiotensin II; Animals; Astragalus propinquus; Heart; Hypertension; Mice; Protective Agents; Vanillic Acid; Ventricular Remodeling | 2020 |
Purification and identification of angiotensin II type I receptor downregulating peptide from egg white hydrolysate.
Topics: Angiotensin II; Animals; Chromatography, Liquid; Egg White; Hypertension; Peptides; Rats; Receptor, Angiotensin, Type 1; Tandem Mass Spectrometry | 2020 |
VSMC-Specific Deletion of FAM3A Attenuated Ang II-Promoted Hypertension and Cardiovascular Hypertrophy.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Arteries; Blood Pressure; Cardiomegaly; Cells, Cultured; Cytokines; Female; Gene Deletion; Heat Shock Transcription Factors; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Receptors, Purinergic P2; Vasoconstriction; Vasoconstrictor Agents | 2020 |
DNA N
Topics: Adenine; AlkB Homolog 1, Histone H2a Dioxygenase; Angiotensin II; Animals; DNA Methylation; DNA Repair Enzymes; Epigenesis, Genetic; Hypertension; Leukocytes; Mice; Muscle, Smooth, Vascular; Rats; Vascular Remodeling | 2020 |
Might renin-angiotensin system blockers play a role in the COVID-19 pandemic?
Topics: Acute Lung Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Hypertension; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Up-Regulation | 2020 |
Vascular Transcriptome Profiling Reveals Aging-Related Genes in Angiotensin Ⅱ-Induced Hypertensive Mouse Aortas.
Topics: Aging; Angiotensin II; Animals; Aorta; Blood Pressure; Gene Expression Profiling; Gene Ontology; Hypertension; Male; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction | 2020 |
Purinergic P2X
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Male; Purinergic P2X Receptor Antagonists; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Purinergic P2X1; Receptors, Purinergic P2X7; Signal Transduction | 2020 |
The protein Deleted in Breast Cancer-1 (DBC1) regulates vascular response and formation of aortic dissection during Angiotensin II infusion.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Cell Cycle Proteins; Cell Proliferation; Disease Models, Animal; Humans; Hypertension; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Nerve Tissue Proteins; Vascular Endothelial Growth Factor A; Vascular System Injuries | 2020 |
The Role of the Renin-Angiotensin System in Severe Acute Respiratory Syndrome-CoV-2 Infection.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; COVID-19; Down-Regulation; Enzyme Induction; Female; Host-Pathogen Interactions; Humans; Hypertension; Lung; Male; Organ Specificity; Receptors, Coronavirus; Renin-Angiotensin System; Respiratory Distress Syndrome; SARS-CoV-2; Virus Internalization | 2021 |
Association of circulating uric acid and angiotensin-(1-7) in relation to higher blood pressure in adolescents and the influence of preterm birth.
Topics: Adolescent; Angiotensin I; Angiotensin II; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hypertension; Infant, Newborn; Peptide Fragments; Pregnancy; Premature Birth; Renin; Renin-Angiotensin System; Uric Acid | 2020 |
ACE (Angiotensin-Converting Enzyme) Inhibition Reverses Vasoconstriction and Impaired Dilation of Pial Collaterals in Chronic Hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Chronic Disease; Collateral Circulation; Hydralazine; Hypertension; Male; Pia Mater; Random Allocation; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Tetrazoles; Vasoconstriction; Vasodilator Agents; Vasomotor System | 2020 |
Phosphoinositide 3-kinase γ deficiency attenuates kidney injury and fibrosis in angiotensin II-induced hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Disease Models, Animal; Fibroblasts; Fibrosis; Hypertension; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; T-Lymphocytes; Vasoconstrictor Agents | 2020 |
Increased Susceptibility of Mice Lacking Renin-b to Angiotensin II-Induced Organ Damage.
Topics: Angiotensin II; Animals; Blood Pressure; Genetic Predisposition to Disease; Hypertension; Kidney; Male; Mice; Mice, Knockout; Protein Isoforms; Renin; Renin-Angiotensin System | 2020 |
FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway.
Topics: AMP-Activated Protein Kinase Kinases; Angiotensin II; Animals; Aorta; Cell Line; Disease Models, Animal; Fibronectins; Humans; Hypertension; Inflammasomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Protein Kinases; Rats; Signal Transduction; Sirtuin 1 | 2020 |
Diallyl Trisulfide Suppresses Angiotensin II-Induced Vascular Remodeling Via Inhibition of Mitochondrial Fission.
Topics: Allyl Compounds; Angiotensin II; Animals; Cell Movement; Cell Plasticity; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dynamins; Hypertension; Male; Mice, Inbred C57BL; Mitochondria, Muscle; Mitochondrial Dynamics; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Phosphorylation; Reactive Oxygen Species; rho-Associated Kinases; Signal Transduction; Sulfides; Vascular Remodeling | 2020 |
Angiotensin converting enzyme inhibitor potentiates the hypoglycaemic effect of NG-nitro-L-arginine methyl ester (L-NAME) in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Endothelin-1; Enzyme Inhibitors; Hypertension; Hypoglycemic Agents; Insulins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Prostaglandins I; Ramipril; Rats; Rats, Wistar | 2022 |
Hypertensive female Sprague-Dawley rats require an intact nitric oxide synthase system for compensatory increases in renal regulatory T cells.
Topics: Angiotensin II; Animals; Blood Pressure; Enzyme Inhibitors; Female; Hypertension; Kidney; Kidney Function Tests; Male; Nitric Oxide Synthase; Rats, Sprague-Dawley; T-Lymphocytes, Regulatory | 2020 |
Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency.
Topics: Aging; Angiotensin II; Animals; Glucuronidase; Hypertension; Klotho Proteins; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin-Light-Chain Phosphatase; Sodium Chloride, Dietary; Wnt-5a Protein | 2020 |
Class switching and high-affinity immunoglobulin G production by B cells is dispensable for the development of hypertension in mice.
Topics: Angiotensin II; Animals; Antibody Affinity; Aorta; Blood Pressure; Cells, Cultured; Cytidine Deaminase; Desoxycorticosterone Acetate; Disease Models, Animal; Female; Hypertension; Immunoglobulin Class Switching; Immunoglobulin G; Immunoglobulin Heavy Chains; Immunoglobulin M; Kidney; Male; Memory B Cells; Mice, Inbred C57BL; Mice, Knockout; Sodium Chloride, Dietary | 2021 |
T cell aging in hypertension.
Topics: Aging; Angiotensin II; Cellular Senescence; Humans; Hypertension; T-Lymphocytes | 2021 |
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Topics: Acetylation; Angiotensin II; Animals; Cell Movement; Cell Proliferation; Hypertension; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Sirtuin 1; STAT3 Transcription Factor; Ubiquitin-Protein Ligases | 2020 |
Exercise-induced hypertension is associated with angiotensin II activity and total nitric oxide.
Topics: Adult; Angiotensin II; Blood Pressure; Exercise; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Renin-Angiotensin System; Running | 2020 |
Primary Aldosteronism: The Next Decade.
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Ramipril; Renin | 2020 |
Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice-Brief Report.
Topics: Amino Acid Substitution; Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Blood Pressure; Disease Models, Animal; Female; Hepatocytes; Humans; Hypertension; Male; Mice, Knockout; Plaque, Atherosclerotic; Receptors, LDL; Renin; Species Specificity | 2020 |
Irbesartan may relieve renal injury by suppressing Th22 cells chemotaxis and infiltration in Ang II-induced hypertension.
Topics: Angiotensin II; Animals; Cell Differentiation; Cell Survival; Chemotaxis; Cytokines; Hypertension; Irbesartan; Kidney; Male; Mice, Inbred C57BL; T-Lymphocytes; T-Lymphocytes, Helper-Inducer | 2020 |
Alamandine attenuates angiotensin II-induced vascular fibrosis via inhibiting p38 MAPK pathway.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertension; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling | 2020 |
MiR-124-3p reduces angiotensin II-dependent hypertension by down-regulating EGR1.
Topics: Angiotensin II; Apoptosis; Early Growth Response Protein 1; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; MicroRNAs | 2021 |
Honokiol ameliorates angiotensin II-induced hypertension and endothelial dysfunction by inhibiting HDAC6-mediated cystathionine γ-lyase degradation.
Topics: Acetylation; Angiotensin II; Animals; Aorta; Biphenyl Compounds; Cystathionine gamma-Lyase; Endothelial Cells; HEK293 Cells; Histone Deacetylase 6; Humans; Hydrogen Sulfide; Hypertension; Lignans; Male; Mice; Mice, Inbred C57BL; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Proteolysis; Recombinant Proteins | 2020 |
Renal Perfusion Pressure Determines Infiltration of Leukocytes in the Kidney of Rats With Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Flow Cytometry; Hypertension; Kidney; Leukocytes; Monocytes; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Renal Artery; Vasoconstrictor Agents | 2020 |
Interplay Between Statins, Cav1 (Caveolin-1), and Aldosterone.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Caveolin 1; Cholesterol; Correlation of Data; Dyslipidemias; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Pharmacogenomic Testing; Pharmacogenomic Variants; Polymorphism, Single Nucleotide | 2020 |
Brain Testosterone-CYP1B1 (Cytochrome P450 1B1) Generated Metabolite 6β-Hydroxytestosterone Promotes Neurogenic Hypertension and Inflammation.
Topics: Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP1B1; Hydroxytestosterones; Hypertension; Mice; Mice, Knockout; Neurogenic Inflammation; Paraventricular Hypothalamic Nucleus; Reactive Oxygen Species; Receptors, Androgen; Receptors, G-Protein-Coupled | 2020 |
Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Disease Progression; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging, Cine; Male; Mice, Inbred C57BL; Myocardium; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2020 |
COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Anticoagulants; Cardiovascular Diseases; COVID-19; Humans; Hypertension; Models, Theoretical; Peptide Fragments; Renin-Angiotensin System; Respiration; Risk Factors; Venous Thromboembolism; Virus Internalization | 2020 |
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor, lowers L-NAME-induced hypertension through suppression of angiotensin-converting enzyme in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Epoxide Hydrolases; Hypertension; Male; NG-Nitroarginine Methyl Ester; Phenylurea Compounds; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2020 |
Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cognitive Dysfunction; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Macrophages; Male; Mice; Microglia; Organic Chemicals | 2020 |
Platelets and renal failure in the SARS-CoV-2 syndrome.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme 2; Blood Platelets; Comorbidity; COVID-19; Diabetes Mellitus; Female; Fibrin Fibrinogen Degradation Products; Glomerular Filtration Rate; Humans; Hypertension; Male; Mean Platelet Volume; Middle Aged; Pandemics; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2; Thrombocytopenia; Thrombophilia; Young Adult | 2021 |
Calcitriol inhibits COX-1 and COX-2 expressions of renal vasculature in hypertension: Reactive oxygen species involved?
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcitriol; Cyclic N-Oxides; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Endothelium, Vascular; Free Radical Scavengers; Humans; Hypertension; Losartan; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptors, Calcitriol; Renal Artery; Spin Labels; Vasodilation | 2021 |
Antihypertensive properties of a traditional Chinese medicine GAO-ZI-YAO in elderly spontaneous hypertensive rats.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Cytokines; Drugs, Chinese Herbal; Endothelin-1; Hypertension; Irbesartan; Male; Medicine, Chinese Traditional; Nitric Oxide; Rats; Rats, Inbred SHR; Vascular Endothelial Growth Factor A | 2020 |
Functional interactions between complex I and complex II with nNOS in regulating cardiac mitochondrial activity in sham and hypertensive rat hearts.
Topics: Angiotensin II; Animals; Cells, Cultured; Citrulline; Electron Transport Complex I; Electron Transport Complex II; Enzyme Inhibitors; Hypertension; Male; Malonates; Mitochondria, Heart; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Rotenone; Thiourea | 2020 |
Caveolin‑1 modulates hypertensive vascular remodeling via regulation of the Notch pathway.
Topics: Angiotensin II; Animals; Brain; Caveolin 1; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Gene Expression Regulation; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Rats; Receptor, Notch1; Signal Transduction; Up-Regulation; Vascular Remodeling | 2020 |
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Atherosclerosis; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Mice; Protein-Lysine 6-Oxidase; Quercetin | 2020 |
Serum ACE2, Angiotensin II, and Aldosterone Levels Are Unchanged in Patients With COVID-19.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure Determination; COVID-19; Female; Germany; Humans; Hypertension; Male; Middle Aged; Outcome Assessment, Health Care; Potassium; Prospective Studies; Renin-Angiotensin System; SARS-CoV-2 | 2021 |
A new mechanism for the sex differences in angiotensin II-induced hypertension: the role of macula densa NOS1β-mediated tubuloglomerular feedback.
Topics: Angiotensin II; Animals; Feedback; Female; Glomerular Filtration Rate; Hypertension; Kidney Cortex; Kidney Glomerulus; Kidney Tubules; Male; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Sex Characteristics | 2020 |
Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)-Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cells, Cultured; Disease Models, Animal; Fibroblasts; Growth Differentiation Factor 6; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 2; Paracrine Communication; Signal Transduction; Vascular Remodeling | 2021 |
Effects of Testosterone Deficiency and Angiotensin II-Induced Hypertension on the Biomechanics of Intramural Coronary Arteries.
Topics: Angiotensin II; Animals; Biomechanical Phenomena; Blood Pressure; Coronary Vessels; Hypertension; Male; Rats; Rats, Sprague-Dawley; Testosterone | 2020 |
Mas Receptor Activation Contributes to the Improvement of Nitric Oxide Bioavailability and Vascular Remodeling During Chronic AT1R (Angiotensin Type-1 Receptor) Blockade in Experimental Hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Hypertension; Imidazoles; Mesenteric Arteries; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Tetrazoles; Vascular Remodeling; Vasodilation | 2020 |
Methylation-dependent antioxidant-redox imbalance regulates hypertensive kidney injury in aging.
Topics: Aging; Angiotensin II; Animals; Antioxidants; Hypertension; Kidney; Methylation; Mice; Mice, Inbred C57BL; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress | 2020 |
Novel antihypertensive action of rutin is mediated via inhibition of angiotensin converting enzyme/mineralocorticoid receptor/angiotensin 2 type 1 receptor (ATR1) signaling pathways in uninephrectomized hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Humans; Hypertension; Peptidyl-Dipeptidase A; Rats; Receptors, Mineralocorticoid; Rutin | 2020 |
Sirtuin 3 governs autophagy-dependent glycolysis during Angiotensin II-induced endothelial-to-mesenchymal transition.
Topics: Angiotensin II; Animals; Autophagy; Autophagy-Related Protein 5; Cells, Cultured; Endothelial Cells; Fibrosis; Glycolysis; Hypertension; Mesenchymal Stem Cells; Mice, Knockout; Mice, Transgenic; Mitochondria; Myocytes, Smooth Muscle; Pyruvate Kinase; Sirtuin 3 | 2020 |
Editing of the myosin phosphatase regulatory subunit suppresses angiotensin II induced hypertension via sensitization to nitric oxide mediated vasodilation.
Topics: Angiotensin II; Animals; Hypertension; Leucine Zippers; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Mutation; Myosin-Light-Chain Phosphatase; Nitric Oxide; Vasodilation | 2021 |
The Possible Regulatory Mechanisms of Aqueous, Ethyl Acetate and NHexane Fractions of the Ribes khorassanicum Extract on Acute Hypertension in Rats.
Topics: Acetates; Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Disease Models, Animal; Hexanes; Hypertension; Losartan; Male; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats; Rats, Wistar; Ribes; Signal Transduction; Water | 2021 |
Blockade of ERK1/2 activation with U0126 or PEP7 reduces sodium appetite and angiotensin II-induced pressor responses in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Appetite; Butadienes; Captopril; Disease Models, Animal; Furosemide; Humans; Hypertension; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sodium | 2021 |
Platelets Promote Ang II (Angiotensin II)-Induced Atrial Fibrillation by Releasing TGF-β1 (Transforming Growth Factor-β1) and Interacting With Fibroblasts.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Atrial Remodeling; Blood Platelets; Clopidogrel; Fibroblasts; Humans; Hypertension; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Platelet Activation; Platelet Aggregation Inhibitors; Transforming Growth Factor beta1 | 2020 |
Evidence that angiotensin II does not directly stimulate the MD2-TLR4 innate inflammatory pathway.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Line; Chemokine CCL2; Humans; Hypertension; Inflammation; Kidney; Lymphocyte Antigen 96; NF-kappa B; Palmitates; Rats; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Toll-Like Receptor 4 | 2021 |
Lymphangiogenic therapy prevents cardiac dysfunction by ameliorating inflammation and hypertension.
Topics: Angiotensin II; Animals; Biomarkers; Endothelial Cells; Gene Knock-In Techniques; Genome-Wide Association Study; Green Fluorescent Proteins; Heart Diseases; Homeodomain Proteins; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Myocardium; Random Allocation; Sequence Analysis, RNA; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor C | 2020 |
Predator Scent-Induced Sensitization of Hypertension and Anxiety-like Behaviors.
Topics: Angiotensin II; Animals; Anxiety; Disease Models, Animal; Hypertension; Odorants; Rats; Rats, Sprague-Dawley | 2022 |
SIRT3 Deficiency Sensitizes Angiotensin-II-Induced Renal Fibrosis.
Topics: Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Humans; Hypertension; Kidney; Kidney Diseases; Mice; Sirtuin 3 | 2020 |
Cardiac and renal protective effects of 2,5-dimethylcelecoxib in angiotensin II and high-salt-induced hypertension model mice.
Topics: Angiotensin II; Animals; Humans; Hypertension; Kidney; Mice; Pyrazoles; Sulfonamides | 2021 |
Site-1 Protease-Derived Soluble (Pro)Renin Receptor Contributes to Angiotensin II-Induced Hypertension in Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Mice; Proprotein Convertases; Prorenin Receptor; Pyrrolidines; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Serine Endopeptidases | 2021 |
Central Ang II (Angiotensin II)-Mediated Sympathoexcitation: Role for HIF-1α (Hypoxia-Inducible Factor-1α) Facilitated Glutamatergic Tone in the Paraventricular Nucleus of the Hypothalamus.
Topics: Angiotensin II; Animals; Baroreflex; Glutamic Acid; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sympathetic Nervous System | 2021 |
Tumor Necrosis Factor α Receptor Type 1 Activation in the Hypothalamic Paraventricular Nucleus Contributes to Glutamate Signaling and Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Animals; Glutamic Acid; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction | 2021 |
SIRT3 (Sirtuin-3) Prevents Ang II (Angiotensin II)-Induced Macrophage Metabolic Switch Improving Perivascular Adipose Tissue Function.
Topics: Acetylation; Adipose Tissue, Brown; Angiotensin II; Animals; Cell Plasticity; Disease Models, Animal; Energy Metabolism; Fibrosis; HEK293 Cells; Humans; Hypertension; Inflammasomes; Interleukin-1beta; Lactic Acid; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Panniculitis; Phenotype; Pyruvate Dehydrogenase (Lipoamide); Signal Transduction; Sirtuin 3 | 2021 |
Sex hormone-like Effects of Icariin on T-cells immune modulation in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Castration; Epimedium; Estradiol; Estrogen Receptor beta; Female; Flavonoids; Heart Rate; Hypertension; Interleukin-17; Leukocytes, Mononuclear; Male; Phytosterols; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Androgen; Spleen; T-Lymphocytes; Testosterone; Tumor Necrosis Factor-alpha | 2021 |
HDAC5 inhibition reduces angiotensin II-induced vascular contraction, hypertrophy, and oxidative stress in a mouse model.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; Benzamides; Cells, Cultured; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxadiazoles; Oxidative Stress; rho-Associated Kinases; rhoA GTP-Binding Protein; Vascular Remodeling; Vasoconstriction | 2021 |
C1q/TNF-related protein-9 is elevated in hypertension and associated with the occurrence of hypertension-related atherogenesis.
Topics: Adipokines; Adiponectin; Adult; Aged; Angiotensin II; Animals; Atherosclerosis; Carotid Artery Diseases; Complement C1q; Endothelial Cells; Female; Glycoproteins; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Middle Aged | 2021 |
Qingda granule attenuates angiotensin II-induced cardiac hypertrophy and apoptosis and modulates the PI3K/AKT pathway.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Cell Line; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Gene Regulatory Networks; Hypertension; Hypertrophy, Left Ventricular; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction | 2021 |
Direct Actions of AT
Topics: Angiotensin II; Animals; Cardiomegaly; Hypertension; Mice; Mice, Knockout; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Vascular Resistance | 2021 |
No evidence for brain renin-angiotensin system activation during DOCA-salt hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Brain; Brain Stem; Desoxycorticosterone Acetate; Hypertension; Male; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Valsartan | 2021 |
S1P (Site-1 Protease)-Induced Release of the Soluble Prorenin Receptor in Hypertension: Do All Roads Lead to Ang II (Angiotensin II)?
Topics: Angiotensin II; Humans; Hypertension; Proprotein Convertases; Prorenin Receptor; Receptors, Cell Surface; Serine Endopeptidases | 2021 |
Gastrin, via activation of PPARα, protects the kidney against hypertensive injury.
Topics: Angiotensin II; Animals; Apoptosis; Fibrosis; Gastrins; Humans; Hypertension; Hypertension, Renal; Jurkat Cells; Kidney Tubules, Proximal; Mice; Mice, Knockout; Nephritis; Phagocytosis; PPAR alpha; Receptors, Cholecystokinin; RNA, Small Interfering; Signal Transduction; Ureteral Obstruction | 2021 |
LncRNA SNHG12 alleviates hypertensive vascular endothelial injury through miR-25-3p/SIRT6 pathway.
Topics: Angiotensin II; Animals; Base Sequence; Down-Regulation; Endothelium, Vascular; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Male; Mice, Inbred C57BL; MicroRNAs; RNA, Long Noncoding; Signal Transduction; Sirtuins | 2021 |
Adaptation to 5 weeks of intermittent local vascular pressure increments; mechanisms to be considered in the development of primary hypertension?
Topics: Adaptation, Physiological; Adult; Angiotensin II; Arm; Arterial Pressure; Endothelin-1; Humans; Hypertension; Male; Matrix Metalloproteinase 7; Regional Blood Flow; Time Factors; Vascular Remodeling; Vascular Stiffness; Young Adult | 2021 |
Renal Natriuretic Peptide Receptor-C Deficiency Attenuates NaCl Cotransporter Activity in Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Female; Hypertension; Kidney; Kidney Tubules, Distal; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Protein Serine-Threonine Kinases; Receptors, Atrial Natriuretic Factor; Renin-Angiotensin System; Signal Transduction; Sodium; Solute Carrier Family 12, Member 3 | 2021 |
NAMPT/SIRT1 Attenuate Ang II-Induced Vascular Remodeling and Vulnerability to Hypertension by Inhibiting the ROS/MAPK Pathway.
Topics: Angiotensin II; Animals; Case-Control Studies; Female; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Sirtuin 1; Vascular Remodeling | 2020 |
Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula.
Topics: Angiotensin II; Animals; Arteriovenous Fistula; Female; Heart Failure; Hypertension; Kidney; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Sympathectomy | 2021 |
Inhibition of plasma kallikrein mitigates experimental hypertension-enhanced cerebral hematoma expansion.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Hemorrhage; Crotalid Venoms; Disease Models, Animal; Hypertension; Lectins, C-Type; Male; Mice; Plasma Kallikrein; Treatment Outcome | 2021 |
A Flounder Fish Peptide Shows Anti-Hypertensive Effects by Suppressing the Renin-Angiotensin-Aldosterone System and Endothelin-1.
Topics: Administration, Oral; Aldosterone; Amino Acid Sequence; AMP-Activated Protein Kinases; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Endothelin-1; Fish Proteins; Flounder; Gene Expression Regulation; Hypertension; Kidney; Male; Muscles; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction | 2021 |
Expression of Cyr61 in ApoE
Topics: Amides; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Apolipoproteins E; Blood Pressure; Cysteine-Rich Protein 61; Fumarates; Gene Expression Regulation; Humans; Hypertension; Irbesartan; Mice; Mice, Knockout; Renal Artery; Renal Artery Obstruction | 2021 |
Clathriolide from marine demosponge
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Hypertension; Lactones; Peptidyl-Dipeptidase A; Porifera | 2022 |
Berberine ameliorates vascular dysfunction by a global modulation of lncRNA and mRNA expression profiles in hypertensive mouse aortae.
Topics: Angiotensin II; Animals; Aorta; Berberine; Blood Pressure; Gene Expression Profiling; Hypertension; Male; Mice; RNA, Long Noncoding; RNA, Messenger; Transcriptome | 2021 |
Proximal Tubule-Specific Deletion of Angiotensin II Type 1a Receptors in the Kidney Attenuates Circulating and Intratubular Angiotensin II-Induced Hypertension in PT-
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Knockout Techniques; Glomerular Filtration Rate; Hypertension; Kidney Tubules, Proximal; Mice; Natriuresis; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Hydrogen Exchanger 3 | 2021 |
Differential biomechanical responses of elastic and muscular arteries to angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Arteries; Elastin; Hypertension; Mesenteric Arteries; Mice; Pulse Wave Analysis | 2021 |
Toll-like receptor 2 signaling deficiency in cardiac cells ameliorates Ang II-induced cardiac inflammation and remodeling.
Topics: Angiotensin II; Animals; Bone Marrow Transplantation; Cell Line; Gene Knockdown Techniques; Hypertension; Immunity, Innate; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; Myocardium; Myocytes, Cardiac; Rats; Signal Transduction; Toll-Like Receptor 2; Translational Research, Biomedical; Vascular Remodeling | 2021 |
The Angiotensin II Type 1(AT1) Receptor and Cardiac Hypertrophy: Did We Have It Wrong All Along?
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Hypertension; Mice; Receptor, Angiotensin, Type 1 | 2021 |
Role of chymase in blood pressure control, plasma and tissue angiotensin II, renal Haemodynamics, and excretion in
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chymases; Glomerular Filtration Rate; Hemodynamics; Hypertension; Ilium; Kidney; Male; Oligopeptides; Perfusion; Potassium; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Sodium | 2021 |
High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons.
Topics: Angiotensin II; Animals; Cell Membrane; Cytoskeleton; Disease Models, Animal; Excitatory Postsynaptic Potentials; Hypertension; Male; Mechanotransduction, Cellular; Neurons; Osmosis; Probability; Rats, Wistar; Sodium Chloride, Dietary; Synapses; Vasopressins | 2021 |
Association of maternal angiotensin II type 1 and type 2 receptor combination genotypes with susceptibility to early-onset preeclampsia.
Topics: Angiotensin II; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2022 |
MicroRNA-212-5p and its target PAFAH1B2 suppress vascular proliferation and contraction via the downregulation of RhoA.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Angiotensin II; Animals; Antagomirs; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclin D1; Disease Models, Animal; Down-Regulation; Hypertension; MicroRNAs; Muscle Contraction; Muscle, Smooth, Vascular; Rats; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; Vascular Remodeling | 2021 |
Outside-in Signaling by Adventitial Fibroblasts.
Topics: Angiotensin II; Fibroblasts; Humans; Hypertension; Muscle, Smooth, Vascular; Paracrine Communication; Vascular Remodeling | 2021 |
The subfornical organ drives hypertension in polycystic kidney disease via the hypothalamic paraventricular nucleus.
Topics: Angiotensin II; Animals; Hypertension; Paraventricular Hypothalamic Nucleus; Polycystic Kidney Diseases; Rats; Rats, Inbred Lew; Receptors, Ionotropic Glutamate; Subfornical Organ | 2022 |
An LC-MS/MS assay for analysis of equilibrium angiotensin II in human serum.
Topics: Adult; Angiotensin II; Chromatography, Liquid; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Tandem Mass Spectrometry | 2021 |
Time-Dependent Effects of Individual and Combined Treatments With Nebivolol, Lisinopril, and Valsartan on Blood Pressure and Vascular Reactivity to Angiotensin II and Norepinephrine.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Combinations; Hypertension; Lisinopril; Male; Nebivolol; Norepinephrine; Rats, Inbred SHR; Rats, Wistar; Time; Valsartan; Vascular Resistance; Vasoconstrictor Agents | 2021 |
CRIP1 expression in monocytes related to hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Cell Differentiation; Cohort Studies; Disease Models, Animal; Humans; Hypertension; Macrophages; Male; Monocytes; NG-Nitroarginine Methyl Ester; Spleen; Transcriptome | 2021 |
Newly developed radioimmunoassay for Human Angiotensin-(1-12) measurements in plasma and urine.
Topics: Aged; Angiotensin II; Angiotensinogen; Antibodies; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Chymases; Female; Gene Expression Regulation; Humans; Hypertension; Limit of Detection; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Recombinant Proteins; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Revisiting the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Chymases; Diabetic Nephropathies; Gene Expression Regulation; Humans; Hypertension; Kidney; Peptide Fragments; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice.
Topics: Adult; Angiotensin II; Animals; Cell Line; Female; Humans; Hypertension; Kidney Diseases; Male; Mice; Mice, Transgenic; Middle Aged; Renin-Angiotensin System; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Inhibition of YAP activation attenuates renal injury and fibrosis in angiotensin II hypertensive mice.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Chemokine CCL2; Fibrosis; Hypertension; Hypertension, Renal; Male; Mice; Mice, Inbred C57BL; Nephritis; Photosensitizing Agents; Protein Serine-Threonine Kinases; Signal Transduction; Transforming Growth Factor beta; Vasoconstrictor Agents; Verteporfin; YAP-Signaling Proteins | 2021 |
Serum microRNA-30d is a sensitive biomarker for angiotensin II-induced cardiovascular complications in rats.
Topics: Angiotensin II; Animals; Biomarkers; Cardiomegaly; Hypertension; MicroRNAs; Myocytes, Cardiac; Natriuretic Peptide, Brain; Rats | 2021 |
circACTA2 mediates Ang II-induced VSMC senescence by modulation of the interaction of ILF3 with CDK4 mRNA.
Topics: Angiotensin II; Cell Line; Cellular Senescence; Cyclin-Dependent Kinase 4; HEK293 Cells; Humans; Hypertension; Myocytes, Smooth Muscle; Nuclear Factor 90 Proteins; RNA, Circular; RNA, Messenger; RNA, Small Interfering | 2021 |
Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Kidney Diseases; Male; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Prorenin Receptor; Proton-Translocating ATPases; Receptors, Cell Surface; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation; Water-Electrolyte Balance | 2021 |
In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism.
Topics: Age Factors; Aging; Angiotensin II; Animals; Blood Pressure; Body Weight; Endothelium, Vascular; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Hypertension; Mice; Receptor, Angiotensin, Type 2 | 2021 |
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Angiotensin II; Animals; Antithrombins; Atrial Fibrillation; Body Mass Index; Catheter Ablation; Cohort Studies; Dabigatran; Dogs; Embolism; Factor Xa Inhibitors; Female; Genotype; Hemorrhage; Humans; Hypertension; Hypertrophy, Left Ventricular; Incidence; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Middle Aged; Norepinephrine; Obesity; Polymorphism, Single Nucleotide; Retrospective Studies; Rivaroxaban; Stroke; Sympathectomy | 2017 |
Mdivi-1, a mitochondrial fission inhibitor, reduces angiotensin-II- induced hypertension by mediating VSMC phenotypic switch.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cells, Cultured; Dynamins; Hypertension; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Quinazolinones; Reactive Oxygen Species | 2021 |
Increased angiotensin II formation in the brain modulates cardiovascular homeostasis and erythropoiesis.
Topics: Angiotensin II; Animals; Brain; Erythropoiesis; Homeostasis; Hypertension; Kidney; Mice; Mice, Transgenic; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2021 |
Mutagenesis of the Cleavage Site of Pro Renin Receptor Abrogates Angiotensin II-Induced Hypertension in Mice.
Topics: Angiotensin II; Animals; Base Sequence; Binding Sites; Blood Pressure; Cells, Cultured; CRISPR-Cas Systems; Hypertension; Mice, Knockout; Mutagenesis; Protein Precursors; Receptors, Cell Surface; Renin; Renin-Angiotensin System | 2021 |
Direct comparison of inorganic nitrite and nitrate on vascular dysfunction and oxidative damage in experimental arterial hypertension.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitrites; Oxidative Stress | 2021 |
CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice.
Topics: ADP-ribosyl Cyclase 1; Angiotensin II; Animals; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Extracellular Vesicles; Humans; Hypertension; Membrane Glycoproteins; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Signal Transduction; Vascular Remodeling | 2021 |
MicroRNA-532-5p-programmed cell death protein 4 (PDCD4) axis regulates angiotensin II-induced human umbilical vein endothelial cell apoptosis and proliferation.
Topics: Angiotensin II; Apoptosis; Apoptosis Regulatory Proteins; Cell Proliferation; Cells, Cultured; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; MicroRNAs; RNA-Binding Proteins; S Phase Cell Cycle Checkpoints; Signal Transduction | 2021 |
Inactivation of Interleukin-4 Receptor α Signaling in Myeloid Cells Protects Mice From Angiotensin II/High Salt-Induced Cardiovascular Dysfunction Through Suppression of Fibrotic Remodeling.
Topics: Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Hypertension; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; Myocardium; Receptors, Cell Surface; Signal Transduction; Sodium Chloride, Dietary; Ventricular Remodeling | 2021 |
Clitoria ternatea L. extract prevents kidney damage by suppressing the Ang II/Nox4/oxidative stress cascade in l-NAME-induced hypertension model of rats.
Topics: Angiotensin II; Animals; Clitoria; Hypertension; Kidney; NADPH Oxidase 4; NG-Nitroarginine Methyl Ester; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley | 2021 |
Characterization of the Renin-Angiotensin-Aldosterone System in Young Healthy Black Adults: The African Prospective Study on the Early Detection and Identification of Hypertension and Cardiovascular Disease (African-PREDICT Study).
Topics: Adult; Aldosterone; Angiotensin II; Black People; Blood Pressure; Cardiovascular Diseases; Early Diagnosis; Female; Healthy Volunteers; Humans; Hypertension; Male; Prospective Studies; Renin-Angiotensin System; White People; Young Adult | 2021 |
Sirtuin 3 deficiency aggravates angiotensin II-induced hypertensive cardiac injury by the impairment of lymphangiogenesis.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Heart Injuries; Hypertension; Lymphangiogenesis; Male; Mice; Mice, Knockout; Sirtuin 3; Vascular Endothelial Growth Factor Receptor-3; Vasoconstrictor Agents | 2021 |
PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice.
Topics: Adipocytes; Angiotensin II; Animals; Heart; Hypertension; Lymphokines; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Mice, Transgenic; Myocardium; Obesity; Platelet-Derived Growth Factor; Urokinase-Type Plasminogen Activator; Ventricular Remodeling | 2021 |
Testosterone attenuates hypoxia-induced hypertension by affecting NRF1-mediated transcriptional regulation of ET-1 and ACE.
Topics: Angiotensin II; Animals; Endothelial Cells; Endothelin-1; Hypertension; Hypoxia; Nuclear Respiratory Factor 1; Peptidyl-Dipeptidase A; Rats; Testosterone | 2021 |
Sex differences in angiotensin II-induced hypertension and kidney injury: role of AT1a receptors in the proximal tubule of the kidney.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterial Pressure; Disease Models, Animal; Female; Fibrosis; Hypertension; Kidney Diseases; Kidney Tubules, Proximal; Losartan; Male; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sex Characteristics; Sex Factors; Signal Transduction | 2021 |
Activation of the intestinal tissue renin-angiotensin system by transient sodium loading in salt-sensitive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary | 2022 |
Central role of c-Src in NOX5- mediated redox signalling in vascular smooth muscle cells in human hypertension.
Topics: Actins; Angiotensin II; Animals; Cells, Cultured; Humans; Hypertension; Melitten; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 5; Oxidation-Reduction; Protein-Tyrosine Kinases; Reactive Oxygen Species; RNA, Small Interfering | 2022 |
Fibroblast-specific IKK-β deficiency ameliorates angiotensin II-induced adverse cardiac remodeling in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Fibrosis; Gene Knockdown Techniques; Heart Rate; Hypertension; I-kappa B Kinase; Inflammation; Macrophages; Male; Mice; Myocarditis; Myocardium; Organ Size; Protective Factors; Signal Transduction; Ventricular Remodeling | 2021 |
Iron chelation suppresses secondary bleeding after intracerebral hemorrhage in angiotensin II-infused mice.
Topics: Angiotensin II; Animals; Cerebral Hemorrhage; Deferoxamine; Drug Combinations; Hemoglobins; Hypertension; Intracranial Hemorrhages; Iron Chelating Agents; Iron Overload; Iron-Dextran Complex; Male; Mice; Mice, Inbred C57BL; Microinjections; Muscle Contraction; Muscle, Smooth, Vascular; Neostriatum; Polyvinyls; Tantalum; Vasoconstrictor Agents | 2021 |
Krüppel-Like Factor 15/Interleukin 11 Axis-Mediated Adventitial Remodeling Depends on Extracellular Signal-Regulated Kinases 1 and 2 Activation in Angiotensin II-Induced Hypertension.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Thoracic; Disease Models, Animal; Fibroblasts; Fibrosis; HEK293 Cells; Humans; Hypertension; Inflammation Mediators; Interleukin-11; Kruppel-Like Transcription Factors; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2021 |
Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers-Relevance to COVID-19.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; COVID-19; COVID-19 Drug Treatment; Crystallography, X-Ray; Drug Discovery; Humans; Hypertension; Male; Models, Molecular; Rabbits; Receptor, Angiotensin, Type 1; Vasoconstriction | 2021 |
Glucagon-like peptide-1 attenuates cardiac hypertrophy via the AngII/AT1R/ACE2 and AMPK/mTOR/p70S6K pathways.
Topics: Adenylate Kinase; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomegaly; Cardiotonic Agents; Cell Line; Disease Models, Animal; Glucagon-Like Peptide 1; Hypertension; Liraglutide; Male; Morpholines; Myocytes, Cardiac; Piperidines; Rats; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Triazines; Uracil | 2021 |
Resolvin-D1 attenuation of angiotensin II-induced cardiac inflammation in mice is associated with prevention of cardiac remodeling and hypertension.
Topics: Angiotensin II; Animals; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Docosahexaenoic Acids; Gene Expression Regulation; Humans; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Mice; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Ventricular Remodeling | 2021 |
Blocking of interleukin-1 suppresses angiotensin II-induced renal injury.
Topics: Angiotensin II; Animals; Antibodies; Blood Pressure; Bosentan; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Fibrosis; Humans; Hypertension; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction | 2021 |
Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Cells, Cultured; Electrolytes; Endothelial Cells; Glycine; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Isoquinolines; Kidney Glomerulus; Male; Mice; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proteinuria; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Urine; Vascular Remodeling | 2021 |
Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice.
Topics: Aging; Angiotensin II; Animals; Cerebral Hemorrhage; Hypertension; Matrix Metalloproteinase 9; Mice | 2021 |
Sirtuin1 contributes to the overexpression of Giα proteins and hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Sirtuin 1 | 2022 |
6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A
Topics: Angiotensin II; Animals; Cytochrome P-450 CYP1B1; Cytokines; Dinoprostone; Group IV Phospholipases A2; Hydroxytestosterones; Hypertension; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Thromboxane A2 | 2021 |
The promoting role of Cx43 on the proliferation and migration of arterial smooth muscle cells for angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Cell Proliferation; Connexin 43; Hypertension; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats | 2021 |
Thrombin Inhibition Prevents Endothelial Dysfunction and Reverses 20-HETE Overproduction without Affecting Blood Pressure in Angiotensin II-Induced Hypertension in Mice.
Topics: Angiotensin II; Animals; Antithrombins; Chromatography, Liquid; Dabigatran; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Hypertension; Intercellular Adhesion Molecule-1; Male; Mice; Nitric Oxide; Tandem Mass Spectrometry; Vascular Remodeling; von Willebrand Factor | 2021 |
Comparative beneficial effects of nebivolol and nebivolol/valsartan combination against mitochondrial dysfunction in angiotensin II-induced pathology in H9c2 cardiomyoblasts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Cell Culture Techniques; Drug Combinations; Heart; Hypertension; Inflammation; Mechanistic Target of Rapamycin Complex 1; Mitochondria; Myoblasts, Cardiac; Myocardium; Nebivolol; Organelle Biogenesis; Oxidative Stress; Rats; Reactive Oxygen Species; Valsartan | 2021 |
l-Carnitine ameliorates the oxidative stress response to angiotensin II by modulating NADPH oxidase through a reduction in protein kinase c activity and NF-κB translocation to the nucleus.
Topics: Angiotensin II; Animals; Carnitine; Hypertension; NADPH Oxidases; NF-kappa B; Oxidative Stress; Protein Kinase C | 2017 |
TMEM16A Contributes to Endothelial Dysfunction by Facilitating Nox2 NADPH Oxidase-Derived Reactive Oxygen Species Generation in Hypertension.
Topics: Angiotensin II; Animals; Anoctamin-1; Blood Pressure; Chloride Channels; Endothelial Cells; Endothelium, Vascular; Hypertension; Membrane Glycoproteins; Mice; Mice, Knockout; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidases; Phosphorylation; Proteasome Endopeptidase Complex; Reactive Oxygen Species | 2017 |
miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling.
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiovascular Diseases; Endothelial Cells; Extracellular Matrix; Hypertension; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Nitric Oxide; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Vascular Stiffness | 2017 |
γδ T Cells Mediate Angiotensin II-Induced Hypertension and Vascular Injury.
Topics: Angiotensin II; Animals; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes; Vascular System Injuries | 2017 |
ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.
Topics: Angiotensin II; Animals; Aorta; Apelin Receptors; Arterial Pressure; Cardiotonic Agents; Constriction; Disease Models, Animal; Fibrosis; Forkhead Box Protein M1; Gene Expression Regulation; Heart Failure; HEK293 Cells; Humans; Hypertension; Hypertrophy, Left Ventricular; Infusions, Subcutaneous; Ligands; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardium; Peptide Hormones; Peptidyl-Dipeptidase A; Signal Transduction; Transfection; Ventricular Dysfunction, Left; Ventricular Function, Left | 2017 |
Treatment with salvianolic acid B restores endothelial function in angiotensin II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Benzofurans; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Treatment Outcome | 2017 |
Brain Renin-Angiotensin System: Does It Exist?
Topics: Amides; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Desoxycorticosterone Acetate; Disease Models, Animal; Fumarates; Hypertension; Mice; Mice, Knockout; Random Allocation; Rats; Rats, Inbred SHR; Reference Values; Renin-Angiotensin System | 2017 |
Resistance to hypertension mediated by intercalated cells of the collecting duct.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Hypertension; Kidney Tubules, Collecting; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1 | 2017 |
2-Methoxyestradiol Reduces Angiotensin II-Induced Hypertension and Renal Dysfunction in Ovariectomized Female and Intact Male Mice.
Topics: 2-Methoxyestradiol; Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Cytochrome P-450 CYP1B1; Disease Models, Animal; Estradiol; Female; Hypertension; Kidney Diseases; Kidney Function Tests; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovariectomy; Random Allocation; Reactive Oxygen Species; Sensitivity and Specificity; Sex Factors | 2017 |
Inhibitory effects of losartan and azelnidipine on augmentation of blood pressure variability induced by angiotensin II in rats.
Topics: Angiotensin II; Animals; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Hypertension; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Time Factors | 2017 |
A novel mechanism of angiotensin II-regulated placental vascular tone in the development of hypertension in preeclampsia.
Topics: Angiotensin II; Animals; Catecholamines; Female; Hemodynamics; Humans; Hypertension; Placenta; Placental Circulation; Pre-Eclampsia; Pregnancy; Receptors, Adrenergic; Renin-Angiotensin System; Sheep; Vasoconstriction | 2017 |
Activation of AMP-activated protein kinase by metformin ablates angiotensin II-induced endoplasmic reticulum stress and hypertension in mice in vivo.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Humans; Hypertension; Metformin; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Structure-Activity Relationship | 2017 |
Catechol-O-Methyltransferase Deficiency Leads to Hypersensitivity of the Pressor Response Against Angiotensin II.
Topics: Angiotensin II; Animals; Catechol O-Methyltransferase; Drug Hypersensitivity; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pioglitazone; PPAR gamma; Pre-Eclampsia; Pregnancy; Pregnancy, Animal; Receptor, Angiotensin, Type 1; Reference Values; Thiazolidinediones; Vasoconstrictor Agents | 2017 |
Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway.
Topics: Angiotensin II; Animals; Aorta; Gene Expression; Humans; Hypertension; Mice, Inbred C57BL; Rats, Inbred WKY; Receptors, Notch; RNA, Messenger; Signal Transduction; Soluble Guanylyl Cyclase | 2017 |
Angiotensin II/Angiotensin II Receptor Blockade Affects Osteoporosis via the AT1/AT2-Mediated cAMP-Dependent PKA Pathway.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; Hypertension; Mice; Mice, Inbred C57BL; Osteoporosis; Receptors, Angiotensin | 2017 |
Sodium butyrate suppresses angiotensin II-induced hypertension by inhibition of renal (pro)renin receptor and intrarenal renin-angiotensin system.
Topics: Angiotensin II; Animals; Butyric Acid; Hypertension; Prorenin Receptor; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Renin-Angiotensin System | 2017 |
Clinical Relevance and Role of Neuronal AT
Topics: ADAM17 Protein; Adult; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Cells, Cultured; Female; Humans; Hypertension; Hypothalamus; Male; Mice; Mice, Knockout; Mice, Transgenic; Neurons; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1 | 2017 |
Angiotensin II induces calcium/calcineurin signaling and podocyte injury by downregulating microRNA-30 family members.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcineurin; Calcium; Calcium Signaling; Cells, Cultured; Down-Regulation; Humans; Hypertension; Kidney Diseases; Kidney Glomerulus; Losartan; Male; Mice, Inbred C57BL; MicroRNAs; Podocytes | 2017 |
Central TrkB blockade attenuates ICV angiotensin II-hypertension and sympathetic nerve activity in male Sprague-Dawley rats.
Topics: Angiotensin II; Animals; Azepines; Baroreflex; Benzamides; Blood Pressure; Body Weight; Cardiovascular Agents; Defecation; Drinking; Heart Rate; Hypertension; Kidney; Male; Organ Size; Rats, Sprague-Dawley; Receptor, trkB; Sympathetic Nervous System; Urination | 2017 |
Chronic administration of sodium nitrite prevents hypertension and protects arterial endothelial function by reducing oxidative stress in angiotensin II-infused mice.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta, Thoracic; Arterial Pressure; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidase 4; Nitric Oxide; Oxidative Stress; Renal Artery; Sodium Nitrite; Tyrosine; Vasodilation | 2018 |
Enhancement of intrarenal plasma membrane calcium pump isoform 1 expression in chronic angiotensin II-infused mice.
Topics: Angiotensin II; Animals; Gene Expression Regulation; Hypertension; Male; Mice; Mice, Inbred C57BL; Nephrectomy; Plasma Membrane Calcium-Transporting ATPases; Ureteral Obstruction | 2017 |
Tail-Cuff Technique and Its Influence on Central Blood Pressure in the Mouse.
Topics: Angiotensin II; Animals; Behavior, Animal; Blood Pressure; Blood Pressure Determination; Body Temperature Regulation; Disease Models, Animal; Female; Habituation, Psychophysiologic; Handling, Psychological; Heart Rate; Humans; Hypertension; Male; Mice, Inbred C57BL; Plethysmography; Predictive Value of Tests; Regional Blood Flow; Reproducibility of Results; Restraint, Physical; Stress, Psychological; Tail; Telemetry; Time Factors | 2017 |
Vaccarin administration ameliorates hypertension and cardiovascular remodeling in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Flavonoids; Gene Expression Regulation; Glycosides; Hypertension; Male; Norepinephrine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin; Ventricular Remodeling | 2018 |
Brain Transforming Growth Factor-β Resists Hypertension Via Regulating Microglial Activation.
Topics: Adoptive Transfer; Angiotensin II; Animals; Blood Pressure; Brain; CD11b Antigen; Diphtheria Toxin; Flow Cytometry; Heparin-binding EGF-like Growth Factor; Hypertension; Immunohistochemistry; Kidney; Male; Mice; Mice, Inbred C57BL; Microglia; Norepinephrine; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sympathetic Nervous System; Transcriptome; Transforming Growth Factor beta1; Vasoconstrictor Agents | 2017 |
Positive correlation between blood pressure or heart rate and chymase-dependent angiotensin II-forming activity in circulating mononuclear leukocytes measured by new ELISA.
Topics: Adult; Age Factors; Aged; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Chymases; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Heart Rate; Humans; Hypertension; Leukocytes, Mononuclear; Male; Middle Aged; Natriuretic Peptide, Brain; Sex Factors | 2018 |
Role of the histone deacetylase inhibitor valproic acid in high-fat diet-induced hypertension via inhibition of HDAC1/angiotensin II axis.
Topics: Angiotensin II; Animals; Blotting, Western; Diet, High-Fat; Disease Models, Animal; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Hypertension; Male; Mice; Mice, Inbred C57BL; Valproic Acid | 2017 |
Differential responses of mesenteric arterial bed to vasoactive substances in L-NAME-induced preeclampsia: Role of oxidative stress and endothelial dysfunction.
Topics: Acetylcholine; Angiotensin II; Animals; Arginine; Blood Pressure; Enzyme Inhibitors; Female; Fetal Growth Retardation; Glutathione Peroxidase; Hypertension; Malondialdehyde; Mesentery; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Oxidative Stress; Phenylephrine; Placenta; Pre-Eclampsia; Pregnancy; Protein Carbonylation; Rats; Superoxide Dismutase; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2018 |
Prenatal exposure to angiotensin II increases blood pressure and decreases salt sensitivity in rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Female; Heart Ventricles; Hypertension; Kidney; Male; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Vasoconstrictor Agents | 2017 |
Nitroxyl Anion Mediates Relaxation in Mesenteric Arteries from Angiotensin II Hypertensive Mice.
Topics: 4-Aminopyridine; Acetylcholine; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; Nitrogen Oxides; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2017 |
Activation of Transient Receptor Potential Melastatin Subtype 8 Attenuates Cold-Induced Hypertension Through Ameliorating Vascular Mitochondrial Dysfunction.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Calcium; Cell Respiration; Cells, Cultured; Cold Temperature; Dietary Supplements; Homeostasis; Hypertension; Male; Menthol; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Muscle; Mitochondrial Diseases; Muscle, Smooth, Vascular; Reactive Oxygen Species; rho-Associated Kinases; TRPM Cation Channels; Vasoconstriction | 2017 |
Effect of uric acid on inflammatory COX-2 and ROS pathways in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Disease Models, Animal; Humans; Hypertension; Inflammation; Losartan; Muscle, Smooth, Vascular; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; Receptor Protein-Tyrosine Kinases; Signal Transduction; Superoxides; Uric Acid | 2017 |
Accumulation of Smooth Muscle 22α Protein Accelerates Senescence of Vascular Smooth Muscle Cells via Stabilization of p53 In Vitro and In Vivo.
Topics: Actin Cytoskeleton; Angiotensin II; Animals; Aorta; Cellular Senescence; Hypertension; Mice; Microfilament Proteins; Models, Animal; Muscle Proteins; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53; Ubiquitination; Up-Regulation | 2017 |
The valosin-containing protein is a novel repressor of cardiomyocyte hypertrophy induced by pressure overload.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Cerebrovascular Disorders; Echocardiography; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Male; Mechanistic Target of Rapamycin Complex 1; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Pressure; Primary Cell Culture; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Valosin Containing Protein; Ventricular Remodeling | 2017 |
Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Epithelial Sodium Channels; Genetic Predisposition to Disease; Hypertension; Kidney Tubules, Collecting; Mice, Inbred C57BL; Mice, Knockout; Natriuresis; Phenotype; Proteinuria; Proton-Translocating ATPases; Receptors, Cell Surface; Renal Elimination; Renin; Sodium; Sodium Chloride, Dietary; Time Factors | 2017 |
Intranasal vaccination against angiotensin II type 1 receptor and pneumococcal surface protein A attenuates hypertension and pneumococcal infection in rodents.
Topics: Administration, Intranasal; Angiotensin II; Animals; Antibodies, Bacterial; Bacterial Proteins; Blood Pressure; Female; Hypertension; Immunization, Passive; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Pneumococcal Infections; Pneumococcal Vaccines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Streptococcus pneumoniae; Vaccination | 2018 |
Evidence for Prohypertensive, Proinflammatory Effect of Interleukin-10 During Chronic High Salt Intake in the Condition of Elevated Angiotensin II Level.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Interleukin-10; Kidney; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Sodium Chloride, Dietary | 2017 |
Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis.
Topics: Acetylation; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Collagen Type I; Collagen Type III; Disease Models, Animal; Disease Progression; Fibrosis; Genetic Predisposition to Disease; Hypertension; Mice, 129 Strain; Mice, Knockout; Mitochondria, Heart; Mitophagy; Myocardium; Neovascularization, Physiologic; Oxidative Stress; Phenotype; Protein Kinases; Signal Transduction; Sirtuin 3; Time Factors; Tissue Culture Techniques; Ubiquitin-Protein Ligases; Ventricular Remodeling | 2017 |
Acute simvastatin treatment restores cerebral functional capillary density and attenuates angiotensin II-induced microcirculatory changes in a model of primary hypertension.
Topics: Angiotensin II; Animals; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Male; Microcirculation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Simvastatin | 2017 |
Nocturnal diastolic blood pressure decline is associated with higher 25-hydroxyvitamin D level and standing plasma renin activity in a hypertensive population.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Mass Index; Circadian Rhythm; Cross-Sectional Studies; Diastole; Female; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Renin-Angiotensin System; Vitamin D; Vitamin D Deficiency | 2017 |
Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II.
Topics: Aldosterone; Amiloride; Angiotensin II; Animals; Blood Pressure; Diuretics; Epithelial Sodium Channels; Gene Knock-In Techniques; Hypertension; Male; Mice; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Sodium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 3 | 2018 |
Angiotensin II type 1a receptor-deficient mice develop angiotensin II-induced oxidative stress and DNA damage without blood pressure increase.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; DNA Damage; Hypertension; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1 | 2017 |
EPA:DHA 6:1 prevents angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase- and COX-derived oxidative stress.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Drug Evaluation, Preclinical; Endothelium, Vascular; Fatty Acids, Omega-3; Hypertension; Male; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Random Allocation; Rats, Wistar | 2017 |
MAPK activation patterns of AT1R and CB1R in SHR versus Wistar astrocytes: Evidence of CB1R hypofunction and crosstalk between AT1R and CB1R.
Topics: Angiotensin II; Animals; Arachidonic Acids; Astrocytes; Blood Pressure; Cannabinoids; Disease Models, Animal; Humans; Hypertension; MAP Kinase Kinase 1; Phosphorylation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Cannabinoid | 2017 |
Treatment of hypertension by increasing impaired endothelial TRPV4-KCa2.3 interaction.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Mutagenesis; Nitroprusside; Plasmids; Potassium Channels, Calcium-Activated; TRPV Cation Channels; Vasodilation | 2017 |
Endothelial
Topics: Albumins; Angiotensin II; Animals; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Cell Differentiation; Crosses, Genetic; Disease Progression; Epithelial Cells; Gene Deletion; Gene Expression Regulation; Glomerulosclerosis, Focal Segmental; Hypertension; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Podocytes; Telemetry | 2017 |
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Male; NF-kappa B; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Extracts; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Tribulus | 2017 |
Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm.
Topics: ADAM17 Protein; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; ErbB Receptors; Hypertension; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Protein-Lysine 6-Oxidase; Receptor Activity-Modifying Proteins; Signal Transduction | 2017 |
Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation.
Topics: Aging; Angiotensin II; Animals; Aortic Valve Stenosis; Cells, Cultured; Chemokine CCL2; Fibroblasts; Fibrosis; Humans; Hypertension; Intercellular Adhesion Molecule-1; Intercellular Signaling Peptides and Proteins; Interleukin-1beta; Macrophages; Mice; Myocardium | 2018 |
Interleukin 22 Promotes Blood Pressure Elevation and Endothelial Dysfunction in Angiotensin II-Treated Mice.
Topics: Adult; Aged; Angiotensin II; Animals; Antibodies, Monoclonal; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation Mediators; Interleukin-22; Interleukins; Male; Mice, Inbred C57BL; Middle Aged; Nitric Oxide Synthase Type III; Phosphorylation; Recombinant Proteins; STAT3 Transcription Factor; Time Factors; Vasodilation; Vasodilator Agents | 2017 |
Apelin Is a Negative Regulator of Angiotensin II-Mediated Adverse Myocardial Remodeling and Dysfunction.
Topics: Angiotensin II; Animals; Animals, Newborn; Apelin; Apoptosis; Cells, Cultured; Disease Models, Animal; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Knockout; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Ventricular Remodeling | 2017 |
Endothelial Mineralocorticoid Receptor Mediates Parenchymal Arteriole and Posterior Cerebral Artery Remodeling During Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Hypertension; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Posterior Cerebral Artery; Receptors, Mineralocorticoid; Vascular Remodeling | 2017 |
NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension.
Topics: Angiotensin II; Animals; Caspase 1; Cell Proliferation; Curcumin; Gene Expression Regulation; Humans; Hypertension; Inflammasomes; Muscle, Smooth, Vascular; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenotype; Rats; Rats, Inbred SHR; Signal Transduction | 2017 |
Topics: Actins; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Movement; Cells, Cultured; Disease Models, Animal; Genotype; Hypertension; Male; Mice; Mutation, Missense; Myosin Heavy Chains; Nephrectomy; Nonmuscle Myosin Type IIA; Podocytes; Primary Cell Culture; Renal Insufficiency, Chronic; Sodium Chloride, Dietary; Stress Fibers; Tetrazoles | 2018 |
Matrix metalloproteinase-2 knockout prevents angiotensin II-induced vascular injury.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelium, Vascular; Hypertension; Male; Matrix Metalloproteinase 2; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Oxidative Stress; Vascular System Injuries | 2017 |
Differential Expression of Hypertensive Phenotypes in BXD Mouse Strains in Response to Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Fibrosis; Heart Diseases; Hypertension; Inflammation; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Phenotype; Species Specificity; Transforming Growth Factor beta; Vasoconstrictor Agents | 2017 |
Sex differences in maternal gestational hypertension-induced sensitization of angiotensin II hypertension in rat offspring: the protective effect of estrogen.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression Regulation; Gestational Age; Hypertension; Hypertension, Pregnancy-Induced; Male; NADPH Oxidase 2; Orchiectomy; Ovariectomy; Pregnancy; Prenatal Exposure Delayed Effects; Protective Factors; Rats, Sprague-Dawley; Renin-Angiotensin System; Risk Factors; Sex Factors | 2018 |
Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.
Topics: Angiotensin II; Animals; Biomarkers; Blood Glucose; Blood Pressure; Cardiomegaly; Diet, High-Fat; Disease Models, Animal; Female; Fibrosis; Genetic Predisposition to Disease; Heart Rate; Hypertension; Male; Metabolic Syndrome; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NADPH Oxidase 4; Phenotype; Reactive Oxygen Species; Time Factors; Triglycerides; Ventricular Remodeling | 2018 |
Adiponectin and its receptors are involved in hypertensive vascular injury.
Topics: Adiponectin; Angiotensin II; Animals; Cell Line; Gene Expression Regulation; Hypertension; Male; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, Adiponectin; Vascular Remodeling; Vascular System Injuries | 2018 |
Deletion of protein kinase B2 preserves cardiac function by blocking interleukin-6-mediated injury and restores blood pressure during angiotensin II/high-salt-diet-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Movement; Chemokine CCL2; Fibrosis; Gene Expression; Hypertension; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-akt; Sodium Chloride, Dietary; Stroke Volume; Vasoconstrictor Agents; Ventricular Function, Left | 2018 |
Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats.
Topics: Aldosterone; Angiotensin II; Animals; Arterial Pressure; Brain; Cardenolides; Cardiovascular System; Cytochrome P-450 CYP11B2; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Male; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Renin-Angiotensin System; Saponins; Sodium Chloride, Dietary; Sodium-Calcium Exchanger; Sympathetic Nervous System; Time Factors | 2018 |
Nitric oxide production by glomerular podocytes.
Topics: Angiotensin II; Animals; Calcium Signaling; Glomerular Filtration Barrier; Hydrogen Peroxide; Hypertension; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Podocytes; Rats, Inbred Dahl; Sodium Chloride, Dietary | 2018 |
Regulation of angiotensin II actions by enhancers and super-enhancers in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Atherosclerosis; Azepines; Cells, Cultured; Gene Expression Regulation; Histones; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; RNA, Long Noncoding; Signal Transduction; Triazoles | 2017 |
Gallic Acid Reduces Blood Pressure and Attenuates Oxidative Stress and Cardiac Hypertrophy in Spontaneously Hypertensive Rats.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Cardiomegaly; Gallic Acid; GATA4 Transcription Factor; Gene Expression Regulation; Heart; Homeobox Protein Nkx-2.5; Humans; Hypertension; Male; NADPH Oxidase 2; Oxidative Stress; Rats; Rats, Inbred SHR | 2017 |
Identifications of potential therapeutic targets and drugs in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Gene Expression Profiling; Gene Ontology; Hypertension; Mice; MicroRNAs; Molecular Targeted Therapy | 2017 |
Burst patterning of hypothalamic paraventricular nucleus-driven sympathetic nerve activity in ANG II-salt hypertension.
Topics: Angiotensin II; Animals; Arterial Pressure; Baroreflex; Disease Models, Animal; GABA-A Receptor Agonists; Heart; Heart Rate; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Periodicity; Phrenic Nerve; Rats, Sprague-Dawley; Respiratory Rate; Sodium Chloride, Dietary; Splanchnic Nerves; Sympathetic Nervous System; Time Factors | 2018 |
Renal sympathetic denervation lowers arterial pressure in canines with obesity-induced hypertension by regulating GAD65 and AT
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypertension; Male; Medulla Oblongata; Obesity; Receptor, Angiotensin, Type 1; Renal Artery; RNA, Messenger; Sympathectomy | 2018 |
Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Dose-Response Relationship, Drug; Female; Heat-Shock Proteins; HEK293 Cells; Humans; Hypertension; Polycomb Repressive Complex 1; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, IGF Type 2; Sumoylation; Transcription Factors; Up-Regulation | 2018 |
Letter by Campbell Regarding Article, "γδ T Cells Mediate Angiotensin II-Induced Hypertension and Vascular Injury".
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; T-Lymphocytes; Vascular System Injuries | 2017 |
Response by Caillon et al to Letter Regarding Article, "γδ T Cells Mediate Angiotensin II-Induced Hypertension and Vascular Injury".
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; T-Lymphocytes; Vascular System Injuries | 2017 |
Contractile Responses in Spontaneously Hypertensive Rats after Transient Middle Cerebral Artery Occlusion.
Topics: Angiotensin II; Animals; Blood Pressure; Carbachol; Endothelin-1; Hypertension; Infarction, Middle Cerebral Artery; Male; Middle Cerebral Artery; Potassium; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation; Viper Venoms | 2018 |
Association of circulating progenitor cells with angiotensin II in newly diagnosed hypertensive patients.
Topics: Aged; Angiotensin II; Antigens, CD34; Case-Control Studies; Endothelial Progenitor Cells; Female; Humans; Hypertension; Male; Middle Aged; Vascular Endothelial Growth Factor Receptor-2 | 2017 |
Loss of Vascular Myogenic Tone in miR-143/145 Knockout Mice Is Associated With Hypertension-Induced Vascular Lesions in Small Mesenteric Arteries.
Topics: Actin Cytoskeleton; Angiotensin II; Animals; Arterial Pressure; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Elastic Tissue; Female; Fibrosis; Gene Knockout Techniques; Hyperplasia; Hypertension; Male; Mesenteric Arteries; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Neointima; Vascular Remodeling; Vascular Resistance; Vasoconstriction | 2018 |
Losartan suppresses the kainate-induced changes of angiotensin AT
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Blood Pressure; Comorbidity; Disease Models, Animal; Epilepsy; Gene Expression; Hippocampus; Hypertension; Kainic Acid; Limbic System; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2018 |
Temporal changes in cardiac oxidative stress, inflammation and remodeling induced by exercise in hypertension: Role for local angiotensin II reduction.
Topics: Angiotensin II; Animals; Hypertension; Inflammation; Male; Myocardium; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Ventricular Remodeling | 2017 |
Alteration of serum immunoglobins, C-reactive protein, vitamin D, and electrolyte by atenolol and amlodipine in stress-induced hypertensive rats.
Topics: Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Atenolol; C-Reactive Protein; Calcium; Electrolytes; Female; Hypertension; Immunoglobulin G; Immunoglobulin M; Male; Potassium; Rats, Wistar; Sodium; Stress, Physiological; Vitamin D | 2018 |
NLRP3 Gene Deletion Attenuates Angiotensin II-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Vascular Remodeling.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Gene Deletion; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NLR Family, Pyrin Domain-Containing 3 Protein; Vascular Remodeling | 2017 |
Gallic acid attenuates calcium calmodulin-dependent kinase II-induced apoptosis in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Atrial Natriuretic Factor; bcl-2-Associated X Protein; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiotonic Agents; Caspase 3; Cell Line; Gallic Acid; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Isoenzymes; Male; Myocytes, Cardiac; Natriuretic Peptide, Brain; Nitric Oxide Synthase; p300-CBP Transcription Factors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Tumor Suppressor Protein p53 | 2018 |
The novel organic mononitrate NDHP attenuates hypertension and endothelial dysfunction in hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Nitro Compounds; Oxidative Stress; Rats; Rats, Inbred Dahl; Xanthine Dehydrogenase | 2018 |
Cellular mechanisms of metabolic syndrome-related atrial decompensation in a rat model of HFpEF.
Topics: Angiotensin II; Animals; Atrial Remodeling; Calcium; Calcium Signaling; Cell Nucleus; Cytosol; Disease Models, Animal; Excitation Contraction Coupling; Heart Atria; Heart Failure; Heart Ventricles; Hypertension; Metabolic Syndrome; Myocytes, Cardiac; Rats; Sarcoplasmic Reticulum; Stroke Volume | 2018 |
Modulating Role of Ang1-7 in Control of Blood Pressure and Renal Function in AngII-infused Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Male; Natriuresis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Urodynamics | 2018 |
Brain Cytosolic Phospholipase A2α Mediates Angiotensin II-Induced Hypertension and Reactive Oxygen Species Production in Male Mice.
Topics: Angiotensin II; Animals; Brain; Collagen; Endoplasmic Reticulum Stress; Group IV Phospholipases A2; Hypertension; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Reactive Oxygen Species | 2018 |
Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Hypertension; Infusions, Intraventricular; Male; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 4; Neurons; Promoter Regions, Genetic; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Signal Transduction; Synapsins; Up-Regulation; Vacuolar Proton-Translocating ATPases | 2018 |
Homeostatic Response of Mouse
Topics: Alleles; Angiotensin II; Animals; Animals, Genetically Modified; Clustered Regularly Interspaced Short Palindromic Repeats; Enhancer Elements, Genetic; Female; Homeostasis; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Transcription, Genetic | 2018 |
Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice: Techniques and Pitfalls.
Topics: Angiotensin II; Animals; Carotid Arteries; Cell Adhesion; Hypertension; Leukocyte Rolling; Leukocytes; Male; Mice; Mice, Transgenic | 2018 |
Maternal high-fat diet acts on the brain to induce baroreflex dysfunction and sensitization of angiotensin II-induced hypertension in adult offspring.
Topics: Angiotensin II; Animal Nutritional Physiological Phenomena; Animals; Baroreflex; Blood Pressure; Brain; Cytokines; Diet, High-Fat; Disease Models, Animal; Female; Heart; Hypertension; Inflammation Mediators; Male; Maternal Nutritional Physiological Phenomena; NADPH Oxidases; Nutritional Status; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstriction | 2018 |
Myeloid CD11c
Topics: Angiotensin II; Animals; Antigen-Presenting Cells; Blood Pressure; CD11c Antigen; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Inflammation; Ion Transport; Mice; Mice, Transgenic; Myeloid Cells; Sodium Chloride, Dietary | 2018 |
Role of afferent and efferent renal nerves in the development of AngII-salt hypertension in rats.
Topics: Afferent Pathways; Angiotensin II; Animals; Efferent Pathways; Hypertension; Kidney; Male; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Salt Stress; Sodium Chloride, Dietary | 2018 |
Osteoglycin attenuates cardiac fibrosis by suppressing cardiac myofibroblast proliferation and migration through antagonizing lysophosphatidic acid 3/matrix metalloproteinase 2/epidermal growth factor receptor signalling.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; ErbB Receptors; Fibrosis; Hypertension; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Myofibroblasts; Receptor Cross-Talk; Receptors, Lysophosphatidic Acid; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Ventricular Remodeling | 2018 |
Deficiency of Complement C3a and C5a Receptors Prevents Angiotensin II-Induced Hypertension via Regulatory T Cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Hypertension; Male; Mice; Mice, Inbred BALB C; Receptor, Anaphylatoxin C5a; Receptors, Complement 3b; T-Lymphocytes, Regulatory | 2018 |
Angiotensin II-induced Hypertension is Reduced by Deficiency of P-selectin Glycoprotein Ligand-1.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Interleukin-17; Membrane Glycoproteins; Mice; Mice, Knockout; Vasoconstrictor Agents | 2018 |
Hypertension: Role of C3aR and C5aR in T
Topics: Angiotensin II; Complement C3a; Humans; Hypertension; Receptor, Anaphylatoxin C5a; T-Lymphocytes, Regulatory | 2018 |
Transplantation of skin mesenchymal stem cells attenuated AngII-induced hypertension and vascular injury.
Topics: Angiotensin II; Animals; Cell Differentiation; Hypertension; Macrophages; Mesenchymal Stem Cell Transplantation; Mice; Mice, Inbred C57BL; Th17 Cells; Vascular System Injuries | 2018 |
Differential effect of angiotensin II and blood pressure on hippocampal inflammation in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Hippocampus; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Random Allocation | 2018 |
Assessing the role of hypothalamic microglia and blood vessel disruption in the development of angiotensin II-dependent hypertension in Cyp1a1-Ren2 rats.
Topics: Angiotensin II; Animals; Blood Vessels; Blood-Brain Barrier; Calcium-Binding Proteins; Cytochrome P-450 CYP1A1; Hypertension; Hypothalamus; Male; Microfilament Proteins; Microglia; Rats; Renin | 2018 |
Differential effects of long-term slow-pressor and subpressor angiotensin II on contractile and relaxant reactivity of resistance versus conductance arteries.
Topics: Angiotensin II; Animals; Arteries; Hypertension; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2018 |
Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4-NKX2-5 Interaction.
Topics: Angiotensin II; Animals; GATA4 Transcription Factor; Gene Expression Regulation; Homeobox Protein Nkx-2.5; Hypertension; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Phosphorylation; Protein Interaction Domains and Motifs; Rats, Sprague-Dawley; Reperfusion Injury; Small Molecule Libraries | 2018 |
Effects and Mechanism of SO2 Inhalation on Rat Myocardial Collagen Fibers.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weights and Measures; Collagen; Heart; Heart Ventricles; Hydroxyproline; Hypertension; Losartan; Male; Myocardium; Myocytes, Cardiac; Rats; Sulfur Dioxide; Ventricular Remodeling | 2018 |
Co-administration of resveratrol with doxorubicin in young mice attenuates detrimental late-occurring cardiovascular changes.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Blood Pressure; Cardiotoxicity; Disease Models, Animal; Doxorubicin; Enzyme Activation; Heart Diseases; Hypertension; Male; Mice, Inbred C57BL; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Signal Transduction; Time Factors; Ventricular Remodeling | 2018 |
Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acids; Arrhythmias, Cardiac; Blood Pressure; Hypertension; Rats; Rats, Sprague-Dawley; Rats, Transgenic | 2018 |
Complementing T Regulatory Cells to Combat Hypertension.
Topics: Angiotensin II; Complement C3a; Humans; Hypertension; Receptor, Anaphylatoxin C5a; T-Lymphocytes, Regulatory | 2018 |
Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium Signaling; Cell Line; Disease Models, Animal; Hypertension; Male; Mesenteric Arteries; Mice, Knockout, ApoE; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphorylation; Receptor, Angiotensin, Type 1; RGS Proteins; Vasoconstriction; Vasodilation | 2018 |
Angiotensin II Short-Loop Feedback: Is There a Role of Ang II for the Regulation of the Renin System In Vivo?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Female; Hypertension; Immunohistochemistry; Male; Mice; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2018 |
MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 5; Gene Expression Regulation; Humans; Hypertension; Mice, Transgenic; MicroRNAs; Myocytes, Cardiac; Signal Transduction | 2018 |
Sulfatase 1 mediates the attenuation of Ang II-induced hypertensive effects by CCL5 in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Animals; Antihypertensive Agents; Arachidonate 12-Lipoxygenase; Chemokine CCL5; Down-Regulation; Endothelin-1; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Sulfotransferases; Up-Regulation | 2018 |
Angiotensin II Promotes K
Topics: Angiotensin II; Animals; Blotting, Western; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; HSP90 Heat-Shock Proteins; Hypertension; KCNQ Potassium Channels; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Wistar; Vasodilation | 2018 |
Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Female; Humans; Hypertension; Male; Middle Aged; Rats; Rats, Wistar; Renin-Angiotensin System; Sex Factors; Zona Glomerulosa | 2018 |
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
Topics: Adoptive Transfer; Angiotensin II; Animals; CD4-Positive T-Lymphocytes; Female; Forkhead Transcription Factors; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Cardiovascular; Myocardium; NADPH Oxidase 2; NF-kappa B; T-Lymphocytes, Regulatory; Vascular Remodeling | 2018 |
Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Line; Disease Models, Animal; Female; Half-Life; Humans; Hypertension; Immunoglobulin Fc Fragments; Mice; Mice, Inbred BALB C; Peptidyl-Dipeptidase A; Recombinant Fusion Proteins; Renin; Renin-Angiotensin System; Treatment Outcome | 2018 |
FGF21 Prevents Angiotensin II-Induced Hypertension and Vascular Dysfunction by Activation of ACE2/Angiotensin-(1-7) Axis in Mice.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiovascular System; Fibroblast Growth Factors; Hypertension; Kidney; Loss of Function Mutation; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
Egg White-Derived Antihypertensive Peptide IRW (Ile-Arg-Trp) Inhibits Angiotensin II-Stimulated Migration of Vascular Smooth Muscle Cells via Angiotensin Type I Receptor.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Movement; Egg White; Humans; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptides; Rats; Receptor, Angiotensin, Type 1; Signal Transduction | 2018 |
Effect of pioglitazone on vasopressor responses to adrenergic agonists and angiotensin II in diabetic and non-diabetic spontaneously hypertensive rats.
Topics: Adrenergic Agonists; Angiotensin II; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hemodynamics; Hypertension; Hypoglycemic Agents; Pioglitazone; Rats; Rats, Inbred SHR; Vasoconstrictor Agents | 2018 |
Link between FGF21 and blood pressure.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Fibroblast Growth Factors; Humans; Hypertension; Mice; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
Hesperidin Suppresses Renin-Angiotensin System Mediated NOX2 Over-Expression and Sympathoexcitation in 2K-1C Hypertensive Rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Citrus; Gene Expression; Hesperidin; Hypertension; In Vitro Techniques; Kidney; Male; NADPH Oxidase 2; Oxidative Stress; Peptidyl-Dipeptidase A; Phytotherapy; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathomimetics | 2018 |
FGF21 ACEs hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Fibroblast Growth Factors; Hypertension; Mice; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide.
Topics: Aged; Angiotensin II; Animals; Blood Pressure; Case-Control Studies; Cell Communication; Cell Differentiation; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Endothelial Cells; Female; Humans; Hydrogen Peroxide; Hypertension; Interleukin-6; Male; Mechanotransduction, Cellular; Mice, Inbred C57BL; Middle Aged; Monocytes; Nitric Oxide; Phenotype; STAT3 Transcription Factor; Stress, Mechanical | 2018 |
The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Genetic Predisposition to Disease; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phenotype; Receptors, G-Protein-Coupled; Ventricular Dysfunction, Left; Ventricular Function, Left | 2018 |
Angiotensin II-Induced End-Organ Damage in Mice Is Attenuated by Human Exosomes and by an Exosomal Y RNA Fragment.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Exosomes; Humans; Hypertension; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; RNA | 2018 |
Adopting an Orphan: How Could GRP35 Contribute to Angiotensin II-Dependent Hypertension?
Topics: Angiotensin II; Animals; Blood Pressure; Heart Diseases; Hypertension; Mice | 2018 |
Role of Cryptochrome-1 and Cryptochrome-2 in Aldosterone-Producing Adenomas and Adrenocortical Cells.
Topics: Adenoma; Aldosterone; Angiotensin II; Animals; Cell Line, Tumor; Cryptochromes; Gene Expression Regulation, Neoplastic; Humans; Hyperaldosteronism; Hypertension; Mice; Multienzyme Complexes; Progesterone Reductase; Steroid Isomerases | 2018 |
Vascular type 1 angiotensin receptors control blood pressure by augmenting peripheral vascular resistance in female mice.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Kidney; Male; Mice, Transgenic; Myocytes, Smooth Muscle; Natriuresis; Receptor, Angiotensin, Type 1; Sex Factors; Sodium; Vascular Resistance; Vasoconstrictor Agents | 2018 |
α2δ-1 Is Essential for Sympathetic Output and NMDA Receptor Activity Potentiated by Angiotensin II in the Hypothalamus.
Topics: Angiotensin II; Animals; Calcium Channels; Female; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Renin-Angiotensin System; Sympathetic Nervous System | 2018 |
Intrarenal ghrelin receptor inhibition ameliorates angiotensin II-dependent hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Glomerular Filtration Rate; Hypertension; Kidney; Rats, Sprague-Dawley; Receptors, Ghrelin; Renal Circulation; Sodium | 2018 |
IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
Topics: Aging; Angiotensin II; Animals; Cerebral Arteries; Cerebral Hemorrhage; Disease Models, Animal; Hypertension; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL | 2019 |
Drebrin regulates angiotensin II-induced aortic remodelling.
Topics: Angiotensin II; Animals; Aorta; Aortic Diseases; Arterial Pressure; Cell Proliferation; Disease Models, Animal; Extracellular Matrix; HEK293 Cells; Humans; Hypertension; Inflammation Mediators; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Neuropeptides; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling | 2018 |
Beneficial Morphofunctional Changes Promoted by Sildenafil in Resistance Vessels in the Angiotensin II-Induced Hypertension Model.
Topics: Angiotensin II; Animals; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Phosphodiesterase 5 Inhibitors; Reactive Oxygen Species; Sildenafil Citrate | 2018 |
CD1d-dependent natural killer T cells attenuate angiotensin II-induced cardiac remodelling via IL-10 signalling in mice.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antigens, CD1d; Cardiomegaly; Cells, Cultured; Coculture Techniques; Dendritic Cells; Disease Models, Animal; Fibrosis; Galactosylceramides; Hypertension; Inflammation Mediators; Interleukin-10; Male; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Natural Killer T-Cells; NF-kappa B; Signal Transduction; STAT3 Transcription Factor; Transforming Growth Factor beta1; Ventricular Remodeling | 2019 |
Median preoptic nucleus excitatory neurotransmitters in the maintenance of hypertensive state.
Topics: Angiotensin II; Animals; Disease Models, Animal; Glutamic Acid; Hypertension; Male; Preoptic Area; Rats, Inbred SHR; Rats, Wistar; Receptors, Neurotransmitter | 2018 |
Benzbromarone Attenuates Oxidative Stress in Angiotensin II- and Salt-Induced Hypertensive Model Rats.
Topics: Angiotensin II; Animals; Antioxidants; Benzbromarone; Disease Models, Animal; Hypertension; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sodium Chloride, Dietary | 2018 |
Eriobotrya japonica ameliorates cardiac hypertrophy in H9c2 cardiomyoblast and in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Drugs, Chinese Herbal; Echocardiography; Eriobotrya; Heart; Hypertension; Male; Myocytes, Cardiac; Phytotherapy; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2018 |
Analysis of Genes Related to Angiotensin II-Induced Arterial Injury Using a Time Series Microarray.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cluster Analysis; Collagen Type I; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Gene Regulatory Networks; Hypertension; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Time Factors; Transcriptome | 2018 |
Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'.
Topics: Angiotensin II; Animals; Caloric Restriction; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Hypertension; Male; Mice, Inbred C57BL; Myocardium; Obesity; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Ventricular Remodeling | 2018 |
Testosterone plays a permissive role in angiotensin II-induced hypertension and cardiac hypertrophy in male rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Hypertension; Male; Mesenteric Arteries; Orchiectomy; Rats; Rats, Wistar; Receptors, Androgen; Receptors, Angiotensin; Renin-Angiotensin System; Testosterone | 2019 |
Neuropilin-1 maintains dimethylarginine dimethylaminohydrolase 1 expression in endothelial cells, and contributes to protection from angiotensin II-induced hypertension.
Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Cells, Cultured; Endothelium, Vascular; Hypertension; Male; Mice; Mice, Knockout; Neuropilin-1; Nitric Oxide; Vasoconstrictor Agents | 2019 |
Intracerebroventricular administration of bone marrow-derived cells attenuates angiotensin II-initiated neurogenic hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Bone Marrow Cells; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 2018 |
Hypertension-induced cognitive impairment: insights from prolonged angiotensin II infusion in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cognitive Dysfunction; Disease Models, Animal; Hypertension; Male; Memory, Short-Term; Mice; Motor Activity | 2018 |
Dynamics of Renin, Angiotensin II, and Angiotensin (1-7) during Pregnancy and Predisposition to Hypertension-Associated Complications.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Middle Aged; Peptide Fragments; Pregnancy; Renin; Vasoconstrictor Agents | 2018 |
[Role of ACE2-Ang (1-7)-Mas receptor axis in heart failure with preserved ejection fraction with hypertension].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Atrial Remodeling; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Heart Failure; Humans; Hypertension; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Effects of the selective chymase inhibitor TEI-F00806 on the intrarenal renin-angiotensin system in salt-treated angiotensin I-infused hypertensive mice.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Chymases; Hypertension; Kidney; Male; Mice; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2018 |
Cilostazol ameliorates heart failure with preserved ejection fraction and diastolic dysfunction in obese and non-obese hypertensive mice.
Topics: Angiotensin II; Animals; Biomarkers; Biopsy; Blood Pressure; Cilostazol; Diastole; Disease Models, Animal; Disease Progression; Echocardiography; Energy Metabolism; Fibrosis; Heart Failure; Hypertension; Immunohistochemistry; Male; Mice; Renin; Stroke Volume; Vasodilator Agents; Ventricular Dysfunction, Left | 2018 |
Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat.
Topics: Adaptive Immunity; Angiotensin II; Animals; Aspirin; Biomarkers; Blood Pressure; Blood Vessels; Cardiomegaly; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Disease Susceptibility; Dose-Response Relationship, Drug; Epoprostenol; Hypertension; Kidney; Mice; Rats; Rats, Inbred SHR; Real-Time Polymerase Chain Reaction; RNA, Messenger; Stroke; Systole; T-Lymphocytes; Thromboxanes | 2019 |
Azilsartan attenuates cardiac damage caused by high salt intake through the downregulation of the cardiac (pro)renin receptor and its downstream signals in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Blood Pressure; Down-Regulation; Heart; Hypertension; Myocardium; Oxadiazoles; Phosphorylation; Prorenin Receptor; Rats; Rats, Inbred SHR; Receptors, Cell Surface; Signal Transduction; Sodium Chloride, Dietary; Transforming Growth Factor beta1 | 2018 |
Angiotensin II upregulates CYP4A isoform expression in the rat kidney through angiotensin II type 1 receptor.
Topics: Angiotensin II; Animals; Arachidonic Acid; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cytochrome P-450 CYP4A; Disease Models, Animal; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Protein Isoforms; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles | 2018 |
Mechanism of vasoactive peptide intermedin in vascular collagen remodeling during angiotensin II-induced hypertention.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Collagen; Disease Models, Animal; Hypertension; Mitogen-Activated Protein Kinases; Peptide Hormones; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Vascular Remodeling | 2018 |
Increased expression of miR-33a in monocytes from Mexican hypertensive patients in elevated carotid intima-media thickness.
Topics: Aged; Angiotensin I; Angiotensin II; Carotid Intima-Media Thickness; Case-Control Studies; Female; Humans; Hypertension; Male; MicroRNAs; Middle Aged; Monocytes; Peptide Fragments; Sterol Regulatory Element Binding Proteins | 2018 |
Administration of ubiquitin-activating enzyme UBA1 inhibitor PYR-41 attenuates angiotensin II-induced cardiac remodeling in mice.
Topics: Angiotensin II; Animals; Benzoates; Blood Pressure; Cardiomegaly; Fibrosis; Furans; Gene Expression; Heart; Hypertension; Male; Mice; Myocardium; Pyrazoles; Signal Transduction; Ubiquitin-Activating Enzymes; Ventricular Remodeling | 2018 |
Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol.
Topics: Acetophenones; alpha-Tocopherol; Angiotensin II; Animals; Antioxidants; Blood Pressure; Female; Hemodynamics; Hypertension; Kidney; Lipopolysaccharides; Malondialdehyde; NADPH Oxidases; Oxidative Stress; Pregnancy; Pregnancy Complications, Cardiovascular; Rats, Wistar | 2018 |
Hypertension exaggerates renovascular resistance via miR-122-associated stress response in aging.
Topics: Aging; Angiotensin II; Animals; Basic-Leucine Zipper Transcription Factors; Blood Pressure; Chemokine CCL2; Collagen; Down-Regulation; Heme Oxygenase-1; Histones; Hypertension; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; MicroRNAs; Vascular Resistance | 2018 |
The standardized extract of Nigella sativa and its major ingredient, thymoquinone, ameliorates angiotensin II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzoquinones; Blood Pressure; Hypertension; Male; Nigella sativa; Plant Extracts; Rats; Rats, Wistar | 2018 |
The mechanisms of Ang II-induced hypertensive vascular remodeling under suppression of CD68 in macrophages.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Disease Models, Animal; Hypertension; Macrophages; Male; Mice; Mice, Inbred C57BL; Vascular Remodeling | 2018 |
Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Atenolol; Bestrophins; Blood Pressure; Female; Genetic Association Studies; Humans; Hypertension; Male; Middle Aged; Muscle Proteins; Polymorphism, Single Nucleotide; Sodium Chloride Symporter Inhibitors | 2018 |
The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Phosphoprotein Phosphatases; Transforming Growth Factor beta1; Vascular Remodeling | 2019 |
Vascular angiotensin AT1 receptor neuromodulation in fetal programming of hypertension.
Topics: Angiotensin II; Animal Nutritional Physiological Phenomena; Animals; Arterial Pressure; Disease Models, Animal; Female; Gestational Age; Hypertension; Malnutrition; Maternal Nutritional Physiological Phenomena; Mesenteric Arteries; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System | 2019 |
NFAT5 regulates renal gene expression in response to angiotensin II through Annexin-A2-mediated posttranscriptional regulation in hypertensive rats.
Topics: Angiotensin II; Animals; Annexin A2; Arterial Pressure; Disease Models, Animal; Hypertension; Kidney; Male; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA Processing, Post-Transcriptional; Signal Transduction; Transcription Factors; Up-Regulation | 2019 |
Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis.
Topics: Actins; Adventitia; Angiotensin II; Animals; Aorta; Aortic Diseases; Disease Models, Animal; Febuxostat; Fibroblasts; Fibrosis; Gout Suppressants; Hypertension; Macrophages; Male; Mice, Inbred C57BL; Transforming Growth Factor beta1; Vascular Remodeling; Xanthine Oxidase | 2019 |
Cathepsin B-Mediated NLRP3 Inflammasome Formation and Activation in Angiotensin II -Induced Hypertensive Mice: Role of Macrophage Digestion Dysfunction.
Topics: Angiotensin II; Animals; Cathepsin B; Cell Line; Cell Membrane Permeability; Chalcones; Escherichia coli; Hypertension; Inflammasomes; Losartan; Lysosomes; Macrophages; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; NLR Family, Pyrin Domain-Containing 3 Protein; Phagocytosis; RNA Interference; RNA, Small Interfering | 2018 |
Icariin ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting Nox2-containing NADPH oxidase activation.
Topics: Angiotensin II; Animals; Basilar Artery; Brain; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Flavonoids; Humans; Hyperplasia; Hypertension; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Phytotherapy; Rats, Sprague-Dawley; Reactive Oxygen Species; Stroke; Vascular Remodeling | 2019 |
Interleukin-12p35 knockout promotes macrophage differentiation, aggravates vascular dysfunction, and elevates blood pressure in angiotensin II-infused mice.
Topics: Adult; Aged; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Case-Control Studies; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Female; Humans; Hypertension; Interleukin-12; Interleukin-12 Subunit p35; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Phenotype; Signal Transduction; Vasoconstriction; Vasodilation | 2019 |
Angiotensin II-induced hypertension in rats is only transiently accompanied by lower renal oxygenation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Hypertension; Kidney; Kinetics; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2018 |
Obesity is Associated with Higher Blood Pressure and Higher Levels of Angiotensin II but Lower Angiotensin-(1-7) in Adolescents Born Preterm.
Topics: Adolescent; Angiotensin I; Angiotensin II; Body Mass Index; Cross-Sectional Studies; Female; Humans; Hypertension; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Pediatric Obesity; Peptide Fragments; Pregnancy; Premature Birth; Prospective Studies | 2019 |
Th1-type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II-dependent hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; Antigens, Bacterial; Dose-Response Relationship, Drug; Flow Cytometry; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Porphyromonas gingivalis; Th1 Cells; Ventricular Dysfunction | 2019 |
l-proline supplementation improves nitric oxide bioavailability and counteracts the blood pressure rise induced by angiotensin II in rats.
Topics: Angiotensin II; Animals; Biological Availability; Blood Pressure; Dietary Supplements; Hypertension; Male; Nitric Oxide; Proline; Rats; Rats, Sprague-Dawley | 2019 |
Development and application of low-cost T-ARMS-PCR assay for AGT and CYP11B1 gene polymorphisms.
Topics: Alleles; Angiotensin II; Angiotensinogen; Blood Pressure; Cardiovascular Diseases; Female; Gene Frequency; Genotype; Genotyping Techniques; Humans; Hypertension; Male; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Renin-Angiotensin System; Steroid 11-beta-Hydroxylase | 2019 |
Active-site directed peptide l-Phe-d-His-l-Leu inhibits angiotensin converting enzyme activity and dexamethasone-induced hypertension in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Catalytic Domain; Dexamethasone; Disease Models, Animal; Hypertension; Kinetics; Male; Molecular Docking Simulation; Oligopeptides; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System | 2019 |
Sex-dependent differences in the adverse renal changes induced by an early in life exposure to a high-fat diet.
Topics: Abdominal Fat; Adipokines; Adiposity; Age Factors; Albuminuria; Angiotensin II; Animals; Arterial Pressure; Diet, High-Fat; Disease Progression; Female; Hypertension; Inflammation Mediators; Kidney; Kidney Diseases; Male; Obesity; Rats, Sprague-Dawley; Sex Factors; Time Factors | 2019 |
Effects of hypertension and antihypertensive treatments on sulfatide levels in serum and its metabolism.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Hypertension; Liver; Male; Mice, Inbred C57BL; Oxidative Stress; PPAR gamma; Sulfoglycosphingolipids; Sulfotransferases | 2019 |
Xanthine Oxidase Inhibition as a Potential Treatment for Aortic Stiffness in Hypertension.
Topics: Angiotensin II; Febuxostat; Fibrosis; Humans; Hypertension; Macrophages; Vascular Stiffness; Xanthine Oxidase | 2019 |
Adrenal Tissue-Specific Deletion of TASK Channels Causes Aldosterone-Driven Angiotensin II-Independent Hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Hypertension; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Potassium Channels; Potassium Channels, Tandem Pore Domain; Renin-Angiotensin System; Zona Glomerulosa | 2019 |
Fibroblast growth factor-21 protects against fibrosis in hypertensive heart disease.
Topics: Angiotensin II; Animals; Biopsy; Blood Pressure; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Fibroblast Growth Factors; Fibrosis; Gene Expression Regulation; Heart Rate; Heart Ventricles; Humans; Hypertension; Mice, Knockout; Myocardium; Rats, Sprague-Dawley; RNA, Messenger | 2019 |
Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Diseases; Arrhythmias, Cardiac; Arterial Pressure; Atherosclerosis; Cardiomegaly; Disease Models, Animal; Hypertension; Male; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Propionates; T-Lymphocytes, Regulatory; Th17 Cells | 2019 |
Microglial Cells Impact Gut Microbiota and Gut Pathology in Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Arterial Pressure; Autonomic Nervous System; Disease Models, Animal; Gastrointestinal Microbiome; Hypertension; Infusions, Intraventricular; Intestines; Male; Microglia; Paraventricular Hypothalamic Nucleus; Rats, Inbred SHR; Rats, Inbred WKY; Tetracyclines | 2019 |
Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Apelin; Biopsy; Cardiomegaly; Disease Models, Animal; Echocardiography; Fibrosis; Heart Failure; Hypertension; Mice; Mice, Knockout; Myocardial Contraction; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Ventricular Dysfunction; Ventricular Remodeling | 2019 |
NPR-C (Natriuretic Peptide Receptor-C) Modulates the Progression of Angiotensin II-Mediated Atrial Fibrillation and Atrial Remodeling in Mice.
Topics: Action Potentials; Angiotensin II; Animals; Atrial Fibrillation; Atrial Remodeling; Disease Models, Animal; Disease Progression; Fibrosis; Heart Atria; Heart Rate; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Receptors, Atrial Natriuretic Factor; Time Factors | 2019 |
A novel role for myeloid endothelin-B receptors in hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Endocytosis; Endothelin-1; Humans; Hypertension; Macrophages; Mice; Receptor, Endothelin A; Receptor, Endothelin B | 2019 |
1,2,3,4,6-Penta-O-galloyl-β-d-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Humans; Hydrolyzable Tannins; Hypertension; Inflammation; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Oenothera; Tumor Cells, Cultured; Ventricular Dysfunction | 2019 |
Metformin prevents vascular damage in hypertension through the AMPK/ER stress pathway.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Endoplasmic Reticulum Stress; Endothelium, Vascular; Hypertension; Male; Mesenteric Arteries; Metformin; Mice; Nitric Oxide Synthase Type III; Phosphorylation; Signal Transduction | 2019 |
Protective effect of Fisetin against angiotensin II-induced apoptosis by activation of IGF-IR-PI3K-Akt signaling in H9c2 cells and spontaneous hypertension rats.
Topics: Angiotensin II; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Survival; Flavonoids; Flavonols; Hypertension; Male; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Rats, Inbred SHR; Rats, Wistar; Receptor, IGF Type 1; Receptors, Somatomedin; Signal Transduction | 2019 |
T-Cell Accumulation in the Hypertensive Brain: A Role for Sphingosine-1-Phosphate-Mediated Chemotaxis.
Topics: Angiotensin II; Animals; Brain; Chemokines; Chemotaxis; Cognition Disorders; Female; Hypertension; Lysophospholipids; Male; Memory Disorders; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Phosphotransferases (Alcohol Group Acceptor); Sphingosine; T-Lymphocytes | 2019 |
Wnt/β-catenin regulates blood pressure and kidney injury in rats.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; beta Catenin; Blood Pressure; Blood Urea Nitrogen; Bridged Bicyclo Compounds, Heterocyclic; Collagen Type I; Creatinine; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Fibronectins; Gene Expression Regulation; Hypertension; Kidney; Male; Nephrectomy; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Wnt Proteins; Wnt Signaling Pathway | 2019 |
Dietary Nitrate Reduces Blood Pressure in Rats With Angiotensin II-Induced Hypertension via Mechanisms That Involve Reduction of Sympathetic Hyperactivity.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Dietary Supplements; Disease Models, Animal; Hypertension; Male; Nitrates; Nitric Oxide; Rats; Rats, Wistar; Sympathetic Nervous System | 2019 |
Effect of Ocimum basilicum, Ocimum selloi, and Rosmarinic Acid on Cerebral Vascular Damage in a Chronic Hypertension Model.
Topics: Angiotensin II; Animals; Blood Pressure; Cinnamates; Corticosterone; Cytokines; Depsides; Dose-Response Relationship, Drug; Hypertension; Hypothalamo-Hypophyseal System; Male; Maze Learning; Mice, Inbred ICR; Ocimum; Ocimum basilicum; Pituitary-Adrenal System; Plant Extracts; Random Allocation; Rosmarinic Acid; Spatial Navigation | 2019 |
Calcineurin dephosphorylates Kelch-like 3, reversing phosphorylation by angiotensin II and regulating renal electrolyte handling.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Calcineurin; Calcineurin Inhibitors; Carrier Proteins; Cullin Proteins; Gene Expression Regulation; Germ-Line Mutation; Humans; Hyperkalemia; Hypertension; Kidney; Kidney Tubules, Distal; Mice; Microfilament Proteins; Multiprotein Complexes; Phosphorylation; Protein Serine-Threonine Kinases; Renal Insufficiency; T-Lymphocytes; Tacrolimus; Ubiquitination | 2019 |
Histone deacetylase inhibitor LMK235 attenuates vascular constriction and aortic remodelling in hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Diseases; Benzamides; Gene Expression Regulation; Histone Deacetylase Inhibitors; Hypertension; Male; Mice; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Vasoconstriction | 2019 |
Novel Role of T Cells and IL-6 (Interleukin-6) in Angiotensin II-Induced Microvascular Dysfunction.
Topics: Adaptive Immunity; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Flow Cytometry; Hypertension; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Signal Transduction; T-Lymphocytes; Thrombosis | 2019 |
Complex Role for E-Prostanoid 4 Receptors in Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Dinoprostone; Disease Models, Animal; Hypertension; Infusions, Intravenous; Mice; Mice, Transgenic; Receptors, Prostaglandin E, EP4 Subtype; Rest; Signal Transduction; Vasoconstrictor Agents; Vasodilation | 2019 |
Angiotensin II-induced hypertension and cardiac hypertrophy are differentially mediated by TLR3- and TLR4-dependent pathways.
Topics: Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Hypertension; Immunity, Innate; Inflammation Mediators; Kidney; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptor, Angiotensin, Type 1; Signal Transduction; Toll-Like Receptor 3; Toll-Like Receptor 4 | 2019 |
BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cell Proliferation; Gene Knockdown Techniques; Humans; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Proto-Oncogene Proteins c-bcl-6; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Remodeling | 2019 |
Microglia, the Missing Link in the Brain-Gut-Hypertension Axis.
Topics: Angiotensin II; Brain; Gastrointestinal Microbiome; Humans; Hypertension; Microglia | 2019 |
Comparing the effects of diethylhexyl phthalate and dibutyl phthalate exposure on hypertension in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Dibutyl Phthalate; Diethylhexyl Phthalate; Estradiol; Hypertension; Male; Mice; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A | 2019 |
Class I histone deacetylase inhibitor MS-275 attenuates vasoconstriction and inflammation in angiotensin II-induced hypertension.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta; Benzamides; Blood Pressure; Cell Adhesion Molecules; Histone Deacetylase Inhibitors; Hypertension; Inflammation; Macrophages; Male; Mice; Myocytes, Smooth Muscle; NADPH Oxidase 1; Nitric Oxide; Pyridines; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Up-Regulation; Vasoconstriction | 2019 |
2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury.
Topics: 2-Methoxyestradiol; Angiotensin II; Animals; Blood Pressure; Fibrosis; Glomerular Filtration Rate; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Kidney; Kidney Diseases; Male; Rats, Sprague-Dawley; Renin-Angiotensin System; Vascular Remodeling; Ventricular Function, Left; Ventricular Remodeling | 2019 |
Time course of decompensation after angiotensin II and high-salt diet in Balb/CJ mice suggests pulmonary hypertension-induced cardiorenal syndrome.
Topics: Angiotensin II; Animals; Blood Pressure; Cardio-Renal Syndrome; Diet; Heart Failure; Hypertension; Hypertension, Pulmonary; Male; Mice, Inbred BALB C; Myocardium; Sodium Chloride, Dietary; Time Factors; Water-Electrolyte Imbalance | 2019 |
Angiotensin type 1a receptors in the median preoptic nucleus support intermittent hypoxia-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Hypoxia; Injections, Intraventricular; Male; Oxidative Stress; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2019 |
RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity.
Topics: Angiotensin II; Animals; Cullin Proteins; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; HEK293 Cells; Humans; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Nitric Oxide; rho GTP-Binding Proteins; rho-Associated Kinases; Vascular Stiffness; Vasodilation | 2019 |
Effects of methyl-beta-cyclodextrin on blood-brain barrier permeability in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Astrocytes; beta-Cyclodextrins; Blood Pressure; Blood-Brain Barrier; Caveolin 1; Cerebral Cortex; Claudin-5; Endothelial Cells; Hippocampus; Hypertension; Male; Permeability; Rats; Rats, Sprague-Dawley | 2019 |
Membrane raft redox signalling contributes to endothelial dysfunction and vascular remodelling of thoracic aorta in angiotensin II-infused rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Hypertension; Male; Membrane Microdomains; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling | 2019 |
MiR-204 regulates type 1 IP
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Humans; Hypertension; Inositol 1,4,5-Trisphosphate Receptors; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Muscle Contraction; Muscle, Smooth, Vascular; Vasoconstriction | 2019 |
MicroRNA-31 Regulates Immunosuppression in Ang II (Angiotensin II)-induced Hypertension by Targeting Ppp6C (Protein Phosphatase 6c).
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Hypertension; Immunity, Cellular; Immunosuppression Therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Phosphoprotein Phosphatases; RNA; T-Lymphocytes, Regulatory | 2019 |
miR-431-5p Knockdown Protects Against Angiotensin II-Induced Hypertension and Vascular Injury.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Hypertension; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; RNA; T-Lymphocytes, Regulatory; Vascular System Injuries | 2019 |
Connexin37-Dependent Mechanisms Selectively Contribute to Modulate Angiotensin II -Mediated Hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Connexins; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gap Junction alpha-4 Protein; Hypertension; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; NG-Nitroarginine Methyl Ester; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 2; Renin; Vasoconstrictor Agents | 2019 |
Long non-coding RNA and mRNA analysis of Ang II-induced neuronal dysfunction.
Topics: Angiotensin II; Apoptosis; Cell Line; Computational Biology; Gene Expression Profiling; Hedgehog Proteins; Humans; Hypertension; Lipid Metabolism; Mitochondria; Neurons; Oligonucleotide Array Sequence Analysis; RNA, Long Noncoding; RNA, Messenger; Transcriptome | 2019 |
Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4-ROS-ADAM17 pathway.
Topics: ADAM17 Protein; Angiotensin II; Animals; Aorta, Abdominal; Cardiomegaly; Constriction, Pathologic; Gene Expression Regulation; Humans; Hypertension; Indole Alkaloids; MAP Kinase Signaling System; Myocytes, Cardiac; NADPH Oxidase 4; Quinazolines; Rats; Rats, Inbred Dahl; Reactive Oxygen Species | 2019 |
Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction.
Topics: Anemia, Megaloblastic; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Genetic Loci; Hypertension; Macrophages; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Mitochondria; Phenotype; Tetrahydrofolate Dehydrogenase; Ultrasonography | 2019 |
Rivaroxaban, a Direct Factor Xa Inhibitor, Ameliorates Hypertensive Renal Damage Through Inhibition of the Inflammatory Response Mediated by Protease-Activated Receptor Pathway.
Topics: Albuminuria; Angiotensin II; Animals; Blood Coagulation; Factor Xa Inhibitors; Gene Knockdown Techniques; Glomerular Basement Membrane; Glomerular Mesangium; Humans; Hypertension; In Vitro Techniques; Inflammation; Kidney Glomerulus; Male; Mice; Mice, Transgenic; Podocytes; Receptor, PAR-2; Renal Insufficiency, Chronic; Renin; Reverse Transcriptase Polymerase Chain Reaction; Rivaroxaban; Vasoconstrictor Agents | 2019 |
Blood pressure lowering effect of Ficus deltoidea var kunstleri in spontaneously hypertensive rats: possible involvement of renin-angiotensin-aldosterone system, endothelial function and anti-oxidant system.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Captopril; Disease Models, Animal; Drugs, Chinese Herbal; Ficus; Hypertension; Losartan; Male; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Plant Extracts; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 2019 |
Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Hypertension; Kidney Tubules, Proximal; Laser Capture Microdissection; Mice; Mice, Knockout; Nephrons; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents | 2019 |
Activation of ADAM17 (A Disintegrin and Metalloprotease 17) on Glutamatergic Neurons Selectively Promotes Sympathoexcitation.
Topics: ADAM17 Protein; Angiotensin II; Animals; Autonomic Nervous System; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Paraventricular Hypothalamic Nucleus; Sodium Chloride, Dietary | 2019 |
Prenatal cold exposure causes hypertension in offspring by hyperactivity of the sympathetic nervous system.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cold Temperature; Denervation; Dipeptides; Heart Rate; Heterocyclic Compounds, 3-Ring; Hypertension; Kidney; Male; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sympathetic Nervous System | 2019 |
The TIR/BB-loop mimetic AS-1 prevents Ang II-induced hypertensive cardiac hypertrophy via NF-κB dependent downregulation of miRNA-143.
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Down-Regulation; Gene Expression Regulation; Hypertension; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; MicroRNAs; Myocytes, Cardiac; NF-kappa B; Phosphorylation; Pyrrolidines; Rats; Valine | 2019 |
The absence of sympathoexcitation during the development of hypertension in Cyp1a1 Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP1A1; Hypertension; Male; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Vasoconstriction | 2019 |
Are Reactive Oxygen Species Important Mediators of Vascular Dysfunction?
Topics: Angiotensin II; Humans; Hypertension; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species | 2020 |
Angiotensin III/AT
Topics: Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Hypertension; Kidney; Kidney Tubules, Proximal; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2019 |
Alamandine attenuates long‑term hypertension‑induced cardiac fibrosis independent of blood pressure.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Collagen Type I; Collagen Type I, alpha 1 Chain; Fibrosis; Heart Ventricles; Hypertension; Imidazoles; Male; Matrix Metalloproteinase 9; Oligopeptides; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 2019 |
Stress-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Blockade of Angiotensin-Converting Enzyme or Tumor Necrosis Factor-α.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain; Captopril; Cytokines; Disease Models, Animal; Hypertension; Inflammation Mediators; Male; Microglia; Pentoxifylline; Rats, Long-Evans; Rats, Sprague-Dawley; Renin-Angiotensin System; Stress Disorders, Post-Traumatic; Tumor Necrosis Factor Inhibitors | 2019 |
Angiotensin II-induced hypertension increases the mutant frequency in rat kidney.
Topics: Angiotensin II; Animals; Blood Pressure; DNA Damage; Hypertension; Kidney; Lac Repressors; Male; Mutation; Oxidative Stress; Rats; Rats, Transgenic; Renin-Angiotensin System | 2019 |
Histone deacetylase 6 inhibitor tubastatin A attenuates angiotensin II-induced hypertension by preventing cystathionine γ-lyase protein degradation.
Topics: Angiotensin II; Animals; Aorta; Cystathionine gamma-Lyase; Endothelial Cells; HEK293 Cells; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Hydrogen Sulfide; Hydroxamic Acids; Hypertension; Indoles; Male; Mice, Inbred C57BL; Proteolysis | 2019 |
Elevated bone marrow sympathetic drive precedes systemic inflammation in angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Bone Marrow; CD4-Positive T-Lymphocytes; Disease Models, Animal; Femur; Hypertension; Inflammation; Male; Microglia; Neuroimmunomodulation; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors | 2019 |
Gut Microbiota Plays a Central Role to Modulate the Plasma and Fecal Metabolomes in Response to Angiotensin II.
Topics: Angiotensin II; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Feces; Female; Gastrointestinal Microbiome; Hypertension; Metabolome; Mice; Mice, Inbred C57BL; Plasma; Random Allocation; Role | 2019 |
High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension.
Topics: Adolescent; Adoptive Transfer; Adult; Angiotensin II; Animals; Aorta; Bacteria; Blood Pressure; CD11c Antigen; Colon; Cytokines; Dendritic Cells; Disease Models, Animal; Dysbiosis; Female; Gastrointestinal Microbiome; Humans; Hypertension; Inflammation; Lipids; Lymph Nodes; Male; Mice; Mice, Inbred C57BL; Middle Aged; Myeloid Cells; Peyer's Patches; RNA, Ribosomal, 16S; Sodium Chloride; Sodium Chloride, Dietary; Young Adult | 2019 |
Redox-sensitive calcium/calmodulin-dependent protein kinase IIα in angiotensin II intra-neuronal signaling and hypertension.
Topics: Amino Acids; Angiotensin II; Animals; Blood Pressure; Brain; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line; Hypertension; Male; Mice; Mice, Inbred C57BL; Mutation; Neurons; Oxidation-Reduction; Potassium Channels; Reactive Oxygen Species; Signal Transduction; Subfornical Organ; Superoxide Dismutase | 2019 |
The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice.
Topics: Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Cytokines; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Endothelial Cells; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Inflammation; Male; Malondialdehyde; Mice; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phytotherapy; Superoxide Dismutase; Vascular Remodeling | 2019 |
Alteration of the IL-33-sST2 pathway in hypertensive patients and a mouse model.
Topics: Angiotensin II; Animals; Aorta; Case-Control Studies; Disease Models, Animal; Female; Humans; Hypertension; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Middle Aged; Receptors, Interleukin-1 | 2019 |
Cardiovascular and hidroelectrolytic changes in rats fed with high-fat diet.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, High-Fat; Drinking; Eating; Hypertension; Injections, Intraventricular; Male; Obesity; Rats; Rats, Sprague-Dawley; Water-Electrolyte Balance | 2019 |
Rosmarinic acid improves hypertension and skeletal muscle glucose transport in angiotensin II-treated rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cinnamates; Depsides; Glucose; Hypertension; Insulin; Male; Muscle, Skeletal; Organ Size; Rats; Rats, Sprague-Dawley; Rosmarinic Acid; Signal Transduction | 2019 |
Angiopoietin-Like 7 Contributes to Angiotensin II-Induced Proliferation, Inflammation and Apoptosis in Vascular Smooth Muscle Cells.
Topics: Angiopoietin-Like Protein 7; Angiopoietin-like Proteins; Angiotensin II; Apoptosis; Cell Cycle; Cell Line; Cell Proliferation; Down-Regulation; Humans; Hypertension; Inflammation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Small Interfering | 2019 |
Sex-related differences in the intratubular renin-angiotensin system in two-kidney, one-clip hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Constriction; Disease Models, Animal; Estrogens; Female; Hypertension; Hypertrophy, Left Ventricular; Kidney Tubules; Macrophages; Male; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renal Artery; Renin-Angiotensin System; Sex Factors; Signal Transduction | 2019 |
In Vitro Vascular-Protective Effects of a Tilapia By-Product Oligopeptide on Angiotensin II-Induced Hypertensive Endothelial Injury in HUVEC by Nrf2/NF-κB Pathways.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Molecular Docking Simulation; NF-E2-Related Factor 2; NF-kappa B; Oligopeptides; Oxidative Stress; Protein Binding; Signal Transduction; Tilapia; Vascular Diseases | 2019 |
Targeting HSP90 attenuates angiotensin II-induced adventitial remodelling via suppression of mitochondrial fission.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Thoracic; Benzoquinones; Calcineurin; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dynamins; Fibroblasts; HSP90 Heat-Shock Proteins; Hypertension; Lactams, Macrocyclic; Male; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Molecular Targeted Therapy; Phenotype; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling | 2020 |
Age-related changes in the local intestinal renin-angiotensin system in normotensive and spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Hypertension; Intestines; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2019 |
G-Protein-Coupled Estrogen Receptor Agonist G1 Improves Diastolic Function and Attenuates Cardiac Renin-Angiotensin System Activation in Estrogen-Deficient Hypertensive Rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cyclopentanes; Diastole; Disease Models, Animal; Estrogens; Female; Hypertension; Myocardium; Ovariectomy; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Quinolines; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Ventricular Dysfunction, Left; Ventricular Function, Left | 2019 |
Re: Zhou Y, Zhang R, Wang G, et al. Coexistence effect of hypertension and angiotensin II on the risk of coronary heart disease: a population-based prospective cohort study among Inner Mongolians in China. Curr Med Res Opin. 2019;35:1473-1478.
Topics: Angiotensin II; China; Cohort Studies; Coronary Disease; Humans; Hypertension; Prospective Studies | 2020 |
Role of sodium/glucose cotransporter inhibition on a rat model of angiotensin II-dependent kidney damage.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzhydryl Compounds; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Glucose; Glucosides; Hypertension; Losartan; Male; Microvilli; Proteinuria; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Regulation of YAP by Mammalian Target of Rapamycin Complex 1 in Endothelial Cells Controls Blood Pressure Through COX-2/mPGES-1/PGE
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Blood Pressure; Cell Cycle Proteins; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Endothelial Cells; Endothelium, Vascular; Hypertension; Indomethacin; Mechanistic Target of Rapamycin Complex 1; Mesenteric Arteries; Mice; Phosphoproteins; Prostaglandin-E Synthases; Signal Transduction; Vasodilation; YAP-Signaling Proteins | 2019 |
Protective Effects of Combination of Radix Astragali and Radix Salviae Miltiorrhizae on Kidney of Spontaneously Hypertensive Rats and Renal Intrinsic Cells.
Topics: Angiotensin II; Animals; Astragalus propinquus; Biomarkers; Blotting, Western; Cells, Cultured; Drugs, Chinese Herbal; Hypertension; Kidney; Male; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Salvia miltiorrhiza | 2020 |
Construction, expression and immunogenicity of a novel anti-hypertension angiotensin II vaccine based on hepatitis A virus-like particle.
Topics: Angiotensin II; Animals; Antibodies; Drug Carriers; Hepatitis A Vaccines; Hypertension; Male; Rats; Sf9 Cells; Spodoptera; Treatment Outcome; Vaccination; Vaccines, Synthetic; Vaccines, Virus-Like Particle | 2013 |
Early interference with p44/42 mitogen-activated protein kinase signaling in hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Hypertension; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2013 |
Spreading vasodilatation in the murine microcirculation: attenuation by oxidative stress-induced change in electromechanical coupling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Calcium Channels, L-Type; Calcium Channels, T-Type; Connexins; Endothelium, Vascular; Gap Junction alpha-5 Protein; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Models, Cardiovascular; Oxidative Stress; Renin; Tetrazoles; Vasodilation | 2013 |
Low-dose angiotensin II infusion restores vascular function in cerebral arteries of high salt-fed rats by increasing copper/zinc superoxide dimutase expression.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Cerebral Arteries; Copper; Disease Models, Animal; Hypertension; Infusions, Intravenous; Male; Rats; Rats, Inbred BN; Recovery of Function; Superoxide Dismutase; Vasoconstrictor Agents; Vasodilation | 2013 |
Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred Lew; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Tetrazoles | 2013 |
Membrane trafficking of NADPH oxidase p47(phox) in paraventricular hypothalamic neurons parallels local free radical production in angiotensin II slow-pressor hypertension.
Topics: Angiotensin II; Animals; Cell Membrane; Dendrites; Drug Administration Schedule; Drug Delivery Systems; Excitatory Amino Acid Agonists; Green Fluorescent Proteins; HEK293 Cells; Humans; Hypertension; In Vitro Techniques; Intracellular Membranes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; N-Methylaspartate; NADPH Oxidases; Neuroglia; Neurons; Paraventricular Hypothalamic Nucleus; Protein Transport; Reactive Oxygen Species; Transfection; Vasoconstrictor Agents; Vasopressins | 2013 |
Impaired acetylcholine-induced endothelium-dependent aortic relaxation by caveolin-1 in angiotensin II-infused apolipoprotein-E (ApoE-/-) knockout mice.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Apolipoproteins E; beta-Cyclodextrins; Blood Pressure; Caveolae; Caveolin 1; Endothelium, Vascular; Gene Expression Regulation; Heart Rate; Hypertension; Injections, Subcutaneous; Male; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Vasodilation | 2013 |
Antihypertensive actions of moderate hyperbilirubinemia: role of superoxide inhibition.
Topics: Acetophenones; Angiotensin II; Animals; Bilirubin; Blood Pressure; Disease Models, Animal; Drug Implants; Enzyme Inhibitors; Hyperbilirubinemia; Hypertension; Male; Mice; Mice, Inbred C57BL; Superoxides; Vasoconstrictor Agents | 2013 |
Angiotensin-(1-7) inhibits autophagy in the brain of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Autophagy; Blood Pressure; Brain; Hypertension; Imidazoles; Male; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2013 |
Central mineralocorticoid receptors and the role of angiotensin II and glutamate in the paraventricular nucleus of rats with angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Eplerenone; Glutamic Acid; Heart Rate; Hypertension; Infusions, Intravenous; Infusions, Intraventricular; Kynurenic Acid; Male; Mineralocorticoid Receptor Antagonists; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Glutamate; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone; Tetrazoles | 2013 |
TIMP3 is the primary TIMP to regulate agonist-induced vascular remodelling and hypertension.
Topics: Angiotensin II; Animals; Arterial Pressure; Carotid Arteries; Collagen; Disease Models, Animal; Elastin; Gelatinases; Hypertension; Matrix Metalloproteinase Inhibitors; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Vasoconstriction; Vasodilation | 2013 |
Additional antihypertensive effect of magnesium supplementation with an angiotensin II receptor blocker in hypomagnesemic rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Dietary Supplements; Disease Models, Animal; Hypertension; Kidney; Magnesium; Magnesium Deficiency; Male; Rats; Rats, Sprague-Dawley; Systole; Time Factors | 2013 |
Enhanced angiotensin receptor-associated protein in renal tubule suppresses angiotensin-dependent hypertension.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; DNA; Gene Expression Regulation; Hypertension; Kidney Tubules, Distal; Male; Mice; Mice, Transgenic; Polymerase Chain Reaction; Renin-Angiotensin System | 2013 |
Angiotensin II type 1 receptor-associated protein: a novel modulator of angiotensin II actions in the nephron.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; DNA; Gene Expression Regulation; Hypertension; Kidney Tubules, Distal; Male | 2013 |
Urinary angiotensinogen as a marker of intrarenal angiotensin II activity in adolescents with primary hypertension.
Topics: Adolescent; Angiotensin II; Angiotensinogen; Biomarkers; Body Mass Index; Chi-Square Distribution; Child; Creatinine; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypertension; Hyperuricemia; Kidney; Linear Models; Lipids; Male; Multivariate Analysis; Predictive Value of Tests; Prospective Studies; Up-Regulation; Uric Acid | 2013 |
Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice.
Topics: Amlodipine; Angiotensin II; Animals; Aorta, Thoracic; Biomarkers; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemodynamics; Hypertension; Macrophages; Mice; omega-Conotoxin GVIA; Oxidative Stress; Reactive Oxygen Species; Vasodilation; Vasodilator Agents | 2013 |
Decrease in blood pressure and regression of cardiovascular complications by angiotensin II vaccine in mice.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Antibody Formation; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Immunization; Kidney; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Models, Cardiovascular; Myocardium; Rats; Rats, Inbred SHR; T-Lymphocytes; Vaccines; Ventricular Remodeling | 2013 |
Chemerin connects fat to arterial contraction.
Topics: Adipokines; Adipose Tissue; Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Chemokines; Disease Models, Animal; Gene Expression Regulation; Humans; Hypertension; Immunochemistry; Intercellular Signaling Peptides and Proteins; Mesenteric Arteries; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Rats; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Vasoconstriction | 2013 |
Angiotensin II stimulates basolateral 10-pS Cl channels in the thick ascending limb.
Topics: Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Chloride Channels; Disease Models, Animal; Female; Hypertension; Loop of Henle; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2013 |
Angiotensin II slow-pressor hypertension enhances NMDA currents and NOX2-dependent superoxide production in hypothalamic paraventricular neurons.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Models, Animal; N-Methylaspartate; NADPH Oxidase 2; NADPH Oxidases; Neurons; Nitric Oxide; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Reactive Oxygen Species; Signal Transduction; Superoxides | 2013 |
Exercise, load and remodelling: do we know what we think we know?
Topics: Angiotensin II; Animals; Female; Hypertension; Physical Conditioning, Animal; Ventricular Remodeling | 2013 |
Is exercise really deleterious for the hypertensive heart?
Topics: Angiotensin II; Animals; Female; Hypertension; Physical Conditioning, Animal; Ventricular Remodeling | 2013 |
Reply from Klaus-Dieter Schluter and Rolf Schreckenberg.
Topics: Angiotensin II; Animals; Female; Hypertension; Physical Conditioning, Animal; Ventricular Remodeling | 2013 |
Real-time electrochemical detection of ATP and H₂O₂ release in freshly isolated kidneys.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Biosensing Techniques; Blood Pressure; Diet, Sodium-Restricted; Disease Models, Animal; Electrochemical Techniques; Equipment Design; Hydrogen Peroxide; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Microelectrodes; Perfusion; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary; Time Factors | 2013 |
The absence of intrarenal ACE protects against hypertension.
Topics: Angiotensin II; Animals; Hypertension; Kidney; Liver; Loop of Henle; Male; Mice; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Protein Serine-Threonine Kinases; Receptors, Drug; Renin-Angiotensin System; Sodium; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Solute Carrier Family 12, Member 3; Symporters; Water | 2013 |
Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Circadian Rhythm; Disease Models, Animal; Hypertension; Male; Metabolic Syndrome; Rats, Inbred SHR; Rats, Inbred WKY | 2013 |
Relative atrial natriuretic peptide deficiency and inadequate renin and angiotensin II suppression in obese hypertensive men.
Topics: Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Composition; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Obesity; Prognosis; Renin; Renin-Angiotensin System | 2013 |
Beneficial effects of nebivolol and hydrochlorothiazide combination in spontaneously hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Antihypertensive Agents; Benzopyrans; Blood Pressure; Drinking; Drug Synergism; Drug Therapy, Combination; Ethanolamines; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Nebivolol; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Wistar; Vasodilation | 2013 |
Inhibition of TNF in the brain reverses alterations in RAS components and attenuates angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Cytokines; Etanercept; Hypertension; Immunoglobulin G; Male; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Tumor Necrosis Factor; Renin-Angiotensin System; Tumor Necrosis Factor-alpha | 2013 |
Angiotensin-converting enzyme inhibitor does not suppress renal angiotensin II levels in angiotensin I-infused rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Imidazoles; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Thiazepines | 2013 |
Angiotensin II regulates microRNA-132/-212 in hypertensive rats and humans.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Endothelin-1; Female; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Mice; Mice, Inbred C57BL; MicroRNAs; Oligonucleotide Array Sequence Analysis; Organ Specificity; Rats, Sprague-Dawley; Reproducibility of Results; Vasoconstrictor Agents | 2013 |
Endothelin ET(B) receptors contribute to sex differences in blood pressure elevation in angiotensin II hypertensive rats on a high-salt diet.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Drug Synergism; Endothelin B Receptor Antagonists; Female; Hypertension; Male; Proteinuria; Pyrrolidines; Rats; Receptor, Endothelin B; Sex Characteristics; Sodium Chloride, Dietary | 2013 |
Role of complement 3a in the growth of mesangial cells from stroke-prone spontaneously hypertensive rats.
Topics: Actins; Angiotensin II; Animals; Arginine; Benzhydryl Compounds; Cell Proliferation; Complement C3a; Gene Expression; Hypertension; Kidney Cortex; Male; Mesangial Cells; Myocytes, Smooth Muscle; Osteopontin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Complement; RNA, Messenger; Stroke | 2014 |
Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition.
Topics: Angiotensin II; Animals; Blood Pressure; Epithelial Sodium Channels; Hypertension; Immunoblotting; Immunohistochemistry; Kidney; Male; Membrane Transport Proteins; Nephrons; Rats; Rats, Sprague-Dawley; Sodium | 2013 |
Unsupported assumption in model of salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Hypertension; Models, Biological; Sodium | 2013 |
Reply from V. A. Averina, H. G. Othmer, G. D. Fink and J. W. Osborn.
Topics: Angiotensin II; Animals; Hypertension; Models, Biological; Sodium | 2013 |
[Effect of Rhodiola Sacra on left ventricular remodeling and its mechanism in spontaneously hypertensive rats].
Topics: Aldosterone; Angiotensin II; Animals; Drugs, Chinese Herbal; Hypertension; Male; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Rhodiola; Ventricular Remodeling | 2013 |
Smad7 inhibits angiotensin II-induced hypertensive cardiac remodelling.
Topics: Angiotensin II; Animals; Fibrosis; Hypertension; Male; Mice; MicroRNAs; Myocardium; NF-kappa B; Smad7 Protein; Sp1 Transcription Factor; Transforming Growth Factor beta; Ventricular Remodeling | 2013 |
Protective effects of Sapindus saponins in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Collagen; Female; Hypertension; Interleukin-1; Interleukin-6; Male; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protective Agents; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sapindus; Saponins; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2015 |
Blood pressure-renal blood flow relationships in conscious angiotensin II- and phenylephrine-infused rats.
Topics: Angiotensin II; Animals; Blood Pressure; Consciousness; Disease Models, Animal; Heart Rate; Hemodynamics; Hypertension; Infusions, Intravenous; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Renal Circulation; Telemetry; Vasoconstrictor Agents | 2013 |
N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats.
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Body Weight; Cardiomegaly; CD4-Positive T-Lymphocytes; Collagen; Extracellular Matrix; Hypertension; Inflammation; Lung; Male; NF-kappa B; Oligopeptides; Organ Size; Protein-Lysine 6-Oxidase; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Effect of CCL5 on dimethylarginine dimethylaminohydrolase-1 production in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Cell Proliferation; Chemokine CCL5; Endothelin-1; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; RNA Interference; RNA, Small Interfering | 2013 |
Fibulin-2 deficiency attenuates angiotensin II-induced cardiac hypertrophy by reducing transforming growth factor-β signalling.
Topics: Angiotensin II; Animals; Calcium-Binding Proteins; Cardiomegaly; Extracellular Matrix Proteins; Fibrosis; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Signal Transduction; Transforming Growth Factor beta; Vasoconstrictor Agents | 2014 |
[Effects of sapindus saponins on inflammatory response mediated by Ang II/p38MAPK pathway and cardiac hypertrophy in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Sapindus; Saponins | 2013 |
Effects of traditional Chinese medicine Xin-Ji-Er-Kang formula on 2K1C hypertensive rats: role of oxidative stress and endothelial dysfunction.
Topics: Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Australia; Blood Pressure; Drugs, Chinese Herbal; Endothelium, Vascular; Heart; Hypertension; Magnoliopsida; Male; Malondialdehyde; Medicine, Chinese Traditional; Myocardium; Nitric Oxide; Oxidative Stress; Phytotherapy; Rats; Superoxide Dismutase; Vasodilation; Ventricular Remodeling | 2013 |
Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B2; Dose-Response Relationship, Drug; Eplerenone; Fadrozole; Heart Rate; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone | 2013 |
Enhanced development of azoxymethane-induced colonic preneoplastic lesions in hypertensive rats.
Topics: Adipose Tissue; Angiotensin II; Animals; Azoxymethane; Carcinogens; Catalase; Chemokine CCL2; Colorectal Neoplasms; Cyclooxygenase 2; Glutathione Peroxidase; Hypertension; Insulin Resistance; Interleukin-6; Intestinal Mucosa; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Precancerous Conditions; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Zucker; RNA, Messenger; Tumor Necrosis Factor-alpha | 2013 |
Inhibition of platelet activation by clopidogrel prevents hypertension-induced cardiac inflammation and fibrosis.
Topics: Angiotensin II; Animals; Clopidogrel; Fibrosis; Hypertension; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Myocarditis; Myocardium; Platelet Activation; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Ticlopidine; Transforming Growth Factor beta | 2013 |
Metformin treatment improves erectile function in an angiotensin II model of erectile dysfunction.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Antihypertensive Agents; Arterial Pressure; Disease Models, Animal; Erectile Dysfunction; Humans; Hypertension; Male; Metformin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penile Erection; Penis; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Down-Regulation; Fibrosis; Heart; Hypertension; Inflammation; Male; Mice; Mice, Knockout; MicroRNAs; Myocardium; NF-kappa B; Signal Transduction; Smad7 Protein | 2013 |
Acute vascular effects of atorvastatin in hypertensive men: a pilot study.
Topics: Angiotensin II; Atorvastatin; Endothelium, Vascular; Forearm; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Middle Aged; Pilot Projects; Pyrroles; Regional Blood Flow; Vasoconstriction; Vasodilation | 2013 |
Protective role of the endothelial isoform of nitric oxide synthase in ANG II-induced inflammatory responses in the kidney.
Topics: Angiogenesis Inducing Agents; Angiotensin II; Animals; Hypertension; Inflammation; Male; Mice; Mice, Knockout; Nephritis; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Ribonuclease, Pancreatic; Up-Regulation | 2013 |
Complement 3 activates the renal renin-angiotensin system by induction of epithelial-to-mesenchymal transition of the nephrotubulus in mice.
Topics: Aldosterone; Amides; Angiotensin II; Animals; Antihypertensive Agents; Complement C3; Epithelial-Mesenchymal Transition; Fumarates; Hypertension; Kidney; Kruppel-Like Transcription Factors; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Nephrosclerosis; Orphan Nuclear Receptors; Renin; Renin-Angiotensin System; Transforming Growth Factor beta1; Ureteral Obstruction | 2013 |
A flow cytometric method for the analysis of macrophages in the vascular wall.
Topics: Angiotensin II; Animals; Antigens, Differentiation; Aorta; Apolipoproteins E; Cells, Cultured; Flow Cytometry; Fluorescent Dyes; Hypercholesterolemia; Hypertension; Leukocyte Common Antigens; Macrophages; Male; Mice; Mice, Inbred C57BL | 2013 |
Circulating aminopeptidase activities in men and women with essential hypertension.
Topics: Adult; Aged; Aminopeptidases; Angiotensin II; Blood Pressure; CD13 Antigens; Essential Hypertension; Estradiol; Female; Glutamyl Aminopeptidase; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Sex Factors; Testosterone; Thyrotropin; Thyroxine | 2013 |
Senescence marker protein 30 inhibits angiotensin II-induced cardiac hypertrophy and diastolic dysfunction.
Topics: Angiotensin II; Animals; Antioxidants; Ascorbic Acid; Blood Pressure; Calcium-Binding Proteins; Cardiomegaly; Cellular Senescence; Diastole; Echocardiography; Fibrosis; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; Oxidative Stress; Promoter Regions, Genetic; Superoxides | 2013 |
Amelioration of angiotensin II-induced salt-sensitive hypertension by liver-type fatty acid-binding protein in proximal tubules.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Fatty Acid-Binding Proteins; Hypertension; Inflammation; Kidney; Kidney Tubules, Proximal; Mice; Mice, Transgenic; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2013 |
Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
Topics: Actins; Adaptation, Physiological; Aging; Angiotensin II; Animals; Behavior, Animal; Blood-Brain Barrier; Cerebrovascular Circulation; Cytokines; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microvessels; Middle Cerebral Artery; TRPC Cation Channels; TRPC6 Cation Channel; Up-Regulation | 2013 |
Collagenase-resistant collagen promotes mouse aging and vascular cell senescence.
Topics: Aging; Angiotensin II; Animals; Aorta; Cellular Senescence; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagenases; Embryo, Mammalian; Fibroblasts; Humans; Hypertension; Integrin alphaVbeta3; Longevity; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Phenotype; Proteolysis; Stress, Physiological | 2014 |
Effects of nicotine on cardiovascular remodeling in a mouse model of systemic hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Disease Models, Animal; Hypertension; Infusion Pumps; Male; Mice; Mice, Inbred C57BL; Nicotine; Treatment Outcome; Ventricular Remodeling | 2013 |
The effects of angiotensin II and angiotensin-(1-7) in the rostral ventrolateral medulla of rats on stress-induced hypertension.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Gene Expression Regulation; Heart Rate; Hypertension; Male; Medulla Oblongata; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Stress, Psychological | 2013 |
Sonic hedgehog carried by microparticles corrects angiotensin II-induced hypertension and endothelial dysfunction in mice.
Topics: Acetylcholine; Angiotensin II; Animals; Anions; Aorta; Blood Pressure; Cell Line; Cell-Derived Microparticles; Coronary Circulation; Endothelium, Vascular; Heart Rate; Hedgehog Proteins; Humans; Hypertension; In Vitro Techniques; Infusion Pumps; Male; Mesenteric Arteries; Mice; Nitric Oxide; Oxidative Stress; Superoxides; Systole; Vasodilation | 2013 |
Non-alcoholic steatohepatitis and preneoplastic lesions develop in the liver of obese and hypertensive rats: suppressing effects of EGCG on the development of liver lesions.
Topics: Angiotensin II; Animals; Anticarcinogenic Agents; Catechin; Fatty Liver; Gene Expression; Hypertension; Interleukin-6; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Peptidyl-Dipeptidase A; Precancerous Conditions; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Tumor Necrosis Factor-alpha | 2014 |
Intravital Förster resonance energy transfer imaging reveals elevated [Ca2+]i and enhanced sympathetic tone in femoral arteries of angiotensin II-infused hypertensive biosensor mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biosensing Techniques; Calcium; Calcium Signaling; Calmodulin; Femoral Artery; Fluorescence Resonance Energy Transfer; Hexamethonium; Hypertension; Infusions, Intravenous; Losartan; Mice; Muscle, Smooth, Vascular; Prazosin; Sympathetic Nervous System; Vasoconstriction | 2013 |
Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Loop of Henle; Male; Ouabain; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase | 2013 |
NADPH oxidases mediate a cellular "memory" of angiotensin II stress in hypertensive cardiac hypertrophy.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cells, Cultured; Hypertension; Male; Mice, Inbred C57BL; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2013 |
Stimulation of angiotensin type 1A receptors on catecholaminergic cells contributes to angiotensin-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Catecholamines; Hypertension; Mice; Mice, Knockout; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Subfornical Organ; Sympathetic Nervous System | 2013 |
COX-1-derived PGE2 and PGE2 type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca(2+) influx in the subfornical organ.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Hypertension; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Neurons; Phospholipases A2; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Prostaglandin E, EP1 Subtype; Subfornical Organ | 2013 |
Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Ganglionic Blockers; Hypertension; Ketoprofen; Male; Membrane Proteins; Norepinephrine; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sulfonamides; Sympathetic Nervous System; Time Factors | 2013 |
Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Autonomic Nervous System; Baroreflex; Blood Pressure; Brain; Desoxycorticosterone Acetate; Disease Models, Animal; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA Interference; Time Factors | 2013 |
A novel heart failure mice model of hypertensive heart disease by angiotensin II infusion, nephrectomy, and salt loading.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Cells, Cultured; Disease Models, Animal; Disease Progression; Fibrosis; Gene Expression Regulation; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Myocardium; Nephrectomy; Neuropeptides; Oxidative Stress; Pulmonary Edema; rac1 GTP-Binding Protein; Rats; Rats, Wistar; Sodium Chloride, Dietary; Time Factors; Ventricular Function, Left | 2013 |
Subservient relationship of the peripheral second systolic pressure peak to the central hemodynamic parameters is preserved, irrespective of atherosclerosis progression in hypercholesterolemic rabbits.
Topics: Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Disease Progression; Hemodynamics; Hypercholesterolemia; Hypertension; Male; Nitroprusside; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 2014 |
Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension.
Topics: Angiotensin II; Animals; CSK Tyrosine-Protein Kinase; Cyclic N-Oxides; Cytoplasm; Disease Models, Animal; Electron Transport; Endothelial Cells; Gene Silencing; Humans; Hydrogen Peroxide; Hypertension; Malates; Membrane Glycoproteins; Mice; Mice, Knockout; Mitochondria, Heart; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Protein Isoforms; Protein Transport; Reactive Oxygen Species; RNA Interference; src-Family Kinases; Superoxides | 2014 |
ELISA examining urinary angiotensinogen as a potential indicator of intrarenal renin-angiotensin system (RAS) activity: a clinical study of 128 chronic kidney disease patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensinogen; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regression Analysis; Renal Insufficiency, Chronic; Renin-Angiotensin System; Young Adult | 2013 |
Angiotensin-II induced hypertension and renovascular remodelling in tissue inhibitor of metalloproteinase 2 knockout mice.
Topics: Angiotensin II; Animals; Arterial Pressure; Blood Pressure; Collagen; Elastin; Hypertension; Kidney; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases | 2013 |
Combined antihypertensive effect of luteolin and buddleoside enriched extracts in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Drug Therapy, Combination; Endothelins; Epoprostenol; Glycosides; Hypertension; Luteolin; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Renin; Thromboxane B2 | 2013 |
Telmisartan delays myocardial fibrosis in rats with hypertensive left ventricular hypertrophy by TGF-β1/Smad signal pathway.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Collagen; Echocardiography; Fibrosis; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Telmisartan; Transforming Growth Factor beta1 | 2014 |
Paraventricular nucleus control of blood pressure in two-kidney, one-clip rats: effects of exercise training and resting blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Kidney; Male; Paraventricular Hypothalamic Nucleus; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Rest; Surgical Instruments; Sympathetic Nervous System | 2013 |
The 14q32 microRNA-487b targets the antiapoptotic insulin receptor substrate 1 in hypertension-induced remodeling of the aorta.
Topics: Angiotensin II; Animals; Aorta; Apoptosis; Blotting, Western; Cell Proliferation; Cell Survival; Female; Fibroblasts; Glucose; Humans; Hypertension; Immunohistochemistry; Insulin Receptor Substrate Proteins; Luciferases; MicroRNAs; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tumor Cells, Cultured; Umbilical Cord | 2013 |
Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.
Topics: Aging; Angiotensin II; Animals; Calcium; Calcium Signaling; Hydroxyeicosatetraenoic Acids; Hypertension; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Mice; Mice, Inbred C57BL; Middle Cerebral Artery; Muscle Contraction; Muscle, Smooth, Vascular; TRPC Cation Channels; Vasoconstriction | 2013 |
A mechanism underlying hypertensive occurrence in the metabolic syndrome: cooperative effect of oxidative stress and calcium accumulation in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cell Line; Diet, High-Fat; Hypertension; Male; Metabolic Syndrome; Mitochondria, Muscle; Muscle Contraction; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Vasoconstriction | 2014 |
Discharge of RVLM vasomotor neurons is not increased in anesthetized angiotensin II-salt hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Medulla Oblongata; Neurons; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sympathetic Nervous System | 2013 |
Comparison of extracts from cooked and raw lentil in antagonizing angiotensin II-induced hypertension and cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Hypertension; Lens Plant; Male; Myocytes, Cardiac; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2013 |
Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading.
Topics: Albuminuria; Amides; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cytoprotection; Disease Models, Animal; Disease Progression; Down-Regulation; Fumarates; Humans; Hydralazine; Hypertension; Kidney; Kidney Diseases; Mice; Mice, Transgenic; Ramipril; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2014 |
The protective effect of Liu-Wei-Di-Huang-Fang in salt-sensitive hypertension rats.
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Insulin; Male; Rats; Rats, Sprague-Dawley; Renin; Sodium Chloride, Dietary | 2014 |
Activation of angiotensin II type 1 receptor-associated protein exerts an inhibitory effect on vascular hypertrophy and oxidative stress in angiotensin II-mediated hypertension.
Topics: Adaptor Proteins, Signal Transducing; Aldehydes; Angiotensin II; Animals; Aorta; Cells, Cultured; Cytochrome b Group; Disease Models, Animal; Hypertension; Hypertrophy; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection | 2013 |
Increased nitric oxide bioavailability in adult GRK2 hemizygous mice protects against angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Female; G-Protein-Coupled Receptor Kinase 2; Hemizygote; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2014 |
Interplay between sodium and calcium regulatory hormones: a clinically relevant research field.
Topics: Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Parathyroid Hormone; Renin-Angiotensin System; Spironolactone | 2014 |
Bortezomib, a proteasome inhibitor, attenuates angiotensin II-induced hypertension and aortic remodeling in rats.
Topics: Angiotensin II; Animals; Aorta; Boronic Acids; Bortezomib; Cell Proliferation; Extracellular Matrix; Gene Expression Regulation; Hypertension; Male; Proteasome Inhibitors; Pyrazines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2013 |
Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na⁺-HCO₃⁻ cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: role of the renin-angiotensin system.
Topics: Ammonium Compounds; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Bicarbonates; Cardiomegaly; Disease Models, Animal; Down-Regulation; Endosomes; Hydrogen-Ion Concentration; Hyperkalemia; Hypertension; Losartan; Male; Myocytes, Cardiac; Potassium; Protein Transport; Rats; Rats, Inbred SHR; Rats, Wistar; Renin-Angiotensin System; Sarcolemma; Sodium-Bicarbonate Symporters; Time Factors | 2014 |
Enhanced expression and activity of Nox2 and Nox4 in the macula densa in ANG II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Cell Line; Hypertension; Isoenzymes; Juxtaglomerular Apparatus; Kidney Tubules, Distal; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; RNA, Messenger; Superoxides | 2014 |
Ang II-salt hypertension depends on neuronal activity in the hypothalamic paraventricular nucleus but not on local actions of tumor necrosis factor-α.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; GABA-A Receptor Agonists; Hypertension; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha | 2014 |
The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Aorta; Blood Pressure; Blood Vessels; Cells, Cultured; Female; GTPase-Activating Proteins; Humans; Hypertension; In Vitro Techniques; Male; Mice; Mice, Mutant Strains; Molecular Sequence Data; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; Phosphorylation; Rats; rhoA GTP-Binding Protein | 2013 |
Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Apoptosis; Blood Pressure; Brain; Hypertension; Losartan; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Prehypertension; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Stroke; Superoxide Dismutase; Time Factors | 2014 |
COX2 inhibition during nephrogenic period induces ANG II hypertension and sex-dependent changes in renal function during aging.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Female; Glomerular Filtration Rate; Hypertension; Kidney; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2014 |
Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.
Topics: Angiotensin II; Animals; Cardiomegaly; Chemokine CCL2; Enalaprilat; gamma-Aminobutyric Acid; Glutamic Acid; Heart; Hypertension; Interleukin-10; Interleukin-1beta; Interleukin-6; Kidney; Losartan; Male; Neurotransmitter Agents; Norepinephrine; Organ Size; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2014 |
Circulating angiotensin II gains access to the hypothalamus and brain stem during hypertension via breakdown of the blood-brain barrier.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain Stem; Disease Models, Animal; Hypertension; Hypothalamus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 2014 |
Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aortic Diseases; CD4 Antigens; CD8 Antigens; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Fibroblasts; Homeodomain Proteins; Hypertension; Inflammation; Interleukin-17; Male; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Stress, Mechanical; T-Lymphocytes; Vascular Stiffness; Vasculitis; Vasoconstrictor Agents | 2014 |
Overexpression of SIRT1 in vascular smooth muscle cells attenuates angiotensin II-induced vascular remodeling and hypertension in mice.
Topics: Angiotensin II; Animals; Aorta; Epigenesis, Genetic; Gene Expression; Hypertension; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Reactive Oxygen Species; Sirtuin 1; Vasculitis | 2014 |
Antihypertensive mechanism of lactoferrin-derived peptides: angiotensin receptor blocking effect.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Hypertension; Lactoferrin; Male; Molecular Weight; Peptides; Rabbits; Receptor, Angiotensin, Type 1; Vasoconstriction | 2014 |
Increased level of p63RhoGEF and RhoA/Rho kinase activity in hypertensive patients.
Topics: Adult; Angiotensin II; Bartter Syndrome; Blood Pressure; Case-Control Studies; Female; Gitelman Syndrome; Humans; Hypertension; Leukocytes, Mononuclear; Male; Middle Aged; Myosin-Light-Chain Phosphatase; Phosphorylation; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Solute Carrier Family 12, Member 3 | 2014 |
Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone Acetate; Hypertension; Interleukin-17; Kidney Diseases; Mice; Mice, Inbred C57BL; Signal Transduction | 2014 |
Fructose stimulates Na/H exchange activity and sensitizes the proximal tubule to angiotensin II.
Topics: Angiotensin II; Animals; Biological Transport; Disease Models, Animal; Fructose; Hydrogen-Ion Concentration; Hypertension; Kidney Tubules, Proximal; Rats; Sodium-Hydrogen Exchangers; Sweetening Agents | 2014 |
M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics.
Topics: Aldosterone; Angiotensin II; Animals; Arterial Pressure; Atrial Natriuretic Factor; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Enzyme Activation; Enzyme Activators; Guanylate Cyclase; Heart Failure; Hypertension; Male; Natriuresis; Nitroglycerin; Pulmonary Wedge Pressure; Receptors, Cytoplasmic and Nuclear; Renal Circulation; Soluble Guanylyl Cyclase; Time Factors | 2014 |
Folic acid mitigates angiotensin-II-induced blood pressure and renal remodeling.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Collagen; Drinking; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Hypertension; Kidney; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; RNA, Messenger; Tissue Inhibitor of Metalloproteinases | 2013 |
Regulatory networks and complex interactions between the insulin and angiotensin II signalling systems: models and implications for hypertension and diabetes.
Topics: Angiotensin II; Diabetes Mellitus; Feedback, Physiological; Humans; Hypertension; Insulin; Models, Biological; Receptor Cross-Talk; Renin-Angiotensin System; Signal Transduction; Vasodilation | 2013 |
Altered reactivity of resistance vasculature contributes to hypertension in elastin insufficiency.
Topics: Angiotensin II; Animals; Arterial Pressure; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Elastin; Endothelium, Vascular; Genetic Predisposition to Disease; Haploinsufficiency; Hemizygote; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 2; rho-Associated Kinases; Signal Transduction; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2014 |
Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Blood Pressure; Cell Size; Diabetes Mellitus, Type 2; Dobutamine; Gene Expression; Glycation End Products, Advanced; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Myocardium; Myocytes, Cardiac; Time Factors; Ultrasonography; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Atg5 deficiency-mediated mitophagy aggravates cardiac inflammation and injury in response to angiotensin II.
Topics: Angiotensin II; Animals; Autophagy-Related Protein 5; Heart Injuries; Humans; Hypertension; Inflammation; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mitophagy; Reactive Oxygen Species | 2014 |
Antagonist of C5aR prevents cardiac remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Agents; Collagen; Connective Tissue Growth Factor; Cytokines; Disease Models, Animal; Fibrosis; Hypertension; Mice, Inbred C57BL; Myocardium; Peptides, Cyclic; Receptor, Anaphylatoxin C5a; RNA, Messenger; Time Factors; Transforming Growth Factor beta1; Ventricular Remodeling | 2014 |
Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertension.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Autocrine Communication; Disease Models, Animal; Fibrosis; Hypertension; Kidney; Male; Myocardium; Paracrine Communication; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Ventricular Remodeling | 2014 |
Angiotensin-converting enzyme 2-independent action of presumed angiotensin-converting enzyme 2 activators: studies in vivo, ex vivo, and in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diminazene; Disease Models, Animal; Glutamyl Aminopeptidase; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Xanthones | 2014 |
Aqueous extract of dioscorea opposita thunb. normalizes the hypertension in 2K1C hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Captopril; China; Dioscorea; Drugs, Chinese Herbal; Endothelin-1; Heart; Hypertension; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Kidney; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Rats, Sprague-Dawley; Rats, Wistar; Superoxide Dismutase | 2014 |
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Cardiovascular Diseases; Disease Models, Animal; Echocardiography; Endothelium, Vascular; Heart Ventricles; Hemodynamics; Hypertension; Imidazoles; Male; Oxidative Stress; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley | 2014 |
Adiponectin expression protects against angiotensin II-mediated inflammation and accelerated atherosclerosis.
Topics: Adiponectin; Angiotensin II; Animals; Apolipoproteins; Atherosclerosis; Blood Pressure; Cholesterol; Disease Models, Animal; Gene Expression; Hypertension; Inflammation; Liver; Macrophages; Male; Mice; Mice, Knockout; Protein Multimerization; Protein Transport; Receptors, Adiponectin; Receptors, LDL; Receptors, Scavenger | 2014 |
Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Epoxide Hydrolases; Female; Hypertension; Nephrectomy; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renal Insufficiency, Chronic; Survival Rate | 2014 |
Phenotype-genotype analysis in two Chinese families with Liddle syndrome.
Topics: Angiotensin II; Asian People; Cardiovascular Diseases; Death, Sudden; Epithelial Sodium Channels; Exons; Female; Genetic Association Studies; Humans; Hypertension; Liddle Syndrome; Male; Mutation; Pedigree; Potassium | 2014 |
Aliskiren limits abdominal aortic aneurysm, ventricular hypertrophy and atherosclerosis in an apolipoprotein-E-deficient mouse model.
Topics: Amides; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Fumarates; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; Mice, Knockout | 2014 |
Clopidogrel preserves whole kidney autoregulatory behavior in ANG II-induced hypertension.
Topics: Angiotensin II; Animals; Clopidogrel; Hypertension; Kidney; Male; Purinergic P2Y Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y12; Renal Circulation; Thromboxane B2; Ticlopidine | 2014 |
Effects of a domain-selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Cardiomegaly; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Hypertension; Hypertrophy; Kidney; Lisinopril; Mice; Mice, Transgenic | 2014 |
An ongoing role of α-calcitonin gene-related peptide as part of a protective network against hypertension, vascular hypertrophy, and oxidative stress.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Endothelins; Hypertension; Hypertrophy; Mesentery; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Signal Transduction; Vasodilation | 2014 |
Selective inhibition of angiotensin receptor signaling through Erk1/2 pathway by a novel peptide.
Topics: Angiotensin II; Animals; Blood Pressure; Drinking; Female; Hypertension; Male; MAP Kinase Signaling System; Oligopeptides; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 2014 |
Low K⁺ current in arterial myocytes with impaired K⁺-vasodilation and its recovery by exercise in hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Hypertension; Male; Membrane Potentials; Muscle Cells; Physical Conditioning, Animal; Potassium; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Vasodilation | 2014 |
miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling.
Topics: Angiotensin II; Animals; Disease Models, Animal; Endomyocardial Fibrosis; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Hypertension; Mice; MicroRNAs; Molecular Targeted Therapy; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta | 2014 |
Ginsenoside Rb3 attenuates oxidative stress and preserves endothelial function in renal arteries from hypertensive rats.
Topics: Adult; Aged; Angiotensin II; Animals; Dose-Response Relationship, Drug; Endothelium, Vascular; Ginsenosides; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Middle Aged; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Panax; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Renal Artery; Vasoconstriction | 2014 |
Inhibition of reactive oxygen species in hypothalamic paraventricular nucleus attenuates the renin-angiotensin system and proinflammatory cytokines in hypertension.
Topics: Angiotensin II; Animals; Antioxidants; Arterial Pressure; Cyclic N-Oxides; Hypertension; Interleukin-1beta; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin-Angiotensin System; Spin Labels | 2014 |
Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1.
Topics: Angiotensin II; Animals; Blood Pressure; Carboxypeptidases; Cathepsin A; Cells, Cultured; Endothelin-1; Hemodynamics; Humans; Hypertension; Mice; Vasoconstriction | 2014 |
The requirement of CD8+ T cells to initiate and augment acute cardiac inflammatory response to high blood pressure.
Topics: Adoptive Transfer; Angiotensin II; Animals; CD8 Antigens; CD8-Positive T-Lymphocytes; Cytokines; Fibrosis; Flow Cytometry; Hypertension; Inflammation Mediators; Lymphocyte Activation; Macrophages; Mice; Mice, 129 Strain; Mice, Knockout; Mice, Transgenic; Myocardium; Receptors, Antigen, T-Cell; Reverse Transcriptase Polymerase Chain Reaction | 2014 |
As drug target reemerges, the question is to block or stimulate it.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Clinical Trials as Topic; Drug Design; Drug Industry; Humans; Hypertension; Pulmonary Fibrosis; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2014 |
Can serial monitoring of serum Vascular Endothelial Growth Factor (VEGF), Nitric Oxide (NO), and Angiotensin II (ANGII) levels have predictive role during Bevacizumab treatment?
Topics: Adult; Aged; Angiotensin II; Antibodies, Monoclonal, Humanized; Bevacizumab; Colorectal Neoplasms; Demography; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Nitric Oxide; Prognosis; Vascular Endothelial Growth Factor A | 2014 |
Female spontaneously hypertensive rats are more dependent on ANG (1-7) to mediate effects of low-dose AT1 receptor blockade than males.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Adhesion Molecules; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Male; Membrane Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sex Factors; Tetrazoles | 2014 |
Renal molecular mechanisms underlying altered Na+ handling and genesis of hypertension during adulthood in prenatally undernourished rats.
Topics: Adenosine Triphosphatases; alpha-Tocopherol; Angiotensin II; Animals; Cation Transport Proteins; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Diet, Protein-Restricted; Down-Regulation; Female; Glutathione; Hypertension; Kidney Tubules, Proximal; Lipid Peroxidation; Male; Malnutrition; NADPH Oxidases; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Angiotensin; Sodium, Dietary | 2014 |
Urinary angiotensinogen as a potential biomarker of intrarenal renin-angiotensin system activity in Chinese chronic kidney disease patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Angiotensinogen; Asian People; Biomarkers; China; Collagen Type IV; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Receptors, Angiotensin; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Young Adult | 2015 |
Central blockade of TLR4 improves cardiac function and attenuates myocardial inflammation in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Cardiomegaly; Hypertension; Interleukin-1beta; Male; Myocarditis; NF-kappa B; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
Selective alpha(1)-adrenoceptor blockade prevents fructose-induced hypertension.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Fructose; Hypertension; Insulin Resistance; Male; Norepinephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Uric Acid | 2014 |
The ameliorating effects of long-term electroacupuncture on cardiovascular remodeling in spontaneously hypertensive rats.
Topics: Acupuncture Points; Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Collagen; Electroacupuncture; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Hypertension; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptor, Angiotensin, Type 1; Vascular Remodeling | 2014 |
An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Docosahexaenoic Acids; Epoxide Hydrolases; Fatty Acids, Omega-3; Hypertension; Male; Mice; Phenylurea Compounds; Piperidines | 2014 |
CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Brain-Derived Neurotrophic Factor; Central Nervous System; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Hexamethonium; Hypertension; Male; Neuronal Plasticity; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2014 |
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.
Topics: Adaptor Proteins, Signal Transducing; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Epithelial Sodium Channels; Gene Deletion; Hydrogen-Ion Concentration; Hypertension; Kidney Tubules, Distal; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Renal Reabsorption; RNA, Messenger; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Urinalysis; Vasoconstrictor Agents | 2014 |
Relaxin does not improve Angiotensin II-induced target-organ damage.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Humans; Hypertension; Male; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Recombinant Proteins; Relaxin; Renin | 2014 |
S100a8/a9 released by CD11b+Gr1+ neutrophils activates cardiac fibroblasts to initiate angiotensin II-Induced cardiac inflammation and injury.
Topics: Angiotensin II; Animals; Animals, Newborn; Antibodies; Antigens, Ly; Calgranulin A; Calgranulin B; CD11b Antigen; Cells, Cultured; Cytokines; Fibroblasts; Hypertension; Immunohistochemistry; Inflammation; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Neutrophils; Oligonucleotide Array Sequence Analysis; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptor 4; Transcriptome | 2014 |
Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis.
Topics: Angiotensin II; Animals; Animals, Newborn; Arachidonic Acids; Biomarkers; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Epoxide Hydrolases; Fibrosis; Hypertension; Interleukin-6; Male; Metabolome; Mice; Mice, Inbred C57BL; Myocardium; Myofibroblasts; Ventricular Remodeling | 2014 |
Effect of postnatal maternal protein intake on prenatal programming of hypertension.
Topics: Albuminuria; Angiotensin II; Animal Nutritional Physiological Phenomena; Animals; Blood Pressure; Diet, Protein-Restricted; Dietary Proteins; Female; Hypertension; Kidney Glomerulus; Lactation; Maternal Nutritional Physiological Phenomena; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Solute Carrier Family 12, Member 1; Time Factors | 2014 |
Complement 5a receptor mediates angiotensin II-induced cardiac inflammation and remodeling.
Topics: Angiotensin II; Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Complement Activation; Humans; Hypertension; Macrophages; Mice; Mice, Inbred C57BL; Myocarditis; Receptor, Anaphylatoxin C5a; Receptors, Complement; Ventricular Remodeling | 2014 |
Enhanced expression of Gqα and PLC-β1 proteins contributes to vascular smooth muscle cell hypertrophy in SHR: role of endogenous angiotensin II and endothelin-1.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Phospholipase C beta; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; RNA Interference; Signal Transduction; Transcription Factor AP-1; Transfection; Up-Regulation | 2014 |
Regulation of apelin and its receptor expression in adipose tissues of obesity rats with hypertension and cultured 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Adipose Tissue; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apelin; Apelin Receptors; Gene Expression; Gene Expression Regulation; Hypertension; Imidazoles; Intercellular Signaling Peptides and Proteins; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Obesity; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Tetrazoles | 2014 |
Importance of estrogen metabolites.
Topics: Angiotensin II; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Estradiol; Female; Hypertension | 2014 |
Estrogen metabolism by cytochrome P450 1B1 modulates the hypertensive effect of angiotensin II in female mice.
Topics: Angiotensin II; Animals; Aryl Hydrocarbon Hydroxylases; Blood Pressure; Cytochrome P-450 CYP1B1; Estradiol; Female; Heart; Hypertension; Mice; Mice, Knockout; Myocardium; Oxidative Stress | 2014 |
Angiotensin II and 1-7 during aging in Metabolic Syndrome rats. Expression of AT1, AT2 and Mas receptors in abdominal white adipose tissue.
Topics: Adipose Tissue, White; Aging; Angiotensin I; Angiotensin II; Animals; Gene Expression Regulation; Humans; Hypertension; Metabolic Syndrome; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2014 |
Calcitriol supplementation improves endothelium-dependent vasodilation in rat hypertensive renal injury.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Calcitriol; Dietary Supplements; Dinoprost; Disease Models, Animal; Endothelium, Vascular; Glucuronidase; Hypertension; Irbesartan; Kidney; Kidney Diseases; Klotho Proteins; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Tetrazoles; Vasodilation; Vitamins | 2014 |
Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cellulase; Diet, Mediterranean; Disease Models, Animal; Epoxide Hydrolases; Fatty Acids; Gene Knock-In Techniques; Hypertension; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitrates; Nitrites; Sulfhydryl Compounds; Vasoconstrictor Agents; Vasodilation | 2014 |
CXCR6 plays a critical role in angiotensin II-induced renal injury and fibrosis.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Bone Marrow Transplantation; Cytokines; Disease Models, Animal; Fibrosis; Green Fluorescent Proteins; Hypertension; Inflammation Mediators; Kidney; Kidney Diseases; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myofibroblasts; Receptors, CXCR; Receptors, CXCR6; Signal Transduction; T-Lymphocytes; Time Factors | 2014 |
Estrogen regulation of the brain renin-angiotensin system in protection against angiotensin II-induced sensitization of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Brain; Disease Models, Animal; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression Regulation; Hypertension; Infusions, Intraventricular; Male; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger; Sex Factors; Telemetry; Time Factors | 2014 |
A method for noninvasive longitudinal measurements of [Ca2+] in arterioles of hypertensive optical biosensor mice.
Topics: Angiotensin II; Animals; Arterial Pressure; Arterioles; Biosensing Techniques; Calcium; Calcium Signaling; Disease Models, Animal; Fluorescence Resonance Energy Transfer; Hypertension; Mice; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Skin; Sodium Chloride, Dietary; Time Factors | 2014 |
Alkaloids of Nitraria sibirica Pall. decrease hypertension and albuminuria in angiotensin II-salt hypertension.
Topics: Albuminuria; Alkaloids; Angiotensin II; Animals; Blood Pressure; Chemokine CCL2; Drugs, Chinese Herbal; Humans; Hypertension; Magnoliopsida; Male; Mice; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2014 |
γδT Cell-derived interleukin-17A via an interleukin-1β-dependent mechanism mediates cardiac injury and fibrosis in hypertension.
Topics: Angiotensin II; Animals; Fibrosis; Hypertension; Interleukin-17; Interleukin-1beta; Interleukin-6; Mice; Myocardium; T-Lymphocytes; Transforming Growth Factor beta | 2014 |
Class A scavenger receptor deficiency augments angiotensin II-induced vascular remodeling.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Vessels; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Coculture Techniques; Crosses, Genetic; Disease Models, Animal; Hypertension; Infusions, Intravenous; Macrophages; Male; Mice; Mice, 129 Strain; Mice, Inbred ICR; Mice, Knockout; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Scavenger Receptors, Class A; Transplantation Chimera | 2014 |
Sex differences in T-lymphocyte tissue infiltration and development of angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Heart Rate; Homeodomain Proteins; Hypertension; Male; Mice; Mice, Knockout; Sex Characteristics; T-Lymphocytes | 2014 |
Neuronal uptake of nanoformulated superoxide dismutase and attenuation of angiotensin II-dependent hypertension after central administration.
Topics: Angiotensin II; Animals; Antioxidants; Cells, Cultured; Central Nervous System; Drug Delivery Systems; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Heart Failure; Hypertension; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Polyethylene Glycols; Polymers; Superoxide Dismutase; Superoxides | 2014 |
Sex-specific T-cell regulation of angiotensin II-dependent hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Female; Heart Rate; Homeodomain Proteins; Hypertension; Interleukin-10; Interleukin-17; Male; Mice; Mice, Knockout; Sex Factors; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2014 |
Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hydrogen Sulfide; Hypertension; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sulfides; Thiosulfates | 2015 |
Resveratrol prevents AngII-induced hypertension via AMPK activation and RhoA/ROCK suppression in mice.
Topics: Adenylate Kinase; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Resveratrol; rho-Associated Kinases; rhoA GTP-Binding Protein; Stilbenes | 2014 |
Knockdown of mineralocorticoid or angiotensin II type 1 receptor gene expression in the paraventricular nucleus prevents angiotensin II hypertension in rats.
Topics: Angiotensin II; Animals; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Mineralocorticoid | 2014 |
Renal arteriolar injury by salt intake contributes to salt memory for the development of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Blood Pressure; Blotting, Western; Calcium Channel Blockers; Epithelial Sodium Channels; Gene Expression; Hypertension; Kidney; Kidney Glomerulus; Kidney Transplantation; Male; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride, Dietary; Time Factors | 2014 |
Dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Hypertension; Male; Peptide Fragments | 2014 |
Reply: dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Hypertension; Male; Peptide Fragments | 2014 |
AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.
Topics: A Kinase Anchor Proteins; Angiotensin II; Animals; Calcium Signaling; Disease Models, Animal; Endothelium, Vascular; Hypertension; Ion Channel Gating; Mice; Mice, Knockout; TRPV Cation Channels; Vasoconstrictor Agents; Vasodilation | 2014 |
Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition.
Topics: Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rate; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Renin; Symporters | 2014 |
[Effect of tanshinone II(A) on expression of different components in renin-angiotensin system of left ventricles of hypertensive rats].
Topics: Abietanes; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Heart Ventricles; Humans; Hypertension; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 2014 |
Angiotensin-(1-7) prevents angiotensin II-induced fibrosis in cremaster microvessels.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Chronic Disease; Connective Tissue Growth Factor; Dual Specificity Phosphatase 1; Fibrosis; Hypertension; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Rats; Rats, Inbred Lew; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Vasoconstrictor Agents | 2015 |
Oxidative status in the macula densa modulates tubuloglomerular feedback responsiveness in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney Glomerulus; Kidney Tubules; Mice, Inbred C57BL; Nephrons; Nitric Oxide; Oxidative Stress; Vasoconstrictor Agents | 2015 |
Toll-like receptor 4 upregulation by angiotensin II contributes to hypertension and vascular dysfunction through reactive oxygen species production.
Topics: Acetylcholine; Angiotensin II; Animals; Antioxidants; Aorta; Blood Pressure; Cell Movement; Cell Proliferation; Endothelium, Vascular; Gene Expression Regulation; Heart Rate; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phenylephrine; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; Superoxides; Toll-Like Receptor 4; Up-Regulation; Vasoconstriction; Vasodilation | 2014 |
Hydrogen sulfide treatment reduces blood pressure and oxidative stress in angiotensin II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cystathionine gamma-Lyase; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Hydrogen Sulfide; Hypertension; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Superoxides | 2015 |
Oral administration of bisphenol A induces high blood pressure through angiotensin II/CaMKII-dependent uncoupling of eNOS.
Topics: Administration, Oral; Angiotensin II; Animals; Benzhydryl Compounds; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Endothelium, Vascular; Hypertension; Mice; Nitric Oxide Synthase Type III; Phenols; Phosphorylation | 2014 |
Novel mechanism of intra‑renal angiotensin II-induced sodium/proton exchanger 3 expression by losartan in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Female; Gene Expression; Hypertension; Immediate-Early Proteins; Kidney; Losartan; Male; Protein Serine-Threonine Kinases; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Transcriptional Activation | 2014 |
Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Arterial Pressure; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Losartan; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Vasoconstriction | 2014 |
Angiotensin induces a pressor regulating role for collecting duct renin.
Topics: Angiotensin II; Animals; Female; Hypertension; Kidney Tubules, Collecting; Male; Renin | 2014 |
Collecting duct-specific knockout of renin attenuates angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Epithelial Sodium Channels; Female; Hypertension; Kidney; Kidney Tubules, Collecting; Male; Mice, Inbred C57BL; Mice, Knockout; Renin; RNA, Messenger; Sodium Chloride, Dietary | 2014 |
Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.
Topics: Angiotensin II; Animals; Cardiomegaly; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic Nucleotide Phosphodiesterases, Type 5; Fibrosis; Genetic Markers; Hypertension; Mice; Muscle, Smooth; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasoconstrictor Agents | 2014 |
Renal medullary cyclooxygenase-2 and (pro)renin receptor expression during angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Hypertension; Kidney Cortex; Kidney Medulla; Male; Prorenin Receptor; Prostaglandins E; Rats, Sprague-Dawley; Receptors, Cell Surface | 2014 |
Exogenous hydrogen sulfide causes different hemodynamic effects in normotensive and hypertensive rats via neurogenic mechanisms.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Heart Rate; Hydrogen Sulfide; Hypertension; Infusions, Intraventricular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfides | 2014 |
Tumor necrosis factor-α produced in the kidney contributes to angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Renal Insufficiency, Chronic; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2014 |
Combined suppression of the intrarenal and circulating vasoconstrictor renin-ACE-ANG II axis and augmentation of the vasodilator ACE2-ANG 1-7-Mas axis attenuates the systemic hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Topics: Age Factors; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Hypoxia; Kidney; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation | 2015 |
Elimination of vitamin D receptor in vascular endothelial cells alters vascular function.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Blotting, Western; Disease Models, Animal; DNA; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Humans; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Natriuretic Peptide, Brain; Rats; Receptors, Calcitriol; Vasodilation | 2014 |
RAAS and stress markers in acute ischemic stroke: preliminary findings.
Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Animals; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Stroke | 2015 |
Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cytochrome P-450 CYP1A1; Epoxide Hydrolases; Hypertension; Indoles; Kidney; Male; Mice; Natriuresis; Rats; Rats, Inbred F344; Rats, Transgenic; Renin; Renin-Angiotensin System | 2014 |
Angiotensin II mediates angiotensin converting enzyme type 2 internalization and degradation through an angiotensin II type I receptor-dependent mechanism.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1 | 2014 |
Endothelial AT₁ and AT₂ pathways in aortic responses to angiotensin II after stress and ethanol consumption in rats.
Topics: Alcohol Drinking; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antioxidants; Blood Pressure; Corticosterone; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Ethanol; Hypertension; Male; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Restraint, Physical; Risk Factors; Signal Transduction; Stress, Psychological; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2014 |
Angiotensin type 1A receptor expression in C1 neurons of the rostral ventrolateral medulla contributes to the development of angiotensin-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Medulla Oblongata; Mice; Mice, Knockout; Neurons; Receptor, Angiotensin, Type 1 | 2014 |
DC isoketal-modified proteins activate T cells and promote hypertension.
Topics: Aged; Aldehydes; Angiotensin II; Animals; Antigen-Presenting Cells; B7-1 Antigen; B7-2 Antigen; Cell Proliferation; Cohort Studies; Dendritic Cells; Female; Gene Expression Regulation; Humans; Hypertension; Inflammation; Interleukin-17; Interleukin-1beta; Interleukin-23; Interleukin-6; Kidney; Lymphocyte Activation; Male; Mice; Mice, Transgenic; Middle Aged; Oxidative Stress; Oxygen; Superoxides; T-Lymphocytes | 2014 |
IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
Topics: Aging; Angiotensin II; Animals; Biomarkers; Blood-Brain Barrier; Cerebrovascular Circulation; Dementia; Disease Models, Animal; Encephalitis; Hippocampus; Homeostasis; Hypertension; Insulin-Like Growth Factor I; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Microglia; Middle Cerebral Artery; TRPC Cation Channels; Vasoconstrictor Agents | 2014 |
Oligoclonal CD8+ T cells play a critical role in the development of hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; CD8-Positive T-Lymphocytes; Disease Models, Animal; Endothelium, Vascular; Homeodomain Proteins; Hypertension; Kidney; Major Histocompatibility Complex; Male; Mice; Mice, Knockout; Oligoclonal Bands; Vascular Remodeling | 2014 |
Serine proteases as candidates for proteolytic processing of angiotensin-I converting enzyme.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Mesangial Cells; Peptidyl-Dipeptidase A; Protein Isoforms; Proteolysis; Rats; Serine Proteases | 2015 |
Chronic central nervous system MC3/4R blockade attenuates hypertension induced by nitric oxide synthase inhibition but not by angiotensin II infusion.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Infusions, Intravenous; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4 | 2015 |
Serelaxin reduces oxidative stress and asymmetric dimethylarginine in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Arginine; Arterial Pressure; Dinoprost; Disease Models, Animal; Down-Regulation; Humans; Hypertension; Injections, Subcutaneous; Kidney; Liver; Male; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Proteinuria; Rats, Sprague-Dawley; Recombinant Proteins; Relaxin; Thiobarbituric Acid Reactive Substances | 2014 |
Direct pro-inflammatory effects of prorenin on microglia.
Topics: Angiotensin II; Animals; Brain; Cell Line; Cells, Cultured; Cytokines; Disease Models, Animal; Gene Expression; Humans; Hypertension; Inflammation Mediators; Male; Mice; Mice, Transgenic; Microglia; Minocycline; NF-kappa B; ras Proteins; Rats; Rats, Inbred SHR; Renin | 2014 |
Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension.
Topics: Albumins; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Echocardiography; Fibrosis; Heart; Heart Rate; Hypertension; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Phenotype; Sodium Chloride, Dietary | 2015 |
A subpressor dose of angiotensin II elevates blood pressure in a normotensive rat model by oxidative stress.
Topics: Angiotensin II; Animals; Blood Pressure; Free Radicals; Glutathione Peroxidase; Hydrogen Peroxide; Hypertension; Male; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Vasoconstrictor Agents | 2015 |
Lack of renoprotective effect of chronic intravenous angiotensin-(1-7) or angiotensin-(2-10) in a rat model of focal segmental glomerulosclerosis.
Topics: Angiotensin I; Angiotensin II; Animals; Drug Administration Schedule; Glomerulosclerosis, Focal Segmental; HEK293 Cells; Humans; Hypertension; Injections, Intravenous; Male; Nephrectomy; Peptide Fragments; Podocytes; Radioligand Assay; Rats; Treatment Failure | 2014 |
Human aldosterone synthase gene polymorphism promotes miRNA binding and regulates gene expression.
Topics: Alleles; Angiotensin II; Blood Pressure; Cytochrome P-450 CYP11B2; Down-Regulation; Gene Expression Regulation; HEK293 Cells; Humans; Hypertension; MicroRNAs; Polymorphism, Genetic; Renin-Angiotensin System | 2014 |
Baicalein attenuates angiotensin II-induced cardiac remodeling via inhibition of AKT/mTOR, ERK1/2, NF-κB, and calcineurin signaling pathways in mice.
Topics: Angiotensin II; Animals; Calcineurin Inhibitors; Cytokines; Disease Models, Animal; Enzyme Activation; Fibrosis; Flavanones; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Inflammation Mediators; Lipoxygenase Inhibitors; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; NF-kappa B; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Ventricular Function, Left; Ventricular Remodeling | 2015 |
An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Bradykinin B1 Receptor Antagonists; Cells, Cultured; Drug Synergism; Hypertension; Hypertrophy; Kallikrein-Kinin System; Losartan; Male; Myocytes, Smooth Muscle; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Bradykinin B1; Renin-Angiotensin System; Superoxides | 2014 |
Constitutive activation of the renin-angiotensin system reduces visceral fat and improves glucose tolerance in mice.
Topics: Angiotensin II; Animals; Area Under Curve; Creatinine; Drinking; Energy Metabolism; Gene Expression Regulation; Glucose Tolerance Test; Homeostasis; Humans; Hypertension; Insulin; Insulin Secretion; Intra-Abdominal Fat; Kidney Function Tests; Kidney Tubules, Proximal; Mice, Inbred C57BL; Mice, Transgenic; Muscles; Organ Size; Phenotype; Ramipril; Renin-Angiotensin System | 2014 |
Lectin-like oxidized low-density lipoprotein receptor-1 regulates autophagy and Toll-like receptor 4 in the brain of hypertensive mice.
Topics: Angiotensin II; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Blood Pressure; Brain; Hypertension; Mice; NADPH Oxidases; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Scavenger Receptors, Class E; Toll-Like Receptor 4 | 2015 |
Benefical therapeutic effect of Chinese Herbal Xinji'erkang formula on hypertension-induced renal injury in the 2-kidney-1-clip hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Kidney; Kidney Diseases; Magnoliopsida; Male; Organ Size; Phytotherapy; Rats, Sprague-Dawley; Renal Artery; Surgical Instruments; Transforming Growth Factor beta1 | 2014 |
Pentoxifylline alleviates hypertension in metabolic syndrome: effect on low-grade inflammation and angiotensin system.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Inflammation; Male; Metabolic Syndrome; Pentoxifylline; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Vasodilator Agents | 2015 |
Intracerebroventricular infusion of the (Pro)renin receptor antagonist PRO20 attenuates deoxycorticosterone acetate-salt-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Binding, Competitive; Blood Pressure; Calcium; Captopril; Cell Line, Tumor; Desoxycorticosterone Acetate; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Hypothalamus; Infusions, Intraventricular; Ion Transport; Losartan; Mice; Mice, Inbred C57BL; Neuroblastoma; Peptide Fragments; Phosphorylation; Prorenin Receptor; Protein Processing, Post-Translational; Receptors, Cell Surface; Renin; Sodium Chloride; Vacuolar Proton-Translocating ATPases | 2015 |
Preventive effect of gomisin J from Schisandra chinensis on angiotensin II-induced hypertension via an increased nitric oxide bioavailability.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biological Availability; Blood Pressure; Cyclooctanes; Dioxoles; Disease Models, Animal; Hypertension; Lignans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Plant Extracts; Polycyclic Compounds; Reactive Oxygen Species; Schisandra; Treatment Outcome; Vasodilator Agents | 2015 |
A role for innate immunity in the development of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cytokines; Humans; Hypertension; Immunity, Innate; Inflammation; Interleukin-6; Mice; Muscle, Smooth, Vascular; Myeloid Differentiation Factor 88; NF-kappa B; Risk Factors; Signal Transduction; Toll-Like Receptor 4 | 2014 |
Pro-inflammatory cytokines in paraventricular nucleus mediate the cardiac sympathetic afferent reflex in hypertension.
Topics: Angiotensin II; Animals; Arterial Pressure; Bradykinin; Calcium Channel Agonists; Cytokines; Diterpenes; Hypertension; Interleukin-13; Interleukin-1beta; Interleukin-4; Kidney; Male; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats, Inbred SHR; Rats, Inbred WKY; Reflex; Sympathetic Nervous System; Tumor Necrosis Factor-alpha | 2014 |
Sodium thiosulfate attenuates angiotensin II-induced hypertension, proteinuria and renal damage.
Topics: Angiotensin II; Animals; Base Sequence; DNA Primers; Hypertension; Kidney; Proteinuria; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Thiosulfates | 2014 |
Reduction of prohibitin expression contributes to left ventricular hypertrophy via enhancement of mitochondrial reactive oxygen species formation in spontaneous hypertensive rats.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Gene Expression Regulation; Gene Knockdown Techniques; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Prohibitins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Repressor Proteins; Ventricular Function | 2015 |
Ultrafine carbon black attenuates the antihypertensive effect of captopril in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bronchoalveolar Lavage Fluid; Captopril; Heart; Heart Rate; Hypertension; Lung; Male; Particulate Matter; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Soot | 2014 |
Over-expression of copper/zinc superoxide dismutase in the median preoptic nucleus attenuates chronic angiotensin II-induced hypertension in the rat.
Topics: Adenoviridae; Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Hypothalamus; Male; Preoptic Area; Rats, Sprague-Dawley; Sodium; Superoxide Dismutase; Water | 2014 |
Trimethylamine-N-oxide: a carnitine-derived metabolite that prolongs the hypertensive effect of angiotensin II in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Hypertension; Male; Methylamines; Oxidants; Rats; Rats, Sprague-Dawley | 2014 |
Hemodynamic basis for the limited renal injury in rats with angiotensin II-induced hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hemodynamics; Hypertension; Kidney; Male; Rats, Sprague-Dawley; Renal Circulation | 2015 |
Elevated pressure causes endothelial dysfunction in mouse carotid arteries by increasing local angiotensin signaling.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Arteries; Endothelium, Vascular; Hydrazines; Hypertension; Indoles; Losartan; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Signal Transduction; Tetrazoles; Valine; Valsartan; Vasodilation | 2015 |
The effect of simvastatin and pravastatin on arterial blood pressure, baroreflex, vasoconstrictor, and hypertensive effects of angiotensin II in Sprague-Dawley rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Drug Synergism; Heart Rate; Hypertension; Male; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Vasoconstriction | 2014 |
Angiotensin-(1-7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Type 1; Fibrosis; Gene Expression Regulation; Histological Techniques; Hypertension; Immunohistochemistry; Injections, Subcutaneous; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Receptors, G-Protein-Coupled | 2015 |
Inhibitory effect of D3 dopamine receptor on migration of vascular smooth muscle cells induced by synergistic effect of angiotensin II and aldosterone.
Topics: Aldosterone; Angiotensin II; Aorta, Thoracic; Cell Movement; Cells, Cultured; Drug Synergism; Humans; Hypertension; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, Dopamine D3; Signal Transduction | 2015 |
Differential phenotypes of tissue-infiltrating T cells during angiotensin II-induced hypertension in mice.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Humans; Hypertension; Interleukin-17; Interleukin-4; Mice; Phenotype; Reactive Oxygen Species; T-Lymphocytes; Tumor Necrosis Factor-alpha; Vascular Diseases | 2014 |
Beneficial effects of simulated gastro-intestinal digests of fried egg and its fractions on blood pressure, plasma lipids and oxidative stress in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Egg White; Essential Hypertension; Humans; Hypertension; Nitric Oxide; Oxidative Stress; Protein Hydrolysates; Rats; Rats, Inbred SHR | 2014 |
Chronic ANG II infusion induces sex-specific increases in renal T cells in Sprague-Dawley rats.
Topics: Angiotensin II; Animals; Humans; Hypertension; Interleukin-10; Interleukin-17; Kidney; Male; Rats, Sprague-Dawley; Sex Characteristics; T-Lymphocytes | 2015 |
The angiogenic factor PlGF mediates a neuroimmune interaction in the spleen to allow the onset of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Ganglia, Sympathetic; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroimmunomodulation; Placenta Growth Factor; Pregnancy Proteins; RNA Interference; RNA, Small Interfering; Sirtuin 1; Spleen; T-Lymphocytes; Tissue Inhibitor of Metalloproteinase-3; Tumor Suppressor Protein p53 | 2014 |
Caveolin-1 prevents sustained angiotensin II-induced resistance artery constriction and obesity-induced high blood pressure.
Topics: Angiotensin II; Animals; Arteries; Caveolae; Caveolin 2; Cell Membrane; Hypertension; Male; Muscle, Smooth, Vascular; Obesity; Protein Binding; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2015 |
Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; DNA Damage; DNA Repair; Enzyme Activation; Eplerenone; Guanosine; Heart; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Spin Labels; Spironolactone; Tetrazoles | 2014 |
Genetic knockdown of estrogen receptor-alpha in the subfornical organ augments ANG II-induced hypertension in female mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Estrogen Receptor alpha; Female; Ganglionic Blockers; Gene Knockdown Techniques; Genotype; Heart Rate; Hypertension; Male; Mice, Knockout; Nestin; Phenotype; Subfornical Organ; Sympathetic Nervous System | 2015 |
GRK2 targeted knock-down results in spontaneous hypertension, and altered vascular GPCR signaling.
Topics: Angiotensin II; Animals; G-Protein-Coupled Receptor Kinase 2; Gene Knockdown Techniques; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; MAP Kinase Signaling System; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proto-Oncogene Proteins c-akt | 2015 |
Dexamethasone promotes hypertension by allele-specific regulation of the human angiotensinogen gene.
Topics: Alleles; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dexamethasone; Gene Expression; Genetic Predisposition to Disease; Glucocorticoids; Haplotypes; Humans; Hypertension; Immunoblotting; Male; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Superoxide Dismutase-1 | 2015 |
The association between BMP4 gene polymorphism and its serum level with the incidence of LVH in hypertensive patients.
Topics: Angiotensin II; Bone Morphogenetic Protein 4; C-Reactive Protein; Cystatin C; Essential Hypertension; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Hypertension; Hypertrophy, Left Ventricular; Incidence; Male; Middle Aged; Myocytes, Cardiac; Peptide Fragments; Polymorphism, Single Nucleotide; Procollagen; Protein Biosynthesis; RNA, Small Interfering; Transfection | 2015 |
Endocannabinoid-mediated modulation of Gq/11 protein-coupled receptor signaling-induced vasoconstriction and hypertension.
Topics: Angiotensin II; Animals; Aorta; Arachidonic Acids; Benzodioxoles; Calcium; Calcium Signaling; Dinoprost; Endocannabinoids; Gene Expression Regulation; Glycerides; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Lactones; Lipoprotein Lipase; Male; Mice; Mice, Knockout; Monoacylglycerol Lipases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Orlistat; Phenylephrine; Piperidines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Tissue Culture Techniques; Vasoconstriction | 2015 |
Deficiency of endothelium-specific transcription factor Sox17 induces intracranial aneurysm.
Topics: Adult; Aged; Angiotensin II; Animals; Aorta; Cells, Cultured; Cerebral Arteries; Cyclin-Dependent Kinase Inhibitor Proteins; Dilatation, Pathologic; Disease Models, Animal; Endothelium, Vascular; Female; HMGB Proteins; Humans; Hypertension; Intracranial Aneurysm; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myocytes, Smooth Muscle; Paracrine Communication; RNA Interference; SOXF Transcription Factors; Specific Pathogen-Free Organisms; Subarachnoid Hemorrhage; Transcription, Genetic; Up-Regulation; Veins | 2015 |
Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice.
Topics: Angiotensin II; Animals; Biological Transport; Blood Pressure; Disease Models, Animal; Epithelial Sodium Channels; Genotype; Hypertension; Interferon-gamma; Interleukin-17; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Mice, Knockout; Sodium; Sodium Chloride Symporters; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Solute Carrier Family 12, Member 1 | 2015 |
PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension.
Topics: Amiloride; Angiotensin II; Animals; Arteries; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Epithelial Sodium Channels; Female; Hypertension; Kidney; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases; Sodium; Sodium Chloride, Dietary | 2015 |
Vitamin D depletion aggravates hypertension and target-organ damage.
Topics: Acute-Phase Proteins; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Creatinine; Heart; Humans; Hypertension; Lipocalin-2; Lipocalins; Natriuretic Peptides; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Risk Factors; RNA, Messenger; Vitamin D; Vitamin D Deficiency | 2015 |
Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology.
Topics: Angiotensin II; Animals; Blood Pressure; Cytosol; Disease Models, Animal; Gene Expression Regulation; Group IV Phospholipases A2; Hypertension; Lipid Metabolism; Mice; Mice, Inbred BALB C; Myocardium; Oxidative Stress; Real-Time Polymerase Chain Reaction; RNA | 2015 |
Antihypertensive effect of mitochondria-targeted proxyl nitroxides.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Blood Pressure; Cell Line; Cyclic N-Oxides; Endothelial Cells; Humans; Hydrogen Peroxide; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mitochondria; Molecular Targeted Therapy; Organophosphorus Compounds; Piperidines; Superoxides | 2015 |
[Up-regulation of intrarenal renin-angiotensin system contributes to renal damage in high-salt induced hypertension rats].
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Male; Proteinuria; Rats; Rats, Inbred WKY; Real-Time Polymerase Chain Reaction; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Up-Regulation | 2015 |
Disruption of the cytochrome P-450 1B1 gene exacerbates renal dysfunction and damage associated with angiotensin II-induced hypertension in female mice.
Topics: Angiotensin II; Animals; Catalase; Cytochrome P-450 CYP1B1; Disease Models, Animal; Drinking; Estradiol; Female; Fibrosis; Genotype; Hypertension; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Natriuresis; Oxidative Stress; Phenotype; Renin-Angiotensin System; Sex Factors; Superoxide Dismutase; Superoxides; Tyrosine; Urination | 2015 |
Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Oxidative Stress; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptor 4; Up-Regulation; Vascular Remodeling | 2015 |
Epidermal growth factor receptor is critical for angiotensin II-mediated hypertrophy in cerebral arterioles.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; ErbB Receptors; Female; Gene Expression Regulation; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; RNA; Signal Transduction; Vascular Remodeling | 2015 |
Angiotensin Ⅱ Activates MCP-1 and Induces Cardiac Hypertrophy and Dysfunction via Toll-like Receptor 4.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Cardiomegaly; Chemokine CCL2; Hypertension; Irbesartan; Male; Mice; Mice, Inbred BALB C; Norepinephrine; Oxidative Stress; Tetrazoles; Toll-Like Receptor 4; Vasoconstrictor Agents | 2015 |
Nestin upregulation characterizes vascular remodeling secondary to hypertension in the rat.
Topics: Angiotensin II; Animals; Aorta; Carotid Arteries; Cells, Cultured; DNA Replication; Epidermal Growth Factor; Hypertension; Male; Muscle, Smooth, Vascular; Nestin; Rats; Rats, Sprague-Dawley; Up-Regulation; Vascular Remodeling | 2015 |
Beneficial effects of calcitriol on hypertension, glucose intolerance, impairment of endothelium-dependent vascular relaxation, and visceral adiposity in fructose-fed hypertensive rats.
Topics: Adiposity; Angiotensin II; Animals; Blood Pressure; Body Weight; Calcitriol; Dose-Response Relationship, Drug; Fructose; Glucose Intolerance; Glucose Tolerance Test; Hypertension; Male; Obesity, Abdominal; Rats; Rats, Inbred WKY; Vasodilation; Vitamins | 2015 |
Molecular markers of arterial hypertension in patients with normotony, pre-hypertension and hypertension.
Topics: Adult; Angiotensin II; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Prehypertension; S100 Calcium Binding Protein beta Subunit | 2015 |
Renal tubule angiotensin II type 1 receptor-associated protein promotes natriuresis and inhibits salt-sensitive blood pressure elevation.
Topics: Adaptor Proteins, Signal Transducing; Amiloride; Angiotensin II; Animals; Biomarkers; Blood Pressure; Cell Membrane; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Hypertension; Kidney Tubules, Distal; Mice, Inbred C57BL; Mice, Transgenic; Natriuresis; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2015 |
High salt intake damages the heart through activation of cardiac (pro) renin receptors even at an early stage of hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Echocardiography; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Heart Ventricles; HSP27 Heat-Shock Proteins; Hypertension; Lung; Male; Myocardium; Organ Size; p38 Mitogen-Activated Protein Kinases; Prorenin Receptor; Rats; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Signal Transduction; Sodium Chloride, Dietary; Transforming Growth Factor beta1 | 2015 |
ANG II modulation of cardiac growth and remodeling in immature fetal sheep.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Cardiomegaly; Cell Differentiation; Cell Enlargement; Cell Proliferation; Cell Size; Cyclin B1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Fetal Heart; Gestational Age; Hyperplasia; Hypertension; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Nitroprusside; Proliferating Cell Nuclear Antigen; Sheep; Signal Transduction; Time Factors; Vasodilator Agents | 2015 |
Pregnant rats treated with a high-fat/prooxidant Western diet with ANG II and TNF-α are resistant to elevations in blood pressure and renal oxidative stress.
Topics: Angiotensin II; Animals; Antioxidants; Aorta; Arterial Pressure; Birth Weight; Diet, High-Fat; Diet, Western; Disease Models, Animal; Female; Hypertension; Kidney Cortex; Litter Size; Nitric Oxide; Oxidative Stress; Pregnancy; Rats, Sprague-Dawley; Telemetry; Time Factors; Tumor Necrosis Factor-alpha | 2015 |
Effects of Taurine on Blood Index of Hypothalamic Pituitary Adrenal (HPA) Axis of Stress-Induced Hypertensive Rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Health Status Indicators; Hypertension; Hypothalamo-Hypophyseal System; Male; Norepinephrine; Peptidyl-Dipeptidase A; Pituitary-Adrenal System; Rats; Rats, Wistar; Stress, Psychological; Taurine | 2015 |
Vascular Type 1A Angiotensin II Receptors Control BP by Regulating Renal Blood Flow and Urinary Sodium Excretion.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Catecholamines; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Natriuresis; Phentolamine; Receptor, Angiotensin, Type 1; Renal Circulation; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents | 2015 |
Sympathoexcitation in ANG II-salt hypertension involves reduced SK channel function in the hypothalamic paraventricular nucleus.
Topics: Action Potentials; Angiotensin II; Animals; Arterial Pressure; Disease Models, Animal; Down-Regulation; Heart Rate; Hypertension; Kidney; Male; Paraventricular Hypothalamic Nucleus; Potassium Channel Blockers; Rats, Sprague-Dawley; Small-Conductance Calcium-Activated Potassium Channels; Sodium Chloride, Dietary; Splanchnic Nerves; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System; Time Factors | 2015 |
Hypertension exacerbates predisposition to neurodegeneration and memory impairment in the presence of a neuroinflammatory stimulus: Protection by angiotensin converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cerebral Cortex; Hippocampus; Hypertension; Inflammation Mediators; Lipopolysaccharides; Male; Maze Learning; Memory Disorders; Motor Activity; Nerve Degeneration; Oxidative Stress; Peptidyl-Dipeptidase A; Perindopril; Rats | 2015 |
Des-aspartate angiotensin I (DAA-I) reduces endothelial dysfunction in the aorta of the spontaneously hypertensive rat through inhibition of angiotensin II-induced oxidative stress.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Hypertension; Male; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2015 |
Angiotensin II activates the RhoA exchange factor Arhgef1 in humans.
Topics: Angiotensin II; Blotting, Western; Cells, Cultured; Humans; Hypertension; Leukocytes, Mononuclear; Muscle, Smooth, Vascular; Rho Guanine Nucleotide Exchange Factors; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Statistics, Nonparametric | 2015 |
6β-hydroxytestosterone, a cytochrome P450 1B1 metabolite of testosterone, contributes to angiotensin II-induced hypertension and its pathogenesis in male mice.
Topics: Angiotensin II; Animals; Cardiomegaly; Castration; Cytochrome P-450 CYP1B1; Disease Models, Animal; Gene Expression Regulation; Hydroxytestosterones; Hypertension; Male; Mice; Random Allocation; Reactive Oxygen Species; Reference Values | 2015 |
Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Calcium Channels; Cell Membrane; Chronic Disease; Enzyme Activation; Gene Deletion; HEK293 Cells; Humans; Hypertension; Lysophospholipids; Male; Mice, Inbred C57BL; Phosphotransferases (Alcohol Group Acceptor); Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine | 2015 |
Angiotensin type 1 receptor mediates chronic ethanol consumption-induced hypertension and vascular oxidative stress.
Topics: Alcohol Drinking; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Arteries; Blood Pressure; Ethanol; Hypertension; Losartan; Male; Oxidative Stress; Phosphorylation; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Vasoconstriction | 2015 |
Effect of lysyl oxidase inhibition on angiotensin II-induced arterial hypertension, remodeling, and stiffness.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Male; Mice; Mice, Inbred C57BL; Protein-Lysine 6-Oxidase; Pulse Wave Analysis; Vascular Remodeling; Vascular Stiffness; Vasoconstrictor Agents | 2015 |
Integrative network analysis reveals molecular mechanisms of blood pressure regulation.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Angiotensin II; Animals; Blood Pressure; Body Mass Index; Cohort Studies; Disease Models, Animal; Female; Gene Regulatory Networks; Genetic Loci; Genome-Wide Association Study; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Linear Models; Male; Membrane Proteins; Mice; Mice, Knockout; Middle Aged; Polymorphism, Single Nucleotide; Protein Interaction Domains and Motifs; RNA, Messenger; Sequence Analysis, RNA; Systems Biology; Transcriptome; Young Adult | 2015 |
Esculetin attenuates alterations in Ang II and acetylcholine mediated vascular reactivity associated with hyperinsulinemia and hyperglycemia.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Aorta; Blood Pressure; Diabetes Mellitus, Experimental; Hyperglycemia; Hyperinsulinism; Hypertension; Male; Peptidyl-Dipeptidase A; Rats, Wistar; Transforming Growth Factor beta; Umbelliferones | 2015 |
Novel role for retinol-binding protein 4 in the regulation of blood pressure.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Obesity; Phosphorylation; Retinol-Binding Proteins, Plasma; Vasodilation | 2015 |
Targeting γ-secretases protect against angiotensin II-induced cardiac hypertrophy.
Topics: Amyloid Precursor Protein Secretases; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Dibenzazepines; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Middle Aged; Muscle, Smooth, Vascular; Signal Transduction | 2015 |
Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Disease Models, Animal; Endoplasmic Reticulum Stress; Endothelium, Vascular; ErbB Receptors; Erlotinib Hydrochloride; Hypertension; Hypertrophy; Mice; Muscle, Smooth, Vascular; Phenylbutyrates; Quinazolines; Random Allocation; Role; Sensitivity and Specificity; Signal Transduction; Vascular Remodeling | 2015 |
Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo.
Topics: Aneurysm, Ruptured; Angiotensin II; Anilides; Animals; Cerebral Arteries; Endothelium, Vascular; Gene Expression Regulation; Genes, Dominant; Hypertension; Inflammation Mediators; Intracranial Aneurysm; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; Organ Specificity; Pancreatic Elastase; Pioglitazone; PPAR gamma; Subarachnoid Hemorrhage; Thiazolidinediones; Up-Regulation; Vasculitis | 2015 |
Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Angiotensin II; Animals; Blood Pressure; Cerebral Amyloid Angiopathy; Cerebrovascular Circulation; CHO Cells; Cricetulus; Disease Models, Animal; Hypertension; Male; Mice, Inbred C57BL; Mice, Transgenic | 2016 |
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Mice, Transgenic; Microvessels; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Time Factors; Vascular Remodeling | 2015 |
Skeletal muscle insulin resistance in salt-sensitive hypertension: role of angiotensin II activation of NFκB.
Topics: Angiotensin II; Animals; Hypertension; Insulin Resistance; Male; Muscle, Skeletal; NF-kappa B; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2015 |
β-Catenin-Dependent Signaling Pathway Contributes to Renal Fibrosis in Hypertensive Rats.
Topics: Angiotensin II; Animals; beta Catenin; Blood Pressure; Cyclin D1; Fibrosis; Humans; Hypertension; Kidney; Kidney Diseases; Lisinopril; Proto-Oncogene Proteins c-myc; Pyrvinium Compounds; Rats; Signal Transduction | 2015 |
Involvement of bone marrow cells and neuroinflammation in hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Bone Marrow Cells; Bone Marrow Transplantation; Chemokine CCL2; Female; Hypertension; Interleukin-1beta; Male; Microglia; Minocycline; Neurogenic Inflammation; Norepinephrine; Paraventricular Hypothalamic Nucleus; Radiation Chimera; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; T-Lymphocyte Subsets | 2015 |
Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress.
Topics: Angiotensin II; Animals; Aorta; Biflavonoids; Blood Pressure; Camellia sinensis; Capillary Resistance; Catechin; Cells, Cultured; Endoplasmic Reticulum Stress; Endothelial Cells; Endothelium, Vascular; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tea; Vasodilation | 2015 |
Rcan1-1L overexpression induces mitochondrial autophagy and improves cell survival in angiotensin II-exposed cardiomyocytes.
Topics: Angiotensin II; Autophagy; Autophagy-Related Protein 5; Cell Survival; Cells, Cultured; Cytochromes c; DNA-Binding Proteins; Humans; Hydrogen Peroxide; Hypertension; Intracellular Signaling Peptides and Proteins; Microtubule-Associated Proteins; Mitochondria, Heart; Mitophagy; Muscle Proteins; Myocytes, Cardiac; NFATC Transcription Factors; Oxidative Stress; Permeability | 2015 |
Endoplasmic reticulum and oxidant stress mediate nuclear factor-κB activation in the subfornical organ during angiotensin II hypertension.
Topics: Angiotensin II; Animals; Endoplasmic Reticulum; Gene Expression Regulation; Hypertension; Male; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Subfornical Organ | 2015 |
Activation of angiotensin-(1-7)/Mas axis in the brain lowers blood pressure and attenuates cardiac remodeling in hypertensive transgenic (mRen2)27 rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Heart; Heart Rate; Hypertension; Male; Myocardium; Peptide Fragments; Rats, Sprague-Dawley; Rats, Transgenic; Renin-Angiotensin System; RNA, Messenger | 2015 |
Elevated Endothelial Hypoxia-Inducible Factor-1α Contributes to Glomerular Injury and Promotes Hypertensive Chronic Kidney Disease.
Topics: Angiotensin II; Animals; Antigens, CD; Cadherins; Cells, Cultured; Disease Progression; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Feedback, Physiological; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Glomerulus; Mice; Mice, Transgenic; NF-kappa B; Organ Culture Techniques; Renal Insufficiency, Chronic; RNA, Small Interfering; Up-Regulation | 2015 |
Angiotensin II regulates brain (pro)renin receptor expression through activation of cAMP response element-binding protein.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Cell Line; CREB-Binding Protein; Desoxycorticosterone Acetate; Disease Models, Animal; Hypertension; Infusions, Intraventricular; Mice, Inbred C57BL; Paraventricular Hypothalamic Nucleus; Phosphorylation; Promoter Regions, Genetic; Prorenin Receptor; Proton-Translocating ATPases; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin-Angiotensin System; RNA Interference; RNA, Messenger; Signal Transduction; Sodium Chloride; Time Factors; Transcription Factor AP-1; Transfection; Up-Regulation | 2015 |
Role of the renin-angiotensin system, renal sympathetic nerve system, and oxidative stress in chronic foot shock-induced hypertension in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Corticosterone; Cyclic N-Oxides; Denervation; Electric Stimulation; Hypertension; Male; Oxidative Stress; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Spin Labels; Sympathetic Nervous System; Thiobarbituric Acid Reactive Substances | 2015 |
Src Family Kinases (SFK) Mediate Angiotensin II-Induced Myosin Light Chain Phosphorylation and Hypertension.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Humans; Hypertension; Male; Mice, Inbred C57BL; Models, Biological; Muscle Contraction; Myocytes, Smooth Muscle; Myosin Light Chains; Phosphorylation; src-Family Kinases | 2015 |
Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats.
Topics: Angiotensin II; Animals; Antigen Presentation; Aorta; Drug Evaluation, Preclinical; Genes, Synthetic; HeLa Cells; Hepatitis B Core Antigens; Humans; Hypertension; Immunization; Immunodominant Epitopes; Immunotherapy, Active; Isoantibodies; Kidney; Liver; Lymphocyte Activation; Male; Myocardium; Rats; Rats, Inbred SHR; Recombinant Fusion Proteins; T-Lymphocytes; Vaccines, DNA | 2015 |
Pretreatment with Relaxin Does Not Restore NO-Mediated Modulation of Calcium Signal in Coronary Endothelial Cells Isolated from Spontaneously Hypertensive Rats.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Coronary Vessels; Endothelial Cells; Humans; Hypertension; Male; Molecular Imaging; Nitric Oxide; Nitric Oxide Synthase Type III; Primary Cell Culture; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Relaxin; Thrombin | 2015 |
[The inversion of concepts about biological role of system rennin-angiotensin II- aldosterone and functions of arterial tension as a metabolism regulator].
Topics: Aldosterone; Angiotensin II; Arterial Pressure; Arteries; Chymosin; Essential Hypertension; Humans; Hypertension; Phylogeny; Renin-Angiotensin System; Vasodilation | 2015 |
Angiotensin II-induced hypertensive renal inflammation is mediated through HMGB1-TLR4 signaling in rat tubulo-epithelial cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Line; Epithelial Cells; HMGB1 Protein; Hypertension; Kidney Failure, Chronic; Kidney Tubules; Losartan; NF-kappa B; Rats; Signal Transduction; Toll-Like Receptor 4 | 2015 |
Cytosolic Phospholipase A2α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Endothelins; Fibrosis; Group IV Phospholipases A2; Hypertension; Kidney; Kidney Diseases; Male; Mice; Renal Circulation; Vascular Resistance | 2016 |
Microglia participate in neurogenic regulation of hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Diphtheria Toxin; Disease Models, Animal; Hypertension; Infusions, Intraventricular; Mice; Mice, Inbred C57BL; Microglia; NG-Nitroarginine Methyl Ester; Sympathetic Nervous System | 2015 |
Nanoparticle-mediated RNA interference of angiotensinogen decreases blood pressure and improves myocardial remodeling in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Gene Knockdown Techniques; Genetic Therapy; Hypertension; Male; Myocardium; Nanoparticles; Organ Size; Rats, Inbred SHR; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transfection; Ventricular Remodeling | 2015 |
M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Ly; Aorta; Arginase; Blood Pressure; Collagen; Elastin; Fibrosis; Hypertension; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Receptors, CCR2 | 2015 |
Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Echocardiography; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Norepinephrine; Oligonucleotide Array Sequence Analysis; Pressoreceptors; Vascular Remodeling | 2015 |
Arsenic causes aortic dysfunction and systemic hypertension in rats: Augmentation of angiotensin II signaling.
Topics: Angiotensin II; Animals; Aorta; Arsenic; Blood Pressure; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Male; NADPH Oxidases; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Signal Transduction; Superoxides; Up-Regulation | 2015 |
Activation of central PPAR-γ attenuates angiotensin II-induced hypertension.
Topics: Angiotensin II; Anilides; Animals; Blood Pressure; Brain; Disease Models, Animal; Hypertension; Infusions, Intraventricular; Infusions, Subcutaneous; Male; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathetic Nervous System; Thiazolidinediones; Ventricular Remodeling | 2015 |
Augmented Blood Pressure Variability in Hypertension Induced by Angiotensin II in Rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Rats, Inbred SHR; Rats, Wistar | 2016 |
Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice.
Topics: Angiotensin II; Animals; Apolipoprotein B-100; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression; Hypertension; Immunization; Kidney Diseases; Lymphocyte Depletion; Male; Mice; Mice, Knockout; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Peptides; Reactive Oxygen Species; T-Lymphocyte Subsets; Vaccines, Subunit | 2015 |
The angiotensin receptor blocker losartan reduces coronary arteriole remodeling in type 2 diabetic mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Blood Pressure; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypertension; Losartan; Male; Mice; Microvessels; Muscle, Smooth, Vascular; Pilot Projects; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2016 |
Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Kidney; Mice; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Sodium Chloride, Dietary | 2015 |
Conditional knockout of collecting duct bradykinin B2 receptors exacerbates angiotensin II-induced hypertension during high salt intake.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Knockout Techniques; Hypertension; Kidney Tubules, Collecting; Male; Mice; Receptor, Bradykinin B2; Sodium Chloride, Dietary | 2016 |
Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Hypertension; Immunity, Cellular; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Random Allocation; Sympathectomy | 2015 |
Pioglitazone Reduces Vascular Lipid Accumulation in Angiotensin II-Induced Hypertensive Rat.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Aorta; Hypertension; Immunohistochemistry; Lipid Metabolism; Lipids; Male; Pioglitazone; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Superoxides; Thiazolidinediones | 2015 |
Predicted effects of nitric oxide and superoxide on the vasoactivity of the afferent arteriole.
Topics: Algorithms; Angiotensin II; Animals; Arterioles; Calcium Channels, L-Type; Cyclic GMP; Cyclic N-Oxides; Enzyme Inhibitors; Free Radical Scavengers; Hypertension; Kidney; Male; Models, Statistical; Muscle, Smooth, Vascular; Myosins; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Renal Circulation; Spin Labels; Superoxides | 2015 |
[THE HUMORAL, NEUROHORMONAL VEGETATIVE AND HYDRAULIC REGULATION OF METABOLISM. THE DISTAL AND PROXIMAL SECTIONS OF ARTERIAL BLOODSTREAM. THE FATTY ACIDS AND METABOLIC ARTERIAL HYPERTENSION (A LECTURE)].
Topics: Angiotensin II; Animals; Arterial Pressure; Arterioles; Fatty Acids; Humans; Hypertension; Microcirculation; Sympathetic Nervous System | 2015 |
Profibrotic Role for Interleukin-4 in Cardiac Remodeling and Dysfunction.
Topics: Angiotensin II; Animals; Blood Pressure; Fibrosis; Heart; Hypertension; Interleukin-4; Macrophages; Mice; Mice, Knockout; Myocardium; Signal Transduction; Up-Regulation; Ventricular Remodeling | 2015 |
A revisit on the renin-angiotensin system in cardiovascular biology.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular System; Humans; Hypertension; Renin-Angiotensin System | 2016 |
Oleanolic acid alleviated pressure overload-induced cardiac remodeling.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Cardiomegaly; Diabetic Cardiomyopathies; Echocardiography; Fibrosis; Glucose; Hypertension; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oleanolic Acid; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Ventricular Remodeling | 2015 |
Antenatal Antioxidant Prevents Nicotine-Mediated Hypertensive Response in Rat Adult Offspring.
Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Body Weight; Enzyme Activation; Female; Humans; Hypertension; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotine; Nicotinic Agonists; Phorbol 12,13-Dibutyrate; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2015 |
Angiotensin and mineralocorticoid receptor antagonism attenuates cardiac oxidative stress in angiotensin II-infused rats.
Topics: Adrenal Glands; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Eplerenone; Heart Diseases; Hypertension; Lipid Peroxidation; Losartan; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Oxidative Stress; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction; Spironolactone; Time Factors; Tyrosine | 2015 |
Yiqi Huaju formula, a Chinese herbal medicine, reduces arterial pressure in salt‑sensitive hypertension by inhibiting renin‑angiotensin system activation.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression; Hypertension; Kidney; Male; Rats; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 2015 |
Immunosuppression-Independent Role of Regulatory T Cells against Hypertension-Driven Renal Dysfunctions.
Topics: Angiotensin II; Animals; Antigens, CD; Apoptosis; Apyrase; Cells, Cultured; Fibrosis; Hypertension; Immune Tolerance; Kidney; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Neutrophils; Proto-Oncogene Proteins c-vav; Renal Insufficiency; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 2015 |
Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension.
Topics: Aldosterone; Anesthesia; Angiotensin II; Animals; Blood Pressure; Electrolytes; Hypertension; Intestines; Kidney; Kidney Tubules; Male; Mice; Phenotype; Phosphorylation; Potassium; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers; Systole | 2015 |
Long-Term Regulation of the Local Renin-Angiotensin System in the Myocardium of Spontaneously Hypertensive Rats by Feeding Bioactive Peptides Derived from Spirulina platensis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Male; Myocardium; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spirulina | 2015 |
Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Aortic Aneurysm, Abdominal; Calcium Channels, L-Type; Humans; Hypertension; Mice; Mice, Transgenic; NADPH Oxidases; Nifedipine; Nitric Oxide Synthase Type III; Oxidative Stress; Phenylketonurias | 2015 |
α-Lipoic acid reduces neurogenic hypertension by blunting oxidative stress-mediated increase in ADAM17.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Baroreflex; Cell Line, Tumor; Hypertension; Hypothalamus; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Neurons; Oxidative Stress; Peptidyl-Dipeptidase A; Thioctic Acid | 2015 |
AT2R autoantibodies block angiotensin II and AT1R autoantibody-induced vasoconstriction.
Topics: Angiotensin II; Animals; Antibodies, Blocking; Arterioles; Autoantibodies; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Male; Rabbits; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstriction | 2015 |
[IMPACT OF LONG-TERM ADAPTATION TO COLD ON THE STATE OF CARDIOVASCULAR SYSTEM].
Topics: Acclimatization; Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Arctic Regions; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; Cold Temperature; Coronary Disease; Humans; Hypertension; Myocytes, Cardiac; Rats; Receptors, Adrenergic, alpha | 2015 |
Changes in protein and gene expression of angiotensin II receptors (AT1 and AT2) in aorta of diabetic and hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Diabetes Mellitus, Experimental; Gene Expression Profiling; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger | 2016 |
Maternal hyperthyroidism increases the susceptibility of rat adult offspring to cardiovascular disorders.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Disease Models, Animal; Disease Susceptibility; Female; Hypertension; Hyperthyroidism; Male; Myocardial Reperfusion Injury; Plethysmography; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Thyroxine | 2015 |
Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in Hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antigens, Ly; Blood Pressure; CD11b Antigen; Cells, Cultured; Disease Models, Animal; Hydrogen Peroxide; Hypertension; Immune Tolerance; Inflammation Mediators; Lymphocyte Activation; Male; Membrane Glycoproteins; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; NADPH Oxidase 2; NADPH Oxidases; Nephritis; NG-Nitroarginine Methyl Ester; Signal Transduction; Sodium, Dietary; T-Lymphocytes; Time Factors | 2015 |
Sex differences in NMDA GluN1 plasticity in rostral ventrolateral medulla neurons containing corticotropin-releasing factor type 1 receptor following slow-pressor angiotensin II hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Gene Expression Regulation; Green Fluorescent Proteins; Hypertension; Male; Medulla Oblongata; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Receptors, Corticotropin-Releasing Hormone; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sex Characteristics; Stilbamidines; Subcellular Fractions; Tyrosine 3-Monooxygenase | 2015 |
The Neuroimmune Axis in the Kidney: Role in Hypertension.
Topics: Angiotensin II; Animals; Hypertension; Immunity, Cellular; Kidney; Sympathectomy | 2015 |
Pentoxifylline Ameliorates Cardiac Fibrosis, Pathological Hypertrophy, and Cardiac Dysfunction in Angiotensin II-induced Hypertensive Rats.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibrosis; Hypertension; Inflammation Mediators; Male; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley | 2016 |
Serum apelin is associated with left ventricular hypertrophy in untreated hypertension patients.
Topics: Adult; Angiotensin II; Animals; Apelin; Apelin Receptors; Blood Pressure; C-Reactive Protein; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Intercellular Signaling Peptides and Proteins; Ligands; Male; Middle Aged; Myocytes, Cardiac; Natriuretic Peptide, Brain; Prevalence; Rats; Receptors, G-Protein-Coupled; ROC Curve; Transfection | 2015 |
Obligatory Role for B Cells in the Development of Angiotensin II-Dependent Hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antibodies, Anti-Idiotypic; Antigens, CD20; B-Cell Activation Factor Receptor; B-Lymphocytes; Cell Proliferation; Disease Models, Animal; Hypertension; Immunoglobulin G; Mice; Mice, Knockout; Spleen; Transforming Growth Factor beta; Vascular Stiffness | 2015 |
NLRP3 Deficiency Improves Angiotensin II-Induced Hypertension But Not Fetal Growth Restriction During Pregnancy.
Topics: Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Disease Models, Animal; Female; Fetal Growth Retardation; Hypertension; Hypertension, Pregnancy-Induced; Inflammasomes; Interleukin-6; Kidney; Mice; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Placenta; Pregnancy | 2015 |
NPY1-36 and PYY1-36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4.
Topics: Angiotensin II; Animals; Cell Proliferation; Collagen; Dipeptidyl-Peptidase IV Inhibitors; Estrenes; Fibroblasts; GTP-Binding Proteins; Hypertension; Indoles; Maleimides; Myocardium; Neuropeptide Y; Peptide Fragments; Peptide YY; Pertussis Toxin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors for Activated C Kinase; Signal Transduction; Sitagliptin Phosphate; Type C Phospholipases | 2015 |
Dimethylarginine dimethylaminohydrolase-1 mediates inhibitory effect of interleukin-10 on angiotensin II-induced hypertensive effects in vascular smooth muscle cells of spontaneously hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Animals; Arachidonate 12-Lipoxygenase; Blotting, Western; Cell Proliferation; Cells, Cultured; Endothelin-1; Gene Expression; Hypertension; Interleukin-10; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Vasoconstrictor Agents | 2016 |
Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Cells, Cultured; Cyclic N-Oxides; Disease Models, Animal; Elastic Tissue; Elastin; Free Radical Scavengers; Hypertension; Matrix Metalloproteinases; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Sirtuin 1; Spin Labels; Time Factors | 2015 |
Tumor Necrosis Factor - Alpha Is Essential for Angiotensin II-Induced Ventricular Remodeling: Role for Oxidative Stress.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Collagen Type I; Collagen Type III; Connective Tissue Growth Factor; Fibrosis; Heart; Hypertension; Male; MAP Kinase Signaling System; Mice; Myocardium; NADPH Oxidases; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2015 |
Prolonged Subcutaneous Administration of Oxytocin Accelerates Angiotensin II-Induced Hypertension and Renal Damage in Male Rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Calcineurin; Cardiomegaly; Hypertension; Injections, Subcutaneous; Kidney; Male; Oxytocin; Rats; Rats, Sprague-Dawley; Renin | 2015 |
Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis.
Topics: Aging; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Chemokine CCL2; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Glucagon-Like Peptide-1 Receptor; Heart; Heart Diseases; Hypertension; I-kappa B Proteins; Immunohistochemistry; Incretins; Inflammation; Interleukin-10; Liraglutide; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocardium; NF-kappa B p50 Subunit; Obesity; Oxidative Stress; Real-Time Polymerase Chain Reaction; Vasoconstrictor Agents; Vimentin | 2016 |
Effect of angiotensin II-induced arterial hypertension on the voltage-dependent contractions of mouse arteries.
Topics: Action Potentials; Angiotensin II; Animals; Arteries; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Cromakalim; Diltiazem; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Potassium; Vasodilation | 2016 |
Depressor effect of chymase inhibitor in mice with high salt-induced moderate hypertension.
Topics: Albuminuria; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chymases; Disease Models, Animal; Diuretics; Heart Rate; Hypertension; Male; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Serine Proteinase Inhibitors; Sodium Chloride, Dietary; Time Factors | 2015 |
Consequences of postnatal vascular smooth muscle EGFR deletion on acute angiotensin II action.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Gene Deletion; Humans; Hypertension; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Plasminogen Activator Inhibitor 1; Signal Transduction; Time Factors; Vascular Remodeling; Vasoconstrictor Agents | 2016 |
Differential activation of renal sympathetic burst amplitude and frequency during hypoxia, stress and baroreflexes with chronic angiotensin treatment.
Topics: Action Potentials; Angiotensin II; Animals; Baroreflex; Blood Pressure; Carbon Dioxide; Chemoreceptor Cells; Disease Models, Animal; Heart Rate; Hypertension; Hypoxia; Kidney; Male; Oxygen; Pressoreceptors; Rabbits; Stress, Physiological; Sympathetic Nervous System; Time Factors | 2015 |
Cofilin1 is involved in hypertension-induced renal damage via the regulation of NF-κB in renal tubular epithelial cells.
Topics: Angiotensin II; Animals; Antioxidants; Chemokine CCL2; Cofilin 1; Creatinine; Cytoskeleton; Epithelial Cells; Gene Expression Regulation; Grape Seed Extract; Humans; Hypertension; Inflammation; Interleukin-1beta; Kidney Tubules; Male; NF-kappa B p50 Subunit; Nitrogen; Proanthocyanidins; Rats; Rats, Inbred SHR; Renal Insufficiency; RNA, Small Interfering; Urea | 2015 |
Amlodipine suppresses Ang-II-induced endothelium dysfunction by diminishing ROCK1 expression.
Topics: Amlodipine; Angiotensin II; Apoptosis; bcl-2-Associated X Protein; Calcium Channel Blockers; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphoproteins; Proto-Oncogene Proteins c-bcl-2; rho-Associated Kinases; Vasoconstrictor Agents | 2016 |
Characteristics of renal sympathetic nerve single units in rabbits with angiotensin-induced hypertension.
Topics: Action Potentials; Angiotensin II; Animals; Arrhythmias, Cardiac; Baroreflex; Dose-Response Relationship, Drug; Electrocardiography; Heart; Hemodynamics; Hypertension; Kidney; Male; Rabbits; Sympathetic Nervous System; Vasoconstrictor Agents | 2016 |
Angiotensin II status and sympathetic activation among hypertensive patients in Uganda: a cross-sectional study.
Topics: Adolescent; Adult; Angiotensin II; Cross-Sectional Studies; Female; Humans; Hypertension; Male; Metanephrine; Middle Aged; Multivariate Analysis; Normetanephrine; Renin; Sympathetic Nervous System; Uganda; Young Adult | 2015 |
ANG II-induced hypertension in the VCD mouse model of menopause is prevented by estrogen replacement during perimenopause.
Topics: Angiotensin II; Animals; Aquaporin 2; Arterial Pressure; Cell Proliferation; Cyclohexenes; Disease Models, Animal; Drug Administration Schedule; Estradiol; Estrogen Replacement Therapy; Female; Hypertension; Injections, Intraperitoneal; Kidney Cortex; Menopause; Mice, Inbred C57BL; Perimenopause; Risk Factors; Time Factors; Vinyl Compounds | 2015 |
Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis.
Topics: Angiotensin II; Animals; Disease Progression; Hypertension; Mice; Mice, Transgenic; Pulmonary Fibrosis; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2015 |
Hypertension Impairs Cerebral Blood Flow in a Mouse Model for Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Angiotensin II; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Essential Hypertension; Hippocampus; Humans; Hypertension; Male; Mice, Inbred C57BL; Mice, Transgenic; Presenilin-1; Thalamus | 2015 |
Renal medullary (pro)renin receptor contributes to angiotensin II-induced hypertension in rats via activation of the local renin-angiotensin system.
Topics: Angiotensin II; Animals; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Receptors, Cell Surface; Renin; Renin-Angiotensin System | 2015 |
Angiotensin II-Induced Hypertension Is Attenuated by Reduction of Sympathetic Output in NO-Sensitive Guanylyl Cyclase 1 Knockout Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclic GMP; Guanylate Cyclase; Heart Rate; Hypertension; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Norepinephrine; Phosphoric Diester Hydrolases; Receptors, Cell Surface; Sympathetic Nervous System; Vasoconstrictor Agents; Vasodilation | 2016 |
Central Renin-Angiotensin System Activation and Inflammation Induced by High-Fat Diet Sensitize Angiotensin II-Elicited Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Hypertension; Inflammation; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2016 |
Impaired response of regulator of Gαq signaling-2 mRNA to angiotensin II and hypertensive renal injury in Dahl salt-sensitive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred Dahl; RGS Proteins; Sodium, Dietary | 2016 |
Deficiency of T-regulatory cells exaggerates angiotensin II-induced microvascular injury by enhancing immune responses.
Topics: Adipose Tissue; Adoptive Transfer; Angiotensin II; Animals; Blood Pressure; CD4 Lymphocyte Count; Chemokine CCL2; Endothelium; Forkhead Transcription Factors; Homeodomain Proteins; Hypertension; Immunity, Innate; Kidney Cortex; Macrophages; Male; Mesenteric Arteries; Mice; Mice, Knockout; Microvessels; Monocytes; Oxidative Stress; T-Lymphocytes, Regulatory; Vascular Remodeling; Vascular Stiffness | 2016 |
Endoplasmic reticulum stress in the brain subfornical organ contributes to sex differences in angiotensin-dependent hypertension in rats.
Topics: Angiotensin II; Animals; Blotting, Western; Endoplasmic Reticulum Stress; Female; Hypertension; Immunohistochemistry; Male; Ovariectomy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Sex Characteristics; Subfornical Organ; Vasoconstrictor Agents | 2016 |
Alterations in the subcellular distribution of NADPH oxidase p47(phox) in hypothalamic paraventricular neurons following slow-pressor angiotensin II hypertension in female mice with accelerated ovarian failure.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; NADPH Oxidases; Neurons; Paraventricular Hypothalamic Nucleus; Postmenopause; Sex Characteristics | 2016 |
Experimental hypertension increases spontaneous intracerebral hemorrhages in a mouse model of cerebral amyloidosis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin II; Animals; Blood Pressure; Brain; Cerebral Amyloid Angiopathy; Female; Humans; Hypertension; Intracranial Hemorrhage, Hypertensive; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Risk Factors; Stroke | 2016 |
Angiotensinogen Exerts Effects Independent of Angiotensin II.
Topics: Amides; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Blood Pressure; Conserved Sequence; Dependovirus; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Fumarates; Genetic Vectors; Genotype; Hepatocytes; Hypertension; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Oligonucleotides, Antisense; Phenotype; Protein Binding; Protein Interaction Domains and Motifs; Receptors, LDL; Renin; Signal Transduction; Time Factors; Transduction, Genetic; Weight Gain | 2016 |
Interleukin-10 limits increased blood pressure and vascular RhoA/Rho-kinase signaling in angiotensin II-infused mice.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Inflammation; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; rho-Associated Kinases; Signal Transduction | 2016 |
Different regulation of miR-29a-3p in glomeruli and tubules in an experimental model of angiotensin II-dependent hypertension: potential role in renal fibrosis.
Topics: Angiotensin II; Animals; Base Sequence; Blood Pressure; Down-Regulation; Fibrosis; Glomerular Filtration Rate; Hypertension; Kidney Glomerulus; Kidney Tubules; Male; Matrix Metalloproteinase 2; MicroRNAs; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2016 |
Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron.
Topics: Angiotensin II; Animals; Biological Availability; Blood Pressure; Hypertension; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Nephrons; Nitric Oxide; Receptors, Interleukin-1; Renal Reabsorption; Renin-Angiotensin System; Signal Transduction; Sodium Chloride, Dietary; Solute Carrier Family 12, Member 1 | 2016 |
Transient Exposure of Enalapril Normalizes Prenatal Programming of Hypertension and Urinary Angiotensinogen Excretion.
Topics: Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Enalapril; Female; Hypertension; Kidney; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2015 |
Possible role for nephron-derived angiotensinogen in angiotensin-II dependent hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nephrons; Sodium, Dietary | 2016 |
Hypercholesterolemia blunts the oxidative stress elicited by hypertension in venules through angiotensin II type-2 receptors.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apolipoproteins E; Cell Adhesion; Chemotaxis, Leukocyte; Cholesterol, Dietary; Disease Models, Animal; Hypercholesterolemia; Hypertension; Leukocytes; Male; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Receptor, Angiotensin, Type 2; Signal Transduction; Venules | 2016 |
Hypertension: A Disease That Strikes Around the Clock.
Topics: Angiotensin II; Animals; Blood Pressure; Circadian Rhythm; Diet, Sodium-Restricted; Hypertension; Male; Sodium Chloride, Dietary | 2016 |
Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Circadian Rhythm; Diet, Sodium-Restricted; Disease Models, Animal; Hypertension; Male; Mice; Mice, Knockout; Sodium Chloride, Dietary | 2016 |
Angiotensin II Regulation of Proliferation, Differentiation, and Engraftment of Hematopoietic Stem Cells.
Topics: Angiotensin II; Animals; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Hypertension; Male; Mice; Mice, Inbred BALB C; Video Recording | 2016 |
Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II-induced hypertension.
Topics: Aging; Angiotensin II; Animals; HEK293 Cells; Humans; Hypertension; Mice; Mice, Knockout; Protein Multimerization; Receptor, Angiotensin, Type 1; Receptors, Purinergic P2 | 2016 |
Methylmercury affects cerebrovascular reactivity to angiotensin II and acetylcholine via Rho-kinase and nitric oxide pathways in mice.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Arterial Pressure; Blood Pressure; Hypertension; Male; Methylmercury Compounds; Mice; Mice, Inbred ICR; Nitric Oxide; rho-Associated Kinases; Vasoconstriction; Vasodilation | 2016 |
Mechanism of IFN-γ in regulating OPN/Th17 pathway during vascular collagen remodeling of hypertension induced by ANG II.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Differentiation; Cells, Cultured; Collagen Type I; Collagen Type III; Disease Models, Animal; Hypertension; Inflammation Mediators; Interferon-gamma; Interleukin-10; Interleukin-23; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 1; Nuclear Receptor Subfamily 1, Group F, Member 3; Osteopontin; Procollagen; Spleen; Th17 Cells; Transforming Growth Factor beta; Vascular Remodeling | 2015 |
Roles of Caveolin-1 in Angiotensin II-Induced Hypertrophy and Inward Remodeling of Cerebral Pial Arterioles.
Topics: Angiotensin II; Animals; Arterioles; Caveolin 1; Disease Models, Animal; Gene Expression Regulation; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; RNA; Vascular Remodeling | 2016 |
Role of α1D -adrenoceptors in vascular wall hypertrophy during angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 2015 |
Augmentation of angiotensinogen expression in the proximal tubule by intracellular angiotensin II via AT1a/MAPK/NF-кB signaling pathways.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension; Kidney Tubules, Proximal; Male; MAP Kinase Signaling System; NF-kappa B; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Sodium | 2016 |
Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension.
Topics: Angiotensin II; Animals; Chemokine CCL5; Female; Gene Expression Regulation; Humans; Hypertension; Interferon-gamma; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Signal Transduction; T-Lymphocytes; Vasculitis | 2016 |
GPER activation ameliorates aortic remodeling induced by salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Animals, Congenic; Aorta; Blood Pressure; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Genotype; Glycosaminoglycans; Hypertension; Lipid Peroxidation; Oxidative Stress; Phenylephrine; Quinolines; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin; Sodium Chloride, Dietary; Time Factors; Vascular Remodeling | 2016 |
"Angiotensin II memory" contributes to the development of hypertension and vascular injury via activation of NADPH oxidase.
Topics: Angiotensin II; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Hypertension; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Organ Culture Techniques; Vascular System Injuries | 2016 |
Angiotensin II-Induced Hypertension Is Attenuated by Overexpressing Copper/Zinc Superoxide Dismutase in the Brain Organum Vasculosum of the Lamina Terminalis.
Topics: Adenoviridae; Angiotensin II; Animals; Blood Pressure; Hemodynamics; Humans; Hypertension; Hypothalamus; Male; Microscopy, Confocal; Microscopy, Fluorescence; Organum Vasculosum; Oxygen; Rats; Signal Transduction; Subfornical Organ; Superoxide Dismutase-1 | 2016 |
Exercise Training Improves the Altered Renin-Angiotensin System in the Rostral Ventrolateral Medulla of Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Chromatography, High Pressure Liquid; Citrate (si)-Synthase; Hypertension; Male; Medulla Oblongata; Oxidative Stress; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Renin-Angiotensin System; Signal Transduction | 2016 |
LncDisease: a sequence based bioinformatics tool for predicting lncRNA-disease associations.
Topics: Angiotensin II; Breast Neoplasms; Cell Line, Tumor; Computational Biology; Female; Humans; Hypertension; MCF-7 Cells; MicroRNAs; Muscle, Smooth, Vascular; RNA, Long Noncoding; Software | 2016 |
Angiotensin II-mediated hypertension impairs nitric oxide-induced NKCC2 inhibition in thick ascending limbs.
Topics: Angiotensin II; Animals; Cyclic CMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Endothelin-1; Hypertension; Loop of Henle; Male; Nitric Oxide; Nitric Oxide Donors; Phosphodiesterase 5 Inhibitors; Rats; Rats, Sprague-Dawley; Solute Carrier Family 12, Member 1; Vardenafil Dihydrochloride | 2016 |
Comparison of sympathetic nerve activity normalization procedures in conscious rabbits.
Topics: Action Potentials; Angiotensin II; Animals; Arterial Pressure; Baroreflex; Blood Pressure Determination; Calibration; Consciousness; Constriction; Diet, High-Fat; Disease Models, Animal; Electrodiagnosis; Heart Rate; Hypertension; Kidney; Male; Models, Animal; Muscle, Skeletal; Nasopharynx; Rabbits; Renal Artery; Reproducibility of Results; Signal Processing, Computer-Assisted; Sympathetic Nervous System; Telemetry; Time Factors | 2016 |
Renal intramedullary infusion of tempol normalizes the blood pressure response to intrarenal blockade of heme oxygenase-1 in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Heme Oxygenase-1; Humans; Hypertension; Infusions, Parenteral; Kidney Medulla; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Spin Labels; Superoxides | 2016 |
Transient Receptor Potential Melastatin 7 Cation Channel Kinase: New Player in Angiotensin II-Induced Hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Random Allocation; Reactive Oxygen Species; Risk Assessment; TRPM Cation Channels; Up-Regulation; Ventricular Dysfunction, Left | 2016 |
6β-Hydroxytestosterone, a Cytochrome P450 1B1-Testosterone-Metabolite, Mediates Angiotensin II-Induced Renal Dysfunction in Male Mice.
Topics: Analysis of Variance; Angiotensin II; Animals; Biopsy, Needle; Castration; Cytochrome P-450 CYP1B1; Disease Models, Animal; Hydroxytestosterones; Hypertension; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Male; Mice; Oxidative Stress; Random Allocation; Reactive Oxygen Species; Reference Values; Risk Factors; RNA, Messenger | 2016 |
BDNF acting in the hypothalamus induces acute pressor responses under permissive control of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain-Derived Neurotrophic Factor; Cardiovascular System; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Vasoconstrictor Agents | 2016 |
TMEM16A contributes to angiotensin II-induced cerebral vasoconstriction via the RhoA/ROCK signaling pathway.
Topics: Amides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anoctamin-1; Basilar Artery; Cells, Cultured; Chloride Channels; Disease Models, Animal; Evoked Potentials; Hypertension; Male; Muscle, Smooth, Vascular; Protein Phosphatase 1; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstriction | 2016 |
Thrombospondin-4 knockout in hypertension protects small-artery endothelial function but induces aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Cardiomegaly; Collagen; Dilatation, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Genetic Predisposition to Disease; Hypertension; Mesenteric Arteries; Mice, Knockout; Microscopy, Electron; Phenotype; Thrombospondins; Vascular Resistance; Vasodilation; Vasodilator Agents | 2016 |
Excessive Adventitial Remodeling Leads to Early Aortic Maladaptation in Angiotensin-Induced Hypertension.
Topics: Adventitia; Analysis of Variance; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mice; Mice, Inbred C57BL; Random Allocation; Stress, Physiological; Vascular Remodeling; Vascular Stiffness | 2016 |
Leptin Mediates High-Fat Diet Sensitization of Angiotensin II-Elicited Hypertension by Upregulating the Brain Renin-Angiotensin System and Inflammation.
Topics: Angiotensin II; Animals; Blood Pressure Determination; Cytokines; Diet, High-Fat; Disease Models, Animal; Hypertension; Inflammation; Leptin; Male; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Renin-Angiotensin System; RNA, Messenger; Up-Regulation | 2016 |
Renal hemodynamics and renin-angiotensin system activity in humans with multifocal renal artery fibromuscular dysplasia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Case-Control Studies; Enzyme Inhibitors; Essential Hypertension; Female; Fibromuscular Dysplasia; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renovascular; Male; Microvessels; Middle Aged; Nitric Oxide Synthase; Peptide Fragments; Renal Artery; Renal Circulation; Renin; Renin-Angiotensin System; Sex Factors | 2016 |
The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Hypertension; Kidney; Mice; Mice, Knockout; Myocardium; Receptor, Anaphylatoxin C5a | 2016 |
Mitochondrial Cyclophilin D in Vascular Oxidative Stress and Hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Biomarkers; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclophilins; Disease Models, Animal; Endothelium, Vascular; Hypertension; Lactones; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Random Allocation; Spiro Compounds; Superoxides; Vasodilation | 2016 |
Redistribution of NMDA Receptors in Estrogen-Receptor-β-Containing Paraventricular Hypothalamic Neurons following Slow-Pressor Angiotensin II Hypertension in Female Mice with Accelerated Ovarian Failure.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Green Fluorescent Proteins; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; Nerve Tissue Proteins; Neurons; Ovarian Diseases; Paraventricular Hypothalamic Nucleus; Reactive Oxygen Species; Receptors, Estrogen; Receptors, N-Methyl-D-Aspartate; Vinyl Compounds | 2017 |
Context-dependent effects of SOCS3 in angiotensin II-induced vascular dysfunction and hypertension in mice: mechanisms and role of bone marrow-derived cells.
Topics: Angiotensin II; Animals; Aorta; Basilar Artery; Bone Marrow Cells; Bone Marrow Transplantation; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Genotype; Hypertension; Interleukin-6; Male; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Organ Culture Techniques; Phenotype; Signal Transduction; STAT3 Transcription Factor; Superoxides; Suppressor of Cytokine Signaling 3 Protein; Vasodilation; Vasodilator Agents | 2016 |
Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Aortic Coarctation; Captopril; Catalase; Clofibrate; Drug Synergism; Heart Ventricles; Hypertension; Lipid Peroxidation; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; PPAR alpha; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Superoxide Dismutase; Vasodilation | 2016 |
P‑selectin increases angiotensin II‑induced cardiac inflammation and fibrosis via platelet activation.
Topics: Angiotensin II; Animals; Blood Platelets; Disease Models, Animal; Endothelial Cells; Fibrosis; Gene Expression; Hypertension; Immunohistochemistry; Male; Mice; Mice, Knockout; Myocarditis; Myocardium; P-Selectin; Platelet Activation | 2016 |
Collecting duct (pro)renin receptor targets ENaC to mediate angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Epithelial Sodium Channels; Hypertension; Kidney Tubules, Collecting; Mice; Mice, Knockout; Peptide Fragments; Prorenin Receptor; Receptors, Cell Surface; Renin | 2017 |
Impact of Angiotensin Type 1A Receptors in Principal Cells of the Collecting Duct on Blood Pressure and Hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Hypertension; Kidney Tubules, Collecting; Mice; Random Allocation; Receptor, Angiotensin, Type 1; Reference Values; Renin-Angiotensin System | 2016 |
Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension.
Topics: Acute Kidney Injury; Analysis of Variance; Angiotensin II; Animals; Blood Pressure Determination; Cells, Cultured; Disease Models, Animal; Hypertension; Immunoblotting; Interleukin-17; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Random Allocation; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Sodium Chloride Symporters; Solute Carrier Family 12, Member 3 | 2016 |
Letter by Campbell Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects".
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Renin | 2016 |
Response to Letter Regarding Article, "Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects".
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diabetes Mellitus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Renin | 2016 |
Curcumin Exerts its Anti-hypertensive Effect by Down-regulating the AT1 Receptor in Vascular Smooth Muscle Cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Line; Curcumin; Down-Regulation; Gene Expression Regulation; Hypertension; Mesenteric Arteries; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Protein Binding; Rats; Receptor, Angiotensin, Type 1; Sp1 Transcription Factor; Vasoconstriction | 2016 |
Dietary Calanus oil antagonizes angiotensin II-induced hypertension and tissue wasting in diet-induced obese mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Body Weight; Copepoda; Diet, High-Fat; Dietary Fats, Unsaturated; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Organ Size; Random Allocation; Treatment Outcome | 2016 |
Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II-mediated hypertension.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension; Mice; Mice, Inbred C57BL; NADPH Oxidases; Nitrates; Nitric Oxide; Oxidative Stress; Propane; Rats; Rats, Wistar | 2016 |
Mineralocorticoid and angiotensin II type 1 receptors in the subfornical organ mediate angiotensin II - induced hypothalamic reactive oxygen species and hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dependovirus; Gene Knockdown Techniques; Genetic Vectors; Heart Rate; Hypertension; Hypothalamus; Male; Medulla Oblongata; Random Allocation; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; RNA, Messenger; RNA, Small Interfering; Subfornical Organ | 2016 |
Estrogen therapy may counterbalance eutrophic remodeling of coronary arteries and increase bradykinin relaxation in a rat model of menopausal hypertension.
Topics: Angiotensin II; Animals; Bradykinin; Coronary Vessels; Disease Models, Animal; Estrogen Replacement Therapy; Estrogens; Female; Hypertension; Menopause; Ovariectomy; Rats; Rats, Sprague-Dawley; Vascular Remodeling; Vasoconstrictor Agents; Vasodilator Agents | 2016 |
Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Mesenteric Arteries; Mice, Inbred C57BL; Norepinephrine; PPAR-beta; RGS Proteins; Sulfones; Thiazoles; Thiophenes; Vascular Resistance; Vasoconstriction | 2016 |
The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas axes in pressure overload-induced cardiac remodeling in male mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Echocardiography; Hemodynamics; Hypertension; Male; Mice; Mice, Knockout; Myocardium; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction; Ventricular Remodeling | 2016 |
Acute eprosartan-induced intrarenal vasodilation in hypertensive humans is not influenced by dietary sodium intake or angiotensin II co-infusion.
Topics: Acrylates; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Artery; Renal Circulation; Renin-Angiotensin System; Sodium; Sodium, Dietary; Thiophenes; Vasodilation | 2016 |
Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans.
Topics: Adult; Analysis of Variance; Angiotensin II; Animals; Antibodies, Monoclonal, Humanized; Cells, Cultured; Chi-Square Distribution; Disease Models, Animal; Humans; Hypertension; Kidney; Lymphocyte Activation; Mice; Middle Aged; Random Allocation; Reference Values; Sampling Studies; Statistics, Nonparametric; T-Lymphocytes, Regulatory | 2016 |
Long-Term Supplementation of Microencapsulated ursodeoxycholic Acid Prevents Hypertension in a Mouse Model of Insulin Resistance.
Topics: Angiotensin II; Animals; Capsules; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Hypertension; Insulin Resistance; Male; Mice; Time Factors; Ursodeoxycholic Acid | 2017 |
Periostin expression induced by oxidative stress contributes to myocardial fibrosis in a rat model of high salt-induced hypertension.
Topics: Angiotensin II; Animals; Biomarkers; Blood Pressure; Cardiomyopathies; Cell Adhesion Molecules; Disease Models, Animal; Fibrosis; Gene Expression; Gene Expression Regulation; Hypertension; Male; Oxidative Stress; Rats; Reactive Oxygen Species; Sodium Chloride, Dietary | 2016 |
Possible role for brain prostanoid pathways in the development of angiotensin II-salt hypertension in rats.
Topics: Angiotensin II; Animals; Brain; Disease Models, Animal; Hypertension; Male; Neurovascular Coupling; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride, Dietary | 2016 |
Whey peptide Isoleucine-Tryptophan inhibits expression and activity of matrix metalloproteinase-2 in rat aorta.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dipeptides; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Losartan; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Rats; Renin-Angiotensin System; Vascular Stiffness; Whey Proteins | 2016 |
Vascular Smooth Muscle-Specific EP4 Receptor Deletion in Mice Exacerbates Angiotensin II-Induced Renal Injury.
Topics: Angiotensin II; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Kidney Diseases; Mesenteric Arteries; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Oxidative Stress; Receptors, Prostaglandin E, EP4 Subtype; Renal Circulation | 2016 |
p38 MAPK Inhibition Improves Synaptic Plasticity and Memory in Angiotensin II-dependent Hypertensive Mice.
Topics: Angiotensin II; Animals; Dendritic Spines; Disease Models, Animal; Hippocampus; Humans; Hypertension; Imidazoles; Long-Term Potentiation; Mice; Neuronal Plasticity; p38 Mitogen-Activated Protein Kinases; Pyramidal Cells; Signal Transduction; Thiazoles | 2016 |
AT2 Receptor Activation Prevents Sodium Retention and Reduces Blood Pressure in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Female; Hypertension; Natriuresis; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sodium; Sulfonamides; Thiophenes | 2016 |
α7 Nicotinic Acetylcholine Receptor Relieves Angiotensin II-Induced Senescence in Vascular Smooth Muscle Cells by Raising Nicotinamide Adenine Dinucleotide-Dependent SIRT1 Activity.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Genotype; Histone Deacetylase Inhibitors; Humans; Hypertension; Mice, Knockout; Muscle, Smooth, Vascular; NAD; Nicotinic Agonists; Oxidative Stress; Phenotype; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Sirtuin 1; Time Factors; Transfection; Up-Regulation | 2016 |
Genipin ameliorates hypertension-induced renal damage via the angiotensin II-TLR/MyD88/MAPK pathway.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cell Proliferation; Cytokines; Humans; Hypertension; Iridoids; Kidney; Male; MAP Kinase Signaling System; Mesangial Cells; Myeloid Differentiation Factor 88; Rats, Inbred SHR; Reactive Oxygen Species; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2016 |
Protective effects of MCR-1329, a dual α1 and angII receptor antagonist, in mineralocorticoid-induced hypertension.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Chromones; Desoxycorticosterone Acetate; Endothelium, Vascular; Hypertension; Losartan; Male; Mineralocorticoids; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Prazosin; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Angiotensin; Signal Transduction; Vasoconstriction | 2016 |
A dipeptidyl peptidase-4 inhibitor ameliorates hypertensive cardiac remodeling via angiotensin-II/sodium-proton pump exchanger-1 axis.
Topics: Angiotensin II; Animals; Blood Pressure; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Echocardiography; Heart Failure; Hypertension; Male; Myocytes, Cardiac; Pyrazoles; Rats; Rats, Inbred SHR; Signal Transduction; Sodium-Hydrogen Exchangers; Thiazolidines; Vasodilation; Ventricular Remodeling | 2016 |
Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Blood Pressure; Cell Proliferation; China; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Receptors, Calcium-Sensing; Renin-Angiotensin System; Vascular Remodeling; Young Adult | 2016 |
Angiotensin II acting on PVN induces sympathoexcitation and pressor responses via the PI3K-dependent pathway.
Topics: Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Phosphatidylinositol 3-Kinases; Rats, Wistar; Sympathetic Nervous System; Vasoconstrictor Agents | 2016 |
Uric acid stimulates proliferative pathways in vascular smooth muscle cells through the activation of p38 MAPK, p44/42 MAPK and PDGFRβ.
Topics: Angiotensin II; Animals; Atherosclerosis; Cardiovascular Diseases; Cell Proliferation; Gene Expression Regulation; Humans; Hypertension; Hyperuricemia; Losartan; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; Receptor, Platelet-Derived Growth Factor beta; Uric Acid | 2017 |
Interaction between irbesartan, peroxisome proliferator-activated receptor (PPAR-γ), and adiponectin in the regulation of blood pressure and renal function in spontaneously hypertensive rats.
Topics: Adiponectin; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Gene Expression Regulation; Heart Rate; Hemodynamics; Hypertension; Injections, Intraperitoneal; Irbesartan; Kidney; Male; Methoxamine; Norepinephrine; Phenylephrine; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Signal Transduction; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents | 2016 |
Chronic p38 mitogen-activated protein kinase inhibition improves vascular function and remodeling in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Kidney; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Perfusion; Protein Kinase Inhibitors; S-Nitrosoglutathione; Systole; Vascular Remodeling | 2016 |
Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular Function.
Topics: Acetylcholine; Analysis of Variance; Angiotensin II; Animals; Carotid Arteries; Cerebral Arteries; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; Mice; Mice, Inbred C57BL; Nitroprusside; Random Allocation; Reference Values; rho-Associated Kinases; Vasoconstriction | 2016 |
Tert-butylhydroquinone lowers blood pressure in AngII-induced hypertension in mice via proteasome-PTEN-Akt-eNOS pathway.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hydroquinones; Hypertension; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase | 2016 |
ESTROGEN RELATED MECHANISMS OF HYPERTENSION IN MENOPAUSAL WOMEN.
Topics: Adult; Angiotensin II; Case-Control Studies; Endothelin-1; Estradiol; Estrogens; Female; Hemoglobins; Humans; Hypertension; Menopause; Middle Aged; Nitric Oxide | 2016 |
Qingxuan Jiangya Decoction Reverses Vascular Remodeling by Inducing Vascular Smooth Muscle Cell Apoptosis in Spontaneously Hypertensive Rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred SHR; Vascular Remodeling | 2016 |
On Endogenous Angiotensin II Antagonism in Hypertension: The Role of Dipeptidyl Peptidase III.
Topics: Angiotensin II; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Hypertension | 2016 |
Novel Therapeutic Role for Dipeptidyl Peptidase III in the Treatment of Hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Disease Models, Animal; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Hypertension; Mice; Mice, Inbred ICR; Random Allocation; Role; Sensitivity and Specificity; Treatment Outcome | 2016 |
Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Fibrosis; Genetic Predisposition to Disease; Hypertension; Male; Mice, Knockout; Muscle, Smooth, Vascular; Myocardium; NADPH Oxidases; Nitric Oxide Synthase Type III; Nitrites; Phenotype; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Stromal Interaction Molecule 1; Time Factors; Transcription Factor CHOP; Transforming Growth Factor beta; Vasodilation; Vasodilator Agents | 2016 |
Vascular peroxidase 1 up regulation by angiotensin II attenuates nitric oxide production through increasing asymmetrical dimethylarginine in HUVECs.
Topics: Amidohydrolases; Angiotensin II; Animals; Aorta; Arginine; Cells, Cultured; Endothelium, Vascular; Gene Knockdown Techniques; Hemeproteins; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypertension; Hypochlorous Acid; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxidases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Recombinant Proteins; RNA, Small Interfering; Up-Regulation | 2016 |
Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II.
Topics: ADAM17 Protein; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; ErbB Receptors; Fibrosis; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Myocytes, Cardiac; Random Allocation; Renin-Angiotensin System; Sensitivity and Specificity; Signal Transduction; Vascular Remodeling; Ventricular Remodeling | 2016 |
Neuroinflammatory mechanisms of hypertension: potential therapeutic implications.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cytokines; Humans; Hypertension; Inflammation; Lipopolysaccharides; Microglia; NF-kappa B; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Renin; Toll-Like Receptor 4 | 2016 |
Low dose ouabain stimulates NaK ATPase α1 subunit association with angiotensin II type 1 receptor in renal proximal tubule cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Hypertension; Kidney Tubules, Proximal; Mice; Ouabain; Peptidyl-Dipeptidase A; Phosphorylation; Protein Binding; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Transfection | 2016 |
Histone deacetylase and GATA-binding factor 6 regulate arterial remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Cycle Proteins; Cell Nucleus; Cell Proliferation; Cells, Cultured; DNA; GATA6 Transcription Factor; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Hypertension; Hypertrophy; Kidney; Male; Mice; Muscle, Smooth, Vascular; Phosphorylation; Pyrroles; Repressor Proteins; Vascular Remodeling | 2016 |
[Intervention of systolic pressure and left ventricular hypertrophy in rats under cold stress].
Topics: Angiotensin II; Animals; Benzazepines; Blood Pressure; Cold Temperature; Endothelin-1; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Inbred SHR; Stress, Physiological | 2016 |
Heterologous regulation of the cannabinoid type 1 receptor by angiotensin II in astrocytes of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Astrocytes; Blood Pressure; Cells, Cultured; Female; Hypertension; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Cannabinoid, CB1 | 2016 |
Oxidative stress increases the risk of pancreatic β cell damage in chronic renal hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Captopril; Deoxyguanosine; Diabetes Mellitus; Hypertension; Insulin; Insulin Secretion; Insulin-Secreting Cells; Kidney; Male; Models, Animal; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Pancreas; Rats; Rats, Sprague-Dawley; Thioctic Acid | 2016 |
Intracellular renin increases the inward calcium current in smooth muscle cells of mesenteric artery of SHR. Implications for hypertension and vascular remodeling.
Topics: Amides; Angiotensin II; Animals; Calcium; Calcium Signaling; Disease Models, Animal; Fumarates; Humans; Hypertension; Mesenteric Arteries; Myocytes, Smooth Muscle; Rats; Renin; Vascular Remodeling; Verapamil | 2016 |
A Disintegrin and Metalloprotease-17 Regulates Pressure Overload-Induced Myocardial Hypertrophy and Dysfunction Through Proteolytic Processing of Integrin β1.
Topics: ADAM17 Protein; Angiotensin II; Animals; Cardiomyopathy, Hypertrophic; Cells, Cultured; Disease Models, Animal; Disintegrins; Echocardiography, Doppler; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Myocytes, Cardiac; Proteolysis; Random Allocation; Rats; Ventricular Dysfunction, Left | 2016 |
Soy Pulp Extract Inhibits Angiotensin I-Converting Enzyme (ACE) Activity In Vitro: Evidence for Its Potential Hypertension-Improving Action.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chemical Fractionation; Chromatography, High Pressure Liquid; Glycine max; Humans; Hypertension; Peptides; Plant Extracts; Soybean Proteins | 2017 |
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 2016 |
Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction.
Topics: Angiotensin II; Animals; Aorta; Arterial Pressure; Blood Vessels; Cell Adhesion; Chemokine CCL2; Endothelium, Vascular; Gastrointestinal Microbiome; Germ-Free Life; Hypertension; Leukocytes; Mice; Monocytes; NADPH Oxidase 2; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Nuclear Receptor Subfamily 1, Group F, Member 3; Reactive Oxygen Species; RNA, Messenger | 2016 |
Letter by Zhou and Zhou Regarding Article, "Hypertension: Renin-Angiotensin-Aldosterone System Alterations".
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System | 2016 |
Response by Danser and van den Meiracker to Letter by Zhou and Zhou Regarding Article, "Hypertension: Renin-Angiotensin-Aldosterone System Alterations".
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System | 2016 |
Angiotensin II, hypertension and angiotensin II receptor antagonism: Roles in the behavioural and brain pathology of a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Blood Pressure; Brain; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Imidazoles; Maze Learning; Mice, Transgenic; Spatial Learning; Thiophenes | 2017 |
K+-Mediated Regulation of Distal Convoluted Tubule Na/Cl Cotransporter Phosphorylation During Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Hypertension; Kidney Tubules, Distal; Phosphorylation; Sodium; Solute Carrier Family 12, Member 3 | 2016 |
Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Infusions, Intravenous; Kidney Function Tests; Male; Multivariate Analysis; Phosphorylation; Potassium Deficiency; Potassium, Dietary; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Chloride Symporters; Sodium-Hydrogen Exchangers; Water-Electrolyte Balance | 2016 |
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
Topics: Aging; Alzheimer Disease; Angiotensin II; Animals; Biomarkers; Blood-Brain Barrier; Cognitive Dysfunction; Gene Expression; Hippocampus; Humans; Hypertension; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Microvascular Rarefaction; Neocortex; RNA, Messenger | 2016 |
Development of nonfibrotic left ventricular hypertrophy in an ANG II-induced chronic ovine hypertension model.
Topics: Angiotensin II; Animals; Autopsy; Fibrosis; Heart; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Models, Animal; Risk Factors; Sheep; Vasoconstrictor Agents; Ventricular Remodeling | 2016 |
Sulfur Dioxide Inhibits Extracellular Signal-regulated Kinase Signaling to Attenuate Vascular Smooth Muscle Cell Proliferation in Angiotensin II-induced Hypertensive Mice.
Topics: Angiotensin II; Animals; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Hypertension; Male; Mice; Muscle, Smooth, Vascular; Signal Transduction; Sulfur Dioxide | 2016 |
C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration.
Topics: Angiotensin II; Animals; Blood Pressure; Chemokine CCL2; Chemokine CCL5; Essential Hypertension; Female; Fibrosis; Hypertension; Kidney; Kidney Diseases; Macrophages; Male; Mice; Mice, Knockout; Nephrectomy; Renin-Angiotensin System; T-Lymphocytes; Ureteral Obstruction | 2016 |
Cholecalciferol treatment downregulates renin-angiotensin system and improves endothelial function in essential hypertensive patients with hypovitaminosid D.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Cardiovascular Diseases; Cholecalciferol; Endothelium; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Pulse Wave Analysis; Renin; Renin-Angiotensin System; Vasodilation; Vitamin D; Vitamin D Deficiency; Vitamins | 2016 |
Involvement of vascular peroxidase 1 in angiotensin II-induced hypertrophy of H9c2 cells.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Cell Line; Disease Models, Animal; Endothelium, Vascular; Gene Knockdown Techniques; Hemeproteins; Hydrogen Peroxide; Hypertension; Hypertrophy; Hypochlorous Acid; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NADPH Oxidase 2; Onium Compounds; Oxidative Stress; Peroxidases; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2017 |
The High Blood Pressure-Malaria Protection Hypothesis.
Topics: Africa; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Asia; Causality; Disease Resistance; Drug Evaluation, Preclinical; Endemic Diseases; Endothelium, Vascular; Humans; Hypertension; Malaria, Cerebral; Malaria, Falciparum; Mice; Models, Biological; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Prevalence; Receptor, Angiotensin, Type 2; Selection, Genetic | 2016 |
Renal denervation attenuates aldosterone expression and associated cardiovascular pathophysiology in angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Calcitonin Gene-Related Peptide; Cell Line, Tumor; Denervation; Heart; Humans; Hypertension; Kidney; Male; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction | 2016 |
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hydroxyproline; Hypertension; Male; Myocardium; Rats, Wistar; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2016 |
Central Angiotensin-II Increases Blood Pressure and Sympathetic Outflow via Rho Kinase Activation in Conscious Rabbits.
Topics: Analysis of Variance; Angiotensin II; Animals; Baroreflex; Consciousness; Disease Models, Animal; Hypertension; Male; Rabbits; Random Allocation; Renin-Angiotensin System; rho-Associated Kinases; Sympathetic Nervous System | 2016 |
Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular Dysfunction.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Male; Mice; Mice, Knockout; Receptors, Interleukin-8B; Up-Regulation; Vascular Remodeling | 2016 |
Astrocytes Contribute to Angiotensin II Stimulation of Hypothalamic Neuronal Activity and Sympathetic Outflow.
Topics: Angiotensin II; Animals; Astrocytes; Blotting, Western; Cells, Cultured; Electrophysiology; Glutamic Acid; Hypertension; Male; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Sympathetic Nervous System | 2016 |
Quantification of systemic renin-angiotensin system peptides of hypertensive black and white African men established from the RAS-Fingerprint®.
Topics: Adult; Angiotensin II; Black People; Humans; Hypertension; Male; Peptides; Renin-Angiotensin System; Statistics, Nonparametric; White People | 2016 |
Novel Biosensors Reveal a Shift in the Redox Paradigm From Oxidative to Reductive Stress in Heart Disease.
Topics: Angiotensin II; Antioxidants; Biosensing Techniques; Heart Diseases; Humans; Hypertension; Oxidation-Reduction; Oxidative Stress | 2016 |
Angiotensin II-Linked Hypothesis to Understand the Advantage of the Coevolution of Hypertension and Malaria: "Sympathy for the Devil".
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Malaria; Receptor, Angiotensin, Type 1 | 2016 |
Hypertension-Linked Pathophysiological Alterations in the Gut.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Gastrointestinal Microbiome; Hypertension; Intestinal Mucosa; Male; Permeability; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar | 2017 |
Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).
Topics: alpha-Globins; Angiotensin II; Animals; Blood Flow Velocity; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Humans; Hypertension; Mice; Nitric Oxide Synthase; Random Allocation; Vascular Resistance; Vasodilator Agents | 2016 |
Transcription factor PEX1 modulates extracellular matrix turnover through regulation of MMP-9 expression.
Topics: Adenoviridae; Aging; Angiotensin II; Animals; Animals, Newborn; Base Sequence; Extracellular Matrix; Fibroblasts; Fibrosis; Gene Expression Regulation; Gene Silencing; Gene Transfer Techniques; Hypertension; Matrix Metalloproteinase 9; Membrane Proteins; Models, Biological; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Promoter Regions, Genetic; Rats, Sprague-Dawley; Transcription Factors | 2017 |
Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension.
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Cognitive Dysfunction; Disease Models, Animal; Hypertension; Macrophages; Male; Membrane Glycoproteins; Mice; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1 | 2016 |
Use of Antihypertensive Drugs and Ischemic Stroke Severity - Is There a Role for Angiotensin-II?
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Brain Ischemia; Calcium Channel Blockers; Cross-Sectional Studies; Diuretics; Female; Humans; Hypertension; Malaysia; Male; Middle Aged; Multivariate Analysis; Registries; Severity of Illness Index; Stroke | 2016 |
Adipokine CTRP6 improves PPARγ activation to alleviate angiotensin II-induced hypertension and vascular endothelial dysfunction in spontaneously hypertensive rats.
Topics: Adipokines; Angiotensin II; Animals; Apoptosis; Blood Pressure; Brain; Cell Separation; Coronary Vessels; Endothelium, Vascular; Flavonoids; Flow Cytometry; Gene Silencing; Hypertension; Male; Mitogen-Activated Protein Kinase 3; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Wistar; RNA, Small Interfering; Signal Transduction | 2017 |
Structural and functional brain alterations in a murine model of Angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Brain; Disease Models, Animal; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Random Allocation | 2017 |
Protease-Activated Receptor 1 Contributes to Angiotensin II-Induced Cardiovascular Remodeling and Inflammation.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Coronary Vessels; Fibrosis; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptor, PAR-1; Signal Transduction; Vascular Remodeling | 2017 |
Macrophage-derived exosomes induce inflammatory factors in endothelial cells under hypertensive conditions.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Endothelial Cells; Exosomes; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Macrophages; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Wistar | 2017 |
Exercise modulates the aortic renin-angiotensin system independently of estrogen therapy in ovariectomized hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Estradiol; Estrogens; Exercise Therapy; Humans; Hypertension; Ovariectomy; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 2017 |
Increased mitochondrial superoxide in the brain, but not periphery, sensitizes mice to angiotensin II-mediated hypertension.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Brain; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Hypertension; Mice; Mitochondria; Organ Specificity; Oxidation-Reduction; Subfornical Organ; Superoxide Dismutase; Superoxides | 2017 |
Caveolin-1 Deletion Prevents Hypertensive Vascular Remodeling Induced by Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Caveolin 1; Disease Models, Animal; Gene Deletion; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2017 |
PGC-1α dictates endothelial function through regulation of eNOS expression.
Topics: Angiotensin II; Animals; Cell Line; Endothelial Cells; Estrogen Receptor alpha; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | 2016 |
Association of interleukin 17 / angiotensin II with refractory hypertension risk in hemodialysis patients.
Topics: Angiotensin II; Female; Humans; Hypertension; Interleukin-17; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Assessment | 2016 |
Chronic blockade of the AT2 receptor with PD123319 impairs insulin signaling in C57BL/6 mice.
Topics: Adiponectin; Adipose Tissue; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Chemokine CCL2; Diabetes Mellitus, Type 2; Humans; Hypertension; Imidazoles; Insulin; Insulin Resistance; Interleukin-6; Losartan; Mice; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 2; Signal Transduction; Tumor Necrosis Factor-alpha | 2017 |
Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity.
Topics: Angiotensin II; Animals; Arterial Pressure; Disease Models, Animal; Epithelial Sodium Channels; Gene Expression Regulation, Enzymologic; Hypertension; Kidney Tubules; Liver; Mice, Transgenic; Natriuresis; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Renal Elimination; Renin-Angiotensin System; Sodium Chloride, Dietary; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 3; Time Factors | 2017 |
Transient receptor potential vanilloid 2 function regulates cardiac hypertrophy via stretch-induced activation.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Calcium Channels; Constriction, Pathologic; Echocardiography; Heart; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Isoproterenol; Male; Mice; Mice, Knockout; Myocytes, Cardiac; Sarcolemma; TRPV Cation Channels; Up-Regulation; Vasoconstrictor Agents | 2017 |
Differential hypertensive protease expression in the thoracic versus abdominal aorta.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Cathepsin K; Cathepsin L; Cathepsins; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypertension; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; RNA, Messenger; Vascular Remodeling | 2017 |
Impaired Aortic Contractility to Uridine Adenosine Tetraphosphate in Angiotensin II-Induced Hypertensive Mice: Receptor Desensitization?
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Arterial Pressure; Blood Pressure; Dinucleoside Phosphates; Hypertension; Isometric Contraction; Losartan; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Receptor, Angiotensin, Type 1; Receptors, Purinergic P2X1; Vasoconstrictor Agents | 2017 |
Phosphodiesterase 5 inhibition ameliorates angiotensin II-dependent hypertension and renal vascular dysfunction.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphodiesterase 5 Inhibitors; Renal Artery; Renal Circulation; Sildenafil Citrate; Vasodilation; Vasodilator Agents; Vinca Alkaloids | 2017 |
Puerarin protects against endothelial dysfunction and end-organ damage in Ang II-induced hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; China; Endothelium, Vascular; Heart Ventricles; Hypertension; Isoflavones; Male; Membrane Glycoproteins; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Tunica Media; Vascular Cell Adhesion Molecule-1; Vasodilation; Vasodilator Agents | 2017 |
A novel complex I inhibitor protects against hypertension-induced left ventricular hypertrophy.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Blood Pressure; Electron Transport Complex I; Energy Metabolism; Enzyme Activators; Hypertension; Hypertrophy, Left Ventricular; In Vitro Techniques; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Vasoconstrictor Agents | 2017 |
Cellular Repressor of E1A-Stimulated Genes Is a Critical Determinant of Vascular Remodeling in Response to Angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Protein c-ets-1; Rats, Inbred Dahl; Recombinant Proteins; Repressor Proteins; RNA Interference; Signal Transduction; Sodium Chloride, Dietary; Time Factors; Transfection; Vascular Remodeling | 2017 |
Renal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II.
Topics: Angiotensin II; Animals; Down-Regulation; Hypertension; Kidney; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Sodium Chloride, Dietary | 2017 |
Assessment of Vascular Dysfunction and Inflammation Induced by Angiotensin II in Mice.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Blood Pressure Monitors; Cell Separation; Drug Administration Schedule; Endothelium, Vascular; Hypertension; Infusion Pumps, Implantable; Macrophages; Mice; Monocytes; Organ Culture Techniques; Osmotic Pressure; Vasculitis | 2017 |
Expression and localization of the AT
Topics: Angiotensin II; Animals; Aorta; Diabetes Mellitus, Experimental; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, alpha-1; Renin-Angiotensin System; Tunica Intima; Tunica Media | 2017 |
Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bone Marrow Transplantation; Cell Movement; Disease Models, Animal; Fingolimod Hydrochloride; Genetic Predisposition to Disease; Hypertension; Inflammation Mediators; Lymph Nodes; Lysophospholipids; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; T-Lymphocytes; Time Factors; Vascular Remodeling | 2017 |
Nicotinamide nucleotide transhydrogenase activity impacts mitochondrial redox balance and the development of hypertension in mice.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Carotid Arteries; Cells, Cultured; Disease Models, Animal; Endothelium; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Myography; NADP Transhydrogenase, AB-Specific; Nitric Oxide; Organophosphorus Compounds; Oxidation-Reduction; Oxidative Stress; Piperidines; Primary Cell Culture; Superoxide Dismutase; Superoxides; Vasoconstrictor Agents | 2017 |
RACK1 regulates angiotensin II-induced contractions of SHR preglomerular vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Membrane; Cells, Cultured; Disease Models, Animal; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; GTP-Binding Proteins; Hypertension; Juxtaglomerular Apparatus; Male; Microvessels; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neuropeptide Y; Phospholipase C beta; Protein Binding; Protein Transport; Rats, Inbred SHR; Rats, Inbred WKY; Receptors for Activated C Kinase; RNA Interference; Signal Transduction; Transfection; Vasoconstriction; Vasoconstrictor Agents | 2017 |
Positive association between KCNJ5 rs2604204 (A/C) polymorphism and plasma aldosterone levels, but also plasma renin and angiotensin I and II levels, in newly diagnosed hypertensive Chinese: a case-control study.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure Monitoring, Ambulatory; Case-Control Studies; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gene Frequency; Genotype; Humans; Hypertension; Logistic Models; Male; Middle Aged; Polymorphism, Single Nucleotide; Renin | 2017 |
Demethoxycurcumin Preserves Renovascular Function by Downregulating COX-2 Expression in Hypertension.
Topics: Acetylcholine; Aged; Angiotensin II; Animals; Blood Pressure; Celecoxib; Curcuma; Curcumin; Cyclooxygenase 2; Diarylheptanoids; Down-Regulation; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Male; Microscopy, Fluorescence; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Up-Regulation; Vasoconstriction | 2016 |
In Vivo Analysis of Hypertension: Induction of Hypertension, In Vivo Kinase Manipulation, and Assessment of Physiologic Outputs.
Topics: Angiotensin II; Animals; ErbB Receptors; Hypertension; Immunohistochemistry; Mice; Phosphorylation; Renin-Angiotensin System; Signal Transduction | 2017 |
TRPM8 downregulation by angiotensin II in vascular smooth muscle cells is involved in hypertension.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Down-Regulation; Hydrogen Peroxide; Hypertension; Male; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; TRPM Cation Channels | 2017 |
Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension.
Topics: Aged; Angiotensin II; Animals; Blood Coagulation; Blood Platelets; Blood Pressure; Factor XI; Female; Humans; Hypertension; Macrophage-1 Antigen; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Oligonucleotides, Antisense; Platelet Glycoprotein GPIb-IX Complex; Rats, Wistar; Thrombin; Thromboplastin; Vascular Cell Adhesion Molecule-1 | 2017 |
Endoplasmic reticulum stress inhibition attenuates hypertensive chronic kidney disease through reduction in proteinuria.
Topics: Angiotensin II; Animals; Apoptosis; Biopsy; Blood Pressure; Disease Models, Animal; Endoplasmic Reticulum Stress; Fibrosis; Gene Expression Profiling; Humans; Hypertension; Inflammation; Male; Mice; Mice, Knockout; Nephrosclerosis; Phenylbutyrates; Proteinuria; Renal Insufficiency, Chronic; Transcription Factor CHOP; Transcriptome; Urinalysis | 2017 |
Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regulation; Hypertension; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Remodeling | 2017 |
Intracellular Staining and Flow Cytometry to Identify Lymphocyte Subsets within Murine Aorta, Kidney and Lymph Nodes in a Model of Hypertension.
Topics: Angiotensin II; Animals; Aorta; Cytokines; Disease Models, Animal; Flow Cytometry; Hypertension; Kidney; Lymph Nodes; Mice; Staining and Labeling; T-Lymphocyte Subsets | 2017 |
The phosphoinositide-3 kinase signaling is involved in neuroinflammation in hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cytokines; Dose-Response Relationship, Drug; Encephalitis; Heart Rate; Humans; Hypertension; Lipopolysaccharides; Male; Medulla Oblongata; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Small Interfering; Signal Transduction; Sympathetic Nervous System | 2017 |
Increased Aldosterone Release During Head-Up Tilt in Early Primary Hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Case-Control Studies; Heart Rate; Humans; Hypertension; Male; Posture; Predictive Value of Tests; Renin; Renin-Angiotensin System; Tilt-Table Test; Time Factors; Up-Regulation; Vascular Resistance; Young Adult | 2017 |
Association between circulating angiotensin-converting enzyme 2 and cardiac remodeling in hypertensive patients.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme 2; Blood Pressure; Echocardiography; Female; Heart; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2017 |
Maternal Gestational Hypertension-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Renal Denervation or Angiotensin-Converting Enzyme Inhibition in Rat Offspring.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Blood Pressure; Disease Models, Animal; Female; Hypertension; Hypertension, Pregnancy-Induced; Kidney; Male; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathectomy | 2017 |
Primate response to angiotensin infusion and high sodium intake differ by sodium lithium countertransport phenotype.
Topics: Angiotensin II; Animals; Antiporters; Blood Pressure; Hypertension; Male; Papio hamadryas; Phenotype; Renin-Angiotensin System; Sodium, Dietary | 2017 |
Elevated Serotonin Interacts with Angiotensin-II to Result in Altered Valve Interstitial Cell Contractility and Remodeling.
Topics: Angiotensin II; Animals; Aortic Valve; Blood Pressure; Cell Proliferation; Cells, Cultured; Cytoskeleton; Disease Models, Animal; Female; Fibrillar Collagens; Fibrosis; Heart Valve Diseases; Hypertension; Mechanotransduction, Cellular; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Serotonin; Stroke Volume; Sus scrofa; Ventricular Function, Left | 2018 |
Cardiac Fibroblast-Specific Activating Transcription Factor 3 Protects Against Heart Failure by Suppressing MAP2K3-p38 Signaling.
Topics: Acetylation; Activating Transcription Factor 3; Angiotensin II; Animals; Binding Sites; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Genetic Predisposition to Disease; Heart Failure; Histone Deacetylase 1; Histones; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; MAP Kinase Kinase 3; Mice, Knockout; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenotype; Promoter Regions, Genetic; Protein Kinase Inhibitors; Signal Transduction; Time Factors; Transforming Growth Factor beta; Ventricular Function, Left; Ventricular Remodeling | 2017 |
Vascular transcriptome profiling identifies Sphingosine kinase 1 as a modulator of angiotensin II-induced vascular dysfunction.
Topics: Angiotensin II; Animals; Aortic Dissection; Gene Expression Profiling; Hypertension; Male; Mice; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor) | 2017 |
miR-185/P2Y6 Axis Inhibits Angiotensin II-Induced Human Aortic Vascular Smooth Muscle Cell Proliferation.
Topics: Angiotensin II; Aorta; Cell Proliferation; Cells, Cultured; Down-Regulation; HEK293 Cells; Humans; Hypertension; MAP Kinase Signaling System; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, Purinergic P2; Vascular Diseases | 2017 |
Overexpressed connective tissue growth factor in cardiomyocytes attenuates left ventricular remodeling induced by angiotensin II perfusion.
Topics: Actins; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Collagen Type I; Connective Tissue Growth Factor; Echocardiography; Fibrosis; Heart; Heart Ventricles; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Vasoconstrictor Agents; Ventricular Remodeling | 2017 |
Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
Topics: Aging; Angiotensin II; Animals; Cerebral Hemorrhage; Disease Models, Animal; Extracellular Matrix; Gait; Hypertension; Infusion Pumps, Implantable; Insulin-Like Growth Factor I; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Oxidative Stress; Phenotype; Psychomotor Performance | 2017 |
Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Electron Spin Resonance Spectroscopy; Endothelial Cells; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; NADPH Oxidase 2; NADPH Oxidases | 2017 |
Regulation of myosin light chain kinase expression by angiotensin II in hypertension.
Topics: Angiotensin II; Animals; Aorta; Azepines; Blood Pressure; Cells, Cultured; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Hypertension; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Naphthalenes; ras Proteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Signal Transduction; Vasoconstrictor Agents | 2008 |
Heme oxygenase-1 expression is down-regulated by angiotensin II and under hypertension in human neutrophils.
Topics: Angiotensin II; Cell Culture Techniques; Down-Regulation; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Humans; Hypertension; Neutrophils; Nitric Oxide Synthase Type II; Prostaglandin D2; Reference Values | 2008 |
[Immunization against angiotensin II--pro].
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Immunization; Immunization Schedule; Immunization, Secondary | 2008 |
[Immunization against angiotensin II--contra].
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Immunization; Renin-Angiotensin System | 2008 |
Angiotensin II-induced hypertension differentially affects estrogen and progestin receptors in central autonomic regulatory areas of female rats.
Topics: Angiotensin II; Animals; Autonomic Nervous System; Catecholamines; Disease Models, Animal; Female; Gene Expression Regulation; Hypertension; Hypothalamus; Infusion Pumps, Implantable; Medulla Oblongata; Microscopy, Immunoelectron; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Tyrosine 3-Monooxygenase | 2008 |
Bibliography. Current world literature. Hypertension.
Topics: Adrenergic beta-Antagonists; Aging; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Cannabinoid Receptor Modulators; Diabetes Complications; Endothelin-1; Genetic Therapy; Heart; Humans; Hypertension; Peptidyl-Dipeptidase A; Pharmacogenetics; Social Class; Sodium Chloride, Dietary; Stress, Physiological | 2008 |
The flame that lights the fire: oxidative stress, inflammation, and renal damage in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypertension; Inflammation; Inflammation Mediators; Kidney Diseases; Mice; Mice, Knockout; Oxidative Stress | 2008 |
Role of inflammation in the development of renal damage and dysfunction in angiotensin II-induced hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Blotting, Western; Cell Movement; Cell Proliferation; Disease Models, Animal; Glomerular Filtration Rate; Hypertension; Immunohistochemistry; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrosclerosis; Probability; Random Allocation; Reactive Oxygen Species; Receptors, Chemokine; Reference Values; Sensitivity and Specificity | 2008 |
Angiotensinogen genotype predicts abnormal renal hemodynamics in young hypertensive patients.
Topics: Adult; Age Factors; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Female; Genotype; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Renal Circulation; Renin-Angiotensin System; Vasoconstrictor Agents | 2008 |
Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Angiotensin II; Animals; Cells, Cultured; Enzyme Inhibitors; Hypertension; Mesenteric Arteries; Muscle, Smooth, Vascular; NADPH Oxidases; Oxidation-Reduction; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; RNA, Small Interfering; Signal Transduction | 2008 |
High intraluminal pressure via H2O2 upregulates arteriolar constrictions to angiotensin II by increasing the functional availability of AT1 receptors.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Angiotensin II; Animals; Antioxidants; Arterioles; Blood Pressure; Catalase; Hydrogen Peroxide; Hypertension; In Vitro Techniques; Male; Muscle, Skeletal; Oxidative Stress; Polyethylene Glycols; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Up-Regulation; Vasoconstriction | 2008 |
Inactivation of G(i) proteins by pertussis toxin diminishes the effectiveness of adrenergic stimuli in conduit arteries from spontaneously hypertensive rats.
Topics: Acetylcholine; Adrenergic Agents; Angiotensin II; Animals; Aorta, Thoracic; Arteries; Blood Pressure; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; In Vitro Techniques; Male; Mesenteric Artery, Superior; Norepinephrine; Pertussis Toxin; Pulmonary Artery; Rats; Rats, Inbred SHR; Signal Transduction | 2008 |
Characterization of angiotensin II antagonism displayed by Ib, a novel nonpeptide angiotensin AT(1) receptor antagonist.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Cattle; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Injections, Intravenous; Liver; Losartan; Male; Protein Binding; Pyrroles; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Time Factors; Triazoles; Vasoconstriction | 2008 |
Intrarenal angiotensin II and angiotensinogen augmentation in chronic angiotensin II-infused mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Organ Size; Receptor, Angiotensin, Type 1; Renin | 2008 |
Oxidative stress mediates cardiac fibrosis by enhancing transforming growth factor-beta1 in hypertensive rats.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Collagen Type I; Fibroblasts; Fibrosis; Gene Expression Regulation; Hypertension; Immunohistochemistry; Membrane Glycoproteins; Models, Biological; Myocardium; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Rats; RNA, Messenger; Systole; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta1 | 2008 |
Agonistic AT(1) receptor autoantibody increases in serum of patients with refractory hypertension and improves Ca(2+) mobilization in cultured rat vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autoantibodies; Calcium; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Immunologic; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2008 |
Central estrogen inhibition of angiotensin II-induced hypertension in male mice and the role of reactive oxygen species.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Data Interpretation, Statistical; Estradiol; Estrogens; Fulvestrant; Hypertension; Injections, Intraventricular; Irbesartan; Male; Mice; Microscopy, Confocal; Oxidative Stress; Reactive Oxygen Species; Spin Labels; Subfornical Organ; Telemetry; Tetrazoles | 2008 |
Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK.
Topics: Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Blood Pressure; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Infusion Pumps, Implantable; Inhalation Exposure; Male; Myosin Light Chains; NADPH Oxidases; Nitric Oxide Synthase; Particle Size; Particulate Matter; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Time Factors; Vasoconstriction | 2008 |
Area-specific differences in transmitter release in central catecholaminergic neurons of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Brain Stem; Catecholamines; Disease Models, Animal; Dopamine beta-Hydroxylase; Electrophysiology; Hypertension; Losartan; Neurons; Norepinephrine; Phenethylamines; Probability; Random Allocation; Rats; Rats, Inbred SHR; Rats, Wistar; Reference Values; Sensitivity and Specificity | 2008 |
Oxidative stress-induced renal angiotensin AT1 receptor upregulation causes increased stimulation of sodium transporters and hypertension.
Topics: Angiotensin II; Animals; Buthionine Sulfoximine; Enzyme Activation; Hypertension; Inositol 1,4,5-Trisphosphate; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium-Potassium-Exchanging ATPase; Type C Phospholipases; Up-Regulation | 2008 |
Pioglitazone inhibits angiotensin II-induced senescence of endothelial progenitor cell.
Topics: Angiotensin II; Cells, Cultured; Cellular Senescence; Drug Interactions; Gene Expression; Hematopoietic Stem Cells; Humans; Hypertension; Hypoglycemic Agents; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Pioglitazone; Receptor, Angiotensin, Type 1; Superoxides; Telomerase; Thiazolidinediones; Vasoconstrictor Agents | 2008 |
Exaggerated blood pressure response to exercise is associated with augmented rise of angiotensin II during exercise.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Bicycling; Blood Pressure; Case-Control Studies; Catecholamines; Diastole; Exercise; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Neurotransmitter Agents; Renin; Stroke Volume | 2008 |
Prevention of aortic fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Collagen; Elastin; Enzyme Activation; Fibrosis; Heart Diseases; Hypertension; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lipid Metabolism; Male; Neutrophil Infiltration; Oligopeptides; Oxidation-Reduction; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Smad2 Protein; Transforming Growth Factor beta1; Vasoconstrictor Agents | 2008 |
Modulation of angiotensin II-mediated hypertension and cardiac remodeling by lectin-like oxidized low-density lipoprotein receptor-1 deletion.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Fibroblasts; Gene Deletion; Gene Expression; Hypertension; Mice; Mice, Knockout; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Oxidative Stress; Receptor, Angiotensin, Type 1; Scavenger Receptors, Class E; Vasoconstrictor Agents; Ventricular Remodeling | 2008 |
Cardiac metabolic compensation to hypertension requires lipoprotein lipase.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Desoxycorticosterone; Fatty Acids; Glucose; Glycogen; Hypertension; Lipid Metabolism; Lipids; Lipoprotein Lipase; Mice; Mice, Knockout; Myocardium; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Triglycerides | 2008 |
Perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure sensitizes offspring to angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Carcinogens, Environmental; Cardiomegaly; Collagen; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Gestational Age; Hypertension; Kidney; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidases; Polychlorinated Dibenzodioxins; Pregnancy; Prenatal Exposure Delayed Effects; Procollagen; Renin-Angiotensin System; RNA, Messenger; Telemetry; Time Factors; Ultrasonography | 2008 |
Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzoates; Benzyl Compounds; Blood Pressure; Calcium; Cell Survival; CHO Cells; Cinnamates; Cricetinae; Cricetulus; HeLa Cells; Humans; Hypertension; Liquidambar; Magnetic Resonance Spectroscopy; Male; Mice; Receptor, Angiotensin, Type 1; Spectrometry, Mass, Electrospray Ionization | 2008 |
Cardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopause.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Blotting, Western; Cardiomegaly; Collagen; Disease Models, Animal; Female; Follicle Stimulating Hormone; Hypertension; MAP Kinase Kinase Kinase 5; Menopause; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Oxidative Stress; Phosphorylation; Receptor, Angiotensin, Type 1; Signal Transduction; Superoxide Dismutase; Thioredoxins; Time Factors | 2008 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressure; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Humans; Hydralazine; Hypertension; Inflammation; Male; NADPH Oxidases; Neurons; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Sodium Chloride; Stroke; Tetrazoles; Valine; Valsartan | 2008 |
Kidney-specific induction of heme oxygenase-1 prevents angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Induction; Heme; Heme Oxygenase-1; Hypertension; Infusion Pumps; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Protoporphyrins; Spectrophotometry; Treatment Outcome | 2008 |
Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Heart Rate; Humans; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mutation; Myocytes, Cardiac; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Stroke Volume; Time Factors; Ventricular Remodeling | 2009 |
Enhanced angiotensin II type 2 receptor mechanisms mediate decreases in arterial pressure attributable to chronic low-dose angiotensin II in female rats.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Heart Ventricles; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Vasodilation | 2008 |
The effect of recombinant aminopeptidase A on hypertension in spontaneously hypertensive rats: its effect in comparison with candesartan.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Baculoviridae; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Genetic Vectors; Glutamyl Aminopeptidase; Humans; Hypertension; Male; Mutation; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Recombinant Proteins; Tetrazoles | 2008 |
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy.
Topics: Angiotensin II; Animals; Blood Pressure; Capillaries; Cardiomegaly; Cardiomyopathies; Cell Size; Ceramides; Coronary Vessels; Disease Models, Animal; Heart Rate; Humans; Hypertension; Lipid Metabolism; Mice; Mice, Transgenic; Mitochondria, Heart; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Neovascularization, Physiologic; Oxidation-Reduction; Promoter Regions, Genetic; Skin; Time Factors; Triglycerides; Up-Regulation; Vascular Endothelial Growth Factor B; Ventricular Function, Left; Ventricular Myosins | 2008 |
Role of the median preoptic nucleus in chronic angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cardiovascular System; Chronic Disease; Excitatory Amino Acid Agonists; Hypertension; Ibotenic Acid; Injections, Intraventricular; Male; Neurons; Preoptic Area; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2008 |
Role of Menkes ATPase in angiotensin II-induced hypertension: a key modulator for extracellular superoxide dismutase function.
Topics: Acetylcholine; Adenosine Triphosphatases; Angiotensin II; Animals; Antioxidants; Aorta; Blood Pressure; Cation Transport Proteins; Copper-Transporting ATPases; Cyclic N-Oxides; Disease Models, Animal; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Spin Labels; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Vasodilation | 2008 |
Contrasting effect of exercise and angiotensin II hypertension on in vivo and in vitro cardiac angiogenesis in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Capillaries; Carotid Arteries; Coronary Vessels; Echocardiography; Heart; Heart Rate; Heart Ventricles; Hypertension; Male; Myocardium; Neovascularization, Physiologic; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents | 2008 |
Inhibition of Ang II and renal sympathetic nerve influence dopamine-and isoprenaline-induced renal haemodynamic changes in normal Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Dopamine; Hemodynamics; Hypertension; Isoproterenol; Kidney; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Renin-Angiotensin System; Sodium; Species Specificity; Sympathectomy; Sympathetic Nervous System; Sympathomimetics | 2008 |
Cardioprotective effects of granulocyte colony-stimulating factor in angiotensin II-induced cardiac remodelling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Granulocyte Colony-Stimulating Factor; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Myocardium; Osteopontin; Peptidyl-Dipeptidase A; Phosphorylation; Recombinant Proteins; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Ventricular Function, Left; Ventricular Remodeling | 2009 |
[Impact of different emulated acupuncture-needle manipulations on blood pressure and myocardial angiotensin II content in spontaneous hypertension rats].
Topics: Acupuncture Points; Acupuncture Therapy; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Myocardium; Random Allocation; Rats; Rats, Inbred SHR | 2008 |
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Blood Pressure; Cardiomegaly; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Muscle, Smooth, Vascular; Nitroprusside; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Vasodilator Agents | 2008 |
Microsomal prostaglandin synthase-1-derived prostaglandin E2 protects against angiotensin II-induced hypertension via inhibition of oxidative stress.
Topics: Angiotensin II; Animals; Cells, Cultured; Female; Hypertension; Intramolecular Oxidoreductases; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mice, Mutant Strains; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Prostaglandin-E Synthases; Reactive Oxygen Species; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction | 2008 |
The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension.
Topics: Angiotensin II; Animals; Arteries; Calcium; Calcium Channels, L-Type; Humans; Hypertension; Mice; Mice, Knockout; Muscle, Smooth, Vascular; NFATC Transcription Factors; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Signal Transduction | 2008 |
Nerve stimulation induced overflow of neuropeptide Y and modulation by angiotensin II in spontaneously hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Captopril; Disease Models, Animal; Electric Stimulation; Hypertension; Imidazoles; Mesenteric Arteries; Neuropeptide Y; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Splanchnic Circulation; Sympathetic Nervous System | 2008 |
Chronic actions of a novel oral B-type natriuretic peptide conjugate in normal dogs and acute actions in angiotensin II-mediated hypertension.
Topics: Administration, Oral; Amino Acid Sequence; Angiotensin II; Animals; Dogs; Drug Administration Schedule; Hypertension; Male; Molecular Sequence Data; Natriuretic Peptide, Brain; Random Allocation | 2008 |
Inflammation, angiotensin II, and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Immunosuppressive Agents; Inflammation; Mice; Mice, Knockout; Oxidative Stress; Rats; Rats, Inbred Dahl; Receptors, CCR2 | 2008 |
Electrocortical activation induced by abrupt increases in blood pressure in "pontine" cats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Brain Ischemia; Cats; Cerebrovascular Circulation; Electroencephalography; Electromyography; Epinephrine; Flowmeters; Hypertension; Hypotension; Ligation; Physical Stimulation; Pons; Vagotomy | 1973 |
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Crosses, Genetic; Heart; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Ventricular Remodeling | 2008 |
Activation of renin-angiotensin system induces osteoporosis independently of hypertension.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Bone Remodeling; Humans; Hypertension; Mice; Osteoblasts; Osteoporosis; RANK Ligand; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Vascular Endothelial Growth Factor A | 2009 |
A pilot study on level of blood vasoactive factors in prehypertensive and hypertensive patients.
Topics: Adrenomedullin; Adult; Angiotensin II; Arginine Vasopressin; Blood Pressure; Calcitonin Gene-Related Peptide; Case-Control Studies; Endothelins; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Nitric Oxide Synthase; Pilot Projects | 2008 |
Genetically hypertensive Brown Norway congenic rat strains suggest intermediate traits underlying genetic hypertension.
Topics: Angiotensin II; Animals; Animals, Congenic; Blood Pressure; Disease Models, Animal; Female; Genetic Linkage; Genetic Markers; Hypertension; Male; Phenotype; Pressoreceptors; Quantitative Trait Loci; Rats; Rats, Inbred BN; Risk Factors | 2008 |
Inhibition of angiotensin II Gq signaling augments beta-adrenergic receptor mediated effects in a renal artery stenosis model of high blood pressure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Echocardiography; Female; GTP-Binding Protein alpha Subunits, Gq-G11; Hemodynamics; Hypertension; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Receptors, Adrenergic, beta; Renal Artery Obstruction; Signal Transduction | 2009 |
A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Circadian Rhythm; Genetic Predisposition to Disease; Haplotypes; Humans; Hypertension; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Renin; RNA, Messenger; Transcription, Genetic | 2008 |
Regulatory effect of hydrogen sulfide on vascular collagen content in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cell Division; Collagen Type I; Hydrogen Sulfide; Hydroxyproline; Hypertension; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Thymidine; Tritium; Vasoconstrictor Agents | 2008 |
Networking between systemic angiotensin II and cardiac mineralocorticoid receptors.
Topics: Angiotensin II; Animals; Humans; Hypertension; Hypertrophy, Left Ventricular; Myocardium; Receptors, Mineralocorticoid; Renin-Angiotensin System | 2008 |
Cross-talk between mineralocorticoid and angiotensin II signaling for cardiac remodeling.
Topics: Angiotensin II; Animals; Blood Pressure; Echocardiography; Female; Heart Failure; Humans; Hypertension; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Oxidative Stress; Pregnancy; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Signal Transduction; Vasoconstrictor Agents; Ventricular Remodeling | 2008 |
Angiotensin II-induced hypertension is associated with a selective inhibition of endothelium-derived hyperpolarizing factor-mediated responses in the rat mesenteric artery.
Topics: Acetylcholine; Angiotensin II; Animals; Biological Factors; Blood Pressure; Hypertension; Male; Mesenteric Arteries; Muscle Relaxation; Rats; Rats, Wistar | 2009 |
Role of NOX2 in the regulation of afferent arteriole responsiveness.
Topics: Acetophenones; Adenosine; Angiotensin II; Animals; Arterioles; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney Cortex; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Renal Circulation; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Angiotensins; Animals; Cells, Cultured; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; Hypertension; Hyperuricemia; KATP Channels; Kidney; Kidney Diseases; Male; Nitric Oxide; Oxonic Acid; Propylamines; Rats; Rats, Sprague-Dawley; Urate Oxidase; Uric Acid; Xanthine Oxidase | 2008 |
Candesartan ameliorates cardiac dysfunction observed in angiotensin-converting enzyme 2-deficient mice.
Topics: Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Disease Models, Animal; Echocardiography; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardium; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Tetrazoles | 2008 |
Actions of aldosterone in the cardiovascular system: the good, the bad, and the ugly?
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiovascular System; ErbB Receptors; Homeostasis; Hypertension; Inflammation; Receptors, Mineralocorticoid; Signal Transduction | 2009 |
Benazepril, an angiotensin-converting enzyme inhibitor, alleviates renal injury in spontaneously hypertensive rats by inhibiting advanced glycation end-product-mediated pathways.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Disease Models, Animal; Female; Glycation End Products, Advanced; Hypertension; Kidney Cortex; Kidney Diseases; Male; NADPH Oxidases; Oxidative Stress; Phosphorylation; Platelet-Derived Growth Factor; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction; Transcription Factor RelA; Transforming Growth Factor beta1; Vascular Cell Adhesion Molecule-1 | 2009 |
The angiotensin converting enzyme 2/Ang-(1-7) axis in the heart: a role for MAS communication?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiomegaly; Female; Heart; Humans; Hypertension; Male; Mice; Mice, Knockout; Models, Animal; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2008 |
Increased transient receptor potential canonical type 3 channels in vasculature from hypertensive rats.
Topics: Amlodipine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Benzimidazoles; Benzoates; Blood Pressure; Calcium; Calcium Channel Blockers; Cells, Cultured; Gene Expression Regulation; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Telmisartan; TRPC Cation Channels; Vasoconstrictor Agents | 2009 |
Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelin A Receptor Antagonists; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hypertension; Insulin; Losartan; Male; Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Receptor, Endothelin A; Streptozocin; Vasoconstriction | 2008 |
Roles of endothelial oxidases in endothelium-derived hyperpolarizing factor responses in mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biological Factors; Blood Pressure; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glutathione Peroxidase; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidoreductases; Superoxide Dismutase; Superoxides; Vasodilation; Vasodilator Agents | 2008 |
Experimental induction of salt-sensitive hypertension is associated with lymphocyte proliferative response to HSP70.
Topics: Angiotensin II; Animals; Autoimmunity; Cell Proliferation; Cells, Cultured; Disease Models, Animal; HSP70 Heat-Shock Proteins; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Sprague-Dawley; Salt Tolerance; T-Lymphocytes | 2008 |
Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Betamethasone; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetal Development; Glucocorticoids; Hypertension; Kidney Tubules, Proximal; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Sheep | 2009 |
Relation of blood pressure quantitative trait locus on rat chromosome 1 to hyperactivity of rostral ventrolateral medulla.
Topics: Angiotensin II; Animals; Animals, Congenic; Blood Pressure; Chromosomes; Electrophysiological Phenomena; Hypertension; Hypothalamus; Medulla Oblongata; Membrane Potentials; Neurons; Patch-Clamp Techniques; Quantitative Trait Loci; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Channel Blockers; Tetrodotoxin; Vasoconstrictor Agents | 2009 |
Angiotensin-converting enzyme-derived angiotensin II formation during angiotensin II-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Lisinopril; Male; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A | 2009 |
Oral contraceptive-induced high blood pressure is prevented by renin-angiotensin suppression in female rats but not by sympathetic nervous system blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Clonidine; Contraceptives, Oral; Dose-Response Relationship, Drug; Female; Hypertension; Models, Biological; Norepinephrine; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathetic Nervous System; Treatment Outcome | 2008 |
Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Arterioles; Calcium Channels; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Hydrolysis; Hypertension; Male; Mesentery; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation Coupling Factors; Proton-Translocating ATPases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; src-Family Kinases; Time Factors; Vascular Resistance; Vasoconstriction | 2009 |
Substitution of connexin40 with connexin45 prevents hyperreninemia and attenuates hypertension.
Topics: Angiotensin II; Animals; Connexins; Gap Junction alpha-5 Protein; Gene Knock-In Techniques; Genetic Therapy; Hypertension; Juxtaglomerular Apparatus; Kidney; Mice; Mice, Knockout; Renin | 2009 |
Administration of angiotensin II, but not catecholamines, induces accumulation of lipids in the rat heart.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Gene Expression; Hypertension; Lipid Metabolism; Lipids; Male; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Superoxides | 2009 |
The Ca(v)3.2 T-type Ca(2+) channel is required for pressure overload-induced cardiac hypertrophy in mice.
Topics: Angiotensin II; Animals; Animals, Newborn; Aorta; Blood Pressure; Calcineurin; Calcium Channel Blockers; Calcium Channels, T-Type; Calcium Signaling; Cardiomegaly; Cells, Cultured; Constriction; Disease Models, Animal; Ethosuximide; Genes, Reporter; Hypertension; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NFATC Transcription Factors; Time Factors | 2009 |
Plasma kallikrein mediates angiotensin II type 1 receptor-stimulated retinal vascular permeability.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood-Retinal Barrier; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Hypertension; Kallikreins; Kinins; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Retinal Artery; Streptozocin; Tetrazoles | 2009 |
Hypertension in mice lacking the CXCR3 chemokine receptor.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Hypertension; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Antagonists; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Receptor, Muscarinic M3; Receptors, CXCR3; Sodium Chloride; Sp1 Transcription Factor; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Endothelin-1 modulates angiotensin II in the development of hypertension in fructose-fed rats.
Topics: Angiotensin II; Animals; Blood Pressure; Dietary Carbohydrates; Endothelin-1; Fructose; Glucose Tolerance Test; Hypertension; Imidazoles; Immunohistochemistry; Insulin Resistance; Male; Rats; Rats, Wistar; Tetrazoles | 2009 |
Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles.
Topics: Acute Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cell Fractionation; Cell Membrane; Cytoplasmic Vesicles; Disease Models, Animal; Diuresis; Hypertension; Infusions, Intravenous; Kidney Tubules, Distal; Male; Microscopy, Immunoelectron; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sodium Chloride Symporters; Solute Carrier Family 12, Member 3; Symporters; Time Factors | 2009 |
p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Hypertension; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; RNA, Messenger; Superoxides | 2009 |
Exendin-4 has an anti-hypertensive effect in salt-sensitive mice model.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Exenatide; Glucagon-Like Peptide-1 Receptor; Hypertension; Kidney; Male; Mice; Mice, Inbred Strains; Peptides; Receptors, Glucagon; Sodium Chloride, Dietary; Venoms | 2009 |
Role of angiotensin II and oxidative stress in vascular insulin resistance linked to hypertension.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; C-Reactive Protein; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Insulin; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Signal Transduction; Sodium Chloride, Dietary; Spin Labels; Superoxide Dismutase; Tetrazoles; Vasodilation; Vasodilator Agents | 2009 |
Influence of sympathetic and AT-receptor blockade on angiotensin II and adrenergic agonist-induced renal vasoconstrictions in spontaneously hypertensive rats.
Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carbazoles; Carvedilol; Drug Interactions; Hypertension; Kidney; Losartan; Male; Propanolamines; Rats; Rats, Inbred SHR; Renal Circulation; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Cardiovascular and autonomic phenotype of db/db diabetic mice.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Cardiovascular System; Circadian Rhythm; Diabetes Complications; Diabetes Mellitus, Type 2; Disease Models, Animal; Heart Rate; Hypertension; Losartan; Male; Mice; Mice, Mutant Strains; Motor Activity; Peptidyl-Dipeptidase A; Phenotype; Receptor, Angiotensin, Type 1; Receptors, Leptin | 2009 |
Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway.
Topics: Angiotensin II; Animals; Hyperkalemia; Hypertension; Hypovolemia; Kidney; Mice; Oocytes; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Sodium Chloride Symporters; Transfection; Xenopus | 2009 |
Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Cytokines; Hypertension; Inflammation Mediators; Male; NADPH Oxidases; NF-kappa B; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Proline; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Spin Labels; Superoxides; Sympathetic Nervous System; Thiocarbamates | 2009 |
Angiotensin II induces renal plasminogen activator inhibitor-1 and cyclooxygenase-2 expression post-transcriptionally via activation of the mRNA-stabilizing factor human-antigen R.
Topics: Angiotensin II; Animals; Antigens, Surface; Cyclooxygenase 2; ELAV Proteins; ELAV-Like Protein 1; Electrophoretic Mobility Shift Assay; Fibrosis; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Hypertension; Immunohistochemistry; Immunoprecipitation; Kidney Diseases; Male; Plasminogen Activator Inhibitor 1; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Messenger | 2009 |
ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol, Dietary; Disease Models, Animal; Hydralazine; Hypercholesterolemia; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Receptors, LDL; Risk Factors; Time Factors | 2009 |
Rosuvastatin protects against angiotensin II-induced renal injury in a dose-dependent fashion.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Collagen Type IV; Disease Models, Animal; Dose-Response Relationship, Drug; Fibronectins; Fluorescent Antibody Technique, Indirect; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Kidney Cortex; Kidney Medulla; Male; Monocytes; Necrosis; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Rosuvastatin Calcium; Sulfonamides | 2009 |
Strain-dependent differences of restraint stress-induced hypertension in WKY and SHR.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Gene Expression Regulation; Heart Rate; Hypertension; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Restraint, Physical; RNA, Messenger; Species Specificity; Tyrosine 3-Monooxygenase | 2009 |
Angiotensin II-induced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Signaling; Collagen Type IV; Extracellular Matrix; Eye; Eye Proteins; Gene Expression Regulation; Hypertension; Macular Degeneration; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retinal Pigment Epithelium; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2 | 2009 |
Coronary flow reserve: a new target for treating hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Humans; Hypertension; Risk Factors | 2009 |
Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Atmosphere Exposure Chambers; Blood Pressure; Cardiomegaly; Collagen; Disease Models, Animal; Guanine Nucleotide Exchange Factors; Hypertension; Infusion Pumps; Inhalation Exposure; Injections, Intraperitoneal; Male; Matrix Metalloproteinases, Secreted; Mice; Mice, Inbred C57BL; Myocardium; Particulate Matter; Protein Kinase Inhibitors; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstriction; Vasodilation; Ventricular Remodeling | 2009 |
Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Diabetes Mellitus; Dinoprostone; Disease Models, Animal; Hypertension; Male; Mice; Mice, Mutant Strains; Muscle, Skeletal; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Vascular Resistance; Vasoconstrictor Agents; Xanthones | 2009 |
Acquisition of brain Na sensitivity contributes to salt-induced sympathoexcitation and cardiac dysfunction in mice with pressure overload.
Topics: Anesthesia, General; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain; Disease Models, Animal; Epinephrine; Epithelial Sodium Channels; Heart; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Infusions, Parenteral; Male; Mice; Mice, Inbred ICR; Microfilament Proteins; Myocardial Contraction; Norepinephrine; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Sodium Channel Blockers; Sodium Chloride, Dietary; Sympathetic Nervous System; Telemetry; Time Factors | 2009 |
Endothelial damage due to impaired nitric oxide bioavailability triggers cerebral aneurysm formation in female rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Base Sequence; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Corrosion Casting; DNA Primers; Endothelium, Vascular; Estradiol; Estrogen Replacement Therapy; Female; Humans; Hypertension; Intracranial Aneurysm; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Ovariectomy; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles | 2009 |
Altered nitric oxide calcium responsiveness of aortic smooth muscle cells in spontaneously hypertensive rats depends on low expression of cyclic guanosine monophosphate-dependent protein kinase type I.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Base Sequence; Calcium Signaling; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; DNA Primers; Green Fluorescent Proteins; Hypertension; In Vitro Techniques; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Recombinant Proteins; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Transfection | 2009 |
Aldosterone blockade by Spironolactone improves the hypertensive vascular hypertrophy and remodeling in angiotensin II overproducing transgenic mice.
Topics: Aldosterone; Angiotensin II; Animals; Female; Hyperplasia; Hypertension; Hypertrophy; Male; Mice; Mice, Transgenic; Mineralocorticoid Receptor Antagonists; Osteopontin; Renin-Angiotensin System; Spironolactone; Tunica Intima | 2009 |
Impairment of the autoregulation of renal hemodynamics and of the pressure-natriuresis relationship precedes the development of hypertension in Cyp1a1-Ren-2 transgenic rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cytochrome P-450 CYP1A1; Glomerular Filtration Rate; Hemodynamics; Homeostasis; Hypertension; Indoles; Kidney; Losartan; Male; Natriuresis; Rats; Rats, Transgenic; Receptor, Angiotensin, Type 1; Renal Circulation; Renin; Renin-Angiotensin System; Sodium; Time Factors | 2009 |
Renal functional, not morphological, abnormalities account for salt sensitivity in Dahl rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cyclic GMP; Diastole; Dose-Response Relationship, Drug; Fibrosis; Glomerulosclerosis, Focal Segmental; Hemodynamics; Hypertension; Kidney; Kidney Glomerulus; Kidney Medulla; Organ Size; Proteinuria; Rats; Rats, Inbred Dahl; Sodium; Sodium Chloride, Dietary; Systole; Time Factors; Vascular Resistance; Vasoconstriction | 2009 |
Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Brain; Citrulline; Enzyme Inhibitors; Heart Failure; Hypertension; Kidney; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pressoreceptors; Rats; Rats, Inbred Dahl; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Thiourea | 2009 |
AT(1) receptor activation regulates the mRNA expression of CAT1, CAT2, arginase-1, and DDAH2 in preglomerular vessels from angiotensin II hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arginase; Arterioles; Calcium Channels; Disease Models, Animal; Hypertension; Kidney Glomerulus; Losartan; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; TRPV Cation Channels | 2009 |
Impact of early onset obesity and hypertension on the unfolded protein response in renal tissues of juvenile sheep.
Topics: Analysis of Variance; Angiotensin II; Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; Disease Progression; Female; Hypertension; Immunohistochemistry; Kidney; Kidney Diseases; Male; Nitric Oxide; Obesity; Proteins; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Sheep; Statistics, Nonparametric; Tissue Culture Techniques | 2009 |
NaCl plus chitosan as a dietary salt to prevent the development of hypertension in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Chitosan; Chlorides; Creatinine; Heart; Histocytochemistry; Hypertension; Kidney; Male; Potassium; Potassium Chloride; Random Allocation; Rats; Rats, Inbred SHR; Sodium; Sodium Chloride, Dietary; Systole | 2009 |
Mitochondrial Thioredoxin: novel regulator for NADPH oxidase and angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Mice; Mice, Transgenic; Mitochondria; NADPH Oxidases; Random Allocation; Reactive Oxygen Species; Sensitivity and Specificity; Thioredoxins | 2009 |
Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of Thioredoxin 2.
Topics: Analysis of Variance; Angiotensin II; Animals; Animals, Newborn; Blood Pressure Determination; Cardiomegaly; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxygen Consumption; Random Allocation; Reactive Oxygen Species; Reference Values; Risk Factors; Thioredoxins; Vascular Resistance; Vasoconstriction; Vasodilation | 2009 |
Ventral lamina terminalis mediates enhanced cardiovascular responses of rostral ventrolateral medulla neurons during increased dietary salt.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure Determination; Cardiovascular Diseases; Disease Models, Animal; Hemodynamics; Hypertension; Hypothalamus; Male; Medulla Oblongata; Neural Inhibition; Neurons; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors; Sensitivity and Specificity; Sodium Chloride, Dietary; Sympathetic Nervous System | 2009 |
Enhanced responses to ganglion blockade do not reflect sympathetic nervous system contribution to angiotensin II-induced hypertension.
Topics: Adenosine; Angiotensin II; Animals; Blood Pressure; Denervation; Ganglionic Blockers; Hindlimb; Hypertension; Kidney; Nitroprusside; Norepinephrine; Pentolinium Tartrate; Rabbits; Regional Blood Flow; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 2009 |
[Hypertensiology 2009].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; Drug Therapy, Combination; Electric Stimulation; England; Germany; Health Promotion; Humans; Hypertension; Kidney; Physicians, Family; Pressoreceptors; Salaries and Fringe Benefits; Sodium Chloride, Dietary; Sympathectomy; Telemetry; Vaccines | 2009 |
Biglycan expression in hypertensive subjects with normal or increased carotid intima-media wall thickness.
Topics: Adult; Angiotensin II; Biglycan; C-Reactive Protein; Carotid Arteries; Case-Control Studies; Extracellular Matrix Proteins; Female; Gene Expression Regulation; Humans; Hypertension; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Monocytes; Proteoglycans; Regression Analysis; RNA, Messenger; Tumor Necrosis Factor-alpha; Tunica Intima | 2009 |
Na(+)-ATPase in spontaneous hypertensive rats: possible AT(1) receptor target in the development of hypertension.
Topics: Angiotensin II; Animals; Enzyme Activation; Hypertension; Kidney Tubules, Proximal; Kinetics; Losartan; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Sodium-Potassium-Exchanging ATPase | 2010 |
Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice.
Topics: Angiotensin II; Animals; Bilirubin; Blood Pressure; Cardiomegaly; Disease Models, Animal; Glucuronosyltransferase; Hyperbilirubinemia; Hypertension; Indinavir; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitrites; Organic Cation Transport Proteins; Oxidative Stress | 2009 |
Angiotensin-(1-7) antagonist, A-779, microinjection into the caudal ventrolateral medulla of renovascular hypertensive rats restores baroreflex bradycardia.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradycardia; Heart Rate; Hypertension; Losartan; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Inbred F344 | 2009 |
Direct action of an angiotensin II receptor blocker on angiotensin II-induced left atrial conduction delay in spontaneously hypertensive rats.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Electric Stimulation; Heart Atria; Heart Conduction System; Hypertension; Imidazoles; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 2009 |
Independent and combined influence of AGTR1 variants and aerobic exercise on oxidative stress in hypertensives.
Topics: Aged; Alleles; Angiotensin II; Blood Pressure; Exercise; Female; Genotype; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Polymorphism, Genetic; Receptor, Angiotensin, Type 1 | 2009 |
Elevating blood pressure as a strategy to increase tumor-targeted delivery of macromolecular drug SMANCS: cases of advanced solid tumors.
Topics: Adenocarcinoma; Adult; Aged; Angiotensin II; Antineoplastic Agents; Blood Pressure; Carcinoma, Renal Cell; Cholangiocarcinoma; Drug Delivery Systems; Female; Humans; Hypertension; Infusions, Intravenous; Japan; Kidney Neoplasms; Liver Neoplasms; Male; Maleic Anhydrides; Middle Aged; Neoplasm Staging; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Polystyrenes; Vasoconstrictor Agents; Zinostatin | 2009 |
Tyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Biopterins; Blood Pressure; Cells, Cultured; Cysteine Proteinase Inhibitors; Endothelial Cells; Endothelium, Vascular; GTP Cyclohydrolase; Humans; Hypertension; In Vitro Techniques; Leupeptins; Mice; Mice, Inbred C57BL; Nitrates; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; RNA, Small Interfering; Transfection; Tyrosine; Vasodilation | 2009 |
Comparative antihypertensive activities of losartan and HM70186 in rats with hepatic dysfunction.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Liver Diseases; Losartan; Male; Rats; Rats, Wistar; Time Factors | 2009 |
Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Arteries; Hypertension; Imidazoles; Immunohistochemistry; In Vitro Techniques; Male; Muscle Relaxation; NADPH Oxidases; Peptidyl-Dipeptidase A; Protective Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renin; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Tetrazoles; Valine; Valsartan; Vascular Diseases | 2009 |
Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.
Topics: Angiotensin II; Animals; Cell Line; Collagen Type I; Connective Tissue Growth Factor; Disease Models, Animal; Epithelial Cells; Hypertension; Kidney Diseases; Kidney Tubules; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta; Up-Regulation | 2009 |
Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Hypertension; Infusions, Intravenous; Male; Middle Cerebral Artery; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Vasodilation; Vasodilator Agents | 2009 |
Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Heart Diseases; Heart Ventricles; Hypertension; Hypertrophy; Inflammation; Macrophages; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta; Ventricular Remodeling | 2009 |
Spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice.
Topics: Acute Disease; Angiotensin II; Animals; Blood Pressure; Chronic Disease; Fluorescent Antibody Technique; Gelatin; Hypertension; Immunohistochemistry; Intracranial Hemorrhages; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Norepinephrine; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Stroke; Vasoconstrictor Agents | 2010 |
Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Cyclooxygenase 2; Dietary Fats; Endothelium, Vascular; Hypertension; I-kappa B Kinase; Insulin Resistance; Kidney; Lipids; Male; Nephritis; NF-kappa B; Nitrites; Obesity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents; Weight Gain | 2010 |
Protective actions of estrogen on angiotensin II-induced hypertension: role of central nitric oxide.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Estrogens; Female; Ganglionic Blockers; Hexamethonium; Hypertension; Immunohistochemistry; Infusion Pumps, Implantable; Infusions, Subcutaneous; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Orchiectomy; Ornithine; Ovariectomy; Paraventricular Hypothalamic Nucleus; Receptors, Estrogen; Sex Factors; Subfornical Organ; Sympathetic Nervous System; Telemetry; Time Factors; Up-Regulation | 2009 |
Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.
Topics: Angiotensin II; Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Disease Models, Animal; GABA Agonists; GABA Antagonists; Hypertension; Infusion Pumps, Implantable; Male; Microinjections; Muscimol; NG-Nitroarginine Methyl Ester; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Time Factors; Up-Regulation | 2009 |
Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Antioxidants; Blood Pressure; Blood Vessels; Catalase; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Homeostasis; Humans; Hydrogen Peroxide; Hypertension; Imidazoles; Ion Channels; Male; Medulla Oblongata; Microinjections; Mitochondria; Mitochondrial Proteins; NADPH Oxidases; Onium Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Rosiglitazone; Spin Labels; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Sympathetic Nervous System; Thiazolidinediones; Time Factors; Transcription Factors; Transcriptional Activation; Transduction, Genetic; Uncoupling Protein 2; Up-Regulation | 2009 |
Biomarkers of inflammation and endothelial dysfunction and risk of hypertension among Inner Mongolians in China.
Topics: Adult; Angiotensin II; Asian People; Biomarkers; Blood Pressure; Blood Proteins; C-Reactive Protein; China; Cross-Sectional Studies; E-Selectin; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Male; Middle Aged; Renin; Risk Factors | 2010 |
Attenuation of angiotensin II-induced hypertension and cardiac hypertrophy in transgenic mice overexpressing a type 1 receptor mutant.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Hypertension; Mice; Mice, Transgenic; Protein Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; rhoA GTP-Binding Protein | 2009 |
Prenatal dehydration alters renin-angiotensin system associated with angiotensin-increased blood pressure in young offspring.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Baroreflex; Birth Weight; Blood Pressure; Female; Fetal Development; Gene Expression; Heart; Heart Rate; Hypertension; Liver; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Water Deprivation | 2009 |
Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Bartter Syndrome; Cells, Cultured; Drug Combinations; Dual Specificity Phosphatase 1; Female; Fibroblasts; Gitelman Syndrome; Humans; Hypertension; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2010 |
Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II.
Topics: Adenoviridae; Angiotensin II; Animals; Brain Chemistry; Disease Models, Animal; Drinking; Gene Expression Regulation; Genetic Vectors; Hypertension; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NADPH Oxidases; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Superoxides | 2009 |
[Establishment of a diabetic-hypertensive rat model].
Topics: Angiotensin II; Angiotensinogen; Animals; Aorta; Blood Pressure Determination; Diabetes Mellitus, Experimental; Endothelin-1; Hypertension; Kidney; Male; Rats; Rats, Wistar | 2009 |
Early diabetes in WKY and SHR produces decrease of the responses to angiotensin II and 5-HT and changes in the NO-GMPc pathway.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Cyclic GMP; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Nitric Oxide; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Signal Transduction; Streptozocin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Regular exercise produced cardioprotective effects on rat's heart with hypertension induced by L-NAME administration.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Body Weight; Disease Models, Animal; Heart; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Physical Conditioning, Animal; Rats | 2009 |
Clopidogrel, independent of the vascular P2Y12 receptor, improves arterial function in small mesenteric arteries from AngII-hypertensive rats.
Topics: Acetylcholine; Adenosine Diphosphate; Angiotensin II; Animals; Blotting, Western; Clopidogrel; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Purinergic P2Y Receptor Antagonists; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides; Ticlopidine; Vasodilation; Vasodilator Agents | 2010 |
Evidence that nitric oxide inhibits vascular inflammation and superoxide production via a p47phox-dependent mechanism in mice.
Topics: Angiotensin II; Animals; Aorta; Atherosclerosis; Blood Pressure; Enzyme Inhibitors; Glycosylation; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Reactive Oxygen Species; Superoxides; Time Factors; Vascular Cell Adhesion Molecule-1; Vasculitis | 2010 |
Intrarenal mouse renin-angiotensin system during ANG II-induced hypertension and ACE inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Disease Models, Animal; Hypertension; Kidney; Lisinopril; Male; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 2010 |
Blood pressure and renal blow flow responses in heme oxygenase-2 knockout mice.
Topics: Administration, Oral; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); Hypertension; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Renal Circulation; Vascular Resistance; Vasoconstriction | 2009 |
Effect of acute increase in blood pressure on intraocular pressure in pigs and humans.
Topics: Adult; Angiotensin II; Animals; Blood Pressure; Carbon Dioxide; Exercise; Female; Heart Rate; Humans; Hypertension; Intraocular Pressure; Male; Nitroprusside; Partial Pressure; Swine; Tonometry, Ocular; Vasoconstrictor Agents; Vasodilator Agents; Young Adult | 2010 |
Shift to an involvement of phosphatidylinositol 3-kinase in angiotensin II actions on nucleus tractus solitarii neurons of the spontaneously hypertensive rat.
Topics: Action Potentials; Angiotensin II; Animals; Baroreflex; Cells, Cultured; Disease Models, Animal; Heart; Hypertension; Microinjections; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Reproducibility of Results; Signal Transduction; Solitary Nucleus; Sympathetic Nervous System; Transduction, Genetic | 2009 |
PPARalpha stimulation exerts a blood pressure lowering effect through different mechanisms in a time-dependent manner.
Topics: Angiotensin II; Animals; Antioxidants; Aortic Coarctation; Blood Pressure; Clofibrate; Gene Expression Regulation; Hypertension; Lipid Peroxidation; Male; Nitric Oxide Synthase Type III; Oxidoreductases; PPAR alpha; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Angiotensin; Superoxide Dismutase; Time Factors | 2010 |
Protection of angiotensin II-induced vascular hypertrophy in vascular smooth muscle-targeted receptor activity-modifying protein 2 transgenic mice.
Topics: Adrenomedullin; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Female; Hypertension; Hypertrophy; Hypotension; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Vasculitis | 2009 |
Losartan-antioxidant hybrids: novel molecules for the prevention of hypertension-induced cardiovascular damage.
Topics: Alcohols; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Pressure; Cardiovascular Diseases; Cells, Cultured; Collagen Type I; Esters; Fibronectins; Humans; Hypertension; Losartan; Male; Oxidative Stress; Rats; Rats, Wistar | 2009 |
NADPH oxidase isoforms and anti-hypertensive effects of atorvastatin demonstrated in two animal models.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Apolipoproteins E; Atorvastatin; Blood Pressure; Blotting, Western; Dietary Fats; Ethidium; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase; Pyrroles; rac1 GTP-Binding Protein; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Role of angiotensin II Type 1A receptors in cardiovascular reactivity and neuronal activation after aversive stress in mice.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Blood Vessels; Heart Rate; Hypertension; Immunohistochemistry; Mice; Mice, Mutant Strains; Motor Activity; Proto-Oncogene Proteins c-fos; Receptor, Angiotensin, Type 1; Stress, Physiological; Tachycardia; Telemetry | 2009 |
Elastase-induced intracranial aneurysms in hypertensive mice.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Enzyme Inhibitors; Hypertension; Injections; Intracranial Aneurysm; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Subarachnoid Space; Vasoconstrictor Agents | 2009 |
Gender differences in angiotensin II and aldosterone secretion in patients with pressure overloaded systemic right ventricles are similar to those observed in systemic arterial hypertension.
Topics: Adolescent; Aldosterone; Angiotensin II; Biomarkers; Blood Pressure; Female; Humans; Hypertension; Immunoradiometric Assay; Male; Prospective Studies; Sex Characteristics; Transposition of Great Vessels; Ventricular Dysfunction, Right; Young Adult | 2011 |
Lack of glutathione peroxidase 1 accelerates cardiac-specific hypertrophy and dysfunction in angiotensin II hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Blotting, Western; Body Weight; Cardiomegaly; Echocardiography; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Heart; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Ventricular Dysfunction, Left | 2010 |
Influence of hypercholesterolemia and hypertension on the integrity of the blood-brain barrier in rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood-Brain Barrier; Body Weight; Catalase; Cholesterol; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutathione; Hypercholesterolemia; Hypertension; Lipoproteins, LDL; Male; Malondialdehyde; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphoproteins; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Zonula Occludens-1 Protein | 2009 |
Angiotensin-converting enzyme 2: a new target for neurogenic hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Baroreflex; Blood Pressure; Hypertension; Mice; Mice, Transgenic; Nitric Oxide Synthase; Peptidyl-Dipeptidase A | 2010 |
Chymase: the other ACE?
Topics: Angiotensin II; Animals; Chymases; Diabetes Complications; Diabetic Nephropathies; Disease Models, Animal; Humans; Hypertension; Kidney; Mice; Peptidyl-Dipeptidase A; Receptors, Leptin; Signal Transduction | 2010 |
Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Baroreflex; Blood Pressure; Blotting, Western; Brain; Brain Stem; Female; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide; Nitric Oxide Synthase; Parasympathetic Nervous System; Peptide Fragments; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Inappropriately high circulating and intrarenal angiotensin II levels during dietary salt loading exacerbate hypertension in Cyp1a1-Ren-2 transgenic rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Creatinine; Cytochrome P-450 CYP1A1; Hypertension; Kidney; Male; Rats; Rats, Transgenic; Renin; Sodium Chloride, Dietary | 2010 |
A vaccine for hypertension based on peptide AngI-R: a pilot study.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Hypertension; Isoantibodies; Male; Pilot Projects; Rabbits; Random Allocation; Rats; Rats, Inbred SHR; Vaccines, Subunit | 2011 |
Alteration of perivascular adipose tissue function in angiotensin II-induced hypertension.
Topics: Adipose Tissue; Angiotensin II; Animals; Aorta, Thoracic; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Rate; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Wistar; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Infusion Pumps; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins | 2010 |
Mechanisms of blood pressure reduction by prolonged activation of the baroreflex.
Topics: Afferent Pathways; Angiotensin II; Animals; Baroreflex; Blood Pressure; Clinical Trials as Topic; Disease Models, Animal; Dogs; Electric Stimulation Therapy; Humans; Hypertension; Nerve Fibers | 2009 |
Hyperuricemia, cardiovascular disease, and the metabolic syndrome.
Topics: Angiotensin II; Cardiovascular Diseases; Humans; Hypertension; Hyperuricemia; Metabolic Syndrome; Obesity; Renin-Angiotensin System; Risk Factors; Uric Acid | 2009 |
A role for angiotensin II type 1 receptors on bone marrow-derived cells in the pathogenesis of angiotensin II-dependent hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Bone Marrow Cells; Bone Marrow Transplantation; Cell Movement; Chemokine CCL2; Female; Gene Expression; Hypertension; Kidney; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Transplantation Chimera | 2010 |
Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3',5'-cyclic monophosphate-dependent pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Calcium; Cardiomegaly; Cell Size; Cells, Cultured; Cyclic GMP; Hypertension; Microscopy, Confocal; Myocytes, Cardiac; NFATC Transcription Factors; Nitric Oxide; Peptide Fragments; Protein Transport; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Signal Transduction | 2010 |
Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat.
Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Fumarates; Glomerular Filtration Rate; Hypertension; Irbesartan; Kidney; Membrane Glycoproteins; Membrane Proteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Podocytes; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles; Tyrosine | 2010 |
Angiotensin II, oxidant signaling, and hypertension: down to a T?
Topics: Angiotensin II; Humans; Hypertension; Oxidative Stress; Reactive Oxygen Species; Sensitivity and Specificity; Signal Transduction; T-Lymphocytes | 2010 |
Induction of hypertension and peripheral inflammation by reduction of extracellular superoxide dismutase in the central nervous system.
Topics: Adenoviridae; Angiotensin II; Animals; Blood Pressure Determination; Central Nervous System; Disease Models, Animal; Heart Rate; Hypertension; Inflammation; Inflammation Mediators; Integrases; Mice; Mice, Inbred C57BL; Oxidative Stress; Random Allocation; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase | 2010 |
Autonomic dysregulation in ob/ob mice is improved by inhibition of angiotensin-converting enzyme.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Disease Models, Animal; Fourier Analysis; Hypertension; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2010 |
Angiotensin II induces a region-specific hyperplasia of the ascending aorta through regulation of inhibitor of differentiation 3.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Hyperplasia; Hypertension; Inhibitor of Differentiation Proteins; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Norepinephrine; Organ Specificity; Receptor, Angiotensin, Type 1; Renin; Tunica Media | 2010 |
Effect of pomegranate juice on Angiotensin II-induced hypertension in diabetic Wistar rats.
Topics: Angiotensin II; Animals; Blood Pressure; Catalase; Colon; Diabetes Mellitus, Experimental; Fruit; Glutathione Reductase; Hypertension; Lythraceae; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2010 |
Early life stress sensitizes rats to angiotensin II-induced hypertension and vascular inflammation in adult life.
Topics: Angiotensin II; Animals; Animals, Newborn; Baroreflex; Blood Pressure Determination; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Infusions, Intravenous; Male; Random Allocation; Rats; Rats, Inbred WKY; Reference Values; Renin-Angiotensin System; Stress, Psychological; Vasculitis; Vasoconstrictor Agents | 2010 |
Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Cohort Studies; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Humans; Hypertension; Interleukin-17; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Probability; Random Allocation; Reference Values; T-Lymphocytes; Vascular Diseases | 2010 |
Sympathetic nervous system modulation of inflammation and remodeling in the hypertensive heart.
Topics: Analysis of Variance; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypertension; Inflammation Mediators; Male; Myocytes, Cardiac; Probability; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Sympathectomy; Sympathetic Nervous System; Ventricular Remodeling | 2010 |
Syndecan-1 amplifies angiotensin II-induced cardiac fibrosis.
Topics: Angiotensin II; Animals; Blotting, Western; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hypertension; Male; Mice; Mice, Inbred BALB C; Myocardium; Probability; Random Allocation; RNA, Messenger; Smad2 Protein; Syndecan-1 | 2010 |
Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.
Topics: 8,11,14-Eicosatrienoic Acid; Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Evaluation, Preclinical; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Multiple Organ Failure; Norepinephrine; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renal Circulation; Sulfones; Vasoconstrictor Agents | 2010 |
Dietary salt enhances angiotensin-II-induced superoxide formation in the rostral ventrolateral medulla.
Topics: Angiotensin II; Animals; Hypertension; Male; Medulla Oblongata; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium Chloride, Dietary; Superoxides | 2010 |
Angiotensin II inhibits neuronal nitric oxide synthase activation through the ERK1/2-RSK signaling pathway to modulate central control of blood pressure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Enzyme Activation; Flavonoids; Hypertension; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Ribosomal Protein S6 Kinases; Signal Transduction; Solitary Nucleus; Spin Labels; Time Factors | 2010 |
Angiotensin-(1-7) improves cardiac remodeling and inhibits growth-promoting pathways in the heart of fructose-fed rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dietary Carbohydrates; Disease Models, Animal; Fructose; Hypertension; Hypertrophy, Left Ventricular; Insulin; Insulin Resistance; Male; Peptide Fragments; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2010 |
The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.
Topics: Albuminuria; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Dinoprostone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hypertension; Intramolecular Oxidoreductases; Kidney; Mice; Mice, Inbred DBA; Mice, Knockout; Microsomes; Probability; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Effect of prenatal dexamethasone on postnatal serum and urinary angiotensin II levels.
Topics: Angiotensin II; Animals; Creatinine; Dexamethasone; Female; Hypertension; Kidney; Male; Maternal Exposure; Postpartum Period; Pregnancy; Rats; Rats, Sprague-Dawley | 2010 |
Regulatory polymorphism in transcription factor KLF5 at the MEF2 element alters the response to angiotensin II and is associated with human hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Aorta; Atherosclerosis; Case-Control Studies; Cells, Cultured; Chromatin Immunoprecipitation; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypertension; Immunoblotting; Immunoenzyme Techniques; Immunoprecipitation; Kruppel-Like Transcription Factors; MADS Domain Proteins; Male; MEF2 Transcription Factors; Middle Aged; Myogenic Regulatory Factors; p38 Mitogen-Activated Protein Kinases; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Rats; Reactive Oxygen Species; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction | 2010 |
The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Guanine Nucleotide Exchange Factors; Hypertension; Janus Kinase 2; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Phosphorylation; Proto-Oncogene Proteins; Rho Guanine Nucleotide Exchange Factors; Signal Transduction; Tyrosine | 2010 |
Receptor activity-modifying protein 1 increases baroreflex sensitivity and attenuates Angiotensin-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Nervous System Diseases; Baroreflex; Blood Pressure; Calcitonin Gene-Related Peptide; Gene Expression; Heart Rate; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Losartan; Male; Membrane Proteins; Mice; Mice, Transgenic; Parasympathetic Nervous System; Phenotype; Receptor Activity-Modifying Protein 1; Receptor Activity-Modifying Proteins; Receptor, Angiotensin, Type 1; Vasoconstrictor Agents | 2010 |
Chronic angiotensin II infusion causes differential responses in regional sympathetic nerve activity in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Chronic Disease; Heart Rate; Hindlimb; Hypertension; Kidney; Lumbosacral Region; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sympathetic Nervous System; Vasoconstrictor Agents | 2010 |
Tubuloglomerular feedback is decreased in COX-1 knockout mice after chronic angiotensin II infusion.
Topics: Angiotensin II; Animals; Cyclooxygenase 1; Gene Expression Regulation, Enzymologic; Hypertension; Kidney Glomerulus; Kidney Tubules; Male; Membrane Proteins; Mice; Mice, Knockout; Prostaglandins | 2010 |
Lymphocyte responses exacerbate angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Body Weight; Cardiomegaly; Crosses, Genetic; Disease Progression; Heart; Hemodynamics; Hypertension; Kidney; Lymphocytes; Mice; Mice, Inbred C3H; Mice, SCID; Organ Size; RNA, Messenger | 2010 |
T lymphocytes mediate hypertension and kidney damage in Dahl salt-sensitive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Dahl; Renin; Serum Albumin; T-Lymphocytes | 2010 |
Citrus limetta leaves extract antagonizes the hypertensive effect of angiotensin II.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Citrus; Clinical Trials as Topic; Dosage Forms; Humans; Hypertension; Male; Mexico; Mice; Mice, Inbred ICR; Plant Leaves; Random Allocation; Telmisartan | 2010 |
Critical role for copper/zinc-superoxide dismutase in preventing spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Cerebral Hemorrhage; Enzyme Activation; Humans; Hypertension; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidases; Oxidative Stress; Superoxide Dismutase; Superoxides | 2010 |
Simultaneous determination of angiotensins II and 1-7 by capillary zone electrophoresis in plasma and urine from hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Hypertension; Limit of Detection; Linear Models; Male; Peptide Fragments; Rats; Rats, Wistar; Temperature | 2010 |
C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; C-Reactive Protein; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart; Heart Rate; Humans; Hypertension; Immunohistochemistry; Inflammation; Interleukin-1beta; Mice; Myocardium; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad Proteins; Tumor Necrosis Factor-alpha; Up-Regulation; Ventricular Remodeling | 2010 |
A novel p38 MAPK target dyxin is rapidly induced by mechanical load in the heart.
Topics: Adenoviridae; Angiotensin II; Animals; Carrier Proteins; Co-Repressor Proteins; Gene Transfer Techniques; Genetic Vectors; Heart; Heart Ventricles; Hypertension; In Vitro Techniques; LIM Domain Proteins; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Mechanical; Vasoconstrictor Agents; Ventricular Remodeling | 2010 |
Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Astrocytes; Biosensing Techniques; Blood Pressure; Calcium Signaling; Catecholamines; Disease Models, Animal; Genes, Reporter; Hypertension; Losartan; Medulla Oblongata; Membrane Potentials; Microscopy, Confocal; Patch-Clamp Techniques; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Tissue Culture Techniques | 2010 |
Pentosan polysulfate treatment preserves renal autoregulation in ANG II-infused hypertensive rats via normalization of P2X1 receptor activation.
Topics: Actins; Adenosine Triphosphate; Angiotensin II; Animals; Anti-Inflammatory Agents; Arterioles; Blood Pressure; Disease Models, Animal; Homeostasis; Hypertension; Kidney; Male; Pentosan Sulfuric Polyester; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X1; Transforming Growth Factor beta1; Vasoconstriction | 2010 |
[Effect of electroacupuncture of different acupoints on blood pressure, plasma angiotensin II, aldosterone and atrial natriuretic peptide in spontaneous hypertension rats].
Topics: Acupuncture Points; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Animal; Electroacupuncture; Humans; Hypertension; Male; Random Allocation; Rats; Rats, Wistar | 2009 |
Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
Topics: Aminopropionitrile; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Dissection; Blood Pressure; Desoxycorticosterone; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mineralocorticoids; Protein-Lysine 6-Oxidase | 2010 |
A mechanism for salt-sensitive hypertension: abnormal dietary sodium-mediated vascular response to angiotensin-II.
Topics: Adult; Angiotensin II; Blood Pressure; Case-Control Studies; Diet, Sodium-Restricted; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2010 |
AT1 receptor blockade prevents the increase in blood pressure and the augmentation of intrarenal ANG II levels in hypertensive Cyp1a1-Ren2 transgenic rats fed with a high-salt diet.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cytochrome P-450 CYP1A1; Hypertension; Kidney; Losartan; Male; Mice; Rats; Rats, Transgenic; Receptor, Angiotensin, Type 1; Renin; Sodium Chloride, Dietary | 2010 |
Does enhanced respiratory-sympathetic coupling contribute to peripheral neural mechanisms of angiotensin II-salt hypertension?
Topics: Angiotensin II; Animals; Hypertension; Losartan; Medulla Oblongata; Rats; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary; Sympathetic Nervous System | 2010 |
Prenatal exposure to inflammation induced by zymosan results in activation of intrarenal renin-angiotensin system in adult offspring rats.
Topics: Angiotensin II; Animals; Blood Pressure; Creatinine; Female; Gene Expression; Hypertension; Inflammation; Kidney Function Tests; Kidney Glomerulus; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; RNA, Messenger; Zymosan | 2010 |
Smad3 mediates cardiac inflammation and fibrosis in angiotensin II-induced hypertensive cardiac remodeling.
Topics: Angiotensin II; Animals; Chemokine CCL2; Echocardiography; Gene Deletion; Hypertension; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Smad3 Protein; Stroke Volume; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2010 |
Sex chromosome effects unmasked in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Crosses, Genetic; Female; Heart Rate; Hypertension; Male; Mice; Orchiectomy; Ovariectomy; Sex Characteristics; X Chromosome; Y Chromosome | 2010 |
Biomechanics and vasoreactivity of female intramural coronaries in angiotensin II induced hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Biomechanical Phenomena; Capillary Resistance; Coronary Vessels; Female; Hypertension; Models, Biological; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane A2, Prostaglandin H2; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Hypertensive effects of central angiotensin II infusion and restraint stress are reduced with age.
Topics: Aging; Angiotensin II; Animals; Base Sequence; Blood Pressure; DNA Primers; Electron Spin Resonance Spectroscopy; Heart Rate; Hypertension; Immobilization; Locomotion; Male; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological | 2010 |
Antihypertensive effect of Eucommia ulmoides Oliv. extracts in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Eucommiaceae; Hypertension; Iridoids; Male; Mesenteric Arteries; Nitric Oxide; Phytotherapy; Plant Bark; Plant Extracts; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renin; Vasodilation | 2010 |
Simultaneous administration of Ang(1-7) or A-779 does not affect the chronic hypertensive effects of angiotensin II in normal rats.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Heart Rate; Hypertension; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2010 |
Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Green Fluorescent Proteins; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; Thrombotic Microangiopathies | 2010 |
Hypertension, obesity, and inflammation: the complex designs of a deadly trio.
Topics: Adaptive Immunity; Angiotensin II; Atherosclerosis; Genes, ras; Humans; Hypertension; Inflammation; Insulin Resistance; Metabolic Syndrome; Obesity; Oxidative Stress | 2010 |
Economic evaluation of four angiotensin II receptor blockers in the treatment of hypertension.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cost Savings; Cost-Benefit Analysis; Female; Humans; Hypertension; Insurance Claim Review; Male; Managed Care Programs; Medical Audit; Middle Aged; United States; Vasoconstrictor Agents | 2010 |
Sitagliptin augments angiotensin II-induced renal vasoconstriction in kidneys from rats with metabolic syndrome.
Topics: Angiotensin II; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dipeptidyl-Peptidase IV Inhibitors; Glycated Hemoglobin; Hypertension; Kidney; Male; Metabolic Syndrome; Proteinuria; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Sitagliptin Phosphate; Triazoles; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Accelerated senescence of endothelial progenitor cells in hypertension is related to the reduction of calcitonin gene-related peptide.
Topics: Adult; Adult Stem Cells; Angiotensin II; Animals; Base Sequence; Calcitonin Gene-Related Peptide; Capsaicin; Cellular Senescence; DNA Primers; Endothelial Cells; Female; Humans; Hypertension; In Vitro Techniques; Indole Alkaloids; Male; Middle Aged; Quinazolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; TRPV Cation Channels | 2010 |
Regression of glomerulosclerosis in response to transient treatment with angiotensin II blockers is attenuated by blockade of matrix metalloproteinase-2.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hypertension; Kidney; Kidney Diseases; Kidney Glomerulus; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Random Allocation; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles; Time Factors | 2010 |
Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Genes; Heart; Humans; Hypertension; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Resveratrol; Stilbenes | 2010 |
Brain renin-angiotensin system modifies the blood pressure response to intracerebroventricular cadmium in rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Cadmium; Captopril; Clonidine; Enalapril; Heart; Histocytochemistry; Hypertension; Kallikrein-Kinin System; Kallikreins; Kidney; Male; Rats; Rats, Wistar; Renin-Angiotensin System; Saralasin | 2010 |
Increased dietary NaCl potentiates the effects of elevated prorenin levels on blood pressure and organ disease.
Topics: Angiotensin II; Angiotensins; Animals; Blood Pressure; Cardiomegaly; Chymosin; Enzyme Precursors; Fibrosis; Hypertension; Kidney Diseases; Male; Random Allocation; Rats; Rats, Transgenic; Renin; Retrospective Studies; Sodium Chloride, Dietary | 2010 |
Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Chemokine CCL2; Collagen; Fibroblasts; Fibrosis; Hypertension; Lung Diseases, Interstitial; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents | 2010 |
Antihypertensive activity of Salvia elegans Vahl. (Lamiaceae): ACE inhibition and angiotensin II antagonism.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Chromatography, Thin Layer; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Injections, Intravenous; Kinetics; Lisinopril; Losartan; Mice; Mice, Inbred ICR; Peptidyl-Dipeptidase A; Plant Components, Aerial; Plant Extracts; Salvia; Spectrophotometry, Ultraviolet | 2010 |
Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Arteries; Captopril; Chymases; Drug Stability; Hypertension; In Vitro Techniques; Male; Oligopeptides; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Mechanisms underlying off-target effects of the cholesteryl ester transfer protein inhibitor torcetrapib involve L-type calcium channels.
Topics: Adrenal Cortex; Adrenal Gland Neoplasms; Aldosterone; Amides; Angiotensin II; Animals; Anticholesteremic Agents; Blood Pressure; Calcium; Calcium Channels, L-Type; Cell Line, Tumor; Cholesterol Ester Transfer Proteins; Cytochrome P-450 CYP11B2; Cytosol; Enzyme Induction; Esters; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Gene Expression Profiling; Humans; Hypertension; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Quinolines; Rats; Rats, Inbred SHR; RNA, Small Interfering; Sodium Channels; Structure-Activity Relationship; Sulfhydryl Compounds | 2010 |
Losartan inhibits LPS-induced inflammatory signaling through a PPARgamma-dependent mechanism in human THP-1 macrophages.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Atherosclerosis; Cell Line; Gene Expression; Humans; Hypertension; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Losartan; Macrophages; Monocytes; Phosphorylation; PPAR gamma; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Signal Transduction | 2010 |
Long-term effects of telmisartan on blood pressure, the renin-angiotensin-aldosterone system, and lipids in hypertensive patients.
Topics: Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atrial Natriuretic Factor; Benzimidazoles; Benzoates; Biomarkers; Blood Pressure; Cholesterol; Drug Administration Schedule; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Peptidyl-Dipeptidase A; Prospective Studies; Renin; Renin-Angiotensin System; Telmisartan; Time Factors; Treatment Outcome; Triglycerides | 2010 |
Angiotensin II type 1a-deficient bone marrow-derived dendritic cells produce higher levels of monocyte chemoattractant protein 1.
Topics: Angiotensin II; Animals; Bone Marrow; Chemokine CCL2; Dendritic Cells; Disease Models, Animal; Glomerulonephritis; Hypertension; Immunity, Cellular; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1 | 2010 |
Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase-ROS-CTGF pathway.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cell Proliferation; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Fibroblasts; Fibrosis; Hypertension; Male; Malondialdehyde; Myocardium; NADPH Oxidases; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors; Trimetazidine; Vasodilator Agents | 2010 |
Involvement of angiotensin II in the remodeling induced by a chronic decrease in blood flow in rat mesenteric resistance arteries.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Chronic Disease; Extracellular Signal-Regulated MAP Kinases; Hypertension; Mesenteric Arteries; Mice; Mice, Knockout; Nitric Oxide Synthase Type III; Perindopril; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Intracellular or extracellular heat shock protein 70 differentially regulates cardiac remodelling in pressure overload mice.
Topics: Angiotensin II; Animals; Antibodies; Benzhydryl Compounds; Blood Pressure; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibrosis; HSP70 Heat-Shock Proteins; Hypertension; Male; Mice; Mice, Inbred ICR; Myocardium; p38 Mitogen-Activated Protein Kinases; Protein Transport; Pyrrolidinones; Signal Transduction; Time Factors; Toll-Like Receptor 4; Transcription, Genetic; Transforming Growth Factor beta1; Ventricular Remodeling | 2010 |
Antihypertensive effect of salt-free soy sauce, a new fermented seasoning, in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Hypertension; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Potassium; Random Allocation; Rats; Rats, Inbred SHR; Sodium; Sodium Chloride, Dietary; Soy Foods; Vasoconstriction | 2010 |
Nitro-oleic acid inhibits angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Linoleic Acids; Mice; Mice, Inbred C57BL; Nitro Compounds; Oleic Acid; Oleic Acids; Rats; Rats, Sprague-Dawley | 2010 |
Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension.
Topics: Administration, Oral; Adoptive Transfer; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Genes, T-Cell Receptor alpha; Genes, T-Cell Receptor beta; Homeodomain Proteins; Hydralazine; Hypertension; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Norepinephrine; Receptors, Antigen, T-Cell, alpha-beta; Superoxides; T-Lymphocytes; Third Ventricle; Time Factors; Vasculitis | 2010 |
[Effect of Jimaitong tablet combined with nifedipine on blood-pressure and mechanisms investigation in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Heart Rate; Hypertension; Male; Malondialdehyde; Nifedipine; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Superoxide Dismutase; Tablets | 2010 |
Bilirubin exerts renoprotective effects in angiotensin II-hypertension.
Topics: Angiotensin II; Animals; Bilirubin; Blood Pressure; Body Weight; Drinking; Eating; Hypertension; Male; Proteinuria; Rats; Rats, Sprague-Dawley | 2010 |
[Suppression of renin-angiotensin system and cancer therapy (discussion)].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Cimetidine; Cyclooxygenase 2 Inhibitors; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Gemcitabine; Humans; Hypertension; Interferon-alpha; Life Style; Neoplasms; Oxonic Acid; Renin-Angiotensin System; Tegafur; Tetrazoles | 2010 |
Angiotensin-converting enzyme 2 autoantibodies: further evidence for a role of the renin-angiotensin system in inflammation.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Autoantibodies; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Scleroderma, Systemic | 2010 |
Acute intravenous injection and short-term oral administration of N(G) -nitro-L-arginine methyl ester to the rat provoke increased pressor responses to agonists and hypertension, but not inhibition of acetylcholine-induced hypotensive responses.
Topics: Acetylcholine; Administration, Oral; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Hypotension; In Vitro Techniques; Injections, Intravenous; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 2011 |
An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT(1) angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Drug Design; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Receptors, Drug; Structure-Activity Relationship | 2010 |
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Endothelium, Vascular; Hydrogen Peroxide; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Up-Regulation; Vasodilation | 2010 |
Inflammation and neurogenic hypertension: a new role for the circumventricular organs?
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Lymphocyte Activation; Mice; Norepinephrine; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes; Third Ventricle; Vasculitis | 2010 |
Renal autoregulation and passive pressure-flow relationships in diabetes and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Female; Homeostasis; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; Nephrons; Papaverine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renin; Streptozocin; Vasodilator Agents | 2010 |
Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats.
Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Down-Regulation; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fumarates; Hypertension; Kidney; Losartan; Male; Mice; Pilot Projects; Radioimmunoassay; Rats; Rats, Transgenic; Renin; Time Factors | 2010 |
Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats.
Topics: Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fumarates; Heart Rate; Hypertension; Kidney Glomerulus; Losartan; Male; Proteinuria; Rats; Rats, Transgenic; Renin; Time Factors | 2010 |
Moderate hyperbilirubinemia improves renal hemodynamics in ANG II-dependent hypertension.
Topics: Angiotensin II; Animals; Bilirubin; Blotting, Western; Glomerular Filtration Rate; Glucuronosyltransferase; Hyperbilirubinemia; Hypertension; Indinavir; Liver; Male; Mice; Mice, Inbred C57BL; Morpholines; Oligonucleotides, Antisense; Organic Cation Transport Proteins; Protein Synthesis Inhibitors; Renal Circulation | 2010 |
The counter-regulatory effects of ESE-1 during angiotensin II-mediated vascular inflammation and remodeling.
Topics: Angiotensin II; Animals; Aorta; DNA-Binding Proteins; Endothelium, Vascular; Humans; Hypertension; Male; Mice; Mice, Knockout; Nitric Oxide Synthase Type II; Transcription Factors; Vasculitis | 2010 |
Adenoviral inhibition of AT1a receptors in the paraventricular nucleus inhibits acute increases in mean arterial blood pressure in the rat.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Transfer Techniques; Genetic Vectors; Heart Rate; Hypertension; Male; Microinjections; Muscle, Smooth, Vascular; Paraventricular Hypothalamic Nucleus; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering; Telemetry; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2010 |
High salt intake delayed angiotensin II-induced hypertension in mice with a genetic variant of NADPH oxidase.
Topics: Angiotensin II; Animals; Hypertension; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Sodium; Sodium Chloride, Dietary; Superoxides; Systole; Urination | 2011 |
Angiotensin (1-7) receptor antagonism equalizes angiotensin II-induced hypertension in male and female spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Female; Hypertension; Kidney Cortex; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sex Factors; Vasoconstrictor Agents | 2010 |
Hypertension induced by angiotensin II and a high salt diet involves reduced SK current and increased excitability of RVLM projecting PVN neurons.
Topics: Action Potentials; Analysis of Variance; Angiotensin II; Animals; Apamin; Hypertension; Male; Membrane Potentials; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2010 |
Salt-induced cardiac hypertrophy and interstitial fibrosis are due to a blood pressure-independent mechanism in Wistar rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Collagen Type I; Collagen Type III; Disease Models, Animal; Drinking; Eating; Echocardiography; Fibrosis; Gene Expression; Heart Ventricles; Hydralazine; Hypertension; Losartan; Male; Myocardium; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Transforming Growth Factor beta; Urine | 2010 |
Contrasting effects of intervention with ETA and ETB receptor antagonists in hypertension induced by angiotensin II and high-salt diet.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Hypertension; Male; Nitrates; Nitrites; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Treatment Outcome | 2010 |
HO-1 attenuates hypertension-induced inflammation/oxidative stress: support from Bartter's/Gitelman's patients.
Topics: Aldosterone; Angiotensin II; Bartter Syndrome; Blood Pressure; Heme Oxygenase-1; Humans; Hypertension; Inflammation; Oxidative Stress; Renin-Angiotensin System; Vascular Resistance | 2010 |
MicroRNA-155 regulates angiotensin II type 1 receptor expression and phenotypic differentiation in vascular adventitial fibroblasts.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cell Differentiation; Cells, Cultured; Down-Regulation; Fibroblasts; Gene Expression Regulation; Hypertension; Luciferases; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2010 |
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chronic Disease; Desoxycorticosterone; Disease Models, Animal; Disease Progression; Fibrosis; Genetic Predisposition to Disease; Glomerulonephritis; Heart Diseases; Hydralazine; Hypertension; Imidazoles; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Kidney Diseases; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Nephrectomy; Sodium Chloride, Dietary; Species Specificity; Telemetry; Tetrazoles; Time Factors; X-Ray Microtomography | 2010 |
The renin-angiotensin system and hypertension in autosomal recessive polycystic kidney disease.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Hypertension; Kidney; Male; Mutation; Peptidyl-Dipeptidase A; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Time Factors | 2010 |
Cytochrome P450 1B1 contributes to angiotensin II-induced hypertension and associated pathophysiology.
Topics: Angiotensin II; Animals; Aorta; Aryl Hydrocarbon Hydroxylases; Blood Pressure; Blotting, Western; Cardiomegaly; Cytochrome P-450 CYP1B1; Endothelium, Vascular; Hypertension; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardium; NADPH Oxidases; Organ Size; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stilbenes; Vasoconstrictor Agents | 2010 |
Gene expression profiles linked to AT1 angiotensin receptors in the kidney.
Topics: Angiotensin II; Animals; Cluster Analysis; Female; Gene Expression; Gene Expression Profiling; Gene Regulatory Networks; Hypertension; Immediate-Early Proteins; Immunoblotting; Infusions, Subcutaneous; Kidney; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Vasoconstrictor Agents | 2010 |
Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure.
Topics: Angiotensin II; Angiotensinogen; Animals; bcl-2-Associated X Protein; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Heart; Heart Failure; Heart Rate; Humans; Hydrazones; Hypertension; Major Histocompatibility Complex; Male; Pyridazines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Simendan | 2010 |
Losartan attenuates vascular remodeling of the aorta in spontaneously hypertensive rats and the underlying mechanism.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Catalase; Hydrogen Peroxide; Hypertension; Losartan; Male; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2010 |
Cardiac angiotensin II: does it have a function?
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart; Hypertension; Mice; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Ventricular Remodeling | 2010 |
Local angiotensin II aggravates cardiac remodeling in hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Collagen; Desoxycorticosterone; Dinoprost; Disease Models, Animal; Heart Rate; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, Transgenic; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2010 |
Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension.
Topics: Adiponectin; Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Genetic Therapy; Genetic Vectors; HEK293 Cells; Heme Oxygenase-1; Humans; Hypertension; Inflammation; Kidney; Lentivirus; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Vasodilation | 2011 |
CYP4A2-induced hypertension is 20-hydroxyeicosatetraenoic acid- and angiotensin II-dependent.
Topics: Amidines; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blotting, Western; Cells, Cultured; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Hydroxyeicosatetraenoic Acids; Hypertension; Lentivirus; Lisinopril; Losartan; Mass Spectrometry; Oligonucleotide Array Sequence Analysis; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2010 |
Number and function of circulating endothelial progenitor cells and calcitonin gene-related peptide in hypertension: support from and opportunities in Bartter's and Gitelman's syndromes patients.
Topics: Angiotensin II; Bartter Syndrome; Blood Pressure; Calcitonin Gene-Related Peptide; Cellular Senescence; Endothelium, Vascular; Gitelman Syndrome; Heme Oxygenase-1; Humans; Hypertension; Oxidative Stress; Stem Cells | 2010 |
Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy.
Topics: Age Factors; Aging; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomyopathies; Collagen; Coronary Circulation; Disease Models, Animal; Echocardiography; Elasticity; Enzyme Inhibitors; Extracellular Matrix; Female; Gene Expression Profiling; Gene Expression Regulation; Genotype; Heart Ventricles; Hemodynamics; Hypertension; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Microscopy, Electron; Microscopy, Video; Myocardium; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenotype; Polymerase Chain Reaction; RNA, Messenger; Telemetry; Ventricular Remodeling | 2010 |
Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Proliferation; Cells, Cultured; CSK Tyrosine-Protein Kinase; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Free Radical Scavengers; Hyperplasia; Hypertension; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; src-Family Kinases; Superoxides | 2010 |
Role of the organum vasculosum of the lamina terminalis for the chronic cardiovascular effects produced by endogenous and exogenous ANG II in conscious rats.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Heart Rate; Hypertension; Hypotension; Hypothalamus; Losartan; Male; Rats; Rats, Sprague-Dawley; Telemetry | 2010 |
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Creatinine; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Furosemide; Hydrochlorothiazide; Hypertension; Indoles; Kidney Failure, Chronic; Labetalol; Losartan; Proteinuria; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System | 2010 |
The contribution of α1B-adrenoceptor subtype in the renal vasculature of fructose-fed Sprague-Dawley rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Animals; Dietary Carbohydrates; Dose-Response Relationship, Drug; Fructose; Hemodynamics; Hyperglycemia; Hyperinsulinism; Hypertension; Kidney; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Does interleukin 6 contribute to renal hemodynamic changes during angiotensin II-dependent hypertension?
Topics: Angiotensin II; Hemodynamics; Humans; Hypertension; Interleukin-6 | 2010 |
Interleukin 6 knockout prevents angiotensin II hypertension: role of renal vasoconstriction and janus kinase 2/signal transducer and activator of transcription 3 activation.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Dose-Response Relationship, Drug; Hypertension; Immunoenzyme Techniques; Interleukin-6; Janus Kinase 2; Kidney; Mice; Mice, Knockout; Phosphorylation; Random Allocation; Renal Circulation; Signal Transduction; STAT3 Transcription Factor; Vasoconstriction | 2010 |
Angiotensin II-induced hypertension enhanced therapeutic efficacy of liposomal doxorubicin in tumor-bearing mice.
Topics: Angiotensin II; Animals; Antibiotics, Antineoplastic; Blood Circulation; Carcinoma, Lewis Lung; Colonic Neoplasms; Doxorubicin; Female; Hypertension; Injections, Intravenous; Liposomes; Mice; Mice, Inbred Strains; Tissue Distribution | 2011 |
The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Cerebrovascular Circulation; Electrophysiology; Evoked Potentials; Hypertension; Immunohistochemistry; Infusion Pumps; Laser-Doppler Flowmetry; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Telemetry; Time Factors; Vasoconstrictor Agents; Vibrissae | 2011 |
A novel atrial natriuretic peptide based therapeutic in experimental angiotensin II mediated acute hypertension.
Topics: Acute Disease; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Diuresis; Dogs; Glomerular Filtration Rate; Humans; Hypertension; Male; Natriuresis; Pulmonary Wedge Pressure; Renal Circulation; Vascular Resistance | 2010 |
Is the deficiency of the long isoform of cellular FLICE-inhibitory protein involved in myocardial remodeling?
Topics: Angiotensin II; Animals; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 10; Humans; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Myocytes, Cardiac; Protein Isoforms; Ventricular Remodeling | 2010 |
Angiotensin II-mediated microvascular thrombosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bradykinin Receptor Antagonists; Endothelin Receptor Antagonists; Hypertension; Male; Mice; Mice, Inbred C57BL; Microvessels; Platelet Aggregation; Receptors, Angiotensin; Receptors, Bradykinin; Receptors, Endothelin; Thrombosis | 2010 |
Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sleep Apnea Syndromes | 2011 |
Mechanisms underlying the cerebral microvascular responses to angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Cell Adhesion; Cerebrovascular Circulation; Chemokine CCL5; Homeodomain Proteins; Hypertension; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Video; Microvessels; P-Selectin; Platelet Adhesiveness; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; T-Lymphocytes; Transplantation Chimera | 2010 |
Amlodipine suppressed cardiac gene expression of brain natriuretic peptide, transforming growth factor-β₁ and fibronectin mediated by aldosterone in male stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Fibronectins; Gene Expression Regulation; Heart; Hypertension; Male; Myocardium; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Transforming Growth Factor beta | 2010 |
Influences of aortic motion and curvature on vessel expansion in murine experimental aneurysms.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomechanical Phenomena; Blood Pressure; Disease Progression; Elastin; Hypertension; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Models, Cardiovascular; Ultrasonography | 2011 |
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acids; Benzoates; Blood Pressure; Cytochrome P-450 CYP1A1; Disease Models, Animal; Enzyme Inhibitors; Epoxide Hydrolases; Glomerular Filtration Rate; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mice; Promoter Regions, Genetic; Proteinuria; Rats; Renal Plasma Flow; Renin; Sodium; Time Factors; Urea | 2011 |
MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Cardiomegaly; Fibrosis; Gene Expression Regulation, Enzymologic; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 7; Mice; Mice, Inbred C57BL; Myocardium; Rats; Rats, Sprague-Dawley; RNA Interference; Transcription, Genetic; Up-Regulation | 2011 |
Supramolecular interactions between losartan and hydroxypropyl-β-CD: ESI mass-spectrometry, NMR techniques, phase solubility, isothermal titration calorimetry and anti-hypertensive studies.
Topics: Administration, Oral; alpha-Cyclodextrins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Calorimetry; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Carriers; Drug Compounding; Hypertension; Kinetics; Losartan; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Solubility; Spectrometry, Mass, Electrospray Ionization; Technology, Pharmaceutical | 2011 |
The frail renin-angiotensin system.
Topics: Aged; Aging; Angiotensin II; Apoptosis; Disease Progression; Frail Elderly; Humans; Hypertension; Inflammation; Oxidative Stress; Reactive Oxygen Species; Receptors, Angiotensin; Renin-Angiotensin System | 2011 |
Hemodynamic responses to aortic depressor nerve stimulation in conscious L-NAME-induced hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Atenolol; Atropine Derivatives; Baroreflex; Blood Pressure; Electric Stimulation; Heart Rate; Hemodynamics; Hypertension; Male; NG-Nitroarginine Methyl Ester; Parasympatholytics; Prazosin; Rats; Rats, Wistar | 2011 |
Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Heart Rate; Hexamethonium; Hypertension; Immunohistochemistry; Infusion Pumps, Implantable; Infusions, Intraventricular; Mineralocorticoid Receptor Antagonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; RNA, Small Interfering; Sympathetic Nervous System; Telemetry | 2011 |
Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Female; Hypertension; Infusions, Subcutaneous; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1 | 2011 |
Vitamin D and the vascular sensitivity to angiotensin II in obese Caucasians with hypertension.
Topics: Angiotensin II; Biomarkers; Blood Pressure; Chi-Square Distribution; Female; France; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Obesity; Renin; Renin-Angiotensin System; Retrospective Studies; Risk Assessment; Risk Factors; United States; Vitamin D; Vitamin D Deficiency; White People | 2011 |
Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension.
Topics: Abatacept; Angiotensin II; Animals; Antihypertensive Agents; B7-1 Antigen; B7-2 Antigen; CD28 Antigens; Cells, Cultured; Gene Deletion; Hypertension; Immunoconjugates; Immunosuppressive Agents; Ligands; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Random Allocation; T-Lymphocytes | 2010 |
Underuse of ACE inhibitors and angiotensin II receptor blockers among patients with diabetic nephropathy in Taiwan.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cohort Studies; Databases as Topic; Diabetic Nephropathies; Disease Progression; Female; Guideline Adherence; Humans; Hypertension; Male; Middle Aged; Practice Patterns, Physicians'; Proteinuria; Taiwan; Vasoconstrictor Agents | 2011 |
Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biopterins; Cyclic GMP; GTP Cyclohydrolase; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reserpine; Signal Transduction | 2011 |
Blockade of AT1 receptors protects the blood-brain barrier and improves cognition in Dahl salt-sensitive hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood-Brain Barrier; Body Weight; Capillary Permeability; Cognition; Corpus Callosum; Hippocampus; Hypertension; Imidazoles; Immunohistochemistry; Male; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Inbred Dahl; RNA, Messenger; Systole; Tetrazoles | 2011 |
Mitogen-activated protein kinase-activated protein kinase 2 in angiotensin II-induced inflammation and hypertension: regulation of oxidative stress.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blotting, Western; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Hypertension; Inflammation; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NADPH Oxidases; NF-kappa B; Oxidative Stress; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Superoxides; Vascular Cell Adhesion Molecule-1 | 2011 |
[Change of mitogen-activated protein kinase phosphatase-1 in heart and aorta of SHR and its effect on proliferation of vascular smooth muscle cells stimulated by angiotensin II].
Topics: Angiotensin II; Animals; Aorta; Cell Proliferation; Cells, Cultured; Dual Specificity Phosphatase 1; Heart; Hypertension; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocardium; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2002 |
Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. AT1 receptors in the kidney mediate the chronic hypertensive
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Kidney; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sympathetic Nervous System; Treatment Outcome | 2010 |
Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Intrarenal angiotensin II generation as a hypertensinogenic
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Kidney; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System | 2010 |
Lack of microsomal prostaglandin E synthase-1 reduces cardiac function following angiotensin II infusion.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cardiomegaly; Echocardiography; Hypertension; Intramolecular Oxidoreductases; Mice; Mice, Inbred C57BL; Mice, Knockout; Microsomes; Myocytes, Cardiac; Prostaglandin-E Synthases; Ventricular Function | 2011 |
Nitric oxide modulates reactivity to angiotensin II in internal mammary arterial grafts in hypertensive patients without associated risk factors.
Topics: Aged; Angiotensin II; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Hypertension; Male; Mammary Arteries; Membrane Potentials; Middle Aged; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitrites; Oxidative Stress; Vasoconstriction | 2011 |
1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.
Topics: Adamantane; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Disease Models, Animal; Enzyme Inhibitors; Epoxide Hydrolases; Hypertension; Insulin Resistance; Mice; Obesity; Rats; Urea | 2011 |
[Effects of Bai-Chuan capsule on left ventricular hypertrophy and correlative indexes].
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Apiaceae; Blood Pressure; Capsules; Captopril; Drugs, Chinese Herbal; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Radioimmunoassay; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2010 |
Tetrahydrobiopterin and hypertension: more than an emigrating story.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biopterins; Drug Therapy, Combination; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Reserpine; Signal Transduction | 2011 |
Angiotensin II type 1A receptors in vascular smooth muscle cells do not influence aortic remodeling in hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Receptor, Angiotensin, Type 1; Vasoconstriction; Vasoconstrictor Agents | 2011 |
TRPC6 enhances angiotensin II-induced albuminuria.
Topics: Albuminuria; Angiotensin II; Animals; Calcium; Disease Models, Animal; Hypertension; Injections, Subcutaneous; Kidney; Male; Mice; Mice, Knockout; Patch-Clamp Techniques; Podocytes; TRPC Cation Channels; TRPC6 Cation Channel | 2011 |
T regulatory lymphocytes prevent angiotensin II-induced hypertension and vascular injury.
Topics: Acetylcholine; Adaptive Immunity; Analysis of Variance; Angiotensin II; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Flow Cytometry; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory; Vascular Cell Adhesion Molecule-1; Vasodilator Agents | 2011 |
IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Blotting, Western; Bone Marrow Transplantation; Cardiomegaly; Cell Proliferation; Cells, Cultured; DNA, Complementary; Echocardiography; Fibrosis; Gene Expression Profiling; Hypertension; Immunity, Innate; Interferon Regulatory Factor-3; Leukocyte Common Antigens; Mice; Mice, Inbred ICR; Mice, Knockout; Proto-Oncogene Proteins c-bcl-2; Ventricular Remodeling | 2011 |
Renal injury in angiotensin II+L-NAME-induced hypertensive rats is independent of elevated blood pressure.
Topics: Acute Kidney Injury; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Kidney; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 2011 |
Angiotensin II stimulates renin in inner medullary collecting duct cells via protein kinase C and independent of epithelial sodium channel and mineralocorticoid receptor activity.
Topics: Analysis of Variance; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Epithelial Sodium Channels; Fluorescent Antibody Technique; Hypertension; Kidney Medulla; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2011 |
Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Blotting, Western; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Dose-Response Relationship, Drug; Hypertension; Male; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Vasoconstriction; Vinca Alkaloids | 2011 |
Involvement of vascular peroxidase 1 in angiotensin II-induced vascular smooth muscle cell proliferation.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix Proteins; Free Radical Scavengers; Hydrogen Peroxide; Hypertension; Hypochlorous Acid; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Peroxidase; Peroxidasin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors | 2011 |
HNF4alpha dysfunction as a molecular rational for cyclosporine induced hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Computational Biology; Consensus Sequence; Cyclosporine; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Humans; Hypertension; Immunosuppressive Agents; NFATC Transcription Factors; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Transcription, Genetic | 2011 |
Intrarenal transfer of an intracellular fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Hypertension; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Natriuresis; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Time Factors; Transduction, Genetic; Transfection; Up-Regulation; Urination | 2011 |
Pivotal role of protein kinase Cdelta in angiotensin II-induced endothelial cyclooxygenase-2 expression: a link to vascular inflammation.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Blotting, Western; Cells, Cultured; Chemokine CCL2; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Inflammation; Inflammation Mediators; Male; Mesenteric Arteries; Middle Aged; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; RNA Interference; Signal Transduction; Time Factors; Tissue Culture Techniques; Up-Regulation | 2011 |
Soluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin II-dependent hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Body Weight; Hypertension; Immunohistochemistry; Infusion Pumps, Implantable; Kidney; Male; Prorenin Receptor; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Renin; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
P2X1 receptor-mediated vasoconstriction of afferent arterioles in angiotensin II-infused hypertensive rats fed a high-salt diet.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Blotting, Western; Homeostasis; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X1; Renal Circulation; Sodium, Dietary; Vasoconstriction | 2011 |
Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Brain; Captopril; Cytokines; Heart; Hydralazine; Hypertension; In Vitro Techniques; Insulin; Kidney; Leptin; Male; Myocardial Contraction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Proteinuria; Rats; Rats, Inbred SHR; Ventricular Function, Left | 2011 |
Renin angiotensin system and cardiac hypertrophy after sinoaortic denervation in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carotid Sinus; Collagen; Denervation; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Renin-Angiotensin System | 2010 |
Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Hydrogen Peroxide; Hypertension; Janus Kinase 2; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; rho-Associated Kinases; Time Factors; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2011 |
Role of intrarenal angiotensin system activation, oxidative stress, inflammation, and impaired nuclear factor-erythroid-2-related factor 2 activity in the progression of focal glomerulosclerosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Progression; Glomerulosclerosis, Focal Segmental; Hypertension; Imidazoles; Kidney; Kidney Diseases; Male; NF-E2 Transcription Factor; NF-kappa B; Oxidative Stress; Proteinuria; Random Allocation; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Tetrazoles; Thiobarbituric Acid Reactive Substances | 2011 |
Influence of angiotensin-converting enzyme insertion/deletion polymorphism on nitric oxide production in hypertensives and hypercholesterolaemics.
Topics: Adult; Alleles; Angiotensin II; Arginine; Base Sequence; Blood Pressure; China; Female; Gene Deletion; Genotype; Humans; Hypercholesterolemia; Hypertension; INDEL Mutation; Male; Nitric Oxide; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Vasodilation | 2011 |
Trapping intracellular ANG II to the proximal tubule: powerful in vivo effects on sodium handling and blood pressure.
Topics: Adenoviridae; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Hypertension; Kidney Tubules, Proximal; Mice; Natriuresis; Rats; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Transduction, Genetic; Up-Regulation; Urination | 2011 |
Contribution of renal purinergic receptors to renal vasoconstriction in angiotensin II-induced hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Arterioles; Blood Pressure; Blotting, Western; Glomerular Filtration Rate; Hemodynamics; Hypertension; Immunohistochemistry; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Receptors, Purinergic P2X1; Receptors, Purinergic P2Y1; Renal Circulation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstriction | 2011 |
Evidence for the role of α1A-adrenoceptor subtype in the control of renal haemodynamics in fructose-fed Sprague-Dawley rat.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Animals; Fructose; Hemodynamics; Hypertension; Kidney; Kidney Diseases; Male; Methoxamine; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Effect of myricetin on deoxycorticosterone acetate (DOCA)-salt-hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Catalase; Desoxycorticosterone; Disease Models, Animal; Female; Flavonoids; Glutathione; Heart Rate; Hypertension; Oxidative Stress; Rats; Rats, Wistar; Serotonin; Sodium Chloride; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitaceae | 2011 |
Chronic angiotensin II infusion modulates angiotensin II type I receptor expression in the subfornical organ and the rostral ventrolateral medulla in hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Gene Expression Regulation; Hypertension; Losartan; Male; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Subfornical Organ; Sympathetic Nervous System | 2011 |
Ang II Upregulation of the T-lymphocyte renin-angiotensin system is amplified by low-grade inflammation in human hypertension.
Topics: Aged; Angiotensin II; C-Reactive Protein; Female; Humans; Hypertension; Inflammation; Male; Middle Aged; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; T-Lymphocytes; Up-Regulation | 2011 |
[Effect of irbesartan of the function of hemocoagulative component of hemostasis in patients with arterial hypertension during metabolic syndrome].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Female; Follow-Up Studies; Hemostasis; Humans; Hypertension; Irbesartan; Male; Metabolic Syndrome; Middle Aged; Tetrazoles; Treatment Outcome | 2010 |
[Prevention of hypertension by drugs and immunization against angiotensin II].
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Tetrazoles; Vaccines | 2011 |
Histone acetylation is essential for ANG-II-induced IGF-IIR gene expression in H9c2 cardiomyoblast cells and pathologically hypertensive rat heart.
Topics: Acetylation; Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; Gene Expression; Histones; Hypertension; Myoblasts; Myocardium; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Receptor, IGF Type 2; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation; Ventricular Remodeling | 2012 |
Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats.
Topics: Achillea; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Flavonoids; Hypertension; Male; Methylene Chloride; Oils, Volatile; Peptidyl-Dipeptidase A; Phytotherapy; Plant Extracts; Rats; Rats, Wistar | 2011 |
MG132 treatment attenuates cardiac remodeling and dysfunction following aortic banding in rats via the NF-κB/TGFβ1 pathway.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Collagen; Constriction; Fibrosis; Hemodynamics; Hypertension; Leupeptins; Male; Myocardium; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Transforming Growth Factor beta1; Ubiquitin; Ultrasonography; Ventricular Remodeling | 2011 |
Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinases.
Topics: Angiotensin II; Animals; Arterioles; Disease Models, Animal; Hypertension; Male; Matrix Metalloproteinases; Norepinephrine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Resistance; Vasoconstriction | 2011 |
Effect of pregnancy and diabetes on vascular receptors for angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes, Gestational; Disease Models, Animal; Endothelium, Vascular; Female; Hypertension; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Risk Factors; Streptozocin; Vasoconstriction | 2011 |
AT1 receptor antagonist candesartan attenuates genomic damage in peripheral blood lymphocytes of patients on maintenance hemodialysis treatment.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Antimutagenic Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Nucleus; Cell Separation; Female; Glycation End Products, Advanced; Humans; Hypertension; Kidney Failure, Chronic; Kidney Function Tests; Lymphocytes; Male; Micronucleus Tests; Middle Aged; Renal Dialysis; Tetrazoles | 2011 |
Changes in plasma angiotensin II and circadian rhythm of blood pressure in hypertensive patients with sleep apnea syndrome before and after treatment.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Continuous Positive Airway Pressure; Female; Humans; Hypertension; Male; Middle Aged; Pharynx; Polysomnography; Sleep Apnea Syndromes | 2011 |
Exacerbation of thrombotic events by diesel exhaust particle in mouse model of hypertension.
Topics: Air Pollutants; Angiotensin II; Animals; Blood Platelets; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Mice; Oxygen; Partial Thromboplastin Time; Particulate Matter; Platelet Aggregation; Prothrombin Time; Thrombosis; Vehicle Emissions | 2011 |
New take on the role of angiotensin II in cardiac hypertrophy and fibrosis.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Fibrosis; Humans; Hypertension; Inflammation; Mice; Myocardium; Oxidative Stress; Receptor, Angiotensin, Type 1; Sodium; Ventricular Remodeling | 2011 |
Vascular peroxidase 1/peroxidasin: a complex protein with a simple function?
Topics: Angiotensin II; Animals; Cell Proliferation; Extracellular Matrix Proteins; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peroxidase; Peroxidasin | 2011 |
Notch3 is essential for regulation of the renal vascular tone.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Bradykinin; Epoprostenol; Gene Expression; Humans; Hypertension; Immunohistochemistry; In Vitro Techniques; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Receptor, Notch3; Receptors, Notch; Renal Circulation; Reverse Transcriptase Polymerase Chain Reaction; Skin; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Endothelial Cells; Hypertension; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidases; Reactive Oxygen Species; Superoxide Dismutase; Vasodilation | 2011 |
An ethanolic extract of Lindera obtusiloba stems causes NO-mediated endothelium-dependent relaxations in rat aortic rings and prevents angiotensin II-induced hypertension and endothelial dysfunction in rats.
Topics: Angiotensin II; Animals; Aorta; Cattle; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Ethanol; Hypertension; Lindera; Male; Medicine, East Asian Traditional; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Extracts; Plant Stems; Rats; Rats, Sprague-Dawley | 2011 |
Altered regulation of the rostral ventrolateral medulla in hypertensive obese Zucker rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain Stem; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Hypertension; Losartan; Medulla Oblongata; Microinjections; Muscle Tonus; Muscle, Smooth, Vascular; Obesity; Rats; Rats, Zucker; Receptors, GABA-A; Splanchnic Circulation; Sympathetic Nervous System | 2011 |
Intramyocardial BNP gene delivery improves cardiac function through distinct context-dependent mechanisms.
Topics: Adenoviridae; Angiotensin II; Animals; Collagen Type III; Disease Models, Animal; Fibrosis; Gene Transfer Techniques; Genetic Therapy; Humans; Hypertension; Ligation; Male; Myocardial Infarction; Natriuretic Peptide, Brain; Neovascularization, Physiologic; Organothiophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Dysfunction, Left; Ventricular Remodeling | 2011 |
Endothelial NADPH oxidases: friends or foes?
Topics: Angiotensin II; Animals; Endothelial Cells; Hypertension; Membrane Glycoproteins; Mice; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide | 2011 |
CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis.
Topics: Analysis of Variance; Angiotensin II; Animals; Biomarkers; Blood Pressure; Bone Marrow Cells; Cardiomegaly; Cell Movement; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Diseases; Heart Rate; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptors, CCR2; Stem Cells; Stroke Volume; Time Factors; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Angiotensin-converting enzyme inhibition augments the expression of rat elastase-2, an angiotensin II-forming enzyme.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Disease Models, Animal; Enalapril; Hypertension; Immunohistochemistry; Male; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; Rats, Wistar; RNA, Messenger; Serine Endopeptidases; Time Factors; Up-Regulation; Vasoconstriction | 2011 |
Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrinolysin; Fibrosis; Glomerulonephritis; Heart Diseases; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Plasminogen; Plasminogen Activator Inhibitor 1; Prevalence; Risk Factors; Tissue Plasminogen Activator | 2011 |
Altered regulation of renal nitric oxide and atrial natriuretic peptide systems in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Hypertension; Kidney; Kidney Function Tests; Male; Neprilysin; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Tyrosine | 2011 |
Angiotensin II-induced MMP-2 activity and MMP-14 and basigin protein expression are mediated via the angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium: implications for age-related macular degeneration
Topics: Angiotensin II; Animals; Basigin; Blood Pressure; Cell Line; Enzyme Activation; Gene Silencing; Hypertension; JNK Mitogen-Activated Protein Kinases; Macular Degeneration; MAP Kinase Signaling System; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptor, Angiotensin, Type 1; Renin; Retinal Pigment Epithelium; Systole; Up-Regulation | 2011 |
IκBβ attenuates angiotensin II-induced cardiovascular inflammation and fibrosis in mice.
Topics: Angiotensin II; Animals; Cells, Cultured; Cytokines; Fibrosis; Hypertension; I-kappa B Proteins; Inflammation Mediators; Mice; Mice, Knockout; Myocardium | 2011 |
Sex differences in renal medullary endothelin receptor function in angiotensin II hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Kidney Medulla; Male; Natriuresis; Rats; Receptors, Endothelin; Sex Characteristics; Viper Venoms | 2011 |
Moderate caveolin-1 downregulation prevents NADPH oxidase-dependent endothelial nitric oxide synthase uncoupling by angiotensin II in endothelial cells.
Topics: Angiotensin II; Animals; Caveolin 1; Cells, Cultured; Down-Regulation; Endothelial Cells; Hemoglobins; Humans; Hypertension; Male; Mice; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-abl; Reactive Oxygen Species; Superoxides | 2011 |
Relaxin ameliorates hypertension and increases nitric oxide metabolite excretion in angiotensin II but not N(ω)-nitro-L-arginine methyl ester hypertensive rats.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Relaxin | 2011 |
Effects of chronic dietary salt loading on the renin angiotensin and adrenergic systems of rainbow trout (Oncorhynchus mykiss).
Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Chromaffin Cells; Disease Models, Animal; Epinephrine; Female; Hypertension; Hypotension; Hypoxia; Male; Norepinephrine; Oncorhynchus mykiss; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2011 |
Phosphoproteomic analysis of AT1 receptor-mediated signaling responses in proximal tubules of angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Genes; Glycogen Synthase Kinase 3; Hypertension; Kidney Tubules, Proximal; Losartan; Male; MAP Kinase Signaling System; Mice; Phosphoproteins; Phosphorylation; Protein Kinase C-alpha; Proteomics; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers | 2011 |
Role of angiotensin-(1-7) in rostral ventrolateral medulla in blood pressure regulation via sympathetic nerve activity in Wistar-Kyoto and spontaneous hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan | 2011 |
Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR.
Topics: Acetylcysteine; Adenylyl Cyclases; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Colforsin; CSK Tyrosine-Protein Kinase; ErbB Receptors; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypertension; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; src-Family Kinases; Transcriptional Activation | 2011 |
Inflammation and hypertension: the interplay of interleukin-6, dietary sodium, and the renin-angiotensin system in humans.
Topics: Adult; Angiotensin II; C-Reactive Protein; Diet, Sodium-Restricted; Female; Humans; Hypertension; Inflammation; Interleukin-6; Male; Middle Aged; Multivariate Analysis; Renin; Renin-Angiotensin System | 2011 |
Role of vascular extracellular superoxide dismutase in hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Hydrogen Peroxide; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Nitric Oxide; Superoxide Dismutase | 2011 |
High-fructose feeding impacts on the adrenergic control of renal haemodynamics in the rat.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Dietary Carbohydrates; Fructose; Hemodynamics; Hyperglycemia; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Kidney; Male; Norepinephrine; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Angiotensin; Renal Circulation; Vasoconstrictor Agents | 2012 |
Downregulation of Kv7.4 channel activity in primary and secondary hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Carbamates; Down-Regulation; Hypertension; In Vitro Techniques; Indoles; KCNQ Potassium Channels; Male; Membrane Potentials; Mesenteric Arteries; Mice; Phenylenediamines; Rats; Rats, Inbred SHR; Rats, Wistar; Vasoconstrictor Agents | 2011 |
MicroRNA-130a mediates proliferation of vascular smooth muscle cells in hypertension.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Homeodomain Proteins; Hypertension; Male; MicroRNAs; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley | 2011 |
Aorta from angiotensin II hypertensive mice exhibit preserved nitroxyl anion mediated relaxation responses.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Hypertension; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; Nitrogen Oxides; Potassium Channel Blockers; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2012 |
MiR-133a regulates collagen 1A1: potential role of miR-133a in myocardial fibrosis in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Collagen Type I; Collagen Type I, alpha 1 Chain; Fibrosis; Gene Expression Regulation; Heart Diseases; Hypertension; Male; MicroRNAs; Rats; Rats, Sprague-Dawley | 2012 |
Antenatal nicotine induces heightened oxidative stress and vascular dysfunction in rat offspring.
Topics: Acetophenones; Angiotensin II; Animals; Aorta; Blotting, Western; Cyclic N-Oxides; Dose-Response Relationship, Drug; Female; Hypertension; Male; Malondialdehyde; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nicotine; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxide Dismutase; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Mechanisms mediating sodium-induced pressor responses in the PVN of Dahl rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Hypertension; Infusions, Intraventricular; Male; Mineralocorticoid Receptor Antagonists; Neurons; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Dahl; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Signal Transduction; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium Chloride, Dietary; Time Factors | 2011 |
Angiotensin II utilizes Janus kinase 2 in hypertension, but not in the physiological control of blood pressure, during low-salt intake.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, Sodium-Restricted; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension; Infusions, Intravenous; Janus Kinase 2; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Tyrphostins | 2011 |
Antihypertensive, insulin-sensitising and renoprotective effects of a novel, potent and long-acting angiotensin II type 1 receptor blocker, azilsartan medoxomil, in rat and dog models.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Blood Glucose; Blood Pressure; CHO Cells; Cricetinae; Cricetulus; Dogs; Hypertension; Hypertension, Renal; Imidazoles; Insulin; Male; Olmesartan Medoxomil; Oxadiazoles; Protective Agents; Proteinuria; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Tetrazoles | 2011 |
Interleukin-10 released by CD4(+)CD25(+) natural regulatory T cells improves microvascular endothelial function through inhibition of NADPH oxidase activity in hypertensive mice.
Topics: Acetylcholine; Angiotensin II; Animals; CD4 Antigens; Cell- and Tissue-Based Therapy; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Hypertension; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microvessels; NADPH Oxidases; T-Lymphocytes, Regulatory; Vasodilation; Vasodilator Agents | 2011 |
Modulation of the myogenic response in renal blood flow autoregulation by NO depends on endothelial nitric oxide synthase (eNOS), but not neuronal or inducible NOS.
Topics: Angiotensin II; Animals; Blood Pressure; Enzyme Inhibitors; Female; Homeostasis; Hypertension; Kidney; Male; Mesangial Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Renal Circulation; Vascular Resistance; Vasoconstriction | 2011 |
Cyclo-oxygenase-2 knockout genotype in mice is associated with blunted angiotensin II-induced oxidative stress and hypertension.
Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Heart; Hypertension; Kidney; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Organ Size; Oxidative Stress; Superoxides | 2011 |
Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension.
Topics: 4-Aminopyridine; Adipocytes; Adipose Tissue; Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Endothelium, Vascular; Fibroblasts; Glyburide; Hypertension; Losartan; Male; Palmitates; Peptides; Potassium Channels, Voltage-Gated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2011 |
Reciprocal roles of angiotensin II and Angiotensin II Receptors Blockade (ARB) in regulating Cbfa1/RANKL via cAMP signaling pathway: possible mechanism for hypertension-related osteoporosis and antagonistic effect of ARB on hypertension-related osteoporos
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Core Binding Factor Alpha 1 Subunit; Cyclic AMP; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Nitric Oxide; Osteoporosis; RANK Ligand; Receptor, Angiotensin, Type 2; Signal Transduction | 2011 |
Prediction of off-target effects on angiotensin-converting enzyme 2.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Chromatography, High Pressure Liquid; Diminazene; Dose-Response Relationship, Drug; Enzyme Activation; High-Throughput Screening Assays; Humans; Hypertension; Kinetics; Models, Molecular; Peptides; Peptidyl-Dipeptidase A; Prescription Drugs; Protein Binding; Small Molecule Libraries; Substrate Specificity; Thermodynamics; United States; United States Food and Drug Administration | 2011 |
The antifibrotic agent pirfenidone inhibits angiotensin II-induced cardiac hypertrophy in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiomegaly; Fibrosis; Heart; Heart Rate; Hypertension; Male; Mice; Mice, Inbred BALB C; Myocardium; Pyridones | 2012 |
[Effect of qianyang recipe on correlated indices of hypertension rats of gan-yang hyperactivity syndrome].
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcitonin Gene-Related Peptide; Drugs, Chinese Herbal; Hypertension; Male; Medicine, Chinese Traditional; Rats; Rats, Sprague-Dawley; Renin | 2011 |
CYP4A11 T8590C polymorphism, salt-sensitive hypertension, and renal blood flow.
Topics: Adult; Alleles; Angiotensin II; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diet, Sodium-Restricted; Female; Genetic Association Studies; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Polymorphism, Single Nucleotide; Renal Circulation; Sodium Chloride, Dietary | 2011 |
Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; CD11b Antigen; Endothelium, Vascular; Gene Expression; Hypertension; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monocytes; Muramidase; Muscle, Smooth, Vascular; Neutrophils; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Receptors, Chemokine; Respiratory Burst; Vasculitis; Vasoconstrictor Agents | 2011 |
Early life stress enhances angiotensin II-mediated vasoconstriction by reduced endothelial nitric oxide buffering capacity.
Topics: Angiotensin II; Animals; Animals, Newborn; Aorta, Thoracic; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; Maternal Deprivation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Signal Transduction; Stress, Physiological; Vasoconstriction | 2011 |
RAAS Working Group Update. Editorial.
Topics: Angiotensin II; Humans; Hypertension; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2011 |
Differential brain angiotensin-II type I receptor expression in hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Male; Medulla Oblongata; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Subfornical Organ | 2011 |
AT1 receptor-mediated augmentation of angiotensinogen, oxidative stress, and inflammation in ANG II-salt hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Hypertension; Kidney; Male; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary | 2012 |
Blood pressure and renal hemodynamic responses to acute angiotensin II infusion are enhanced in a female mouse model of systemic lupus erythematosus.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Female; Hypertension; Infusions, Intra-Arterial; Kidney; Losartan; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; RNA, Messenger; Vascular Resistance; Vasoconstriction | 2011 |
Increased oxidative stress, the renin-angiotensin system, and sympathetic overactivation induce hypertension in kidney androgen-regulated protein transgenic mice.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Cyclic N-Oxides; Hypertension; Kidney; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Norepinephrine; Oxidative Stress; Proteins; Renin-Angiotensin System; Spin Labels; Sympathetic Nervous System; Transgenes | 2011 |
Possible role of nitric oxide generated by leukocytes in the pathogenesis of hypertensive cerebral edema in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Brain Edema; Cell Adhesion; Endothelial Cells; Hypertension; Inflammation; Leukocytes; Male; Microscopy, Confocal; NF-kappa B; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2011 |
Role of T lymphocytes in angiotensin II-mediated microvascular thrombosis.
Topics: Adoptive Transfer; Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Female; Hypertension; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; NADPH Oxidases; Random Allocation; Reactive Oxygen Species; Sensitivity and Specificity; T-Lymphocytes; Thrombosis | 2011 |
Angiotensin II acts through the angiotensin 1a receptor to upregulate pendrin.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anion Transport Proteins; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Female; Hypertension; Male; Mice; Nitric Oxide; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sulfate Transporters; Tetrazoles; Up-Regulation; Vasoconstrictor Agents | 2011 |
Vascular mechanisms involved in angiotensin II-induced venoconstriction in hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Male; Mesenteric Veins; Portal Vein; Rats; Rats, Inbred SHR; Rats, Wistar; Vasoconstriction | 2011 |
Angiotensin II-dependent hypertension causes reversible changes in the platelet proteome.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Blood Platelets; Humans; Hypertension; Indoles; Male; Mass Spectrometry; Proteome; Proteomics; Rats; Rats, Inbred F344; Renin; Risk Factors | 2011 |
ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension.
Topics: Adenoviridae; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Hypertension; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Telemetry; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
Gαq-protein carboxyl terminus imitation polypeptide GCIP-27 attenuates proliferation of vascular smooth muscle cells and vascular remodeling in spontaneously hypertensive rats.
Topics: 3T3 Cells; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Blood Pressure Determination; Calcium; Cardiotonic Agents; Cell Culture Techniques; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Hypertrophy; Losartan; Male; Mice; Molecular Targeted Therapy; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptides; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Tetrazolium Salts; Thiazoles; Type C Phospholipases; Vasoconstrictor Agents | 2011 |
The role of the subfornical organ in angiotensin II-salt hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Drug Synergism; Heart Rate; Hypertension; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Subfornical Organ; Sympathetic Nervous System | 2012 |
Cerebral microvascular inflammation in DOCA salt-induced hypertension: role of angiotensin II and mitochondrial superoxide.
Topics: Angiotensin II; Animals; Blood Platelets; Blood Pressure; Brain; Cell Adhesion; Cytokines; Desoxycorticosterone; Hypertension; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microvessels; Mineralocorticoids; Mitochondria; Reactive Oxygen Species; Stroke; Superoxides | 2012 |
L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Down-Regulation; Hypertension; Injections, Intravenous; Male; Nifedipine; Rats; Rats, Inbred SHR; Reflex; Renin-Angiotensin System | 2012 |
Antihypertensive effects of ACE2 in the paraventricular nucleus: a consequence of reduced neuroinflammation?
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Genetic Therapy; Humans; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A | 2011 |
COX-2 and angiotensin II-induced hypertension and oxidative stress.
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Hypertension; Male; Oxidative Stress | 2011 |
ETA activation mediates angiotensin II-induced infiltration of renal cortical T cells.
Topics: Angiotensin II; Animals; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Receptor, Endothelin A; T-Lymphocytes | 2011 |
Augmented S-nitrosylation contributes to impaired relaxation in angiotensin II hypertensive mouse aorta: role of thioredoxin reductase.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cyclic GMP; Cysteine; Dinitrochlorobenzene; Disease Models, Animal; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Phenylephrine; S-Nitrosothiols; Thioredoxin-Disulfide Reductase; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Antihypertensive effects of continuous oral administration of nattokinase and its fragments in spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Fibrinogen; Glycine max; Hypertension; Intestinal Absorption; Male; Peptide Hydrolases; Phytotherapy; Plant Extracts; Rats; Rats, Inbred SHR; Soy Foods; Subtilisins | 2011 |
Oxidative stress contributes to sex differences in angiotensin II-mediated hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Kidney; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Sex Characteristics | 2012 |
Identification of a cAMP-response element in the regulator of G-protein signaling-2 (RGS2) promoter as a key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in cultured vascular smooth muscles.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Animals; Cell Nucleus; Cells, Cultured; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Group VI Phospholipases A2; GTP-Binding Protein Regulators; Humans; Hypertension; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Polymorphism, Single Nucleotide; Protein Kinase C; Rabbits; Rats; Response Elements; RGS Proteins; Transcription, Genetic; Up-Regulation; Vasoconstrictor Agents | 2011 |
Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acid.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Biopterins; Blood Pressure; Disease Models, Animal; Folic Acid; Genetic Therapy; GTP Cyclohydrolase; Hypertension; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Mutant Strains; Nitric Oxide; Nitric Oxide Synthase Type III; Tetrahydrofolate Dehydrogenase; Vasoconstrictor Agents; Vitamin B Complex | 2012 |
Role of complement 3a in the synthetic phenotype and angiotensin II-production in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine; Benzhydryl Compounds; Cells, Cultured; Complement C3a; Hypertension; Kruppel-Like Transcription Factors; Muscle, Smooth, Vascular; Phenotype; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Complement; RNA, Messenger | 2012 |
Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Biphenyl Compounds; Blood Pressure; Blotting, Western; Capillaries; Cells, Cultured; Cyclic N-Oxides; Endothelial Cells; Heart Diseases; Hydralazine; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Irbesartan; MAP Kinase Kinase Kinase 5; Myocardial Ischemia; Oxidative Stress; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Spin Labels; Superoxides; Tetrazoles; Ultrasonography; Vascular Endothelial Growth Factor A | 2012 |
Loss of receptor activity-modifying protein 3 exacerbates cardiac hypertrophy and transition to heart failure in a sex-dependent manner.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Diseases; Disease Models, Animal; Female; Gene Expression; Gene Expression Profiling; Gene Knockout Techniques; Genetic Association Studies; Heart Failure; Hypertension; Hypertrophy, Right Ventricular; Kidney Diseases; Male; Mice; Mice, Knockout; Phenotype; Proto-Oncogene Proteins c-akt; Receptor Activity-Modifying Protein 3; Renin; Sex Factors | 2012 |
Angiotensin II-induced hypertension is modulated by nuclear factor-κBin the paraventricular nucleus.
Topics: Angiotensin II; Animals; Hypertension; Male; Nitric Oxide Synthase Type I; Norepinephrine; Oligodeoxyribonucleotides; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin-Angiotensin System; RNA, Messenger; Transcription Factor RelA; Vasoconstrictor Agents | 2012 |
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
Topics: Actins; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cellular Senescence; Eplerenone; Genes, p16; Genes, p53; Hydralazine; Hypertension; Imidazoles; Kidney; Mice; Mice, Inbred C57BL; p21-Activated Kinases; Sirtuin 1; Sodium Chloride; Spironolactone; Tetrazoles | 2012 |
Time-dependent changes in autonomic control of splanchnic vascular resistance and heart rate in ANG II-salt hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Ganglionic Blockers; Heart Rate; Hexamethonium; Hypertension; Male; Pulsatile Flow; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Splanchnic Circulation; Sympathetic Nervous System; Vascular Resistance; Vasoconstrictor Agents; Vasodilation | 2012 |
Angiotensin II augments renal vasoconstriction via AT1 receptors in L-NAME-induced hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Vasoconstriction | 2009 |
Angiotensin II pressor response in the L-NAME-induced hypertensive pithed rat: role of the AT1 receptor.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1 | 2009 |
Angiotensin II receptor activation in youth triggers persistent insulin resistance and hypertension--a legacy effect?
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Body Weight; Chemokine CCL2; Disease Models, Animal; Hypertension; Insulin Resistance; Muscle, Skeletal; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Angiotensin; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2012 |
Angiotensin-(1-7) attenuates angiotensin II-induced cardiac remodeling associated with upregulation of dual-specificity phosphatase 1.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Cardiomegaly; Drug Interactions; Dual Specificity Phosphatase 1; Fibrosis; Hypertension; Male; MAP Kinase Signaling System; Myocardium; Peptide Fragments; Rats; Rats, Sprague-Dawley; Up-Regulation; Vasoconstrictor Agents; Ventricular Remodeling | 2012 |
Lentil polyphenol extract prevents angiotensin II-induced hypertension, vascular remodelling and perivascular fibrosis.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Drinking; Fibrosis; Heart; Hypertension; Kidney; Lens Plant; Male; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Diseases | 2012 |
Importance of rostral ventrolateral medulla neurons in determining efferent sympathetic nerve activity and blood pressure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Chromosomes, Human, Pair 1; Electrophysiological Phenomena; Genetic Loci; Humans; Hypertension; Kidney; Linear Models; Medulla Oblongata; Neurons; Neurons, Efferent; Nonlinear Dynamics; Rats; Rats, Inbred SHR; Sodium; Spinal Cord; Sympathetic Nervous System; Synapses | 2012 |
Reversibility of the effects of aliskiren in the renal versus systemic circulation.
Topics: Adult; Aged; Aldosterone; Amides; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Female; Fumarates; Germany; Half-Life; Humans; Hypertension; Magnetic Resonance Imaging; Male; Middle Aged; Perfusion Imaging; Renal Circulation; Renin; Renin-Angiotensin System; Time Factors; Treatment Outcome; Vasodilation; Vasodilator Agents | 2012 |
Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice.
Topics: Angiotensin II; Animals; Aryl Hydrocarbon Hydroxylases; Blood Pressure; CSK Tyrosine-Protein Kinase; Cytochrome P-450 CYP1B1; Disease Models, Animal; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Hypertension; Kidney; Male; Mice; Mice, Knockout; NADPH Oxidases; Protein-Tyrosine Kinases; Reactive Oxygen Species; Sodium; src-Family Kinases; Vascular Resistance | 2012 |
p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Reactive Oxygen Species; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2012 |
Endogenous aldosterone is involved in vascular calcification in rat.
Topics: Aldosterone; Alkaline Phosphatase; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium; Captopril; Cholecalciferol; Collagen; Fibrosis; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Nicotine; Osteopontin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spironolactone; Vascular Calcification | 2012 |
Angiotensinase and vasopressinase activities in hypothalamus, plasma, and kidney after inhibition of angiotensin-converting enzyme: basis for a new working hypothesis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cystinyl Aminopeptidase; Drinking; Endopeptidases; Hypertension; Hypothalamus; Kidney; Male; Rats; Rats, Wistar | 2012 |
Increased angiotensin II-induced hypertension and inflammatory cytokines in mice lacking angiotensin-converting enzyme N domain activity.
Topics: Angiotensin II; Animals; Blood Pressure; Cytokines; Disease Models, Animal; Hypertension; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Tumor Necrosis Factor-alpha | 2012 |
Sensitization of slow pressor angiotensin II (Ang II)-initiated hypertension: induction of sensitization by prior Ang II treatment.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger | 2012 |
Polymorphisms in the 3'UTR of the human leptin gene and their role in hypertension.
Topics: 3' Untranslated Regions; Adult; Alleles; Angiotensin II; Blood Pressure; Body Mass Index; Female; Genotype; Humans; Hypertension; Leptin; Male; Microsatellite Repeats; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide | 2012 |
Smad3 mediates ANG II-induced hypertensive kidney disease in mice.
Topics: Actins; Albuminuria; Angiotensin II; Animals; Chemokine CCL2; Collagen Type I; Collagen Type IV; Creatinine; Female; Fibronectins; Fibrosis; Hypertension; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta; Ubiquitin-Protein Ligases | 2012 |
Renal sympathetic activation from long-term low-dose angiotensin II infusion in rabbits.
Topics: Angiotensin II; Animals; Baroreflex; Brain; Hypertension; Hypoxia; Norepinephrine; Rabbits; Stress, Psychological; Sympathetic Nervous System; Vasoconstrictor Agents | 2012 |
'Memory' and 'legacy' in hypertension and lifestyle-related diseases.
Topics: Aging; Angiotensin II; Animals; Hypertension; Insulin Resistance; Receptors, Angiotensin | 2012 |
Myocardial migration by fibroblast progenitor cells is blood pressure dependent in a model of angII myocardial fibrosis.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cell Movement; Collagen; Fibroblasts; Fibrosis; Heart; Hypertension; Male; Mice; Myocardium; Renin-Angiotensin System; Stem Cells | 2012 |
Role of renin-angiotensin system and oxidative status on the maternal cardiovascular regulation in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Nitric Oxide Synthase Type III; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
CCR5 deficiency does not reduce hypertensive end-organ damage in mice.
Topics: Angiotensin II; Animals; Chemokine CCL2; Chemokine CCL3; Desoxycorticosterone; Heart; Hypertension; Kidney; Kidney Cortex; Male; Mice; Myocardium; Receptors, CCR5 | 2012 |
Chronic direct renin inhibition with aliskiren prevents the development of hypertension in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent hypertension.
Topics: Amides; Angiotensin II; Animals; Arterial Pressure; Cytochrome P-450 CYP1A1; Fumarates; Hypertension; Kidney; Male; Rats; Rats, Transgenic; Renin | 2012 |
Central infusion of aliskiren prevents sympathetic hyperactivity and hypertension in Dahl salt-sensitive rats on high salt intake.
Topics: Amides; Angiotensin II; Animals; Baroreflex; Blood Pressure; Fumarates; Heart Rate; Hyperkinesis; Hypertension; Infusions, Intraventricular; Male; Rats; Rats, Inbred Dahl; Rats, Wistar; Renin; Sodium Chloride, Dietary; Sympathetic Nervous System | 2012 |
High dietary salt and angiotensin II chronically increase renal sympathetic nerve activity: a direct telemetric study.
Topics: Action Potentials; Angiotensin II; Animals; Baroreflex; Blood Pressure; Chronic Disease; Disease Models, Animal; Female; Follow-Up Studies; Hypertension; Kidney; Male; Rabbits; Sodium Chloride, Dietary; Sympathetic Nervous System; Telemetry | 2012 |
Angiotensin II infusion model of hypertension: is there an important sympathetic component?
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Kidney; Male; Sodium Chloride, Dietary; Sympathetic Nervous System; Telemetry | 2012 |
Pioglitazone ameliorates systolic and diastolic cardiac dysfunction in rat model of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diastole; Disease Models, Animal; Heart Diseases; Hypertension; Hypoglycemic Agents; Male; Pioglitazone; Rats; Rats, Sprague-Dawley; Systole; Thiazolidinediones | 2013 |
Co-effect of insulin resistance and biomarkers of inflammation and endothelial dysfunction on hypertension.
Topics: Adult; Angiotensin II; Asian People; Biomarkers; Blood Glucose; C-Reactive Protein; E-Selectin; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation; Insulin; Insulin Resistance; Intercellular Adhesion Molecule-1; Male; Middle Aged; Prevalence; Risk | 2012 |
Role of angiotensin II-mediated AMPK inactivation on obesity-related salt-sensitive hypertension.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Hypertension; Kidney; Losartan; Metabolic Syndrome; Metformin; Mice; Mice, Inbred C57BL; Obesity; Phosphorylation; Sodium; Sodium, Dietary | 2012 |
Quercetin and catechin synergistically inhibit angiotensin II-induced redox-dependent signalling pathways in vascular smooth muscle cells from hypertensive rats.
Topics: Angiotensin II; Animals; Catechin; Cell Movement; Cell Proliferation; Cells, Cultured; Drug Synergism; Hypertension; MAP Kinase Signaling System; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Quercetin; Rats; Rats, Inbred SHR; Reactive Oxygen Species | 2012 |
Decreased anandamide transporter activity and calcitonin gene-related peptide production in spontaneously hypertensive rats: role of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Endocannabinoids; Ganglia, Spinal; Hypertension; Losartan; Lymphocytes; Male; Membrane Transport Proteins; Polyunsaturated Alkamides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; RNA, Messenger; Up-Regulation | 2012 |
Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Blood Pressure; Cardiomegaly; Constriction, Pathologic; Disease Models, Animal; Elastin; Enzyme Activation; Enzyme Inhibitors; Humans; Hypertension; Losartan; Mice; NADPH Oxidases; Oxidative Stress; Sequence Deletion; Williams Syndrome | 2012 |
The Williams-Beuren Syndrome-a window into genetic variants leading to the development of cardiovascular disease.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Chromosomes, Human, Pair 7; Genetic Variation; Genome, Human; Humans; Hypertension; Mice; Mice, Transgenic; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Reactive Oxygen Species; Sequence Deletion; Williams Syndrome | 2012 |
[Prenatal exposure to lipopolysaccharide results in vascular renin-angiotensin system dysfunction in offspring rats].
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Female; Hypertension; Lipopolysaccharides; Maternal Exposure; Pregnancy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2011 |
RhoA guanine exchange factor expression profile in arteries: evidence for a Rho kinase-dependent negative feedback in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Arteries; Blotting, Western; Feedback, Physiological; Gene Expression Profiling; Guanine Nucleotide Exchange Factors; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Transfection | 2012 |
Expression of heme oxygenase-1 in thick ascending loop of henle attenuates angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Furosemide; Heme Oxygenase-1; Hypertension; Loop of Henle; Mice; Mice, Transgenic; Ouabain; Rubidium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Uromodulin | 2012 |
Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzoates; Blood Pressure; Cardiotonic Agents; Eicosanoids; Epoxide Hydrolases; Female; Hypertension; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Urea | 2012 |
Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats.
Topics: Angiotensin II; Animals; Antioxidants; Catalase; Cytokines; Electron Transport Chain Complex Proteins; Glutathione Peroxidase; Glutathione Transferase; Heart Ventricles; Hemodynamics; Hydrogen; Hypertension; Hypertrophy, Left Ventricular; Male; Malondialdehyde; Mitochondria, Heart; NADPH Oxidases; NF-kappa B; Oxidative Stress; Peroxynitrous Acid; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Sodium Chloride; Superoxide Dismutase | 2012 |
T lymphocytes and vascular inflammation contribute to stress-dependent hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Blood Pressure; Corticotropin-Releasing Hormone; Gene Expression Regulation; Genes, RAG-1; Hypertension; Inflammation; Lymphocyte Activation; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Stress, Psychological; T-Lymphocytes; Vascular Diseases | 2012 |
iPLA2β overexpression in smooth muscle exacerbates angiotensin II-induced hypertension and vascular remodeling.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Blood Pressure; Cell Proliferation; Diastole; Group VI Phospholipases A2; Hypertension; Hypertrophy; Leucine; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Rats; Signal Transduction | 2012 |
Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain.
Topics: Angiotensin II; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Hydrazines; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazepines; Reactive Oxygen Species; Receptor Cross-Talk; Receptors, Prostaglandin E, EP1 Subtype; Signal Transduction; Subfornical Organ | 2012 |
Differential regulation of circulating and renal ACE2 and ACE in hypertensive mRen2.Lewis rats with early-onset diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; Blood Pressure; Blotting, Western; C-Reactive Protein; Chromatography, High Pressure Liquid; Collagen; Diabetes Mellitus, Experimental; Female; Hypertension; Immunohistochemistry; Kidney; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sex Characteristics; Vascular Endothelial Growth Factor A | 2012 |
Reduction of renal lipid content and proteinuria by a PPAR-γ agonist in a rat model of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Ferritins; Gene Expression Regulation; Heme Oxygenase-1; Hypertension; Iron; Kidney; Lipid Metabolism; Male; Pioglitazone; PPAR gamma; Proteinuria; Rats; Rats, Sprague-Dawley; Thiazolidinediones | 2012 |
Control of hypertension in rats using volatile components of leaves of Taxus chinensis var. mairei.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Chromatography, Supercritical Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hydrochlorothiazide; Hypertension; Lipids; Male; Nitric Oxide; Nitroarginine; Phytotherapy; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Taxus; Time Factors; Volatilization | 2012 |
Effects of proangiotensin-12 infused continuously over 14 days in conscious rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Cardiomegaly; Heart; Hypertension; Infusions, Subcutaneous; Male; Myocardium; Organ Size; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Time Factors; Vasoconstrictor Agents; Weight Gain | 2012 |
Experimental selective elevation of renal medullary blood flow in hypertensive rats: evidence against short-term hypotensive effect.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium Chloride | 2012 |
Restoring nitric oxide cytosolic calcium regulation by cyclic guanosine monophosphate protein kinase I alpha transfection in coronary endothelial cells of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Coronary Vessels; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytosol; Hypertension; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Transfection | 2012 |
Role of H(2)O(2) in hypertension, renin-angiotensin system activation and renal medullary disfunction caused by angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Biomarkers; Catalase; Gene Expression Regulation; Hydrogen Peroxide; Hypertension; Kidney Diseases; Kidney Medulla; Male; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2012 |
Blood pressure response to angiotensin II is enhanced in obese Zucker rats and is attributed to an aldosterone-dependent mechanism.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Obesity; Rats; Rats, Zucker | 2012 |
Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.
Topics: Angiotensin II; Animals; Antioxidants; Apoptosis; Boranes; Carbon Dioxide; Carbonates; Catalase; Cells, Cultured; Cytoprotection; Disease Models, Animal; Endothelial Cells; Heme Oxygenase-1; Hemin; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypertension; Hypertrophy; Ischemia; Lung; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Physiologic; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Organometallic Compounds; Oxidative Stress; Polyethylene Glycols; RNA, Messenger; Time Factors; Transfection | 2012 |
Angiotensin converting enzyme 2 contributes to sex differences in the development of obesity hypertension in C57BL/6 mice.
Topics: 3T3-L1 Cells; Adipocytes; Adiposity; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Estrogens; Female; Gene Expression Regulation, Enzymologic; Hypertension; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Progesterone; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Risk Factors; RNA, Messenger; Sex Factors; Testosterone; Time Factors; Weight Gain | 2012 |
Effects of dehydration on cardiovascular development in the embryonic American alligator (Alligator mississipiensis).
Topics: Alligators and Crocodiles; Angiotensin II; Animals; Blood Pressure; Blood Volume; Cardiovascular System; Dehydration; Female; Heart Rate; Hypertension; Receptor, Angiotensin, Type 1; Zygote | 2012 |
Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Angiotensins; Animals; Hypertension; Kidney; Lisinopril; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin | 2012 |
Central cardiovascular circuits contribute to the neurovascular dysfunction in angiotensin II hypertension.
Topics: Angiotensin II; Animals; Cerebrovascular Circulation; Endothelium, Vascular; Gene Transfer Techniques; Hypertension; Male; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Subfornical Organ | 2012 |
Lack of protein kinase C-α leads to impaired urine concentrating ability and decreased aquaporin-2 in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aquaporin 2; Blood Pressure; Cyclic AMP Response Element-Binding Protein; Hypertension; Kidney; Kidney Concentrating Ability; Membrane Transport Proteins; Mice; Mice, Knockout; NFATC Transcription Factors; Phosphorylation; Protein Kinase C-alpha; Urea Transporters | 2012 |
TASK-3 channel deletion in mice recapitulates low-renin essential hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Hyperaldosteronism; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium Channels; Random Allocation; Real-Time Polymerase Chain Reaction; Renin-Angiotensin System; Sensitivity and Specificity; Sequence Deletion; Sodium | 2012 |
Upregulation of the Na(+)-K(+)-2Cl(-) cotransporter 1 via histone modification in the aortas of angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blotting, Western; Bumetanide; Chromatin Immunoprecipitation; Diuretics; Histone Demethylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Up-Regulation; Vasoconstrictor Agents | 2012 |
Modeling of angiotensin II-angiotensin-(1-7) counterbalance in disease progression in spontaneously hypertensive rats treated with/without perindopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Models, Biological; Peptide Fragments; Perindopril; Rats; Rats, Inbred SHR | 2012 |
Brain-targeted (pro)renin receptor knockdown attenuates angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Baroreflex; Blood Pressure; Blotting, Western; Brain; Cell Line, Tumor; Humans; Hypertension; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Vasopressins | 2012 |
Antihypertensive effect of gomisin A from Schisandra chinensis on angiotensin II-induced hypertension via preservation of nitric oxide bioavailability.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blood Vessels; Cells, Cultured; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Hypertension; Lignans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Reactive Oxygen Species; Schisandra; Vasoconstrictor Agents | 2012 |
Protein kinase C-α comes to the rescue of aquaporin-2.
Topics: Angiotensin II; Animals; Aquaporin 2; Hypertension; Kidney; Kidney Concentrating Ability; Membrane Transport Proteins; Protein Kinase C-alpha; Urea Transporters | 2012 |
Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cytochrome P-450 CYP1A1; Hydrochlorothiazide; Hypertension; Kidney Tubules, Distal; Losartan; Male; Microvessels; Natriuresis; Rats; Rats, Transgenic; Renin; Sodium Chloride Symporters; Spironolactone | 2012 |
The Mas receptor mediates modulation of insulin signaling by angiotensin-(1-7).
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dyslipidemias; Fructose; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; GTPase-Activating Proteins; Hypertension; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction | 2012 |
Exercise training causes sympathoinhibition through antioxidant effect in the rostral ventrolateral medulla of hypertensive rats.
Topics: Angiotensin II; Animals; Antioxidants; Baroreflex; Blood Pressure; Cyclic N-Oxides; Heart Rate; Hypertension; Male; Medulla Oblongata; Norepinephrine; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Spin Labels; Sympathetic Nervous System; Thiobarbituric Acid Reactive Substances | 2012 |
Increased neuronal activity in the OVLT of Cyp1a1-Ren2 transgenic rats with inducible Ang II-dependent malignant hypertension.
Topics: Action Potentials; Angiotensin II; Animals; Cytochrome P-450 CYP1A1; Hypertension; Hypothalamus; Male; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System; Sensory Receptor Cells; Water-Electrolyte Balance | 2012 |
Long-term alteration in maternal blood pressure and renal function after pregnancy in normal and growth-restricted rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Body Weight; Female; Fetal Growth Retardation; Glomerular Filtration Rate; Hypertension; Kidney; Male; Placental Insufficiency; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred WKY; Renal Circulation; Renin; Time Factors; Vascular Resistance | 2012 |
Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Brain; Cerebral Arteries; Cerebrovascular Circulation; Endothelium, Vascular; Female; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Protein Isoforms; Reactive Oxygen Species | 2012 |
Chronic infusion of angiotensin-(1-7) into the lateral ventricle of the brain attenuates hypertension in DOCA-salt rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Collagen Type I; Collagen Type III; Desoxycorticosterone; Disease Models, Animal; Heart Rate; Heart Ventricles; Hypertension; Infusions, Intraventricular; Kidney; Lateral Ventricles; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathetic Nervous System; Time Factors | 2012 |
Basal and postprandial serum levels of gastrin in normotensive and hypertensive adults.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Case-Control Studies; Fasting; Female; Gastrins; Humans; Hypertension; Male; Postprandial Period; Renin; Renin-Angiotensin System; Water-Electrolyte Balance | 2013 |
[Hypertension-induced fibrosis: a balance story].
Topics: Aldosterone; Angiotensin II; Animals; Bone Morphogenetic Proteins; Cardiomegaly; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Failure; Hypertension; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Natriuretic Peptide, Brain; Renin; Renin-Angiotensin System | 2012 |
[Effect of yanggan yishui granule on plasma Ang II, TGF-beta1, CTGF content, and renal cortical Ang II , TGF-beta1, and CTGF mRNA expressions in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Connective Tissue Growth Factor; Drugs, Chinese Herbal; Hypertension; Kidney Cortex; Male; Phytotherapy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Transforming Growth Factor beta1 | 2012 |
Blood pressure and renin-angiotensin system resetting in transgenic rats with elevated plasma Val5-angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Feedback, Physiological; Genotype; Hypertension; Kidney; Lisinopril; Male; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System | 2012 |
Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cell Line; Cyclic GMP; Cysteine; Disease Models, Animal; Enzyme Activation; Guanylate Cyclase; Hypertension; Male; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Nitrosation; Oxidative Stress; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Time Factors; Transfection; Vascular Resistance; Vasodilation | 2012 |
Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Male; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Recombinant Proteins | 2013 |
Excessive zinc intake increases systemic blood pressure and reduces renal blood flow via kidney angiotensin II in rats.
Topics: Angiotensin II; Animals; Arterial Pressure; Carbonates; Down-Regulation; Glomerular Filtration Rate; Hypertension; Inulin; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renal Circulation; Renal Insufficiency; Renin-Angiotensin System; Up-Regulation; Zinc; Zinc Compounds | 2012 |
Role of copper transport protein antioxidant 1 in angiotensin II-induced hypertension: a key regulator of extracellular superoxide dismutase.
Topics: Adenosine Triphosphatases; Angiotensin II; Animals; Aorta; Blood Pressure; Cation Transport Proteins; Copper; Copper Transport Proteins; Copper-Transporting ATPases; Disease Models, Animal; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Chaperones; Muscle, Smooth, Vascular; Oxygen; Superoxide Dismutase | 2012 |
Antioxidant 1 in hypertension: more than just a copper chaperone.
Topics: Angiotensin II; Animals; Cation Transport Proteins; Copper Transport Proteins; Female; Hypertension; Male; Molecular Chaperones; Superoxide Dismutase | 2012 |
Therapeutic potential of Schisandra chinensis extracts for treatment of hypertension. Introduction to: 'antihypertensive effect of gomisin A from Schisandra chinensis on angiotensin II-induced hypertension via preservation of nitric oxide bioavailability'
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cyclooctanes; Dioxoles; Hypertension; Lignans; Male; Nitric Oxide; Schisandra; Vasoconstrictor Agents | 2012 |
Relaxant effect of a water soluble carbon monoxide-releasing molecule (CORM-3) on spontaneously hypertensive rat aortas.
Topics: Angiotensin II; Animals; Aorta; Carbon Monoxide; Charybdotoxin; Endothelin-1; Endothelium, Vascular; Guanylate Cyclase; Hypertension; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Organometallic Compounds; Potassium Channels, Calcium-Activated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; S-Nitroso-N-Acetylpenicillamine; Soluble Guanylyl Cyclase; Vasoconstriction; Vasodilation; Vasodilator Agents; Water | 2012 |
Murine recombinant angiotensin-converting enzyme 2: effect on angiotensin II-dependent hypertension and distinctive angiotensin-converting enzyme 2 inhibitor characteristics on rodent and human angiotensin-converting enzyme 2.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Humans; Hydrolysis; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Leucine; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Recombinant Proteins | 2012 |
[Differences of blood plasma renin activity, angiotensin II and aldosterone levels in essential or secondary hypertension].
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; Young Adult | 2012 |
The effects of phentolamine on fructose-fed rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Fructose; Hypertension; Insulin; Male; Metabolic Syndrome; Norepinephrine; Phentolamine; Rats; Rats, Wistar; Reactive Nitrogen Species; Uric Acid | 2012 |
Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors.
Topics: Analgesics; Angiotensin II; Animals; Arteries; Benzoxazines; Endocannabinoids; Endothelium, Vascular; Hypertension; Male; Mice; Mice, Knockout; Morpholines; Muscle, Skeletal; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Vasoconstriction | 2012 |
Angiotensin II contributes to renal fibrosis independently of Notch pathway activation.
Topics: Angiotensin II; Animals; Calcium-Binding Proteins; Cell Line; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Hydronephrosis; Hypertension; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Kidney; Kidney Tubules; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Podocytes; Rats; Receptor, Angiotensin, Type 1; Receptors, Notch; Serrate-Jagged Proteins; Signal Transduction; Transforming Growth Factor beta1 | 2012 |
Sexual dimorphism in urinary angiotensinogen excretion during chronic angiotensin II-salt hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension; Kidney; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sex Factors; Sodium Chloride, Dietary | 2012 |
Sex-specific programming of hypertension in offspring of late-gestation diabetic rats.
Topics: Age Factors; Angiotensin II; Animals; Baroreflex; Blood Pressure; Diabetes Mellitus, Experimental; Diabetes, Gestational; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ganglionic Blockers; Gestational Age; Heart Rate; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase; Phenotype; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Factors; Signal Transduction; Streptozocin; Superoxide Dismutase; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2012 |
Effect of the flavonoid fraction of Lithocarpus polystachyus Rehd. on spontaneously hypertensive and normotensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Endothelins; Fagaceae; Flavonoids; Hypertension; Male; Malondialdehyde; Microcirculation; Nitric Oxide; Phytotherapy; Plant Extracts; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renin; Skin; Superoxide Dismutase | 2012 |
Influence of arterial hypertension on colonic healing in rats.
Topics: Anastomosis, Surgical; Angiotensin II; Animals; Blood Pressure; Collagen; Colon; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypertension; Male; Postoperative Period; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Surgical Wound Dehiscence; Time Factors; Wound Healing | 2012 |
N-type calcium channel inhibition with cilnidipine elicits glomerular podocyte protection independent of sympathetic nerve inhibition.
Topics: Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cell Line; Desmin; Dihydropyridines; Hypertension; Male; Mice; Podocytes; Protective Agents; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System | 2012 |
Death-associated protein kinase 3 mediates vascular inflammation and development of hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Apoptosis Regulatory Proteins; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinases; Death-Associated Protein Kinases; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Mesenteric Arteries; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2012 |
A new conceptual paradigm for the haemodynamics of salt-sensitive hypertension: a mathematical modelling approach.
Topics: Angiotensin II; Animals; Arterial Pressure; Computer Simulation; Hemodynamics; Hypertension; Kidney; Models, Biological; Sodium | 2012 |
Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension.
Topics: Angiotensin II; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Hypertension; Immunity, Innate; Inflammation; Macrophages; Male; Neurotransmitter Agents; Nicotine; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spleen | 2012 |
An increase in perfusion pressure and activation of the renin-angiotensin system in the pathogenesis of hypertension and injury: strain vessels and the cerebrovascular-renal connection.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Blood Pressure; Cerebrovascular Circulation; Humans; Hypertension; Kidney; Rats; Renal Circulation; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2012 |
Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Dual Specificity Phosphatase 1; Gene Expression Regulation; Hypertension; Ion Channels; JNK Mitogen-Activated Protein Kinases; Male; Medulla Oblongata; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Oligonucleotides, Antisense; Oxidative Stress; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Signal Transduction; Uncoupling Protein 2 | 2012 |
Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterial Pressure; Biomarkers; Blood Vessels; Case-Control Studies; Cell Adhesion Molecules; Cell Line; Disease Models, Animal; Humans; Hydralazine; Hypertension; Hypertension, Renovascular; Losartan; Male; Morpholinos; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cell Surface; RNA, Messenger; Time Factors; Up-Regulation; Vasodilator Agents | 2012 |
Adverse cardiac remodelling in spontaneously hypertensive rats: acceleration by high aerobic exercise intensity.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Female; Hypertension; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Wistar; Risk Factors; Ventricular Remodeling | 2012 |
Aldosterone acting through the central nervous system sensitizes angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Hypertension; Hypothalamus; Male; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Telemetry | 2012 |
Impaired left ventricular function in the presence of preserved ejection in chronic hypertensive conscious pigs.
Topics: Angiotensin II; Animals; Diastole; Female; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Myocardial Contraction; Swine; Ventricular Function, Left | 2012 |
Role of the transcription factor erythroblastosis virus E26 oncogen homolog-1 (ETS-1) as mediator of the renal proinflammatory and profibrotic effects of angiotensin II.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Fibrosis; Gene Expression; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Inflammation; Ki-67 Antigen; Kidney; Kidney Cortex; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; NADPH Oxidase 4; NADPH Oxidases; Peptides; Proto-Oncogene Protein c-ets-1; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Methylglyoxal accumulation in arterial walls causes vascular contractile dysfunction in spontaneously hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Endothelium, Vascular; Glycation End Products, Advanced; Guanidines; Hypertension; In Vitro Techniques; Mesenteric Arteries; Nitroprusside; Pyruvaldehyde; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Vasoconstriction; Vasodilation | 2012 |
Renin-angiotensin system modulates neurotransmitters in the paraventricular nucleus and contributes to angiotensin II-induced hypertensive response.
Topics: Angiotensin II; Animals; Hypertension; Male; Neurotransmitter Agents; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2013 |
[Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms].
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Pressure; Drugs, Chinese Herbal; Endothelin-1; Hypertension; Male; Norepinephrine; Phytotherapy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Scrophularia; Thromboxane B2 | 2012 |
[Inhibitory effect of losartan on prostatic hyperplasia in spontaneous hypertension rats and its pathophysiological mechanism].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Hypertension; Insulin-Like Growth Factor I; Interleukin-6; Losartan; Male; Nitric Oxide Synthase Type III; Prostate; Prostatic Hyperplasia; Rats; Rats, Inbred SHR | 2012 |
Captopril avoids hypertension, the increase in plasma angiotensin II but increases angiotensin 1-7 and angiotensin II-induced perfusion pressure in isolated kidney in SHR.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Peptide Fragments; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Specific Pathogen-Free Organisms; Vascular Resistance | 2012 |
EP1 disruption attenuates end-organ damage in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Female; Humans; Hydralazine; Hypertension; Kaplan-Meier Estimate; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Receptors, Prostaglandin E, EP1 Subtype | 2012 |
Angiotensin II induced differentially expressed microRNAs in adult rat cardiac fibroblasts.
Topics: Angiotensin II; Animals; Computational Biology; Down-Regulation; Fibroblasts; Heart; Hypertension; Male; Matrix Metalloproteinase 16; Matrix Metalloproteinase 9; MicroRNAs; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-3; Up-Regulation | 2013 |
Enhanced adipose afferent reflex contributes to sympathetic activation in diet-induced obesity hypertension.
Topics: Adipose Tissue, White; Angiotensin II; Animals; Blood Pressure; Capsaicin; Diet, High-Fat; Diterpenes; Enzyme-Linked Immunosorbent Assay; Hypertension; Immunohistochemistry; Lidocaine; Male; Norepinephrine; Obesity; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reflex; Renin; Sensory System Agents; Sympathetic Nervous System | 2012 |
Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Animals, Newborn; Autonomic Nervous System; Blood Pressure; Bone Marrow; Brain; Cells, Cultured; Endothelial Cells; Flow Cytometry; Green Fluorescent Proteins; Hematopoietic Stem Cells; Hypertension; Infusions, Intraventricular; Lymphocytes; Macrophages; Male; Neurons; Organophosphorus Compounds; Paraventricular Hypothalamic Nucleus; Piperidines; Rats; Rats, Sprague-Dawley | 2012 |
Low-dose dextromethorphan, a NADPH oxidase inhibitor, reduces blood pressure and enhances vascular protection in experimental hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Line; Dextromethorphan; Heart Rate; Humans; Hypertension; Male; NADPH Oxidases; Random Allocation; Rats; Rats, Inbred WKY; Reactive Oxygen Species | 2012 |
Sodium nitrite therapy rescues ischemia-induced neovascularization and blood flow recovery in hypertension.
Topics: Allopurinol; Angiotensin II; Animals; Arterial Pressure; Capillaries; Cyclic AMP; Cyclic GMP; Femoral Artery; Hindlimb; Hypertension; Indoles; Ischemia; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Regional Blood Flow; Sodium Nitrite; Xanthine Dehydrogenase | 2012 |
Irbesartan and emodin on myocardial remodeling in Goldblatt hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Connective Tissue Growth Factor; Drug Therapy, Combination; Emodin; Gene Expression Regulation; Hypertension; Irbesartan; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta1; Ventricular Remodeling | 2012 |
ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension.
Topics: Angiotensin II; Animals; Brain; Cholagogues and Choleretics; Chronic Disease; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Hypertension; Mice; Subfornical Organ; Taurochenodeoxycholic Acid; Vasoconstrictor Agents | 2012 |
Endoplasmic reticulum stress and hypertension - a new paradigm?
Topics: Angiotensin II; Animals; Brain; Endoplasmic Reticulum Stress; Hypertension; Vasoconstrictor Agents | 2012 |
Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of losartan and amlodipine regarding long-term blood pressure, cardiac and renal protection.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Collagen; Gene Expression Regulation; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Kidney; Losartan; Male; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stroke Volume; Transforming Growth Factor beta1; Ultrasonography | 2012 |
Oxidative stress exaggerates skeletal muscle contraction-evoked reflex sympathoexcitation in rats with hypertension induced by angiotensin II.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Afferent Pathways; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Pressure; Blotting, Western; Cardiovascular System; Cyclic N-Oxides; Decerebrate State; Disease Models, Animal; Electric Stimulation; Heart Rate; Hindlimb; Hypertension; Injections, Intra-Articular; Kidney; Losartan; Male; Membrane Glycoproteins; Muscle Contraction; Muscle, Skeletal; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reflex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spin Labels; Superoxides; Sympathetic Nervous System; Time Factors | 2013 |
Aneurysm formation in proinflammatory, transgenic haptoglobin 2-2 mice.
Topics: Angiotensin II; Animals; Blood Pressure; Carotid Arteries; Carotid Artery Diseases; Genotype; Haptoglobins; Hypertension; Immunohistochemistry; Intracranial Aneurysm; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neutrophil Infiltration; Pancreatic Elastase | 2013 |
SOD1 gene transfer into paraventricular nucleus attenuates hypertension and sympathetic activity in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Gene Expression; Gene Targeting; Genetic Vectors; Heart Ventricles; Humans; Hypertension; Male; Myocytes, Cardiac; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Wistar; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Sympathetic Nervous System; Up-Regulation | 2013 |
Clustering of inflammatory biomarkers and risk of hypertension in a Mongolian population in China.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Asian People; C-Reactive Protein; China; Female; Genetic Markers; Genetic Predisposition to Disease; Humans; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Male; Middle Aged; Young Adult | 2012 |
Angiotensin-(1-7) modulates renin-angiotensin system associated with reducing oxidative stress and attenuating neuronal apoptosis in the brain of hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Hypertension; Male; Malondialdehyde; Neurons; Nitric Oxide Synthase Type II; Oxidative Stress; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Superoxide Dismutase | 2013 |
The β3 subunit contributes to vascular calcium channel upregulation and hypertension in angiotensin II-infused C57BL/6 mice.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Calcium Channels, L-Type; Hypertension; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Up-Regulation | 2013 |
Proteasome inhibition attenuates heart failure during the late stages of pressure overload through alterations in collagen expression.
Topics: Angiotensin II; Animals; Cells, Cultured; Collagen; Disease Models, Animal; Down-Regulation; Fibrosis; Heart Failure; Heart Ventricles; Hypertension; Leupeptins; Male; Proteasome Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Severity of Illness Index; Signal Transduction; Transforming Growth Factor beta1; Ubiquitin; Ventricular Dysfunction, Left | 2013 |
Angiotensin II induces TSLP via an AT1 receptor/NF-KappaB pathway, promoting Th17 differentiation.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Atherosclerosis; Cell Differentiation; Cells, Cultured; Cytokines; Dendritic Cells; Gene Expression; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Th17 Cells; Thymic Stromal Lymphopoietin; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2012 |
Effects of endothelin receptor antagonists on renal hemodynamics in angiotensin II-infused rats on high NaCl intake.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelin Receptor Antagonists; Hemodynamics; Hypertension; Kidney; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sodium Chloride, Dietary | 2012 |
Early life stress induces renal dysfunction in adult male rats but not female rats.
Topics: Age Factors; Aging; Angiotensin II; Animals; Anxiety, Separation; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Creatinine; Disease Models, Animal; Estradiol; Female; Hypertension; Kidney; Kidney Diseases; Male; Maternal Deprivation; Orchiectomy; Proteinuria; Rats; Rats, Inbred WKY; Sex Factors; Stress, Psychological; Telemetry; Testosterone | 2013 |
Angiotensin II promotes aortic valve thickening independent of elevated blood pressure in apolipoprotein-E deficient mice.
Topics: Angiotensin II; Animals; Aortic Valve; Aortic Valve Stenosis; Apolipoproteins E; Atherosclerosis; Hypertension; Male; Mice; Mice, Inbred C57BL | 2013 |
Effects of angiotensin-converting enzyme inhibitory peptide LAP on vascular remodeling.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blood Vessels; Cell Nucleus Size; Collagen; Drug Design; Enalapril; Hypertension; Male; Oligopeptides; Rats; Rats, Inbred SHR; Tunica Media | 2013 |
Effect of oxymatrine, the active component from Radix Sophorae flavescentis (Kushen), on ventricular remodeling in spontaneously hypertensive rats.
Topics: Alkaloids; Angiotensin II; Animals; Anti-Arrhythmia Agents; Blood Pressure; Collagen; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Heart; Heart Rate; Hypertension; Male; MAP Kinase Signaling System; Myocardium; Norepinephrine; Organ Size; Peptidyl-Dipeptidase A; Phytotherapy; Quinolizines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Transforming Growth Factor beta1; Ventricular Remodeling | 2013 |
Sex differences in the biomechanics and contractility of intramural coronary arteries in angiotensin II-induced hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Biomechanical Phenomena; Bradykinin; Coronary Vessels; Elastic Modulus; Female; Hypertension; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Sex Factors; Vasoconstrictor Agents; Vasodilator Agents | 2012 |
Roles played by 20-HETE, angiotensin II and endothelin in mediating the hypertension in aging female spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Endothelins; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Rats; Rats, Inbred SHR | 2013 |
Hemodynamic and hormonal changes to dual renin-angiotensin system inhibition in experimental hypertension.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Fumarates; Heart Rate; Hemodynamics; Hypertension; Kidney; Male; Rats; Renin; Renin-Angiotensin System; Telemetry; Tetrazoles; Valine; Valsartan | 2013 |
Differential baseline expression and angiotensin II-stimulation of leukemia-associated RhoGEF in vascular smooth muscle cells of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Cells, Cultured; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Wistar; Rho Guanine Nucleotide Exchange Factors | 2012 |
Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Inflammation; Integrases; Mice; Mice, Transgenic; NADPH Oxidases; Oxidation-Reduction; Protein Subunits; Reactive Oxygen Species; Subfornical Organ | 2013 |
Angiotensin II-induced hypertension dose-dependently leads to oxidative stress and DNA damage in mouse kidneys and hearts.
Topics: Angiotensin II; Animals; Apoptosis; Chromatography, Liquid; DNA Damage; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hypertension; Immunohistochemistry; Kidney; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Myocardium; Oxidative Stress | 2013 |
Protective role of vascular smooth muscle cell PPARγ in angiotensin II-induced vascular disease.
Topics: Angiotensin II; Animals; Chemokine CCL2; Disease Models, Animal; Endothelium, Vascular; Hypertension; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; NADP; Oxidative Stress; PPAR gamma; Superoxide Dismutase; Vascular Diseases | 2013 |
Increased circulating ANG II and TNF-α represents important risk factors in obese saudi adults with hypertension irrespective of diabetic status and BMI.
Topics: Adult; Angiotensin II; Blood Pressure; Body Mass Index; Diabetes Complications; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Risk Factors; Saudi Arabia; Tumor Necrosis Factor-alpha | 2012 |
Small-molecule inhibitors of signal transducer and activator of transcription 3 protect against angiotensin II-induced vascular dysfunction and hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aminosalicylic Acids; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Benzenesulfonates; Carotid Arteries; Cyclic S-Oxides; Endothelium, Vascular; Hypertension; Male; Mice; Nitroprusside; Oxidative Stress; Phosphorylation; STAT3 Transcription Factor; Superoxides; Vasoconstrictor Agents; Vasodilator Agents | 2013 |
Immunosuppression preserves renal autoregulatory function and microvascular P2X(1) receptor reactivity in ANG II-hypertensive rats.
Topics: Adenosine Triphosphate; Albuminuria; Angiotensin II; Animals; Arterioles; Homeostasis; Hypertension; Immunosuppression Therapy; Immunosuppressive Agents; Lymphocyte Activation; Lymphocytes; Macrophages; Male; Mycophenolic Acid; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X1; Renal Circulation; Transforming Growth Factor beta1 | 2013 |
Mild hypercholesterolemia blunts the proinflammatory and prothrombotic effects of hypertension on the cerebral microcirculation.
Topics: Angiotensin II; Animals; Apolipoprotein A-I; Blood-Brain Barrier; Cerebrovascular Circulation; Disease Models, Animal; Humans; Hypercholesterolemia; Hypertension; Lipoproteins, HDL; Male; Mice; Mice, Transgenic; Microcirculation; Vasoconstrictor Agents; Venules | 2013 |
Cholecalciferol administration blunts the systemic renin-angiotensin system in essential hypertensives with hypovitaminosis D.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Cholecalciferol; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Vitamin D; Vitamin D Deficiency | 2014 |
Aberrant endoplasmic reticulum stress in vascular smooth muscle increases vascular contractility and blood pressure in mice deficient of AMP-activated protein kinase-α2 in vivo.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Enzyme Activation; Enzyme Activators; Humans; Hypertension; Leupeptins; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myosin Light Chains; Nitric Oxide Synthase Type III; Phenylbutyrates; Phenylephrine; Phosphorylation; Ribonucleotides; Taurochenodeoxycholic Acid; Time Factors; Tunicamycin; Vasoconstriction; Vasoconstrictor Agents | 2013 |
Maternal caffeine administration leads to adverse effects on adult mice offspring.
Topics: Angiotensin II; Animals; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Female; Heart; Hypertension; Kidney; Male; Maternal Exposure; Mice; Mice, Inbred C57BL; Pregnancy; Renin; Renin-Angiotensin System | 2013 |
Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice.
Topics: Angiotensin II; Animals; Fibrosis; Gene Expression Regulation; Hypertension; Inflammation; Kidney; Kidney Diseases; Male; Mice; Mice, Knockout; MicroRNAs; NF-kappa B; Proteinuria; Signal Transduction; Smad3 Protein; Smad7 Protein; Sp1 Transcription Factor; Transforming Growth Factor beta | 2013 |
Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Enzyme Inhibitors; Epoxide Hydrolases; Hypertension; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Transgenic; Thiobarbituric Acid Reactive Substances | 2013 |
Chronic angiotensin-II treatment potentiates HR slowing in Sprague-Dawley rat during acute behavioral stress.
Topics: Angiotensin II; Animals; Avoidance Learning; Behavior, Animal; Blood Pressure; Bradycardia; Cardiovascular System; Disease Models, Animal; Drug Implants; Heart Rate; Hypertension; Male; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stress, Psychological | 2013 |
Role of STAT3 in angiotensin II-induced hypertension and cardiac remodeling revealed by mice lacking STAT3 serine 727 phosphorylation.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Collagen; Cytokines; Electrocardiography; Fibrosis; Heart; Hemodynamics; Hypertension; Ischemic Preconditioning, Myocardial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Phosphorylation; Serine; STAT3 Transcription Factor; Vasoconstrictor Agents | 2013 |
Apelin effects on blood pressure and RAS in DOCA-salt-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Aorta; Apelin; Apelin Receptors; Blood Pressure; Desoxycorticosterone Acetate; Endothelin-1; Hypertension; Intercellular Signaling Peptides and Proteins; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger | 2013 |
Peroxisome proliferator-activated receptor-γ mutations responsible for lipodystrophy with severe hypertension activate the cellular renin-angiotensin system.
Topics: Adult; Aged; Amino Acid Sequence; Angiotensin II; Anilides; Animals; Case-Control Studies; Enzyme Activation; Female; Fibroblasts; Genetic Predisposition to Disease; HEK293 Cells; Humans; Hypertension; Inflammation Mediators; Leukocytes, Mononuclear; Lipodystrophy, Familial Partial; Male; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; Oxidative Stress; Phenotype; PPAR gamma; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA Interference; Rosiglitazone; Severity of Illness Index; Skin; Thiazolidinediones; Transfection; Young Adult | 2013 |
1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Calcitriol; Drinking Behavior; Gene Expression; Hypertension; Hypocalcemia; In Vitro Techniques; Mice; Mice, Knockout; Neuropeptides; Promoter Regions, Genetic; Receptors, Calcitriol; Renin; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Sodium, Dietary; Trans-Activators | 2002 |
Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor.
Topics: Adrenomedullin; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzazepines; Biomarkers; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Heart; Hypertension; Male; Models, Cardiovascular; Neprilysin; Organ Size; Peptides; Pyridines; Ramipril; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, Bradykinin; Severity of Illness Index; Systole; Treatment Outcome; Vasoconstrictor Agents | 2002 |
Decreased monoamine release in the median preoptic area following ventricular treatment with the angiotensin II antagonist saralasin in normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Biogenic Monoamines; Hypertension; Injections, Intraventricular; Male; Microdialysis; Neural Pathways; Neurons; Preoptic Area; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Saralasin; Subfornical Organ | 2002 |
Endothelin receptor antagonist combined with a calcium channel blocker attenuates renal injury in spontaneous hypertensive rats with diabetes.
Topics: Amlodipine; Angiotensin II; Animals; Bosentan; Calcium Channel Blockers; Collagen Type IV; Diabetic Nephropathies; Drug Therapy, Combination; Endothelin Receptor Antagonists; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcineurin; Cardiomegaly; Echocardiography; Fibrosis; Gene Expression Regulation; Hypertension; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Stress, Mechanical; Tacrolimus; Tetrazoles; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense.
Topics: Angiotensin II; Animals; Blood Pressure; ErbB Receptors; Hypertension; Hypertrophy, Left Ventricular; Kinetics; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Sprague-Dawley | 2002 |
Role of endothelin receptors in the hypertensive state of kinin B(2) knockout mice subjected to a high-salt diet.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Hypertension; Kidney; Losartan; Male; Mice; Mice, Knockout; Myocardium; Oligopeptides; Peptides, Cyclic; Piperidines; Protein Precursors; Receptor, Bradykinin B2; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Angiotensin; Receptors, Bradykinin; Receptors, Endothelin; RNA, Messenger; Sodium Chloride, Dietary | 2002 |
Angiotensin signaling and apoptosis in the neonatal heart: necessary evils?
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Apoptosis; Female; Fetus; Heart; Humans; Hypertension; Infant, Newborn; Myocytes, Cardiac; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Angiotensin; Signal Transduction | 2002 |
Neural control of the renal vasculature in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Electric Stimulation; Female; Hypertension; Kidney; Male; Rabbits; Sympathetic Fibers, Postganglionic | 2002 |
No morbidity-mortality. Commentary.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Atenolol; Diabetes Complications; Diabetes Mellitus; Follow-Up Studies; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Middle Aged; Morbidity; Patient Selection | 2002 |
Augmented upregulation by c-fos of angiotensin subtype 1 receptor in nucleus tractus solitarii of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Immunohistochemistry; Male; Microinjections; Oligonucleotides, Antisense; Pressoreceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Solitary Nucleus; Transcriptional Activation; Up-Regulation; Vasoconstrictor Agents | 2002 |
Diuretic response to acute hypertension is blunted during angiotensin II clamp.
Topics: Acute Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diuresis; Drug Synergism; Hypertension; Kidney; Lithium; Male; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2 | 2002 |
Is cardiovascular remodeling in patients with essential hypertension related to more than high blood pressure? A LIFE substudy. Losartan Intervention For Endpoint-Reduction in Hypertension.
Topics: Aged; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood Vessels; Cardiovascular Physiological Phenomena; Carotid Arteries; Echocardiography; Epinephrine; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Smooth, Vascular; Plethysmography, Impedance; Regression Analysis; Vascular Resistance; Ventricular Remodeling | 2002 |
Diabetic nephropathy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Creatine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension | 2002 |
Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Fibrosis; Gene Targeting; Guanylate Cyclase; Heart Rate; Heart Ventricles; Hypertension; Imidazoles; Mice; Mice, Knockout; Myocardium; Natriuretic Peptide, Brain; Olmesartan Medoxomil; Organ Size; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Ventricular Remodeling | 2002 |
Cardiovascular responses to angiotensin II in atherosclerosis.
Topics: Angiotensin II; Animals; Arteriosclerosis; Blood Pressure; Cardiac Output, Low; Diet, Atherogenic; Female; Hypertension; Lipids; Male; Rabbits; Vasoconstrictor Agents | 2002 |
Iron overload augments angiotensin II-induced cardiac fibrosis and promotes neointima formation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Drug Synergism; Fibrosis; Heart; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hypertension; Immunohistochemistry; Iron Chelating Agents; Iron Overload; Iron-Dextran Complex; Losartan; Male; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tunica Intima; Vasodilator Agents | 2002 |
Autoantibodies against AT1-receptor and alpha1-adrenergic receptor in patients with hypertension.
Topics: Angiotensin II; Autoantibodies; Catecholamines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypertension; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Renin; Sensitivity and Specificity | 2002 |
Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cells, Cultured; Endothelium, Vascular; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Superoxides | 2002 |
Hemodynamic and humoral effects of vasopeptidase inhibition in canine hypertension.
Topics: Adrenomedullin; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Dogs; Fosinopril; Hemodynamics; Hypertension; Kinetics; Male; Neprilysin; Peptides; Protease Inhibitors; Pyridines; Thiazepines; Vasoconstrictor Agents | 2002 |
Ventrolateral medulla AT1 receptors support blood pressure in hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypertension; Injections; Kynurenic Acid; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 2002 |
Rostral ventrolateral medulla neurons of neonatal Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Brain Stem; Cells, Cultured; Hypertension; Kinetics; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Spinal Cord; Tetrazoles | 2002 |
"Sausage-string" appearance of arteries and arterioles can be caused by an instability of the blood vessel wall.
Topics: Algorithms; Angiotensin II; Animals; Anisotropy; Arteries; Arterioles; Blood Pressure; Computer Simulation; Elasticity; Hypertension; Kinetics; Male; Models, Biological; Norepinephrine; Perfusion; Rats; Rats, Wistar; Stress, Mechanical; Vasoconstrictor Agents | 2002 |
Activation of hypothalamic angiotensin receptors produces pressor responses via cholinergic inputs to the rostral ventrolateral medulla in normotensive and hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carbachol; Cholinergic Agonists; Cholinergic Fibers; Cholinesterase Inhibitors; Electric Stimulation; gamma-Aminobutyric Acid; Hypertension; Hypothalamus, Anterior; Iontophoresis; Losartan; Male; Medulla Oblongata; Microinjections; Muscarinic Antagonists; Neural Pathways; Physostigmine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Scopolamine; Vasoconstrictor Agents | 2002 |
Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Progression; Echocardiography; Enzyme Activation; Heart Failure; Hypertension; Male; Myocardium; Organ Size; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Inbred Dahl; Stress, Mechanical; Tetrazoles; Valine; Valsartan; Ventricular Function, Left | 2002 |
Maternal glucocorticoid treatment programs alterations in the renin-angiotensin system of the ovine fetal kidney.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blotting, Western; Dexamethasone; Diuresis; Female; Gestational Age; Glomerular Filtration Rate; Glucocorticoids; Hydrocortisone; Hypertension; Immunohistochemistry; Kidney; Maternal-Fetal Exchange; Nucleic Acid Hybridization; Organ Size; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Sheep | 2002 |
Gender-dependent difference in cell calcium handling in VSMC isolated from SHR: the effect of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Enzyme Inhibitors; Extracellular Space; Female; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Sex Characteristics; Thapsigargin; Vasoconstrictor Agents | 2002 |
Possible involvement of aminopeptidase A in hypertension in spontaneously hypertensive rats (SHRs) and change of refractoriness in response to angiotensin II in pregnant SHRs.
Topics: Aminopeptidases; Angiotensin II; Animals; Blood Pressure; Female; Glutamyl Aminopeptidase; Hypertension; Kidney Cortex; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents | 2002 |
Role of endothelin-1 and thromboxane A2 in renal vasoconstriction induced by angiotensin II in diabetes and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Oligopeptides; Oxazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Endothelin; Receptors, Thromboxane A2, Prostaglandin H2; Renal Circulation; Thromboxane A2; Vascular Resistance; Vasoconstriction | 2002 |
Apoptosis, myocardial fibrosis and angiotensin II in the left ventricle of hypertensive rats treated with fosinopril or losartan.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Fibrosis; Fosinopril; Hypertension; Hypertrophy, Left Ventricular; Losartan; Myocardium; Rats; Rats, Inbred SHR | 2002 |
Visualizing tubular lipid peroxidation in intact renal tissue in hypertensive rats.
Topics: Angiotensin II; Animals; Antioxidants; Enzyme Inhibitors; HSP70 Heat-Shock Proteins; Hypertension; Kidney; Kidney Tubules; Lipid Peroxidation; Male; NADPH Oxidases; Nitric Oxide Synthase; Nitroarginine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin E | 2002 |
The role of angiotensin II in hypertension due to adenosine receptors blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Norepinephrine; Potassium Chloride; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Xanthines | 2002 |
Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Body Weight; Coronary Disease; Coronary Vessels; Corticosterone; Cyclooxygenase 2; Diuresis; Drinking; Eating; Eplerenone; Heart; Hypertension; Isoenzymes; Macrophages; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Necrosis; Organ Size; Osteopontin; Potassium; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Renin; Sialoglycoproteins; Sodium; Sodium Chloride; Spironolactone; Vasculitis | 2002 |
The efficacy and tolerability of an angiotensin II receptor blocker, telmisartan, in Thai patients with mild to moderate essential hypertension.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Female; Humans; Hypertension; Male; Middle Aged; Single-Blind Method; Telmisartan; Thailand | 2002 |
Angiotensin II signaling in the brain: compartmentalization of redox signaling?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Brain; Cell Compartmentation; Cholinergic Agonists; Humans; Hypertension; Injections, Intraventricular; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neurons; Oxidation-Reduction; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Signal Transduction; Superoxide Dismutase; Thirst | 2002 |
Target organ damage in hypertension: mechanisms, prevention, and management.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System; Systole | 2002 |
The predominant role of brain angiotensinogen and angiotensin in environmentally induced hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Cold Temperature; Disease Models, Animal; Hypertension; Hypothalamus; Liver; Male; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Time Factors | 2002 |
PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Cell Adhesion Molecules; Cholesterol; Docosahexaenoic Acids; Endothelium, Vascular; Fatty Acids, Nonesterified; Hypertension; In Vitro Techniques; Inflammation; Male; Mesenteric Arteries; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Renin; Transcription Factors; Triglycerides; Vascular Cell Adhesion Molecule-1; Vasodilator Agents | 2002 |
Increase in Cx45 gap junction channels in cerebral smooth muscle cells from SHR.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Brain; Cell Line; Cerebral Arteries; Connexin 43; Connexins; Disease Models, Animal; Enzyme Inhibitors; Female; Femoral Artery; Gap Junctions; Humans; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Patch-Clamp Techniques; Quinine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2002 |
[Clinico-genetic aspects of the hypotensive response and regression of left ventricular hypertrophy in arterial hypertension patients].
Topics: Angiotensin II; Antihypertensive Agents; Cardiomegaly; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Receptors, Angiotensin; Renin-Angiotensin System | 2002 |
Renal nuclear angiotensin II receptors in normal and hypertensive rats.
Topics: Angiotensin II; Animals; Binding Sites; Binding, Competitive; Blood Pressure; Body Weight; Cell Nucleus; Hypertension; Kidney Cortex; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Systole | 2002 |
[Involvement of habenula nucleus in the pathogenesis of stress induced hypertension and the underlying mechanisms].
Topics: Angiotensin II; Animals; Electric Stimulation; Habenula; Hypertension; Neurons; Rats; Saralasin; Stress, Physiological | 1998 |
Urinary angiotensinogen as an indicator of intrarenal Angiotensin status in hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Antibodies; Biomarkers; Blood Pressure; Blotting, Western; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Kidney; Kinetics; Male; Rats; Rats, Sprague-Dawley | 2003 |
Endothelin-1 contributes to the Frank-Starling response in hypertrophic rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Organ Culture Techniques; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger; Stress, Mechanical; Sulfonamides; Tetrazoles | 2003 |
Asymmetry of renal blood flow in patients with moderate to severe hypertension.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Radiography; Radionuclide Imaging; Renal Artery Obstruction; Renal Circulation; Renal Veins; Renin | 2003 |
Renal function and angiotensin AT1 receptor expression in young rats following intrauterine exposure to a maternal low-protein diet.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Diet, Protein-Restricted; Enalapril; Female; Glomerular Filtration Rate; Hypertension; Kidney; Kidney Glomerulus; Male; Maternal Nutritional Physiological Phenomena; Models, Animal; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 2003 |
The serpin protease-nexin 1 is present in rat aortic smooth muscle cells and is upregulated in L-NAME hypertensive rats.
Topics: Administration, Oral; Amyloid beta-Protein Precursor; Angiotensin II; Animals; Aorta; Calcium; Carrier Proteins; Cell Division; Cells, Cultured; Humans; Hypertension; Immunohistochemistry; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Protease Nexins; Rats; Rats, Wistar; Receptors, Cell Surface; Recombinant Proteins; Serpin E2; Serpins; Thrombin; Up-Regulation | 2003 |
How to induce severe electrolyte disturbances in the elderly?
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzothiadiazines; Calcium Channel Blockers; Data Collection; Diuretics; Drug Resistance; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Hypokalemia; Hyponatremia; Male; Middle Aged; Practice Guidelines as Topic; Prognosis; Risk Factors; Sex Factors; Sodium Chloride Symporter Inhibitors; Time Factors | 2002 |
Angiotensin II and renal medullary blood flow in Lyon rats.
Topics: Angiotensin II; Animals; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Hypertension; Indomethacin; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Rats; Rats, Inbred Strains; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, Angiotensin; Reference Values; Renal Circulation; Vasoconstrictor Agents | 2003 |
[Effects of lorsartan, fosinopril on myocardial fibrosis, angiotensin II and cardiac remolding in hypertensive rats].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Fibrosis; Fosinopril; Hypertension; Losartan; Male; Myocardium; Random Allocation; Rats; Rats, Inbred SHR; Ventricular Remodeling | 2001 |
Contribution of endogenous endothelin in the enhanced coronary constriction in DOCA-salt hypertensive rats.
Topics: Angiotensin II; Animals; Coronary Circulation; Desoxycorticosterone; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Heart; Hypertension; In Vitro Techniques; Male; Nephrectomy; Oligopeptides; Propionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride; Vasoconstriction; Vasoconstrictor Agents; Vasopressins | 2003 |
Aminopeptidase activity in renovascular hypertension.
Topics: Aminopeptidases; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Down-Regulation; Heart Atria; Heart Ventricles; Hypertension; Hypertension, Renovascular; Lung; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan | 2003 |
[Zero-stress state of renal artery in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Blood Pressure; Endothelins; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Stress, Mechanical | 2000 |
Leukocyte angiotensin II levels inpatients with essential hypertension:relation to insulin resistance.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Body Mass Index; Chromatography, High Pressure Liquid; Cilazapril; Female; Homeostasis; Humans; Hypertension; Insulin; Insulin Resistance; Leptin; Leukocytes; Male; Middle Aged | 2003 |
Pressor responsiveness to angiotensin in soy-fed spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Caseins; Dose-Response Relationship, Drug; Female; Glycine max; Hypertension; Male; Ovariectomy; Rats; Rats, Inbred SHR | 2002 |
Inhibitors of Na+/Mg2+ exchange activity attenuate the development of hypertension in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Antiporters; Biological Transport; Blood Platelets; Blood Pressure; Body Weight; Cations; Cells, Cultured; Hypertension; Imipramine; Intracellular Membranes; Magnesium; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Quinidine; Rats; Rats, Sprague-Dawley; Sodium; Vasoconstrictor Agents | 2003 |
Proximal tubular fluid angiotensin II levels in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Infusion Pumps; Kidney Tubules, Proximal; Male; Natriuresis; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Renin; Vasoconstrictor Agents | 2003 |
[Clinical study on conducting physical exercise in lowering blood pressure of hypertensive patients and influencing their endocrine hormones].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Captopril; Exercise; Female; Humans; Hypertension; Male; Middle Aged | 2001 |
[Treatment of hypertension: angiotensin-II antagonists potentially better than beta-blockers in the occurrence of cardiovascular and cerebrovascular damage; the LIFE study in perspective].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Cerebrovascular Disorders; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Treatment Outcome | 2003 |
Sympatho-inhibitory actions of irbesartan in pithed spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Decerebrate State; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hypertension; Irbesartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Species Specificity; Sympathetic Nervous System; Sympatholytics; Tetrazoles | 2003 |
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice.
Topics: Angiotensin II; Animals; Calcium Signaling; Cells, Cultured; Heterozygote; Homozygote; Humans; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Phenotype; RGS Proteins; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Mechanism of action of hypotensive prostaglandins in patients with essential hypertension.
Topics: Adult; Alprostadil; Angiotensin II; Animals; Arteries; Dinoprostone; Drug Combinations; Ear; Electric Stimulation; Humans; Hypertension; In Vitro Techniques; Injections, Intravenous; Male; Middle Aged; Norepinephrine; Perfusion; Rabbits; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Cardiac fibrosis occurs early and involves endothelin and AT-1 receptors in hypertension due to endogenous angiotensin II.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Bosentan; Cardiomyopathies; Dansyl Compounds; Disease Models, Animal; Endothelin-1; Fibrosis; Hypertension; Irbesartan; Male; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Sulfonamides; Tetrazoles; Time Factors; Vasoconstrictor Agents | 2003 |
[Angiotensin II contents in plasma, and cardiac and renal tissues of sinoaortic denervated rats].
Topics: Angiotensin II; Animals; Aorta; Autonomic Denervation; Baroreflex; Blood Pressure; Carotid Sinus; Hypertension; Kidney; Male; Myocardium; Rats; Rats, Sprague-Dawley | 2003 |
Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Threonine | 2003 |
Angiotensins in plasma of hypertensive rats and human.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Disease Models, Animal; Enalapril; Humans; Hypertension; Male; Middle Aged; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar | 2003 |
Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Arterioles; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Hypertension; Kidney; Male; Oxygenases; Rats; Rats, Sprague-Dawley; Sodium Chloride; Steroid 16-alpha-Hydroxylase; Vasodilation | 2003 |
Angiotensin II regulation of AT1 and D3 dopamine receptors in renal proximal tubule cells of SHR.
Topics: Angiotensin II; Animals; Antibody Specificity; Cells, Cultured; Hypertension; Immunoblotting; Kidney Tubules, Proximal; Precipitin Tests; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Dopamine D2; Receptors, Dopamine D3 | 2003 |
Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Male; Medulla Oblongata; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sodium Chloride; Tetrazoles; Valine; Valsartan | 2003 |
Sympathetic over activity in the etiology of hypertension of obstructive sleep apnea.
Topics: Angiotensin II; Animals; Catecholamines; Epinephrine; Humans; Hypertension; Microelectrodes; Norepinephrine; Peroneal Nerve; Positive-Pressure Respiration; Sleep Apnea, Obstructive; Sleep, REM; Sympathetic Nervous System; Vasoconstriction; Wakefulness | 2003 |
AT1 receptors in the RVLM mediate pressor responses to emotional stress in rabbits.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Consciousness; Female; Glutamates; Heart Rate; Hypertension; Kidney; Losartan; Male; Medulla Oblongata; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Stress, Psychological; Sympathetic Nervous System; Tetrazoles | 2003 |
Summaries for patients. Effects of blood pressure drugs in patients with diabetes and kidney disease.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Irbesartan; Kidney Failure, Chronic; Male; Middle Aged; Placebos; Risk Factors; Tetrazoles; Treatment Outcome | 2003 |
Mislocalization of eNOS and upregulation of cerebral vascular Ca2+ channel activity in angiotensin-hypertension.
Topics: Angiotensin II; Animals; Blotting, Western; Calcium Channels; Calcium Channels, L-Type; Cerebral Arteries; Enzyme Inhibitors; Female; Fluorescein; Hypertension; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred WKY; Up-Regulation | 2003 |
Chronic angiotensin II inhibition increases levels of calcitonin gene-related peptide mRNA of the dorsal root ganglia in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Calcitonin Gene-Related Peptide; Ganglia, Spinal; Gene Expression; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Tetrazoles; Thiazepines | 2003 |
[Treatment of hypertension: angiotensin-II antagonists potentially better than beta-blockers in the occurrence of cardiovascular and cerebrovascular damage; the LIFE study in perspective].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Practice Guidelines as Topic; Treatment Outcome | 2003 |
Depressor effect induced by dipeptide, Val-Tyr, in hypertensive transgenic mice is due, in part, to the suppression of human circulating renin-angiotensin system.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dipeptides; Humans; Hypertension; Male; Mice; Mice, Transgenic; Renin-Angiotensin System | 2003 |
[Microalbuminuria as a warning sign of diabetic nephropathy. Test your diabetics early!].
Topics: Adolescent; Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzothiadiazines; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Kidney Failure, Chronic; Risk Factors; Smoking Cessation; Sodium Chloride Symporter Inhibitors; Time Factors | 2003 |
[2002--an important year for hypertension! The Danish Society of Hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Receptors, Angiotensin | 2003 |
Expression of the translational repressor NAT1 in experimental models of cardiac hypertrophy.
Topics: Acetyltransferases; Angiotensin II; Animals; Arylamine N-Acetyltransferase; Body Weight; Cardiomegaly; Carrier Proteins; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Hypertension; Isoenzymes; Male; Molecular Weight; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; RNA Processing, Post-Transcriptional | 2003 |
Intracellular signalling pathways regulating vascular NAD(P)H oxidase and hypertension: an opportunity for development of novel antihypertensive agents?
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Enzyme Activation; Enzyme Inhibitors; Humans; Hypertension; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Superoxides; Vasoconstrictor Agents | 2003 |
NAD(P)H oxidase activation by angiotensin II is dependent on p42/44 ERK-MAPK pathway activation in rat's vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Hypertension; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Superoxides; Thioctic Acid; Vasoconstrictor Agents | 2003 |
Increased renal vascular sensitivity to angiotensin II in hypertension is due to decreased response to prostaglandins.
Topics: Adult; Angiotensin II; Blood Pressure; Body Mass Index; Cardiovascular Agents; Diastole; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Indomethacin; Infusions, Intravenous; Kidney; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Regional Blood Flow; Renin; Statistics as Topic; Systole; Vascular Resistance; Vasoconstrictor Agents | 2003 |
Oxygen-15 positron-emission tomography for predicting selective delivery of a chemotherapeutic agent to hepatic cancers during angiotensin II-induced hypertension.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Carcinoma, Hepatocellular; Female; Hepatic Artery; Humans; Hypertension; Liver Circulation; Liver Neoplasms; Male; Middle Aged; Oxygen Radioisotopes; Portal Vein; Spleen; Tomography, Emission-Computed | 2003 |
Up-regulation of vascular and renal mitogen-activated protein kinases in hypertensive rats is normalized by inhibitors of the Na+/Mg2+ exchanger.
Topics: Angiotensin II; Animals; Antiporters; Blood Pressure; Body Weight; Hypertension; Imipramine; Kidney Cortex; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinases; Phosphorylation; Quinidine; Rats; Rats, Sprague-Dawley; Up-Regulation | 2003 |
Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Buthionine Sulfoximine; Cyclic AMP; Cyclic GMP; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; F2-Isoprostanes; Glutathione; Heart Rate; Hypertension; Kidney; Losartan; Male; Models, Cardiovascular; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Thromboxane A2; Treatment Outcome | 2003 |
Enhanced angiotensin-mediated responses in the nucleus tractus solitarii of spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Glutamic Acid; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Solitary Nucleus; Species Specificity; Tetrazoles; Valine; Valsartan | 2003 |
What sets the long-term level of renal sympathetic nerve activity: a role for angiotensin II and baroreflexes?
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Hypertension; Infusion Pumps; Kidney; Rabbits; Sympathetic Nervous System; Time Factors | 2003 |
Imbalance of T-cell subsets in angiotensin II-infused hypertensive rats with kidney injury.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cytokines; Hypertension; Imidazoles; Interferon-gamma; Interleukin-4; Kidney; Male; Nephritis, Interstitial; Olmesartan Medoxomil; Polymerase Chain Reaction; Proteinuria; Rats; Rats, Wistar; RNA, Messenger; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; Tetrazoles | 2003 |
[Hemodynamics and cell membrane effects of angiotensin II receptor antagonists in treatment of hypertension].
Topics: Adenosine Triphosphatases; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Platelets; Calcium; Erythrocytes; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Losartan; Membrane Potentials; Membrane Proteins; Middle Aged; Peptidyl-Dipeptidase A | 2003 |
Effect of AT1 receptor blockade on hepatic redox status in SHR: possible relevance for endothelial function?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Hypertension; Liver; Malondialdehyde; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Phosphoproteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Tetrazoles | 2003 |
Bartter's/Gitelman's syndrome: a model for the relationships between hypertension, angiotensin II, oxidative stress and remodeling.
Topics: Angiotensin II; Bartter Syndrome; Humans; Hypertension; Nitric Oxide; Oxidative Stress; Signal Transduction; Syndrome; Vascular Resistance | 2003 |
Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease.
Topics: Adult; Aged; Angiotensin II; Cells, Cultured; Chymases; Collagen; Diabetes Mellitus; Diabetic Nephropathies; Extracellular Matrix; Glomerular Mesangium; Humans; Hypertension; Immunohistochemistry; Kidney; Kidney Tubules; Leukocytes, Mononuclear; Middle Aged; Myocytes, Smooth Muscle; Peptidyl-Dipeptidase A; Serine Endopeptidases; Up-Regulation | 2003 |
Effect of hyperhomocystinemia and hypertension on endothelial function in methylenetetrahydrofolate reductase-deficient mice.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Biological Availability; Endothelium, Vascular; Hyperhomocysteinemia; Hypertension; In Vitro Techniques; Mesenteric Arteries; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Superoxides; Vasodilation; Xanthine Oxidase | 2003 |
Interactions between angiotensin II and baroreflexes in long-term regulation of renal sympathetic nerve activity.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Hypertension; Kidney; Sympathetic Nervous System; Time Factors | 2003 |
Angiotensin II blockade augments renal cortical microvascular pO2 indicating a novel, potentially renoprotective action.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Enalaprilat; Hypertension; Hypoxia; Kidney Cortex; Male; Microcirculation; Oxygen; Oxygen Consumption; Partial Pressure; Pilot Projects; Porphyrins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles | 2003 |
Control of arterial pressure by angiotensin II and nitric oxide at the onset of diabetes.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Enalapril; Hypertension; Male; Models, Animal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2003 |
Low-dose angiotensin II enhances pressor responses without causing sustained hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Hypertension; Kinetics; Male; Rats; Rats, Sprague-Dawley; Restraint, Physical; Telemetry; Vasoconstrictor Agents | 2003 |
Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antioxidants; Blood Pressure; Creatinine; Cyclic N-Oxides; Cyclosporine; Hypertension; Immunosuppressive Agents; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan | 2003 |
Cardiology patient page. What is an angiotensin converting enzyme inhibitor?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiomegaly; Cardiovascular Diseases; Contraindications; Drug Interactions; Humans; Hypertension; Patient Selection; Vasoconstriction | 2003 |
Attenuated responses to angiotensin II in follitropin receptor knockout mice, a model of menopause-associated hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Collagen; Endothelium, Vascular; Extracellular Matrix; Female; Gonadal Steroid Hormones; Heart Rate; Hypertension; Menopause; Mesenteric Arteries; Mice; Mice, Knockout; NADPH Oxidases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Estrogen; Receptors, FSH; Superoxides | 2003 |
Oxidative stress: does it play a role in the genesis of essential hypertension and hypertension of uraemia?
Topics: Angiotensin II; Animals; Endothelium, Vascular; Humans; Hypertension; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Uremia; Vasoconstrictor Agents | 2003 |
Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases.
Topics: Administration, Oral; Angiotensin II; Animals; Aryl Hydrocarbon Hydroxylases; Blood Pressure; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Hypertension; Kidney; Male; Microcirculation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Chloride; Steroid 16-alpha-Hydroxylase; Up-Regulation | 2003 |
PI3-kinase inhibitors abolish the enhanced chronotropic effects of angiotensin II in spontaneously hypertensive rat brain neurons.
Topics: Action Potentials; Angiotensin II; Animals; Brain; Cells, Cultured; Chronobiology Phenomena; Enzyme Inhibitors; Female; Hypertension; Male; Neurons; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2003 |
Analysis of angiotensin II mediated COX-2 downregulation in angiotensin II- or aldosterone-infused hypertensive rat.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2; Down-Regulation; Hypertension; Isoenzymes; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley | 2003 |
Effects of static magnetic fields on plasma levels of angiotensin II and aldosterone associated with arterial blood pressure in genetically hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Radiation; Electromagnetic Fields; Genetic Predisposition to Disease; Hypertension; Male; Radiation Dosage; Rats | 2003 |
Extracellular superoxide dismutase is a major determinant of nitric oxide bioavailability: in vivo and ex vivo evidence from ecSOD-deficient mice.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Catalase; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Hypertension; Hypertension, Renovascular; In Vitro Techniques; Male; Mice; Mice, Knockout; Nitric Oxide; Nitroprusside; Phenylephrine; Recombinant Proteins; Superoxide Dismutase; Superoxides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2003 |
Hypotensive effect of potentiated antibodies to angiotensin II and AT1 receptors.
Topics: Angiotensin II; Animals; Antibodies; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Rats; Receptor, Angiotensin, Type 1 | 2003 |
Renin-angiotensin system function and blood pressure in adult rats after perinatal salt overload.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Body Weight; Female; Hypertension; Immunohistochemistry; Kidney; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2003 |
Apoptosis and NFkappaB activation are simultaneously induced in renal tubulointerstitium in experimental hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Enzyme Inhibitors; Hypertension; Kidney; Kidney Tubules; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Transcription Factor RelA | 2003 |
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-I-converting enzyme deletion/deletion genotype.
Topics: Adult; Angiotensin I; Angiotensin II; Antihypertensive Agents; Female; Gene Deletion; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Vasoconstrictor Agents | 2003 |
In salt-sensitive hypertension, increased superoxide production is linked to functional upregulation of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Endothelium, Vascular; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Isoprostanes; Proteinuria; Rats; Rats, Inbred Dahl; Sodium Chloride; Superoxides; Tetrazoles; Up-Regulation; Vasodilation | 2003 |
Reactivity of the digital blood vessels to angiotensin II in normotensive and hypertensive subjects.
Topics: Angiotensin Amide; Angiotensin II; Blood Pressure; Cardiovascular System; Fingers; Humans; Hypertension | 1961 |
Metabolism of angiotensin II-I-131 in normotensive and hypertensive human subjects.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension | 1961 |
[Research on the production of angiotensin II (hypertensin II)].
Topics: Angiotensin Amide; Angiotensin II; Humans; Hypertension | 1962 |
Angiotensin II in treatment of hypotensive states.
Topics: Angiotensin II; Humans; Hypertension; Hypotension | 1963 |
Renal tubular effect of val-5-angiotensin II amide in rats.
Topics: Angiotensin II; Animals; Hypertension; Kidney Tubules; Rats; Valine | 1963 |
The enzymatic degradation of various angiotensin II derivatives by serum, plasma or kidney homogenate.
Topics: Aminopeptidases; Angiotensin II; Blood; Humans; Hypertension; Kidney; Peptide Hydrolases | 1963 |
Hemodynamic effect of angiotensin II in minute amounts. Observations on normal subjects at rest and during exercise.
Topics: Angiotensin II; Exercise; Hemodynamics; Humans; Hypertension; Physical Exertion; Rest | 1963 |
Influence of aldosterone and angiotensin II on endotoxin shock in the primate.
Topics: Aldosterone; Angiotensin II; Animals; Endotoxins; Humans; Hypertension; Primates; Shock; Shock, Septic | 1963 |
Angiotensin II in the treatment of shock.
Topics: Angiotensin II; Humans; Hypertension; Norepinephrine; Shock | 1963 |
Angiotensin II degradation by human Cohn plasma fractions.
Topics: Angiotensin II; Blood Proteins; Humans; Hypertension | 1963 |
In vitro degradation of I-131 labeled angiotensin II by normotensive and hypertensive human serum.
Topics: Angiotensin Amide; Angiotensin II; Blood Pressure; Hypertension; In Vitro Techniques; Iodine | 1962 |
Metabolism and distribution of I-131-labeled angiotensin II.
Topics: Angiotensin Amide; Angiotensin II; Hypertension; Iodine; Radioisotopes | 1962 |
The effect of catecholamines, corticosteroids and angiotensin II on the heart-lung preparation of the dog.
Topics: Adrenal Cortex Hormones; Angiotensin II; Animals; Cardiovascular Agents; Catecholamines; Desoxycorticosterone; Dogs; Epinephrine; Heart; Hypertension; Norepinephrine | 1962 |
Effect of angiotensin II on adrenal ascorbic acid.
Topics: Adrenal Glands; Angiotensin II; Ascorbic Acid; Humans; Hypertension | 1962 |
Acute hemodynamic effects of angiotensin II. Preliminary report.
Topics: Angiotensin II; Cardiac Catheterization; Cardiac Output; Cyanosis; Heart Septal Defects, Ventricular; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Lung | 1963 |
Angiotensin II, digital blood flow, and the precapillary and postcapillary blood vessels of man.
Topics: Angiotensin II; Blood Flow Velocity; Blood Vessels; Hemodynamics; Hypertension; Norepinephrine | 1963 |
Increased susceptibility to pyelonephritis during acute hypertension by angiotensin II and norepinephrine.
Topics: Angiotensin II; Disease Susceptibility; Escherichia coli Infections; Humans; Hypertension; Norepinephrine; Pyelonephritis | 1963 |
Angiotensin pressor inhibition by aldosterone in the rabbit.
Topics: Aldosterone; Angiotensin II; Angiotensins; Animals; Blood Pressure; Hypertension; Rabbits; Renin | 1963 |
Angiotensin II: its metabolic fate.
Topics: Adrenal Glands; Angiotensin II; Female; Humans; Hypertension; Kidney | 1962 |
RECENT STUDIES ON I-131-LABELLED ANGIOTENSIN II AND ANALOGUES.
Topics: Angiotensin II; Angiotensins; Blood Chemical Analysis; Electrophoresis; Hypertension; Iodine; Iodine Isotopes; Metabolism; Peptides; Salivary Glands; Sympathectomy | 1964 |
HYPERRESPONSIVENESS OF RENAL HYPERTENSIVE RATS TO INTRAVENOUS ANGIOTENSIN II.
Topics: Angiotensin II; Angiotensins; Biological Assay; Blood Pressure; Blood Pressure Determination; Hypertension; Hypertension, Renal; Kidney; Nephrectomy; Pharmacology; Rats; Research | 1964 |
A METHOD FOR DETERMINATION OF ANGIOTENSIN II IN HUMAN BLOOD.
Topics: Angiotensin II; Angiotensins; Biological Assay; Blood Chemical Analysis; Blood Pressure Determination; Hypertension; Hypertension, Renal; Kidney; Rats | 1964 |
ACUTE INFUSION OF SYNTHETIC ANGIOTENSIN II IN PATIENTS WITH ESSENTIAL HYPERTENSION. ITS EFFECT ON RENAL HEMODYNAMICS AND ON ELECTROLYTE AND WATER EXCRETION.
Topics: Angiotensin II; Angiotensins; Biomedical Research; Blood Pressure; Electrolytes; Essential Hypertension; Humans; Hypertension; Inulin; Kidney; Kidney Function Tests; Kidney Tubules; Natriuresis; p-Aminohippuric Acid; Physiology; Water; Water-Electrolyte Balance | 1964 |
THE EFFECT OF ANGIOTENSIN II ON THE BLOOD PRESSURE IN HUMANS WITH HYPERTENSIVE DISEASE.
Topics: Acidosis; Angiotensin II; Angiotensins; Aortic Coarctation; Biomedical Research; Blood Pressure; Glomerulonephritis; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Infusions, Parenteral; Kidney; Kidney Diseases; Liver Cirrhosis; Norepinephrine; Pharmacology; Sodium Chloride | 1964 |
[THE EFFECT OF COMBINED INFUSION OF L-NORADRENALINE AND ANGIOTENSIN II ON THE RENAL WATER-ELECTROLYTE EXCRETION IN NORMAL PERSONS. CONTRIBUTION TO THE MECHANISM OF ACTION OF ANGIOTENSIN IN HYPERTENSION].
Topics: Angiotensin II; Angiotensins; Electrolytes; Hypertension; Injections, Intravenous; Kidney; Norepinephrine; Pharmacology; Urine; Water; Water-Electrolyte Balance | 1965 |
PROLONGED INFUSIONS OF ANGIOTENSIN II AND NOREPINEPHRINE AND BLOOD PRESSURE, ELECTROLYTE BALANCE, AND ALDOSTERONE AND CORTISOL SECRETION IN NORMAL MAN AND IN CIRRHOSIS WITH ASCITES.
Topics: Aldosterone; Angiotensin II; Angiotensins; Ascites; Blood Pressure; Body Fluids; Dexamethasone; Humans; Hydrocortisone; Hypertension; Liver Cirrhosis; Male; Metabolism; Natriuresis; Norepinephrine; Pharmacology; Potassium; Sodium; Sodium, Dietary; Tachyphylaxis; Urine; Water-Electrolyte Balance | 1965 |
Hypotensive agents and pressor substances. The effect of epinephrine, norepinephrine, angiotensin II, and others on the secretory rate of aldosterone in man.
Topics: Aldosterone; Angiotensin Amide; Angiotensin II; Antihypertensive Agents; Catecholamines; Epinephrine; Hypertension; Norepinephrine; Secretory Rate; Vasoconstrictor Agents | 1960 |
Hormones and the pathogenesis of congestive heart failure: vasopressin, aldosterone, and angiotensin II. Further evidence for renal-adrenal interaction from studies in hypertension and in cirrhosis.
Topics: Aldosterone; Angiotensin Amide; Angiotensin II; Heart Defects, Congenital; Heart Failure; Humans; Hypertension; Kidney; Vasopressins | 1962 |
Angiotensin II studies in hypertension.
Topics: Angiotensin Amide; Angiotensin II; Hypertension; Research | 1962 |
Subfornical organ-angiotensin II pressor system takes part in pressor response of emotional circuit.
Topics: Amygdala; Angiotensin II; Animals; Blood Pressure; Brain; Glutamic Acid; Heart Rate; Histocytochemistry; Hypertension; Hypothalamic Area, Lateral; Intralaminar Thalamic Nuclei; Male; Microinjections; Models, Neurological; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Stress, Psychological; Subfornical Organ | 2003 |
Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Cardiomegaly; Cell Movement; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Intracellular Signaling Peptides and Proteins; Macrophages; Male; NADPH Oxidases; Organ Culture Techniques; Protein Serine-Threonine Kinases; Rats; Rats, Inbred WKY; rho-Associated Kinases; Superoxides; Vasoconstrictor Agents; Vasodilation | 2003 |
Prevalence and role of a raised aldosterone to renin ratio in the diagnosis of primary aldosteronism: a debate on the scientific logic of the use of the ratio in practice.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Diagnosis, Differential; Diagnostic Tests, Routine; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Renin | 2003 |
Angiotensin-converting enzyme inhibitors: optimal management of cardiovascular risk.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cardiovascular Diseases; Diabetic Nephropathies; Evidence-Based Medicine; Humans; Hypertension; Losartan; Risk Management; Treatment Outcome | 2003 |
Protective effects of the angiotensin II type 1 (AT1) receptor blockade in low-renin deoxycorticosterone acetate (DOCA)-treated spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cardiomegaly; Desoxycorticosterone; Endothelins; Hypertension; Isoprostanes; Kidney; Losartan; Male; Malondialdehyde; Proteinuria; Rats; Rats, Inbred SHR; Renin | 2004 |
Genetic determinants of nonmodulating hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Epistasis, Genetic; Family Health; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Quantitative Trait Loci; Renin-Angiotensin System; Sex Factors | 2003 |
Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Bacterial Proteins; Blood Pressure; Cardiomegaly; Constriction, Pathologic; Disease Models, Animal; Disease Progression; Hypertension; Isoenzymes; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Myocardium; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species | 2003 |
Hypotensive function of the brain angiotensin-(1-7) in Sprague Dawley and renin transgenic rats.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cerebral Ventricles; Cerebrospinal Fluid; Heart Rate; Hemorrhage; Hypertension; Hypotension; Hypothalamus; Injections, Intraventricular; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Shock, Hemorrhagic; Species Specificity | 2003 |
Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomyopathy, Hypertrophic; Fibroblast Growth Factor 1; Gene Expression Regulation; Genes, fos; Heart Rate; Hypertension; Imidazoles; Infusion Pumps, Implantable; Losartan; Male; Natriuretic Peptide, Brain; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Vascular Endothelial Growth Factor A | 2003 |
Serial analysis of gene expression in mouse kidney following angiotensin II administration.
Topics: Angiotensin II; Animals; Gene Expression Profiling; Gene Expression Regulation; Gene Library; Genome; Genomics; Hypertension; Kidney; Male; Mice; Mice, Inbred Strains; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
[Dosage equivalents of AT1-receptor antagonists available in Germany].
Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan | 2003 |
Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and Angiotensin neuromodulation.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Adult; Angiotensin II; Biological Transport; Desipramine; Female; Humans; Hypertension; Male; Neurons; Norepinephrine; Sympathetic Nervous System | 2004 |
Human adipocytes secrete mineralocorticoid-releasing factors.
Topics: Adipocytes; Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Base Sequence; Colforsin; Culture Media, Conditioned; Female; Hot Temperature; Humans; Hypertension; In Vitro Techniques; Mineralocorticoids; Models, Biological; Obesity; Phosphoproteins; RNA, Messenger | 2003 |
ROS during the acute phase of Ang II hypertension participates in cardiovascular MAPK activation but not vasoconstriction.
Topics: Acute Disease; Adrenergic alpha-Agonists; Angiotensin II; Animals; Antioxidants; Aorta; Benzimidazoles; Biphenyl Compounds; Cyclic N-Oxides; Enzyme Activation; Heart Ventricles; Hemodynamics; Hypertension; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Tetrazoles; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents | 2004 |
Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomarkers; Captopril; Disease Models, Animal; Echocardiography; Endothelin-1; Genetic Markers; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Receptors, Aryl Hydrocarbon; RNA, Messenger; Ventricular Myosins | 2003 |
Alternative splicing of cGMP-dependent protein kinase I and nitrate tolerance.
Topics: Alternative Splicing; Angiotensin II; Animals; Basilar Artery; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; DNA, Complementary; Drug Tolerance; Hypertension; Introns; Isoenzymes; Muscle, Smooth, Vascular; Nitrates; Rats; Reproducibility of Results; RNA, Messenger | 2003 |
Entacapone protects from angiotensin II-induced inflammation and renal injury.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Blood Pressure; Cardiomegaly; Catechol O-Methyltransferase; Catechols; Creatinine; Dinoprost; Disease Models, Animal; Dopamine; Enzyme Inhibitors; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; Leukocytes; Male; Models, Cardiovascular; Nitriles; Norepinephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2003 |
Chronic administration of losartan reverses cardiovascular changes in hypertensive fructose-fed rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Endothelium; Fructose; Hypertension; Losartan; Male; Microvascular Angina; Nitric Oxide; Nitric Oxide Synthase; Rats; Receptor, Angiotensin, Type 2 | 2003 |
Hypersensitivity of the adrenal cortex to trophic and secretory effects of angiotensin II in Lyon genetically-hypertensive rats.
Topics: Adrenal Cortex; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Hypertension; Male; Organ Size; Rats; Rats, Mutant Strains; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2004 |
Stenosis progression after surgical injury in Milan hypertensive rat carotid arteries.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Carotid Arteries; Carotid Stenosis; Disease Progression; Gene Expression; Genes, fos; Genes, jun; Genes, myc; Hypertension; Models, Animal; Rats; Rats, Inbred Strains; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger | 2003 |
SAM68: a downstream target of angiotensin II signaling in vascular smooth muscle cells in genetic hypertension.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; Enzyme Inhibitors; Hypertension; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligonucleotides, Antisense; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Poly U; Protein Isoforms; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA-Binding Proteins; Signal Transduction; Tissue Distribution | 2004 |
Pressure-independent effects of angiotensin II on hypertensive myocardial fibrosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Movement; Constriction; Coronary Vessels; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Inflammation; Macrophages; Male; Myocardium; Peptidyl-Dipeptidase A; Pressure; Rats; Rats, Wistar; Tetrazoles | 2004 |
Ganglionic action of angiotensin contributes to sympathetic activity in renin-angiotensinogen transgenic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Pressure; Chlorisondamine; Ganglia, Sympathetic; Ganglionic Blockers; Humans; Hypertension; Kidney; Losartan; Mice; Mice, Transgenic; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 2004 |
Enhanced oxidative stress and impaired thioredoxin expression in spontaneously hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II; Animals; Blotting, Western; Deoxyguanosine; Disease Models, Animal; Gene Expression Regulation; Hypertension; Immunohistochemistry; Monocytes; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thioredoxins | 2004 |
Changes of central norepinephrine, beta-endorphin, LEU-enkephalin, peripheral arginine-vasopressin, and angiotensin II levels in acute and chronic phases of sino-aortic denervation in rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Baroreflex; beta-Endorphin; Blood Pressure; Brain; Chronic Disease; Denervation; Enkephalin, Leucine; Heart Rate; Hypertension; Male; Norepinephrine; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Sinoatrial Node | 2004 |
Role for thromboxane receptors in angiotensin-II-induced hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cyclooxygenase 1; Heart; Heart Rate; Hypertension; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Prostaglandin-Endoperoxide Synthases; Receptors, Thromboxane A2, Prostaglandin H2; Survival Analysis | 2004 |
Early pathophysiological changes in cerebral vessels predisposing to stroke.
Topics: Amlodipine; Angiotensin II; Animals; Arterioles; Benzylamines; Brain; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; CREB-Binding Protein; Disease Susceptibility; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Hyperplasia; Hypertension; Models, Animal; Muscle, Smooth, Vascular; Nicotine; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nuclear Proteins; Oxidative Stress; Proliferating Cell Nuclear Antigen; Rats; Stroke; Sulfonamides; Trans-Activators | 2003 |
Gender differences in superoxide generation in microvessels of hypertensive rats: role of NAD(P)H-oxidase.
Topics: Actins; Angiotensin II; Animals; Arterioles; Endothelium, Vascular; Female; Gender Identity; Hypertension; Male; Microscopy, Fluorescence; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Superoxides | 2004 |
Decrease in hypothalamic gamma adducin in rat models of hypertension.
Topics: Angiotensin II; Animals; Calmodulin-Binding Proteins; Cells, Cultured; Hypertension; Hypothalamus; Male; Neurons; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley | 2004 |
Alterations in sympathetic ganglionic transmission in response to angiotensin II in (mRen2)27 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Autoradiography; Ganglia, Sympathetic; Hypertension; Mice; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Synaptic Transmission | 2004 |
Endogenous angiotensin and pressure modulate brain angiotensinogen and AT1A mRNA expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Pressure; Brain Stem; Gene Expression; Hypertension; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Solitary Nucleus | 2004 |
[Microalbuminuria is an early marker for increased morbidity and mortality].
Topics: Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension; Losartan; Male; Meta-Analysis as Topic; Prevalence; Proteinuria; Renin-Angiotensin System; Risk Factors; Stroke | 2003 |
Angiotensin II induced upregulation of G alpha q/11, phospholipase C beta 3 and extracellular signal-regulated kinase 1/2 via angiotensin II type 1 receptor.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Isoenzymes; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Phospholipase C beta; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Signal Transduction; Type C Phospholipases; Up-Regulation | 2004 |
Angiotensin-(1-7) modulates vascular resistance and sympathetic neurotransmission in kidneys of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Kidney; Male; Norepinephrine; Organ Culture Techniques; Peptide Fragments; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Stimulation, Chemical; Sympathetic Nervous System; Vascular Resistance | 2004 |
A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Arachidonic Acid; Blotting, Western; Chromatography, Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Fenofibrate; Humans; Hypertension; Hypolipidemic Agents; Immunohistochemistry; Kidney; Kidney Diseases; Mass Spectrometry; NF-kappa B; Polymerase Chain Reaction; Rats; Receptors, Cytoplasmic and Nuclear; Renin; Transcription Factors; Vasoconstrictor Agents | 2004 |
Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats.
Topics: Amlodipine; Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Endothelium-Dependent Relaxing Factors; Heart Ventricles; Hypertension; Isoprostanes; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, LDL; Receptors, Oxidized LDL; Scavenger Receptors, Class E | 2004 |
Adrenomedullin modulates hemodynamic and cardiac effects of angiotensin II in conscious rats.
Topics: Adrenomedullin; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body Weight; Echocardiography; Heart; Heart Rate; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Norepinephrine; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Proteins; Receptor, Angiotensin, Type 1; Receptors, Adrenomedullin; Receptors, Peptide; Reverse Transcriptase Polymerase Chain Reaction; Telemetry; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Selective increase in renal arcuate innervation density and neurogenic constriction in chronic angiotensin II-infused rats.
Topics: Angiotensin II; Animals; Axons; Endothelium, Vascular; Hypertension; Infusions, Intravenous; Kidney; Male; Mesenteric Arteries; Muscle, Smooth; Phenylephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Sympathetic Nervous System; Vasoconstriction; Vasodilation | 2004 |
Hypertension, angiotensin, and stroke: beyond blood pressure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cerebrovascular Circulation; Humans; Hypertension; Renin-Angiotensin System; Risk Factors; Signal Transduction; Stroke | 2004 |
Angiotensin-(1-7) inhibits the angiotensin II-enhanced norepinephrine release in coarcted hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Bradykinin; Hypertension; Hypothalamus; Imidazoles; In Vitro Techniques; Nitric Oxide; Norepinephrine; Peptide Fragments; Potassium; Pyridines; Rats; Rats, Wistar | 2004 |
Ethnic, geographic and dietary influences upon vasoactive hormones and blood pressure among Greenland Inuit and Danes.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Denmark; Epidemiologic Studies; Ethnicity; Feeding Behavior; Female; Greenland; Humans; Hypertension; Inuit; Male; Natriuretic Peptides; Potassium; Renin-Angiotensin System; Sodium; Topography, Medical; Vasopressins | 2003 |
Angiotensin II influences ovarian follicle development in the transgenic (mRen-2)27 and Sprague-Dawley rat.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Female; Hypertension; Immunohistochemistry; In Situ Hybridization; Litter Size; Ovarian Follicle; Peptidyl-Dipeptidase A; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger | 2004 |
Sub-depressor dose of angiotensin type-1 receptor blocker inhibits transforming growth factor-beta-mediated perivascular fibrosis in hypertensive rat hearts.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Collagen; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; Endomyocardial Fibrosis; Fibroblasts; Hypertension; Male; Myocytes, Cardiac; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Transforming Growth Factor beta; Ventricular Remodeling | 2003 |
PPAR alpha activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats.
Topics: Angiotensin II; Animals; Blood Pressure; Collagen; Electrocardiography; Fenofibrate; Fibrosis; Heart; Hypertension; Inflammation; Infusions, Intravenous; Intercellular Adhesion Molecule-1; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
How does angiotensin II cause renal injury?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Disease Progression; Humans; Hypertension; Hypertension, Renal; Kidney Diseases; Kidney Glomerulus; Models, Biological; Peptidyl-Dipeptidase A; Rats; Renal Circulation; Renal Insufficiency; Renin-Angiotensin System; Vasoconstriction | 2004 |
From inflammation to fibrosis: a stiff stretch of highway.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Apoptosis; Cell Adhesion Molecules; Collagen; Coronary Vessels; Cytokines; Fibroblasts; Fibrosis; Humans; Hypertension; Inflammation; Ligation; Macrophages; Myocardium; Myocytes, Cardiac; Necrosis; Oxidative Stress; Rats | 2004 |
Role of pressure in angiotensin II-induced renal injury: chronic servo-control of renal perfusion pressure in rats.
Topics: Angiotensin II; Animals; Aortic Valve Stenosis; Blood Pressure; Carotid Arteries; Femoral Artery; Fibrosis; Hypertension; Kidney; Kidney Tubular Necrosis, Acute; Male; NF-kappa B; Pressure; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium Chloride, Dietary; Transforming Growth Factor beta | 2004 |
Effect of propofol on vasoconstriction and calcium mobilization induced by Angiotensin II differs in aortas from normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium; Dose-Response Relationship, Drug; Hypertension; Hypnotics and Sedatives; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth, Vascular; Propofol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Relationship between hypertensive left ventricular hypertrophy, neurohormonal factors and ventricular arrhythmias in very old patients.
Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Arrhythmias, Cardiac; Biomarkers; Coronary Angiography; Echocardiography; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Insulin; Male; Neurotransmitter Agents; Renin | 2004 |
AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Hypertension; Imidazoles; Kidney; Kidney Tubules, Proximal; Male; Olmesartan Medoxomil; Proteinuria; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Tetrazoles | 2004 |
Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Bone Marrow Transplantation; Chemokine CCL2; Chemotaxis, Leukocyte; Enzyme Inhibitors; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Inflammation; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Monocytes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Olmesartan Medoxomil; Pilot Projects; Radiation Chimera; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, CCR2; Receptors, Chemokine; Recombinant Fusion Proteins; Superoxide Dismutase; Tetrazoles; Up-Regulation | 2004 |
Role of brain and peripheral angiotensin II in hypertension and altered arterial baroreflex programmed during fetal life in rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Blood Pressure; Brain; Dietary Proteins; Enalaprilat; Female; Fetus; Hypertension; Male; Pregnancy; Protein Deficiency; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2004 |
Angiotensin-(1-7) antagonist A-779 attenuates the potentiation of bradykinin by captopril in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Captopril; Drug Synergism; Hypertension; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Peptide Fragments; Rats; Rats, Wistar | 2004 |
Role of NAD(P)H oxidase on vascular alterations in angiotensin II-infused mice.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Body Weight; Collagen; Endothelium, Vascular; Enzyme Inhibitors; Hydralazine; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred BALB C; NADPH Oxidases; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Eprosartan improves cardiac performance, reduces cardiac hypertrophy and mortality and downregulates myocardial monocyte chemoattractant protein-1 and inflammation in hypertensive heart disease.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Chemokine CCL2; Down-Regulation; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Immunohistochemistry; Macrophages; Myocardial Contraction; Myocardium; Rats; Rats, Inbred SHR; RNA, Messenger; Thiophenes; Ultrasonography; Vasculitis | 2004 |
Peri-implantation undernutrition programs blunted angiotensin II evoked baroreflex responses in young adult sheep.
Topics: Angiotensin II; Animals; Baroreflex; Birth Weight; Blastocyst; Blood Pressure; Female; Food Deprivation; Hemodynamics; Hypertension; Hypotension; Malnutrition; Nitroprusside; Organ Size; Phenylephrine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Reflex, Abnormal; Sheep; Tachycardia; Vasodilator Agents | 2004 |
Aldosterone antagonist facilitates the cardioprotective effects of angiotensin receptor blockers in hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Cardiomegaly; Cardiotonic Agents; Collagen Type I; Collagen Type III; Drug Synergism; Fibrosis; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Spironolactone; Tetrazoles | 2004 |
Fingernail clubbing and chromonychia associated with the use of angiotensin II receptor blockers.
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Fingers; Humans; Hypertension; Losartan; Male; Nail Diseases; Toes | 2004 |
Relationship between the tooth eruption and regional blood flow in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Incisor; Male; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Regional Blood Flow; Tooth Eruption; Tooth Mobility; Vasoconstrictor Agents | 2004 |
Increased renovascular response to angiotensin II in persons genetically predisposed to arterial hypertension disappears after chronic angiotensin-converting enzyme inhibition.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Pressure; Diastole; Dose-Response Relationship, Drug; Genetic Predisposition to Disease; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Reference Values; Regional Blood Flow; Renin; Systole; Time Factors; Treatment Outcome; Vascular Resistance; Vasoconstrictor Agents | 2004 |
Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Allosteric Regulation; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Calcium Signaling; CHO Cells; Cricetinae; Cricetulus; Gene Expression; Genes, Synthetic; Glial Fibrillary Acidic Protein; Globins; Humans; Hypertension; Imidazoles; Mice; Mice, Transgenic; Organ Specificity; Protein Sorting Signals; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Renin; Renin-Angiotensin System; Tetrazoles; Transgenes | 2004 |
Tooth loss is associated with an increased risk of hypertension in postmenopausal women.
Topics: Adult; Aged; Angiotensin II; Body Mass Index; Comorbidity; Cross-Sectional Studies; Female; Hemodynamics; Humans; Hypertension; Japan; Lipids; Middle Aged; Peptidyl-Dipeptidase A; Postmenopause; Renin; Risk Factors; Tooth Loss | 2004 |
Elevated blood pressure in normotensive rats produced by 'knockdown' of the angiotensin type 2 receptor.
Topics: Angiotensin II; Animals; Blood Pressure; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Female; Hypertension; Male; Mice; PC12 Cells; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2 | 2004 |
Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Valve Stenosis; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Hypertension; Imidazoles; Ligation; Losartan; Male; Mice; Mice, Inbred ICR; Models, Animal; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; RNA, Messenger; Up-Regulation; Vasoconstriction | 2004 |
G protein alpha(i2): a potential link between hypertension and insulin resistance?
Topics: Adult; Angiotensin II; Calcium; Cells, Cultured; Female; Fibroblasts; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; RNA, Messenger; Skin; Vasoconstrictor Agents | 2004 |
Aspirin, superoxide anions and development of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Aspirin; Cells, Cultured; Hypertension; Losartan; Luminescent Measurements; Male; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Time Factors; Vasoconstrictor Agents | 2004 |
Abnormal regulation of G protein alpha(i2) subunit in skin fibroblasts from insulin-resistant hypertensive individuals.
Topics: Adult; Angiotensin II; Calcium; Cells, Cultured; Culture Media, Serum-Free; Fasting; Female; Fibroblasts; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; RNA, Messenger; Skin; Vasoconstrictor Agents | 2004 |
Prevention of angiotensin II-induced hypertension, cardiovascular hypertrophy and oxidative stress by acetylsalicylic acid in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Aspirin; Body Weight; Cells, Cultured; Hypertension; Hypertrophy, Left Ventricular; Losartan; Luminescent Measurements; Male; Muscle, Smooth, Vascular; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Time Factors; Vasoconstrictor Agents | 2004 |
Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Therapy, Combination; Homeostasis; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reserpine; Tetrazoles; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Plasma and kidney angiotensin II levels and renal functional responses to AT(1) receptor blockade in hypertensive Ren-2 transgenic rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Glomerular Filtration Rate; Hypertension; Kidney Function Tests; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Plasma Flow; RNA, Messenger; Sodium; Tetrazoles | 2004 |
RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Cells, Cultured; Cyclic AMP; Cyclic GMP; Hypertension; Muscle, Smooth, Vascular; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Stroke; Tetrazoles; Valine; Valsartan | 2004 |
Cyclin-dependent kinase inhibitor, p21Waf1, regulates vascular smooth muscle cell hypertrophy.
Topics: Adenoviridae; Angiotensin II; Animals; Aorta, Thoracic; Blood Proteins; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Fetal Proteins; Gene Transfer Techniques; Hyperplasia; Hypertension; Hypertrophy; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tumor Suppressor Proteins; Vasoconstrictor Agents | 2004 |
Vascular synthesis of aldosterone: role in hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Cardiomegaly; Cytochrome P-450 CYP11B2; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Sodium Chloride; Species Specificity | 2004 |
Marinobufagenin may mediate the impact of salty diets on left ventricular hypertrophy by disrupting the protective function of coronary microvascular endothelium.
Topics: Angiotensin II; Animals; Blood Pressure; Bufanolides; Endothelium, Vascular; Humans; Hypertension; Hypertrophy, Left Ventricular; Microcirculation; Models, Biological; Models, Theoretical; Nitric Oxide; Sodium Chloride, Dietary; Vasoconstrictor Agents | 2004 |
A lower ratio of AT1/AT2 receptors of angiotensin II is found in female than in male spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Estrogens; Estrus; Female; Gene Expression; Hypertension; In Vitro Techniques; Kidney; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Ovariectomy; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics; Vascular Resistance | 2004 |
Tempol attenuates excitatory actions of angiotensin II in the rostral ventrolateral medulla during emotional stress.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Brain; Cardiovascular Physiological Phenomena; Cyclic N-Oxides; Free Radical Scavengers; Hemodynamics; Hypertension; Nitric Oxide; Rabbits; Spin Labels; Stress, Physiological; Stress, Psychological; Superoxides; Sympathetic Nervous System | 2004 |
Pathogenesis of structural vascular changes in hypertension.
Topics: Angiotensin II; Animals; Blood Vessels; Humans; Hypertension; Vascular Resistance | 2004 |
The dietary sodium-blood pressure plot "stiffens".
Topics: Angiotensin II; Blood Pressure; Endothelium, Vascular; Humans; Hypertension; Sodium-Potassium-Exchanging ATPase; Sodium, Dietary; Vascular Resistance | 2004 |
Hypertension caused by angiotensin II infusion involves increased superoxide production in the central nervous system.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Brain Chemistry; Cardiomegaly; Genetic Therapy; Genetic Vectors; Humans; Hypertension; Infusion Pumps, Implantable; Infusions, Parenteral; Injections, Intraventricular; Isoenzymes; Losartan; Mice; Mice, Inbred C57BL; Myocardium; Organ Size; Oxidation-Reduction; Oxidative Stress; Recombinant Fusion Proteins; Subfornical Organ; Superoxide Dismutase; Superoxides | 2004 |
Influence of the 4G/5G PAI-1 genotype on angiotensin II-stimulated human endothelial cells and in patients with hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Case-Control Studies; Cells, Cultured; Endothelial Cells; Female; Fibrinolysis; Genetic Markers; Genotype; Humans; Hypertension; Losartan; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric; Stimulation, Chemical | 2004 |
The upregulation of ICAM-1 and P-selectin requires high blood pressure but not circulating renin-angiotensin system in vivo.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cell Adhesion; Disease Models, Animal; Endothelium, Vascular; Hypertension; Intercellular Adhesion Molecule-1; Macrophages; Male; Monocytes; NF-kappa B; P-Selectin; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Transcription Factor RelA; Up-Regulation | 2004 |
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.
Topics: Acetophenones; Acetylcholine; Alkaloids; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Benzophenanthridines; Captopril; Enzyme Inhibitors; Hypertension; Male; Models, Biological; NADPH Oxidases; Nitric Oxide Donors; Nitric Oxide Synthase; Onium Compounds; Organ Culture Techniques; Oxidative Stress; Penicillamine; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Renin-Angiotensin System; Staurosporine; Superoxide Dismutase; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Hypertension; Immunohistochemistry; Kidney Tubules; Kidney Tubules, Collecting; Male; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renin | 2004 |
Effects of angiotensin II and insulin on ERK1/2 activation in fibroblasts from hypertensive patients.
Topics: Adult; Angiotensin II; Biomarkers; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fibroblasts; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Italy; Male; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotransferases; Receptor, Angiotensin, Type 1; Time Factors; Treatment Outcome; Vasoconstrictor Agents | 2004 |
The renin angiotensin system in childhood hypertension: selective increase of angiotensin-(1-7) in essential hypertension.
Topics: Adolescent; Angiotensin I; Angiotensin II; Calcium Channel Blockers; Case-Control Studies; Child; Child, Preschool; Female; Humans; Hypertension; Male; Peptide Fragments; Renin; Renin-Angiotensin System | 2004 |
Effects of angiotensin II type 1 receptor antagonist on pressor responses to pulsatile compression of the rostral ventrolateral medulla in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypertension; Imidazoles; Injections, Intravenous; Kynurenic Acid; Male; Medulla Oblongata; Pulsatile Flow; Pyridines; Rats; Rats, Wistar; Sympathetic Nervous System; Tetrazoles; Vasoconstrictor Agents | 2004 |
Is vascular endothelial growth factor a missing link between hypertension and inflammation?
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Extracellular Matrix Proteins; Genes, Lethal; Humans; Hypertension; Inflammation; Metabolic Syndrome; Mice; Mice, Knockout; Mice, Transgenic; Muscle, Skeletal; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Rats; Transfection; Transgenes; Vascular Endothelial Growth Factor A | 2004 |
Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Electrophoretic Mobility Shift Assay; Heat-Shock Response; Hot Temperature; HSP70 Heat-Shock Proteins; Hydralazine; Hypertension; Imidazoles; Inflammation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; NF-kappa B; NF-kappa B p50 Subunit; Norepinephrine; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Thiophenes; Transcription Factor RelA | 2004 |
And what about the endothelium? On the predominance of cerebral superoxide formation for angiotensin II-induced systemic hypertension.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Genetic Therapy; Humans; Hypertension; Mice; Models, Biological; Neurons; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Recombinant Fusion Proteins; Research Design; Species Specificity; Subfornical Organ; Superoxide Dismutase; Superoxides | 2004 |
Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Cardiac Output, Low; Cardiomyopathies; Collagenases; Disease Progression; Enzyme Precursors; Extracellular Matrix; Gelatinases; Gene Expression; Gene Expression Profiling; Genetic Predisposition to Disease; Heart Rupture; Humans; Hypertension; Hypertrophy, Left Ventricular; Matrix Metalloproteinase 9; Metalloendopeptidases; Mice; Mice, Knockout; Myocardium; Rats; Rats, Sprague-Dawley; Renin; Stroke Volume; Thrombospondins; Up-Regulation | 2004 |
Hypertensive response to acute stress is attenuated in interleukin-6 knockout mice.
Topics: Acute Disease; Adrenergic alpha-Agonists; Angiotensin II; Animals; Blood Pressure; Heart Rate; Housing, Animal; Hypertension; Inflammation; Interleukin-6; Male; Mesenteric Arteries; Mice; Mice, Knockout; Motor Activity; Norepinephrine; Phenylephrine; Renin; Renin-Angiotensin System; Stress, Psychological; Sympathetic Nervous System; Telemetry; Territoriality | 2004 |
Increased expression of regulator of G protein signaling-2 (RGS-2) in Bartter's/Gitelman's syndrome. A role in the control of vascular tone and implication for hypertension.
Topics: Adult; Angiotensin II; Bartter Syndrome; Case-Control Studies; Cohort Studies; Creatinine; Cyclic GMP; Female; Gene Expression; Humans; Hypertension; Middle Aged; Monocytes; Nitrates; Nitrites; RGS Proteins; RNA, Messenger; Vasomotor System | 2004 |
Hypertension: a novel regulator of adaptive immunity in atherosclerosis?
Topics: Adaptation, Physiological; Angiotensin II; Animals; Apolipoproteins E; Arteriosclerosis; Collagen; Disease Models, Animal; Fibrosis; Humans; Hypertension; Hypertension, Renovascular; Inflammation; Ligation; Lipids; Macrophages; Mice; Nephrectomy; Phenotype; Rabbits; Renal Artery; Renin-Angiotensin System; Th1 Cells; Th2 Cells | 2004 |
Peroxisome proliferator-activated receptor gamma ligands inhibit Rho/Rho kinase pathway by inducing protein tyrosine phosphatase SHP-2.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Cycle Proteins; Cells, Cultured; Chromans; Hypertension; Intracellular Signaling Peptides and Proteins; Ligands; Male; Muscle, Smooth, Vascular; Pioglitazone; Platelet-Derived Growth Factor; PPAR gamma; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Thiazolidinediones; Troglitazone | 2004 |
Enhanced activity of angiotensin II-sensitive neurons in the anterior hypothalamic area of spontaneously hypertensive rats.
Topics: Action Potentials; Analysis of Variance; Angiotensin II; Animals; Hypertension; Hypothalamus, Anterior; Male; Matched-Pair Analysis; Microinjections; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2004 |
Analysis of heart rate variability in hypertensive patients before and after treatment with angiotensin II-converting enzyme inhibitors.
Topics: Adolescent; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 2004 |
[Pregnanolone effects on the blood pressure of stress-induced hypertension in rats].
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Electric Stimulation; Hypertension; Male; Pregnanolone; Proto-Oncogene Proteins c-fos; Random Allocation; Rats; Rats, Wistar; Stress, Physiological | 2004 |
Vascular response to angiotensin II in upper body obesity.
Topics: Acetylcholine; Adult; Angiotensin II; Blood Glucose; Body Composition; Dose-Response Relationship, Drug; Forearm; Humans; Hypertension; Insulin Resistance; Lipolysis; Male; Nitric Oxide Synthase; Nitroprusside; Obesity; omega-N-Methylarginine; Palmitic Acid; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2004 |
[Renal sequelae of sympathetic hyperactivity].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clonidine; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Hypothalamus; Imidazoline Receptors; Kidney; Norepinephrine; Receptors, Drug; Renal Insufficiency; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Treatment Outcome | 2004 |
In vivo administration of D-arginine: effects on blood pressure and vascular function in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Arginine; Disease Models, Animal; Hypertension; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vascular Resistance | 2004 |
Angiotensin II type 2 receptor gene transfer elicits cardioprotective effects in an angiotensin II infusion rat model of hypertension.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiomyopathies; Cardiotonic Agents; Disease Models, Animal; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Hypertension; Hypertrophy, Left Ventricular; Infusion Pumps, Implantable; Lentivirus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2 | 2004 |
Relationship between plasma angiotensinII, leptin and arterial blood pressure.
Topics: Adult; Angiotensin II; Biomarkers; Body Mass Index; Case-Control Studies; Female; Humans; Hypertension; Leptin; Obesity; Probability; Prognosis; Reference Values; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index | 2004 |
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension.
Topics: Amidohydrolases; Angiotensin II; Animals; Arachidonic Acids; Benzamides; Benzyl Compounds; Blood Pressure; Camphanes; Carbamates; Dronabinol; Endocannabinoids; Endothelium, Vascular; Hypertension; Male; Models, Cardiovascular; Myocardial Contraction; Myocardium; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Up-Regulation; Vascular Resistance; Vasodilation; Ventricular Function, Left | 2004 |
Contribution of the subfornical organ to angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drinking; Heart Rate; Hexamethonium; Hypertension; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium; Subfornical Organ; Sympathetic Nervous System; Telemetry; Vasoconstrictor Agents; Water | 2005 |
Tissue distribution of antihypertensive dipeptide, Val-Tyr, after its single oral administration to spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dipeptides; Hypertension; Rats; Rats, Inbred SHR; Tissue Distribution | 2004 |
Time-dependent transition of tempol-sensitive reduction of blood pressure in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Antioxidants; Aorta; Blood Pressure; Cyclic N-Oxides; Heart; Hypertension; Male; Mitogen-Activated Protein Kinases; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spin Labels; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Salt-induced ANG II suppression impairs the response of cerebral artery smooth muscle cells to prostacyclin.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Cerebral Arteries; Epoprostenol; Hypertension; Iloprost; Losartan; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Serotonin; Sodium Chloride; Vasodilation; Vasodilator Agents | 2005 |
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclic N-Oxides; Disease Models, Animal; Glucose; Hypertension; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan | 2005 |
[Changes of angiotensin II and its receptor during the development of chronic intermittent hypoxia-induced hypertension in rats].
Topics: Angiotensin II; Animals; Hypertension; Hypoxia; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger | 2004 |
Genetic AT1A receptor deficiency attenuates cold-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cold Temperature; Drinking; Heart; Hypertension; Kidney; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Receptor, Angiotensin, Type 1 | 2005 |
Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Amino Acid Sequence; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Cerebrovascular Circulation; Cytochromes b; Endothelium, Vascular; Free Radical Scavengers; Free Radicals; Glycoproteins; Hypercapnia; Hyperemia; Hypertension; Laser-Doppler Flowmetry; Losartan; Male; Membrane Glycoproteins; Metalloporphyrins; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide Donors; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; S-Nitroso-N-Acetylpenicillamine; Somatosensory Cortex; Superoxide Dismutase; Vibrissae | 2004 |
AT1 receptor in rostral ventrolateral medulla mediating blunted baroreceptor reflex in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Heart Rate; Hypertension; Losartan; Male; Medulla Oblongata; Oligodeoxyribonucleotides, Antisense; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1 | 2004 |
Contractile responses of aortae from WKY and SHR to vasoconstrictors.
Topics: Age Factors; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Endothelin-1; Heart Rate; Hypertension; In Vitro Techniques; Male; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Urotensins; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Sex-specific effects of dual ET-1/ANG II receptor (Dear) variants in Dahl salt-sensitive/resistant hypertension rat model.
Topics: Angiotensin II; Animals; Animals, Congenic; Base Sequence; Blood Pressure; Blotting, Western; Cell Membrane; Cohort Studies; Crosses, Genetic; DNA, Complementary; Endothelin-1; Female; Genetic Linkage; Genetic Predisposition to Disease; Genetic Variation; Hypertension; Kinetics; Ligands; Male; Molecular Sequence Data; Phenotype; Polymorphism, Single-Stranded Conformational; Protein Binding; Rats; Rats, Inbred Dahl; Salts; Sex Factors; Sodium Chloride; Sodium Chloride Symporters; Sodium Chloride, Dietary; Species Specificity | 2005 |
[Study on the polymorphism of angiotensin converting enzyme genes and serum angiotensin II level in patients with obstructive sleep apnea hypopnea syndrome accompanied hypertension].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Sleep Apnea, Obstructive | 2004 |
The vascular relaxing effects of sevoflurane and isoflurane are more important in hypertensive than in normotensive rats.
Topics: Anesthetics, Inhalation; Angiotensin II; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoflurane; Male; Methyl Ethers; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sevoflurane; Vasoconstriction | 2004 |
Sex differences in the development of angiotensin II-induced hypertension in conscious mice.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Consciousness; Female; Ganglionic Blockers; Heart Rate; Hexamethonium; Hypertension; Male; Mice; Mice, Inbred C57BL; Orchiectomy; Ovariectomy; Sex Characteristics; Sympathetic Nervous System; Vasoconstrictor Agents | 2005 |
Dual angiotensin II and endothelin A receptor antagonists: synthesis of 2'-substituted N-3-isoxazolyl biphenylsulfonamides with improved potency and pharmacokinetics.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Dogs; Endothelin A Receptor Antagonists; Humans; Hypertension; Irbesartan; Isoxazoles; Macaca fascicularis; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Structure-Activity Relationship; Sulfonamides; Tetrazoles | 2005 |
Development of angiotensin II-induced hypertension: role of CGRP and its receptor.
Topics: Angiotensin II; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Receptor-Like Protein; Ganglia, Spinal; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mesenteric Arteries; Miotics; Peptide Fragments; Rats; Rats, Wistar; Receptor Activity-Modifying Proteins; Receptors, Calcitonin; Vasoconstrictor Agents | 2005 |
F2-Isoprostane level is associated with the angiotensin II type 1 receptor -153A/G gene polymorphism.
Topics: Adult; Angiotensin II; F2-Isoprostanes; Female; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2005 |
Endothelin mediates superoxide production in angiotensin II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Peptides, Cyclic; Propionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Superoxides | 2005 |
Double trouble for type 1 angiotensin receptors in atherosclerosis.
Topics: Angiotensin II; Animals; Arteriosclerosis; Dimerization; Factor XIIIa; Humans; Hyperlipidemias; Hypertension; Mice; Monocytes; Receptor, Angiotensin, Type 1; Transglutaminases | 2005 |
Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of insulinlike growth factor-1 receptor transactivation.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Cell Culture Techniques; Disease Models, Animal; Hypertension; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NADPH Oxidases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptor, IGF Type 1; Transcriptional Activation; Vasoconstrictor Agents | 2005 |
Protein kinase C activation-induced increases of neural activity are enhanced in the hypothalamus of spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Action Potentials; Angiotensin II; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Hypertension; Hypothalamus; Male; Neurons; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2005 |
Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Blood Vessels; Calcium; Cells, Cultured; Cyclic N-Oxides; Decanoic Acids; Diazoxide; Enzyme Activation; Hydroxy Acids; Hypertension; Intracellular Membranes; Male; Membrane Potentials; Mitochondria; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Superoxides; Vasoconstrictor Agents | 2005 |
Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension.
Topics: Adamantane; Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Epoxide Hydrolases; Hydroxyeicosatetraenoic Acids; Hypertension; In Vitro Techniques; Lauric Acids; Male; Mice; Mice, Inbred Strains; Natriuresis; Renal Circulation; Solubility; Sulfones; Vasoconstrictor Agents; Vasodilation | 2005 |
Fenofibrate prevents the development of angiotensin II-dependent hypertension in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Fenofibrate; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Vasoconstrictor Agents | 2005 |
Antifibrotic effect of adrenomedullin on coronary adventitia in angiotensin II-induced hypertensive rats.
Topics: Actins; Adrenomedullin; Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiotonic Agents; Cell Differentiation; Cell Division; Cell Size; Collagen Type I; Connective Tissue; Fibroblasts; Heart Ventricles; Humans; Hypertension; Male; Myocytes, Cardiac; Peptides; Rats; Rats, Wistar; Recombinant Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Remodeling | 2005 |
Genistein inhibits expressions of NADPH oxidase p22phox and angiotensin II type 1 receptor in aortic endothelial cells from stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Anilides; Animals; Aorta, Thoracic; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; Genistein; Hypertension; Male; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; PPAR gamma; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Signal Transduction; Stroke; Superoxides; Tyrosine; Vasoconstrictor Agents | 2004 |
Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Chronic Disease; Collagen; Humans; Hypertension; Kidney; Membrane Glycoproteins; Mice; Mice, Transgenic; Myocardium; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; Renin; Tyrosine | 2005 |
Effects of lipopolysaccharide on the blood-brain barrier permeability in prolonged nitric oxide blockade-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Astrocytes; Blood-Brain Barrier; Capillary Permeability; Cerebellum; Coloring Agents; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Hypertension; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphoproteins; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Zonula Occludens-1 Protein | 2005 |
Decreased plasma levels of nitric oxide metabolites, angiotensin II, and aldosterone in spontaneously hypertensive rats exposed to 5 mT static magnetic field.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Radiation; Electromagnetic Fields; Heart Rate; Hypertension; Male; Nitric Oxide; Rats; Skin; Whole-Body Irradiation | 2005 |
Enhanced activation of RhoA by angiotensin II in SHR preglomerular microvascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Hypertension; Kidney Glomerulus; Male; Microcirculation; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rhoA GTP-Binding Protein | 2005 |
Angiotensin II-induced over-activation of p47phox in fibroblasts from hypertensives: which role in the enhanced ERK1/2 responsiveness to angiotensin II?
Topics: Acetophenones; Adult; Angiotensin II; Antioxidants; Cell Membrane; Cells, Cultured; Cytosol; Fibroblasts; Free Radicals; Humans; Hypertension; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Phosphoproteins; Phosphorylation; Reactive Oxygen Species; Vasoconstrictor Agents | 2005 |
Increased expression of IL-6 and LIF in the hypertrophied left ventricle of TGR(mRen2)27 and SHR rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Blood Pressure; Ciliary Neurotrophic Factor; Cytokines; Female; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Interleukin-6; Leukemia Inhibitory Factor; Male; Organ Size; Proteins; Rats; Rats, Inbred SHR; Renin; RNA, Messenger; Up-Regulation | 2005 |
Angiotensin II-induced hypertension in mice caused an increase in insulin secretion.
Topics: Angiotensin II; Animals; Cell Line; Hypertension; Insulin; Insulin Secretion; Male; Mice; Mice, Inbred C57BL | 2005 |
Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance.
Topics: Adipocytes; Angiotensin II; Animals; Cell Size; Dietary Fats; Energy Metabolism; Hypertension; Imidazoles; Insulin Resistance; Mice; Mice, Knockout; Muscle, Skeletal; Obesity; Pyridines; Receptor, Angiotensin, Type 2 | 2005 |
Effects of angiotensin II and leptin on blood pressure.
Topics: Angiotensin II; Biomarkers; Humans; Hypertension; Leptin | 2005 |
Is there an answer?
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Leukocytes, Mononuclear; NADPH Oxidases; Oxidative Stress; Oxygen; Peroxidase | 2004 |
Angiotensin II increases human monocyte matrix metalloproteinase-1 through the AT2 receptor and prostaglandin E2: implications for atherosclerotic plaque rupture.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Cells, Cultured; Coronary Artery Disease; Dinoprostone; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypertension; Imidazoles; Matrix Metalloproteinase 1; Monocytes; Myocardial Infarction; Oligopeptides; Phosphoprotein Phosphatases; Pyridines; Receptor, Angiotensin, Type 2; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Protection from angiotensin II-mediated vasculotoxic and hypertensive response in mice lacking PI3Kgamma.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Hypertension; Isoenzymes; Male; Mesenteric Arteries; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Reactive Oxygen Species; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Angiotensin II type 2 receptors contribute to vascular responses in spontaneously hypertensive rats treated with angiotensin II type 1 receptor antagonists.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Heart Rate; Hypertension; Losartan; Male; Nitric Oxide; Nitroprusside; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Vasoconstriction; Vasodilation | 2005 |
Possible involvement of aminopeptidase A in hypertension and renal damage in Dahl salt-sensitive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Progression; Dose-Response Relationship, Drug; Glomerulosclerosis, Focal Segmental; Glutamyl Aminopeptidase; Hyalin; Hypertension; Immunohistochemistry; Kidney; Kidney Diseases; Kidney Glomerulus; Male; Rats; Rats, Inbred Dahl; Severity of Illness Index; Sodium Chloride, Dietary; Staining and Labeling | 2005 |
Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Atenolol; Carboxypeptidases; Carotid Arteries; Gene Expression Regulation, Enzymologic; Hydralazine; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Vasodilator Agents | 2005 |
Determinants of hypertension-related cardiac organ damage: beyond the haemodynamic overload.
Topics: Angiotensin II; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular; Sympathetic Nervous System | 2005 |
Negative regulation of RhoA/Rho kinase by angiotensin II type 2 receptor in vascular smooth muscle cells: role in angiotensin II-induced vasodilation in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; rhoA GTP-Binding Protein; Stroke; Vasodilation | 2005 |
Angiotensin II and norepinephrine release: interaction and effects on the heart.
Topics: Adult; Aged; Angiotensin II; Female; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Norepinephrine; Sympathetic Nervous System | 2005 |
EGF receptor transactivation in angiotensin II and endothelin control of vascular protein synthesis in vivo.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelins; ErbB Receptors; Heart Rate; Hypertension; Infusion Pumps, Implantable; Mesenteric Arteries; Protein Biosynthesis; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrphostins | 2004 |
Effects of endothelin receptor antagonist on expression of AT1 and AT2 receptors in the heart of SHR-SP.
Topics: Angiotensin II; Animals; Coronary Vessels; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Hypertension; Indans; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Stroke | 2004 |
Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats.
Topics: Angiotensin II; Animals; Cells, Cultured; Common Bile Duct; Hepatitis; Hepatocytes; Hypertension; Ligation; Liver Cirrhosis; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thrombosis; Vasoconstrictor Agents | 2005 |
Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiomegaly; Cells, Cultured; Cyclooxygenase Inhibitors; Hypertension; Lactones; Male; Myocardium; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones | 2005 |
Effects of atorvastatin on blood-brain barrier permeability during L-NAME hypertension followed by angiotensin-II in rats.
Topics: Angiotensin II; Animals; Atorvastatin; Blood-Brain Barrier; Heptanoic Acids; Hypertension; Male; NG-Nitroarginine Methyl Ester; Permeability; Pyrroles; Rats; Rats, Wistar | 2005 |
Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Hypertension; Kidney Diseases; Male; Rats; Rats, Inbred SHR | 2005 |
GLUT4 facilitative glucose transporter specifically and differentially contributes to agonist-induced vascular reactivity in mouse aorta.
Topics: Angiotensin II; Animals; Aorta; Cattle; Cells, Cultured; Dinoprost; Endothelial Cells; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; HIV Protease Inhibitors; Hypertension; Indinavir; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Norepinephrine; Serotonin; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Sexual dimorphism in angiotensin II-induced hypertension and vascular alterations.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Drinking; Eating; Female; Hypertension; Male; Norepinephrine; Perfusion; Potassium Chloride; Rats; Rats, Sprague-Dawley; Serotonin; Sex Characteristics; Splanchnic Circulation; Vasoconstriction | 2005 |
Failure of angiotensin II to suppress plasma renin activity in normotensive subjects with a positive family history of hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Humans; Hypertension; Irbesartan; Male; Renal Circulation; Renin; Renin-Angiotensin System; Sodium; Tetrazoles | 2005 |
Baroreceptor denervation prevents sympathoinhibition during angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Denervation; Hypertension; Kidney; Neural Inhibition; Pressoreceptors; Rabbits; Sinoatrial Node; Sinus of Valsalva; Sympathetic Nervous System; Vasoconstrictor Agents | 2005 |
Increased expression of endothelial lipase in rat models of hypertension.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Aorta; Base Sequence; Blotting, Northern; Cells, Cultured; Humans; Hypertension; Kidney; Lipase; Lung; Male; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; RNA, Messenger; Sequence Alignment; Stroke; Tetradecanoylphorbol Acetate | 2005 |
Alterations in aldosterone and angiotensin II levels in salt-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Glutathione; Glutathione Disulfide; Heart; Heart Rate; Hypertension; Kidney; Male; Mesenteric Arteries; Microcirculation; Myocardium; Organ Size; Rats; Rats, Inbred Dahl; Renin-Angiotensin System; Sodium Chloride, Dietary | 2005 |
ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Blood Vessels; Cell Membrane; Cytoplasm; Enzyme Activation; Enzyme Inhibitors; Glucose; Glucose Transporter Type 4; Hypertension; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monosaccharide Transport Proteins; Muscle Proteins; Myocytes, Smooth Muscle; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Tyrosine | 2005 |
NAD(P)H-dependent superoxide production in platelets: the role of angiotensin II and protein kinase C.
Topics: Aged; Alkaloids; Angiotensin II; Angiotensin Receptor Antagonists; Benzophenanthridines; Blood Platelets; Female; Humans; Hypertension; Male; Membrane Glycoproteins; Middle Aged; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Phenanthridines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Valine; Valsartan | 2005 |
Glomerular permeability defect in hypertension is dependent on renin angiotensin system activation.
Topics: Albumins; Angiotensin II; Animals; Blood Pressure; Cell Membrane Permeability; Desoxycorticosterone; Disease Models, Animal; Follow-Up Studies; Glomerular Filtration Rate; Hypertension; Kidney Glomerulus; Male; Radioimmunoassay; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Wistar; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 2005 |
Correction of endothelial dysfunction by tetrahydrobiopterin: new hope for the treatment of arterial hypertension?
Topics: Angiotensin II; Animals; Antioxidants; Biopterins; Cardiomegaly; Endothelium, Vascular; Hypertension; Immunohistochemistry; Male; Myocardium; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Tyrosine; Up-Regulation | 2005 |
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Cardiomegaly; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Male; NADPH Oxidases; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Time Factors; Tyrosine; Up-Regulation | 2005 |
Early and sustained inhibition of nuclear factor-kappaB prevents hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Chemokine CCL2; Hypertension; Intercellular Adhesion Molecule-1; Male; NF-kappa B; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thiocarbamates | 2005 |
Differential effects of angiotensin II type-1 receptor antisense oligonucleotides on renal function in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diuresis; Histocytochemistry; Hypertension; Kidney; Male; Natriuresis; Oligonucleotides, Antisense; Potassium; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renin | 2005 |
Continuous inhibition of the renin-angiotensin system and protection from hypertensive end-organ damage by brief treatment with angiotensin II type 1 receptor blocker in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomegaly; Cerebral Cortex; Histocytochemistry; Hypertension; Intercellular Adhesion Molecule-1; Kidney; Male; Myocardium; Nephrosclerosis; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Stroke | 2005 |
Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atenolol; Blood Pressure; Cardiomegaly; Doxazosin; Drug Therapy, Combination; Echocardiography; Heart Rate; Hypertension; Losartan; Male; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; RNA, Messenger | 2005 |
Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Blood Vessels; Glucosephosphate Dehydrogenase Deficiency; Hypertension; Hypertrophy; Male; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Phosphorylation; Proto-Oncogene Proteins c-akt; Superoxides | 2005 |
Growing old, angiotensin II, cardiac hypertrophy, and death: making the connection with p66Shc.
Topics: Adaptor Proteins, Signal Transducing; Aging; Angiotensin II; Animals; Cardiomegaly; Humans; Hypertension; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1 | 2005 |
The role of intrarenal angiotensin II in the development of hypertension in Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Western; Hypertension; Kidney; Proteins; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Tetrazoles | 2005 |
Prolonged attenuation of cold-induced hypertension by adenoviral delivery of renin antisense.
Topics: Adenoviridae; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cold Temperature; DNA, Antisense; Galactosides; Genetic Therapy; Hypertension; Indoles; Lac Operon; Rats; Rats, Sprague-Dawley; Renin | 2005 |
Effects of angiotensin II on the action potential durations of atrial myocytes in hypertensive rats.
Topics: Action Potentials; Angiotensin II; Animals; Enzyme Inhibitors; Hypertension; Myocytes, Cardiac; Patch-Clamp Techniques; Radioimmunoassay; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2005 |
Blood pressure variability, cardiac baroreflex sensitivity and organ damage in experimentally hypertensive rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Blood Pressure Determination; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Hypertension; Hypertension, Renovascular; Interleukin-1; Kidney Glomerulus; Male; Myocardium; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
A new ATP-sensitive potassium channel opener protects the kidney from hypertensive damage in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; ATP-Binding Cassette Transporters; Benzazepines; Endothelin-1; Extracellular Matrix; Hemodynamics; Hypertension; Immunohistochemistry; KATP Channels; Kidney; Kidney Diseases; Kidney Function Tests; Potassium Channels, Inwardly Rectifying; Propylamines; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiomegaly; Collagen; Disease Progression; Endothelium, Vascular; Heart Rate; Hypertension; Imidazoles; Male; Mesenteric Arteries; Myocardium; Rats; Rats, Inbred SHR; Tetrazoles; Vascular Diseases; Vascular Resistance | 2005 |
Role of protein kinase C in Ca channel blocker-induced renal arteriolar dilation in spontaneously hypertensive rats--studies in the isolated perfused hydronephrotic kidney.
Topics: Angiotensin II; Animals; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydronephrosis; Hypertension; Kidney; Male; Mibefradil; Microcirculation; Nifedipine; Perfusion; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Staurosporine; Thapsigargin; Vasodilator Agents | 2005 |
Effects of captopril on the renin angiotensin system, oxidative stress, and endothelin in normal and hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Endothelins; Hypertension; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 2005 |
Vascular but not cardiac remodeling is associated with superoxide production in angiotensin II hypertension.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Hypertension; Luminescent Measurements; Male; Mesenteric Arteries; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxygen; Phosphoric Monoester Hydrolases; Rats; Rats, Sprague-Dawley; Superoxides; Vasoconstrictor Agents; Ventricular Remodeling | 2005 |
Cerebral vascular effects of angiotensin II: new insights from genetic models.
Topics: Angiotensin II; Angiotensinogen; Animals; Cerebral Arteries; Cerebrovascular Circulation; Endothelium, Vascular; Female; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1; Renin; rho-Associated Kinases; Sex Factors; Superoxides; Vasoconstriction | 2006 |
Iron chelation suppresses ferritin upregulation and attenuates vascular dysfunction in the aorta of angiotensin II-infused rats.
Topics: Aldehydes; Angiotensin II; Animals; Aorta; Aortic Diseases; Apoferritins; Chemokine CCL2; Deferoxamine; Ferritins; Heme Oxygenase-1; Hypertension; Iron; Iron Chelating Agents; Iron Overload; Iron-Dextran Complex; Male; Norepinephrine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Transferrin; RNA, Messenger; Up-Regulation; Vasoconstrictor Agents; Vasodilation | 2005 |
Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cyclic AMP; Female; G-Protein-Coupled Receptor Kinase 5; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Ovariectomy; Potassium Channels; Potassium Chloride; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sex Characteristics; Signal Transduction; Transgenes; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2005 |
Expression and localization of N-domain ANG I-converting enzymes in mesangial cells in culture from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Cells, Cultured; Hypertension; Immunochemistry; Mesangial Cells; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Wistar; RNA, Messenger; Sequence Homology; Subcellular Fractions | 2006 |
Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Annexin A1; Annexins; Cells, Cultured; Down-Regulation; Gene Expression Regulation; Hypertension; Magnesium; Muscle, Smooth, Vascular; Protein Transport; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; TRPM Cation Channels | 2006 |
Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension.
Topics: Adenosine; Adenosine Triphosphate; Angiotensin II; Animals; Arterioles; Blood Pressure; Calcium; Calcium Signaling; Homeostasis; Hypertension; Intracellular Membranes; Kidney; Male; Microcirculation; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Uridine Triphosphate; Vasoconstriction | 2005 |
Caffeic acid inhibits vascular smooth muscle cell proliferation induced by angiotensin II in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antioxidants; Caffeic Acids; Cell Division; DNA-Binding Proteins; Drug Interactions; Enzyme Inhibitors; HSP90 Heat-Shock Proteins; Hypertension; Janus Kinase 2; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; STAT1 Transcription Factor; Stroke; Superoxides; Trans-Activators; Tyrosine; Tyrphostins; Vasoconstrictor Agents | 2005 |
Role of chymase-dependent angiotensin II formation in regulating blood pressure in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Body Weight; Chymases; Gene Expression Regulation, Enzymologic; Hypertension; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Serine Endopeptidases; Vasoconstriction | 2005 |
Heat shock treatment suppresses angiotensin II-induced SP-1 and AP-1 and stimulates Oct-1 DNA-binding activity in heart.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Blood Pressure; Blotting, Western; Cell Nucleus; DNA; DNA-Binding Proteins; Heat-Shock Proteins; Hot Temperature; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hypertension; Inflammation; Male; Myocardium; Neoplasm Proteins; Octamer Transcription Factor-1; Oligonucleotides; Protein Binding; Rats; Rats, Sprague-Dawley; Signal Transduction; Sp1 Transcription Factor; Time Factors; Transcription Factor AP-1; Transcription Factors | 2005 |
Relaxin increases cardiac output and reduces systemic arterial load in hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Cardiac Output; Compliance; Drug Administration Schedule; Female; Humans; Hypertension; Infusion Pumps; Injections, Intravenous; Male; Rats; Rats, Inbred SHR; Rats, Long-Evans; Recombinant Proteins; Relaxin; Vascular Resistance; Vasoconstrictor Agents | 2005 |
Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2.
Topics: Angiotensin II; Animals; Aorta; Catalase; Humans; Hydrogen Peroxide; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Messenger; Vasoconstrictor Agents | 2005 |
Antihypertensive effect of total flavonoid fraction of Astragalus complanatus in hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Astragalus Plant; Flavonoids; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Renin; Systole | 2005 |
Fetal and neonatal consequences of antenatal exposure to type 1 angiotensin II receptor-antagonists.
Topics: Abnormalities, Multiple; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diagnosis, Differential; Female; Humans; Hypertension; Infant, Newborn; Male; Pregnancy; Pregnancy Complications, Cardiovascular; Radiography | 2005 |
Angiotensin-converting enzyme 2 (ACE2) and ACE activities display tissue-specific sensitivity to undernutrition-programmed hypertension in the adult rat.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Blood Pressure; Carboxypeptidases; Corticosterone; Disease Susceptibility; Electrolytes; Female; Hypertension; Kidney; Lung; Male; Malnutrition; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred WKY; Renin; Tissue Distribution | 2005 |
Influence of prolonged baroreflex activation on arterial pressure in angiotensin hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Blood Proteins; Dogs; Drug Administration Schedule; Electrolytes; Heart Rate; Hematocrit; Hypertension; Male; Neurotransmitter Agents; Norepinephrine; Time Factors; Vasoconstrictor Agents | 2005 |
[Effects of angiotensin II on extracellular signal-regulated protein kinases signaling pathway in cultured vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Cells, Cultured; Dual Specificity Phosphatase 1; Extracellular Signal-Regulated MAP Kinases; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Tetrazoles; Valine; Valsartan | 2005 |
Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Genotype; Hypertension; Hypertrophy, Left Ventricular; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Rats; Rats, Inbred Lew; Rats, Mutant Strains | 2006 |
Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice.
Topics: Angiotensin II; Animals; Genes, Reporter; Green Fluorescent Proteins; Humans; Hypertension; Hypertrophy; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; NADPH Oxidase 1; NADPH Oxidases | 2005 |
Oxidative stress and the vascular wall: NADPH oxidases take center stage.
Topics: Angiotensin II; Animals; Blood Vessels; Endothelium, Vascular; Humans; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; NADPH Oxidase 1; NADPH Oxidases; Oxidative Stress | 2005 |
Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice.
Topics: Angiotensin II; Animals; Biological Availability; Blood Pressure; Disease Models, Animal; Heart Rate; Hypertension; Mice; Mice, Inbred Strains; Mice, Knockout; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide; Reactive Oxygen Species | 2005 |
Dominant-negative c-Jun inhibits rat cardiac hypertrophy induced by angiotensin II and hypertension.
Topics: Adenoviridae; Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Chemokine CCL2; Collagen Type I; Collagen Type III; Collagen Type IV; Gene Deletion; Genes, Dominant; Genetic Therapy; Genetic Vectors; Hypertension; Injections; Male; Models, Animal; Natriuretic Peptide, Brain; Phosphorylation; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Transcription Factor AP-1 | 2006 |
Telmisartan inhibits expression of a receptor for advanced glycation end products (RAGE) in angiotensin-II-exposed endothelial cells and decreases serum levels of soluble RAGE in patients with essential hypertension.
Topics: Administration, Oral; Age Factors; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Benzimidazoles; Benzoates; Blotting, Western; Coronary Artery Disease; Disease Progression; DNA Primers; Endothelial Cells; Endothelium, Vascular; Female; Humans; Hypertension; Male; Microcirculation; Middle Aged; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Telmisartan; Time Factors; Up-Regulation | 2005 |
Simvastatin and losartan enhance nitric oxide and reduce oxidative stress in salt-induced hypertension.
Topics: Acetylcholine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Body Weight; Drug Therapy, Combination; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; In Vitro Techniques; Kidney; Losartan; Male; Mesenteric Arteries; Myocardium; Nitric Oxide; Organ Size; Oxidative Stress; Prostaglandins; Rats; Rats, Inbred Dahl; Simvastatin; Sodium Chloride, Dietary; Superoxides; Thromboxane A2; Treatment Outcome; Vasoconstriction; Vasodilator Agents | 2005 |
Angiotensin II hypertension is attenuated in interleukin-6 knockout mice.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; Severity of Illness Index; Sodium Chloride, Dietary | 2006 |
Angiotensin II blockade improves mitochondrial function in spontaneously hypertensive rats.
Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Creatinine; Electron Transport Complex IV; Hydrogen Peroxide; Hypertension; Immunohistochemistry; Kidney Cortex; Male; Membrane Potentials; Mitochondria; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 2005 |
Selective angiotensin II receptor antagonism enhances whole-body insulin sensitivity and muscle glucose transport in hypertensive TG(mREN2)27 rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biological Transport; Biphenyl Compounds; Glucose; Glucose Transporter Type 4; Glycogen Synthase; Hypertension; Insulin Receptor Substrate Proteins; Insulin Resistance; Irbesartan; Male; Mice; Muscle, Skeletal; Phosphoproteins; Rats; Renin; Tetrazoles | 2005 |
Role of angiotensin type-1 and angiotensin type-2 receptors in the expression of vascular integrins in angiotensin II-infused rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Vessels; Hydralazine; Hypertension; Infusion Pumps; Integrins; Losartan; Male; Osteopontin; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sialoglycoproteins; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
L-NAME hypertension: trying to fit the pieces together.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cardiovascular System; Enzyme Inhibitors; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandins; Rats; Renin-Angiotensin System; Superoxides; Sympathetic Nervous System | 2006 |
Angiotensin II as a multifunctional hormone: a regulator of haemodynamics and metabolism with potential roles in the etiologies of hypertension and the metabolic syndrome.
Topics: Angiotensin II; Animals; Atherosclerosis; Blood Glucose; Cholesterol; Hemodynamics; Hypertension; Metabolic Syndrome; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2006 |
Blood pressure vaccine shot down by safety concerns.
Topics: Angiotensin II; Antibodies; Drug-Related Side Effects and Adverse Reactions; Humans; Hypertension; Vaccines | 2005 |
Significance of angiotensin II receptor blocker lipophilicities and their protective effect against vascular remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Body Weight; Carotid Artery Diseases; Gene Expression; Hypertension; Immunohistochemistry; Lipids; Losartan; Male; Membrane Transport Proteins; Myocardium; NADPH Oxidases; Nitric Oxide Synthase Type III; Organ Size; Phosphoproteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Telmisartan; Vasodilation | 2005 |
Altered expression of renal bumetanide-sensitive sodium-potassium-2 chloride cotransporter and Cl- channel -K2 gene in angiotensin II-infused hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Gene Expression Regulation; Hypertension; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1 | 2005 |
Angiotensin II infusion alters vascular function in mouse resistance vessels: roles of O and endothelium.
Topics: Angiotensin II; Animals; Arterioles; Biological Factors; Blood Pressure; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Hypertension; Male; Membrane Transport Proteins; Mesenteric Arteries; Mice; Mice, Inbred C57BL; NADP; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Phosphoproteins; RNA, Messenger; Superoxides; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Reduced NAD(P)H oxidase in low renin hypertension: link among angiotensin II, atherogenesis, and blood pressure.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Atherosclerosis; Blood Pressure; Chemokine CCL2; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Hypertrophy, Left Ventricular; In Vitro Techniques; Membrane Glycoproteins; Mice; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Osmolar Concentration; Rats; Rats, Inbred Dahl; Renin; RNA, Messenger; Scavenger Receptors, Class E; Sodium Chloride, Dietary; Systole; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Triple vasopeptidase inhibition normalizes blood pressure in conscious, unrestrained, and spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Benzazepines; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Hypertension; Indoles; Male; Metalloendopeptidases; Neprilysin; Nitric Oxide; Organophosphonates; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species | 2005 |
Pancreatic polypeptide-fold peptide receptors and angiotensin II-induced renal vasoconstriction.
Topics: Angiotensin II; Animals; Blood Vessels; Blotting, Western; Hypertension; In Vitro Techniques; Kidney; Male; Neuropeptide Y; Peptide Fragments; Peptide YY; Perfusion; Pressure; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Receptors, Neuropeptide Y; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstriction | 2006 |
Enhanced central hypertonic saline-induced activation of angiotensin II-sensitive neurons in the anterior hypothalamic area of spontaneously hypertensive and Dahl S rats.
Topics: Action Potentials; Amiloride; Angiotensin II; Animals; Anterior Hypothalamic Nucleus; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Synergism; Hypertension; Male; Neurons; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY; Saline Solution, Hypertonic; Sodium; Vasoconstrictor Agents | 2006 |
RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Hypertension; Kidney; Male; Membrane Transport Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; Time Factors | 2006 |
Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Collagen; Ectodysplasins; Fibrosis; Heart; Hypertension; Hypertrophy; Macrophages; Male; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Myocarditis; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Spironolactone; Transcription Factor AP-1; Tumor Necrosis Factors; Vascular Cell Adhesion Molecule-1 | 2005 |
Genetic AVP deficiency abolishes cold-induced diuresis but does not attenuate cold-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Aquaporin 2; Arginine Vasopressin; Body Water; Body Weight; Cold Temperature; Diuresis; Drinking; Eating; Heart; Hypertension; Kidney; Organ Size; Osmolar Concentration; Rats; Rats, Brattleboro; Rats, Long-Evans; Receptors, Vasopressin; RNA, Messenger; Urine | 2006 |
Differential expression of nuclear AT1 receptors and angiotensin II within the kidney of the male congenic mRen2. Lewis rat.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Congenic; Animals, Genetically Modified; Cell Membrane; Cell Nucleus; Crosses, Genetic; Heterozygote; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Mice; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin | 2006 |
Effects of total flavonoids of Hippophae rhamnoides L. on intracellular free calcium in cultured vascular smooth muscle cells of spontaneously hypertensive rats and Wistar-Kyoto rats.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Flavonoids; Flavonols; Hippophae; Hypertension; Muscle, Smooth, Vascular; Norepinephrine; Quercetin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Verapamil | 2005 |
Growth factor receptor transactivation in mediating end organ damage by angiotensin II.
Topics: Angiotensin II; Animals; Humans; Hypertension; Receptors, Growth Factor; Transcriptional Activation | 2006 |
Pre- and postjunctional effects of angiotensin II in hypertension due to adenosine receptor blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Norepinephrine; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents; Xanthines | 2006 |
Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals.
Topics: Acetylcholine; Angiotensin II; Animals; Bradykinin; Calcimycin; Cerebrovascular Circulation; Endothelium, Vascular; Hypertension; Membrane Glycoproteins; Mice; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction | 2006 |
Enhanced angiotensin II-induced activation of Na+, K+-ATPase in the proximal tubules of obese Zucker rats.
Topics: Angiotensin II; Animals; Enzyme Activation; GTP-Binding Proteins; Hypertension; In Vitro Techniques; Kidney Tubules, Proximal; Male; Natriuresis; Obesity; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2006 |
Cardiac consequences of aldosterone excess in human hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cardiovascular System; Clinical Trials as Topic; Endomyocardial Fibrosis; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Longitudinal Studies; Renin-Angiotensin System; Retrospective Studies | 2006 |
Role of aldosterone in left ventricular hypertrophy in hypertension.
Topics: Adrenergic beta-Antagonists; Adrenocortical Adenoma; Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Echocardiography; Endomyocardial Fibrosis; Female; Heart Ventricles; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Male; Middle Aged; Proteinuria; Renin-Angiotensin System | 2006 |
Effects of changes in sodium balance on plasma and kidney angiotensin II levels in anesthetized and conscious Ren-2 transgenic rats.
Topics: Anesthesia, General; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium, Dietary | 2006 |
Androgens augment renal vascular responses to ANG II in New Zealand genetically hypertensive rats.
Topics: Age Factors; Androgens; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Enalapril; Gene Expression; Heart Rate; Hypertension; Kidney; Male; Orchiectomy; Organ Size; Rats; Rats, Inbred Strains; Receptor, Angiotensin, Type 1; Renal Artery; Renal Circulation; Testosterone | 2006 |
High- or low-salt diet from weaning to adulthood: effect on body weight, food intake and energy balance in rats.
Topics: Adipose Tissue, Brown; Angiotensin II; Animals; Body Weight; Carrier Proteins; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Eating; Energy Intake; Energy Metabolism; Hypertension; Ion Channels; Male; Membrane Proteins; Mitochondrial Proteins; Motor Activity; Rats; Rats, Wistar; Sodium Chloride, Dietary; Thyroid Hormones; Time Factors; Uncoupling Protein 1; Weaning | 2006 |
A novel gene (Cmya3) induced in the heart by angiotensin II-dependent but not salt-dependent hypertension in mice.
Topics: Angiotensin II; Animals; Aorta; Base Sequence; Blood Pressure; Brain; Gene Expression; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Myocardium; Polymerase Chain Reaction; Sequence Analysis, DNA; Sodium Chloride | 2006 |
Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta; Carboxypeptidases; Cardiac Output, Low; Cardiomegaly; Cells, Cultured; Constriction, Pathologic; Enzyme Activation; Gene Deletion; Gene Expression; Heart; Hypertension; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardium; Myocytes, Cardiac; Osmolar Concentration; Peptidyl-Dipeptidase A; RNA, Messenger | 2006 |
Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications.
Topics: Adult; Aged; Angiotensin II; Chymases; Diabetic Angiopathies; Female; Glycation End Products, Advanced; Humans; Hypertension; Male; Middle Aged; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serine Endopeptidases; Up-Regulation | 2006 |
Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cell Proliferation; Heterozygote; Hypertension; Immunohistochemistry; Kidney; Macrophages; Male; Mice; Nephrosclerosis; Rats; Rats, Sprague-Dawley; Renin | 2006 |
Altered vascular contractility in adult female rats with hypertension programmed by prenatal glucocorticoid exposure.
Topics: Acetylcholine; Aldosterone; Angiotensin II; Animals; Animals, Newborn; Aorta; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Female; Glucocorticoids; Hypertension; In Vitro Techniques; Infusion Pumps; Mesenteric Arteries; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Renin; Vasoconstriction | 2006 |
Prevention and reversal by enalapril of target organ damage in angiotensin II hypertension.
Topics: Acetophenones; Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Enalapril; Hypertension; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2005 |
Galphai2 expression, hypertension and insulin resistance.
Topics: Angiotensin II; Animals; Fibroblasts; GTP-Binding Protein alpha Subunit, Gi2; Humans; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation | 2006 |
[Preventive effect of trans-resveratrol on hypertension-induced cardiac hypertrophy in partially nephrectomized rats].
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Agents; Endothelin-1; Hypertension; Male; Myocardium; Nephrectomy; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
Role of renal sympathetic nerves in regulating renovascular responses to angiotensin II in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Electric Stimulation; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Renal Circulation; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance.
Topics: Adiponectin; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucose Tolerance Test; Hypertension; Imidazoles; Injections, Subcutaneous; Insulin; Insulin Resistance; Leptin; Male; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptors, Adiponectin; Receptors, Cell Surface; Tetrazoles; Tumor Necrosis Factor-alpha | 2006 |
Effects of enalapril, tempol, and eplerenone on salt-induced hypertension in dahl salt-sensitive rats.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enalapril; Eplerenone; Epoprostenol; Hypertension; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred Dahl; Sodium Chloride; Spin Labels; Spironolactone; Treatment Outcome | 2006 |
Essential role of Smad3 in angiotensin II-induced vascular fibrosis.
Topics: Adult; Aged; Angiotensin II; Aorta; Arteriosclerosis; Cells, Cultured; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hypertension; Male; MAP Kinase Signaling System; Middle Aged; Muscle, Smooth, Vascular; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad2 Protein; Smad3 Protein | 2006 |
Central and peripheral renin-angiotensin systems in ouabain-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cardiotonic Agents; Central Nervous System; Heart; Heart Rate; Hypertension; Kidney; Male; Ouabain; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Peripheral Nervous System; Preoptic Area; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subfornical Organ | 2006 |
Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Aorta; Dose-Response Relationship, Drug; Enzyme Activation; Hypertension; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; NADPH Oxidases; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2006 |
Cellular and molecular mechanisms of tissue protection by lipophilic calcium channel blockers.
Topics: Albumins; Amidohydrolases; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Arginine; Calcium Channel Blockers; Dihydropyridines; Gene Expression Regulation, Enzymologic; Hypertension; Kidney; Rats; Rats, Sprague-Dawley; Renin | 2006 |
AT1 receptor blockade regulates the local angiotensin II system in cerebral microvessels from spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Gene Expression Regulation; Hypertension; Male; Microcirculation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Tetrazoles | 2006 |
Oxidant stress and blood pressure responses to angiotensin II administration in rats fed varying salt diets.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Diet, Sodium-Restricted; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Infusions, Intravenous; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents | 2006 |
Angiotensin-converting enzyme and angiotensin II receptor subtype 1 inhibitors restitute hypertensive internal anal sphincter in the spontaneously hypertensive rats.
Topics: Anal Canal; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Blotting, Western; Captopril; Hypertension; Losartan; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rectum; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2006 |
Time course analysis of tyrosine hydroxylase and angiotensinogen mRNA expression in central nervous system of rats submitted to experimental hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Aortic Coarctation; Blood Pressure; Brain; Brain Stem; Catecholamines; Disease Models, Animal; Gene Expression; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred WKY; RNA, Messenger; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation | 2006 |
Effects of L/N-type calcium channel antagonist, cilnidipine on progressive renal injuries in Dahl salt-sensitive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Progression; Hemodynamics; Hypertension; Kidney; Kidney Cortex; Kidney Failure, Chronic; Kidney Function Tests; Male; Norepinephrine; Rats; Rats, Inbred Dahl; Renin; von Willebrand Factor | 2006 |
Effects of anesthesia on plasma and kidney ANG II levels in normotensive and ANG II-dependent hypertensive rats.
Topics: Anesthesia; Angiotensin II; Animals; Animals, Genetically Modified; Decapitation; Hypertension; Kidney; Male; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Renin; Stress, Physiological | 2006 |
The CARI guidelines. Prevention of progression of kidney disease.
Topics: Acidosis; Adult; Analgesics; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Child; Cyclosporine; Diabetic Nephropathies; Diet, Protein-Restricted; Exercise; Female; Fish Oils; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hyperuricemia; Kidney Diseases; Kidney Failure, Chronic; Phosphates; Pregnancy; Pregnancy Complications; Proteinuria; Renal Artery Obstruction; Smoking Cessation; Tonsillectomy | 2006 |
Contribution of reactive oxygen species to the pathogenesis of left ventricular failure in Dahl salt-sensitive hypertensive rats: effects of angiotensin II blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diastole; Gene Expression; Heart Failure; Heart Ventricles; Hypertension; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Ion Channels; Lung; Male; Membrane Transport Proteins; Mitochondrial Proteins; Myocardium; NADPH Oxidases; Natriuretic Peptide, Brain; Organ Size; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta; Uncoupling Protein 2; Ventricular Dysfunction, Left | 2006 |
Reduced expression of regulator of G-protein signaling 2 (RGS2) in hypertensive patients increases calcium mobilization and ERK1/2 phosphorylation induced by angiotensin II.
Topics: Adult; Angiotensin II; Calcium; Cells, Cultured; Cytosine; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Guanine; Humans; Hypertension; Intracellular Fluid; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Polymorphism, Single Nucleotide; RGS Proteins | 2006 |
The contribution of brain angiotensin II to the baroreflex regulation of renal sympathetic nerve activity in conscious normotensive and hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Brain Chemistry; Hypertension; Kidney; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Angiotensin; Sodium, Dietary; Sympathetic Nervous System | 2006 |
Construction of shRNA targeted to the rat angiotensin II type 1 receptors and its RNAi in cytoplasma.
Topics: Angiotensin II; Animals; Cytoplasm; Gene Silencing; Gene Targeting; Genetic Vectors; Hypertension; Rats; Rats, Inbred SHR; Receptors, Angiotensin; RNA, Small Interfering; Sequence Analysis, RNA | 2006 |
Abnormal renovascular parathyroid hormone-1 receptor in hypertension: Primary defect or secondary to angiotensin ii type 1 receptor activation?
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Cells, Cultured; Desoxycorticosterone; Down-Regulation; Hypertension; Kidney; Losartan; Male; Parathyroid Hormone-Related Protein; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Parathyroid Hormone, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasodilation | 2006 |
Exaggerated vasomotor response to ANG II in rats with fetal programming of hypertension associated with exposure to a low-protein diet during gestation.
Topics: Age Factors; Angiotensin II; Animal Feed; Animals; Antioxidants; Blotting, Western; Cyclic N-Oxides; Diet, Protein-Restricted; Dietary Proteins; Endothelium, Vascular; Female; Hypertension; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Spin Labels; Superoxide Dismutase; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Intravenous insulin-like growth factor-I receptor antisense treatment reduces angiotensin receptor expression and function in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antisense Elements (Genetics); Blood Pressure; Female; Hypertension; Injections, Intravenous; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, IGF Type 1; Vasoconstriction | 2006 |
Increased migration of vascular adventitial fibroblasts from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cell Movement; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Hypertension; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction | 2006 |
Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body Weight; Collagen; Connective Tissue Growth Factor; Creatine; Hypertension; Imidazoles; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Male; Nephrectomy; Organ Size; Peptidyl-Dipeptidase A; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium Chloride; Tetrazoles; Transforming Growth Factor beta | 2006 |
Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways.
Topics: Angiotensin II; Animals; Animals, Newborn; Antioxidants; Blotting, Northern; Blotting, Western; Cardiomegaly; Catechin; Electrophoretic Mobility Shift Assay; Enzyme Activation; ErbB Receptors; Hypertension; Male; MAP Kinase Kinase 4; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Transcription Factor AP-1 | 2006 |
Angiotensin II induces vascular dysfunction without exacerbating blood pressure elevation in a mouse model of menopause-associated hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Endothelium, Vascular; Female; Hypertension; Image Processing, Computer-Assisted; Mesenteric Arteries; Mice; Mice, Knockout; Models, Animal; Oxidative Stress; Postmenopause; Receptors, Angiotensin; Receptors, FSH; Renin-Angiotensin System; Telemetry | 2006 |
[Association of aldosterone synthase gene -344T/C polymorphism with plasma aldosterone and angiotensin II concentration in hypertensive patients].
Topics: Aged; Aldosterone; Angiotensin II; Cytochrome P-450 CYP11B2; Female; Gene Frequency; Genotype; Humans; Hypertension; Male; Middle Aged; Polymorphism, Single Nucleotide | 2006 |
ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 2006 |
Red wine polyphenols prevent angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase.
Topics: Acetylcholine; Angiotensin II; Animals; Endothelium, Vascular; Flavonoids; Hypertension; Immunohistochemistry; Male; NADPH Oxidases; Nitric Oxide; Nitroprusside; Phenols; Phenylephrine; Polyphenols; Rats; Rats, Wistar; Superoxides; Vasodilator Agents; Wine | 2006 |
Modulation of kinin B1 receptor expression by endogenous angiotensin II in hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Gene Expression Regulation; Hypertension; Kidney; Kinins; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2006 |
Estrogen and salt sensitivity in the female mRen(2). Lewis rat.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Estrogens; Female; Gene Expression Regulation; Heart Rate; Hypertension; Kidney Diseases; Ovariectomy; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2006 |
Chronic hyperinsulinemia enhances adrenergic vasoconstriction and decreases calcitonin gene-related peptide-containing nerve-mediated vasodilation in pithed rats.
Topics: Acetylcholine; Adrenergic Fibers; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Calcitonin Gene-Related Peptide; Cholesterol; Hyperinsulinism; Hypertension; Insulin; Insulin Resistance; Male; Nitroprusside; Norepinephrine; Rats; Rats, Wistar; Spinal Cord; Triglycerides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Nocturnal hypertension in mice consuming a high fructose diet.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Glucose; Body Weight; Brain Stem; Circadian Rhythm; Fructose; Glucose Intolerance; Glucose Tolerance Test; Heart Rate; Hypertension; Insulin; Insulin Resistance; Lipids; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Tissue Proteins; Prazosin; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Sympathetic Nervous System; Tyrosine 3-Monooxygenase | 2006 |
Role of extracellular superoxide dismutase in hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Hypertension; Isoenzymes; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Superoxide Dismutase; Superoxides; Vasoconstrictor Agents; Vasodilation; Vasomotor System | 2006 |
The inhibitory effect of leptin on angiotensin II-induced vasoconstriction is blunted in spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta; Biomarkers; Blotting, Western; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Leptin; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Isoforms; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Cell Surface; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstriction | 2006 |
Extracellular superoxide dismutase depletion in hypertension unmasks a new role for angiotensin II in regulating Cu,Zn-superoxide dismutase activity.
Topics: Angiotensin II; Animals; Extracellular Space; Hypertension; Superoxide Dismutase | 2006 |
Early gestation dexamethasone alters baroreflex and vascular responses in newborn lambs before hypertension.
Topics: Angiotensin II; Animals; Animals, Newborn; Baroreflex; Blood Pressure; Dexamethasone; Female; Gestational Age; Heart Rate; Hypertension; Injections, Intravenous; Male; Maternal Exposure; Models, Animal; Phenylephrine; Pregnancy; Sheep | 2006 |
Increased aldosterone/renin quotient in obese hypertensive women: a novel role for low-density lipoproteins?
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Glucose; Cells, Cultured; Female; Humans; Hypertension; Insulin; Lipoproteins, LDL; Middle Aged; Obesity; Renin | 2006 |
Reactive oxygen species impair sympathetic vasoregulation in skeletal muscle in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antioxidants; Cyclic N-Oxides; Hindlimb; Hypertension; Hypertension, Renovascular; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Sanguinarine downregulates AT1a gene expression in a hypertensive rat model.
Topics: Aldosterone; Alkaloids; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzophenanthridines; Blood Pressure; Body Weight; Down-Regulation; Gene Expression Regulation; Hypertension; Isoquinolines; Kidney; Male; Organ Size; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; RNA, Messenger; Sodium | 2006 |
Mechanics or mediators: arterial damage from high blood pressure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Humans; Hypertension; Mice | 2006 |
Angiotensin II, oxidative stress, and extracellular matrix degradation during transition to LV failure in rats with hypertension.
Topics: Angiotensin II; Animals; Base Sequence; Enzyme Activation; Extracellular Matrix; Heart Failure; Hypertension; Male; Matrix Metalloproteinases; Microscopy, Electron, Scanning; NADH, NADPH Oxidoreductases; NF-kappa B; Oxidative Stress; Rats; Rats, Inbred Dahl; RNA, Messenger; Ventricular Remodeling | 2006 |
ANG II-induced hypertension and the role of the area postrema during normal and increased dietary salt.
Topics: Angiotensin II; Animals; Area Postrema; Blood Pressure; Drug Synergism; Hypertension; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Water-Electrolyte Imbalance | 2007 |
Soluble guanylate cyclase stimulation on cardiovascular remodeling in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular System; Cells, Cultured; Guanylate Cyclase; Hypertension; Male; Pyrazoles; Pyridines; Rats; Rats, Wistar; Solubility | 2006 |
Reviewer critique of the sympathetic drive after acute myocardial infarction in hypertensive patients.
Topics: Acute Disease; Angiotensin II; Baroreflex; Blood Pressure; Female; Heart; Heart Rate; Humans; Hypertension; Insulin; Male; Middle Aged; Myocardial Infarction; Prognosis; Prospective Studies; Sympathetic Nervous System | 2006 |
High prevalence of ACE DD genotype among north Indian end stage renal disease patients.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Case-Control Studies; Creatinine; Disease Progression; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; India; Kidney; Kidney Failure, Chronic; Male; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Prevalence; Renin-Angiotensin System | 2006 |
[Protective and reverse effects of qindan capsule on aortic lesion in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Aorta; Capsules; Drugs, Chinese Herbal; Fibroblast Growth Factor 2; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger | 2006 |
Circulating renin Angiotensin system in childhood chronic renal failure: marked increase of Angiotensin-(1-7) in end-stage renal disease.
Topics: Adolescent; Angiotensin I; Angiotensin II; Angiotensins; Case-Control Studies; Child; Child, Preschool; Cross-Sectional Studies; Disease Progression; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 2006 |
Genetic clamping of renin gene expression induces hypertension and elevation of intrarenal Ang II levels of graded severity in Cyp1a1-Ren2 transgenic rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Gene Expression; Hypertension; Hypertension, Malignant; Indoles; Kidney; Male; Mice; Promoter Regions, Genetic; Rats; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2006 |
Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Genetic Vectors; Hypertension; Imidazoles; Losartan; Male; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Time Factors; Transduction, Genetic; Up-Regulation | 2007 |
[Study of Huoxue Qianyang granules in revising the left ventricular hypertrophy of spontaneous hypertension rats].
Topics: Angiotensin II; Animals; Blood Pressure; Drugs, Chinese Herbal; Heart; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Male; Myocardium; Peptidyl-Dipeptidase A; Phytotherapy; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Gene Expression Regulation; Heart; Homeostasis; Humans; Hypertension; Kidney; Kidney Transplantation; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptor, Angiotensin, Type 1; Sodium | 2006 |
Discoidin domain receptor 1 null mice are protected against hypertension-induced renal disease.
Topics: Angiotensin II; Animals; Chemokine CCL2; Collagen Type I; Collagen Type IV; Cytokines; Discoidin Domain Receptors; Disease Models, Animal; Fibrosis; Hypertension; Inflammation; Kidney Failure, Chronic; Kidney Glomerulus; Lipopolysaccharides; Male; Mice; Mice, Transgenic; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; Shock, Septic; Vasoconstrictor Agents | 2006 |
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7).
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart; Hypertension; Male; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Time Factors; Transforming Growth Factor beta; Ventricular Remodeling | 2007 |
Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Bradykinin; Chronic Disease; Cyclic N-Oxides; Dinoprost; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enalapril; Hydrogen Peroxide; Hypertension; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Spin Labels; Superoxides; Time Factors | 2007 |
Estrogen receptor-alpha mediates estrogen protection from angiotensin II-induced hypertension in conscious female mice.
Topics: Angiotensin II; Animals; Blood Pressure; Consciousness; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; Ganglionic Blockers; Heart Rate; Hypertension; Injections, Intraventricular; Lateral Ventricles; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovariectomy; Vasoconstrictor Agents | 2007 |
A vaccine for hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomedical Research; Clinical Trials as Topic; History, 20th Century; Humans; Hypertension; Renin-Angiotensin System; Vaccines | 2007 |
Activation of NFATc3 down-regulates the beta1 subunit of large conductance, calcium-activated K+ channels in arterial smooth muscle and contributes to hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Cerebral Arteries; Hypertension; Large-Conductance Calcium-Activated Potassium Channels; Mesenteric Arteries; Mice; Mice, Knockout; Muscle, Smooth, Vascular; NFATC Transcription Factors; Signal Transduction | 2007 |
Heme-oxygenase upregulation ameliorates angiotensin II-induced tubulointerstitial injury and salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Cytokines; Heme Oxygenase-1; Hemin; Hypertension; Kidney; Male; Nephritis, Interstitial; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Up-Regulation | 2006 |
Renal denervation attenuates long-term hypertensive effects of Angiotensin ii in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Drinking; Eating; Heart Rate; Hypertension; Kidney; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Sodium; Urodynamics; Water-Electrolyte Balance | 2006 |
Angiotensin in the kidney: a key to understanding hypertension?
Topics: Angiotensin II; Animals; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney; Kidney Transplantation; Mice; Mice, Knockout; Myocardium; Receptor, Angiotensin, Type 1 | 2007 |
Differential sympathetic and angiotensinergic responses in rats submitted to low- or high-salt diet.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Gene Expression Regulation; Hypertension; Kidney; Male; Rats; Rats, Wistar; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride, Dietary; Sympathetic Nervous System | 2007 |
Abnormally increased endothelin-1 in plasma during the night in obstructive sleep apnea: relation to blood pressure and severity of disease.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Case-Control Studies; Endothelin-1; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxygen; Renin; Sleep Apnea, Obstructive | 2007 |
Involvement of Ras-regulated myosin light chain phosphorylation in the captopril effects in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Extracellular Signal-Regulated MAP Kinases; Female; Hypertension; Hypertrophy, Left Ventricular; Male; Mesenteric Arteries; Myosin Light Chains; Phosphorylation; ras Proteins; Rats; Rats, Inbred SHR | 2007 |
Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Arterioles; Gene Expression; Hypertension; Mesenteric Arteries; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Vasodilation | 2007 |
Pressure overload-induced transient oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Fibrosis; Heart Ventricles; Hypertension; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazoles; Time Factors; Ventricular Remodeling | 2006 |
Potential for endothelin-1-mediated impairment of contractile activity in hypertension.
Topics: Aerobiosis; Angiotensin II; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin-1; Hindlimb; Hyperemia; Hypertension; Norepinephrine; Oxygen Consumption; Physical Exertion; Rats; Rats, Wistar; Regional Blood Flow; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2007 |
Investigation of the mechanisms by which chronic infusion of an acutely subpressor dose of angiotensin II induces hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hypertension; Losartan; Receptor, Angiotensin, Type 1; Sheep | 2007 |
Connexin40 is essential for the pressure control of renin synthesis and secretion.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Connexins; Feedback, Physiological; Female; Gap Junction alpha-5 Protein; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Renin | 2007 |
Lack of macrophage migration inhibitory factor regulation is linked to the increased chronotropic action of angiotensin II in SHR neurons.
Topics: Angiotensin II; Animals; Brain Stem; Cells, Cultured; Disease Models, Animal; Female; Hypertension; Hypothalamus; Macrophage Migration-Inhibitory Factors; Male; Neurons; Periodicity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Thrombopoietin | 2007 |
Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II.
Topics: Angiotensin II; Animals; Aorta; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biopterins; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Glutathione Disulfide; Hypertension; Isoenzymes; Male; Mice; Mice, Inbred Strains; Mice, Knockout; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Superoxides; Vasodilation | 2007 |
Vasorelaxant and antioxidant activity of the isoflavone metabolite equol in carotid and cerebral arteries.
Topics: Analysis of Variance; Angiotensin II; Animals; Antioxidants; Blood Pressure; Carotid Arteries; Cerebral Arteries; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Equol; Female; Hypertension; In Vitro Techniques; Isoflavones; Male; Phytoestrogens; Rats; Superoxides; Vasodilation | 2007 |
C-reactive protein causes downregulation of vascular angiotensin subtype 2 receptors and systolic hypertension in mice.
Topics: Angiotensin II; Animals; Benzimidazoles; Benzoates; C-Reactive Protein; Down-Regulation; Hypertension; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Systole; Telmisartan | 2007 |
Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Cardiomegaly; Disease Models, Animal; Half-Life; Hypertension; Imidazoles; Kinetics; Leucine; Male; Mice; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin | 2007 |
ERK activation contributes to regulation of spontaneous contractile tone via superoxide anion in isolated rat aorta of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Butadienes; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Flavonoids; Hypertension; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Superoxides; Vasoconstriction | 2007 |
Renal sympathetic neuroeffector function in renovascular and angiotensin II-dependent hypertension in rabbits.
Topics: Angiotensin II; Animals; Atrophy; Electric Stimulation; Hypertension; Hypertension, Renovascular; Hypertrophy; Kidney; Male; Medulla Oblongata; Neuroeffector Junction; Norepinephrine; Organ Size; Rabbits; Regional Blood Flow; Renin; Sympathetic Nervous System; Vasoconstrictor Agents | 2007 |
Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Antioxidants; Aorta; Arteries; Blood Pressure; Cyclic GMP; Drug Combinations; Hydrogen Peroxide; Hypertension; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride; Vasodilation; Vasodilator Agents | 2007 |
Re-expression of proteins involved in cytokinesis during cardiac hypertrophy.
Topics: Actomyosin; Amides; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Calpain; Cardiomegaly; Cell Nucleus Division; Cullin Proteins; Cytokinesis; Heart; Hypertension; Intracellular Signaling Peptides and Proteins; Mice; Myocytes, Cardiac; Myofibrils; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred Dahl; rho GTP-Binding Proteins; rho-Associated Kinases; Up-Regulation | 2007 |
Role of connective tissue growth factor in vascular and renal damage associated with hypertension in rats. Interactions with angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Connective Tissue Growth Factor; Fibrosis; Hypertension; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Cortex; Male; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2006 |
Effects of angiotensin 1-7 on the actions of angiotensin II in the renal and mesenteric vasculature of hypertensive and streptozotocin-induced diabetic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypertension; Kidney; Male; Nitric Oxide; Peptide Fragments; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Splanchnic Circulation; Streptozocin | 2007 |
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output, Low; Drug Synergism; Eplerenone; Hypertension; Indoles; Kidney; Male; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Spironolactone; Superoxide Dismutase; Transforming Growth Factor beta | 2007 |
Fos-related antigen immunoreactivity after acute and chronic angiotensin II-induced hypertension in the rabbit brain.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Drug Administration Schedule; Hypertension; Immunohistochemistry; Male; Proto-Oncogene Proteins c-fos; Rabbits; Time Factors; Tissue Distribution; Vasoconstrictor Agents | 2007 |
The effects of angiotensin II and genetic hypertension upon extracellular nucleotide hydrolysis by rat platelet ectoenzymes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Angiotensin II; Animals; Blood Platelets; Enzyme Activation; Hydrolysis; Hypertension; Male; Phenotype; Phosphoric Diester Hydrolases; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Thymidine Monophosphate; Vasoconstrictor Agents | 2007 |
Synergistic vascular protective effects of combined low doses of PPARalpha and PPARgamma activators in angiotensin II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Drug Synergism; Hypertension; Male; NADPH Oxidases; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley | 2007 |
Effects of Qindan Capsule on blood pressure, endothelin, calcitonin gene-related peptide and angiotensin- II in spontaneous hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsules; Endothelins; Hypertension; Male; Medicine, Chinese Traditional; Mesenteric Arteries; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2006 |
Angiotensin II-induced sudden arrhythmic death and electrical remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cardiac Pacing, Artificial; Cardiomegaly; Connexin 43; Death, Sudden, Cardiac; Disease Models, Animal; Electrocardiography; Heart Conduction System; Hypertension; Losartan; Male; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Shal Potassium Channels; Tachycardia, Ventricular; Telemetry; Time Factors; Ventricular Remodeling | 2007 |
Changes in the subcellular distribution of NADPH oxidase subunit p47phox in dendrites of rat dorsomedial nucleus tractus solitarius neurons in response to chronic administration of hypertensive agents.
Topics: Angiotensin II; Animals; Blood Pressure; Dendrites; Hypertension; Immunoenzyme Techniques; Immunohistochemistry; Male; Microscopy, Electron; NADPH Oxidases; Neurons; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Solitary Nucleus; Subcellular Fractions; Sympathomimetics | 2007 |
CD59 or C3 are not requred for angiotensin II-dependent hypertension or hypertrophy in mice.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Body Weight; Cardiomegaly; CD59 Antigens; Complement Activation; Complement C3; Cyclic GMP; Dose-Response Relationship, Drug; Hypertension; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Platelet Endothelial Cell Adhesion Molecule-1; Receptor, Angiotensin, Type 1; Tissue Culture Techniques | 2007 |
Genetic and dietary interactions: role of angiotensin AT1a receptors in response to a high-fructose diet.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Circadian Rhythm; Dietary Carbohydrates; Disease Models, Animal; Fructose; Glucose Intolerance; Heart Rate; Hypertension; Insulin Resistance; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prazosin; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System; Time Factors | 2007 |
[Hypertension and the renin-angiotensin-aldosterone pathway].
Topics: Angiotensin II; Humans; Hypertension; Renin-Angiotensin System | 2007 |
Developmental activity of the renin-angiotensin system during the "critical period" modulates later L-NAME-induced hypertension and renal injury.
Topics: Aging; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Cardiovascular System; Critical Period, Psychological; Drug Administration Schedule; Enzyme Inhibitors; Hypertension; Kidney; Male; Mortality; NG-Nitroarginine Methyl Ester; Oxidative Stress; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Tetrazoles; Vasoconstrictor Agents | 2007 |
Angiotensin II-based hypertension and the sympathetic nervous system: the role of dose and increased dietary salt in rabbits.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Ganglionic Blockers; Hypertension; Kidney; Pentolinium Tartrate; Rabbits; Sodium Chloride, Dietary; Sympathectomy, Chemical; Sympathetic Nervous System; Vasoconstrictor Agents | 2007 |
Early left ventricular gene expression profile in response to increase in blood pressure.
Topics: Acute Disease; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arginine Vasopressin; bcl-X Protein; Blood Pressure; Cell Cycle Proteins; Chronic Disease; Consciousness; DNA, Complementary; Early Growth Response Protein 1; Eye Proteins; Fatty Acid-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Heart Ventricles; HSP70 Heat-Shock Proteins; Hypertension; Losartan; Male; Nerve Growth Factor; Nerve Tissue Proteins; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Autoantibodies against G-protein-coupled receptors modulate heart mast cells.
Topics: Adrenergic alpha-Agonists; Adult; Angiotensin II; Animals; Animals, Newborn; Autoantibodies; Cell Degranulation; Cell Differentiation; Cells, Cultured; Female; Humans; Hypertension; Hypertension, Pulmonary; Male; Mast Cells; Middle Aged; Myocardium; Phenylephrine; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Receptors, G-Protein-Coupled; Time Factors | 2007 |
NOX1 deficiency protects from aortic dissection in response to angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Disease Susceptibility; Gene Expression Regulation; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 1; NADPH Oxidases; Norepinephrine; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Vasoconstrictor Agents | 2007 |
Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation.
Topics: Aldosterone; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Body Weight; Cytokines; Disease Models, Animal; Eplerenone; Female; Fibroblasts; Fibrosis; Hypertension; Immunohistochemistry; In Situ Hybridization; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Inbred BALB C; Mineralocorticoid Receptor Antagonists; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; Spironolactone; Tenascin; Up-Regulation; Vasoconstrictor Agents | 2007 |
Role of matrix metalloproteinases in early hypertensive vascular remodeling.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Carotid Arteries; Compliance; Enzyme Activation; Hypertension; In Vitro Techniques; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Tunica Media; Vasoconstrictor Agents | 2007 |
Effect of chronic IL-6 infusion on acute pressor responses to vasoconstrictors in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Heart Rate; Hypertension; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pressoreceptors; Vasoconstrictor Agents | 2007 |
Gender differences in vascular disease: not a simple explanation.
Topics: Angiotensin II; Animals; Female; Humans; Hypertension; Male; Mice; NADPH Oxidases; Sex Characteristics; Thioredoxins; Vascular Diseases | 2007 |
Differential regulation of thioredoxin and NAD(P)H oxidase by angiotensin II in male and female mice.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Sex Characteristics; Thioredoxins | 2007 |
Genetic disruption of guanylyl cyclase/natriuretic peptide receptor-A upregulates ACE and AT1 receptor gene expression and signaling: role in cardiac hypertrophy.
Topics: Angiotensin II; Animals; Captopril; Cardiomegaly; Cyclic GMP; Fibrosis; Gene Expression Regulation; Guanylate Cyclase; Heart Ventricles; Hydralazine; Hypertension; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Atrial Natriuretic Factor; Renin-Angiotensin System; Signal Transduction; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2007 |
Mycophenolate mofetil administration reduces renal inflammation, oxidative stress, and arterial pressure in rats with lead-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Creatinine; Hypertension; Immunosuppressive Agents; Inflammation; Kidney Diseases; Lead; Lymphocytes; Macrophages; Male; Malondialdehyde; Mycophenolic Acid; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Superoxides; Transcription Factor RelA | 2007 |
Effects of p38 MAPK Inhibitor on angiotensin II-dependent hypertension, organ damage, and superoxide anion production.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Carotid Arteries; Echocardiography; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Imidazoles; Intracellular Signaling Peptides and Proteins; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Myocardium; NADPH Oxidase 2; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Protein Kinases; Protein Serine-Threonine Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilation; Ventricular Remodeling | 2007 |
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage.
Topics: Albuminuria; Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Humans; Hypertension; I-kappa B Proteins; Inflammation; Intercellular Adhesion Molecule-1; Kidney Diseases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Cardiovascular; Nephritis; NF-kappa B; NF-KappaB Inhibitor alpha; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Specificity; Receptor, TIE-1; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2007 |
Cardiac BNP gene activation by angiotensin II in vivo.
Topics: Angiotensin II; Animals; Body Weight; Cells, Cultured; DNA; GATA4 Transcription Factor; GATA6 Transcription Factor; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Transgenic; Myocardium; Natriuretic Peptide, Brain; Organ Size; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-ets; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA, Messenger; Transcription Factor AP-1; Transcriptional Activation | 2007 |
Classic interleukin-6 receptor signaling and interleukin-6 trans-signaling differentially control angiotensin II-dependent hypertension, cardiac signal transducer and activator of transcription-3 activation, and vascular hypertrophy in vivo.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Hypertension; Hypertrophy; Interleukin-6; Mice; Myocardium; Receptors, Interleukin-6; Recombinant Fusion Proteins; Signal Transduction; STAT3 Transcription Factor; Transcriptional Activation | 2007 |
Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Kidney; Rats; Rats, Inbred WKY; Renal Circulation; Renin-Angiotensin System; Sulfhydryl Compounds; Time Factors | 2007 |
Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function.
Topics: Angiotensin I; Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Erectile Dysfunction; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Sodium Chloride, Dietary; Vasodilator Agents | 2007 |
An intact median preoptic nucleus is necessary for chronic angiotensin II-induced hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Drinking; Heart Rate; Hypertension; Male; Preoptic Area; Rats; Rats, Sprague-Dawley; Sodium | 2007 |
Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Base Sequence; Calcium; DNA Primers; Guanine Nucleotide Exchange Factors; Hypertension; Immunoprecipitation; Mesenteric Arteries; Myosin-Light-Chain Phosphatase; Protein Transport; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; Signal Transduction | 2007 |
PPAR-gamma activation inhibits angiotensin II synthesis, apoptosis, and proliferation of mesangial cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Hypertension; Mesangial Cells; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones | 2007 |
Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Congenic; Blood Pressure; C-Reactive Protein; Cell Adhesion Molecules; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Membrane Proteins; Ovariectomy; Peptide Fragments; Proteinuria; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 2007 |
Regulator of G protein signalling 2 ameliorates angiotensin II-induced hypertension in mice.
Topics: Angiotensin II; Animals; Arterioles; Baroreflex; Blood Pressure; Disease Models, Animal; Endothelin-1; Epinephrine; Heart Rate; Hypertension; Male; Mice; Mice, Knockout; Norepinephrine; Phenylephrine; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RGS Proteins; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Increased hypothalamic angiotensin-(1-7) levels in rats with aortic coarctation-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Aortic Coarctation; Hypertension; Hypothalamus; Kidney; Male; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System | 2007 |
Splanchnic circulation is a critical neural target in angiotensin II salt hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Ganglia, Sympathetic; Ganglionectomy; Hypertension; Kidney; Male; Radio Waves; Rats; Rats, Sprague-Dawley; Sodium Chloride; Splanchnic Circulation; Telemetry; Vasoconstrictor Agents; Vasomotor System | 2007 |
Internal mammary artery grafts reactivity in hypertensive patients: role of stretching in extraendothelial nitric oxide.
Topics: Aged; Angiotensin II; Biomechanical Phenomena; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Hypertension; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Potassium Chloride; Stress, Mechanical; Vasodilation | 2007 |
The effect of diet on simvastatin and losartan enhancement of endothelial function.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diet; Diet, Sodium-Restricted; Dietary Fats; Endothelium, Vascular; Epoprostenol; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Kidney; Lipids; Losartan; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Simvastatin; Sodium, Dietary; Superoxides; Thromboxane A2 | 2007 |
Angiotensin II chronic infusion induces B1 receptor expression in aorta of rats.
Topics: Acetophenones; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Infusion Pumps, Implantable; Male; NADPH Oxidases; NF-kappa B; Nitric Oxide; Rats; Rats, Wistar; Receptor, Bradykinin B1; Superoxides | 2007 |
[Peroxisome proliferator-activated receptor activator troglitazone inhibits angiotensin II-stimulated secretion of vasoactive factors by endothelial cells].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cell Line; Chromans; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin-1; Gene Expression Regulation; Humans; Hypertension; Immunohistochemistry; Losartan; Nitric Oxide; PPAR gamma; Receptor, Angiotensin, Type 1; Thiazolidinediones; Troglitazone | 2007 |
Endothelial NF-kappaB as a mediator of kidney damage: the missing link between systemic vascular and renal disease?
Topics: Albuminuria; Angiotensin II; Animals; Atherosclerosis; Endothelium, Vascular; Fibrosis; Gemfibrozil; Humans; Hypertension; I-kappa B Proteins; Inflammation; Kidney Diseases; Mice; Models, Cardiovascular; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Specificity; Sodium Chloride, Dietary | 2007 |
Inflammation in the genesis of hypertension and its complications--the role of angiotensin II.
Topics: Angiotensin II; Anti-Inflammatory Agents; C-Reactive Protein; Cytokines; Humans; Hypertension; Inflammation | 2007 |
Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.
Topics: Angiotensin II; Animals; Base Sequence; Blood Pressure; Dinoprostone; Hypertension; Male; Mice; Mice, Transgenic; Protein Kinase C; Rats; Rats, Inbred SHR; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype | 2007 |
Chronic alcohol-induced oxidative endothelial injury relates to angiotensin II levels in the rat.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Endothelium, Vascular; Ethanol; Glutathione; Hypertension; Male; Malondialdehyde; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred F344; Time Factors; Vascular Endothelial Growth Factor A | 2008 |
Inhibition of renal dipeptidyl peptidase IV enhances peptide YY1-36-induced potentiation of angiotensin II-mediated renal vasoconstriction in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Hypertension; Kidney; Male; Peptide YY; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 2007 |
Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; Cell Movement; Hypertension; Lymphocyte Activation; Mice; Mice, Knockout; NADPH Oxidases; T-Lymphocytes; Vascular Diseases | 2007 |
Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine.
Topics: Acetophenones; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Cardiomegaly; Carotid Arteries; Cyclic N-Oxides; Hydralazine; Hypertension; Hypolipidemic Agents; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Simvastatin; Spin Labels; Superoxides; Tunica Media | 2007 |
Spotlight on renin. Mechanisms of hypertension-induced target organ damage.
Topics: Angiotensin II; Animals; Blood Vessels; Death, Sudden; Heart Diseases; Humans; Hypertension; Immune System; Kidney; Kidney Diseases; NF-kappa B; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System | 2007 |
Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse.
Topics: Aldosterone; Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Cardiomegaly; Diet, Atherogenic; Disease Models, Animal; Fenofibrate; Genotype; Humans; Hypertension; Hypolipidemic Agents; Mice; Mice, Knockout; Mice, Transgenic; PPAR alpha; Renin; Renin-Angiotensin System | 2007 |
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.
Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Biopterins; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Endothelium, Vascular; Heart Failure, Diastolic; Hydralazine; Hypertension; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilation | 2007 |
Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.
Topics: Angiotensin II; Animals; Chemokine CCL2; Collagen; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Hypertension; Intercellular Adhesion Molecule-1; Kidney; Macrophages; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Receptors, CCR2; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha | 2007 |
Renal interstitial adenosine is increased in angiotensin II-induced hypertensive rats.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney Cortex; Male; Proteinuria; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Vasoconstrictor Agents | 2008 |
[Increased plasma vasoactive substances and antioxidant enzymes levels in prehypertensive patients].
Topics: Adult; Angiotensin II; Antioxidants; Blood Pressure; Calcitonin Gene-Related Peptide; Case-Control Studies; Endothelins; Female; Glutathione Peroxidase; Humans; Hypertension; Male; Middle Aged; Nitric Oxide Synthase; Plasma; Superoxide Dismutase; Vasopressins | 2007 |
A proteomic analysis of aorta from spontaneously hypertensive rat: RhoGDI alpha upregulation by angiotensin II via AT(1) receptor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Guanine Nucleotide Dissociation Inhibitors; Hypertension; Imidazoles; Male; Muscle, Smooth, Vascular; Proteomics; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; rho-Specific Guanine Nucleotide Dissociation Inhibitors; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazoles; Up-Regulation; Vasoconstrictor Agents | 2008 |
The neurovascular dysfunction induced by angiotensin II in the mouse neocortex is sexually dimorphic.
Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Disease Susceptibility; Estradiol; Estrogen Replacement Therapy; Female; Hypertension; Infusion Pumps, Implantable; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Neocortex; Ovariectomy; Reflex; Sex Factors; Stroke; Time Factors; Vasodilator Agents; Vibrissae | 2008 |
Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension.
Topics: Actins; Adenosine Triphosphate; Angiotensin II; Animals; Arterioles; Blood Pressure; Cell Proliferation; Clopidogrel; Disease Models, Animal; Hypertension; Hypertrophy; Kidney; Male; Membrane Proteins; Mesangial Cells; Purinergic Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Renin; Ticlopidine | 2008 |
Targeting NAD(P)H oxidase: Ets-1 regulates p47(phox).
Topics: Angiotensin II; Animals; Humans; Hypertension; NADPH Oxidases; Proto-Oncogene Protein c-ets-1; Reactive Oxygen Species | 2007 |
Ultrastructural islet study of early fibrosis in the Ren2 rat model of hypertension. Emerging role of the islet pancreatic pericyte-stellate cell.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Glucose; Blood Pressure; Body Weight; Cell Communication; Disease Models, Animal; Extracellular Matrix; Fibrosis; Hypertension; Islets of Langerhans; Male; Oxidative Stress; Pericytes; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2007 |
Rapid development of severe end-organ damage in C57BL/6 mice by combining DOCA salt and angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Disease Models, Animal; Hypertension; Kidney Failure, Chronic; Kidney Glomerulus; Male; Mice; Mineralocorticoids; Myocardium; Proteinuria; Vasoconstrictor Agents | 2008 |
Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP11B2; Female; Hyperaldosteronism; Hypertension; Male; Mice; Mice, Mutant Strains; Nitric Oxide; Oxidative Stress; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium; Sodium, Dietary; Vasoconstrictor Agents | 2008 |
Positive correlation between chymase-like angiotensin II-forming activity in mononuclear cells and serum cholesterol level.
Topics: Angiotensin II; Arteriosclerosis; Cholesterol; Chymases; Humans; Hypertension; Leukocytes, Mononuclear; Middle Aged; Risk Factors; Smoking | 2007 |
Linking inflammation and hypertension in humans: studies in Bartter's/Gitelman's syndrome patients.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Bartter Syndrome; Blotting, Western; Case-Control Studies; eIF-2 Kinase; Female; Gitelman Syndrome; Humans; Hypertension; Inflammation; Male; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1 | 2008 |
Pressor and non-pressor effects of sodium loading on stroke in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Brain; Disease Models, Animal; Female; Heart Rate; Hypertension; Interleukin-1beta; Interleukin-6; Intracranial Aneurysm; Rats; Rats, Inbred SHR; Regression Analysis; Sodium Chloride, Dietary; Stroke; Time Factors; Tumor Necrosis Factor-alpha | 2008 |
Prevention of hypertension, cardiovascular damage and endothelial dysfunction with green tea extracts.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Camellia sinensis; Cardiovascular Diseases; Endothelium, Vascular; Heart Rate; Heme Oxygenase-1; Hypertension; Male; NADPH Oxidases; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides | 2007 |
Noradrenaline and angiotensin II modify vascular prostanoid release in fructose-fed hypertensive rats.
Topics: Angiotensin II; Animals; Endothelium, Vascular; Fructose; Hypertension; Male; Mesentery; Norepinephrine; Prostaglandins; Rats; Rats, Sprague-Dawley | 2007 |
[Study on the correlation between hypertension and the indexes of vascular endothelial function among people living in the community].
Topics: Adult; Age Factors; Aged; Angiotensin II; Cluster Analysis; Endothelium, Vascular; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Obesity; Overweight; Prevalence; Risk Factors | 2007 |
Omega-3 polyunsaturated fatty acid supplementation reduces hypertension in TGR(mRen-2)27 rats.
Topics: Adipose Tissue; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Eating; Fatty Acids, Omega-3; Hypertension; Male; Perindopril; Rats; Renin | 2008 |
Upregulation of cortical COX-2 in salt-sensitive hypertension: role of angiotensin II and reactive oxygen species.
Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Gene Expression; Hypertension; Kidney Cortex; Kidney Medulla; Male; Membrane Proteins; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sodium Chloride, Dietary; Spin Labels; Tetrazoles; Up-Regulation | 2008 |
Genes overexpressed in cerebral arteries following salt-induced hypertensive disease are regulated by angiotensin II, JunB, and CREB.
Topics: Algorithms; Angiotensin II; Animals; Blotting, Western; Cell Proliferation; Cerebral Arteries; Cerebrovascular Circulation; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Hypertension; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-jun; Rats; Rats, Inbred Dahl; RNA; RNA, Small Interfering; Sodium Chloride, Dietary; Transfection; Up-Regulation | 2008 |
Angiotensin II: one driving force behind atherogenesis.
Topics: Angiotensin II; Animals; Atherosclerosis; Desoxycorticosterone; Humans; Hypertension; Sodium Chloride | 2008 |
Deoxycorticosterone acetate salt hypertension in apolipoprotein E-/- mice results in accelerated atherosclerosis: the role of angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Vessels; Desoxycorticosterone; Hypertension; Mice; Mice, Knockout; Renin-Angiotensin System; Sodium Chloride; Time Factors | 2008 |
Vaccine takes aim at hypertension.
Topics: Angiotensin II; Humans; Hypertension; Immunotherapy, Active; Oligopeptides; Vaccines, Synthetic | 2007 |
A novel adipokine CTRP1 stimulates aldosterone production.
Topics: Adipokines; Aldosterone; Angiotensin II; Animals; Calcium; Cytochrome P-450 CYP11B2; DNA-Binding Proteins; Humans; Hypertension; Losartan; Male; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured | 2008 |
AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension.
Topics: A Kinase Anchor Proteins; Angiotensin II; Animals; Calcium Channels, L-Type; Calcium Signaling; Hypertension; Mice; Mice, Knockout; Protein Kinase C-alpha; Vascular Resistance | 2008 |
Heme oxygenase-1 induction does not improve vascular relaxation in angiotensin II hypertensive mice.
Topics: Angiotensin II; Animals; Aorta; Drug Interactions; Endothelium, Vascular; Enzyme Activation; Heme Oxygenase-1; Hypertension; Male; Mice; Mice, Inbred C57BL; Protoporphyrins; Vasoconstrictor Agents; Vasodilation | 2008 |
Novel anti-inflammatory mechanisms of N-Acetyl-Ser-Asp-Lys-Pro in hypertension-induced target organ damage.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Azo Compounds; Blotting, Western; Cardiomegaly; Cell Separation; Collagen; Fibrosis; Galectin 3; Heart Rate; Hypertension; In Vitro Techniques; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Myocardium; Neutrophil Infiltration; Oligopeptides; Stem Cells; Tumor Necrosis Factor-alpha | 2008 |
Renal redox-sensitive signaling, but not blood pressure, is attenuated by Nox1 knockout in angiotensin II-dependent chronic hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; CSK Tyrosine-Protein Kinase; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hypertension; Kidney; Male; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Procollagen; Protein Isoforms; Protein-Tyrosine Kinases; Renin; Signal Transduction; src-Family Kinases; Systole; Vascular Cell Adhesion Molecule-1 | 2008 |
Angiotensin II infusion induces nephrin expression changes and podocyte apoptosis.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Creatinine; Hypertension; In Situ Nick-End Labeling; Male; Membrane Proteins; Podocytes; Proteinuria; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2008 |
Pravastatin attenuates left ventricular remodeling and diastolic dysfunction in angiotensin II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cholesterol; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Failure, Diastolic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Pravastatin; rho-Associated Kinases; Ventricular Remodeling | 2008 |
The perinatal development of arterial pressure in sheep: effects of low birth weight due to twinning.
Topics: Angiotensin II; Animals; Birth Weight; Blood Pressure; Female; Fetal Development; Heart Rate; Hydrocortisone; Hypertension; Male; Pregnancy; Pregnancy, Animal; Renin; Sex Factors; Sheep; Twins; Water-Electrolyte Balance | 2008 |
Hyperinsulinemic rats are normotensive but sensitized to angiotensin II.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Disease Models, Animal; Female; Ganglia, Sympathetic; Ganglionic Blockers; Glucose; Heart Rate; Hexamethonium; Hyperinsulinism; Hypertension; Insulin; Insulin Infusion Systems; Losartan; Myography; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Telemetry; Time Factors; Vasodilation; Vasodilator Agents | 2008 |
Sympathetic nerve activity in the superior cervical ganglia increases in response to imposed increases in arterial pressure.
Topics: Action Potentials; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Catheterization; Cerebral Arteries; Cerebral Veins; Cerebrovascular Circulation; Disease Models, Animal; Epinephrine; Humans; Hypertension; Hypotension; Male; Microelectrodes; Nitroprusside; Phenylephrine; Sheep; Superior Cervical Ganglion; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling.
Topics: Amides; Angiotensin II; Animals; Blood Pressure; Fumarates; Humans; Hypertension; Muscle, Smooth, Vascular; Oligopeptides; Rats; Renin | 2008 |
Kidney fibrosis in hypertensive rats: role of oxidative stress.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Blotting, Western; Collagen; Fibrosis; Gene Expression; Hypertension; Immunohistochemistry; In Situ Hybridization; Kidney; Male; Myofibrils; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta1; Up-Regulation | 2008 |
Pioglitazone opposes neurogenic vascular dysfunction associated with chronic hyperinsulinaemia.
Topics: Administration, Oral; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Chronic Disease; Disease Models, Animal; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Norepinephrine; Pioglitazone; Random Allocation; Rats; Rats, Wistar; Thiazolidinediones; Triglycerides; Vasoconstriction | 2008 |
Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; NADPH Oxidases; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; src-Family Kinases; Superoxides; Type C Phospholipases; Vasoconstriction | 2008 |
Whole body norepinephrine kinetics in ANG II-salt hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Heart Rate; Hypertension; Infusion Pumps, Implantable; Kinetics; Male; Norepinephrine; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sympathetic Nervous System; Tritium | 2008 |
Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcium-Binding Proteins; Calpain; Cysteine Proteinase Inhibitors; Disease Models, Animal; Fibrosis; Genetic Therapy; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Inflammation; Infusion Pumps, Implantable; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocardium; NF-kappa B; NFATC Transcription Factors; Renal Artery; Time Factors; Ventricular Remodeling | 2008 |
Angiotensin II upregulates LDL receptor-related protein (LRP1) expression in the vascular wall: a new pro-atherogenic mechanism of hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atherosclerosis; Cells, Cultured; Cholesterol Esters; Disease Models, Animal; Humans; Hypertension; Imidazoles; Lactoferrin; Losartan; Low Density Lipoprotein Receptor-Related Protein-1; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Up-Regulation | 2008 |
Glutathione peroxidase-1 plays a major role in protecting against angiotensin II-induced vascular dysfunction.
Topics: Acetylcholine; Angiotensin II; Animals; Carotid Arteries; Catalase; Endothelium, Vascular; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hydrogen Peroxide; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Oxidative Stress; Polyethylene Glycols; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Effects of extended-release felodipine on endothelial vasoactive substances in patients with essential hypertension.
Topics: Angiotensin II; Colorimetry; Delayed-Action Preparations; Endothelins; Endothelium, Vascular; Epoprostenol; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase | 2008 |
Hypothetical mechanism of sodium pump regulation by estradiol under primary hypertension.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Estradiol; Humans; Hypertension; Male; Mitogen-Activated Protein Kinases; Models, Cardiovascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Rats; Rats, Wistar; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase | 2008 |
Absence of vascular remodelling in a high angiotensin-II state (Bartter's and Gitelman's syndromes): implications for angiotensin II signalling pathways.
Topics: Adult; Angiotensin II; Bartter Syndrome; Carotid Arteries; Endothelium, Vascular; Female; Gitelman Syndrome; Humans; Hypertension; Male; Middle Aged; Receptors, Drug; Signal Transduction; Solute Carrier Family 12, Member 3; Symporters; Tunica Intima; Tunica Media; Ultrasonography; Vasodilation; Young Adult | 2008 |
Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estradiol; Female; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovariectomy; Phenylephrine; Rats; Rats, Sprague-Dawley; Renin; Serotonin; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Inhibition of vascular angiotensin-converting enzyme by telmisartan via the peroxisome proliferator-activated receptor gamma agonistic property in rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Carotid Arteries; Disease Models, Animal; Hypertension; Male; NADPH Oxidases; Peptidyl-Dipeptidase A; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilation; Vasodilator Agents | 2007 |
Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Case-Control Studies; Cells, Cultured; Disease Models, Animal; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Linkage Disequilibrium; Male; Mice; Mice, Inbred C57BL; Middle Aged; Muscle Proteins; Myocytes, Cardiac; Polymorphism, Single Nucleotide; Rats; Rats, Sprague-Dawley; Ultrasonography; Vasoconstrictor Agents | 2007 |
Angiotensin II induces the vascular expression of VEGF and MMP-2 in vivo: preventive effect of red wine polyphenols.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Hypertension; Male; Matrix Metalloproteinase 2; Metalloporphyrins; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Peroxynitrous Acid; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A; Wine | 2008 |
Effect of perindopril on renal medullary blood flow: comparison with other antihypertensive treatments.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Kidney Medulla; Male; Nitric Oxide; Perindopril; Rats | 2008 |
Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Disease Models, Animal; Hypertension; Male; Myocardium; Peptide Fragments; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Time Factors | 2008 |
Aminopeptidase A: could it be a novel target for neurogenic hypertension?
Topics: Angiotensin II; Angiotensin III; Animals; Blood Pressure; Blood-Brain Barrier; Disease Models, Animal; Enzyme Inhibitors; Glutamyl Aminopeptidase; Humans; Hypertension; Rats; Renin-Angiotensin System; Sulfonic Acids | 2008 |
Blood pressure lowering effects of niacin-bound chromium(III) (NBC) in sucrose-fed rats: renin-angiotensin system.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Chromium; Female; Hypertension; Male; Nicotinic Acids; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sucrose; Systole | 2008 |
Effects of maternal undernutrition on renal angiotensin II and chymase in hypertensive offspring.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Chymases; Disease Models, Animal; Female; Hypertension; Kidney; Kidney Glomerulus; Malnutrition; Organ Size; Peptidyl-Dipeptidase A; Placenta; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Reference Values | 2008 |
Nitric oxide deficiency and increased adenosine response of afferent arterioles in hydronephrotic mice with hypertension.
Topics: Adenosine; Angiotensin II; Animals; Arterioles; Disease Models, Animal; Enzyme Inhibitors; Hydronephrosis; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Superoxide Dismutase; Superoxide Dismutase-1; Transforming Growth Factors; Vasoconstriction; Vasoconstrictor Agents | 2008 |
H2O2 stimulation of the Cl-/HCO3- exchanger by angiotensin II and angiotensin II type 1 receptor distribution in membrane microdomains.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Cell Membrane; Cells, Cultured; Chloride-Bicarbonate Antiporters; Epithelial Cells; Hydrogen Peroxide; Hypertension; Kidney Tubules, Proximal; Membrane Microdomains; NADPH Oxidases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Signal Transduction | 2008 |
Involvement of tumor necrosis factor-alpha in angiotensin II-mediated effects on salt appetite, hypertension, and cardiac hypertrophy.
Topics: Angiotensin II; Animals; Appetite; Blood Pressure; Cardiomegaly; Heart; Hypertension; Male; Mice; Mice, Knockout; NF-kappa B; Receptor, Angiotensin, Type 1; Sodium Chloride; Thirst; Tumor Necrosis Factor-alpha | 2008 |
Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme 2; Cell Line; Female; Gene Expression Regulation; Humans; Hypertension; Hypertension, Renal; Kidney; Male; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Signal Transduction | 2008 |
Effect of total flavonoid fraction of Astragalus complanatus R. Brown on angiotensin II-induced portal-vein contraction in hypertensive rats.
Topics: Angiotensin II; Animals; Astragalus Plant; Flavonoids; Hypertension; Male; Muscle Contraction; Portal Vein; Rats; Rats, Inbred SHR; Rats, Wistar | 2008 |
Prevention of salt-induced hypertension and fibrosis by AT1-receptor blockers in Dahl S rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Benzoates; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Fibrosis; Heart Rate; Hypertension; Hypertrophy; Kidney; Losartan; Male; Myocardium; Organ Specificity; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium, Dietary; Telmisartan | 2008 |
Reduced levels of cyclic AMP contribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Angiotensin II; Animals; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Activators; Hypertension; Isoproterenol; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides | 2008 |
Ste20-related kinase SLK phosphorylates Ser188 of RhoA to induce vasodilation in response to angiotensin II Type 2 receptor activation.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Casein Kinase II; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Ethinyl Estradiol; Hypertension; Male; Megestrol Acetate; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; rhoA GTP-Binding Protein; Signal Transduction; Up-Regulation; Vasoconstrictor Agents; Vasodilation | 2008 |
SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Hypertension; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Niacinamide; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Resveratrol; RNA, Messenger; Sirtuin 1; Sirtuins; Sp1 Transcription Factor; Stilbenes; Time Factors; Transcription, Genetic; Transfection | 2008 |
Angiotensin II increases GABAB receptor expression in nucleus tractus solitarii of rats.
Topics: Action Potentials; Angiotensin II; Animals; Animals, Newborn; Baclofen; Baroreflex; Blood Pressure; Blotting, Western; Cells, Cultured; Disease Models, Animal; GABA Agonists; GABA-B Receptor Agonists; Hypertension; Infusions, Parenteral; Male; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, GABA-A; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solitary Nucleus; Time Factors; Up-Regulation | 2008 |
Alpha2-antiplasmin is a critical regulator of angiotensin II-mediated vascular remodeling.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Collagen Type I; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Eye Proteins; Fibrosis; Gelatinases; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Growth Factors; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Serpins; Thoracic Arteries; Tumor Suppressor Protein p53 | 2008 |
Sex differences in circulating and renal angiotensins of hypertensive mRen(2). Lewis but not normotensive Lewis rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Blood Pressure; Disease Models, Animal; Female; Hypertension; Kidney; Male; Mice; Myocardium; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sex Factors | 2008 |
Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, alphavbeta3-integrin, and TGF-beta1 in response to ANG II and high glucose.
Topics: Acetates; Angiotensin II; Animals; Antibodies; Benzodiazepinones; Blood Glucose; Blood Pressure; Cells, Cultured; Collagen Type I; Diabetes Mellitus, Experimental; Elasticity; Fibrosis; Hypertension; Integrin alphaVbeta3; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Microcirculation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; RNA Interference; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1 | 2008 |
Novel role for inhibitor of differentiation 2 in the genesis of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Cells; Bone Marrow Transplantation; Hypertension; Immune System; Inhibitor of Differentiation Protein 2; Kidney Transplantation; Mice; Mice, Knockout; Mice, Transgenic | 2008 |
A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.
Topics: Angiotensin II; Animals; Captopril; Disease Models, Animal; Gene Expression Regulation; Hypertension; Intellectual Disability; Kidney; Mice; Mutation; Phenotype; ras Proteins; Recombination, Genetic; Signal Transduction; Syndrome | 2008 |
Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Cardiomegaly; Cell Proliferation; Cytoskeleton; Disease Models, Animal; Hypertension; Immunosuppressive Agents; Interferon-gamma; Kidney Diseases; Male; Mice; Mice, Knockout; Mycophenolic Acid; Sodium Chloride, Dietary; T-Lymphocytes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2008 |
Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Hypertension; Male; Rats; Rats, Wistar; Sodium; Sympathetic Nervous System | 2008 |
Upregulation of interleukin-8/CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Hypertension; Interleukin-8; Losartan; Male; Muscle, Smooth, Vascular; NF-kappa B; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Signal Transduction; Transfection; Up-Regulation; Vasoconstrictor Agents | 2008 |
Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Blood Pressure; Carotid Arteries; Catheterization; Disease Models, Animal; Heart Rate; Hyperplasia; Hypertension; Imidazoles; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tunica Intima | 2008 |
Nitrendipine reverses vasoconstriction and renal hemodynamic changes in experimental hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Hypertension; Male; Nifedipine; Nitrendipine; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Renal Circulation; Sodium; Time Factors; Vasoconstriction | 1984 |
Na+,K+-ATPase activity and responsiveness of vascular smooth muscle to norepinephrine, angiotensin II and calcium ionophore A23187 in guinea pig aortic strips.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcimycin; Calcium; Guinea Pigs; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Sodium-Potassium-Exchanging ATPase; Vasoconstriction | 1984 |
Renin- and non-renin-mediated antihypertensive actions of converting enzyme inhibitors.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Drug Therapy, Combination; Humans; Hypertension; Male; Proline; Prostaglandins; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1984 |
Hormonal and metabolic effects of angiotensin converting enzyme inhibitors. Possible differences between enalapril and captopril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dipeptides; Enalapril; Humans; Hypertension; Kinins; Posture; Potassium; Proline; Prostaglandins; Renin; Renin-Angiotensin System; Sodium | 1984 |
Enalapril in treatment of hypertension with renal artery stenosis. Changes in blood pressure, renin, angiotensin I and II, renal function, and body composition.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Body Composition; Creatinine; Dipeptides; Drug Evaluation; Enalapril; Female; Heart Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Posture; Potassium; Renal Artery Obstruction; Renin; Sodium | 1984 |
Angiotensin II receptors in the brain and adrenal glands of rats with experimental and spontaneous hypertension.
Topics: Adrenal Glands; Angiotensin II; Animals; Brain Chemistry; Hypertension; Hypertension, Renal; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Receptors, Cell Surface | 1984 |
[Changes in responses of blood pressure and several hormones to infusions of angiotensin II and angiotensin III in patients with essential hypertension].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Catecholamines; Glomerular Filtration Rate; Hormones; Humans; Hydrocortisone; Hypertension; Male; Renin | 1984 |
Increased angiotensin II receptors in neuronal cultures from hypertensive rat brain.
Topics: alpha-Methyltyrosine; Angiotensin II; Animals; Binding Sites; Brain; Cells, Cultured; Dopamine; Hypertension; Iodine Radioisotopes; Kinetics; Methyltyrosines; Neurons; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Receptors, Cell Surface; Time Factors | 1984 |
Effect of chronic angiotensin-converting enzyme blockade on pressor responses to exogenous angiotensin II, noradrenaline and vasopressin in deoxycorticosterone acetate salt (DOCA)-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Male; Norepinephrine; Rats; Renin; Vasopressins | 1984 |
Converting enzyme activity in regulation of blood pressure and kidney function. A review.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Kidney Function Tests; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Water-Electrolyte Balance | 1984 |
Renal prostaglandin E in the hypotensive mechanism of MK-421 in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomechanical Phenomena; Blood Pressure; Consciousness; Dipeptides; Enalapril; Hypertension; Kidney; Male; Norepinephrine; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Vasopressins | 1984 |
Plasma enalapril levels and hormonal effects after short- and long-term administration in essential hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Drug Interactions; Enalapril; Enalaprilat; Humans; Hypertension; Liver; Renin; Time Factors | 1984 |
Mechanism of the pressor response to tetradecapeptide renin substrate in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hypertension; Male; Nephrectomy; Pepstatins; Peptides; Phenylephrine; Rats; Rats, Inbred SHR; Renin | 1984 |
Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Female; Hypertension; Male; Nephrectomy; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tissue Distribution | 1984 |
Biochemical monitoring of vasoactive peptides during angiotensin converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cross Reactions; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Peptidyl-Dipeptidase A; Radioimmunoassay; Renin | 1983 |
Mechanism of action of enalapril in experimental hypertension and acute left ventricular failure.
Topics: Adrenalectomy; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Enalapril; Female; Heart Failure; Heart Ventricles; Hindlimb; Hypertension; Hypertension, Renal; Kidney; Male; Muscles; Rats; Rats, Inbred SHR; Renin; Sodium; Vasoconstriction | 1983 |
Clinical pharmacology of enalapril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biological Availability; Blood Pressure; Enalapril; Half-Life; Humans; Hypertension; Renin | 1984 |
Converting enzyme inhibitors normalize the reduced adrenal responsiveness to angiotensin II in essential hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Follow-Up Studies; Humans; Hydrocortisone; Hypertension; Potassium; Renin-Angiotensin System; Sodium | 1984 |
Beta-adrenergic regulation of circadian rhythmicity of the renin-angiotensin-aldosterone system in five subtypes of essential hypertension.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Circadian Rhythm; Female; Humans; Hypertension; Male; Renin; Sympathetic Nervous System | 1980 |
The ganglion-blocked, angiotensin II-supported rat: a model for demonstrating antihypertensive vasodilator activity.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Ganglionic Blockers; Hindlimb; Hypertension; Male; Models, Biological; Rats; Regional Blood Flow; Time Factors; Vasodilation | 1980 |
Examination of the vasopressor responsiveness potentiating plasma factor in hypertensive patients.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Cats; Furosemide; Glucose; Humans; Hypertension; Nephrectomy; Norepinephrine; Prostaglandin Antagonists; Sodium Chloride; Vasoconstriction; Water-Electrolyte Balance | 1980 |
Angiotensin II blockade during combined thiazide-beta-blocker treatment.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Drug Interactions; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Plasma Volume; Renin; Saralasin; Sodium | 1980 |
[Neurohumoral regulation problems and the pathogenesis of hypertension].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Homeostasis; Humans; Hypertension; Neurotransmitter Agents; Renin; Sympathetic Nervous System; Water-Electrolyte Balance | 1980 |
Renal effects of beta-adrenoceptor blockade.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Pindolol; Propranolol; Renin; Sodium | 1980 |
Alpha adrenergic blockade by prazosin in therapy of essential hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Prazosin; Quinazolines | 1981 |
Antihypertensive effect of the new oral angiotensin converting enzyme inhibitor "MK-421".
Topics: Administration, Oral; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dipeptides; Double-Blind Method; Drug Evaluation; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1981 |
[Pathophysiology of essential hypertension. Recent findings (author's transl)].
Topics: Angiotensin II; Animals; Brain; Electrolytes; Endorphins; Hemodynamics; Humans; Hypertension; Kidney; Neurotransmitter Agents; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Vascular Resistance | 1981 |
Neurohumoral response to hospitalization in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Epinephrine; Hospitalization; Humans; Hypertension; Middle Aged; Neurotransmitter Agents; Norepinephrine; Renin | 1981 |
Adrenoreceptor blockade in angiotensin-induced hypertension: effect on rat coronary arteries and myocardium.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Arterioles; Blood Pressure; Coronary Vessels; Heart; Hypertension; Male; Myocardium; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Vasoconstriction | 1982 |
Biochemistry and pharmacology of hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Brain; Homeostasis; Humans; Hypertension; Ion Channels; Potassium; Renin-Angiotensin System; Sodium; Sodium-Potassium-Exchanging ATPase | 1982 |
Angiotensin inhibitors for hypertension.
Topics: Administration, Oral; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Hypertension; Injections, Intravenous; Oligopeptides; Proline; Renin; Sodium; Teprotide | 1980 |
[Clinical application of peptides with inhibition of renin-angiotensin system (author's transl)].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Renin; Saralasin; Teprotide | 1980 |
Angiotensin-converting enzyme inhibitors.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Heart Failure; Humans; Hypertension; Oligopeptides; Proline; Renin; Teprotide | 1980 |
Specific inhibition of renin by an angiotensinogen analog: studies in sodium depletion and renin-dependent hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension; Macaca fascicularis; Male; Oligopeptides; Peptidyl-Dipeptidase A; Renin; Sodium; Teprotide | 1980 |
Inhibitors of angiotensin I converting enzyme for treating hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Humans; Hypertension; Renin; Teprotide | 1980 |
Altered blood pressure and renin responses to converting enzyme inhibition after aprotinin-induced kallikrein-kinin-system blockade.
Topics: Aldosterone; Angiotensin II; Aprotinin; Blood Pressure; Captopril; Humans; Hypertension; Peptidyl-Dipeptidase A; Proline; Renin | 1980 |
Blood pressure and heart rate responses to centrally administered substance P are increased in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Baclofen; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Injections, Intraventricular; Male; Pressoreceptors; Rats; Substance P | 1980 |
Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: effects on nociceptive behavior and cardiovascular regulation.
Topics: Angiotensin II; Animals; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hemodynamics; Hypertension; Male; Nociceptors; Norepinephrine; Rats; Rats, Inbred Strains; Substance P | 1981 |
Angiotensin I converting enzyme activity in portal vein studied in normotensive rats and in models of primary and secondary hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Hypertension; Male; Muscle, Smooth, Vascular; Oligopeptides; Portal Vein; Rats; Rats, Inbred Strains; Teprotide | 1981 |
The renin/angiotensin system.
Topics: Angiotensin II; Angiotensins; Blood Pressure; Captopril; Humans; Hypertension; Ischemia; Kidney; Peptidyl-Dipeptidase A; Posture; Renin; Saralasin; Teprotide | 1981 |
Verapamil-induced vasodilation is enhanced in essential hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Epinephrine; Female; Heart Rate; Humans; Hypertension; Middle Aged; Nitroprusside; Norepinephrine; Regional Blood Flow; Renin; Vasodilator Agents; Verapamil | 1982 |
[Inhibition of the renin-angiotensin system in treating arterial hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Oligopeptides; Renin-Angiotensin System; Teprotide | 1982 |
Relation of blood pressure and body sodium content during sodium depletion in normal and hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Diuretics; Humans; Hypertension; Male; Middle Aged; Renin; Sodium | 1984 |
Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Epinephrine; Forearm; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Ouabain; Regional Blood Flow; Renin; Sodium-Potassium-Exchanging ATPase; Vascular Resistance; Vasoconstriction | 1984 |
Left ventricular mass in middle-aged men. Relationship to blood pressure, sympathetic nervous activity, hormonal and metabolic factors.
Topics: Angiotensin II; Blood Glucose; Blood Pressure; Cardiomegaly; Echocardiography; Humans; Hypertension; Insulin; Isometric Contraction; Male; Middle Aged; Norepinephrine; Renin-Angiotensin System; Sympathetic Nervous System | 1983 |
[Inhibition of the renin-angiotensin system: a major breakthrough in the treatment of arterial hypertension?].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Humans; Hypertension; Kidney; Renin | 1980 |
Brain angiotensin II receptor affinity and capacity in SHR and WKY rats: effects of acute dietary changes in NaCl.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Drinking; Hypertension; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Sodium Chloride | 1980 |
In vitro steroidogenic properties of a new hypertension-producing compound isolated from normal human urine.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Cats; Cyclic AMP; Glycoproteins; Humans; Hydrocortisone; Hypertension; In Vitro Techniques; Male | 1980 |
Effect of converting enzyme inhibition on glucocorticoid hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, Sodium-Restricted; Female; Hypertension; Methylprednisolone; Peptidyl-Dipeptidase A; Rats; Renin | 1980 |
Distribution and role of angiotensin II receptor in the brain of spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Female; Hypertension; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Tissue Distribution; Tritium | 1980 |
Renin-angiotensin-aldosterone system.
Topics: Aging; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Renal Veins; Renin; Sodium | 1980 |
Comparative study of an angiotensin-II analog and a converting enzyme inhibitor.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Peptidyl-Dipeptidase A; Proline; Renin; Saralasin | 1980 |
Kinins in blood and urine with special reference to intrarenal kinin formation in normal and hypertensive individuals.
Topics: Adult; Angiotensin II; Animals; Body Water; Bradykinin; Catecholamines; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Kallikreins; Kidney; Kinins; Male; Middle Aged; Peptidyl-Dipeptidase A; Rabbits; Radioimmunoassay; Renin; Sodium; Sympathetic Nervous System | 1980 |
Endocrine profile in the long-term phase of converting-enzyme inhibition.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diet, Sodium-Restricted; Female; Humans; Hydrochlorothiazide; Hypertension; Kinins; Male; Middle Aged; Proline; Prostaglandins; Renin | 1980 |
Is the renin system necessary?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Volume; Captopril; Humans; Hypertension; Hyponatremia; Potassium; Renin; Sodium Chloride; Time Factors | 1980 |
[New viewpoints on the pathophysiology and pathogenesis of arterial hypertension].
Topics: Angiotensin II; Biological Transport; Humans; Hypertension; Kallikreins; Kinins; Norepinephrine; Potassium; Pressoreceptors; Prostaglandins; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Sodium | 1980 |
Antihypertensive effects of the novel converting-enzyme inhibitor YS 980 in spontaneously hypertensive rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Bradykinin; Catecholamines; Hypertension; Male; Rats; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1981 |
Plasma aldosterone and corticosterone responses to adrenocorticotropin, angiotensin, potassium, and stress in spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Hypertension; Male; Potassium; Potassium Chloride; Rats; Restraint, Physical; Stress, Physiological | 1981 |
Results of treatment of hypertension after renal transplantation: effects of converting enzyme inhibitor, angiotensin II analog, beta-blockade, and dopamine beta-hydroxylase inhibitor.
Topics: Adolescent; Adult; Alprenolol; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Child; Creatinine; Dopamine beta-Hydroxylase; Female; Fusaric Acid; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Renin | 1980 |
[Relation between blood pressure regulation (abnormalities) and angiotensin receptor (author's transl)].
Topics: Angiotensin II; Animals; Blood Pressure; Brain Chemistry; Homeostasis; Hypertension; Rats; Receptors, Angiotensin; Receptors, Cell Surface | 1980 |
Effects of continuous angiotensin I-converting enzyme blockade on blood pressure, sympathetic activity and renin-angiotensin system in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Disease Susceptibility; Hypertension; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Renin; Sympathetic Nervous System | 1981 |
Effect of propranolol therapy on aldosterone responses to angiotensin II and adrenocorticotropic hormone in essential hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Humans; Hypertension; Male; Middle Aged; Propranolol; Renin | 1981 |
Vasoactive peptides and hypertension: role of angiotensin converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Humans; Hypertension; Hypertension, Renovascular; Peptidyl-Dipeptidase A; Renin | 1981 |
Alterations in aldosterone biosynthesis in essential hypertensives.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Humans; Hypertension; Middle Aged; Potassium; Renin | 1981 |
Inhibition of the renin-angiotensin system. A new approach to the therapy of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Antihypertensive Agents; Captopril; Enzyme Activation; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin | 1981 |
Angiotensin-converting enzyme inhibitors: pathogenic and therapeutic implications for arterial hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Humans; Hypertension; Proline; Renal Dialysis; Renin; Sodium | 1981 |
A possible role of the brain angiotensin II receptor binding in development of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Corpus Striatum; Female; Hypertension; Hypothalamus; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Cell Surface; Thalamus | 1981 |
Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Corticosterone; Disease Models, Animal; Female; Hypertension; Potassium; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Sodium | 1982 |
Reduced number of adrenal angiotensin II receptors in the spontaneously hypertensive rat.
Topics: Adrenal Glands; Angiotensin II; Animals; Hypertension; Male; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Cell Surface; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions | 1981 |
Enhanced angiotensin-mediated facilitation of adrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cocaine; Drug Synergism; Electric Stimulation; Hypertension; Male; Norepinephrine; Rats; Receptors, Angiotensin; Saralasin; Sympathetic Nervous System; Synaptic Transmission | 1982 |
Effects of angiotensin I converting enzyme inhibitor (SQ 14,225) on the responses of blood pressure and steroid hormone to angiotensin II and ACTH infusion in hypertensive subjects.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Desoxycorticosterone; Female; Heart Rate; Humans; Hydrocortisone; Hypertension; Hypertension, Renovascular; Male; Middle Aged; Proline; Renin | 1982 |
Is angiotensin a prime factor in blood pressure control?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Humans; Hypertension; Kidney; Renin; Renin-Angiotensin System; Saralasin | 1982 |
MK 421 and prevention of genetic hypertension development in young spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Dipeptides; Enalapril; Hemodynamics; Hypertension; Male; Norepinephrine; Rats | 1982 |
Vascular smooth muscle in hypertension.
Topics: Angiotensin II; Animals; Calcium; Cations; Cats; Cell Membrane Permeability; Hypertension; Hypertrophy; In Vitro Techniques; Ion Channels; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Swine; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1982 |
A study on dehydroepiandrosterone sulfate in patients with essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Angiotensin II; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Furosemide; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Renin | 1982 |
Studies on the mechanism of the enhancement of the antihypertensive activity of captopril by a diuretic in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Drug Synergism; Heart Rate; Hydrochlorothiazide; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains; Renin; Serotonin; Vascular Resistance | 1982 |
Abnormal renin short feedback loop in essential hypertension is reversible with converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Regression Analysis; Renin; Time Factors | 1982 |
[Prevention of the development of genetic hypertension by MK 421 in the SHR].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cardiomegaly; Dipeptides; Enalapril; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains | 1982 |
Exchangeable and total body sodium and potassium in various hypertensive syndromes.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Hyponatremia; Potassium; Renin; Sodium | 1982 |
Aldosterone response to antihypertensive treatment.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Dipeptides; Enalapril; Ethanolamines; Humans; Hypertension; Middle Aged; Prazosin; Pyridazines; Renin; Renin-Angiotensin System; Vasodilator Agents; Verapamil | 1982 |
Effects of dietary sodium on brain angiotensin II receptors in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Brain; Diet, Sodium-Restricted; Hypertension; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Cell Surface; Sodium | 1982 |
Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Calcium; Heart Rate; Humans; Hydralazine; Hydrocortisone; Hypertension; Middle Aged; Nifedipine; Peptidyl-Dipeptidase A; Pyridines; Renin; Renin-Angiotensin System | 1982 |
Increased sensitivity of neurons to angiotensin II in SHR as compared to WKY rats.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Evoked Potentials; Hypertension; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Cell Surface; Septum Pellucidum | 1982 |
Specificity of the alteration in aldosterone biosynthesis in the spontaneously hypertensive rat.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Diet, Sodium-Restricted; Female; Hypertension; Natriuresis; Potassium; Rats; Rats, Inbred Strains; Species Specificity; Thyrotropin; Triiodothyronine | 1983 |
Attenuation of pressor responses to intracerebroventricular angiotensin I by angiotensin converting enzyme inhibitors and their effects on systemic blood pressure in conscious rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Brain; Captopril; Cerebral Ventricles; Dipeptides; Enalapril; Hypertension; Male; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains | 1983 |
New evidence for brain angiotensin and for its role in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain; Cells, Cultured; Dipeptides; Enalaprilat; Humans; Hypertension; Peptidyl-Dipeptidase A; Rats; Renin | 1983 |
[A method for radioimmunoassay of plasma angiotensin II using florisil].
Topics: Adult; Angiotensin II; Evaluation Studies as Topic; Female; Humans; Hypertension; Magnesium Silicates; Male; Radioimmunoassay; Silicic Acid; Silicon Dioxide | 1983 |
Converting enzyme activity and essential hypertension.
Topics: Administration, Oral; Adult; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Peptidyl-Dipeptidase A; Renin | 1983 |
[Primary reninism--study of a case due to nephroblastoma associated with severe hypertension].
Topics: Adolescent; Angiotensin II; Diagnosis, Differential; Female; Humans; Hypertension; Kidney Neoplasms; Renin; Wilms Tumor | 1983 |
10. Hypertension. A comparison of the effects of angiotensin II infusion and variations in salt intake on plasma aldosterone levels in normal subjects, patients with essential hypertension and patients with hyperaldosteronism.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Corticosterone; Desoxycorticosterone; Dexamethasone; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Infusions, Parenteral; Kinetics; Reference Values; Sodium Chloride | 1983 |
Angiotensin converting enzyme inhibition reveals an important role for the renin system in the control of normal and high blood pressure in man.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Hypertension; Male; Renin; Sodium; Time Factors; Water-Electrolyte Balance | 1983 |
Generation and elimination of angiotensins I and II in the kidney, liver and lung.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensins; Humans; Hypertension; Kidney; Liver; Lung; Middle Aged; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1983 |
Androgen modulation of adrenal angiotensin receptors.
Topics: Adrenal Cortex; Aldosterone; Androgens; Angiotensin II; Angiotensin III; Animals; Cattle; Cell Membrane; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hypertension; Receptors, Angiotensin; Receptors, Cell Surface; Testosterone | 1984 |
Pressor responses of rats to vasopressin: effect of sodium, angiotensin, and catecholamines.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Hypertension; Isoproterenol; Lypressin; Male; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Saralasin; Sodium; Species Specificity | 1983 |
Plasma vasopressin in rats: effect of sodium, angiotensin, and catecholamines.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Captopril; Hypertension; Isoproterenol; Male; Norepinephrine; Radioimmunoassay; Rats; Rats, Inbred Strains; Sodium; Species Specificity | 1983 |
Verapamil-induced vasodilator response is enhanced in essential hypertension.
Topics: Adult; Angiotensin II; Calcium; Epinephrine; Female; Forearm; Humans; Hypertension; Middle Aged; Nitroprusside; Norepinephrine; Regional Blood Flow; Renin; Vasodilation; Verapamil | 1983 |
Mechanism of suppressed renin-angiotensin system in spontaneously hypertensive rat (SHR).
Topics: Angiotensin II; Animals; Body Weight; Catecholamines; Diet; Fusaric Acid; Hypertension; Kidney; Male; Potassium; Prostaglandins E; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sodium | 1983 |
Circulatory effects of renin-angiotensin system antagonists during halothane anaesthesia in hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Enflurane; Halothane; Heart Rate; Hypertension; Indomethacin; Male; Proline; Rats; Renin-Angiotensin System; Saralasin; Shock, Hemorrhagic | 1983 |
A case of functioning parathyroid carcinoma with hypereninemic hypertension.
Topics: Angiotensin II; Female; Humans; Hypercalcemia; Hyperparathyroidism; Hypertension; Middle Aged; Parathyroid Neoplasms; Renin | 1983 |
Diurnal rhythms of blood pressure, plasma renin activity, angiotensin II and catecholamines in normotensive and hypertensive pregnancies.
Topics: Adolescent; Adult; Angiotensin II; Birth Weight; Blood Pressure; Circadian Rhythm; Epinephrine; Female; Humans; Hypertension; Norepinephrine; Parity; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1983 |
[Role of a competitive antagonist of angiotensin II (saralasin) in the diagnosis and therapy of arterial hypertension].
Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Renin; Saralasin; Sodium | 1983 |
Ketamine hypertension and the renin-angiotensin system.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Ketamine; Renin; Renin-Angiotensin System; Thiopental | 1983 |
[Studies on the pathogenesis of arterial hypertension in acromegaly. I. The renin-angiotensin-aldosterone system].
Topics: Acromegaly; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Growth Hormone; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1983 |
Correction of altered noradrenaline reactivity in essential hypertension by indapamide.
Topics: Adolescent; Adult; Aged; Angiotensin II; Diuretics; Dose-Response Relationship, Drug; Epinephrine; Female; Hemodynamics; Humans; Hypertension; Indapamide; Male; Middle Aged; Norepinephrine; Posture; Potassium; Renin; Sodium | 1983 |
[The pressor and adrenal responses to angiotensin II in patients with normoreninemic essential hypertension--the influence of sodium intake and captopril].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Proline; Renin | 1983 |
Effect of captopril on the renin-angiotensin system in hypertensive children.
Topics: Adolescent; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Child; Humans; Hypertension; Proline; Renin; Renin-Angiotensin System | 1983 |
Defect in the sodium-modulated tissue responsiveness to angiotensin II in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Humans; Hypertension; Kinetics; Middle Aged; p-Aminohippuric Acid; Renin; Sodium | 1983 |
Captopril enhances vascular and adrenal responsiveness to angiotensin II in essential hypertension.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Metabolic Clearance Rate; Middle Aged; Norepinephrine; p-Aminohippuric Acid; Proline; Renal Circulation | 1984 |
A comparison of biological effects of three angiotensin II antagonists in sodium depleted hypertensive patients.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Saralasin | 1983 |
Renin, renin substrate, angiotensin II, and vasopressin in plasma during treatment with captopril in hypertension and heart failure.
Topics: Adult; Aged; Angiotensin II; Angiotensinogen; Angiotensins; Blood Pressure; Captopril; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Proline; Renin; Time Factors; Vasopressins | 1983 |
Role of renin-angiotensin system in cardiopulmonary bypass hypertension.
Topics: Angiotensin II; Cardiopulmonary Bypass; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Saralasin; Vascular Resistance | 1984 |
The effect of in vitro captopril and angiotensin II on plasma renin activity.
Topics: Angiotensin II; Captopril; Enzyme Activation; Humans; Hypertension; Proline; Renin; Trypsin | 1984 |
Effects of verapamil in hypertensive patients.
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hypertension; Middle Aged; Plasma Volume; Renal Circulation; Renin; Vascular Resistance; Verapamil | 1984 |
Effect of angiotensin III on blood pressure, renin-angiotensin-aldosterone system in normal and hypertensive subjects.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Female; Humans; Hydrocortisone; Hypertension; Infusions, Parenteral; Kidney; Male; Middle Aged; Renin; Renin-Angiotensin System | 1984 |
[Features of vascular reactivity, sodium metabolism and its humoral regulation in healthy subjects with a family history of hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sodium Chloride; Stress, Psychological; Taste Threshold | 1984 |
Mechanisms of central prostaglandin E2 hypertension in conscious dogs, sheep, and calves.
Topics: Anesthesia; Angiotensin II; Animals; Captopril; Carotid Arteries; Cattle; Chemoreceptor Cells; Dinoprostone; Dogs; Hemodynamics; Hypertension; Injections, Intra-Arterial; Male; Phentolamine; Pressoreceptors; Propranolol; Prostaglandins E; Receptors, Adrenergic; Renin; Sheep | 1984 |
Altered pressor responses in long-term nitrendipine treatment.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Calcium; Creatinine; Double-Blind Method; Heart Rate; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Nifedipine; Nitrendipine; Norepinephrine; Potassium; Random Allocation; Renin; Sodium | 1984 |
[Comparison of effects of two angiotensin II antagonists on blood pressure, heart rate, plasma renin activity, and plasma aldosterone concentration in the same hypertensive patients].
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Heart Rate; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Middle Aged; Renin; Saralasin | 1984 |
Captopril in hypertension after renal transplantation.
Topics: Adult; Angiotensin II; Captopril; Drug Resistance; Female; Humans; Hypertension; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Proline; Proteinuria; Renin; Time Factors | 1984 |
Renin secretion in advanced diabetic nephropathy.
Topics: Adult; Angiotensin II; Captopril; Chlorides; Diabetic Nephropathies; Dihydralazine; Humans; Hypertension; Middle Aged; Renin | 1984 |
Clinical syndromes associated with disorders of renal tubular chloride transport: excess and deficiency of a circulating factor?
Topics: Aldosterone; Angiotensin II; Bartter Syndrome; Body Weight; Chlorides; Female; Furosemide; Humans; Hyperaldosteronism; Hypertension; Kidney Tubules; Male; Middle Aged; Potassium; Renin; Renin-Angiotensin System | 1984 |
Renin, angiotensin II, aldosterone, catecholamines, prostaglandins and vasopressin. The importance of pressor and depressor factors for hypertension in pregnancy.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Catecholamines; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins; Renin | 1984 |
A very sensitive direct radioimmunoassay system for plasma angiotensin II and its clinical application in various hypertensive diseases.
Topics: Angiotensin II; Captopril; Glomerulonephritis; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay; Renin | 1984 |
Plasma prostaglandins during the intravenous infusion of angiotensin II in pregnant women.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Angiotensin II; Dinoprost; Dinoprostone; Epoprostenol; Female; Humans; Hypertension; Infusions, Parenteral; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Prostaglandins; Prostaglandins E; Prostaglandins F | 1984 |
Changes in active and inactive renin and in angiotensin II across the kidney in essential hypertension and renal artery stenosis.
Topics: Adult; Angiotensin II; Aorta; Bethanidine; Enzyme Activation; Evaluation Studies as Topic; Female; Humans; Hypertension; Kidney; Male; Methods; Renal Artery Obstruction; Renal Veins; Renin; Trypsin; Vena Cava, Inferior | 1984 |
[Is there a relation between the renin-angiotensin-aldosterone system and vasopressin secretion in essential hypertension?].
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Posture; Renin; Renin-Angiotensin System; Water-Electrolyte Balance | 1984 |
Calf muscle haemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with a familial predisposition to hypertension: changes during increased salt intake.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Hemodynamics; Humans; Hypertension; Leg; Male; Muscles; Regional Blood Flow; Renin; Renin-Angiotensin System; Sodium Chloride; Vascular Resistance | 1984 |
Effects of development and captopril treatment on central angiotensin II--sensitive neurons.
Topics: Angiotensin II; Animals; Captopril; Hypertension; Male; Neurosecretory Systems; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1984 |
Is the renin-angiotensin system involved in urinary concentration mechanisms?
Topics: Angiotensin II; Animals; Dogs; Furosemide; Humans; Hypertension; Kidney Concentrating Ability; Kinetics; Male; Osmolar Concentration; Propranolol; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Saralasin; Sodium; Urine | 1984 |
Failure of angiotensin II to reduce plasma renin activity in hypertensive pregnant women.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Drug Evaluation; Female; Humans; Hypertension; Male; Menstrual Cycle; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Renin | 1984 |
Renal secretion of inactive renin and extraction of angiotensin II in renal artery stenosis in man: factors determining renal vein renin ratio.
Topics: Angiotensin II; Aorta; Female; Humans; Hypertension; Kidney; Male; Renal Artery Obstruction; Renal Circulation; Renal Veins; Renin; Secretory Rate | 1984 |
Factors related to first dose hypotensive effect of captopril: prediction and treatment.
Topics: Aged; Angiotensin II; Captopril; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Hypotension; Male; Middle Aged; Proline; Renin; Sodium | 1983 |
Effects of chronic arachidonate on blood pressure of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Body Weight; Catecholamines; Hypertension; Indomethacin; Male; Norepinephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Time Factors; Vascular Resistance | 1983 |
Plasma concentrations, renal excretion, and tissue release of prostaglandins in the rat with dexamethasone-induced hypertension.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Body Weight; Dexamethasone; Hypertension; Kidney; Kinetics; Male; Potassium; Prostaglandins; Rats; Rats, Inbred Strains; Sodium | 1984 |
Clinical manifestations and diagnosis of pregnancy-induced hypertension.
Topics: Angiotensin II; Antigens; Antithrombin III; Bed Rest; Diastole; Endothelium; Factor VIII; Female; Humans; Hypertension; Kidney; Kidney Function Tests; Liver Function Tests; Posture; Pre-Eclampsia; Pregnancy; Proteinuria; Uric Acid; Vasodilation; von Willebrand Factor | 1984 |
Hypertension induced changes in cerebral capillary permeability to water are mediated by afferent neuronal connections from the carotid sinus to the brain.
Topics: Afferent Pathways; Angiotensin II; Animals; Body Water; Brain; Capillary Permeability; Carotid Sinus; Cerebrovascular Circulation; Female; Hypertension; Male; Metaraminol; Neurons; Rats; Rats, Inbred Strains; Vagotomy | 1984 |
Leukotriene D4 inhibits cardiovascular responses to sympathetic stimulation, angiotensin and vasopressin in the pithed spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Decerebrate State; Electric Stimulation; Heart Rate; Hematocrit; Hypertension; Nitroprusside; Norepinephrine; Rats; Rats, Inbred SHR; Spinal Cord; SRS-A; Sympathetic Nervous System; Vasopressins | 1984 |
Effect of angiotensin II on vasopressin in plasma and platelets in SH and WKY rats.
Topics: Angiotensin II; Animals; Blood Platelets; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasopressins | 1984 |
[Tumor vascularity under hypertension induced by intravenous infusion of angiotensin II. An angiographic observation].
Topics: Angiography; Angiotensin II; Humans; Hypertension; Infusions, Parenteral; Liver Neoplasms; Neoplasms; Rectal Neoplasms | 1984 |
Cardiovascular and adrenal sensitivity to angiotensin II in essential hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Sodium | 1984 |
Effect of K+ depletion on renal and systemic hemodynamics.
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Humans; Hypertension; Potassium Deficiency; Prostaglandins; Rats; Renal Circulation; Vascular Resistance | 1984 |
[Effects of continuous pure tone stimulation on blood pressure, plasma norepinephrine and urinary norepinephrine concentration in stroke-prone spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Body Weight; Female; Heart Rate; Hypertension; Male; Noise; Norepinephrine; Rats; Rats, Inbred SHR | 1984 |
The renal kallikrein-kinin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Bumetanide; Erythrocyte Indices; Hypertension; Kallikreins; Kinins; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium | 1984 |
Angiotensin II-induced hypertension in the rat. Effects on the plasma concentration, renal excretion, and tissue release of prostaglandins.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Body Weight; Dinoprostone; Hypertension; Kidney; Kidney Concentrating Ability; Male; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Systole; Vena Cava, Inferior | 1983 |
Effects of subpressor doses of angiotensin II on renal haemodynamics at different blood-pressure levels.
Topics: Angiotensin II; Blood Pressure; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Renal Circulation; Renal Veins; Vascular Resistance | 1983 |
Relation of rates of excretion of urinary prostaglandin E metabolites to administration of angiotensin, aldosterone, and spironolactone in vivo.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensin II; Animals; Hypertension; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Spironolactone | 1984 |
[Study of angiotensin II].
Topics: Angiotensin II; Humans; Hypertension; Radioimmunoassay; Renin-Angiotensin System | 1983 |
Cardiovascular responsiveness to physiological agonists of male rats made hypertensive by long-term exposure to cadmium.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Cadmium; Catechol O-Methyltransferase Inhibitors; Copper; Epinephrine; Heart; Heart Rate; Hemodynamics; Histamine; Hypertension; Kidney; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Zinc | 1984 |
Formation of a vasopressor substance in the incubated serum of patients with various hypertensive diseases.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Biological Assay; Blood Pressure; Humans; Hypertension; Kinetics; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Vasoconstrictor Agents | 1984 |
Reversibility of blood-brain barrier dysfunction in acute hypertension induced by angiotensin.
Topics: Acute Disease; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Evans Blue; Hypertension; Male; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Effect of induced hypertension on experimentally-induced cerebral arterial spasm.
Topics: Angiotensin II; Animals; Basilar Artery; Blood Pressure; Calcium Gluconate; Cats; Disease Models, Animal; Hypertension; Ischemic Attack, Transient; Norepinephrine | 1984 |
Relationship between plasma aldosterone and angiotensin II before and after noradrenergic inhibition in normal subjects and patients with mild essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Debrisoquin; Female; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Norepinephrine | 1984 |
Effects of acute, angiotensin-induced hypertension on intrarenal arteries in the rat.
Topics: Acute Disease; Angiotensin II; Animals; Arteries; Arterioles; Blood Pressure; Hypertension; Intestines; Kidney; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Permeability; Rats; Rats, Inbred Strains; Renal Circulation; Vasoconstriction | 1984 |
Angiotensin II in neuronal cultures from brains of normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Hypertension; Neurons; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Catecholamines, angiotensin II and sodium concentrations in cerebrospinal fluid in young men with borderline hypertension.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Catecholamines; Dopamine; Epinephrine; Heart Rate; Humans; Hypertension; Male; Norepinephrine; Sodium | 1984 |
Cerebral blood flow changes with diuretic therapy in elderly subjects with systolic hypertension.
Topics: Aged; Angiotensin II; Blood Pressure; Cerebrovascular Circulation; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Renin; Systole; Uric Acid | 1982 |
Endogenous brain angiotensin II-mediated sympathetic nerve responses are not augmented in mature spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain Chemistry; Captopril; Estrogens; Female; Heart Rate; Hypertension; Injections, Intraventricular; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sympathetic Nervous System | 1982 |
The renin-angiotensin system, prostaglandins and pregnancy-induced hypertension--physiology or pathology?
Topics: Angiotensin II; Dinoprostone; Epoprostenol; Female; Homeostasis; Humans; Hypertension; Ischemia; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins; Prostaglandins E; Renin-Angiotensin System | 1982 |
[A study on the relationship between renin-angiotensin-aldosterone system and essential hypertension].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System; Sodium | 1982 |
Characterization of a group of essential hypertensives with impaired regulation of aldosterone.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Potassium; Renin; Sodium; Spironolactone | 1982 |
The renin-angiotensin system and hypertension.
Topics: Adrenal Glands; Angiotensin II; Blood Vessels; Blood Volume; Humans; Hypertension; Renin; Renin-Angiotensin System; Sodium | 1982 |
The renin system for understanding human hypertension: evidence for blood pressure control by a bipolar vasoconstriction-volume mechanism. Prorenin as a determinant of renin secretion.
Topics: Adult; Angiotensin II; Cold Temperature; Enzyme Precursors; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Kidney; Male; Middle Aged; Norepinephrine; Renin; Renin-Angiotensin System; Sodium; Vasoconstriction | 1982 |
Biological significance of active and inactive renin in hypertensive patients.
Topics: Adult; Angiotensin II; Blood Pressure; Captopril; Cold Temperature; Enzyme Activation; Enzyme Precursors; Female; Humans; Hypertension; Male; Renin; Saralasin | 1982 |
Cultured juxtaglomerular cells cause hypertension by secreting angiotensin.
Topics: Angiotensin II; Angiotensin III; Animals; Captopril; Cells, Cultured; Hypertension; Juxtaglomerular Apparatus; Nephrectomy; Rats; Saralasin | 1982 |
[Catecholamines in the blood and the renin-angiotensin-aldosterone axis in essential hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Catecholamines; Electrolytes; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1981 |
Systemic arterial hypertension associated with cardiac surgery.
Topics: Angiotensin II; Antihypertensive Agents; Aortic Coarctation; Aortic Valve; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Diazoxide; Heart Valve Prosthesis; Humans; Hypertension; Intraoperative Complications; Intubation, Intratracheal; Nitroglycerin; Postoperative Period; Renin; Sternum; Time Factors | 1980 |
Leucocyte cation transport in essential hypertension: its relation to the renin-angiotensin system.
Topics: Aldosterone; Angiotensin II; Biological Transport; Diet, Sodium-Restricted; Humans; Hypertension; Leukocytes; Renin; Sodium | 1981 |
[Captopril - profile of a new antihypertensive (author's transl)].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertension, Renovascular; Proline; Rats; Rats, Inbred Strains; Renin | 1981 |
The effect of captopril on catecholamines, renin activity, angiotensin II and aldosterone in plasma during physical exercise in hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Proline; Renin; Renin-Angiotensin System | 1981 |
Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Electrolytes; Humans; Hypertension; Long-Term Care; Proline; Renin; Renin-Angiotensin System | 1982 |
[Functional and structural behavior of the cardiovascular system of normotonic and spontaneously hypertensive rats following chemical sympathectomy and angiotensin administration].
Topics: Angiotensin II; Animals; Blood Circulation; Coronary Circulation; Hydroxydopamines; Hypertension; Male; Myocardium; Oxidopamine; Rats; Rats, Inbred Strains; Sympathectomy, Chemical | 1981 |
[Treatment of the hypertensive crisis by blocking the renin-angiotensin system (author's transl)].
Topics: Adult; Angiotensin II; Captopril; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin-Angiotensin System; Saralasin | 1982 |
[Vascular reactivity in young genetically hypertensive rats of the Lyons strain].
Topics: Angiotensin II; Animals; Blood Pressure; Cocaine; Hypertension; Male; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1982 |
Pressor responsiveness to angiotensin II in hospitalized primigravid women with pregnancy-induced hypertension.
Topics: Angiotensin II; Blood Pressure; Female; Hospitalization; Humans; Hypertension; Parity; Pregnancy; Pregnancy Complications, Cardiovascular | 1983 |
[Effect of the sympathetic nervous system on changes in the resistance of the hemato-encephalic barrier in arterial hypertension].
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Capillary Permeability; Cats; Female; Hypertension; Male; Norepinephrine; Sympathectomy; Sympathetic Nervous System; Vascular Resistance | 1983 |
Pressor responsiveness to vasopressin and angiotensin II in spontaneously hypertensive rats: effects of dietary sodium.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Diet; Dose-Response Relationship, Drug; Hypertension; Male; Phenoxybenzamine; Rats; Rats, Inbred Strains; Sodium | 1983 |
Decrease of angiotensin sensitivity after bed rest and strongly sodium-restricted diet in pregnancy.
Topics: Adult; Angiotensin II; Bed Rest; Diet, Sodium-Restricted; Female; Humans; Hypertension; Parity; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Sodium | 1983 |
Increased systemic vascular responsiveness to catecholamines in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Regional Blood Flow; Tyramine; Vascular Resistance | 1983 |
[State of resistive blood vessels of the rat kidney during development of hereditary (spontaneous) hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney; Male; Organ Culture Techniques; Perfusion; Rats; Renal Artery; Vascular Resistance | 1983 |
[Mineralocorticoid-induced changes of vascular reactivity to noradrenaline and angiotensin II in baboons].
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Female; Hypertension; Male; Mineralocorticoids; Norepinephrine; Papio | 1983 |
Angiotensin synthesis in the brain and increased turnover in hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Brain; Hypertension; Nephrectomy; Radioimmunoassay; Rats | 1983 |
[Saralasin in the diagnosis of angiotensin-dependent hypertension and in the study of the renin-angiotensin-aldosterone system].
Topics: Angiotensin II; Humans; Hypertension; Receptors, Angiotensin; Renin-Angiotensin System; Saralasin | 1983 |
[Functional and structural vascular reactions following intermittent administration of angiotensin in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Hyperplasia; Hypertension; Hypertrophy; Male; Rats; Rats, Inbred Strains | 1983 |
Reactivity of isolated digital arteries in hypertension.
Topics: Angiotensin II; Barium; Barium Compounds; Chlorides; Cyproheptadine; Female; Hand; Humans; Hypertension; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Potassium Chloride; Serotonin; Serotonin Antagonists; Vascular Resistance; Verapamil | 1981 |
Angiotensin II, prostaglandin E2 and ventromedial hypothalamus in the genesis of hypertensive states.
Topics: Angiotensin II; Animals; Dinoprostone; Drug Interactions; Female; Hypertension; Male; Prostaglandins E; Rabbits; Ventromedial Hypothalamic Nucleus | 1982 |
Renal function, sodium excretion and the renin-angiotensin-aldosterone system in relation to blood pressure. An epidemiological and physiological study.
Topics: Angiotensin II; Blood Pressure; Cross-Sectional Studies; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Middle Aged; Renin-Angiotensin System; Sodium; Sweden | 1982 |
Constrasts and similarities of acute hemodynamic responses to specific antagonism of angiotensin II ([Sar1, Thr8] A II) and to inhibition of converting enzyme (captopril).
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Blood Volume; Captopril; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Proline; Renin | 1980 |
Vasodepressor property of the converting enzyme inhibitor captopril (SQ 14 225): the role of factors other than renin-angiotensin blockade in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Disease Models, Animal; Female; Hypertension; Nephrectomy; Proline; Rats; Renin; Saralasin | 1980 |
The diagnostic and therapeutic uses of saralasin in renal transplant hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Graft Rejection; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Renin; Saralasin; Transplantation, Homologous | 1980 |
Acute effects of saralasin on plasma aldosterone in different pathophysiological conditions.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Bartter Syndrome; Child; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hydrocortisone; Hypertension; Liver Cirrhosis; Male; Middle Aged; Renin; Saralasin | 1980 |
[Hemodynamics and the renin-angiotensin-aldosterone system in primary hypertension].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Renin | 1980 |
Angiotensin II, plasma renin and sodium depletion as determinants of blood pressure response to saralasin in essential hypertension.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hypertension; Hyponatremia; Infusions, Parenteral; Male; Metolazone; Middle Aged; Renin; Saralasin; Sodium; Spironolactone | 1980 |
Hypertension associated with hyperparathyroidism is not responsive to angiotensin blockade.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Calcium; Creatinine; Female; Humans; Hyperparathyroidism; Hypertension; Male; Middle Aged; Parathyroid Hormone; Posture; Renin; Saralasin | 1980 |
Saralasin infusion in renovascular and essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Middle Aged; Renin; Saralasin; Sodium | 1980 |
Renin-angiotensin system and blood volume in patients with dialysis-resistant hypertension.
Topics: Angiotensin II; Blood Pressure; Blood Volume; Humans; Hypertension; Renal Dialysis; Renin; Saralasin | 1980 |
[Pathogenesis of arterial hypertension].
Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Middle Aged; Osmotic Pressure; Renin | 1980 |
Biological significance of active and inactive renin in man.
Topics: Adult; Angiotensin I; Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Renin; Saralasin | 1980 |
Effects of standard oral glucose loading on the renin-angiotensin-aldosterone system and its relationship to circulating insulin.
Topics: Adult; Angiotensin II; Diuretics; Female; Glucose; Humans; Hypertension; Insulin; Male; Middle Aged; Posture; Potassium; Renin | 1980 |
Hypertension in the elderly.
Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Vessels; Blood Volume; Brain; Heart; Humans; Hypertension; Middle Aged; Renin; Risk; Sympathetic Nervous System | 1980 |
Abnormal adrenal and vascular responses to angiotensin II and an angiotensin antagonist in acromegaly.
Topics: Acromegaly; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Middle Aged; Posture; Potassium; Reference Values; Renin; Saralasin; Sodium | 1980 |
A comparative study on (des-aspartyl1)-angiotensin II and angiotensin II in patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Humans; Hypertension; Middle Aged; Receptors, Angiotensin; Renin | 1980 |
Effect of propranolol on the urinary excretion of prostaglandin E and plasma renin activity in hypertensive patients.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Potassium; Propranolol; Prostaglandins E; Renin; Sodium | 1980 |
Effect of neonatal sympathectomy with 6-hydroxydopamine on reactivity of the renin-angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Body Weight; Female; Hydralazine; Hydroxydopamines; Hypertension; Male; Norepinephrine; Rats; Renin; Sympathectomy; Sympathetic Nervous System | 1980 |
[Renin-angiotensin-aldosterone system in diabetes, arterial hypertension and orthostatic hypotension].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diabetes Mellitus; Female; Humans; Hypertension; Hypotension, Orthostatic; Male; Middle Aged; Pulse; Renin; Urine | 1980 |
Different patterns in essential hypertension and possible choice of antihypertensive drugs.
Topics: Adult; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Cardiac Output; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Renin; Vascular Resistance | 1980 |
Hypertensive mechanisms in coarctation of the aorta. Further studies of the renin-angiotensin system.
Topics: Adolescent; Angiotensin II; Aortic Coarctation; Child; Child, Preschool; Furosemide; Humans; Hypertension; Renin; Saralasin | 1980 |
Hypertension screening and treatment with angiotensin inhibitors. Saralasin and captopril.
Topics: Angiotensin II; Angiotensins; Blood Pressure; Captopril; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Proline; Renin; Saralasin | 1980 |
Captopril in clinical hypertension. Changes in components of renin-angiotensin system and in body composition in relation to fall in blood pressure with a note on measurement of angiotensin II during converting enzyme inhibition.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diuretics; Humans; Hypertension; Potassium; Proline; Renal Artery Obstruction; Renin; Sodium | 1980 |
[Effect of saralasin on blood pressure, plasma renin and plasma noradrenaline in hypertensive patients].
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hypertension; Norepinephrine; Renin; Saralasin | 1980 |
[Essential arterial hypertension. Effects of labetalol on blood pressure and renin-angiotensin system (author's transl)].
Topics: Adult; Angiotensin II; Blood Pressure; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Renin | 1980 |
Dietary modification of the vascular effect of prostacyclin in hypertensive rats.
Topics: Acetylglucosaminidase; Angiotensin II; Animals; Aorta; Blood Pressure; Cathepsin D; Cathepsins; Diet; Epoprostenol; Hypertension; Linolenic Acids; Prostaglandins; Rats | 1980 |
Rate of angiotensin II generation within the human pulmonary vascular bed.
Topics: Angiotensin II; Female; Humans; Hypertension; Kidney Diseases; Male; Pulmonary Circulation; Renin | 1980 |
[Saralasin in subjects with low renin arterial hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Saralasin; Sodium | 1980 |
Angiotensin II and not sodium status is the major determinant of the agonistic/antagonistic balance of saralasin's actions.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin; Sodium | 1980 |
Hypotensive effects of captopril, saralasin and bromocriptine in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Bromocriptine; Captopril; Dopamine; Hypertension; In Vitro Techniques; Oxytocin; Pituitary Gland, Posterior; Proline; Rats; Saralasin; Swine; Vasopressins | 1980 |
Captopril and hypertension development in the SHR.
Topics: Angiotensin II; Animals; Atenolol; Blood Pressure; Captopril; Dihydralazine; Hypertension; Male; Proline; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Vascular Resistance | 1980 |
Antihypertensive effects of angiotensin blockade: saralasin versus captopril.
Topics: Adult; Angiotensin II; Blood Pressure; Captopril; Humans; Hypertension; Male; Middle Aged; Proline; Renin; Saralasin | 1980 |
[Factors contributing to the etiology of hypertension in pregnancy. 2. Renin-angiotensin system and toxemia of pregnancy].
Topics: Angiotensin II; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1980 |
[Modifications of vascular reactivity. 2. Modifications of reactivity].
Topics: Angiotensin II; Arteries; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1980 |
Suppression of captopril-induced increase in plasma renin activity by des-Asp1-,Ileu8-angiotensin II in man.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Blood Pressure; Captopril; Female; Humans; Hypertension; Isoleucine; Kinetics; Male; Middle Aged; Proline; Renin | 1981 |
Evidence for prejunctional inhibition of norepinephrine release by captopril in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Heart Rate; Hypertension; Norepinephrine; Proline; Rats; Sympathetic Nervous System | 1980 |
[Studies on effects of renin-angiotensin system on hemodynamics and cardiovascular system in essential hypertension (author's transl)].
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aged; Angiotensin II; Cardiography, Impedance; Cardiovascular System; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Renin; Systole | 1980 |
[Urinary prostaglandin E in patients with hypertension--relationship to renin-angiotensin-aldosterone system (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Male; Prostaglandins E; Radioimmunoassay; Renin | 1980 |
PGI2-specific antibodies administered in vivo suggest against a role for endogenous PGI2 as a circulating vasodepressor hormone in the normotensive and spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Antibodies; Blood Pressure; Epoprostenol; Hypertension; Norepinephrine; Prostaglandins; Prostaglandins E; Rats | 1980 |
[Renin-angiotensin-aldosterone system in essential hypertension. Inappropriately high plasma aldosterone in young patients with severe hypertension and in older hypertensives].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin; Sex Factors | 1980 |
Independence of renin production and hypertension in abdominal aortic aneurysmectomy.
Topics: Aged; Angiotensin II; Aorta, Abdominal; Aortic Aneurysm; Blood Pressure; Constriction; Female; Hemodynamics; Humans; Hypertension; Intraoperative Period; Male; Middle Aged; Postoperative Complications; Postoperative Period; Renin | 1981 |
Combined captopril and spironolactone treatment in Conn's syndrome with renal impairment and refractory hypertension.
Topics: Adult; Angiotensin II; Captopril; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypertension; Kidney Failure, Chronic; Male; Proline; Sodium; Spironolactone | 1981 |
Acute tolerance to prazosin in conscious hypertensive rats: involvement of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Captopril; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Hydrochlorothiazide; Hypertension; Indomethacin; Male; Methyltyrosines; Prazosin; Propranolol; Quinazolines; Rats; Renin | 1981 |
[Functional state of the renin-angiotensin system in the diuretic therapy of hypertension].
Topics: Adult; Angiotensin II; Blood Pressure; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Natriuresis; Renin; Time Factors | 1981 |
[Symptomatic arterial hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Diagnosis, Differential; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney; Regional Blood Flow; Renin | 1981 |
Renin.
Topics: Angiotensin I; Angiotensin II; Humans; Hypertension; Kidney; Renin; Saralasin | 1981 |
New developments in our knowledge of blood pressure regulation.
Topics: Angiotensin II; Animals; Blood Pressure; Hormones; Humans; Hypertension; Neurons; Pressoreceptors; Reflex; Renin; Vasopressins | 1981 |
Conn's syndrome in a patient with acromegaly.
Topics: Acromegaly; Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Middle Aged; Pituitary Neoplasms; Renin; Syndrome | 1981 |
Plasma aldosterone response to angiotensin II in sodium-restricted elderly subjects with essential hypertension.
Topics: Aged; Aging; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertension; Infusions, Intra-Arterial; Male; Middle Aged; Renin | 1981 |
[Effects of saralasin on 20 hypertensive patients (author's transl)].
Topics: Adolescent; Adult; Aged; Angiotensin II; Blood Pressure; Chemical Phenomena; Chemistry; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Renin; Saralasin | 1980 |
Captopril in primary hypertension. Effects related to the renin-angiotensin-aldosterone and kallikrein-kinin systems.
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Female; Humans; Hypertension; Kallikreins; Kinins; Male; Middle Aged; Posture; Proline; Renin | 1981 |
Hemodynamic effects of [Sar1, Ile8] AII, an angiotensin II analog, in the renin subgroups of essential hypertension.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Angiotensin II; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Renin | 1981 |
Angiotensin II and sodium as determinants of the agonistic--antagonistic balance of saralasin's actions.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin; Sodium | 1981 |
Acute effects of captopril on blood pressure and circulating hormone levels in salt-replete and depleted normal subjects and essential hypertensive patients.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Proline; Pulse; Renin; Sodium | 1981 |
Effects of angiotensin II analog on blood pressure, renin and aldosterone in women on oral contraceptives and toxemia.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Estrogens; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1981 |
A new bioassay method for measurement of angiotensin II using isolated bovine adrenal cells: clinical application on the plasma renin activity.
Topics: Adrenal Glands; Angiotensin II; Animals; Biological Assay; Cattle; Humans; Hypertension; In Vitro Techniques; Radioimmunoassay; Renin | 1980 |
[Hypertension: pathogenetic factors, evaluation and risk factors].
Topics: Aged; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Renin; Risk | 1981 |
Role of the brain iso-renin--angiotensin system in experimental hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Endopeptidases; Hypertension; Hypertension, Renovascular; Male; Rats; Renin; Saralasin | 1981 |
[Changes in the renin-angiotensin-aldosterone system during graduated ergometric tests in patients with essential arterial hypertension and in normal controls].
Topics: Adrenergic Fibers; Adult; Aldosterone; Angiotensin II; Exercise Test; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Male; Middle Aged; Renin | 1981 |
[Captopril in the treatment of hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Captopril; Humans; Hypertension; Proline; Renin | 1981 |
Captopril withdrawal after chronic therapy.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Epinephrine; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Norepinephrine; Posture; Proline; Renin | 1981 |
Sodium intake and renal responses to captopril in normal man and in essential hypertension.
Topics: Adolescent; Adult; Angiotensin II; Bradykinin; Captopril; Diet, Sodium-Restricted; Humans; Hypertension; Kidney; Middle Aged; Proline; Renal Circulation; Renin; Sodium | 1981 |
Blood pressure and the renin--angiotensin--aldosterone system.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1981 |
Effect of angiotensin II and converting enzyme inhibitor (captopril) on blood pressure, plasma renin activity and aldosterone in primary aldosteronism.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Captopril; Humans; Hyperaldosteronism; Hypertension; Proline; Renin | 1981 |
The effect of oral prazosin on blood pressure and plasma concentrations of renin and angiotensin II in man.
Topics: Administration, Oral; Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Prazosin; Quinazolines; Renin | 1981 |
The response to the angiotensin antagonist saralasin in predicting therapeutic outcome in hypertension treated with frusemide.
Topics: Aged; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Follow-Up Studies; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin; Retrospective Studies; Saralasin | 1981 |
Evidence against an interaction of angiotensin II with the sympathetic nervous system in man.
Topics: Adult; Aged; Angiotensin II; Captopril; Epinephrine; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sympathetic Nervous System | 1981 |
Rise in plasma concentration of aldosterone during long-term angiotensin II suppression.
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Depression, Chemical; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin; Time Factors | 1981 |
Absence of an antihypertensive effect of 12 hour infusions of an angiotensin antagonist in chronic renal hypertensive rabbits.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Blood Urea Nitrogen; Disease Models, Animal; Hypertension; Hypertension, Renal; Male; Rabbits; Renin; Renin-Angiotensin System; Sodium Chloride | 1981 |
Comparison of the immediate hemodynamic effects of SQ 14225 (Captopril) and [Sar1, Ileu8] angiotensin II in patients with dialysis resistant hypertension.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Angiotensin II; Blood Pressure; Captopril; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Proline; Renal Dialysis; Renin-Angiotensin System | 1982 |
[Interrelationship between plasma renin activity and angiotensin II level --A preliminary analysis of 773 samples from normotensives and essential hypertensives (author's transl)].
Topics: Adult; Aged; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin; Sodium | 1981 |
Antihypertensive effects of captopril and saralasin in essential and renal hypertension.
Topics: Angiotensin II; Captopril; Electrolytes; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Proline; Renin; Renin-Angiotensin System; Saralasin | 1982 |
Racial difference in salivary sodium-potassium ratio in low renin essential hypertension.
Topics: Adult; Aged; Aging; Angiotensin II; Black People; Humans; Hypertension; Middle Aged; Potassium; Racial Groups; Renin; Saliva; Sodium; White People | 1982 |
The role of brain angiotensin II in the mechanism of the pressor responses to intracisternal injection of hypertonic NaCl in urethane anesthetized rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Anesthesia; Angiotensin II; Animals; Blood Pressure; Brain Chemistry; Captopril; Cisterna Magna; Hypertension; Injections; Male; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic; Sodium Chloride; Urethane | 1982 |
Effect of angiotensin converting enzyme inhibitor on serum aldosterone and potassium level.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Captopril; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Proline; Renin-Angiotensin System | 1982 |
Exchangeable sodium and saralasin-blocking, plasma renin and aldosterone in pre- and postoperative young patients with aortic coarctation.
Topics: Adolescent; Aldosterone; Angiotensin II; Aortic Coarctation; Child; Humans; Hypertension; Natriuresis; Postoperative Period; Renin; Renin-Angiotensin System; Saralasin | 1982 |
Discrimination of renovascular from essential hypertension by converting enzyme inhibition with an orally active compound.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Middle Aged; Proline; Renin | 1982 |
Captopril treatment: inter-dose variations in renin, angiotensins I and II, aldosterone and blood pressure.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin; Renin-Angiotensin System; Time Factors | 1982 |
Preoperative and postoperative renin levels in coarctation of the aorta.
Topics: Adolescent; Angiotensin II; Aortic Coarctation; Child; Child, Preschool; Diet, Sodium-Restricted; Diuretics; Humans; Hypertension; Renin | 1982 |
Aldosterone responsiveness to angiotensin II after sodium restriction in subjects with low renin essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Sodium | 1982 |
Relation of arterial pressure with body sodium, body potassium and plasma potassium in essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Blood Pressure; Body Surface Area; Body Weight; Humans; Hypertension; Middle Aged; Potassium; Renin; Sodium; Urea | 1982 |
Use of saralasin as a diagnostic test in hypertension. Report of a Consensus Committee.
Topics: Angiotensin II; Humans; Hypertension; Hypertension, Renovascular; Renin; Saralasin | 1982 |
Human placental leucine aminopeptidase (P-LAP) as a hypotensive agent.
Topics: Angiotensin II; Animals; Female; Humans; Hypertension; Leucyl Aminopeptidase; Male; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Renin | 1982 |
Exaggerated salt appetite of spontaneously hypertensive rats is decreased by central angiotensin-converting enzyme blockade.
Topics: Angiotensin II; Animals; Appetite; Brain; Captopril; Hydralazine; Hypertension; Injections, Intraventricular; Male; Proline; Rats; Rats, Inbred Strains; Sodium Chloride; Thirst | 1982 |
Blood pressure in relation to the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Analysis of Variance; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1982 |
Vincristine reduces damage of the blood-brain barrier induced by high intravascular pressure.
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Brain Diseases; Disease Models, Animal; Hypertension; Male; Rats; Rats, Inbred Strains; Vincristine | 1980 |
Increased specific binding of angiotensin II in the organum vasculosum of the laminae terminalis area of the spontaneously hypertensive rat brain.
Topics: Angiotensin II; Animals; Binding Sites; Cerebral Cortex; Hypertension; Rats; Rats, Inbred Strains; Species Specificity; Subfornical Organ; Telencephalon | 1980 |
Effect of acute vasopressin infusion on blood pressure and plasma angiotensin II in normotensive and DOCA-salt hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Hypertension; Male; Rats; Rats, Inbred Strains; Vasopressins | 1982 |
The value of the angiotensin sensitivity test in the early diagnosis of hypertensive disorders in pregnancy.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; False Negative Reactions; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Probability | 1982 |
Lead, hypertension, and the renin-angiotensin system in rats.
Topics: Aging; Angiotensin II; Animals; Creatinine; Female; Hypertension; Lead; Organ Size; Potassium; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Renin-Angiotensin System; Sodium | 1982 |
[Hormonal contraception and hypertension].
Topics: Angiotensin II; Angiotensinogen; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Estrogens; Female; Humans; Hypertension; Liver; Renin-Angiotensin System; Sodium; Vasoconstriction | 1982 |
Actions of angiotensin II on the isolated spontaneously hypertensive rat kidney.
Topics: Angiotensin II; Animals; Glomerular Filtration Rate; Hypertension; Kidney; Male; Rats; Renal Circulation; Sodium; Vascular Resistance | 1982 |
Parallel adrenal and renal abnormalities in young patients with essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Diuresis; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Natriuresis | 1982 |
[Comparative evaluation of the effect of bradykinin and angiotensin II on hemodynamics in normotensive rats, spontaneously hypertensive rats and rats with renovascular hypertension].
Topics: Angiotensin II; Animals; Bradykinin; Hemodynamics; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Rats | 1982 |
Nocturnal food-related hyperdipsia in the adult spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Drinking Behavior; Feeding Behavior; Histamine; Hypertension; Intracellular Fluid; Light; Male; Osmolar Concentration; Rats; Water-Electrolyte Balance | 1982 |
The renin-angiotensin system in pregnancy: why bother?
Topics: Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Renin-Angiotensin System | 1982 |
Bed rest in pregnancy.
Topics: Angiotensin II; Bed Rest; Female; Fetal Death; Humans; Hypertension; Placenta Previa; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria | 1982 |
Effect of indomethacin on responses to [sar-ileu]-angiotensin II.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Blood Pressure; Drug Interactions; Humans; Hypertension; Indomethacin; Muscle, Smooth, Vascular; Prostaglandins; Time Factors | 1982 |
Central mechanisms in DOC-salt hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Desoxycorticosterone; Hypertension; Injections, Intraventricular; Male; Norepinephrine; Rats; Rats, Inbred Strains; Sodium Chloride; Sympathetic Nervous System; Vascular Resistance; Water-Electrolyte Balance | 1982 |
Impaired angiotensin-induced drinking in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Binding Sites; Brain; Drinking; Female; Hypertension; Injections, Intraventricular; Kinetics; Male; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Sex Factors; Species Specificity | 1982 |
Infusion of bovine parathyroid hormone1-34 attenuates the pressor response to angiotensin II in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Parathyroid Hormone; Peptide Fragments; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Teriparatide | 1982 |
Use of continuous saralasin infusion to control hypertension.
Topics: Angiotensin II; Child; Female; Humans; Hypertension; Infant; Infusions, Parenteral; Male; Saralasin; Ultrafiltration | 1982 |
Studies on the interactions of acetyl glycerol ether phosphoryl choline with the sympathetic nervous system in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Heart Rate; Hemodynamics; Hypertension; Male; Phenylephrine; Platelet Activating Factor; Rats; Rats, Inbred Strains; Spinal Cord; Sympatholytics | 1982 |
[The arterial endothelium--present state of knowledge].
Topics: Acetates; Angiotensin II; Animals; Arteries; Arteriosclerosis; Carbon Monoxide; Cyanides; Endothelium; Epinephrine; Humans; Hypertension; Lipoproteins; Molecular Weight; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits | 1982 |
Aortic input impedance in normal man and arterial hypertension: its modification during changes in aortic pressure.
Topics: Adult; Angiotensin II; Aorta; Blood Pressure; Electric Conductivity; Humans; Hypertension; Male; Middle Aged; Nitroprusside | 1982 |
Cardiovascular reactivity of genetically hypertensive rats of the Lyon strain.
Topics: Angiotensin II; Animals; Blood Pressure; Cocaine; Hypertension; Male; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains | 1982 |
[Approaches to the enhancement of anticancer activity in cancer chemotherapy].
Topics: Angiotensin II; Antineoplastic Agents; Drug Therapy, Combination; Humans; Hypertension; Neoplasms; Phenobarbital | 1982 |
A technique to investigate surface morphology and endothelial cell replication of small arteries: a study in acute angiotensin-induced hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Autoradiography; Endothelium; Hypertension; Male; Rats; Rats, Inbred Strains; Surface Properties | 1982 |
Baroreceptor reflexes after coarctectomy.
Topics: Adolescent; Adult; Angiotensin II; Aortic Coarctation; Blood Pressure; Child; Electrocardiography; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Postoperative Period; Pressoreceptors | 1981 |
[[Participation of angiotensin II in the mechanism of arterial hypertension in coarctation of the aorta].
Topics: Adolescent; Adult; Angiotensin II; Aortic Coarctation; Cardiac Catheterization; Child; Humans; Hypertension; Middle Aged; Saralasin | 1980 |
Vascular responses of the perfused intestine to vasoactive agents during the development of two-kidney, one-clip Goldblatt hypertension in dogs.
Topics: Angiotensin II; Animals; Cardiac Output; Dogs; Female; Hemodynamics; Hypertension; Intestine, Small; Male; Norepinephrine; Perfusion; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Serotonin; Time Factors; Vascular Resistance | 1981 |
Saralasin testing in pediatric hypertension.
Topics: Angiotensin II; Child; Humans; Hypertension; Hypertension, Renovascular; Saralasin | 1981 |
Cerebrovascular sympathetic denervation and blood-brain barrier function in conscious rats.
Topics: Angiotensin II; Animals; Bicuculline; Blood-Brain Barrier; Cerebrovascular Circulation; Electric Stimulation; Hypertension; Male; Rats; Sympathectomy; Sympathetic Nervous System | 1980 |
Carotid artery constriction in acute hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Aorta; Blood-Brain Barrier; Carotid Arteries; Cerebrovascular Circulation; Constriction; Hypertension; Male; Permeability; Rats | 1981 |
Systemic arterial compliance and diastolic runoff in essential hypertension.
Topics: Adult; Angiotensin II; Arteries; Brachial Artery; Diastole; Elasticity; Hemodynamics; Humans; Hypertension; Male; Nitroprusside | 1981 |
Cerebral neuronal activity in spontaneously hypertensive rats as demonstrated by the 14C-deoxyglucose method.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Deoxy Sugars; Deoxyglucose; Glucose; Heart Rate; Hypertension; Male; Neurons; Rats | 1981 |
[Functional and structural reactivity of the arterial vascular system to angiotensin II in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Heart Rate; Hypertension; Kidney; Lung; Male; Myocardium; Rats | 1981 |
Vasopressin secretion in the New Zealand genetically hypertensive rat.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Hematocrit; Hypertension; Male; Potassium; Rats; Rats, Inbred Strains; Reference Values; Sodium; Species Specificity; Vasopressins | 1981 |
Induction of chronic arterial hypertension in rats by repeated transient hypertensive rises in blood pressure. Possible pathogenetic role of delayed hypersensitivity against arteries and arterioles.
Topics: Angiotensin II; Animals; Arteries; Capillary Permeability; Female; Hypersensitivity, Delayed; Hypertension; Kidney; Male; Rats | 1981 |
Correction of altered noradrenaline reactivity in essential hypertension by indapamide.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Blood Volume; Diuretics; Female; Heart Rate; Humans; Hypertension; Indapamide; Male; Middle Aged; Norepinephrine; Potassium; Sodium | 1981 |
The importance of vasopressin in the mechanism maintaining hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Desoxycorticosterone; Hypertension; Male; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Sodium; Vasopressins | 1981 |
Exaggerated pressor responsiveness to norepinephrine in nonazotemic diabetes mellitus.
Topics: Adult; Angiotensin II; Blood Pressure; Diabetes Mellitus; Diabetic Angiopathies; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Pressoreceptors | 1981 |
[Clinical analysis of the renin-angiotnesin system status of essental hypertension (author's transl)].
Topics: Adult; Age Factors; Aged; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System | 1980 |
[Interrelationship between the brain and kidney renin--angiotensin systems in combined hypertension: the effect of a central block with saralasin].
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Hypertension; Injections, Intraventricular; Kidney; Male; Nerve Block; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Saralasin | 1981 |
[Cerebral vascular reactivity of cats with chronic hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Cats; Cerebral Arteries; Chronic Disease; Hemodynamics; Hypertension; Norepinephrine; Vascular Resistance; Veins | 1981 |
The effects of angiotensin on respiratory patterns of anaesthetized dogs.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Denervation; Dilatation; Dogs; Female; Hypertension; Male; Phenylephrine; Pressoreceptors; Respiration; Tidal Volume; Vagotomy | 1981 |
Depression of heart function after angiotensin II infusion in patients on chronic hemodialysis.
Topics: Adult; Angiotensin II; Blood Pressure; Chronic Disease; Female; Glomerulonephritis; Heart; Humans; Hypertension; Male; Middle Aged; Nephrotic Syndrome; Renal Dialysis; Tuberculosis, Renal | 1981 |
Hemodynamics of a new angiotensin antagonist, [Sar1, Thr8]A II, in hypertensive man.
Topics: Angiotensin II; Blood Pressure; Blood Volume; Cardiac Output; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Renin; Vascular Resistance | 1980 |
Angiotensin in the brain?
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Humans; Hypertension; Kidney; Rats; Receptors, Angiotensin; Renin; Stress, Physiological | 1980 |
Effect of indomethacin in two siblings with a renin-dependent hypertension, hyperaldosteronism and hypokalemia.
Topics: Adolescent; Adult; Angiotensin II; Drug Therapy, Combination; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Indomethacin; Male; Propranolol; Prostaglandins; Renin; Saralasin; Spironolactone; Syndrome | 1980 |
Rebound hypertensive after sodium nitroprusside prevented by saralasin in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Carbon Dioxide; Ferricyanides; Halothane; Hydrogen-Ion Concentration; Hypertension; Male; Nitroprusside; Oxygen; Rats; Renin; Saralasin; Time Factors | 1980 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Diuretics; Female; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Potassium; Potassium Chloride; Pyrazines; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1980 |
Angiotensin and hypertension.
Topics: Angiotensin II; Humans; Hypertension | 1980 |
Changes in renal vascular reactivity at various stages of deoxycorticosterone hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Hypertension; Kidney; Male; Nephrectomy; Norepinephrine; Rats; Vascular Resistance; Vasopressins | 1980 |
[Infusion of angiotensin II and the changes of posture of the arterial pressure as a means of predicting pregnancy toxemia].
Topics: Acute Disease; Angiotensin II; Female; Humans; Hypertension; Injections, Intravenous; Posture; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Prognosis | 1980 |
Vasoconstriction and increased blood pressure in the development of accelerated vascular disease.
Topics: Anesthesia; Angiotensin II; Animals; Blood Vessels; Constriction, Pathologic; Hypertension; Male; Muscle, Smooth; Necrosis; Rats | 1980 |
Prostaglandins A and E levels in human essential hypertension.
Topics: Adult; Angiotensin II; Animals; Arteries; Biological Assay; Blood Pressure; Epinephrine; Humans; Hypertension; Indomethacin; Middle Aged; Norepinephrine; Prostaglandins A; Prostaglandins E; Rabbits | 1980 |
Alterations in renal vascular resistance and reactivity in spontaneous hypertension of rats.
Topics: Aging; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Norepinephrine; Rats; Serotonin; Vascular Resistance; Vasopressins | 1980 |
Plasma angiotensin II: dipsogenic levels and angiotensin-generating capacity of renin.
Topics: Anesthesia; Angiotensin II; Animals; Diabetes Insipidus; Dose-Response Relationship, Drug; Drinking Behavior; Hypertension; Infusions, Parenteral; Radioimmunoassay; Rats; Thirst | 1980 |
Pathomorphological reactions of myocardium and intramural vessels of rats in the course of hypertension induced by depot angiotensin. Autoradiographic, light and electron microscopic investigations.
Topics: Angiotensin II; Animals; Coronary Vessels; DNA; Endothelium; Hypertension; Male; Mitosis; Myocardium; Necrosis; Rats; Sulfates | 1980 |
The concept of autoregulation of total blood flow and its role in hypertension.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Blood Volume; Cardiac Output; Desoxycorticosterone; Dogs; Extracellular Space; Homeostasis; Humans; Hypertension; Hypertension, Renovascular; Kidney; Norepinephrine; Vascular Resistance; Vasodilation | 1980 |
The role of the renal effects of angiotensin II in hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Hypertension; Kidney; Sodium | 1980 |
The actions of angiotensin II in the chicken.
Topics: Angiotensin II; Animals; Blood Pressure; Chickens; Columbidae; Heart Rate; Hypertension; Turkeys | 1980 |
Blood pressure response to an angiotensin II antagonist in thyrotoxic patients with and without high blood pressure.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adolescent; Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hyperthyroidism; Male; Middle Aged | 1980 |
Role of angiotensin II in oral contraceptive hypertension in anesthetized rats.
Topics: Anesthesia; Angiotensin II; Animals; Body Weight; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Diet; Drug Combinations; Female; Hypertension; Mestranol; Norethynodrel; Rats | 1980 |
Vascular reactivity to angiotensin and noradrenaline in rats maintained on a sodium free diet or made hypertensive with desoxycorticosterone acetate and salt (DOCA/salt).
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Desoxycorticosterone; Diet, Sodium-Restricted; Hormones; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Rats; Sodium Chloride; Systole; Vasoconstriction; Vasoconstrictor Agents | 1980 |
Vascular reactivity to angiotensin and noradrenaline in spontaneously and renal hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Female; Hormones; Hypertension; Hypertension, Renal; Male; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Rats; Stimulation, Chemical | 1980 |
[Role of mineralocorticoid regulation of vascular reactivity in the arterial pressure reaction to increased salt uptake in healthy persons].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Vessels; Dose-Response Relationship, Drug; Health; Humans; Hypertension; Middle Aged; Mineralocorticoids; Norepinephrine; Sodium Chloride | 1980 |
Increased 18-hydroxycorticosterone responses to frusemide in essential hypertension.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Corticosterone; Female; Furosemide; Humans; Hydrocortisone; Hypertension; Male; Middle Aged | 1980 |
The sustained antihypertensive effect of chronic cerebroventricular infusion of angiotensin antagonist in spontaneously hypertensive rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Hypertension; Infusions, Parenteral; Kinetics; Male; Rats | 1980 |
Experimental angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Heart; Hypertension; Potassium; Sodium; Sodium Chloride; Time Factors | 1980 |
Renal vascular resistance and reactivity in the neurogenic hypertensive rat.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Hemodynamics; Hypertension; Kidney; Male; Norepinephrine; Pressoreceptors; Rats; Vascular Resistance | 1980 |
Age-rated profile of cardiovascular reactivity to norepinephrine and angiotensin II in normal and hypertensive man.
Topics: Adult; Aging; Angiotensin II; Female; Hemodynamics; Humans; Hypertension; Male; Norepinephrine | 1980 |
[Searching for a long acting angiotensin II antagonist].
Topics: Affinity Labels; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Humans; Hypertension; Hypotension; Injections, Intravenous; Rabbits; Receptors, Angiotensin | 1980 |
Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Enalapril; Hypertension; Isoquinolines; Lung; Male; Rabbits; Rats; Rats, Inbred SHR; Tetrahydroisoquinolines; Time Factors | 1995 |
Does the rapidity with which hypertension reverses on unclipping a clipped kidney and on stopping long-term infusion of angiotensin II make unlikely an important role for vascular hypertrophy in maintaining the hypertension seen before reversal?
Topics: Angiotensin II; Animals; Blood Vessels; Constriction; Humans; Hypertension; Hypertension, Renovascular; Hypertrophy; Time Factors | 1995 |
Relation between renin and prorenin in plasma from hypertensive patients and normal people: evidence for different renin:prorenin ratios.
Topics: Angiotensin II; Enzyme Precursors; Factor XII Deficiency; Humans; Hypertension; Hypertension, Renal; Hypoaldosteronism; Kallikreins; Prekallikrein; Reference Values; Renal Artery Obstruction; Renin | 1995 |
Effects of the angiotensin II receptor antagonist losartan on 24-hour blood pressure profiles of primary and secondary hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Enalapril; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tetrazoles | 1995 |
Effects of diadenosine polyphosphates, ATP and angiotensin II on membrane voltage and membrane conductances of rat mesangial cells.
Topics: Adenosine; Adenosine Triphosphate; Angiotensin II; Animals; Cell Line; Dinucleoside Phosphates; Glomerular Mesangium; Hypertension; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1995 |
Effects of diadenosine polyphosphates, ATP and angiotensin II on cytosolic Ca2+ activity and contraction of rat mesangial cells.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcium; Cell Line; Cytosol; Dinucleoside Phosphates; Fura-2; Glomerular Mesangium; Hypertension; Muscle Contraction; Patch-Clamp Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1995 |
Effects of an endothelin receptor antagonist in rats with cyclosporine-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Azepines; Base Sequence; Blood Pressure; Cyclosporins; Data Interpretation, Statistical; DNA Probes; Endothelin Receptor Antagonists; Hypertension; Indoles; Injections, Subcutaneous; Male; Mesenteric Arteries; Molecular Sequence Data; Norepinephrine; Polymerase Chain Reaction; Rats; Rats, Inbred WKY; Receptors, Endothelin; RNA, Messenger; Vasoconstriction | 1995 |
Cloning, characterization, and genetic mapping of the rat type 2 angiotensin II receptor gene.
Topics: Alleles; Angiotensin II; Animals; Base Sequence; Chromosome Mapping; Cloning, Molecular; Genes; Genetic Markers; Genomic Library; Hypertension; In Situ Hybridization, Fluorescence; Molecular Sequence Data; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Angiotensin; Transcription, Genetic; X Chromosome | 1995 |
Effects of losartan on blood pressure, metabolic alterations, and vascular reactivity in the fructose-induced hypertensive rat.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Pressure; Endothelins; Fructose; Hypertension; Imidazoles; In Vitro Techniques; Insulin; Insulin Resistance; Losartan; Male; Mesenteric Artery, Superior; Rats; Rats, Sprague-Dawley; Tetrazoles; Triglycerides; Vasoconstriction | 1995 |
Pressor and reflex sensitivity is altered in spontaneously hypertensive rats treated with angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Infusions, Intravenous; Injections, Intravenous; Male; Peptide Fragments; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex; Time Factors; Vasoconstrictor Agents | 1995 |
Regulation of neuronal calcitonin gene-related peptide expression. Role of increased blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Hypertension; Male; Neurons; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin; RNA; RNA Probes; RNA, Messenger; Up-Regulation; Vasoconstrictor Agents | 1995 |
Comparable effects of angiotensin II and converting enzyme blockade on hemodynamics and cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Cardiac Output; Cardiomegaly; Heart; Hemodynamics; Hypertension; Kidney; Lisinopril; Male; Organ Size; Rats; Rats, Inbred SHR; Rats, Wistar; Renal Circulation; Tetrazoles | 1995 |
Mesenteric small artery changes after vasoconstrictor infusion in young rats.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelium, Vascular; Hemodynamics; Hypertension; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Vascular Resistance; Vasoconstrictor Agents | 1993 |
Pharmacology of SC-52458, an orally active, nonpeptide angiotensin AT1 receptor antagonist.
Topics: Administration, Oral; Adrenal Cortex; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Blood Pressure; Female; Heart Rate; Hypertension; In Vitro Techniques; Male; Muscle, Smooth; Peptidyl-Dipeptidase A; Pyridines; Rabbits; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin; Tetrazoles; Uterus | 1993 |
[Sodium intake and angiotensin in hypertension induced by chronic NO synthase inhibition in the rat].
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Arginine; Diet, Sodium-Restricted; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sodium, Dietary | 1993 |
Nitric oxide-dependent and -independent mechanisms of vasodilation in pregnancy.
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Arginine; Electric Stimulation; Female; Hypertension; In Vitro Techniques; Mesenteric Artery, Superior; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 1993 |
Dietary calcium supplementation prevents the development of hypertension in deoxycorticosterone-salt-treated dogs.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Volume; Calcium; Calcium, Dietary; Desoxycorticosterone; Dogs; Hemodynamics; Hypertension; Male; Norepinephrine; Vascular Resistance | 1994 |
Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Disease Models, Animal; Endothelins; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vascular Resistance | 1994 |
Effects of ramipril on contractile oscillations in arteries from genetically hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Age Factors; Angiotensin II; Animals; Aorta; Blood Pressure; Carotid Arteries; Hypertension; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oscillometry; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1994 |
Antagonism between the vascular renin-angiotensin and natriuretic peptide systems in vascular remodelling.
Topics: Angiotensin II; Animals; Arteriosclerosis; Atrial Natriuretic Factor; Base Sequence; Cattle; Cell Division; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation; Guanylate Cyclase; Hypertension; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Proteins; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Atrial Natriuretic Factor; Renin-Angiotensin System; RNA; Stimulation, Chemical | 1994 |
[Role of endothelial nitric oxide synthases in the contractile response to angiotensin II of the aorta in rats. Wistar Kyoto and hypertensive rats].
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Aorta; Endothelium, Vascular; Hypertension; Male; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1994 |
Transient decrease in high blood pressure by in vivo transfer of antisense oligodeoxynucleotides against rat angiotensinogen.
Topics: Analysis of Variance; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cells, Cultured; DNA, Complementary; Genetic Therapy; Hypertension; Liver; Male; Oligonucleotides, Antisense; Parainfluenza Virus 1, Human; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Wistar; RNA; Time Factors; Transfection | 1995 |
Antihypertensive effects of angiotensin fragments in SHR.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Molecular Sequence Data; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Structure-Activity Relationship | 1995 |
Differences in electrophysiological properties of angiotensinergic pathways from the subfornical organ to the median preoptic nucleus between normotensive Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Electric Stimulation; Electrophysiology; Hypertension; Iontophoresis; Male; Neural Pathways; Neurons; Preoptic Area; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Subfornical Organ | 1995 |
Hypertensive intra-arterial chemotherapy for endometrial carcinoma assessed by transvaginal Doppler ultrasound and magnetic resonance imaging.
Topics: Adenocarcinoma; Adult; Aged; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Blood Flow Velocity; Blood Pressure; Endometrial Neoplasms; Female; Humans; Hypertension; Infusions, Intra-Arterial; Magnetic Resonance Imaging; Middle Aged; Regional Blood Flow; Ultrasonography, Doppler | 1995 |
Derivatives of 5-[[1-(4'-carboxybenzyl)imidazolyl]methylidene]hydantoins as orally active angiotensin II receptor antagonists.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Haplorhini; Hydantoins; Hypertension; In Vitro Techniques; Male; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Structure-Activity Relationship; Vasoconstriction | 1995 |
Effects of U-97018 on pressor responses to intracerebroventricularly administered angiotensin II in conscious normotensive rats.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Injections, Intravenous; Injections, Intraventricular; Losartan; Male; Pyridazines; Pyridines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Saralasin; Tetrazoles | 1995 |
Lead alters growth and reduces angiotensin II receptor density of rat aortic smooth muscle cells.
Topics: Actins; Angiotensin II; Animals; Aorta; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Environmental Pollution; Fluorescent Antibody Technique; Humans; Hypertension; Kinetics; Lead; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Receptors, Angiotensin; Receptors, Atrial Natriuretic Factor; Reference Values; Risk Factors | 1995 |
In vivo pharmacology of L-159,913, a new highly potent and selective nonpeptide angiotensin II receptor antagonist.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dogs; Female; Hypertension; Imidazoles; Kidney; Losartan; Macaca mulatta; Male; Natriuresis; Pan troglodytes; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Tetrazoles; Triazoles | 1995 |
Prevention by blockade of angiotensin subtype1-receptors of the development of genetic hypertension but not its heritability.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Body Weight; Disease Models, Animal; Diuresis; Female; Genetic Diseases, Inborn; Heart; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Nicotinic Acids; Organ Size; Phenotype; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Tetrazoles | 1995 |
Angiotensin II receptor antagonist CV-11974 and cerebral blood flow autoregulation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cerebrovascular Circulation; Homeostasis; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 1995 |
Effect of losartan on haematology and haemorheology in elderly patients with essential hypertension: a pilot study.
Topics: Aged; Angiotensin II; Biphenyl Compounds; Blood Circulation; Blood Viscosity; Female; Hematocrit; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Pilot Projects; Tetrazoles | 1995 |
Influence of angiotensin II type 1 receptor polymorphism on aortic stiffness in never-treated hypertensive patients.
Topics: Adult; Aged; Analysis of Variance; Angiotensin II; Aorta; Blood Flow Velocity; Blood Pressure; Cholesterol, HDL; Data Interpretation, Statistical; Diastole; Female; Genotype; Heterozygote; Homozygote; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Pulse; Receptors, Angiotensin; Renin-Angiotensin System; Systole | 1995 |
Endopeptidase inhibition in angiotensin-induced hypertension. Effect of SCH 39370 in sheep.
Topics: Analysis of Variance; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Dipeptides; Female; Hemodynamics; Hypertension; Metalloendopeptidases; Neprilysin; Protease Inhibitors; Renin-Angiotensin System; Sheep; Time Factors | 1995 |
Control of carotid vasomotor tone by local renin-angiotensin system in normotensive and spontaneously hypertensive rats. Role of endothelium and flow.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Carotid Arteries; Endothelium, Vascular; Hypertension; Imidazoles; In Vitro Techniques; Lisinopril; Losartan; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Tetrazoles; Transducers; Vasomotor System | 1995 |
Enhanced responses to L-arginine in aortic rings from rats with angiotensin-dependent hypertension.
Topics: Angiotensin II; Animals; Aorta; Aortic Coarctation; Arginine; Blood Pressure; Hypertension; In Vitro Techniques; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley | 1995 |
Direct effects of angiotensin I, angiotensin II, an ACE inhibitor and a serine proteinase inhibitor on cultured heart cells from spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Hypertension; Immunohistochemistry; Myocardium; Rats; Rats, Inbred SHR; Serine Proteinase Inhibitors; Uridine | 1995 |
Transforming growth factor beta 1 modulates angiotensin II-induced calcium influx in vascular smooth muscle.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcium; Cells, Cultured; Cytosol; Hypertension; Male; Muscle, Smooth, Vascular; Naphthalenes; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1995 |
Antihypertensive actions of angiotensin-(1-7) in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Heart Rate; Hypertension; Infusions, Intravenous; Male; Natriuresis; Peptide Fragments; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Time Factors; Vasopressins | 1995 |
[Clinical experience with angiotensin II antagonists in arterial hypertension].
Topics: Angiotensin II; Antihypertensive Agents; Humans; Hypertension | 1994 |
Antihypertensive therapy targeted to the needs of the patient: focus on the renin-angiotensin system; older and newer agents.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Imidazoles; Losartan; Quality of Life; Renin-Angiotensin System; Tetrazoles | 1995 |
Evolving concepts in the management of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Humans; Hypertension | 1995 |
Angiotensin receptors: physiology and pharmacology.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles | 1995 |
Altered angiotensinogen amino acid sequence and plasma angiotensin II levels in genetically hypertensive rats. A study on cause and effect.
Topics: Alleles; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Base Sequence; Female; Genetic Linkage; Hypertension; Male; Molecular Sequence Data; Point Mutation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium, Dietary | 1995 |
Cardiovascular effects after the intracerebroventricular administration of peptide and nonpeptide angiotensin antagonists in Dahl salt-sensitive rats.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Brain; Heart Rate; Hypertension; Imidazoles; Injections, Intraventricular; Losartan; Male; Rats; Renin-Angiotensin System; Tetrazoles | 1995 |
[The disturbance of Ca2+ transport and the changes of some relative factors in arterial smooth muscle cells from spontaneously hypertensive rats with different age].
Topics: Age Factors; Angiotensin II; Animals; Aorta; Biological Transport, Active; Calcium; Calmodulin; Cells, Cultured; Cyclic AMP; Hypertension; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1995 |
Acute myocardial and vascular responses to specific angiotensin II antagonism in the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Electrocardiography; Heart; Hemodynamics; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Vasoconstriction | 1995 |
Losartan in patients with renal insufficiency.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Diabetic Nephropathies; Humans; Hypertension; Hypertension, Renal; Imidazoles; Kidney Failure, Chronic; Losartan; Tetrazoles | 1995 |
The angiotensin II receptor antagonist losartan: a new advance in the treatment of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Costs; Humans; Hypertension; Imidazoles; Losartan; Tetrazoles | 1995 |
Induction of cardiac angiotensin I-converting enzyme with dietary NaCl-loading in genetically hypertensive and normotensive rats.
Topics: Angiotensin II; Animals; Enzyme Induction; Heart Ventricles; Hemodynamics; Hypertension; Male; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Sodium Chloride, Dietary | 1995 |
Angiotensin and asymmetric fetal growth.
Topics: Adult; Angiotensin II; Angiotensinogen; Animals; Birth Weight; Cardiovascular Diseases; Cephalometry; Eclampsia; Embryonic and Fetal Development; Female; Humans; Hypertension; Infant, Newborn; Pregnancy; Pregnancy Complications, Cardiovascular | 1995 |
[Medical angiotensin II-receptor blockade in hypertension and heart failure].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Agents; Heart Failure; Humans; Hypertension; Imidazoles; Losartan; Renin; Tetrazoles | 1995 |
GABA and bicuculline-induced blood pressure changes in spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Bicuculline; Blood Pressure; Drug Interactions; gamma-Aminobutyric Acid; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley | 1993 |
Actions of norepinephrine and angiotensin II on aortic rings of adult and aged normotensive and hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Aorta; Hypertension; In Vitro Techniques; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tachyphylaxis; Vasoconstriction | 1993 |
Angiotensin blockade reverses hypertension during long-term nitric oxide synthase inhibition.
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Arginine; Diuresis; Dose-Response Relationship, Drug; Hypertension; Male; Nicotinic Acids; Nitric Oxide Synthase; Nitroarginine; Proteinuria; Pyridines; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Time Factors | 1993 |
Endothelin modulates dihydropyridine receptor decreased binding in hippocampal slices from normotensive and spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Endothelins; Hippocampus; Hypertension; In Vitro Techniques; Isradipine; Male; Membranes; Muscle Proteins; Nicardipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 1993 |
Acute hemodynamic and neurohumoral profile of dilevalol in hypertensive patients with ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II; Cardiac Catheterization; Dopamine; Epinephrine; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Middle Aged; Myocardial Ischemia; Myocardium; Neurotransmitter Agents; Norepinephrine; Oxygen Consumption; Renin | 1993 |
Glucocorticoids but not mineralocorticoids modulate endothelin-1 and angiotensin II binding in SHR vascular smooth muscle cells.
Topics: Aldosterone; Androstanols; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Endothelin Receptor Antagonists; Endothelins; Glucocorticoids; Hypertension; Imidazoles; Losartan; Male; Mifepristone; Muscle, Smooth, Vascular; Peptides, Cyclic; Rats; Rats, Inbred SHR; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Tetrazoles; Viper Venoms | 1995 |
Effects of kidney transplantation on the renin-angiotensin systems of the recipients.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Hybridization, Genetic; Hypertension; Kidney; Kidney Transplantation; Male; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 1994 |
Defective G protein activation of the cAMP pathway in rat kidney during genetic hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cholera Toxin; Cyclic AMP; Fenoldopam; GTP-Binding Proteins; Hematocrit; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Signal Transduction; Sodium Fluoride; Species Specificity; Time Factors; Vascular Resistance; Vasoconstriction | 1995 |
Delivery of angiotensin II type 1 receptor antisense inhibits angiotensin action in neurons from hypertensive rat brain.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Base Sequence; Brain; Carrier Proteins; Cells, Cultured; DNA Primers; Gene Expression; Genetic Vectors; Hypertension; Molecular Sequence Data; Neurons; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Oligonucleotides, Antisense; Polymerase Chain Reaction; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Recombinant Proteins; Retroviridae; RNA, Messenger; Symporters; Transfection | 1995 |
Captopril normalises systolic blood pressure in rats with hypertension induced by fetal exposure to maternal low protein diets.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Captopril; Diet, Protein-Restricted; Disease Models, Animal; Female; Hypertension; Lung; Peptidyl-Dipeptidase A; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Renin; Renin-Angiotensin System | 1995 |
Angiotensin II type I receptor antagonist inhibits the gene expression of transforming growth factor-beta 1 and extracellular matrix in cardiac and vascular tissues of hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Enalapril; Extracellular Matrix Proteins; Gene Expression Regulation; Hypertension; Male; Mesenteric Arteries; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 1995 |
Renal nerves, renin, and angiotensinogen gene expression in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Autoradiography; Blood Pressure; Gene Expression; Hypertension; Kidney; Kidney Function Tests; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Renal Circulation; Renin; RNA, Messenger; Species Specificity; Sympathetic Nervous System | 1995 |
Angiotensin II and sympathetic activity in sodium-restricted essential hypertension.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Diet, Sodium-Restricted; Female; Forearm; Humans; Hypertension; Isoproterenol; Male; Middle Aged; Norepinephrine; Plethysmography; Propranolol; Saralasin; Sympathetic Nervous System; Vasoconstriction | 1995 |
Pharmacological properties of KT3-671, a novel nonpeptide angiotensin II receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Binding, Competitive; Blood Pressure; Bradykinin; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hypertension; Imidazoles; In Vitro Techniques; Liver; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Artery; Tetrazoles | 1995 |
Regulation of blood pressure by the type 1A angiotensin II receptor gene.
Topics: Angiotensin II; Animals; Blood Pressure; Electroporation; Female; Gene Targeting; Heterozygote; Homozygote; Hypertension; Kidney; Male; Mice; Mice, Knockout; Perfusion; Receptors, Angiotensin; Systole | 1995 |
Effect of angiotensin II on calcium release phenomena in normal and hypertrophied single cardiac myocytes.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Cardiomegaly; Electric Stimulation; Heart Ventricles; Hypertension; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Reference Values | 1994 |
Regional haemodynamic effects of human and rat adrenomedullin in conscious rats.
Topics: Adrenomedullin; Angiotensin II; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Calcitonin Gene-Related Peptide; Catheterization, Peripheral; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Hypertension; Hypotension; Laser-Doppler Flowmetry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Peptides; Random Allocation; Rats; Regional Blood Flow; Renal Circulation; Tachycardia; Vasopressins | 1995 |
Angiotensin and bradykinin peptides in the TGR(mRen-2)27 rat.
Topics: Aldosterone; Amino Acid Sequence; Angiotensin II; Animals; Animals, Genetically Modified; Bradykinin; Female; Hypertension; Kidney; Male; Molecular Sequence Data; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin | 1995 |
Hypertension induced by chronic renal adrenergic stimulation is angiotensin dependent.
Topics: Angiotensin II; Animals; Dogs; Female; Hypertension; Kidney; Norepinephrine; Posture; Renal Circulation; Renin; Sodium | 1995 |
Desensitization of vascular tissue to parathyroid hormone and parathyroid hormone-related protein.
Topics: Angiotensin II; Animals; Blood Vessels; Calcium; Cattle; Cells, Cultured; Cyclic AMP; Femoral Artery; Humans; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Rats; Vasodilator Agents | 1995 |
Angiotensin II: enhanced renal responsiveness in young genetically hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclic AMP; Glomerular Filtration Rate; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow | 1995 |
Insulin nonattenuation of vasoactive agent-induced responses in mesangial cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Endothelins; Glomerular Mesangium; Hypertension; Insulin; Intracellular Fluid; Male; Platelet Activating Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1995 |
[Effects of angiotensin II on spontaneous cytosolic calcium releases in ventricular myocytes of adult normal and hypertensive rats].
Topics: Angiotensin II; Animals; Calcium; Cytosol; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Sprague-Dawley | 1994 |
[Effects of angiotensin II and pressure on cellular fibronectin in the vascular wall in organotypic culture].
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Fibronectins; Fluorescent Antibody Technique; Gene Expression; Hypertension; Male; Rabbits | 1994 |
Blunted attenuation of angiotensin II-mediated Ca2+ transients by insulin in cultured unpassaged vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Endothelins; Hypertension; Insulin; Intracellular Fluid; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1995 |
Role of angiotensin II in cerebrovascular and renal damage in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Desoxycorticosterone; Disease Models, Animal; Enalapril; Hypertension; Kidney; Male; Rats; Rats, Wistar; Receptors, GABA-A; Renin-Angiotensin System; Sodium Chloride; Tetrazoles | 1995 |
Subpressor dose of angiotensin II increases susceptibility to the haemodynamic injury of blood pressure in Dahl salt-sensitive rats.
Topics: Angiotensin II; Animals; Cyclic AMP; Cyclic GMP; Eicosanoids; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Hemodynamics; Hypertension; Injections, Subcutaneous; Kidney; Lipid Peroxides; Radioimmunoassay; Rats | 1995 |
Angiotensinogen depletion by high renin levels in hypertensive rats: no evidence for tonic stimulation of angiotensinogen by angiotensin II.
Topics: Administration, Oral; Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Diet; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Renin; Sodium Chloride, Dietary; Tetrazoles | 1995 |
Antihypertensive and renal-protective effects of losartan in streptozotocin diabetic rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Glomerulosclerosis, Focal Segmental; Hypertension; Imidazoles; Kidney; Losartan; Male; Organ Size; Random Allocation; Rats; Rats, Inbred SHR; Tetrazoles | 1995 |
Endothelin production in cultured mesangial cells of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Cells, Cultured; Endothelins; Glomerular Mesangium; Hypertension; Imidazoles; Protein Kinase C; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Receptors, Vasopressin; Tetradecanoylphorbol Acetate | 1995 |
Opposing actions of angiotensin-(1-7) and angiotensin II in the brain of transgenic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Brain; Female; Hypertension; Immune Sera; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 1995 |
ANG II dependence of tubuloglomerular feedback responsiveness in hypertensive ren-2 transgenic rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Blood Pressure; Feedback; Glomerular Filtration Rate; Hemodynamics; Hydrostatic Pressure; Hypertension; Imidazoles; Kidney Glomerulus; Kidney Tubules; Male; Rats; Renal Circulation; Tetrazoles | 1995 |
Losartan for hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Humans; Hypertension; Imidazoles; Intestinal Absorption; Losartan; Tetrazoles | 1995 |
Renal, endocrine and vascular effects of atrial natriuretic peptide in a novel vasopressin-deficient genetically hypertensive strain of rat.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Animal; Endocrine Glands; Heart Rate; Hypertension; Kidney; Male; Rats; Rats, Inbred Strains; Sodium; Vasopressins; Water | 1995 |
Do we need more anti-hypertensive drugs: lessons from the new biology.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Genetic Markers; Humans; Hypertension; Meta-Analysis as Topic; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Rats; Treatment Outcome | 1995 |
Fos induced in brain of spontaneously hypertensive rats by angiotensin II and co-localization with AT-1 receptors.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain Chemistry; Hypertension; Hypothalamus; Immunohistochemistry; Phenylephrine; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Angiotensin; Saline Solution, Hypertonic; Solitary Nucleus | 1995 |
Exaggerated blood pressure response to angiotensin II in patients with Cushing's syndrome due to adrenocortical adenoma.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Cushing Syndrome; Diastole; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Male; Middle Aged; Reference Values; Renin | 1994 |
Nonmodulating trait may precede the development of hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Dopamine; Humans; Hypertension; Infusions, Intravenous; p-Aminohippuric Acid; Radioimmunoassay; Renal Circulation; Sodium; Sodium, Dietary | 1994 |
Renovascular resistance in primary hypertension: experimental variations detected by means of Doppler ultrasound.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Blood Pressure; Cardiac Output; Humans; Hypertension; Male; Middle Aged; p-Aminohippuric Acid; Pulsatile Flow; Renal Circulation; Ultrasonography; Vascular Resistance | 1994 |
Role of angiotensin II in extracellular matrix and transforming growth factor-beta 1 expression in hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Blotting, Northern; Captopril; Collagen; Extracellular Matrix; Gene Expression Regulation; Heart Ventricles; Hypertension; Male; Organ Size; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 1994 |
Blood pressure after captopril withdrawal from spontaneously hypertensive rats.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension; Rats; Rats, Inbred SHR | 1995 |
Cardiovascular effects of orally administered ABBOTT-81988, an angiotensin II antagonist, in conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Hypertension; Male; Nicotinic Acids; Rats; Rats, Inbred SHR; Tetrazoles | 1994 |
Accuracy of single concentration estimations of platelet angiotensin II receptor number. Its usefulness in screening for pregnancy-induced hypertension.
Topics: Adult; Angiotensin II; Blood Platelets; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Radioligand Assay; Receptors, Angiotensin | 1994 |
The impaired control of plasma renin activity in hypertensive patients with end-stage renal disease due to chronic glomerulonephritis.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Glomerulonephritis; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Kidney Failure, Chronic; Male; Middle Aged; Posture; Renin; Renin-Angiotensin System | 1994 |
Contribution of renal angiotensin II type I receptor to gene expressions in hypertension-induced renal injury.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Enalapril; Extracellular Matrix Proteins; Gene Expression; Hemodynamics; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 1994 |
[Comparative analysis of effects of prolonged peripheral and intracerebral administration of angiotensin-II to rats].
Topics: Angiotensin II; Animals; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Male; Rats; Rats, Wistar | 1994 |
Augmentation of angiotensin II release from isolated mesenteric arteries of Wistar-Kyoto and spontaneously hypertensive rats following nephrectomy.
Topics: Angiotensin II; Animals; Hypertension; In Vitro Techniques; Kidney; Male; Mesenteric Arteries; Nephrectomy; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 1994 |
Blunted inhibition by insulin of agonist-stimulated calcium, pH and aggregatory responses in platelets from hypertensive patients.
Topics: Adult; Angiotensin II; Blood Platelets; Blood Pressure; Calcium; Case-Control Studies; Cytosol; Endothelins; Female; Humans; Hydrogen-Ion Concentration; Hypertension; Insulin; Intracellular Fluid; Male; Middle Aged; Platelet Aggregation; Spectrometry, Fluorescence; Thrombin | 1994 |
Angiotensin II type 1 receptor messenger RNA levels in human blood cells of patients with primary and secondary hypertension: reference to renin profile.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Base Sequence; Blood Platelets; Blotting, Northern; Carcinoma, Renal Cell; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Kidney Neoplasms; Leukocytes, Mononuclear; Male; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Angiotensin; Renin; RNA, Messenger | 1994 |
Functional vascular renin-angiotensin system in hypertensive transgenic rats for the mouse renin gene Ren-2.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Hypertension; In Vitro Techniques; Male; Mice; Norepinephrine; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Vasoconstriction | 1994 |
Effect of chronic treatment with prazosin and L-arginine on the elevation of blood pressure during cold exposure.
Topics: Adrenal Glands; Angiotensin II; Animals; Arginine; Blood Pressure; Cardiomegaly; Cold Temperature; Epinephrine; Hypertension; Levodopa; Male; Prazosin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Physiological; Thyroid Hormones; Tyrosine 3-Monooxygenase | 1994 |
Parathyroid hormone-related peptide as a locally produced vasorelaxant: regulation of its mRNA by hypertension in rats.
Topics: Angiotensin II; Animals; Aorta; Gene Expression Regulation; Humans; Hypertension; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Norepinephrine; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium, Dietary; Teriparatide; Transcription, Genetic; Vasodilation | 1995 |
Angiotensin II Receptor Antagonists: Can they Go Beyond ACE Inhibitors? Proceedings of a satellite symposium to the 15th scientific meeting of the International Society of Hypertension. Melbourne, Australia, March 1994.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Tetrazoles | 1994 |
Quantitative localization of angiotensin II receptor subtypes in spontaneously hypertensive rats.
Topics: Adrenal Glands; Angiotensin II; Animals; Aorta, Thoracic; Autoradiography; Hypertension; Iodine Radioisotopes; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Rhombencephalon | 1994 |
Activated angiotensin II generation and regulation in rat mesenteric arteries following nephrectomy.
Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Feedback; Hypertension; Kidney; Male; Mesenteric Arteries; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles | 1994 |
Angiotensin II receptor antagonist, TCV-116, prevents myocardial hypertrophy in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Endomyocardial Fibrosis; Hypertension; Iodine Radioisotopes; Kinetics; Myocardium; Prodrugs; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles | 1994 |
Role of polyamines in hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Cardiomegaly; Disease Models, Animal; Heart Ventricles; Hypertension; Liver; Male; Mesenteric Arteries; Myocardium; Polyamines; Putrescine; Rats; Rats, Inbred WKY; Spermidine; Spermine | 1995 |
Interactions of cAMP-mediated vasodilators with angiotensin II in rat kidney during hypertension.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Angiotensin II; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Electromagnetic Phenomena; Fenoldopam; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Rheology; Vasoconstriction; Vasodilator Agents | 1993 |
Effects of fenoldopam on intracranial pressure and hemodynamic variables at normal and elevated intracranial pressure in anesthetized pigs.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia, General; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Central Venous Pressure; Cerebrovascular Circulation; Dopamine Agents; Dose-Response Relationship, Drug; Female; Fenoldopam; Heart Rate; Hemodynamics; Hypercapnia; Hypertension; Intracranial Pressure; Intraocular Pressure; Male; Ocular Hypertension; Pseudotumor Cerebri; Pulmonary Wedge Pressure; Swine; Vascular Resistance | 1994 |
Chronic effects of central and systemic administration of losartan on blood pressure and baroreceptor reflex in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Heart Rate; Hypertension; Imidazoles; Injections, Intraventricular; Injections, Subcutaneous; Losartan; Male; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex; Tetrazoles | 1994 |
Role of 21-deoxyaldosterone in human hypertension.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Pregnanes | 1994 |
Response to unilateral adrenalectomy for aldosterone-producing adenoma: effect of potassium levels and angiotensin responsiveness.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium | 1994 |
Different calcium storage pools in vascular smooth muscle cells from spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Angiotensin II; Animals; Calcium; Calcium-Transporting ATPases; Cytosol; Hypertension; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Terpenes; Thapsigargin | 1994 |
Glomerular losartan (DuP 753)-sensitive angiotensin II receptor density is increased in young spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Hypertension; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles | 1994 |
Low density lipoprotein isolated from patients with essential hypertension exhibits increased propensity for oxidation and enhanced uptake by macrophages: a possible role for angiotensin II.
Topics: Adult; Angiotensin II; Captopril; Enalapril; Female; Humans; Hypertension; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Male; Middle Aged | 1994 |
Enhanced 45Ca2+ efflux in cultured vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Calcium Radioisotopes; Calcium-Transporting ATPases; Carrier Proteins; Cells, Cultured; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Calcium Exchanger; Time Factors | 1994 |
Zona glomerulosa of the adrenal gland in a transgenic strain of rat: a morphologic and functional study.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Cell Size; Cholesterol; Cholesterol Esters; Female; Hyperaldosteronism; Hypertension; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Secretory Rate; Zona Glomerulosa | 1994 |
Enhanced pressor response to angiotensin III in spontaneously hypertensive rats: effects of losartan.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Hypertension; Imidazoles; Losartan; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 1994 |
Mesenteric vascular smooth muscle cells from spontaneously hypertensive rats display increased calcium responses to angiotensin II but not to endothelin-1.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Calcium; Cells, Cultured; Cytosol; Endothelins; Hypertension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 1994 |
Time course of losartan blockade of angiotensin II hypertension versus blockade of angiotensin II fast pressor effects.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Brain Stem; Heart Rate; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
Hypertension-related coronary thrombosis: prothrombic role of angiotensin II.
Topics: Angiotensin II; Blood Coagulation; Blood Coagulation Tests; Coronary Thrombosis; Humans; Hypertension; Risk Factors | 1994 |
Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Cerebral Cortex; Female; Hypertension; Hypothalamus; Medulla Oblongata; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin | 1994 |
Relation of pressor responsiveness to angiotensin II and insulin resistance in hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Glucose; Glucose Clamp Technique; Humans; Hypertension; Insulin Resistance; Male; Middle Aged; Muscle, Smooth, Vascular; Obesity; Pressoreceptors; Sodium, Dietary | 1994 |
Differential regulation of brain angiotensin II in genetically hypertensive and normotensive rats after nephrectomy.
Topics: Angiotensin II; Animals; Blood Pressure; Brain Chemistry; Hypertension; Male; Nephrectomy; Organophosphorus Compounds; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 1994 |
Abnormal atrial natriuretic peptide and renal responses to saline infusion in nonmodulating essential hypertensive patients.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Diet, Sodium-Restricted; Drug Resistance; Humans; Hypertension; Infusions, Intravenous; Kidney; Male; Phenotype; Sodium Chloride | 1994 |
Captopril inhibits the agonist-induced increase of cytosolic free Ca2+ in glomerular mesangial cells.
Topics: Angiotensin II; Animals; Biological Factors; Calcium; Captopril; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Glomerular Mesangium; Hypertension; Male; Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Type C Phospholipases | 1994 |
Autopotentiation of pressor responses by subpressor angiotensin II in rats.
Topics: Amino Acid Sequence; Anesthesia; Angiotensin II; Animals; Blood Pressure; Body Weight; Chloralose; Heart Rate; Hypertension; Injections, Intraperitoneal; Male; Molecular Sequence Data; Norepinephrine; Rats; Rats, Sprague-Dawley; Renin; Serotonin; Splanchnic Circulation; Vasopressins | 1994 |
Cushing's disease: evaluation of mineralocorticoid-induced hypertension.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Corticosterone; Cushing Syndrome; Desoxycorticosterone; Female; Humans; Hypertension; Hypokalemia; Mineralocorticoids; Pituitary Neoplasms; Renin | 1993 |
Cardiovascular effects of GR117289, a novel angiotensin AT1 receptor antagonist.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Callithrix; Dogs; Dose-Response Relationship, Drug; Hypertension; Hypertension, Renovascular; Injections, Intra-Arterial; Male; Nicotinic Acids; Rats; Rats, Inbred SHR; Tetrazoles | 1994 |
Effect of an angiotensin II receptor antagonist, CV-11974, and its prodrug, TCV-116, on production of aldosterone.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Corticosterone; Hypertension; Imidazoles; Infusions, Intravenous; Male; Pyridines; Rabbits; Rats; Rats, Inbred SHR; Rats, Wistar; Tetrazoles; Zona Glomerulosa | 1994 |
Nifedipine reduces pressor responsiveness to angiotensin II in pregnant women.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors | 1994 |
Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficient rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Kininogens; Kinins; Male; Molecular Weight; Rats; Sodium; Spironolactone | 1994 |
Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension.
Topics: Adult; Aged; Angiotensin II; Base Sequence; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 3; Female; Genetic Linkage; Humans; Hypertension; Male; Middle Aged; Molecular Sequence Data; Polymorphism, Genetic; Receptors, Angiotensin | 1994 |
Effect of acute hypertension in the coronary circulation: role of mechanical factors and oxygen radicals.
Topics: Angiotensin II; Animals; Biomechanical Phenomena; Blood Pressure; Catalase; Coronary Circulation; Deferoxamine; Dogs; Drug Synergism; Female; Free Radicals; Hypertension; Male; Phenylephrine; Reactive Oxygen Species; Serotonin; Superoxide Dismutase; Vasoconstriction | 1994 |
Role of angiotensin II in renal injury of deoxycorticosterone acetate-salt hypertensive rats.
Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Collagen; Desoxycorticosterone; Enalapril; Hypertension; Kidney; Kidney Diseases; Male; Organ Size; Rats; Rats, Wistar; Renin; RNA, Messenger; Sodium Chloride; Tetrazoles; Transforming Growth Factor beta | 1994 |
Pregnancy-induced hypertension in rats with early adriamycin nephropathy.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Doxorubicin; Female; Hypertension; Nephrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylacetates; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Wistar; Receptors, Thromboxane; Sulfonamides | 1994 |
Vasoconstrictor responses to components of the renin-angiotensin system in cyclosporin-induced hypertension in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cyclosporine; Female; Hypertension; In Vitro Techniques; Mesenteric Arteries; Rats; Rats, Wistar; Renin-Angiotensin System; Sensitivity and Specificity; Vascular Resistance; Vasoconstriction | 1994 |
Differential regulation of uterine and glomerular angiotensin II receptors in normal and hypertensive pregnancy in the rat.
Topics: Angiotensin II; Animals; Female; Hypertension; Kidney Glomerulus; Kinetics; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Uterus | 1994 |
Primary hyperparathyroidism and hypertension: persistently abnormal pressor sensitivity in normotensive patients after surgical cure.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Calcium; Female; Humans; Hyperparathyroidism; Hypertension; Male; Middle Aged; Norepinephrine; Prospective Studies | 1994 |
Pulsatile cerebral perfusion pressure: significance for cerebral blood flow.
Topics: Anesthesia, General; Angiotensin II; Animals; Blood Pressure; Cats; Cerebral Arteries; Cerebrovascular Circulation; Homeostasis; Hypertension; Intracranial Pressure; Pulsatile Flow; Trimethaphan; Vascular Resistance | 1994 |
Endogenous angiotensin II enhances phenylephrine-induced tone in hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Hypertension; Imidazoles; Indoles; Losartan; Mesenteric Arteries; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Tetrazoles; Vasomotor System | 1994 |
[The effect of the one-time and long-term administration of preparations acting on biogenic amine metabolism on the blood level of pressor peptide hormones].
Topics: Adolescent; Adult; Angiotensin II; Biogenic Amines; Blood Pressure; Bromocriptine; Chronic Disease; Cyproheptadine; Drug Evaluation; Female; Humans; Hypertension; Hypothalamic Diseases; Male; Middle Aged; Syndrome; Time Factors; Vasopressins | 1993 |
Modification of pressure natriuresis by long-term losartan in spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Drug Administration Schedule; Glomerular Filtration Rate; Hypertension; Imidazoles; Kidney; Losartan; Male; Natriuresis; Random Allocation; Rats; Rats, Inbred SHR; Renal Artery; Renal Circulation; Tetrazoles | 1994 |
Alterations of cerebromicrovascular Na+,K(+)-ATPase activity due to fatty acids and acute hypertension.
Topics: 4-Nitrophenylphosphatase; Acute Disease; Angiotensin II; Animals; Arachidonic Acid; Brain; Capillaries; Cerebrovascular Circulation; Fatty Acids; Fatty Acids, Unsaturated; gamma-Glutamyltransferase; Hypertension; Male; Phosphoric Monoester Hydrolases; Potassium; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 1993 |
The pharmacological characterization of FK 739, a new angiotensin II-receptor antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bronchial Diseases; Cattle; Cell Membrane; Cerebellum; Dogs; Edema; Guinea Pigs; Hypertension; Hypertension, Renovascular; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rabbits; Rats; Rats, Inbred SHR; Rats, Wistar | 1993 |
Reduced left ventricular distensibility in normotensive men with a positive family history of hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Electrocardiography; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Phonocardiography; Renin; Sodium; Ventricular Function, Left | 1993 |
Cardiovascular effects of angiotensin III in brainstem nuclei of normotensive and hypertensive rats.
Topics: Angiotensin II; Angiotensin III; Animals; Blood Pressure; Brain Stem; Heart Rate; Hypertension; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1994 |
Defective modulation of angiotensin II-induced renal vasoconstriction in hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Epoprostenol; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1994 |
Diagnostic value of captopril test in hypertensive patients with renal artery stenosis.
Topics: Adult; Angiography; Angiotensin II; Blood Pressure; Captopril; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Renovascular; Kidney; Male; Middle Aged; Radioisotope Renography; Renal Artery; Renal Artery Obstruction; Renin; Sensitivity and Specificity; Sodium Chloride, Dietary; Urography | 1994 |
Role of anterior hypothalamic angiotensin II in the pathogenesis of salt sensitive hypertension in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Cells, Cultured; Hypertension; Hypothalamus, Anterior; Imidazoles; Losartan; Male; Microinjections; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Sodium Chloride; Tetrazoles | 1994 |
The hypoxic moderation of systemic hypertension in spontaneously hypertensive rats.
Topics: Altitude; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Blood Pressure; Hypertension; Hypoxia; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin | 1993 |
Kinins contribute to the improvement of insulin sensitivity during treatment with angiotensin converting enzyme inhibitor.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Weight; Bradykinin; Doxazosin; Enalapril; Glucose Clamp Technique; Hypertension; Imidazoles; Insulin; Kinins; Losartan; Male; Potassium; Rats; Rats, Inbred SHR; Sodium; Tetrazoles | 1994 |
Increased intracellular calcium response in glomerular mesangial cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Glomerular Mesangium; Hypertension; Intracellular Fluid; Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Terpenes; Thapsigargin | 1993 |
Identification of AT1 receptors on human platelets and decreased angiotensin II binding in hypertension.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Humans; Hypertension; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Middle Aged; Oligopeptides; Receptors, Angiotensin; Tetrazoles | 1993 |
Effect of increasing doses of angiotensin II infused into normal and hypertensive Wistar rats on low density lipoprotein and fibrinogen uptake by aortic walls.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Fibrinogen; Hypertension; Lipoproteins, LDL; Male; Metabolic Clearance Rate; Rats; Rats, Inbred SHR; Rats, Wistar | 1994 |
Altered pressure natriuresis in chronic angiotensin II hypertension in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Chronic Disease; Hypertension; Imidazoles; Losartan; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Reference Values; Tetrazoles | 1994 |
Acute sodium loading in patients with uncomplicated diabetes mellitus: renal and hormonal effects.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Norepinephrine; Peptides; Renin; Renin-Angiotensin System; Sodium | 1994 |
Vascular reactivity to angiotensin II is selectively enhanced in the kidneys of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Captopril; Cardiac Output; Heart Rate; Hypertension; Infusions, Intravenous; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Vascular Diseases; Vascular Resistance | 1994 |
Sodium physiopathology and 'nonmodulating' hypertension.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Drug Resistance; Humans; Hydrocortisone; Hypertension; Italy; Phenotype; Renal Circulation; Renin-Angiotensin System; Sodium; Sodium, Dietary | 1994 |
Platelet angiotensin II binding in pregnant women with chronic hypertension.
Topics: Adolescent; Adult; Angiotensin II; Chronic Disease; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third | 1994 |
Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Hydralazine; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Signal Transduction; Tetrazoles | 1994 |
Modification of mesangial cell function by chloride is attenuated in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Chlorides; Dinoprostone; Glomerular Mesangium; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Vasopressins | 1994 |
Mechanisms of hypertension in transgenic rats expressing the mouse Ren-2 gene.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Arginine; Biphenyl Compounds; Blood Pressure; Endothelins; Female; Gene Expression; Hemodynamics; Hypertension; Imidazoles; Lisinopril; Losartan; Mice; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reference Values; Tetrazoles | 1994 |
Cerebrovascular autoregulation in response to hypertension induced by NG-nitro-L-arginine methyl ester.
Topics: Angiotensin II; Animals; Arginine; Autoradiography; Blood Pressure; Brain; Cerebrovascular Circulation; Glucose; Homeostasis; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley | 1994 |
Hypertension and thirst outlasting renal vasoconstriction as effects of a brief evaluation of systemic angiotensin II in sheep.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Infusions, Intra-Arterial; Infusions, Intravenous; Labetalol; Regional Blood Flow; Renal Artery; Sheep; Thirst; Time Factors; Vasoconstriction | 1994 |
Pertussis toxin normalizes enhanced renovascular responses to angiotensin II in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; GTP-Binding Proteins; Hypertension; Kidney; Male; Pertussis Toxin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Virulence Factors, Bordetella | 1994 |
TCV-116, a newly developed angiotensin II receptor antagonist, induces regression of cardiac hypertrophy through suppression of the tissue renin-angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Heart Atria; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Organ Size; Rats; Rats, Inbred SHR; Renin; Tetrazoles | 1994 |
Angiotensin II and alpha 1-adrenergic tone in chronic nitric oxide blockade-induced hypertension.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Glomerular Filtration Rate; Hematocrit; Hypertension; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Angiotensin; Reference Values; Regional Blood Flow; Renal Circulation; Tetrazoles; Vascular Resistance | 1994 |
Angiotensin II alters aortic fibronectin independently of hypertension.
Topics: Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Fibronectins; Humans; Hydralazine; Hypertension; Imidazoles; Losartan; Male; Prazosin; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles | 1994 |
Clonidine reverses the slowly developing hypertension produced by low doses of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Clonidine; Hypertension; Male; Rats; Rats, Sprague-Dawley | 1994 |
A kallikrein-like enzyme in the aorta of normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Desoxycorticosterone; Hypertension; Kallikreins; Male; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Reference Values; Sodium Chloride; Systole | 1994 |
The neurogenic origin of hypertension in SHR may be mediated by angiotensin II through a receptor different from AT1 and AT2.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Hypertension; Imidazoles; Injections, Intraventricular; Losartan; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles | 1993 |
[Mechanisms of vascular hypertrophy in hypertension].
Topics: Angiotensin II; Animals; Endothelial Growth Factors; Endothelium, Vascular; Humans; Hypertension; Hypertrophy; Muscle, Smooth, Vascular; Vascular Resistance | 1993 |
Microvascular mechanisms of change in tumor blood flow due to angiotensin II, epinephrine, and methoxamine: a functional morphometric study.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Capillaries; Diffusion Chambers, Culture; Epinephrine; Hypertension; Male; Methoxamine; Microcirculation; Rats; Regional Blood Flow; Skin | 1993 |
Concentration-dependent effects of insulin on Ca2+ influx in vascular smooth muscle cells of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Hypertension; Insulin; Male; Muscle, Smooth, Vascular; Nifedipine; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Are free radicals involved in the pathobiology of human essential hypertension?
Topics: Adult; Angiotensin II; Catalase; Erythrocytes; Female; Free Radicals; Humans; Hydrogen Peroxide; Hypertension; In Vitro Techniques; Lipid Peroxides; Male; Malondialdehyde; Middle Aged; Neutrophils; Nitric Oxide; Reference Values; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances; Vitamin E | 1993 |
Long-term low-dose angiotensin converting enzyme inhibitor treatment increases vascular cyclic guanosine 3',5'-monophosphate.
Topics: Aging; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Bradykinin; Cyclic GMP; Dose-Response Relationship, Drug; Female; Hypertension; In Vitro Techniques; Indoles; Maternal-Fetal Exchange; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Perindopril; Pregnancy; Ramipril; Rats; Rats, Inbred SHR; Reference Values; Systole | 1993 |
Pressure-independent baroreflex resetting produced by chronic infusion of angiotensin II in rabbits.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Nitroprusside; Phenylephrine; Pressoreceptors; Rabbits; Reflex; Time Factors | 1993 |
Angiotensin II-induced increases in platelet intracellular free calcium in hypertensive and normotensive pregnancy.
Topics: Angiotensin II; Blood Platelets; Calcium; Female; Humans; Hypertension; Magnesium; Pregnancy; Pregnancy Complications, Cardiovascular; Pressoreceptors; Pyrrolidonecarboxylic Acid | 1993 |
Effect of captopril on vasoconstriction and Ca2+ fluxes in aortic smooth muscle.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Thoracic; Bradykinin; Calcium; Calcium Channels; Captopril; Cells, Cultured; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enalaprilat; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vasoconstriction | 1993 |
Effects of angiotensin II and endothelin-1 on platelet aggregation and cytosolic pH and free Ca2+ concentrations in essential hypertension.
Topics: Adult; Aged; Amiloride; Analysis of Variance; Angiotensin II; Blood Platelets; Calcium; Cytosol; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Female; Humans; Hydrogen-Ion Concentration; Hypertension; In Vitro Techniques; Male; Middle Aged; Peptides, Cyclic; Platelet Aggregation; Receptor, Endothelin A; Receptors, Endothelin; Regression Analysis; Saralasin | 1993 |
Studies of cardiovascular responses to some endogenous pressor and hypotensive agents in conscious stroke-prone spontaneously hypertensive rats of different ages.
Topics: Acetylcholine; Adenosine; Age Factors; Angiotensin II; Animals; Blood Pressure; Cardiovascular Agents; Cerebrovascular Disorders; Heart Rate; Hemodynamics; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Chromosomal assignment of human and rat hypertension candidate genes: type 1 angiotensin II receptor genes and the SA gene.
Topics: Angiotensin II; Animals; Chromosome Mapping; Chromosomes, Human, Pair 16; Coenzyme A Ligases; Humans; Hypertension; Mice; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1993 |
Vascular conversion of angiotensin I in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Hindlimb; Hypertension; Male; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Effect of captopril on renal extraction of renin, angiotensin II, atrial natriuretic peptide and vasopressin, and renal vein renin ratio in patients with arterial hypertension and unilateral renal artery disease.
Topics: Adult; Aged; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Captopril; Female; Hormones; Humans; Hypertension; Kidney; Male; Middle Aged; Peptides; Renal Artery Obstruction; Renal Circulation; Renin; Veins | 1993 |
Renal response to amino acid infusion in essential hypertension.
Topics: Adult; Aged; Aldosterone; Amino Acids; Angiotensin II; Blood Pressure; Diastole; Diet, Sodium-Restricted; Enalapril; Female; Glomerular Filtration Rate; Humans; Hypertension; Infusions, Intravenous; Kidney; Male; Middle Aged; Regional Blood Flow; Renin; Sodium; Systole; Urine | 1994 |
Pressor mechanisms in adriamycin-induced nephropathy with hypertension in rats.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Cholesterol; Creatinine; Doxorubicin; Hypertension; Imidazoles; Kidney; Kidney Failure, Chronic; Losartan; Male; Nephrotic Syndrome; Potassium; Rats; Rats, Wistar; Serum Albumin; Sodium; Tetrazoles; Time Factors; Urea; Vasopressins | 1994 |
DuP 753 is more effective than captopril on baroreceptor function in high-renin hypertension.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Heart Rate; Hypertension; Imidazoles; Losartan; Male; Phenylephrine; Pressoreceptors; Rats; Rats, Wistar; Reflex; Renin; Tetrazoles; Time Factors | 1994 |
Chronic converting enzyme inhibition facilitates baroreceptor resetting to hypertensive levels.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Enalapril; Hypertension; Imidazoles; Losartan; Male; Pressoreceptors; Rats; Rats, Wistar; Reference Values; Regression Analysis; Tetrazoles | 1994 |
Angiotensin receptor sites in renal vasculature of rats developing genetic hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Blood Vessels; Hemodynamics; Hypertension; Imidazoles; Losartan; Microcirculation; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Tetrazoles; Vasoconstriction | 1993 |
Quinapril prevents stroke both during and after the treatment period in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Height; Body Weight; Brain; Cerebrovascular Disorders; Diuresis; Heart Rate; Hypertension; Incidence; Isoquinolines; Kidney; Male; Myocardium; Proteinuria; Quinapril; Rats; Rats, Inbred SHR; Risk Factors; Tetrahydroisoquinolines; Time Factors | 1993 |
AII receptor number and screening for PIH.
Topics: Angiotensin II; Blood Platelets; Female; Humans; Hypertension; Mass Screening; Pregnancy; Pregnancy Complications, Cardiovascular; Receptors, Angiotensin | 1993 |
Regulation of aldosterone secretion in hypertensive blacks.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Black People; Female; Humans; Hypertension; Male; Middle Aged; Renin; White People | 1994 |
Slow developing pressor effect of angiotensin II and vascular structure.
Topics: Angiotensin II; Animals; Blood Vessels; Growth Substances; Hypertension; Hypertrophy; Rats; Rats, Inbred SHR | 1993 |
Abnormality of the glomerular angiotensin II receptor in experimental diabetic nephropathy.
Topics: Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerulonephritis, IGA; Hypertension; Kidney Glomerulus; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 1993 |
Elevated sympathetic nerve activity in patients with accelerated essential hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension; Male; Renin; Sympathetic Nervous System | 1993 |
Effect of perindopril on cardiovascular hypertrophy of the SHR: respective roles of reduced blood pressure and reduced angiotensin II levels.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Indoles; Male; Muscle, Smooth, Vascular; Perindopril; Rats; Rats, Inbred SHR | 1993 |
Effects of blockade of AT1 and AT2 receptors in brain on the central angiotensin II pressor response in conscious spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Brain; Heart Rate; Hypertension; Imidazoles; Injections, Intraventricular; Losartan; Male; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles; Vascular Resistance | 1993 |
Prevention of genetic hypertension by early treatment of spontaneously hypertensive rats with the angiotensin converting enzyme inhibitor captopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Inbred SHR | 1993 |
Impaired recovery of vascular smooth muscle intracellular calcium following agonist stimulation in insulin resistant (Zucker obese) rats.
Topics: Angiotensin II; Animals; Aorta; Arginine Vasopressin; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Fluorometry; Fura-2; Hypertension; Insulin; Insulin Resistance; Male; Muscle, Smooth, Vascular; Obesity; Rats; Rats, Zucker; Sarcoplasmic Reticulum; Time Factors; Vasoconstriction; Vasodilation | 1993 |
Rat angiotensin II (type 1A) receptor mRNA regulation and subtype expression in myocardial growth and hypertrophy.
Topics: Angiotensin II; Animals; Base Sequence; Cardiomegaly; Heart; Hypertension; Male; Molecular Sequence Data; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger | 1993 |
Relationship between mean arterial pressure and parameters derived from blood flow velocity waveforms in the systemic circulation of fetal sheep.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Flow Velocity; Blood Pressure; Embryonic and Fetal Development; Female; Fetus; Hypertension; Norepinephrine; Pregnancy; Pulsatile Flow; Sheep; Ultrasonography, Prenatal | 1993 |
Alterations in vascular structure and function after short-term losartan treatment in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Hydralazine; Hypertension; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Tetrazoles; Vasoconstriction | 1993 |
Morphology of resistance arteries and comparison of effects of vasoconstrictors in mild essential hypertensive patients.
Topics: Adult; Angiotensin II; Arginine Vasopressin; Arteries; Endothelins; Humans; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Serotonin; Vascular Resistance; Vasoconstrictor Agents | 1993 |
Control of blood pressure and end-organ damage in maturing salt-loaded stroke-prone spontaneously hypertensive rats by oral angiotensin II receptor blockade.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Proteins; Body Weight; Brain; Chlorides; Creatinine; Diuresis; Hypertension; Imidazoles; Kidney; Losartan; Male; Myocardium; Organ Size; Osmolar Concentration; Potassium; Proteinuria; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Sodium; Tetrazoles | 1993 |
Effects of the blockade of the renin-angiotensin system in cyclosporin-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antibodies; Cilazapril; Cyclosporine; Female; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Male; Renin; Renin-Angiotensin System; Saimiri | 1993 |
Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II, and calcium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Glands; Angiotensin II; Animals; Animals, Genetically Modified; Calcimycin; Calcium; Cyclic AMP; Disease Models, Animal; Enzyme Precursors; Female; Hypertension; Male; Mice; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1993 |
The angiotensin I converting enzyme gene and predisposition to high blood pressure.
Topics: Adult; Aldosterone; Alleles; Angiotensin II; Blood Pressure; Diastole; Family; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Middle Aged; Parents; Peptidyl-Dipeptidase A; Renin; Systole | 1993 |
Angiotensin II type 2 receptor expression in neuronal cultures from spontaneously hypertensive rat brain.
Topics: Angiotensin II; Animals; Brain Stem; Cells, Cultured; Cyclic GMP; Hypertension; Hypothalamus; Neurons; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tumor Cells, Cultured | 1993 |
Increased alpha 1-adrenergic vascular sensitivity during development of hypertension in conscious dogs.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cell Membrane; Consciousness; Dogs; Female; Hypertension; Male; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Vascular Resistance; Vasoconstriction; Vasopressins | 1993 |
Indirect evidence for vascular uptake of circulating renin in hypertensive patients.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Vessels; Female; Forearm; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Male; Middle Aged; Receptors, Adrenergic, beta; Regional Blood Flow; Renin; Renin-Angiotensin System | 1993 |
The effect of angiotensin II on platelet intracellular free magnesium and calcium ionic concentrations in essential hypertension.
Topics: Adult; Aged; Angiotensin II; Blood Platelets; Calcium; Female; Humans; Hypertension; Magnesium; Male; Middle Aged | 1993 |
In vivo pharmacology of SC-51316, a nonpeptidic angiotensin II receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Enalapril; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Tetrazoles; Triazoles | 1993 |
Cerebral blood flow and cerebral blood flow velocity during angiotensin-induced arterial hypertension in dogs.
Topics: Angiotensin II; Animals; Basilar Artery; Blood Flow Velocity; Brain Stem; Cerebellum; Cerebral Cortex; Cerebrovascular Circulation; Dogs; Echoencephalography; Hypertension; Male; Pulsatile Flow | 1993 |
Hypertensive rats produced by in vivo introduction of the human renin gene.
Topics: Angiotensin II; Animals; Disease Models, Animal; Gene Transfer Techniques; Histidine; Humans; Hypertension; Male; Morpholines; Rats; Rats, Wistar; Renin | 1993 |
Angiotensin II, sodium, and cardiovascular hypertrophy in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Hypertension; Indoles; Male; Perindopril; Rats; Rats, Inbred SHR; Sodium | 1993 |
Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomyopathies; Fibrosis; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Male; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Spironolactone | 1993 |
Regional angiotensin II production in essential hypertension and renal artery stenosis.
Topics: Adult; Angiotensin I; Angiotensin II; Arteries; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Renal Artery Obstruction; Tissue Distribution; Veins | 1993 |
Nonpeptide angiotensin AT1 and AT2 receptor ligands modulate the upper limit of cerebral blood flow autoregulation in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebrovascular Circulation; Homeostasis; Hypertension; Imidazoles; Laser-Doppler Flowmetry; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1993 |
Coronary microvascular fluid flux and permeability: influence of angiotensin II, aldosterone, and acute arterial hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Capillary Permeability; Coronary Vessels; Dogs; Female; Heart; Hemodynamics; Hypertension; Lymph; Lymphatic System; Male; Methoxamine; Myocardium; Ventricular Function, Left | 1993 |
High sensitivity of hypertensive aortic myocytes to norepinephrine and angiotensin.
Topics: Angiotensin II; Animals; Aorta; Aorta, Thoracic; Diaphragm; Hypertension; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Vasopressins | 1993 |
Ventrolateral medulla in spontaneously hypertensive rats: role of angiotensin II.
Topics: Angiotensin II; Animals; Bicuculline; Hemodynamics; Hypertension; Male; Medulla Oblongata; Microinjections; Muscimol; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Lack of effect of calcium carbonate supplementation on 24h blood pressure, angiotensin II reactivity and PTH(1-84) in essential hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Calcium Carbonate; Humans; Hypertension; Middle Aged; Parathyroid Hormone | 1993 |
Enhanced renal angiotensin II subtype 1 receptor responses in the spontaneously hypertensive rat.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Captopril; Diuresis; Hypertension; Kidney; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Sodium | 1993 |
Direct vasopressor effects of erythropoietin in genetically hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Body Weight; Erythropoietin; Hematocrit; Hypertension; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1993 |
Central neural mechanism contributing to attenuation of angiotensin II-induced hypertension in rats on dietary calcium supplementation.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Calcium, Dietary; Central Nervous System; Diuresis; Heart Rate; Hypertension; Male; Methoxyhydroxyphenylglycol; Natriuresis; Norepinephrine; Rats; Rats, Wistar | 1993 |
Angiotensin II-induced tachyphylaxis in aortas of normo- and hypertensive rats: changes in receptor affinity.
Topics: Angiotensin II; Animals; Aorta; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tachyphylaxis | 1993 |
Pressor reactivity to norepinephrine and angiotensin in salt-sensitive hypertensive patients.
Topics: Adult; Angiotensin II; Black People; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Sodium, Dietary | 1993 |
Effect of chronic treatment with losartan potassium (DuP 753) on the elevation of blood pressure during chronic exposure of rats to cold.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Catecholamines; Cold Temperature; Eating; Hypertension; Imidazoles; Losartan; Male; Organ Size; Rats; Rats, Sprague-Dawley; Tetrazoles | 1993 |
Cardiovascular remodeling and its correction: toward a comprehensive strategy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiovascular Diseases; Cilazapril; Humans; Hypertension | 1993 |
Functional roles of brain AT1 and AT2 receptors in the central angiotensin II pressor response in conscious young spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Brain; Disease Models, Animal; Heart Rate; Hypertension; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Vasopressins | 1993 |
Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Bone Marrow; Capillary Permeability; Carcinoma 256, Walker; Female; Hypertension; Maleic Anhydrides; Methylglucosides; Polystyrenes; Rats; Rats, Wistar; Serum Albumin, Bovine; Tissue Distribution; Zinostatin | 1993 |
Modification of tumour blood flow using the hypertensive agent, angiotensin II.
Topics: Angiotensin II; Animals; Hypertension; Male; Neoplasms, Experimental; Perfusion; Rats; Rats, Inbred Strains; Regional Blood Flow | 1993 |
Effect of angiotensin II induced hypertension on tumor blood flow and interstitial fluid pressure.
Topics: Adenocarcinoma; Angiotensin II; Animals; Blood Pressure; Colonic Neoplasms; Extracellular Space; Female; Fibrosarcoma; Hypertension; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; Mice, SCID; Microcirculation; Neoplasms; Regional Blood Flow; Specific Pathogen-Free Organisms; Tumor Cells, Cultured; Vascular Resistance | 1993 |
Blood pressure responses after carotid surgery: relationship to postoperative baroreceptor sensitivity.
Topics: Aged; Analysis of Variance; Angiotensin II; Blood Pressure; Blood Pressure Determination; Endarterectomy, Carotid; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Nitroglycerin; Postoperative Period; Pressoreceptors; Prospective Studies; Valsalva Maneuver | 1993 |
Dependence of angiotensin production in transgenic mice carrying either the human renin or human angiotensinogen genes on species-specific kinetics of the renin-angiotensin system.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Hypertension; Kidney; Kinetics; Liver; Mice; Mice, Transgenic; Molecular Sequence Data; Renin; Renin-Angiotensin System; Species Specificity | 1993 |
Atrial natriuretic peptide in non-modulating essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Diet, Sodium-Restricted; Hormones; Humans; Hypertension; Kidney; Male; Middle Aged; p-Aminohippuric Acid; Renin; Sodium | 1993 |
Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function.
Topics: Angiotensin II; Coronary Thrombosis; Dose-Response Relationship, Drug; Fibrinolysis; Humans; Hypertension; Infusions, Intravenous; Plasminogen Activator Inhibitor 1; Renin-Angiotensin System; Risk Factors; Time Factors; Tissue Plasminogen Activator | 1993 |
Alterations in prostaglandin production in spontaneously hypertensive rat smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Dinoprostone; Epoprostenol; Hypertension; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 1993 |
Sodium and angiotensin in hypertension induced by long-term nitric oxide blockade.
Topics: Angiotensin II; Animals; Arginine; Biphenyl Compounds; Diet, Sodium-Restricted; Electrolytes; Hemodynamics; Hypertension; Imidazoles; Losartan; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Renin-Angiotensin System; Tetrazoles; Time Factors | 1993 |
Angiotensin blockade and the progression of renal damage in the spontaneously hypertensive rat.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chromatography, High Pressure Liquid; Hydralazine; Hypertension; Indans; Kidney; Male; Proteinuria; Rats; Rats, Inbred SHR; Survival Analysis; Tetrazoles | 1993 |
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Hydralazine; Hydrochlorothiazide; Hypertension; Linear Models; Muscle Contraction; Muscle, Smooth, Vascular; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1995 |
Effect of an antihypertensive drug on brain angiotensin II levels in renal and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain Chemistry; Chromatography, High Pressure Liquid; Hydralazine; Hypertension; Hypertension, Renovascular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Renin-Angiotensin System | 1995 |
Angiotensins differentially activate phospholipase D in vascular smooth muscle cells from spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Angiotensin II; Animals; Cells, Cultured; Enzyme Activation; Hypertension; Muscle, Smooth, Vascular; Phospholipase D; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1995 |
Effect of high-salt intake on blood pressure and vascular reactivity of diabetic rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Diabetes Mellitus, Experimental; Hypertension; Male; Norepinephrine; Rats; Rats, Wistar; Sodium, Dietary; Vasoconstrictor Agents | 1995 |
Breakdown of blood pressure and body fluid homeostasis in heart transplant recipients.
Topics: Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Case-Control Studies; Cyclosporine; Female; Heart; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Liver Transplantation; Male; Middle Aged; Renin-Angiotensin System; Sodium Chloride; Sodium, Dietary; Ventricular Function, Left; Water-Electrolyte Balance; Water-Electrolyte Imbalance | 1996 |
Brain angiotensin II contributes to the development of hypertension in Dahl-Iwai salt-sensitive rats.
Topics: Angiotensin II; Animals; Arteries; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Drug Resistance; Heart Rate; Hormones; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Sodium Chloride; Tetrazoles | 1995 |
Lack of involvement of bradykinin in the vascular sympathoinhibitory effects of angiotensin converting enzyme inhibitors in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Decerebrate State; Hemodynamics; Hypertension; Imidazoles; Indoles; Losartan; Male; Muscle, Smooth, Vascular; Perindopril; Rats; Rats, Inbred SHR; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Vasoconstriction | 1995 |
Haemodynamic effects of losartan and the endothelin antagonist, SB 209670, in conscious, transgenic ((mRen-2)27), hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Endothelin Receptor Antagonists; Endothelins; Hemodynamics; Hypertension; Imidazoles; Indans; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Regional Blood Flow; Tetrazoles | 1995 |
Acute hypertension activates mitogen-activated protein kinases in arterial wall.
Topics: Acute Disease; Angiotensin II; Animals; Aorta; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; DNA Primers; Enzyme Activation; Gene Expression; Genes, fos; Genes, jun; Hypertension; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phenylephrine; Rats; Rats, Wistar; Restraint, Physical; RNA, Messenger; Transcription Factor AP-1; Up-Regulation | 1996 |
Effects of endothelin-1 on the contractility of cardiomyocytes from the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelins; Heart Ventricles; Hypertension; Isotonic Contraction; Myocardial Contraction; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents | 1995 |
Losartan: the first angiotensin receptor antagonist in clinical use.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Tetrazoles | 1995 |
Effects of losartan on insulin sensitivity in severe hypertension: connections through sympathetic nervous system activity?
Topics: Adult; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Viscosity; Glucose Clamp Technique; Humans; Hypertension; Imidazoles; Insulin Resistance; Losartan; Male; Sympathetic Nervous System; Tetrazoles | 1995 |
Converting enzyme inhibition and its withdrawal in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Hypertension; Indoles; Male; Peptide Fragments; Perindopril; Radioimmunoassay; Rats; Rats, Inbred SHR; Renin; Tissue Distribution | 1995 |
Plasma levels of beta-endorphin, leucine enkephalin and arginine vasopressin in patients with essential hypertension and the effects of clonidine.
Topics: Angiotensin II; Antihypertensive Agents; Arginine Vasopressin; beta-Endorphin; Blood Pressure; Clonidine; Enkephalin, Leucine; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Naloxone; Narcotic Antagonists; Neurotensin; Renin; Time Factors | 1995 |
Nitric oxide and the depressor response to angiotensin blockade in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Coarctation; Arginine; Biphenyl Compounds; Blood Pressure; Hypertension; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ramipril; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Vasoconstrictor Agents | 1996 |
Kinin-mediated antihypertensive effect of captopril in deoxycorticosterone acetate-salt hypertension.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Desoxycorticosterone; Hypertension; Kinins; Male; Nephrectomy; Rats; Rats, Wistar; Reference Values; Renal Circulation; Sodium Chloride; Time Factors | 1996 |
Regulation of norepinephrine transport system by angiotensin II in neuronal cultures of normotensive and spontaneously hypertensive rat brains.
Topics: Angiotensin II; Animals; Autoradiography; Base Sequence; Brain; Carrier Proteins; Cells, Cultured; Hypertension; Kinetics; Molecular Probes; Molecular Sequence Data; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; RNA, Messenger; Symporters | 1996 |
Role of vasoconstrictors in the systemic hypertension of rats acclimatized to hypoxia.
Topics: Acclimatization; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Hypoxia; Male; Phentolamine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 1995 |
Effects of long-term treatment with angiotensin-converting enzyme inhibitor on angiotensin II and prostacyclin release from mesenteric arteries in spontaneously hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Epoprostenol; Hypertension; Isoproterenol; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred SHR; Vasodilation | 1995 |
Angiotensin II-dependent down-regulation of vascular natriuretic peptide type C receptor gene expression in hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Down-Regulation; Guanylate Cyclase; Hypertension; Male; Muscle, Smooth, Vascular; Natriuretic Peptide, C-Type; Nitrobenzenes; Piperazines; Proteins; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetrazoles | 1996 |
New angiotensin-II blocker.
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Diuretics; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Losartan; Male; Tetrazoles | 1996 |
Adverse influence of systemic vascular stiffening on cardiac dysfunction and adaptation to acute coronary occlusion.
Topics: Acute Disease; Angiotensin II; Animals; Blood Vessels; Cardiac Output; Compliance; Coronary Circulation; Disease Models, Animal; Dogs; Female; Hemodynamics; Hypertension; Male; Myocardial Infarction; Myocardial Ischemia; Vascular Resistance | 1996 |
Vascular smooth muscle polyploidy and cardiac hypertrophy in genetic hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cardiomegaly; Female; Hypertension; Imidazoles; Indoles; Losartan; Male; Muscle, Smooth, Vascular; Perindopril; Polyploidy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 1996 |
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.
Topics: Acetylcholine; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Arginine; Biphenyl Compounds; Calcimycin; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tetrazoles | 1996 |
Ca(2+)-dependent mitogen-activated protein kinase activation in spontaneously hypertensive rat vascular smooth muscle defines a hypertensive signal transduction phenotype.
Topics: Angiotensin II; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cells, Cultured; Dual Specificity Phosphatase 1; Enzyme Activation; Hypertension; Immediate-Early Proteins; Muscle, Smooth, Vascular; Phosphoprotein Phosphatases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction | 1996 |
Chronic ouabain infusion does not cause hypertension in sheep.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Infusions, Intravenous; Ouabain; Potassium; Pulse; Rats; Renin; Renin-Angiotensin System; Sheep; Sodium; Time Factors | 1996 |
Angiotensin II regulation of plasminogen activator inhibitor-1 gene expression in neurons of normotensive and spontaneously hypertensive rat brains.
Topics: Angiotensin II; Animals; Base Sequence; Brain; Cells, Cultured; Gene Expression Regulation; Genes, fos; Hypertension; Molecular Sequence Data; Neurons; Oligonucleotides, Antisense; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Signal Transduction | 1996 |
Angiotensin II causes weight loss and decreases circulating insulin-like growth factor I in rats through a pressor-independent mechanism.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Hematocrit; Hydralazine; Hypertension; Imidazoles; Infusions, Intravenous; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor I; Losartan; Male; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Reference Values; Tetrazoles; Time Factors; Vasodilator Agents; Weight Loss | 1996 |
Plasma angiotensin II, predisposition to hypertension, and left ventricular size in healthy young adults.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Body Weight; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Peptidyl-Dipeptidase A; Regression Analysis; Renin; Renin-Angiotensin System | 1996 |
[Historical perspective of renin-angiotensin system blocking in the treatment of arterial hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Renin-Angiotensin System; Vasoconstrictor Agents | 1996 |
Vascular smooth muscle cells from spontaneously hypertensive rats exhibit increased MAPK response to angiotensin II and phorbol ester stimulation.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Hypertension; Kinetics; Molecular Sequence Data; Muscle, Smooth, Vascular; Myelin Basic Protein; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substrate Specificity; Tetradecanoylphorbol Acetate | 1996 |
Inhibition of hypertension by peripheral administration of antisense oligodeoxynucleotides.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Data Interpretation, Statistical; Drug Carriers; Hypertension; In Vitro Techniques; Liposomes; Liver; Male; Oligonucleotides, Antisense; Protein Biosynthesis; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1996 |
Angiotensin I-converting enzyme genotypes and angiotensin II receptors. Response to therapy.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Base Sequence; Calcium Channel Blockers; Data Interpretation, Statistical; Female; Genetic Markers; Genotype; Humans; Hypertension; Male; Middle Aged; Molecular Sequence Data; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Time Factors | 1996 |
Influence of humoral and neurohormonal factors on cardiovascular hypertrophy in untreated essential hypertensives.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Catecholamines; Echocardiography; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Radioimmunoassay | 1996 |
Cardiac hypertrophy in the Dahl rat is associated with increased tyrosine phosphorylation of several cytosolic proteins, including a 120 kDa protein.
Topics: Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Cytosol; Heart Ventricles; Hypertension; Molecular Weight; Muscle Proteins; Muscle, Skeletal; Myocardium; Phosphorylation; Phosphotyrosine; Precipitin Tests; Rats; Rats, Mutant Strains; Sodium Chloride, Dietary; Tyrosine | 1996 |
Sodium status, corticosteroid metabolism and blood pressure in normal human subjects and in a patient with abnormal salt appetite.
Topics: Adrenal Cortex Hormones; Adult; Aldosterone; Angiotensin II; Appetite; Female; Humans; Hydroxysteroid Dehydrogenases; Hypertension; Male; Middle Aged; Renin; Sodium; Sodium Chloride | 1996 |
A study of angiotensin II receptors after chronic inhibition of nitric oxide synthase in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Enzyme Inhibitors; Female; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Time Factors; Uterus | 1996 |
Influence of forebrain lesions and isoflurane anaesthesia, respectively, on responses to the intracarotid infusion of angiotensin II in sheep.
Topics: Anesthesia; Anesthetics, Inhalation; Angiotensin II; Animals; Blood Pressure; Carotid Arteries; Cerebral Ventricles; Female; Heart; Heart Rate; Hypertension; Infusions, Intra-Arterial; Isoflurane; Prosencephalon; Sheep; Tachycardia; Vasoconstrictor Agents | 1995 |
Different vascular responses to subpressor angiotensin II administration in the mesenteric and renal circulation of rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Hemodynamics; Hypertension; Male; Natriuresis; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Circulation; Splanchnic Circulation; Vascular Resistance | 1996 |
Changes in angiotensin AT1 receptor density during hypertension in fructose-fed rats.
Topics: Angiotensin II; Animals; Blood Pressure; Fructose; Heart Ventricles; Hypertension; Insulin; Male; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin | 1996 |
AT1-receptors and cellular actions of angiotensin II in neuronal cultures of stroke prone-spontaneously hypertensive rat brain.
Topics: Angiotensin II; Animals; Brain; Carrier Proteins; Cells, Cultured; Cerebrovascular Disorders; Hypertension; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Symporters | 1996 |
Chronic infusion of low-dose angiotensin II potentiates the adrenergic response in vivo.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Angiotensin II; Animals; Blood Pressure; Hypertension; Infusion Pumps, Implantable; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstriction; Vasoconstrictor Agents | 1996 |
Blunted renal vascular response to angiotensin II is associated with a common variant of the angiotensinogen gene and obesity.
Topics: Adolescent; Adult; Angiotensin II; Angiotensinogen; Base Sequence; Blood Pressure; Body Mass Index; Female; Genotype; Homozygote; Humans; Hypertension; Infusions, Intravenous; Kidney; Male; Middle Aged; Molecular Sequence Data; Obesity; Oligonucleotide Probes; Pedigree; Renal Artery; Renal Plasma Flow; Vascular Resistance; Vasoconstrictor Agents | 1996 |
Characterization and hemodynamic implications of renal vascular angiotensin II receptors in SHR.
Topics: Angiotensin II; Animals; Hemodynamics; Hypertension; In Vitro Techniques; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Vasomotor System | 1996 |
[Heart hypertrophy. Determinant factors and molecular mechanisms].
Topics: Adult; Age Factors; Aged; Angiotensin II; Cardiomegaly; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Obesity; Racial Groups; Risk Factors; Sex Factors; Thyroid Hormones | 1995 |
[Effect of cilazapril, a converting enzyme inhibitor, on cardiovascular hypertrophy in the hypertensive patient].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Cilazapril; Endothelium, Vascular; Humans; Hypertension; Rats; Renin-Angiotensin System; Vasodilation | 1996 |
Regional haemodynamic effects of antagonists of angiotensin II, endothelin and adrenoceptors in conscious, vasopressin-deficient, genetically hypertensive rats.
Topics: Adrenergic Antagonists; Angiotensin II; Animals; Biphenyl Compounds; Endothelins; Hemodynamics; Hypertension; Imidazoles; Indans; Losartan; Male; Rats; Sodium Chloride; Tetrazoles; Vasopressins | 1996 |
Endogenous opioid mechanisms in hypothalamic blood flow autoregulation during haemorrhagic hypotension and angiotensin-induced acute hypertension in cats.
Topics: Angiotensin II; Animals; Carbon Dioxide; Cats; Central Venous Pressure; Cerebrovascular Circulation; Female; Hemorrhage; Homeostasis; Hypertension; Hypotension; Hypothalamus; Male; Naloxone; Narcotic Antagonists; Receptors, Opioid | 1996 |
Involvement of angiotensin II in glomerulosclerosis of stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blotting, Northern; Cerebrovascular Disorders; Glomerulosclerosis, Focal Segmental; Hypertension; Kidney Glomerulus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; RNA | 1996 |
Low concentrations of angiotensin II unmask vasoconstrictory alpha 2-adrenoceptors in isolated perfused kidneys of spontaneously hypertensive rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Dioxanes; Dose-Response Relationship, Drug; Hypertension; Idazoxan; Imidazoles; Kidney; Methoxamine; Perfusion; Prazosin; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction | 1995 |
Angiotensin II-induced hypertension: effects on central and peripheral atrial natriuretic peptide.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Brain Chemistry; Hypertension; Injections, Intraperitoneal; Injections, Intraventricular; Male; Paraventricular Hypothalamic Nucleus; Preoptic Area; Rats; Rats, Wistar | 1995 |
Chronic blockade of AT2-subtype receptors prevents the effect of angiotensin II on the rat vascular structure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Collagen; Elastin; Fibrosis; Hypertension; Hypertrophy; Imidazoles; Infusions, Parenteral; Losartan; Male; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Wistar; Reference Values; Tetrazoles | 1996 |
The effect of afterload and angiotensin II on proto-oncogene mRNA levels in the isolated working rat heart.
Topics: Angiotensin II; Animals; Blotting, Northern; Cardiomegaly; Female; Gene Expression; Hypertension; Perfusion; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; ras Proteins; Rats; Rats, Wistar; RNA, Messenger | 1996 |
Role of nitric oxide resistance in erythropoietin-induced hypertension in rats with chronic renal failure.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Cyclic GMP; Drug Resistance; Erythropoietin; Hematocrit; Hypertension; Intracellular Membranes; Kidney Failure, Chronic; Male; Nitric Oxide; Nitroprusside; Osmolar Concentration; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilation; Vasodilator Agents | 1996 |
Regulation of ANG II receptor in hypertension: role of ANG II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Gene Expression; Hypertension; Imidazoles; Losartan; Male; Nephrectomy; Ramipril; Rats; Rats, Wistar; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 1996 |
Acute and chronic angiotensin hypertension: neural and nonneural components, time course, and dose dependency.
Topics: Acute Disease; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Chlorisondamine; Chronic Disease; Dose-Response Relationship, Drug; Ganglionic Blockers; Hypertension; Imidazoles; Losartan; Male; Nervous System Physiological Phenomena; Rats; Rats, Sprague-Dawley; Tetrazoles | 1996 |
Physiological significance of plasma sulfoconjugated dopamine in patients with hypertension--clinical and experimental studies.
Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Catechol O-Methyltransferase; Cattle; Dopamine; Female; Humans; Hypertension; Hypertension, Renal; In Vitro Techniques; Liver; Male; Middle Aged; Rats; Reference Values | 1996 |
Losartan reduces cardiac mass and improves coronary flow reserve in the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Coronary Circulation; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 1996 |
Role of protein kinase C in angiotensin II-induced renal vasoconstriction in genetically hypertensive rats.
Topics: Alkaloids; Angiotensin II; Animals; Antihypertensive Agents; Benzophenanthridines; Biphenyl Compounds; Hemodynamics; Hypertension; Imidazoles; Losartan; Phenanthridines; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Staurosporine; Tetrazoles; Vasoconstrictor Agents | 1996 |
Inhibition of the slow pressor effect of angiotensin II contributes to the antihypertensive effect of angiotensin-converting enzyme inhibitors in renovascular hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Rats; Rats, Sprague-Dawley; Urination | 1996 |
Homocysteine induced arteriosclerosis-like alterations of the aorta in normotensive and hypertensive rats following application of high doses of methionine.
Topics: Angiotensin II; Animals; Aorta; Arteriosclerosis; Cholestanols; Cholesterol; Cholic Acid; Cholic Acids; Endothelium, Vascular; Homocysteine; Hypertension; Hypolipidemic Agents; Male; Methionine; Methylthiouracil; Microscopy, Electron; Mitochondria; Rats; Rats, Inbred SHR; Rats, Wistar; Tunica Intima; Vasoconstrictor Agents | 1996 |
Role of ANG II in hypertension produced by chronic inhibition of nitric oxide synthase in conscious rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Enalapril; Hypertension; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reference Values; Tetrazoles; Time Factors | 1996 |
In the Lyon hypertensive rat, renal function alterations are angiotensin II dependent.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Hypertension; Indoles; Kidney; Male; Natriuresis; Perfusion; Perindopril; Pressure; Rats; Rats, Inbred Strains; Receptors, Thromboxane; Reference Values; Renal Circulation; Time Factors; Vasoconstriction | 1996 |
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Azepines; Blood Glucose; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Male; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1996 |
201Tl and 99Tcm-human serum albumin for assessment of the effect of hypertensive treatment with angiotensin II infusion on tumour circulation.
Topics: Angiotensin II; Animals; Female; Humans; Hypertension; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Radionuclide Imaging; Technetium Tc 99m Aggregated Albumin; Thallium Radioisotopes | 1996 |
Induced hypertension during ischemia reduces infarct area after temporary middle cerebral artery occlusion in rats.
Topics: Angiotensin II; Animals; Arterial Occlusive Diseases; Cerebral Arterial Diseases; Cerebral Infarction; Hypertension; Ischemic Attack, Transient; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Chronic control of high blood pressure in the spontaneously hypertensive rat by delivery of angiotensin type 1 receptor antisense.
Topics: Angiotensin II; Animals; Autoradiography; Dose-Response Relationship, Drug; Gene Transfer Techniques; Humans; Hypertension; Oligonucleotides, Antisense; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Zidovudine | 1996 |
Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats.
Topics: 3T3 Cells; Angiotensin II; Animals; Cell Line; Hypertension; Ion Transport; Kidney Tubules, Proximal; Male; Mice; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Sodium | 1996 |
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Clonidine; Diabetes Mellitus, Experimental; Hypertension; Imidazoles; Nifedipine; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin | 1996 |
Angiotensin II related to sodium excretion modulates left ventricular structure in human essential hypertension.
Topics: Adult; Angiotensin II; Cohort Studies; Cross-Sectional Studies; Diet; Echocardiography; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Natriuresis; Sodium | 1996 |
The effect of high dietary n-3 fatty acid supplementation on angiotensin II pressor response in human pregnancy.
Topics: Angiotensin II; Blood Pressure; Dietary Fats; Dose-Response Relationship, Drug; Fatty Acids, Omega-3; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy | 1996 |
[Regular increase in the part of blood flow from the anterior vena cava in total venous return during systemic cardiovascular reactions].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Catecholamines; Cats; Hypertension; Hypoxia; Nitroglycerin; Regional Blood Flow; Vasodilator Agents; Venae Cavae | 1996 |
[Rational hypertension treatment].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Imidazoles; Imidazoline Receptors; Male; Receptors, Drug; Vasodilator Agents | 1996 |
AT1 receptor density changes during development of hypertension in hyperinsulinemic rats.
Topics: Angiotensin II; Animals; Blood Pressure; Fructose; Hyperinsulinism; Hypertension; Insulin; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System | 1996 |
Receptor-mediated intrarenal angiotensin II augmentation in angiotensin II-infused rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Hypertension; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Tetrazoles | 1996 |
Altered calcium homeostasis in tail artery endothelial cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Bradykinin; Calcium; Cells, Cultured; Endothelins; Endothelium, Vascular; Homeostasis; Hypertension; Intracellular Membranes; Male; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tail | 1995 |
Reversal of the suppressed kidney renin level in the hypertensive transgenic rat TGR(mRen-2)27 by angiotensin converting enzyme inhibition.
Topics: Adrenal Glands; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antibodies; Blood Pressure; Hypertension; Indoles; Kidney; Male; Mice; Perindopril; Rats; Renin; Renin-Angiotensin System | 1995 |
Vasodilator effect of human adrenomedullin(13-52) on hypertensive rats.
Topics: Adrenomedullin; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Endothelins; Humans; Hypertension; In Vitro Techniques; Male; Nitric Oxide; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Vasodilator Agents | 1995 |
Blood pressure sensitivity to salt, calcium metabolism and insulin sensitivity in essential hypertension.
Topics: Aged; Angiotensin II; Blood Pressure; Calcium; Dose-Response Relationship, Drug; Humans; Hypertension; Insulin; Middle Aged; Norepinephrine; Salts; Time Factors | 1995 |
Comparison between chronic converting enzyme inhibition and AT1 blockade in mRen2 transgenic rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Isoquinolines; Losartan; Male; Natriuresis; Quinapril; Rats; Tetrahydroisoquinolines; Tetrazoles | 1996 |
Modulation by nitric oxide and prostaglandin of the renal vascular response to angiotensin II (3-8).
Topics: Angiotensin II; Animals; Cyclooxygenase Inhibitors; Drug Interactions; Hypertension; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Vasoconstriction | 1996 |
The inhibitory effect of angiotensin II on stimulus-induced release of cAMP is augmented in the genetically hypertensive rat kidney.
Topics: Angiotensin II; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Hypertension; Isoproterenol; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1996 |
Effect of low dietary calcium intake on blood pressure and pressure natriuresis response in rats: a possible role of the renin-angiotensin system.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Calcium; Calcium, Dietary; Electrolytes; Hypertension; Kidney Function Tests; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 1996 |
Effect of induced hypertension with angiotensin II infusion on biodistribution of 111in-labeled monoclonal antibody.
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Female; Humans; Hypertension; Immunoglobulin G; Indium Radioisotopes; Infusions, Intravenous; Isotope Labeling; Mice; Mice, Inbred BALB C; Rats; Serum Albumin; Technetium; Tissue Distribution; Tumor Cells, Cultured | 1996 |
Vascular reactivity to phenylephrine and angiotensin II in hypertensive rats associated with insulin resistance.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Fructose; Hypertension; Insulin Resistance; Male; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1996 |
Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Crosses, Genetic; Disease Models, Animal; Female; Humans; Hypertension; Kidney Glomerulus; Male; Mice; Mice, Transgenic; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1996 |
Vascular reactivity to angiotensin II in blood-perfused kidneys of hypertensive diabetic rats.
Topics: Angiotensin II; Animals; Diabetes Mellitus, Experimental; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1996 |
Fluid homeostasis after heart transplantation: the role of cardiac denervation.
Topics: Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Denervation; Electrolytes; Female; Heart; Heart Transplantation; Hemodynamics; Hormones; Humans; Hypertension; Liver Transplantation; Male; Middle Aged; Neurosecretory Systems; Plasma Volume; Vasopressins; Ventricular Function, Left | 1996 |
Modulation of target tissue response to angiotensin II and sodium sensitivity in Japanese patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Renin-Angiotensin System; Sodium Chloride | 1996 |
Local renin-angiotensin system in sympathetic overactivity of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Sympathetic Nervous System | 1996 |
Control of renal and mesenteric conductance during hemorrhage in conscious hypertensive rabbits.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Autonomic Nerve Block; Blood Pressure; Female; Hemodynamics; Hemorrhage; Hypertension; Rabbits; Renal Circulation; Splanchnic Circulation | 1996 |
Pharmacodynamic, pharmacokinetic and clinical profile of the first orally active angiotensin II receptor antagonist.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Tetrazoles | 1995 |
Role of the native kidney in experimental post-transplantation hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hybridization, Genetic; Hypertension; Kidney; Kidney Transplantation; Male; Nephrectomy; Radionuclide Imaging; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Technetium Tc 99m Mertiatide; Transplantation, Homologous | 1996 |
Exaggerated tubuloglomerular feedback activity in genetic hypertension is mediated by ANG II and AT1 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Feedback; Hypertension; Imidazoles; Kidney Glomerulus; Kidney Tubules; Loop of Henle; Losartan; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Tetrazoles | 1996 |
Effects of losartan on cerebral arteries in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebral Arteries; Cerebrovascular Disorders; Endothelium, Vascular; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Tetrazoles | 1996 |
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Pressure; Captopril; Epoprostenol; Humans; Hypertension; Peptide Fragments | 1996 |
[Contribution of the renin-angiotensin system to the variability of blood pressure in hypertensive rat after blockade of nitric oxide synthesis].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Heart Rate; Hypertension; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renin-Angiotensin System; Tetrazoles | 1996 |
Brain "ouabain" and angiotensin II in salt-sensitive hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Brain; Guanabenz; Hemodynamics; Hypertension; Imidazoles; Immunoglobulin Fab Fragments; Injections, Intraventricular; Losartan; Male; Ouabain; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles | 1996 |
Angiotensin II induction of osteopontin expression and DNA replication in rat arteries.
Topics: Angiotensin II; Animals; Antimetabolites; Blood Pressure; Bromodeoxyuridine; DNA Replication; Hypertension; In Situ Hybridization; Male; Muscle, Smooth, Vascular; Osteopontin; Rats; Rats, Sprague-Dawley; Sialoglycoproteins | 1996 |
[Angiotensin II antagonists: a distinct therapeutic class].
Topics: Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Tetrazoles | 1996 |
Subpressor doses of angiotensin II do not increase albumin excretion in humans.
Topics: Adult; Albuminuria; Angiotensin II; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Exercise Test; Female; Humans; Hypertension; Male; Renal Circulation | 1996 |
Mouse model for pregnancy problem?
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Crosses, Genetic; Disease Models, Animal; Female; Humans; Hypertension; Male; Mice; Mice, Transgenic; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1996 |
The role of intermediate phenotypes in essential hypertension: non-modulation as a model.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Blood Flow Velocity; Genotype; Humans; Hypertension; Kidney; Middle Aged; Phenotype; Renin; Sodium, Dietary | 1996 |
Alterations of cyclo-oxygenase products and NO in responses to angiotensin II of resistance arteries from the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Cyclooxygenase Inhibitors; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1996 |
Effect of angiotensin II on immunotoxin uptake in tumor and normal tissue.
Topics: Angiotensin II; Animals; Autoradiography; Blood Pressure; Female; Humans; Hypertension; Immunotoxins; Infusions, Parenteral; Injections, Intravenous; Mice; Mice, Nude; Photoplethysmography; Rhabdomyosarcoma; Tissue Distribution; Vasoconstrictor Agents | 1996 |
Changes in angiotensin II receptor density and calcium handling during proliferation in SHR aortic myocytes.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cell Division; Hypertension; Intracellular Membranes; Ionomycin; Male; Muscle, Smooth, Vascular; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Reference Values | 1996 |
[Gradual reduction of arterial pressure and 24-hour blood pressure control as objective of antihypertensive therapy].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Monitoring, Physiologic | 1995 |
Losartan (Cozaar)
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Renin-Angiotensin System; Tetrazoles | 1996 |
[Angiotensin-II receptor blockers].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles | 1996 |
Nitric oxide (NO) modulates the neurogenic control of blood pressure in rats with chronic renal failure (CRF).
Topics: Angiotensin II; Animals; Aorta; Arginine; Blood Pressure; Brain; Creatinine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hypertension; Hypothalamus; Kidney Failure, Chronic; Locus Coeruleus; Male; Medulla Oblongata; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Norepinephrine; Paraventricular Hypothalamic Nucleus; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathetic Nervous System; Synaptic Transmission; Transcription, Genetic | 1997 |
Oxidative stress produced by angiotensin too. Implications for hypertension and vascular injury.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Free Radicals; Humans; Hypertension; Oxidative Stress; Superoxides | 1997 |
Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Blood Vessels; Drug Carriers; Hypertension; Liposomes; Macrophages; Male; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Vasodilation | 1997 |
Endothelial vasoconstrictor prostanoids modulate contractions to acetylcholine and ANG II in Ren-2 rats.
Topics: Acetylcholine; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Body Weight; Endothelin-1; Endothelium, Vascular; Hypertension; Male; Mesenteric Arteries; Mice; Norepinephrine; Potassium Chloride; Prostaglandins; Rats; Rats, Sprague-Dawley; Renin; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Thromboxane is required for full expression of angiotensin hypertension in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Glomerular Filtration Rate; Hypertension; Male; Rats; Rats, Sprague-Dawley; Renin; Thromboxane B2; Thromboxanes | 1997 |
Effects of chronic ETA-receptor blockade in angiotensin II-induced hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hypertension; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Thromboxane A2; Vasoconstrictor Agents | 1997 |
Role of renal nerves in afferent arteriolar reactivity in angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Calcimycin; Denervation; Hypertension; Kidney; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasoconstrictor Agents | 1997 |
Increased brain transcription factor expression by angiotensin in genetic hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Biphenyl Compounds; Blood Pressure; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Hypertension; Imidazoles; Immediate-Early Proteins; Immunohistochemistry; Injections, Intraventricular; Losartan; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Tetrazoles; Transcription Factors | 1997 |
Orthostatic hypertension.
Topics: Angiotensin II; Drug Hypersensitivity; Humans; Hypertension; Norepinephrine; Pressoreceptors | 1997 |
Role of nitric oxide in impaired coronary circulation and improvement by angiotensin II receptor antagonist in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Coronary Circulation; Enzyme Inhibitors; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 1995 |
Mapping of angiotensin II receptor subtypes in peripheral tissues of spontaneously hypertensive rats by in vitro autoradiography.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Biphenyl Compounds; Heart; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; Myocardium; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles | 1995 |
Blockade of AT1 receptors by specific antibody attenuated hypertension development in young spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibody Specificity; Blood Pressure; Body Weight; Hypertension; Immunization; Immunotherapy; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 1996 |
Resistance to mineralocorticoids in Wistar-Furth rats.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Cells, Cultured; Citrate (si)-Synthase; Desoxycorticosterone; Dexamethasone; Hypertension; Muscle, Smooth, Vascular; Potassium; Rats; Rats, Inbred WF; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Sodium, Dietary; Species Specificity; Time Factors; Transcription, Genetic; Up-Regulation | 1997 |
Age, gender, and non-modulation. A sexual dimorphism in essential hypertension.
Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Data Interpretation, Statistical; Female; Genotype; Humans; Hypertension; Infusions, Parenteral; Male; Menopause; Middle Aged; Phenotype; Postmenopause; Premenopause; Sex Factors | 1997 |
Intracellular free calcium abnormalities in fibroblasts from non-insulin-dependent diabetic patients with and without arterial hypertension.
Topics: Aged; Analysis of Variance; Angiotensin II; Biopsy; Bradykinin; Calcium; Cells, Cultured; Diabetes Mellitus, Type 2; Female; Fibroblasts; Humans; Hypertension; Male; Middle Aged; Regression Analysis; Skin | 1997 |
Insulin-induced hypertension in rats depends on an intact renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Glomerular Filtration Rate; Hypertension; Insulin; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Time Factors | 1997 |
Impaired in vivo adrenergic responses in diet-induced hypertensive rats.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Body Weight; Diet; Hypertension; In Vitro Techniques; Insulin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasoconstrictor Agents | 1997 |
Effect of neonatal sympathectomy on development of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Animals, Newborn; Arginine Vasopressin; Blood Pressure; Electric Stimulation; Hypertension; Male; Mesenteric Arteries; Nervous System Physiological Phenomena; Norepinephrine; Rats; Rats, Sprague-Dawley; Sympathectomy; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Role of kinin and renal ANG II blockade in acute effects of ACE inhibitors in low-renin hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Desoxycorticosterone; Dogs; Eicosanoids; Hypertension; Kidney; Kinins; Male; Renin; Sodium Chloride; Thromboxane-A Synthase | 1997 |
Chronic ANG II infusion and reflex control of norepinephrine and corticosterone in conscious rabbits.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Corticosterone; Hypertension; Infusions, Intravenous; Male; Norepinephrine; Rabbits; Reference Values; Time Factors | 1997 |
Hemodynamic characterization of YM435, a novel dopamine DA1 receptor agonist, in anesthetized dogs.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Dogs; Dopamine; Female; Heart Rate; Hemodynamics; Hypertension; Isoquinolines; Male; Norepinephrine; Receptors, Dopamine D1; Renal Circulation; Tetrahydroisoquinolines; Vascular Resistance | 1997 |
Angiotensin receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Scleroderma, Systemic; Tetrazoles | 1997 |
Down-regulation of aortic and cardiac AT1 receptor gene expression in transgenic (mRen-2) 27 rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Base Sequence; Blood Pressure; Cardiomegaly; Down-Regulation; Heart; Hypertension; Mice; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Polymerase Chain Reaction; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Vasoconstrictor Agents | 1997 |
Vascular thrombin receptor regulation in hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Drug Resistance; Hypertension; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Receptors, Thrombin; RNA, Messenger; Sodium Chloride; Superoxides; Systole; Thrombin; Up-Regulation | 1997 |
The response of renal plasma flow to angiotensin II infusion in a population-based sample and its association with the parental history of essential hypertension.
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Infusions, Parenteral; Likelihood Functions; Male; Middle Aged; Phenotype; Renal Plasma Flow; Risk Factors; Sodium, Dietary | 1997 |
Cardiac hypertrophy in diabetic spontaneously hypertensive rats: role of angiotensin II?
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiac Volume; Cardiomegaly; Diabetes Mellitus, Experimental; Heart Septum; Hypertension; Hypertrophy, Left Ventricular; Male; Organ Size; Rats; Rats, Inbred SHR | 1997 |
Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Apoptosis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Fragmentation; Gene Expression; Heart Failure; Hypertension; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger | 1997 |
Effects of enalapril, losartan, and verapamil on blood pressure and glucose metabolism in the Cohen-Rosenthal diabetic hypertensive rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Disease Models, Animal; Enalapril; Glucose; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred Strains; Tetrazoles; Verapamil | 1997 |
Baroreflex control of heart rate and cardiac hypertrophy in angiotensin II-induced hypertension in rabbits.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Infusion Pumps; Rabbits | 1997 |
Effect of angiotensin II on the reactivity of isolated mesenteric vessels to norepinephrine in rats poisoned with cadmium.
Topics: Analysis of Variance; Angiotensin II; Animals; Cadmium; Hypertension; Male; Mesenteric Artery, Superior; Norepinephrine; Rats; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Glomerular hyperfiltration during sympathetic nervous system activation in early essential hypertension.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Birth Weight; Blood Pressure; Cilazapril; Glomerular Filtration Rate; Hormones; Humans; Hypertension; Male; Renal Circulation; Stress, Psychological; Sympathetic Nervous System | 1997 |
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 1st communication: antihypertensive effects of valsartan in hypertensive models.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Dogs; Enalapril; Heart Rate; Hypertension; Hypertension, Renal; Male; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Tetrazoles; Valine; Valsartan | 1997 |
Endothelial dysfunction in spontaneously hypertensive rats: consequences of chronic treatment with losartan or captopril.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Captopril; Endothelium, Vascular; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Superoxide Dismutase; Tetrazoles; Vasoconstriction; Vasodilation | 1997 |
Elevated albumin excretion in nonmodulating essential hypertensive patients.
Topics: Adult; Albuminuria; Angiotensin II; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Drug Resistance; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Phenotype; Renin; Risk Factors; Sodium, Dietary | 1997 |
24-hour recordings of blood pressure, heart rate and behavioural activity in rabbits by radio-telemetry: effects of feeding and hypertension.
Topics: Angiotensin II; Animals; Arousal; Blood Pressure Monitors; Circadian Rhythm; Diastole; Electrocardiography; Equipment Design; Feeding Behavior; Female; Heart Rate; Hypertension; Male; Motor Activity; Psychophysiology; Rabbits; Systole; Telemetry | 1997 |
Role of the renal kallikrein-kinin system in the development of hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Bradykinin; Disease Models, Animal; Hypertension; Infusions, Intra-Arterial; Injections, Subcutaneous; Kallikrein-Kinin System; Kidney Tubules; Kininogens; Lactones; Molecular Weight; Norepinephrine; Rats; Rats, Inbred BN; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium Chloride; Sodium, Dietary | 1997 |
Role for endothelin-1 in angiotensin II-mediated hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Dioxoles; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Serotonin; Staining and Labeling; Tetrazoles; Time Factors; Vasoconstrictor Agents | 1997 |
Induction of mitogen-activated protein kinase phosphatase-1 during acute hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; Cardiovascular System; Cells, Cultured; Data Interpretation, Statistical; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hypertension; Male; Mitogens; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Phosphoprotein Phosphatases; Protein Kinases; Protein Phosphatase 1; Rats; Rats, Wistar; Restraint, Physical; RNA; Stress, Physiological; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 1997 |
Humoral factor(s) produced by pressure overload enhance cardiac hypertrophy and natriuretic peptide expression.
Topics: Angiotensin II; Animals; Aortic Coarctation; Atrial Natriuretic Factor; Atrophy; Blood Pressure; Body Weight; Cardiomegaly; Endothelin-1; Heart Rate; Heart Transplantation; Hypertension; Male; Myosins; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Rats; Rats, Inbred Lew; RNA, Messenger; Transcription, Genetic; Transplantation, Heterotopic; Transplantation, Isogeneic | 1997 |
Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biphenyl Compounds; Captopril; Cells, Cultured; Hypertension; Hypertrophy; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nifedipine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 1997 |
Renal effects of an angiotensin II antagonist in stroke-prone spontaneously hypertensive rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Body Weight; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Imidazoles; Kidney; Kidney Function Tests; Kidney Glomerulus; Losartan; Organ Size; Proteinuria; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles; Tissue Embedding | 1997 |
Relationship between some humoral factors and left ventricular hypertrophy in essential hypertension.
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Parathyroid Hormone; Renin-Angiotensin System | 1996 |
Proximal tubular fluid, kidney, and plasma levels of angiotensin II in hypertensive ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Body Fluids; Genes; Hypertension; Kidney; Kidney Tubules, Proximal; Male; Rats; Rats, Sprague-Dawley; Renin | 1997 |
Elevated blood pressure in spontaneously hypertensive rats consuming a high sucrose diet is associated with elevated angiotensin II and is reversed by vanadium.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Dietary Sucrose; Endothelin-1; Hypertension; Male; Radioimmunoassay; Rats; Rats, Inbred SHR; Vanadium | 1997 |
Relationship between blood pressure and renin, angiotensin II and atrial natriuretic factor after renal transplantation.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Radioimmunoassay; Regression Analysis; Renin; Sodium | 1997 |
Autonomy of the renin system in type II diabetes mellitus: dietary sodium and renal hemodynamic responses to ACE inhibition.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 2; Diet, Sodium-Restricted; Enalapril; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Renal Circulation; Renin; Renin-Angiotensin System | 1997 |
Fibrosis of atria and great vessels in response to angiotensin II or aldosterone infusion.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Autoradiography; Binding Sites; Endomyocardial Fibrosis; Fibrosis; Heart Atria; Hypertension; Male; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Vasoconstrictor Agents | 1997 |
Angiotensin II responses of vascular smooth muscle cells from hypertensive rats: enhancement at the level of p42 and p44 mitogen activated protein kinase.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Genistein; Hypertension; In Vitro Techniques; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents | 1997 |
Renal neurogenic mediation of intracerebroventricular angiotensin II hypertension in rats raised on high sodium chloride diet.
Topics: Angiotensin II; Animals; Animals, Newborn; Denervation; Diet; Dose-Response Relationship, Drug; Hypertension; Injections, Intraventricular; Kidney; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1997 |
Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cardiomegaly; Collagen; Diastole; Heart; Hydroxyproline; Hypertension; Mice; Myocardial Contraction; Myocardium; Myosin Heavy Chains; Rats; Renin; RNA, Messenger; Sarcoplasmic Reticulum; Systole | 1997 |
Nitric oxide synthase and renin-angiotensin system gene expression in salt-sensitive and salt-resistant Sabra rats.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Drug Resistance; Endothelium, Vascular; Enzyme Induction; Gene Expression; Hypertension; Immunohistochemistry; Kidney; Male; Nervous System; Nitric Oxide Synthase; Rats; Rats, Mutant Strains; Reference Values; Renin-Angiotensin System; Sodium Chloride | 1997 |
Role of angiotensin II in activation of the JAK/STAT pathway induced by acute pressure overload in the rat heart.
Topics: Acute Disease; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Enhancer Elements, Genetic; Enzyme Activation; Hypertension; Janus Kinase 2; Myocardium; Phosphoproteins; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Rats; Rats, Wistar; Trans-Activators; TYK2 Kinase | 1997 |
Short-period-induced hypertension could improve tumor-to-nontumor ratios of radiolabeled monoclonal antibody.
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Female; Hypertension; Indium Radioisotopes; Mice; Mice, Inbred BALB C; Mice, Nude; Radioimmunodetection; Tissue Distribution | 1997 |
Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihypertensive Agents; Body Weight; Cardiomegaly; Cardiovascular System; Hypertension; Hypertrophy; Indoles; Kidney; Losartan; Male; Mesenteric Arteries; Organ Size; Papaverine; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vascular Resistance | 1997 |
Angiotensin receptor antagonism and angiotensin converting enzyme inhibition improve diastolic dysfunction and Ca(2+)-ATPase expression in the sarcoplasmic reticulum in hypertensive cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blotting, Northern; Blotting, Western; Calcium-Transporting ATPases; Captopril; Cardiomyopathy, Hypertrophic; Diastole; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Mice; Mice, Transgenic; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sarcoplasmic Reticulum; Tetrazoles | 1997 |
Exaggerated natriuresis in transgenic (mRen2)27 rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Hypertension; Kidney Cortex; Kidney Function Tests; Kidney Medulla; Laser-Doppler Flowmetry; Male; Natriuresis; Rats; Rats, Inbred Strains; Renal Circulation; Renin; Sodium; Sympathetic Nervous System | 1997 |
Potentiation of the hypotensive effect of bradykinin by short-term infusion of angiotensin-(1-7) in normotensive and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Drug Synergism; Hypertension; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar | 1997 |
Angiotensin II-induced hypertension increases heme oxygenase-1 expression in rat aorta.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Antioxidants; Aorta; Biphenyl Compounds; Blood Pressure; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hypertension; Imidazoles; Losartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Systole; Tetrazoles; Vasoconstrictor Agents | 1997 |
[Angiotensin II antagonists].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Tetrazoles; Water-Electrolyte Balance | 1995 |
Long-term blockade of the angiotensin II receptor in renin transgenic rats, salt-loaded Dahl rats, and stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Atrial Natriuretic Factor; Body Weight; Cerebrovascular Disorders; Cyclic GMP; Dihydropyridines; Hemodynamics; Hormones; Hypertension; Kidney; Rats; Rats, Inbred SHR; Renin; Tetrazoles | 1997 |
Actions of angiotensin and lisinopril on thalamic somatosensory neurons in normotensive, non-transgenic and hypertensive, transgenic rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Disease Models, Animal; Electroencephalography; Hypertension; Imidazoles; Lisinopril; Losartan; Male; Neurons, Afferent; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thalamus; Vasoconstrictor Agents | 1997 |
Arterial function in mineralocorticoid-NaCl hypertension: influence of angiotensin-converting enzyme inhibition.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Isoquinolines; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Quinapril; Rats; Rats, Inbred WKY; Sodium Chloride; Tetrahydroisoquinolines | 1997 |
Antihypertensive activity of a nonpeptide angiotensin II receptor antagonist, YM358, in rats and dogs.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Azoles; Biphenyl Compounds; Blood Pressure; Dogs; Female; Heart Rate; Hypertension; Hypertension, Renal; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Renin-Angiotensin System; Sodium | 1997 |
Pivotal role of the renin-angiotensin system in Lyon hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiac Output; Enzyme Precursors; Heart Rate; Hemodynamics; Hypertension; Indoles; Kidney Cortex; Male; Perindopril; Rats; Rats, Inbred Strains; Regional Blood Flow; Renin; Renin-Angiotensin System; Vascular Resistance | 1997 |
[Treatment of hypertension with angiotensin blockers].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diuretics; Humans; Hypertension | 1997 |
Pharmacokinetic-pharmacodynamic relations of losartan and EXP3174 in a porcine animal model.
Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Area Under Curve; Blood Pressure; Disease Models, Animal; Half-Life; Hypertension; Imidazoles; Infusions, Intravenous; Losartan; Receptors, Angiotensin; Swine; Tetrazoles | 1997 |
Pharmacologic profiles of KRH-594, a novel nonpeptide angiotensin II-receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Cattle; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Liver; Losartan; Male; Rabbits; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles; Thiadiazoles | 1997 |
Angiotensin II mediates cell hypertrophy in vascular smooth muscle cultures from hypertensive Ren-2 transgenic rats by an amiloride- and furosemide-sensitive mechanism.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biological Transport; Cell Size; Cells, Cultured; Femoral Artery; Furosemide; Heterozygote; Hypertension; Hypertrophy; Male; Mice; Muscle, Smooth, Vascular; Ouabain; Rats; Rats, Sprague-Dawley; Renin; Rubidium | 1997 |
Monocyte chemoattractant protein-1 expression in aortic tissues of hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Chemokine CCL2; Hydralazine; Hypertension; Infusions, Parenteral; Macrophages; Male; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Mechanical; Transcription, Genetic | 1997 |
Role of angiotensin II in the regulation of a novel vascular modulator, hepatocyte growth factor (HGF), in experimental hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Enalapril; Gene Expression Regulation, Developmental; Heart; Hepatocyte Growth Factor; Humans; Hypertension; Imidazoles; Losartan; Lung; Male; Myocardium; Organ Specificity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regression Analysis | 1997 |
AT1 receptor antagonist treatment caused persistent arterial functional changes in young spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Electric Stimulation; Heart; Hypertension; Imidazoles; Kidney; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1997 |
Bosentan prevents preglomerular alterations during angiotensin II hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Endothelin-1; Hypertension; Kidney Glomerulus; Male; Microscopy, Video; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides; Systole | 1997 |
[Bosentan attenuates the hypertensive effect of angiotensin II in rats].
Topics: Angiotensin II; Animals; Blood Pressure; Bosentan; Disease Models, Animal; Drug Interactions; Endothelin Receptor Antagonists; Endothelins; Hemodynamics; Hypertension; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Sulfonamides | 1997 |
G protein-coupled receptor kinase 5 in cultured vascular smooth muscle cells and rat aorta. Regulation by angiotensin II and hypertension.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; G-Protein-Coupled Receptor Kinase 5; Hemodynamics; Hypertension; Muscle, Smooth, Vascular; Norepinephrine; Protein Serine-Threonine Kinases; Rats; Receptor Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Up-Regulation | 1997 |
The plasma membrane Ca(2+)-ATPase in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cells, Cultured; Hypertension; Isoenzymes; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Transcription, Genetic | 1997 |
Role of angiotensin II and bradykinin on aortic collagen following converting enzyme inhibition in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Bradykinin; Bradykinin Receptor Antagonists; Collagen; Drug Therapy, Combination; Hemodynamics; Hypertension; Hypertrophy; Imidazoles; Isoquinolines; Male; Quinapril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Tetrahydroisoquinolines; Tetrazoles | 1997 |
Polymorphism of angiotensin converting enzyme gene is associated with circulating levels of plasminogen activator inhibitor-1.
Topics: Alleles; Angiotensin II; Asian People; Comorbidity; Coronary Disease; Diabetes Mellitus; Ethnicity; Female; Genetic Variation; Genotype; Humans; Hypercholesterolemia; Hypertension; Korea; Male; Mass Screening; Middle Aged; Obesity; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Postmenopause; Risk Factors; Sequence Deletion; Sex Characteristics; Smoking | 1997 |
Role of calcium influx and intracellular calcium stores in angiotensin II-mediated calcium hyper-responsiveness in smooth muscle from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Extracellular Space; Hypertension; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 1997 |
Tumor necrosis factor-alpha-angiotensin interactions and regulation of blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Dinoprostone; Drug Interactions; Hypertension; Immune Sera; In Vitro Techniques; Kidney Medulla; Loop of Henle; Male; Rats; Rats, Sprague-Dawley; Reference Values; Tumor Necrosis Factor-alpha | 1997 |
Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator balance of RAS.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Aorta, Thoracic; Blood Pressure; Estradiol; Estrogen Replacement Therapy; Female; Hypertension; Kidney; Mice; Models, Cardiovascular; Muscle, Smooth, Vascular; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 1997 |
Systemic hemodynamic responses to chronic angiotensin II infusion into the renal artery of dogs.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Dogs; Ganglia, Autonomic; Glomerular Filtration Rate; Hemodynamics; Hypertension; Infusions, Intra-Arterial; Kidney; Male; Regional Blood Flow; Renal Artery; Renal Circulation; Time Factors; Vascular Resistance | 1997 |
[Angiotensin II-receptor antagonists. New targets in the management of hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Humans; Hypertension | 1997 |
Losartan and renal transplantation.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Erythrocyte Count; Erythropoiesis; Humans; Hypertension; Kidney Transplantation; Losartan; Male; Postoperative Complications | 1998 |
Transgenic hypertensive rats show a reduced angiotensin II induced [Ca2+]i response in glomerular mesangial cells.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Calcium; Cytosol; Dose-Response Relationship, Drug; Glomerular Mesangium; Hypertension; Male; Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Vasoconstrictor Agents | 1998 |
[Value of angiotensin II-antagonists in kidney diseases and hypertension. Symposium on the occasion of the 102nd Session of the German Society of Internal Medicine, Wiesbaden, 14 April 1996].
Topics: Angiotensin II; Antihypertensive Agents; Humans; Hypertension; Hypertension, Renal; Kidney Diseases; Vasodilator Agents | 1996 |
Myriad's lifestyle test targets borderline hypertensives.
Topics: Angiotensin II; Blood Pressure; Contraindications; Genotype; Humans; Hypertension; Life Style; Pharmacogenetics; Risk Factors; Sodium, Dietary | 1998 |
Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Bosentan; Endothelin Receptor Antagonists; Heart; Hemodynamics; Hypertension; Kidney; Male; Organ Size; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides | 1998 |
Downregulation of angiotensin II type 1 receptor gene transcription by nitric oxide.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cells, Cultured; Cyclic GMP; Down-Regulation; Hypertension; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Fusion Proteins; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Transcription, Genetic; Transfection | 1998 |
AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cerebrovascular Disorders; Cyclic GMP; Hypertension; Imidazoles; Losartan; Male; Minoxidil; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values | 1998 |
Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dipeptides; Heart Rate; Hypertension; Kinetics; Lisinopril; Losartan; Male; Neprilysin; Organophosphonates; Peptide Fragments; Peptides, Cyclic; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 1998 |
Renal nerves promote sodium excretion in angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Creatinine; Denervation; Dogs; Female; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Hypertension; Infusions, Intravenous; Kidney; Potassium; Renal Circulation; Sodium; Sympathetic Nervous System; Urinary Bladder | 1998 |
Maintenance of baseline angiotensin II potentiates insulin hypertension in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Drug Synergism; Glucose; Hypertension; Insulin; Kidney; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Thromboxane B2; Vascular Resistance | 1998 |
Abnormal regulation of transforming growth factor-beta receptors on vascular smooth muscle cells from spontaneously hypertensive rats by angiotensin II.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta | 1998 |
Evidence for persistent dysfunction of wild-type aldosterone synthase gene in glucocorticoid-treated familial hyperaldosteronism type I.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blotting, Southern; Cytochrome P-450 CYP11B2; Dexamethasone; Female; Follow-Up Studies; Gene Expression Regulation, Enzymologic; Glucocorticoids; Humans; Hyperaldosteronism; Hypertension; Infusions, Intravenous; Male; Middle Aged; Polymerase Chain Reaction; Potassium; Prednisolone; Renin; Vasoconstrictor Agents | 1997 |
[Physiopathology of angiotensin II and vascular lesion].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Humans; Hypertension; Losartan | 1997 |
Effects of angiotensin II type 1 receptor blockade and angiotensin-converting enzyme inhibition on cardiac beta-adrenergic signal transduction.
Topics: Adenylyl Cyclases; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Atrial Natriuretic Factor; Blood Pressure; GTP-Binding Proteins; Heart; Hypertension; Myocardium; Neuropeptide Y; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, beta; Signal Transduction | 1998 |
Prostaglandin I2 contributes to the vasodepressor effect of baicalein in hypertensive rats.
Topics: Angiotensin II; Animals; Arachidonate 12-Lipoxygenase; Blood Pressure; Enzyme Inhibitors; Epoprostenol; Flavanones; Flavonoids; Hypertension; Lipoxygenase Inhibitors; Male; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 1998 |
Actions of des-Asp angiotensin I on the aortic rings of the normo- and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Aorta; Drug Evaluation, Preclinical; Hypertension; In Vitro Techniques; Logistic Models; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1998 |
Activation of glomerular mitogen-activated protein kinases in angiotensin II-mediated hypertension.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Hypertension; Infusions, Intravenous; JNK Mitogen-Activated Protein Kinases; Kidney Glomerulus; Male; Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Sp1 Transcription Factor; Time Factors; Transcription Factor AP-1; Vasoconstrictor Agents | 1998 |
Acute hypertension promotes hemorrhagic transformation in a rabbit embolic stroke model: effect of labetalol.
Topics: Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Cerebral Hemorrhage; Cerebral Infarction; Hypertension; Intracranial Embolism and Thrombosis; Labetalol; Male; Rabbits | 1998 |
Characterization of angiotensin-(1-7) in the urine of normal and essential hypertensive subjects.
Topics: Adult; Age Factors; Angiotensin I; Angiotensin II; Cross-Sectional Studies; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Peptide Fragments | 1998 |
Species variability in angiotensin receptor expression by cultured cardiac fibroblasts and the infarcted heart.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arachidonic Acid; Calcium; Cell Membrane; Cells, Cultured; Collagen; Fibroblasts; Hypertension; Myocardial Infarction; Myocardium; Rabbits; Radioligand Assay; Rats; Receptors, Angiotensin; Species Specificity; Time Factors | 1998 |
Effect of neonatal sympathectomy on the development of structural vascular changes in angiotensin II-treated rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Hypertension; Hypertrophy; Male; Mesenteric Arteries; Rats; Rats, Sprague-Dawley; Sympathectomy; Sympathetic Nervous System | 1998 |
An early prenatal exposure to excess glucocorticoid leads to hypertensive offspring in sheep.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Dexamethasone; Dose-Response Relationship, Drug; Female; Gestational Age; Glucocorticoids; Hydrocortisone; Hypertension; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Sheep | 1998 |
The arterial length-densities under preventive angiotensin-converting-enzyme inhibiting treatment in the myocardium of spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Capillaries; Coronary Vessels; Dose-Response Relationship, Drug; Hypertension; Myocardium; Neovascularization, Pathologic; Organ Size; Ramipril; Random Allocation; Rats; Rats, Inbred SHR; Vasoconstrictor Agents | 1998 |
[Treatment of hypertension. Angiotensin blockade: an established therapeutic principle].
Topics: Angiotensin II; Humans; Hypertension | 1998 |
Increased mRNA expression of cardiac renin-angiotensin system and collagen synthesis in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Collagen; Hypertension; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger | 1998 |
Endogenous angiotensin II and cell hypertrophy in vascular smooth muscle cultures from hypertensive Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cell Division; Cell Size; Cells, Cultured; Disease Models, Animal; Femoral Artery; Gene Expression Regulation; Genes, fos; Genes, jun; Hypertension; Hypertrophy; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Renin; Tunica Media | 1998 |
Mesangiolytic glomerulopathy in severe congestive heart failure.
Topics: Adult; Aged; Angiotensin II; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Capillaries; Female; Glomerulonephritis, Membranoproliferative; Heart Failure; Hematocrit; Humans; Hypertension; Kidney Glomerulus; Macrophages; Male; Middle Aged; Oxygen; Periodic Acid-Schiff Reaction | 1998 |
Tissue angiotensin II concentration in the heart and kidneys in transgenic Tsukuba hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Sclerosis | 1998 |
Angiotensin converting enzyme inhibition modulates cardiac fibroblast growth.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Division; Cells, Cultured; Culture Media; Endomyocardial Fibrosis; Estradiol; Estrone; Female; Fibroblasts; Gene Expression; Genes, fos; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular; Isoquinolines; Male; Menopause; Myocardium; Rats; Sp1 Transcription Factor; Tetrahydroisoquinolines | 1998 |
[Role of angiotensin II as blood pressure regulator and the the development of lesions in hypertension target organs].
Topics: Angiotensin II; Blood Pressure; Cardiovascular System; Humans; Hypertension | 1998 |
Tubuloglomerular feedback and prolonged ACE-inhibitor treatment in the hypertensive fawn-hooded rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Feedback; Hypertension; Kidney Glomerulus; Kidney Tubules; Male; Rats | 1998 |
Opposite associations of circulating aldosterone and atrial natriuretic peptide with left ventricular diastolic function in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Coronary Circulation; Diastole; Echocardiography; Female; Humans; Hypertension; Male; Middle Aged; Ventricular Function, Left | 1998 |
Guanine nucleotide-binding inhibitory protein-mediated inhibition of adenylyl cyclase is enhanced in spontaneously hypertensive rat preglomerular arteriolar smooth muscle cells.
Topics: Adenylyl Cyclase Inhibitors; Angiotensin II; Animals; Arterioles; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1998 |
[The relationship between insulin resistance and angiotensin II and endothelins in patients with essential hypertension and coronary heart disease].
Topics: Adult; Aged; Angiotensin II; Blood Glucose; Coronary Disease; Endothelins; Female; Humans; Hypertension; Insulin; Insulin Resistance; Male; Middle Aged | 1996 |
Endothelin-1 expression in hearts of transgenic hypertensive mice overexpressing angiotensin II.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Progression; Endothelin Receptor Antagonists; Endothelin-1; Hemodynamics; Humans; Hypertension; Indans; Male; Mice; Mice, Transgenic; Myocardium; Polymerase Chain Reaction; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger | 1998 |
Effects of balloon angioplasty and stent implantation on intrarenal echo-Doppler velocimetric indices.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Laser-Doppler Flowmetry; Male; Middle Aged; Regression Analysis; Renal Artery Obstruction; Renal Circulation; Renin; Stents | 1998 |
Pressure overload induces cardiac hypertrophy in angiotensin II type 1A receptor knockout mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cardiomegaly; Echocardiography; Hypertension; Mice; Mice, Knockout; Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Transcription, Genetic | 1998 |
Myosin isoform shifts and decreased reactivity in hypoxia-induced hypertensive pulmonary arterial muscle.
Topics: Adenosine; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension; Hypoxia; Male; Muscle, Smooth, Vascular; Myosins; Norepinephrine; Potassium; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Serotonin | 1998 |
Renoprotective effects of nitric oxide in angiotensin II-induced hypertension in the rat.
Topics: Angiotensin II; Animals; Enzyme Inhibitors; Hypertension; Kidney; Laser-Doppler Flowmetry; Male; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Renal Circulation | 1998 |
Interactive nitric oxide-angiotensin II influences on renal microcirculation in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Arterioles; Data Interpretation, Statistical; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Penicillamine; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Losartan but not verapamil inhibits angiotensin II-induced tissue endothelin-1 increase: role of blood pressure and endothelial function.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Data Interpretation, Statistical; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hypertension; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred WKY; Receptors, Endothelin; Time Factors; Vasoconstriction; Vasodilation; Vasodilator Agents; Verapamil | 1998 |
Reduction of cold-induced hypertension by antisense oligodeoxynucleotides to angiotensinogen mRNA and AT1-receptor mRNA in brain and blood.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antisense Elements (Genetics); Aorta; Autoradiography; Blood; Blood Pressure; Brain; Cold Temperature; Drinking; Hypertension; Kidney; Male; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Time Factors | 1998 |
Vascular expression of heat shock protein 72 in fructose-induced hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Fructose; Heat-Shock Proteins; Hot Temperature; HSP72 Heat-Shock Proteins; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Sprague-Dawley; Shock | 1998 |
Early administration of angiotensin-converting enzyme inhibitor captopril, prevents the development of hypertension programmed by intrauterine exposure to a maternal low-protein diet in the rat.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Captopril; Diet, Protein-Restricted; Female; Humans; Hypertension; Infant, Newborn; Male; Pregnancy; Rats; Rats, Wistar | 1998 |
Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Dietary Fats, Unsaturated; gamma-Linolenic Acid; Hypertension; Male; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin | 1998 |
Effects of the AT1 antagonist HR 720 in comparison to losartan on stimulated sympathetic outflow, blood pressure, and heart rate in pithed spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Catecholamines; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hemodynamics; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Sympathetic Nervous System | 1998 |
Increased functional Na(+)-K+ pump activity in the vasculature of fructose-fed hyperinsulinemic and hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Arteries; Blood Glucose; Blood Pressure; Body Weight; Dietary Carbohydrates; Dose-Response Relationship, Drug; Electric Stimulation; Femoral Artery; Fructose; Humans; Hyperinsulinism; Hypertension; In Vitro Techniques; Insulin; Male; Muscle Relaxation; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Tail; Vasoconstrictor Agents | 1998 |
Dietary-sodium-induced cardiac remodeling in spontaneously hypertensive rat versus Wistar-Kyoto rat.
Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Ganglionic Blockers; Heart Rate; Heart Ventricles; Hexamethonium; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Organ Size; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium, Dietary; Sympathetic Nervous System | 1998 |
Renal AT1 receptor: autoradiographic localization and quantification in rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Kidney; Kidney Cortex; Male; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1998 |
Renal AT1 receptor: computerized quantification in spontaneously hypertensive rats and DOCA-salt rats.
Topics: Age Factors; Angiotensin II; Animals; Autoradiography; Blood Pressure; Desoxycorticosterone; Heart Rate; Hypertension; Image Processing, Computer-Assisted; Kidney Cortex; Kidney Medulla; Male; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Sodium Chloride | 1998 |
Production of eicosanoids and angiotensin II in resistance vessels in spontaneously hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Body Weight; Dinoprostone; Eicosanoids; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1998 |
Professor Alberto C. Taquini 1905-1998.
Topics: Angiotensin II; Argentina; Cardiology; History, 20th Century; Hypertension; Research | 1998 |
Evaluation of the renin-angiotensin system in a congenic renin Dahl salt-sensitive rat.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Enzyme Inhibitors; Hypertension; Kidney; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; RNA, Messenger; Saralasin; Sodium | 1997 |
Hypothalamic angiotensin receptor subtypes in normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Binding, Competitive; Hypertension; Hypothalamus; Imidazoles; Kinetics; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Species Specificity | 1998 |
Heparin inhibits mesenteric vascular hypertrophy in angiotensin II-infusion hypertension in rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Fibrinolytic Agents; Heparin; Hypertension; Hypertrophy; Male; Mesenteric Veins; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Vasoconstrictor Agents | 1998 |
Quantitative receptor radioautography in the study of receptor-receptor interactions in the nucleus tractus solitarii.
Topics: Angiotensin II; Animals; Autoradiography; Blood Pressure; Clonidine; Epinephrine; Hypertension; Neuropeptide Y; Norepinephrine; Rats; Receptors, Adrenergic; Receptors, Angiotensin; Receptors, Neuropeptide Y; Solitary Nucleus | 1998 |
Angiotensin II mediates systemic rebound hypertension after cessation of prostacyclin infusion in sheep.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Catecholamines; Epoprostenol; Hemodynamics; Hypertension; Phentolamine; Prostaglandin Antagonists; Renin; Renin-Angiotensin System; Sheep; Sympathetic Nervous System | 1998 |
Angiotensin II receptor antagonists: what future?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Enalapril; Humans; Hypertension; Losartan | 1998 |
Microvasculature in angiotensin II-dependent cardiac hypertrophy in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arterioles; Capillaries; Hypertension; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Vasoconstrictor Agents | 1998 |
Mechanisms of spontaneous baroreflex impairment in lyon hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Heart Rate; Hypertension; Indoles; Losartan; Male; Perindopril; Rats | 1998 |
Angiotensinogen genotype and blood pressure responses to reduced dietary NaCl and to weight loss.
Topics: Adult; Angiotensin II; Animals; Blood Pressure; Diet, Sodium-Restricted; Genotype; Humans; Hypertension; Sodium Chloride, Dietary; Weight Loss | 1998 |
Effects of angiotensin II and losartan in the forearm of patients with essential hypertension.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Enzyme Inhibitors; Female; Forearm; Humans; Hypertension; Losartan; Male; Methoxamine; Middle Aged; omega-N-Methylarginine; Regional Blood Flow; Vasoconstrictor Agents | 1998 |
[Effect of chronic bradykinin infusion on angiotensin II hypertension in rats].
Topics: Angiotensin II; Animals; Bradykinin; Disease Models, Animal; Hypertension; Hypertrophy, Left Ventricular; Male; Rats; Rats, Sprague-Dawley | 1998 |
Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Dose-Response Relationship, Drug; Enzyme Activation; Heart Ventricles; Hypertension; Infusions, Intra-Arterial; Infusions, Intravenous; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley | 1998 |
Salt-sensitive aortic aneurysm and rupture in hypertensive transgenic mice that overproduce angiotensin II.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Rupture; Drug Resistance; Female; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Sodium Chloride | 1998 |
AT1 receptors mediate chronic central nervous system AII hypertension in rats fed high sodium chloride diet from weaning.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Central Nervous System Diseases; Chronic Disease; Diet, Sodium-Restricted; Hypertension; Injections, Intraventricular; Losartan; Natriuresis; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Weaning | 1998 |
Modulation by angiotensin II of isoproterenol-induced cAMP production in preglomerular microvascular smooth muscle cells from normotensive and genetically hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Calmodulin; Cyclic AMP; GTP-Binding Proteins; Hypertension; Isoproterenol; Kidney Glomerulus; Male; Microcirculation; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1998 |
The effect of renin-angiotensin system inhibitors on pro- and anti-inflammatory cytokine production.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cytokines; Humans; Hypertension; Interleukin-1; Interleukin-6; Lipopolysaccharides; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 1998 |
Structural vascular changes in hypertension: role of angiotensin II, dietary sodium supplementation, blood pressure, and time.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Hypertension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Splanchnic Circulation; Time Factors | 1998 |
Metabolites of the angiotensin II antagonist tasosartan: the importance of a second acidic group.
Topics: Administration, Oral; Adrenal Glands; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Heart Rate; Hypertension; In Vitro Techniques; Injections, Intravenous; Liver; Models, Molecular; Molecular Conformation; Pyridones; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Structure-Activity Relationship; Tetrazoles | 1998 |
Central and peripheral mechanisms involved in hypertension induced by chronic inhibition of nitric oxide synthase in rats.
Topics: Acute Disease; Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chronic Disease; Denervation; Enzyme Inhibitors; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phentolamine; Rats; Rats, Wistar; Sinoatrial Node; Tetrazoles | 1998 |
Roles of brain angiotensin II and C-type natriuretic peptide in deoxycorticosterone acetate-salt hypertension in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Desoxycorticosterone; Hypertension; Infusions, Parenteral; Injections, Intravenous; Injections, Intraventricular; Male; Natriuretic Peptide, C-Type; Rats; Rats, Wistar; Sodium Chloride; Tetrazoles | 1998 |
Regulation of vascular type 1 angiotensin II receptor in hypertension and sodium loading: role of angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium, Dietary | 1998 |
Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Autoradiography; Blotting, Northern; Colforsin; Desoxycorticosterone; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hypertension; Immunoblotting; Isoproterenol; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcolemma; Sodium Chloride; Time Factors | 1998 |
Angiotensin hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Hypertension; Renin-Angiotensin System; Time Factors | 1998 |
Parathyroid hormone-related protein expression in vascular smooth muscle of spontaneously hypertensive rats: evidence for lack of response to angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blotting, Northern; Hemodynamics; Hypertension; Injections, Intravenous; Male; Muscle, Smooth, Vascular; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Proto-Oncogene Proteins c-myc; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Vasoconstrictor Agents | 1998 |
Increased pressor function of central vasopressinergic system in hypertensive renin transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Cerebral Ventricles; Cerebrospinal Fluid; Hormone Antagonists; Hypertension; Losartan; Male; Rats; Rats, Sprague-Dawley; Renin; Vasopressins | 1998 |
[Effects of angiotensin II receptors antagonist losartan on metabolism and morphofunctional condition myocardium in hypertensive patients].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Echocardiography; Follow-Up Studies; Heart Ventricles; Humans; Hypertension; Losartan; Male; Middle Aged; Myocardial Contraction; Myocardium; Renin | 1998 |
Diminished salt appetite in spontaneously hypertensive rats following local administration of the angiotensin II antagonist saralasin in the median preoptic area.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Appetite; Drinking; Hypertension; Injections; Male; Preoptic Area; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Saralasin; Sodium, Dietary | 1997 |
Altered muscle metabolism associated with vasoconstriction in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Glucose; Hypertension; Lactic Acid; Male; Muscle, Skeletal; Norepinephrine; Oxygen Consumption; Prazosin; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Activation of neuropeptide FF neurons in the brainstem nucleus tractus solitarius following cardiovascular challenge and opiate withdrawal.
Topics: Angiotensin II; Animals; Hemodynamics; Hypertension; Hypotension; Male; Morphine; Morphine Dependence; Naloxone; Neurons; Nitroprusside; Oligopeptides; Phenylephrine; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Solitary Nucleus; Substance Withdrawal Syndrome | 1998 |
Both brain angiotensin II and "ouabain" contribute to sympathoexcitation and hypertension in Dahl S rats on high salt intake.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Body Weight; Brain; Cardiotonic Agents; Guanabenz; Hemodynamics; Hypertension; Nitroprusside; Ouabain; Phenylephrine; Rats; Rats, Inbred Dahl; Sodium Chloride; Stress, Physiological | 1998 |
Dopamine D1 receptor and protein kinase C isoforms in spontaneously hypertensive rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Angiotensin II; Animals; Biological Transport; Fenoldopam; Hypertension; Isoenzymes; Kidney Tubules; Norepinephrine; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Dopamine D1; Sodium-Potassium-Exchanging ATPase | 1998 |
Enhanced angiotensin II stimulates renal disorders in transgenic Tsukuba hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Gene Expression; Humans; Hypertension; Kidney Diseases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Renin-Angiotensin System | 1998 |
Effect of chronic captopril treatment on circulating and tissue renin-angiotensin system in SHR rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Hypertension; Hypertrophy, Left Ventricular; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger | 1996 |
[The changes of intraerythrocyte calcium metabolism and their responses to nifedipine in patients with essential hypertension].
Topics: Adenosine Triphosphatases; Angiotensin II; Biological Transport, Active; Calcium; Calcium Channel Blockers; Delayed-Action Preparations; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Renin-Angiotensin System | 1997 |
Role of angiotensin II in hyperinsulinemia-induced hypertension in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Chronic Disease; Fosinopril; Hyperinsulinism; Hypertension; Insulin; Kidney; Losartan; Male; Rats; Rats, Sprague-Dawley | 1998 |
Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Carbazoles; Carvedilol; Heart Function Tests; Hydralazine; Hypertension; Isoquinolines; Losartan; Norepinephrine; Propanolamines; Quinapril; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrahydroisoquinolines | 1998 |
Involvement of angiotensin II in development of spontaneous nephrosis in Dahl salt-sensitive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Body Weight; Calcium Channel Blockers; Cholesterol; Glucocorticoids; Hypertension; Imidazoles; Imidazolidines; Losartan; Male; Methylprednisolone; Nephrosis; Proteinuria; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Verapamil | 1998 |
Adrenal, kidney, and heart angiotensins in female murine Ren-2 transfected hypertensive rats.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensins; Animals; Animals, Genetically Modified; Chromatography, High Pressure Liquid; Estrus; Female; Hemodynamics; Hypertension; Kidney; Mice; Myocardium; Rats; Rats, Sprague-Dawley; Renin; Transgenes | 1998 |
Tissue-localized angiotensin II enhances cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Humans; Hydralazine; Hypertension; Kidney Diseases; Lisinopril; Mice; Mice, Inbred C57BL; Mice, Transgenic; Renin | 1998 |
Candesartan cilexetil protects against loss of autoregulatory efficiency in angiotensin II-infused rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Homeostasis; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstriction | 1999 |
Effects of candesartan on angiotensin II-induced renal vasoconstriction in rats and mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Hypertension; Kidney; Mice; Mice, Knockout; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Regional Blood Flow; Renal Artery; Tetrazoles; Time Factors; Vasoconstriction | 1999 |
Blood flow rate in normal and tumor-bearing rats in conscious state, under urethane anesthesia, and during systemic hypothermia.
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Angiotensin II; Animals; Cardiac Output; Ceftazidime; Cephalosporins; Consciousness; Fever; Hemodynamics; Hydrogen; Hypertension; Hypothermia, Induced; Laser-Doppler Flowmetry; Male; Microspheres; Models, Biological; Neoplasms, Experimental; Rats; Rats, Wistar; Regional Blood Flow; Urethane | 1998 |
Role of NO and angiotensin II in the early development of endothelial functions impairment and cardiac hypertrophy in deoxycorticosterone acetate-salt hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cardiomegaly; Desoxycorticosterone; Endothelium, Vascular; Hypertension; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Rats; Rats, Sprague-Dawley; Sodium Chloride; Splanchnic Circulation | 1998 |
Rearrangement of the ventricular capillary network in stroke-prone spontaneously hypertensive rats (SHRSP) following a late start of treatment with the angiotensin converting enzyme blocker temocapril.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Capillaries; Coronary Vessels; Heart Rate; Heart Ventricles; Hypertension; Male; Rats; Rats, Inbred SHR; Thiazepines | 1998 |
Differential regulation of renal angiotensin subtype AT1A and AT2 receptor protein in rats with angiotensin-dependent hypertension.
Topics: Acute Disease; Angiotensin I; Angiotensin II; Animals; Blotting, Western; Down-Regulation; Female; Gene Expression Regulation; Hypertension; Hypertension, Renal; Immunohistochemistry; Kidney; Kidney Glomerulus; Kidney Tubules; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1999 |
Regulation of angiotensin II type 1 receptor mRNA and protein in angiotensin II-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Gene Expression Regulation; Hypertension; Infusions, Intravenous; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1999 |
Roles of AT1 and AT2 receptors in the hypertensive Ren-2 gene transgenic rat kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Blood Pressure; Heart Rate; Hemodynamics; Homozygote; Hypertension; Imidazoles; Kidney; Kidney Tubules; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Renal Circulation; Renin | 1999 |
Angiotensin II type 1 receptor antisense gene therapy prevents altered renal vascular calcium homeostasis in hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Calcium; Cells, Cultured; DNA, Antisense; Genetic Therapy; Homeostasis; Hypertension; Male; Membrane Potentials; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Vascular Resistance; Vasoconstriction | 1999 |
Role of AT2 receptors in angiotensin II-stimulated contraction of small mesenteric arteries in young SHR.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction | 1999 |
Increased central angiotensin and osmotic responses in the Ren-2 transgenic rat.
Topics: Analysis of Variance; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cerebral Ventricles; Heart Rate; Heterozygote; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Vasopressins | 1999 |
Local renal medullary L-NAME infusion enhances the effect of long-term angiotensin II treatment.
Topics: Angiotensin II; Animals; Blood Pressure; Drug Synergism; Hypertension; Infusions, Intravenous; Infusions, Parenteral; Kidney Cortex; Kidney Medulla; Nephrectomy; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Time Factors | 1999 |
Neuronal nitric oxide synthase-dependent afferent arteriolar function in angiotensin II-induced hypertension.
Topics: Acetazolamide; Angiotensin II; Animals; Arterioles; Blood Pressure; Citrulline; Enzyme Inhibitors; Hypertension; Juxtaglomerular Apparatus; Kidney Medulla; Male; Microscopy, Video; Muscle, Smooth, Vascular; Nephrons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Rats; Rats, Sprague-Dawley; Thiourea; Vasoconstriction; Vasodilation | 1999 |
Failure of platelet angiotensin II binding to predict pregnancy-induced hypertension.
Topics: Adolescent; Adult; Angiotensin II; Biomarkers; Blood Platelets; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Sensitivity and Specificity | 1999 |
Angiotensin I converting enzyme and angiotensinogen gene polymorphisms related to 24-h blood pressure in paediatric type I diabetes mellitus.
Topics: Adolescent; Angiotensin II; Blood Pressure; Child; Diabetes Mellitus, Type 1; Female; Gene Frequency; Genotype; Humans; Hypertension; Male; Peptidyl-Dipeptidase A; Polymorphism, Genetic | 1999 |
Hypertrophic response to hemodynamic overload: role of load vs. renin-angiotensin system activation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cats; Constriction, Pathologic; Elasticity; Heart; Hemodynamics; Hypertension; Hypertrophy, Right Ventricular; Losartan; Myocardial Contraction; Myocardium; Pulmonary Artery; Renin-Angiotensin System | 1999 |
Exaggerated Ca2+ signaling in preglomerular arteriolar smooth muscle cells of genetically hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Arterioles; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cytosol; Hypertension; In Vitro Techniques; Kidney Glomerulus; Male; Muscle, Smooth, Vascular; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1999 |
Effects of the new angiotensin II type 1 receptor antagonist KRH-594 on several types of experimental hypertension.
Topics: Administration, Oral; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Callithrix; Dogs; Female; Heart Rate; Hypertension; Kidney Function Tests; Male; Mice; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Species Specificity; Tetrazoles; Thiadiazoles | 1999 |
Angiotensin II increases the release of endothelin-1 from human cultured endothelial cells but does not regulate its circulating levels.
Topics: Adult; Angiotensin II; Cell Culture Techniques; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Receptors, Angiotensin | 1999 |
Which drug for treatment of hypertension?
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Follow-Up Studies; Humans; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 1999 |
Differential kinetics of circulating angiotensin IV and II after treatment with angiotensin II type 1 receptor antagonist and their plasma levels in patients with chronic renal failure.
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Rats; Rats, Wistar; Renal Dialysis; Tetrazoles | 1999 |
Angiotensin II AT1-receptor blockade inhibits monocyte activation and adherence in transgenic (mRen2)27 rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Cell Count; Blood Pressure; Cell Adhesion; Endothelium, Vascular; Female; Heart Rate; Hematocrit; Hydralazine; Hypertension; Losartan; Male; Monocytes; Nitroblue Tetrazolium; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 1999 |
In vivo pharmacologic profile of SK-1080, an orally active nonpeptide AT1-receptor antagonist.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Consciousness; Diastole; Diuretics; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Furosemide; Heart Rate; Hypertension; Hypertension, Renal; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1999 |
Sympathetic nervous system activity and alpha-adrenergic responsiveness in older hypertensive humans.
Topics: Adenylyl Cyclases; Aged; Aging; Angiotensin II; Blood Platelets; Epinephrine; Female; Forearm; GTP-Binding Proteins; Humans; Hypertension; Kinetics; Male; Middle Aged; Norepinephrine; Receptors, Adrenergic, alpha; Regional Blood Flow; Sympathetic Nervous System | 1999 |
Renin-angiotensin system stimulates cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Humans; Hydralazine; Hypertension; Kidney Diseases; Lisinopril; Mice; Mice, Inbred C57BL; Renin; Renin-Angiotensin System; Survival Rate | 1999 |
Mitogen-activated protein/extracellular signal-regulated kinase inhibition attenuates angiotensin II-mediated signaling and contraction in spontaneously hypertensive rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Hydrogen-Ion Concentration; Hypertension; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents | 1999 |
Chronic bradykinin infusion and receptor blockade in angiotensin II hypertension in rats.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Disease Models, Animal; Hemodynamics; Hypertension; Kidney; Male; Organ Size; Potassium; Rats; Rats, Sprague-Dawley | 1999 |
Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Hypertension; Neurons; Neurotransmitter Agents; Norepinephrine; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction | 1999 |
Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Arginine Vasopressin; Blood Pressure; Brain; Cerebral Ventricles; Diabetes Insipidus; Electrolytes; Exons; Hypertension; Hypotension; Injections, Intraventricular; Organ Specificity; Rats; Renin; RNA, Antisense; RNA, Messenger; Transcription, Genetic | 1999 |
[Relations between blood insulin concentration, renin-angiotensin-aldosterone system and clinical picture of hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Biomarkers; Blood Glucose; Blood Pressure; Echocardiography; Glucose Tolerance Test; Heart Ventricles; Humans; Hypertension; Insulin; Male; Myocardial Contraction; Renin; Renin-Angiotensin System; Severity of Illness Index | 1999 |
Historical evolution of angiotensin II receptor blockers: therapeutic advantages.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiovascular Diseases; History, 19th Century; History, 20th Century; Humans; Hypertension; Renin-Angiotensin System | 1999 |
Salt-sensitive hypertension develops after short-term exposure to Angiotensin II.
Topics: Angiotensin II; Animals; Hypertension; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1999 |
A novel immunoscintigraphy technique using metabolizable linker with angiotensin II treatment.
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Humans; Hypertension; Immunoglobulin Fab Fragments; Ligands; Mice; Mice, Nude; Osteosarcoma; Radioimmunodetection; Tissue Distribution; Tumor Cells, Cultured | 1999 |
[The "Dieter Klaus Price for Hypertension Research 199". Central angiotensin II is important for blood pressure regulation].
Topics: Angiotensin II; Awards and Prizes; Blood Pressure; Humans; Hypertension; Renin-Angiotensin System | 1999 |
[Drug clinics. Drug of the month. Irbesartan (Aprovel)].
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Dose-Response Relationship, Drug; Half-Life; Humans; Hypertension; Irbesartan; Rabbits; Tetrazoles; Vasodilator Agents | 1999 |
Differential response of angiotensin peptides in the urine of hypertensive animals.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Body Weight; Drinking; Electrolytes; Hemodynamics; Hypertension; Lisinopril; Losartan; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley | 1999 |
Alpha-adrenergic systems mediate chronic central AII hypertension in rats fed high sodium chloride diet from weaning.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brain; Chronic Disease; Diet; Hypertension; Injections, Intraventricular; Natriuresis; Phentolamine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sodium Chloride; Weaning | 1999 |
Production of angiotensin II by homogeneous cultures of vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Benzimidazoles; Biphenyl Compounds; Cathepsin D; Cathepsin E; Cell Division; Cells, Cultured; Culture Media, Conditioned; Hyperplasia; Hypertension; Hypertrophy; Indans; Kallikreins; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Tissue Kallikreins | 1999 |
11beta-hydroxysteroid dehydrogenase in cultured human vascular cells. Possible role in the development of hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Angiotensin II; Base Sequence; Cells, Cultured; Chromatography, Thin Layer; Coronary Vessels; Corticosterone; DNA Primers; Gene Expression; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Hypertension; Molecular Sequence Data; Muscle Tonus; Muscle, Smooth, Vascular; Receptors, Angiotensin; RNA, Messenger | 1999 |
Paracrine role of adventitial superoxide anion in mediating spontaneous tone of the isolated rat aorta in angiotensin II-induced hypertension.
Topics: Acridines; Angiotensin II; Animals; Anions; Aorta, Thoracic; Calcium; Data Interpretation, Statistical; Enzyme Inhibitors; Hypertension; Immunohistochemistry; In Vitro Techniques; Luminescent Measurements; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; NADPH Oxidases; Nifedipine; Nitric Oxide; Onium Compounds; Paracrine Communication; Rats; Rats, Wistar; Superoxide Dismutase; Superoxides; Vasodilator Agents | 1999 |
Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Enzyme Precursors; Female; Follow-Up Studies; Gene Expression; Heart Rate; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Treatment Outcome | 1999 |
An effort to understand the molecular basis of hypertension through the study of conformational analysis of losartan and sarmesin using a combination of nuclear magnetic resonance spectroscopy and theoretical calculations.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Hypertension; Losartan; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Monte Carlo Method; Protein Conformation | 1999 |
Endothelial dysfunction in the aorta of transgenic rats harboring the mouse Ren-2 gene.
Topics: Acetylcholine; Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Blood Pressure; Body Weight; Endothelin-1; Endothelins; Endothelium, Vascular; Hypertension; Male; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Protein Precursors; Rats; Rats, Sprague-Dawley; Renin | 1999 |
The effects of short-term nifedipine treatment on responsiveness of aortic rings of cadmium-hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cadmium Chloride; Calcium Channel Blockers; Disease Models, Animal; Endothelin-1; Follow-Up Studies; Hypertension; Male; Nifedipine; Norepinephrine; Random Allocation; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Inhibitory effect of antisense basic fibroblast growth factor oligonucleotides on proliferation of cultured aortic smooth muscle cells induced by angiotensin II in SHR rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; Fibroblast Growth Factor 2; Gene Expression; Hypertension; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Rats; Rats, Inbred SHR; RNA, Messenger | 1998 |
Proliferation of aortic smooth muscle cells and renin-angiotensin system in SHR rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Hypertension; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Saralasin | 1998 |
Vascular mitogen-activated protein kinase activity is enhanced via angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Hypertension; Losartan; Male; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1999 |
Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cells, Cultured; Extracellular Space; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Norepinephrine; Organ Culture Techniques; Superoxide Dismutase; Systole; Vasoconstrictor Agents | 1999 |
The A1166C mutation in the angiotensin II type I receptor and hypertension in the elderly.
Topics: Angiotensin II; Case-Control Studies; Female; Genotype; Humans; Hypertension; Male; Middle Aged; Mutation; Polymorphism, Restriction Fragment Length; Prospective Studies; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1999 |
Effect of steroid hormones on blood pressure.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Blood Pressure; Dexamethasone; Female; Glucocorticoids; Hypertension; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Sheep; Vasoconstrictor Agents | 1999 |
Brain renin-angiotensin system and ouabain-induced sympathetic hyperactivity and hypertension in Wistar rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arteries; Baroreflex; Brain; Guanabenz; Heart; Hypertension; Injections, Intraventricular; Kidney; Lung; Male; Nervous System Diseases; Ouabain; Rats; Rats, Wistar; Renin-Angiotensin System; Stress, Physiological; Sympathetic Nervous System | 1999 |
Preactivated peripheral blood monocytes in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Cells, Cultured; Cytokines; Female; Humans; Hypertension; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Middle Aged; Monocytes; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 1999 |
Contribution of extracellular signal-regulated kinase to angiotensin II-induced transforming growth factor-beta1 expression in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hypertension; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Transcription Factor AP-1; Transforming Growth Factor beta | 1999 |
Torasemide inhibits angiotensin II-induced vasoconstriction and intracellular calcium increase in the aorta of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biphenyl Compounds; Calcium; Cells, Cultured; Endothelium, Vascular; Furosemide; Hypertension; Intracellular Membranes; Irbesartan; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Sulfonamides; Tetrazoles; Torsemide; Vasoconstriction | 1999 |
Intrarenal angiotensin converting enzyme inhibition in spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dose-Response Relationship, Drug; Enalapril; Heart Rate; Hypertension; Infusion Pumps; Kidney; Kidney Medulla; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Species Specificity | 1999 |
Altered angiotensin II-induced small artery contraction during the development of hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Follow-Up Studies; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasopressins | 1999 |
Increased renal vasodilator prostanoids prevent hypertension in mice lacking the angiotensin subtype-2 receptor.
Topics: Angiotensin II; Animals; Cyclic AMP; Diet, Sodium-Restricted; Dinoprostone; Epoprostenol; Female; Hypertension; Indomethacin; Kidney; Male; Mice; Mice, Inbred C57BL; Receptors, Angiotensin; Vasodilation | 1999 |
Increased bradykinin and "normal" angiotensin peptide levels in diabetic Sprague-Dawley and transgenic (mRen-2)27 rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Glucose; Body Weight; Bradykinin; Diabetes Mellitus, Experimental; Enzymes; Female; Hormones; Hypertension; Kidney; Mice; Organ Size; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reference Values; Renin | 1999 |
Induced hypertension treatment to improve cerebral ischemic injury after transient forebrain ischemia.
Topics: Adenosine Triphosphate; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Brain Edema; Cerebrovascular Circulation; Energy Metabolism; Gerbillinae; Hypertension; Ischemic Attack, Transient; Male; Phenylephrine; Phosphocreatine; Prosencephalon; Reperfusion Injury; Survival Rate | 1999 |
Effects of chronic oral treatment with imidapril and TCV-116 on the responsiveness to angiotensin II in ventrolateral medulla of SHR.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Hypertension; Imidazoles; Imidazolidines; Male; Medulla Oblongata; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents | 1999 |
Hypertension: drug therapy options for older patients.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Humans; Hypertension; Life Style | 1999 |
Inhibitory effects of captopril on c-myc expression during left ventricular hypertrophy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Genes, myc; Hypertension; Hypertrophy, Left Ventricular; Male; Proto-Oncogene Proteins c-myc; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger | 1998 |
ANG II-induced Ca(2+) increase in smooth muscle cells from SHR is regulated by actin and microtubule networks.
Topics: Actins; Angiotensin II; Animals; Calcium; Cells, Cultured; Enzyme Inhibitors; Hypertension; Male; Microtubules; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thapsigargin | 1999 |
Effects of a lipoxygenase inhibitor, panaxynol, on vascular contraction induced by angiotensin II.
Topics: Alkynes; Angiotensin II; Animals; Blood Pressure; Cricetinae; Disease Models, Animal; Diynes; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Fatty Alcohols; Hypertension; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Vasoconstriction | 1999 |
2nd International Symposium on Angiotensin II Antagonism. London, United Kingdom, 15-18 February 1999. Abstracts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Humans; Hypertension | 1999 |
[The study of mutation in exon 17 of insulin receptor gene in essential hypertensive pedigrees].
Topics: Adolescent; Angiotensin II; Blood Glucose; Exons; Female; Humans; Hypertension; Insulin; Insulin Resistance; Male; Middle Aged; Point Mutation; Receptor, Insulin | 1997 |
The influence of angiotensin II on sex-dependent proliferation of aortic VSMC isolated from SHR.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cell Division; Cells, Cultured; Female; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Sex Characteristics; Systole | 1998 |
Cytosolic free calcium response to angiotensin II in aortic VSMC isolated from male and female SHR.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cell Separation; Cytosol; Dose-Response Relationship, Drug; Female; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Sex Characteristics | 1998 |
Early onset salt-sensitive hypertension in bradykinin B(2) receptor null mice.
Topics: Age Factors; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Blotting, Northern; Body Weight; Data Interpretation, Statistical; Female; Hypertension; Kallikrein-Kinin System; Kidney; Male; Mice; Mice, Knockout; Pregnancy; Radioimmunoassay; Receptors, Angiotensin; Receptors, Bradykinin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 1999 |
Activation of the brain angiotensin system by in vivo human angiotensin-converting enzyme gene transfer in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Base Sequence; Blood Pressure; Brain; Data Interpretation, Statistical; Gene Transfer Techniques; Heart Rate; Humans; Hypertension; Male; Molecular Sequence Data; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transfection; Transgenes | 1999 |
Renin activity and blood pressure in response to chronic episodic hypoxia.
Topics: Adrenal Medulla; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Chemoreceptor Cells; Chromatography, High Pressure Liquid; Chronic Disease; Circadian Rhythm; Data Interpretation, Statistical; Denervation; Hemodynamics; Hypertension; Hypoxia; Kidney; Losartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recurrence; Renal Artery; Renin; Renin-Angiotensin System; Sleep Apnea Syndromes; Sympathetic Nervous System; Time Factors | 1999 |
Hyper-responsiveness to angiotensin II is related to cardiac structural adaptation in hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Hypersensitivity; Echocardiography; Follow-Up Studies; Glomerular Filtration Rate; Heart Ventricles; Humans; Hypertension; Injections, Intravenous; Male; Predictive Value of Tests; Radioimmunoassay; Renal Circulation; Vasoconstrictor Agents | 1999 |
Contribution of synthetic phenotype on the enhanced angiotensin II-generating system in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Cells, Cultured; Hypertension; Male; Muscle, Smooth, Vascular; Phenotype; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger | 1999 |
Salt-sensitive hypertension in ANP knockout mice is prevented by AT1 receptor antagonist losartan.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Hypertension; Losartan; Mice; Mice, Knockout; Sodium Chloride, Dietary | 1999 |
Angiotensin II induces vascular cell adhesion molecule-1 expression in rat vasculature: A potential link between the renin-angiotensin system and atherosclerosis.
Topics: Angiotensin II; Animals; Arteriosclerosis; Blood Pressure; Cells, Cultured; Gene Expression; Hypertension; Immunohistochemistry; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Vascular Cell Adhesion Molecule-1 | 1999 |
[Cellular adhesion to elements of the extracellular matrix in the hypertensive rat modulates the effect of angiotensin II].
Topics: Angiotensin II; Animals; Calcium; Cell Adhesion; Cells, Cultured; Collagen; Cytosol; Extracellular Matrix; Fibronectins; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Vitronectin | 1999 |
Sudden pressure elevation can trigger acute muscle cell death of the heart and aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Apoptosis; Blood Pressure; Cell Survival; Cells, Cultured; Disease Models, Animal; Drug Interactions; Hypertension; In Situ Nick-End Labeling; Injections, Intravenous; Male; Muscle, Smooth, Vascular; Myocardium; Necrosis; Rabbits; Reference Values; Statistics, Nonparametric; Viper Venoms | 1999 |
Low-renin and nonmodulating essential hypertension.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin; Sodium Channels; Vasoconstrictor Agents | 1999 |
Activation of the Na(+)-H+ exchanger modulates angiotensin II-stimulated Na(+)-dependent Mg2+ transport in vascular smooth muscle cells in genetic hypertension.
Topics: Amiloride; Angiotensin II; Animals; Cells, Cultured; Hydrogen-Ion Concentration; Hypertension; Ion Transport; Magnesium; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 1999 |
Low-dose angiotensin II reduces urinary cyclic AMP excretion in spontaneously hypertensive, but not normotensive, rats: independence from hypertension and renal hemodynamic effects of angiotensin.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cyclic AMP; Female; Hemodynamics; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1999 |
Angiotensin II-induced renal vasoconstriction in genetic hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Catecholamines; Drug Interactions; Hypertension; Kidney; Pertussis Toxin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Vascular Resistance; Vasoconstriction; Virulence Factors, Bordetella | 1999 |
Sustained inhibition of angiotensin I-converting enzyme (ACE) expression and long-term antihypertensive action by virally mediated delivery of ACE antisense cDNA.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; DNA, Complementary; Endothelium, Vascular; Genetic Vectors; Hypertension; Oligonucleotides, Antisense; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Retroviridae; Virion | 1999 |
Altered sodium perception in essential hypertensive patients following rapid volume expansion.
Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dextrans; Female; Humans; Hypertension; Infusions, Intravenous; Male; Plasma Substitutes; Prospective Studies; Renal Circulation; Renin; Renin-Angiotensin System; Sodium Chloride; Sodium, Dietary; Vasoconstrictor Agents | 1999 |
Angiotensin II stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Cells, Cultured; Endothelium, Vascular; Female; Gene Expression Regulation; Humans; Hypertension; Intercellular Adhesion Molecule-1; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Umbilical Veins | 1999 |
Proteoglycan production by vascular smooth muscle cells from resistance arteries of hypertensive rats.
Topics: Angiotensin II; Animals; Becaplermin; Cells, Cultured; Hypertension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proteoglycans; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred SHR; Rats, Wistar; Vascular Resistance; Vasoconstrictor Agents | 1999 |
Cardiovascular effects of angiotensin-(1-7) in conscious spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Drug Interactions; Hypertension; Infusions, Intravenous; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1999 |
Delayed recovery of hypertension after single dose losartan in angiotensin II-infused conscious rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Interactions; Hypertension; Infusions, Intravenous; Losartan; Male; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstrictor Agents | 1999 |
Arterial function in nitric oxide-deficient hypertension: influence of long-term angiotensin II receptor antagonism.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cromakalim; Cyclooxygenase Inhibitors; Diclofenac; Hypertension; In Vitro Techniques; Isoproterenol; Losartan; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Vasodilator Agents | 1999 |
[On angiotensin II receptor antagonists in the treatment of hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Receptors, Angiotensin | 1999 |
Relation between the renin-angiotensin-aldosterone system and left ventricular structure and function in young normotensive and mildly hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Echocardiography; Heart Ventricles; Humans; Hypertension; Male; Myocardial Contraction; Radioimmunoassay; Renin; Renin-Angiotensin System; Sodium; Sodium, Dietary; Ultrasonography, Doppler, Pulsed; Ventricular Function; Ventricular Function, Left | 1999 |
[Genetic analysis of candidate gene polymorphisms in elderly hypertension].
Topics: Aged; Angiotensin II; Angiotensinogen; Apolipoproteins; Case-Control Studies; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Risk Factors | 1999 |
AT(1) receptor regulation in salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Brain; Diet, Sodium-Restricted; Drug Resistance; Hypertension; Kidney; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; RNA, Messenger; Sodium Chloride; Vasoconstrictor Agents | 1999 |
Brain "ouabain" and angiotensin II contribute to cardiac dysfunction after myocardial infarction.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Volume; Brain; Cardenolides; Glycosides; Heart; Hemodynamics; Hyperemia; Hypertension; In Vitro Techniques; Male; Myocardial Infarction; Rats; Rats, Wistar | 1999 |
Increased activity and expression of Ca(2+)-dependent NOS in renal cortex of ANG II-infused hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Hypertension; Kidney Cortex; Kidney Medulla; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reference Values | 1999 |
Angiotensin II induces insulin resistance independent of changes in interstitial insulin.
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Dogs; Extracellular Space; Femoral Artery; Glucose; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Inulin; Lymph; Male; Regional Blood Flow; Vascular Resistance; Vasoconstrictor Agents | 1999 |
Plasma concentrations of angiotensin metabolites in young male normotensive and mild hypertensive subjects.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Humans; Hypertension; Male | 1999 |
Evaluation of noninvasive blood pressure recording by photoplethysmography in clinical studies using angiotensin challenges.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure Determination; Clinical Trials, Phase I as Topic; Computers; Data Collection; Dose-Response Relationship, Drug; Humans; Hypertension; Photoplethysmography; Regression Analysis; Reproducibility of Results; Time Factors | 1999 |
Cardiovascular responses to angiotensins I and II in normotensive and hypertensive rats; effects of NO synthase inhibition or ET receptor antagonism.
Topics: Angiotensin I; Angiotensin II; Animals; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hemodynamics; Hypertension; Indans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Vasoconstrictor Agents | 1999 |
Increased leukotriene A(4) hydrolase expression in the heart of angiotensin II-induced hypertensive rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blotting, Northern; Blotting, Western; Epoxide Hydrolases; Fibroblasts; Hemodynamics; Hydralazine; Hypertension; Imidazoles; Immunohistochemistry; Leukocytes; Myocardium; Prodrugs; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors; Up-Regulation; Vasodilator Agents | 1999 |
[Clinical characteristics and follow-up of patients attending a hospital hypertension clinic. 10-year experience].
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Data Interpretation, Statistical; Diabetes Complications; Diuretics; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Obesity; Outpatients; Risk Factors; Time Factors | 1999 |
Differential effects of losartan and doxazosin on vascular function in senescent spontaneously hypertensive rats.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Doxazosin; Endothelium, Vascular; Hypertension; Losartan; Male; Nitrates; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasodilation; Vasodilator Agents | 1999 |
Specific direct radioimmunoassay of angiotensin II (AT II) in human plasma and the effect of angiotensin converting enzyme (ACE) inhibitor.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Pregnancy; Pregnancy Complications, Cardiovascular; Radioimmunoassay | 1999 |
Calcium-mediated mechanisms of eicosapentaenoic acid-induced relaxation in hypertensive rat aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium; Cells, Cultured; Eicosapentaenoic Acid; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Hypertension; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Potassium Channels; Rats; Rats, Inbred SHR; Vasoconstrictor Agents; Vasodilation | 1999 |
The effects of angiotensin II, endothelin-1, and protein kinase C inhibitor on DNA synthesis and intracellular calcium mobilization in vascular smooth muscle cells from young normotensive and spontaneously hypertensive rats.
Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Calcium; Cells, Cultured; DNA; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Hypertension; Intracellular Fluid; Muscle, Smooth, Vascular; Phenanthridines; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spectrometry, Fluorescence; Thymidine; Vasoconstriction | 1999 |
Extracellular signal-regulated kinase pathway is involved in basic fibroblast growth factor effect on angiotensin II-induced Ca(2+) transient in vascular smooth muscle cell from Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Cell Size; DNA; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Hypertension; In Vitro Techniques; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Biosynthesis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thapsigargin | 2000 |
NF-kappaB inhibition ameliorates angiotensin II-induced inflammatory damage in rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; Chemokine CCL2; Coronary Circulation; Coronary Disease; DNA; Gene Expression; Humans; Hypertension; Intercellular Adhesion Molecule-1; Kidney Diseases; Male; NF-kappa B; Nitric Oxide Synthase; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1; Vasculitis | 2000 |
Angiotensin II type 1 receptor blockade prevents cardiac remodeling in bradykinin B(2) receptor knockout mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Female; Fibrosis; Heart Failure; Heart Rate; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Knockout; Myocardium; Nicotinic Acids; Organ Size; Phenotype; Pregnancy; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, Bradykinin; Tetrazoles | 2000 |
Elevated sympathetic activity contributes to hypertension and salt sensitivity in diabetic obese Zucker rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Carotid Arteries; Circadian Rhythm; Diabetes Mellitus; Diabetes Mellitus, Type 2; Ganglionic Blockers; Heart Rate; Hexamethonium; Hypertension; Losartan; Male; Obesity; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Vasoconstriction | 2000 |
Renin-angiotensin system genetic polymorphisms and salt sensitivity in essential hypertension.
Topics: Adult; Alleles; Angiotensin II; Angiotensinogen; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Gene Deletion; Gene Frequency; Genotype; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2000 |
Effect of hypertension on the angiotensin II fibres arriving at the posterior lobe of the hypophysis of the rat. An immunohistochemical study.
Topics: Angiotensin II; Animals; Antibodies; Hypertension; Immunohistochemistry; Male; Mice; Nerve Fibers; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2000 |
Nitric oxide affects angiotensin II pressor response: possible mechanism of attenuated pressor response during pregnancy and etiology of pregnancy-induced hypertension.
Topics: Angiotensin II; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Female; Hypertension; Injections, Intraperitoneal; Nitric Oxide; omega-N-Methylarginine; Pregnancy; Pregnancy Complications, Cardiovascular; Pressoreceptors; Probability; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Software; Vasoconstrictor Agents | 2000 |
The effect of treatment with low dose ACE inhibitor and/or diuretic on coronary microvasculature in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Blood Pressure; Capillaries; Coronary Vessels; Diuretics; Drug Synergism; Heart; Hypertension; Indapamide; Male; Myocardium; Perindopril; Rats; Rats, Inbred SHR | 2000 |
Effect of angiotensin II on liposome uptake by the rat brain in vivo.
Topics: Angiotensin II; Animals; Area Under Curve; Blood-Brain Barrier; Brain; Disease Models, Animal; Drug Carriers; Hypertension; Liposomes; Rats | 1999 |
The effect of propofol on angiotensin II-induced Ca(2+) mobilization in aortic smooth muscle cells from normotensive and hypertensive rats.
Topics: Anesthetics, Intravenous; Angiotensin II; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Hypertension; Male; Muscle, Smooth, Vascular; Propofol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thapsigargin | 2000 |
Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cell Line, Transformed; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glomerular Filtration Rate; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Hydralazine; Hypertension; Immunohistochemistry; Kidney Tubules, Proximal; Losartan; Norepinephrine; Oxidative Stress; Proteinuria; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Blockade of angiotensin receptors in the anterior hypothalamic preoptic area lowers blood pressure in DOCA-salt hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Hypertension; Hypothalamus, Anterior; Injections, Intraventricular; Losartan; Male; Preoptic Area; Rats; Rats, Wistar; Receptors, Angiotensin; Reference Values; Sodium Chloride; Vasoconstrictor Agents | 2000 |
Synergistic effects of AT(1) and ET(A) receptor blockade in a transgenic, angiotensin II-dependent, rat model.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Humans; Hypertension; Losartan; Phenylpropionates; Pyrimidines; Rats; Renin | 2000 |
Renin-angiotensin system in two genetically normotensive strains of Lyon rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Diastole; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Kidney Cortex; Male; Norepinephrine; Perindopril; Rats; Renin; Renin-Angiotensin System; Sodium; Systole; Time Factors | 2000 |
Various effects of angiotensin II on amygdaloid neuronal activity in normotensive control and hypertensive transgenic [TGR(mREN-2)27] rats.
Topics: Amygdala; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Evoked Potentials; Hypertension; Neurons; Rats; Rats, Sprague-Dawley | 2000 |
Novel intronic polymorphism (+1675G/A) in the human angiotensin II subtype 2 receptor gene.
Topics: Angiotensin II; Cardiomyopathy, Hypertrophic; Gene Frequency; Humans; Hypertension; Introns; Polymorphism, Genetic; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2000 |
Angiotensin stimulates respiration in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Female; Hypertension; Inspiratory Capacity; Oxygen Consumption; Pulmonary Ventilation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Respiration; Saralasin; Tidal Volume | 2000 |
Effects of perindopril on vascular wall and left ventricular hypertrophy in rats with experimental hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Hypertension; Hypertrophy, Left Ventricular; Male; Mesenteric Artery, Superior; Perindopril; Random Allocation; Rats; Rats, Sprague-Dawley | 1998 |
[Clinical efficacy of losartan: are there any differences between angiotensin II type I receptor antagonists and other drugs?].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Losartan; Receptors, Angiotensin | 2000 |
Short treatments of normotensive and hypertensive rats by angiotensin II and nitric oxide inhibitor induce an increase of noradrenaline sensitivity in isolated vena portae preparations.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Drug Interactions; Ergotamine; Hypertension; In Vitro Techniques; Male; Minoxidil; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Portal Vein; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 2000 |
Proapoptotic and growth-inhibitory role of angiotensin II type 2 receptor in vascular smooth muscle cells of spontaneously hypertensive rats in vivo.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Cell Division; Enalapril; Hypertension; Losartan; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Receptors, Angiotensin | 2000 |
Activation of MAPKs in proximal tubule cells from spontaneously hypertensive and control Wistar-Kyoto rats.
Topics: Angiotensin II; Animals; Hypertension; Kidney Tubules; Mitogen-Activated Protein Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2000 |
Tissue angiotensin II and endothelin-1 modulate differently the response to flow in mesenteric resistance arteries of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Viscosity; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Imidazoles; Losartan; Mesenteric Arteries; Muscle Tonus; Perindopril; Phenylpropionates; Pyridines; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Splanchnic Circulation; Vascular Resistance; Vasodilation | 2000 |
Increased central AT(1)-receptor activation, not systemic vasopressin, sustains hypertension in ANP knockout mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Female; Hormone Antagonists; Hypertension; Injections, Intravenous; Losartan; Male; Mice; Mice, Knockout; Paraventricular Hypothalamic Nucleus; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasopressins | 2000 |
Inability to induce hypertension in normotensive rat expressing AT(1) receptor antisense.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Drinking; Female; Gene Transfer Techniques; Hypertension; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Renal Circulation; Time Factors; Vasoconstriction | 2000 |
An angiotensin system in the anterior hypothalamic area anterior is involved in the maintenance of hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensins; Animals; Anterior Hypothalamic Nucleus; Antihypertensive Agents; Blood Pressure; Carbachol; Hypertension; Losartan; Male; Microinjections; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2000 |
Different regulation of cardiac and renal corticosteroid receptors in aldosterone-salt treated rats: effect of hypertension and glucocorticoids.
Topics: Adrenalectomy; Age Factors; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blotting, Western; Collagen; Glucocorticoids; Heart; Hypertension; Kidney; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Steroid; RNA, Complementary; Sodium Chloride; Spironolactone; Time Factors | 2000 |
Differential effects of sera from normotensive and hypertensive pregnant women on Ca(2+) metabolism in normal vasular smooth muscle cells.
Topics: Adult; Angiotensin II; Animals; Calcium; Cells, Cultured; Female; Humans; Hypertension; Intracellular Membranes; Muscle, Smooth, Vascular; Osmolar Concentration; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Sprague-Dawley; Reference Values | 2000 |
Reduction of plasma angiotensin II to normal levels by antisense oligodeoxynucleotides against liver angiotensinogen cannot completely attenuate vascular remodeling in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Aorta; Blood Pressure; Blood Vessels; Collagen; Hypertension; Liver; Oligonucleotides, Antisense; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; RNA, Messenger; Tunica Media | 2000 |
Transforming growth factor-beta1 modulates angiotensin II-induced calcium release in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Binding Sites; Biological Transport; Calcium; Cells, Cultured; Enzyme Inhibitors; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Thapsigargin; Transforming Growth Factor beta | 2000 |
Association between the molecular pathobiology of essential hypertension and thrombotic diseases.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Coronary Disease; Disease Models, Animal; Humans; Hypertension; Mice; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Thromboplastin; Thrombosis | 2000 |
Basilar artery remodelling in the genetically hypertensive rat: effects of nitric oxide synthase inhibition and treatment with valsartan and enalapril.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Basilar Artery; Blood Pressure; Brain; Enalapril; Enzyme Inhibitors; Hypertension; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Stroke; Tetrazoles; Valine; Valsartan; Ventricular Function, Left | 2000 |
Intrarenal angiotensin II augmentation in angiotensin II dependent hypertension.
Topics: Angiotensin II; Animals; Endosomes; Hypertension; Intracellular Membranes; Kidney; Receptors, Angiotensin; Renal Artery Obstruction | 2000 |
Cardiovascular responses to glutamate and angiotensin II in ventrolateral medulla of hypertension induced by chronic inhibition of nitric oxide.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Enzyme Inhibitors; Glutamic Acid; Heart Rate; Hypertension; Male; Medulla Oblongata; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Time Factors | 2000 |
Impairment of pressure-natriuresis and renal autoregulation in ANG II-infused hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Diuresis; Glomerular Filtration Rate; Homeostasis; Hypertension; Kidney; Kidney Medulla; Male; Natriuresis; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renal Circulation | 2000 |
Afferent arteriolar reactivity to angiotensin II is enhanced during the early phase of angiotensin II hypertension.
Topics: Angiotensin II; Animals; Arterioles; Homeostasis; Hypertension; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Renal Circulation; Time Factors; Vasoconstrictor Agents | 2000 |
Alterations in sarcoplasmic reticulum and angiotensin II receptor type 1 gene expression in spontaneously hypertensive rat hearts.
Topics: Angiotensin II; Animals; Calcium-Transporting ATPases; Gene Expression Regulation; Hypertension; Male; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sarcoplasmic Reticulum | 1999 |
Comprehensive analysis of the renin-angiotensin gene polymorphisms with relation to hypertension in the Japanese.
Topics: Angiotensin II; Cytochrome P-450 CYP11B2; Female; Gene Frequency; Genotype; Humans; Hypertension; Japan; Male; Middle Aged; Odds Ratio; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptors, Angiotensin; Renin-Angiotensin System; Sex Characteristics | 2000 |
ACE inhibition and AT(1) receptor blockers: efficacy and duration in hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Blood Pressure Determination; Circadian Rhythm; Delayed-Action Preparations; Evidence-Based Medicine; Humans; Hypertension; Losartan; Patient Compliance; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2000 |
Spectrum of use for the angiotensin-receptor blocking drugs.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Treatment Outcome; Vasoconstriction | 1999 |
Improvement of endothelial dysfunction as a surrogate endpoint in the treatment of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diagnostic Imaging; Endothelium, Vascular; Humans; Hypertension; NF-kappa B; Nitric Oxide; Vascular Diseases; Vascular Resistance; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2000 |
Enhanced antinatriuresis in response to angiotensin II in essential hypertension.
Topics: Adult; Angiotensin II; Humans; Hypertension; Male; Natriuresis; Reference Values | 2000 |
CC chemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Biomarkers; Cell Movement; Endothelium, Vascular; Hypertension; Hypertrophy; Macrophages; Mice; Mice, Inbred C57BL; Receptor, Macrophage Colony-Stimulating Factor; Receptors, CCR2; Receptors, Chemokine; Vasculitis; Vasoconstrictor Agents | 2000 |
Contribution of angiotensin-(1-7) to blood pressure regulation in salt-depleted hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Blood Pressure Determination; Diet, Sodium-Restricted; Dipeptides; Dose-Response Relationship, Drug; Hypertension; Male; Peptide Fragments; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin | 2000 |
Different activation of vascular mitogen-activated protein kinases in spontaneously and DOCA-salt hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Desoxycorticosterone; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Hypertension; In Vitro Techniques; Losartan; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Endothelin; Sodium Chloride; Vasoconstrictor Agents | 2000 |
[Cardiac and vascular hypertrophy in hypertension due to angiotensin II. Effect of losartan and bosentan].
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Carotid Arteries; Endothelin Receptor Antagonists; Endothelins; Follow-Up Studies; Hypertension; Hypertrophy; Losartan; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sulfonamides | 2000 |
Angiotensin II-induced cardiac hypertrophy is associated with different mitogen-activated protein kinase activation in normotensive and hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Enzyme Activation; Female; Hypertension; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Myosin Heavy Chains; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Renin; Stress, Mechanical; Transgenes; Vasoconstrictor Agents | 2000 |
Baroreflexes prevent neurally induced sodium retention in angiotensin hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Carotid Sinus; Denervation; Diuresis; Dogs; Female; Heart Rate; Hemodynamics; Hypertension; Kidney; Phenylephrine; Potassium; Renin; Sinoatrial Node; Sodium; Sympathetic Nervous System; Urinary Bladder; Vagus Nerve | 2000 |
Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 2000 |
Angiotensin II AT(1) blockade normalizes cerebrovascular autoregulation and reduces cerebral ischemia in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Homeostasis; Hypertension; Infarction, Middle Cerebral Artery; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2000 |
Minimizing the progression of kidney disease. Introduction.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetic Angiopathies; Disease Progression; Diuretics; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Patient Care Planning; Renin-Angiotensin System | 2000 |
Cardiac vagal responsiveness during development in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Age Factors; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atenolol; Baroreflex; Bradycardia; Electric Stimulation; Heart; Heart Rate; Hypertension; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Respiration; Respiration, Artificial; Vagus Nerve | 2000 |
Release of nitric oxide after acute hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Aorta, Thoracic; Enzyme Inhibitors; Hypertension; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Phenylephrine; Rats; Rats, Wistar; Vasoconstrictor Agents | 2000 |
Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization.
Topics: Angiotensin II; Animals; Aorta; Hypertension; Hypertrophy; Mesenteric Arteries; Muscle, Smooth, Vascular; Mutagens; Polyploidy; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Zucker; Recombinant Proteins; Up-Regulation | 2000 |
Cardiac aldosterone production in genetically hypertensive rats.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Corticosterone; Cytochrome P-450 CYP11B2; Heart Ventricles; Hypertension; In Vitro Techniques; Mineralocorticoid Receptor Antagonists; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; RNA, Messenger; Spironolactone | 2000 |
Important role of angiotensin II-mediated c-Jun NH(2)-terminal kinase activation in cardiac hypertrophy in hypertensive rats.
Topics: Acute Disease; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Blood Pressure; Cardiomegaly; Chronic Disease; DNA; Heart Rate; Hypertension; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Organ Size; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Transcription Factor AP-1 | 2000 |
Development of hypertension induced by subpressor infusion of angiotensin II: role of sensory nerves.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Body Weight; Calcitonin Gene-Related Peptide; Capsaicin; Ganglia, Spinal; Hypertension; Infusion Pumps; Injections, Subcutaneous; Male; Neurons, Afferent; Potassium; Rats; Rats, Wistar; RNA, Messenger; Sodium; Sympathectomy, Chemical; Urinalysis | 2000 |
Angiotensin II-induced hypertension: contribution of Ras GTPase/Mitogen-activated protein kinase and cytochrome P450 metabolites.
Topics: Alkyl and Aryl Transferases; Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Enzyme Inhibitors; Flavonoids; Hypertension; Kidney; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mixed Function Oxygenases; ras Proteins; Rats; Rats, Sprague-Dawley; Triazoles | 2000 |
Upregulation of p67(phox) and gp91(phox) in aortas from angiotensin II-infused mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Blotting, Western; Hypertension; In Vitro Techniques; Infusions, Parenteral; Losartan; Luminescent Measurements; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidases; Organ Specificity; Phosphoproteins; Superoxides; Up-Regulation | 2000 |
Testosterone increases blood pressure and cardiovascular and renal pathology in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Captopril; Collagen; Coronary Vessels; Hydralazine; Hypertension; Kidney Glomerulus; Male; Myocardium; Orchiectomy; Rats; Rats, Inbred SHR; Testosterone | 2000 |
Metformin treatment corrects vascular insulin resistance in hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Nitric Oxide; Norepinephrine; Rats; Rats, Sprague-Dawley; Vasoconstriction | 2000 |
Effects of the AT1 receptor antagonist on adhesion molecule expression in leukocytes and brain microvessels of stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Brain; Cell Adhesion Molecules; Cerebral Veins; Hypertension; Leukocytes; Male; Microcirculation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2000 |
Effect of ovariectomy and hormone replacement therapy on small artery biomechanics in angiotensin-induced hypertension in rats.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Elasticity; Estradiol; Female; Hormone Replacement Therapy; Hypertension; Medroxyprogesterone Acetate; Menopause; Ovariectomy; Progesterone Congeners; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Weight Gain | 2000 |
Angiotensin II infused intrarenally causes preglomerular vascular changes and hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hypertension; Infusions, Intra-Arterial; Kidney; Losartan; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Renal Artery; Renal Circulation; Vascular Resistance | 2000 |
[Gestational hypertension (GH) and a1166c polymorphism of angiotensin II type 1 receptor].
Topics: Adolescent; Adult; Angiotensin II; DNA Mutational Analysis; Female; Gene Expression; Humans; Hypertension; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; Pregnancy Complications, Cardiovascular; Receptors, Angiotensin | 2000 |
Angiotensin II-induced changes in G-protein expression and resistance of renal microvessels in young genetically hypertensive rats.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Blotting, Western; Cyclic AMP; Glomerular Filtration Rate; GTP-Binding Proteins; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Regional Blood Flow; Renal Circulation; Urination; Vascular Resistance | 2000 |
Myocardial cell death in human diabetes.
Topics: Angiotensin II; Apoptosis; Cardiomegaly; Diabetes Mellitus, Type 2; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Tyrosine | 2000 |
In vivo activation of rat aortic platelet-derived growth factor and epidermal growth factor receptors by angiotensin II and hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Enalapril; ErbB Receptors; Hypertension; Infusions, Intravenous; Male; Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Perindopril; Phosphorylation; Rats; Rats, Inbred SHR; Receptors, Platelet-Derived Growth Factor | 2000 |
Mechanisms of increased susceptibility to angiotensin II-induced apoptosis in ventricular cardiomyocytes of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Caspase 3; Caspases; Cells, Cultured; Enzyme Activation; Heart; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Tumor Suppressor Protein p53 | 2000 |
Cysteinyl leukotrienes are involved in angiotensin II-induced contraction of aorta from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Culture Techniques; Dose-Response Relationship, Drug; Hypertension; Leukotrienes; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; SRS-A; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Acute hypertension inhibits thirst stimulated by ANG II, hyperosmolality, or hypovolemia in rats.
Topics: Acute Disease; Angiotensin II; Animals; Blood Pressure; Drinking; Drinking Behavior; Endothelin-1; Hypertension; Hypovolemia; Infusions, Intravenous; Male; Osmotic Pressure; Phenylephrine; Polyethylene Glycols; Potassium; Pressoreceptors; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Sodium; Solvents; Thirst; Urine; Vasoconstrictor Agents | 2001 |
Modulation of the baroreflex control of heart rate by angiotensin-(1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Baroreflex; Blood Pressure; Heart Rate; Hypertension; Male; Microinjections; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Angiotensin; Solitary Nucleus | 2000 |
New method for imaging innervation of the renal preglomerular vasculature. Alterations in hypertensive rats.
Topics: Adrenergic Fibers; Angiotensin II; Animals; Arteries; Disease Models, Animal; Hypertension; Immunohistochemistry; Kidney; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Synaptophysin | 2000 |
Arterial remodeling in chronic sinoaortic-denervated rats.
Topics: Angiotensin II; Animals; Aorta; Arteries; Blood Pressure; Carotid Sinus; Denervation; Heart Rate; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 2001 |
Endothelial dysfunction and oxidative stress during estrogen deficiency in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Endothelium, Vascular; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Free Radicals; Hypertension; Irbesartan; Ovariectomy; Oxidative Stress; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tetrazoles; Up-Regulation | 2001 |
Angiotensin II-induced hypertension accelerates the development of atherosclerosis in apoE-deficient mice.
Topics: Angiotensin II; Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Diet, Atherogenic; Hypertension; Mice; Mice, Knockout; Norepinephrine | 2001 |
Effects of salt intake and angiotensin II on vascular reactivity to endothelin-1.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Hemodynamics; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sodium, Dietary; Vasoconstrictor Agents | 2001 |
Opposite regulation of brain angiotensin type 1 and type 2 receptors in cold-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Autoradiography; Brain; Cold Temperature; Hypertension; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
AT(1) receptor blockers prevent sympathetic hyperactivity and hypertension by chronic ouabain and hypertonic saline.
Topics: Air Movements; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Chronic Disease; Guanabenz; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Male; Ouabain; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Saline Solution, Hypertonic; Stress, Physiological; Sympathetic Nervous System; Vasoconstrictor Agents | 2001 |
Expression of angiotensinogen mRNA and protein in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Base Sequence; Blotting, Western; DNA Primers; Gene Expression; Hypertension; Immunohistochemistry; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 2001 |
[What is Na+/H+ exchanger guilty of in cardiology?].
Topics: Acidosis; Angiotensin II; Animals; Bicarbonates; Calcium; Carbon Dioxide; Cell Membrane Permeability; Diabetes Mellitus; Endothelins; HEPES; Humans; Hydrogen-Ion Concentration; Hypertension; Hypertrophy, Left Ventricular; Myocardial Contraction; Myocardial Reperfusion; Myocardium; Protons; Sodium Channels; Sodium-Hydrogen Exchangers | 2000 |
[The autonomic nervous system and hypertension: quid novi?].
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Humans; Hypertension | 2000 |
[The effects of ACE inhibitor treatment and ACE gene polymorphism on erythropoiesis in chronic hemodialysis patients].
Topics: Adult; Aged; Anemia; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bone Marrow; Depression, Chemical; Erythropoietin; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Recombinant Proteins; Renal Dialysis | 2000 |
High salt intake and the brain renin--angiotensin system in Dahl salt-sensitive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Brain; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hypertension; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Ouabain; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium, Dietary; Spectrometry, Fluorescence | 2001 |
Influence of sodium intake on the reliability of active renin as a measure of the renin-angiotensin system in essential hypertension.
Topics: Angiotensin II; Angiotensinogen; Enzyme Precursors; Humans; Hypertension; Immunoradiometric Assay; Renin; Renin-Angiotensin System; Reproducibility of Results; Sodium Chloride, Dietary; Supine Position | 2001 |
Effects of TCV-116 on endothelin-1 and PDGF A-chain expression in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Body Weight; Collagen; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Hemodynamics; Hypertension; Male; Organ Size; Platelet-Derived Growth Factor; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Ventricular Remodeling | 2001 |
[Pathophysiological roles of angiotensin in the pathogenesis of hypertension and cardiovascular remodeling].
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Humans; Hypertension; Mice; Mice, Knockout; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2000 |
Effects of nitric oxide synthase inhibition on angiotensin receptors and metabolism in the pregnant hypertensive rat.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Metabolic Clearance Rate; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Random Allocation; Rats; Rats, Inbred SHR; Receptors, Angiotensin | 2001 |
Control of renin secretion from adrenal gland in transgenic Ren-2 and normal rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Disease Models, Animal; Enalapril; Enzyme Precursors; Female; Ganglionic Blockers; Gene Dosage; Hexamethonium; Histamine; Hypertension; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renin; Vasoconstrictor Agents | 2001 |
Angiotensin II increases neurogenic nitric oxide metabolism in mesenteric arteries from hypertensive rats.
Topics: Angiotensin II; Animals; Electric Stimulation; Hypertension; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred SHR; Saralasin; Superoxide Dismutase; Superoxides | 2001 |
Structural vascular changes in hypertension: role of angiotensin II, dietary sodium supplementation, and sympathetic stimulation, alone and in combination in rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Drug Synergism; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Specific Pathogen-Free Organisms; Sympathetic Nervous System | 2001 |
Antisense inhibition of thyrotropin-releasing hormone reduces arterial blood pressure in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Disease Models, Animal; DNA, Antisense; Hypertension; Male; Oligonucleotides, Antisense; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Thyroid Hormones; Thyrotropin-Releasing Hormone | 2001 |
Antisense inhibition of brain renin-angiotensin system decreased blood pressure in chronic 2-kidney, 1 clip hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Blood Pressure; Brain; Chronic Disease; Hypertension; Hypertension, Renovascular; Hypothalamus; Injections, Intraventricular; Male; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Time Factors | 2001 |
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
Topics: Acetylcholine; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Dinoprost; Disease Models, Animal; Endothelium, Vascular; F2-Isoprostanes; Humans; Hypertension; Ketone Oxidoreductases; Male; Nitrates; Nitrites; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Renin; Superoxide Dismutase; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilation | 2001 |
Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Baroreflex; Blood Pressure; Brain; Circadian Rhythm; Heart Rate; Hypertension; Locomotion; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Telemetry; Time Factors | 2001 |
Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat.
Topics: Angiotensin II; Animals; Blood Pressure; Fibrosis; Furosemide; Gene Transfer Techniques; Genetic Therapy; Genotype; Hypertension; Kidney Glomerulus; Kidney Medulla; Kidney Tubules; Necrosis; Norepinephrine; Proteinuria; Rats; Rats, Inbred BN; Rats, Inbred Dahl; Renal Artery; Renin; Sclerosis; Sodium Chloride; Sodium, Dietary; Vascular Resistance | 2001 |
p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotensin II in SHR but not in WKY.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Collagen; Enzyme Activation; Hypertension; Imidazoles; Irbesartan; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Procollagen; Proline; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Thymidine | 2001 |
Workshop: mechanisms and cardiovascular damage in hypertension.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Cardiovascular System; Cell Nucleus; Disease Models, Animal; Hypertension; I-kappa B Kinase; Inflammation; Models, Chemical; Muscle, Smooth, Vascular; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Renin-Angiotensin System; Signal Transduction | 2001 |
Angiotensin II signaling to phospholipase D in renal microvascular smooth muscle cells in SHR.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Brefeldin A; Cells, Cultured; Hypertension; Models, Chemical; Muscle, Smooth, Vascular; Phospholipase D; Protein Synthesis Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; RNA, Messenger; Signal Transduction | 2001 |
Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneously hypertensive rats studied in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arterioles; Bradykinin; Drug Synergism; Hypertension; Male; Mesenteric Arteries; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilation | 2001 |
Cardiomyocytes bind and activate native human prorenin : role of soluble mannose 6-phosphate receptors.
Topics: Amniotic Fluid; Angiotensin II; Animals; Animals, Newborn; Blood; Cells, Cultured; Enzyme Activation; Enzyme Precursors; Female; Follicular Fluid; Glycosylation; Humans; Hypertension; Kidney; Male; Myocardium; Ovary; Phosphorylation; Rats; Rats, Wistar; Receptor, IGF Type 2; Recombinant Proteins; Renal Artery Obstruction; Renin | 2001 |
Effect of N-acetyl-seryl-aspartyl-lysyl-proline on DNA and collagen synthesis in rat cardiac fibroblasts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Division; Cells, Cultured; Collagen; DNA; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Oligopeptides; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
Prevention of hypertension by irbesartan in Dahl S rats relates to central angiotensin II type 1 receptor blockade.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Brain; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Irbesartan; Male; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles | 2001 |
The peripheral renin-angiotensin system is not involved in the hypertension of sheep exposed to prenatal dexamethasone.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dexamethasone; Female; Glucocorticoids; Hypertension; Irbesartan; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Sheep; Tetrazoles; Vasoconstrictor Agents | 2001 |
Should new drugs be used without outcome data? Implications of Allhat and Elite II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Drug Approval; Humans; Hypertension | 2001 |
Angiotensin II-induced hypertension in bradykinin B2 receptor knockout mice.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Glomerular Filtration Rate; Hypertension; Infusion Pumps, Implantable; Mice; Mice, Knockout; Nitric Oxide Synthase; Norepinephrine; Organ Size; Receptor, Bradykinin B2; Receptors, Bradykinin; Renal Circulation; Time Factors; Vasoconstriction | 2001 |
Temporary treatment of prepubescent rats with angiotensin inhibitors suppresses the development of hypertensive nephrosclerosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Gene Expression; Genetic Predisposition to Disease; Hydralazine; Hypertension; Indans; Kidney; Male; Nephrosclerosis; Proteinuria; Rats; Rats, Inbred SHR; Renin; Stroke; Tetrazoles; Time Factors; Vasodilator Agents | 2001 |
Hormone replacement therapy increases plasma level of angiotensin II in postmenopausal hypertensive women.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Bradykinin; Female; Hormone Replacement Therapy; Humans; Hypertension; Middle Aged; Peptidyl-Dipeptidase A; Postmenopause; Renin | 2001 |
Enhanced renal expression of preproendothelin mRNA during chronic angiotensin II hypertension.
Topics: Angiotensin II; Animals; Atrasentan; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Gene Expression Regulation; Glomerular Filtration Rate; Hemodynamics; Hypertension; Infusions, Intravenous; Kidney; Kidney Cortex; Kidney Medulla; Male; Protein Precursors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Renal Circulation; RNA, Messenger; Transcription, Genetic; Urodynamics | 2001 |
Fos protein is required for the re-expression of angiotensin II type 1 receptors in the nucleus tractus solitarii after baroreceptor activation in the rat.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Microinjections; Oligonucleotides, Antisense; Pressoreceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solitary Nucleus; Time Factors | 2001 |
Differential activation of extracellular signal-regulated protein kinase 1/2 and p38 mitogen activated-protein kinase by AT1 receptors in vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hypertension; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; RNA, Messenger; Vasoconstrictor Agents | 2001 |
Angiotensin II receptor antagonists: new paradigms in the treatment of hypertension. Introduction.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Humans; Hypertension; Telmisartan | 2001 |
Pressure, platelets, and plaque: the central role of angiotensin II in cardiovascular pathology. Concluding comment.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiovascular Diseases; Fibrinolysis; Humans; Hypertension; Imidazoles; Olmesartan Medoxomil; Renin-Angiotensin System; Tetrazoles | 2001 |
12-Hydroxyeicosatetraenoic acid potentiates angiotensin II-induced pressor response in rats.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Rats; Time Factors | 2001 |
Additive hypotensive and anti-albuminuric effects of angiotensin-converting enzyme inhibition and angiotensin receptor antagonism in diabetic spontaneously hypertensive rats.
Topics: Albuminuria; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Drug Therapy, Combination; Gene Expression; Hypertension; Irbesartan; Kidney; Rats; Rats, Inbred SHR; Renin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Enhancement of angiotensinogen expression in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensins; Animals; Blood Pressure; Blotting, Western; Body Weight; Diet; Disease Models, Animal; Hypertension; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sodium, Dietary | 2001 |
[Changes of mitogen-activated protein kinase activity in cardiac tissues, Ang II and cardiac hypertrophy in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Cardiomegaly; Hypertension; In Vitro Techniques; Male; Mitogen-Activated Protein Kinases; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1998 |
Combined effects of AT(1) and ET(A) receptor antagonists, candesartan, and A-127722 in DOCA-salt hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Desoxycorticosterone; Disease Models, Animal; Drug Therapy, Combination; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Natriuresis; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2000 |
Endothelial and myocyte apoptosis--role of angiotensin II.
Topics: Angiotensin II; Apoptosis; Endothelium, Vascular; Humans; Hypertension; In Vitro Techniques; Losartan; Muscle, Smooth; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2001 |
Effect of angiotensin peptides on PAI-1 expression and production in human adipocytes.
Topics: Adipocytes; Adult; Angiotensin II; Angiotensin III; Cells, Cultured; Female; Fibrinolysis; Gene Expression; Humans; Hypertension; Middle Aged; Obesity; Plasminogen Activator Inhibitor 1; Renin-Angiotensin System | 2001 |
Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Animals; Arterioles; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Drug Synergism; Hypertension; Kidney Cortex; Male; Microcirculation; Microsomes; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides; Vasoconstriction | 2001 |
Role of ET(A) receptors in experimental ANG II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Atrasentan; Blood Pressure; Endothelin Receptor Antagonists; Heart Rate; Hypertension; Male; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Sodium Chloride, Dietary; Vasoconstrictor Agents; Water-Electrolyte Balance | 2001 |
Differential ANG II-induced growth activation pathways in mesenteric artery smooth muscle cells from SHR.
Topics: Angiotensin II; Animals; Calcium; Cell Division; Cells, Cultured; Enzyme Activation; Hypertension; Intracellular Membranes; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values | 2001 |
Cysteinyl leukotrienes mediate enhanced vasoconstriction to angiotensin II but not endothelin-1 in SHR.
Topics: Angiotensin II; Animals; Benzoquinones; Endothelin-1; Hypertension; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Male; Potassium Chloride; Propionates; Quinolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation; Vasoconstriction | 2001 |
Role of brain angiotensin II on somatosensory-induced antinatriuresis in hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Capsaicin; Diuresis; Hypertension; Kidney; Losartan; Male; Natriuresis; Neural Pathways; Rats; Rats, Inbred SHR; Rats, Wistar; Renal Circulation; Sodium; Somatosensory Cortex; Sympathetic Nervous System | 2001 |
Effect of extracellular matrix elements on angiotensin II-induced calcium release in vascular smooth muscle cells from normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Cell Cycle; Cells, Cultured; Collagen; Cytoskeletal Proteins; Drug Combinations; Extracellular Matrix Proteins; Fibronectins; Hypertension; Laminin; Male; Muscle, Smooth, Vascular; Paxillin; Phosphoproteins; Proteoglycans; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thapsigargin; Vitronectin | 2001 |
Effect of insulin and angiotensin II on cell calcium in human skin fibroblasts.
Topics: Adult; Angiotensin II; Calcium; Cells, Cultured; Culture Media; Cytosol; Female; Fibroblasts; Humans; Hypertension; Insulin; Insulin Resistance; Male; Middle Aged; Pertussis Toxin; Skin; Thapsigargin; Virulence Factors, Bordetella | 2001 |
Angiotensin-II and endothelin-1 levels in children with renoprival hypertension.
Topics: Adolescent; Angiotensin II; Blood Pressure; Child; Diastole; Endothelin-1; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Nephrectomy; Postoperative Period; Renal Dialysis; Systole | 2001 |
[Modeling of K+ATP channel activity in normotensive and hypertensive animals].
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Guinea Pigs; Hypertension; Muscle, Smooth; Norepinephrine; Potassium Channels | 2000 |
Contribution of central amiloride-sensitive transport systems to the development of hypertension in spontaneously hypertensive rats.
Topics: Amiloride; Angiotensin II; Animals; Blood Pressure; Body Weight; Brain; Carrier Proteins; Diuretics; Ganglionic Blockers; Hexamethonium; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sympathetic Nervous System; Water-Electrolyte Balance | 2001 |
Biomechanical strain induces class a scavenger receptor expression in human monocyte/macrophages and THP-1 cells: a potential mechanism of increased atherosclerosis in hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Apolipoproteins E; Arteriosclerosis; CD36 Antigens; Cell Adhesion; Cell Differentiation; Cells, Cultured; Cholesterol, Dietary; Disease Models, Animal; Humans; Hypertension; Immunohistochemistry; Losartan; Macrophages; Male; Membrane Proteins; Mice; Mice, Knockout; Monocytes; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class A; Scavenger Receptors, Class B; Stress, Mechanical; Tetradecanoylphorbol Acetate; Transcription Factors | 2001 |
Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways.
Topics: Adult; Angiotensin II; Arteries; Cell Division; Humans; Hypertension; Middle Aged; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidases; Phospholipase D; Reactive Oxygen Species; Superoxides; Vascular Resistance | 2001 |
Load versus humoral activation in the genesis of early hypertensive heart disease.
Topics: Angiotensin II; Animals; Catecholamines; Diastole; Disease Models, Animal; Dogs; Endothelin-1; Heart Ventricles; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Kidney; Natriuretic Peptide, Brain; Propranolol; Renin; Systole; Ventricular Dysfunction, Left | 2001 |
Sustained influence of the renal nerves to attenuate sodium retention in angiotensin hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Creatinine; Cyclic GMP; Denervation; Dogs; Female; Heart Rate; Hemodynamics; Hypertension; Kidney; Potassium; Sodium; Sympathetic Nervous System | 2001 |
Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Precursors; Hypertension; In Situ Hybridization; Indoles; Kidney; Kinetics; Mice; Pedigree; Peptidyl-Dipeptidase A; Precipitin Tests; Promoter Regions, Genetic; Rats; Rats, Inbred Strains; Renin; Time Factors; Transcription, Genetic; Transgenes | 2001 |
AT1 receptor antagonist prevents brain edema without lowering blood pressure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain Edema; Cerebral Cortex; Hypertension; Male; Prodrugs; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2000 |
Relative efficacy of an angiotensin II antagonist compared with other antihypertensive agents. Olmesartan medoxomil versus antihypertensives.
Topics: Angiotensin II; Antihypertensive Agents; Atenolol; Captopril; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypertension; Imidazoles; Losartan; Multicenter Studies as Topic; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles | 2001 |
Angiotensin II type 2 receptor is essential for left ventricular hypertrophy and cardiac fibrosis in chronic angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Chronic Disease; Collagen; Diastole; Disease Models, Animal; Echocardiography; Echocardiography, Doppler; Endomyocardial Fibrosis; Fibronectins; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Systole; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Src is an important mediator of extracellular signal-regulated kinase 1/2-dependent growth signaling by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients.
Topics: Adult; Aged; Angiotensin II; Cell Division; DNA; Gene Expression; Humans; Hypertension; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oligodeoxyribonucleotides, Antisense; Oncogene Protein pp60(v-src); Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Transcription Factor AP-1 | 2001 |
[Bilateral renal artery stenosis--a cause of acute pulmonary edema].
Topics: Acute Kidney Injury; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diagnosis, Differential; Enalapril; Heart Failure; Humans; Hypertension; Hypertension, Renovascular; Male; Pulmonary Edema; Renal Artery Obstruction | 2001 |
Cardiovascular regulation in TGR(mREN2)27 rats: 24h variation in plasma catecholamines, angiotensin peptides, and telemetric heart rate variability.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Animals, Genetically Modified; Catecholamines; Heart Rate; Heterozygote; Hypertension; Male; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Time Factors | 2001 |
[Study on changes of plasma substance P in essential hypertension with left ventricular hypertrophy patients and the effect of promoting blood circulation and eliminating phlegm].
Topics: Aged; Angiotensin II; Drugs, Chinese Herbal; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Substance P | 1998 |
Fetal toxic effects and angiotensin-II-receptor antagonists.
Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Female; Humans; Hypertension; Losartan; Pregnancy; Pregnancy Complications, Cardiovascular; Tetrazoles; Valine; Valsartan | 2001 |
Microcirculation in hypertension: a new target for treatment?
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Diuretics; Humans; Hypertension; Microcirculation; Rats; Rats, Inbred SHR | 2001 |
Effect of combination of valsartan with benazepril on blood pressure and left ventricular hypertrophy in SHR.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Drug Therapy, Combination; Hypertension; Hypertrophy, Left Ventricular; Male; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan | 2000 |
Cautions over idiopathic aldosteronism.
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension | 2001 |
Role of nitric oxide in regional blood flow in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Circulation; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitro Compounds; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2001 |
[Effects of anti-atherosclerotic low-sodium diet on dynamics of natural antibodies to angiotensin II, bradykinin and vasopressin in blood of patients with hypertension and obesity].
Topics: Adult; Angiotensin II; Arteriosclerosis; Bradykinin; Diet, Sodium-Restricted; Female; Humans; Hypertension; Immunoenzyme Techniques; Male; Middle Aged; Obesity; Vasopressins | 2001 |
Nitric oxide dependence of renal blood flow in patients with renal artery stenosis.
Topics: Angiography; Angiotensin II; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Reference Values; Renal Artery Obstruction; Renal Circulation; Renin; Severity of Illness Index | 2001 |
Persistent cardiovascular effects of chronic renin-angiotensin system inhibition following withdrawal in adult spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Vessels; Cardiomegaly; Cardiovascular System; Drug Administration Schedule; Heart Rate; Hydralazine; Hypertension; Kidney; Male; Motor Activity; Perindopril; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Vasodilator Agents | 2001 |
[Nephro-protection: role of arterial pressure in progression of renal pathology. Does a nephro-protective effect depend on the choice of antihypertensive drug?].
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diabetes Complications; Diuretics; Follow-Up Studies; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Failure, Chronic; Multicenter Studies as Topic; Prognosis; Risk Factors; Time Factors | 2001 |
Effects of angiotensin II on the renal antioxidant activities of borderline hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Female; Glutathione; Humans; Hypertension; Injections, Subcutaneous; Lipid Peroxides; Male; Oxidoreductases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Vasoconstrictor Agents; Weaning | 2001 |
Blunted renal responses to angiotensin II infusion in lifetime captopril-treated spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Drinking Behavior; Drug Administration Schedule; Hypertension; Injections, Intravenous; Injections, Intraventricular; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2001 |
Different reactivity to angiotensin II of peripheral and renal arteries in spontaneously hypertensive rats: effect of acute and chronic angiotensin converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Sodium, Dietary | 1986 |
Use of a biological peptide pump to study chronic peptide hormone action in transgenic mice. Direct and indirect effects of angiotensin II on the heart.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Body Weight; Heart; Hypertension; In Vitro Techniques; Mice; Mice, Transgenic; Organ Size; Peptides; Protein Transport | 2001 |
Factors derived from adrenals are required for activation of cardiac gene expression in angiotensin II-induced hypertension.
Topics: Adrenal Glands; Angiotensin II; Animals; Gene Expression Regulation; Heart; Hypertension; Male; Rats; Rats, Sprague-Dawley | 2001 |
Characterization of the antihypertensive effect of a thiazide diuretic in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Administration Schedule; Hypertension; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride Symporter Inhibitors; Trichlormethiazide | 2001 |
Endogenous angiotensin II suppresses insulin signaling in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Butadienes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Insulin; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nitriles; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction | 2001 |
Enhanced interaction between renovascular alpha(2)-adrenoceptors and angiotensin II receptors in genetic hypertension.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Brimonidine Tartrate; Captopril; Hypertension; Male; Methoxamine; Nephrectomy; Protein Binding; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Angiotensin; Renal Artery; Renal Circulation; Species Specificity; Vascular Resistance; Vasoconstrictor Agents | 2001 |
Adrenal response to angiotensin II in black hypertension: lack of sexual dimorphism.
Topics: Adrenal Glands; Adult; Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Black People; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Potassium; Potassium, Dietary; Renin; Sex Factors; White People | 2001 |
Effect of angiotensin II synthesis blockade on the hypertensive response to chronic reductions in uterine perfusion pressure in pregnant rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Blood Pressure; Body Weight; Enalapril; Female; Hypertension; Pregnancy; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Uterus | 2001 |
TCV-116 stimulates eNOS and caveolin-1 expression and improves coronary microvascular remodeling in normotensive and angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Capillaries; Caveolin 1; Caveolins; Collagen Type I; Coronary Vessels; Gene Expression; Hypertension; Male; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles | 2001 |
Day-night variation in the in vitro contractility of aorta and mesenteric and renal arteries in transgenic hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Blood Pressure; Circadian Rhythm; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Photoperiod; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Artery; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2001 |
Vascular cell adhesion molecule-1 as a biochemical marker of left ventricular mass in the patients with hypertension.
Topics: Aged; Angiotensin II; Biomarkers; Carotid Arteries; E-Selectin; Echocardiography; Electrocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Intercellular Adhesion Molecule-1; Male; Middle Aged; Severity of Illness Index; Tunica Intima; Vascular Cell Adhesion Molecule-1 | 2001 |
[The sarcoplasmic reticulum Ca2+ handling protein and left ventricular hypertrophy in SHR].
Topics: Angiotensin II; Animals; Calcium-Transporting ATPases; Hypertension; Hypertrophy, Left Ventricular; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 1999 |
Selective effect of tempol on renal medullary hemodynamics in spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Cyclic N-Oxides; Free Radical Scavengers; Hypertension; Kidney Medulla; Organ Size; Rats; Rats, Inbred SHR; Renal Circulation; Spin Labels; Time Factors | 2001 |
Effect of chronic blockade of the kallikrein-kinin system on the development of hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Desoxycorticosterone; Hypertension; Kallikrein-Kinin System; Rats; Rats, Inbred BN; Sodium Chloride, Dietary | 2001 |
Renal cortical vasoconstriction contributes to development of salt-sensitive hypertension after angiotensin II exposure.
Topics: Angiotensin II; Animals; Drug Synergism; Hemodynamics; Hypertension; Immunosuppressive Agents; Kidney; Kidney Cortex; Kidney Glomerulus; Male; Mycophenolic Acid; Rats; Rats, Sprague-Dawley; Sodium Chloride; Vasoconstriction | 2001 |
Beneficial effect of trandolapril on the lifespan of a severe hypertensive model.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Body Weight; Brain; Hypertension; Indoles; Kidney; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride, Dietary; Survival Analysis | 2001 |
[Early prevention of experimental left ventricular hypertrophy in experimental hypertension and angiotensin II levels].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Drug Evaluation, Preclinical; Hypertension; Hypertrophy, Left Ventricular; Male; Peptidyl-Dipeptidase A; Perindopril; Rats; Rats, Sprague-Dawley | 2001 |
Endothelin antagonist reduces hemodynamic responses to vasopressin in DOCA-salt hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Bosentan; Cardiac Output; Desoxycorticosterone; Endothelin-1; Hemodynamics; Hypertension; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Vascular Resistance; Vasoconstrictor Agents | 2001 |
Differential role of kinases in brain stem of hypertensive and normotensive rats.
Topics: Androstadienes; Angiotensin II; Animals; Apnea; Blood Pressure; Brain Stem; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Hypertension; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Wortmannin | 2001 |
Apoptosis and glomerular injury after prolonged nitric oxide synthase inhibition in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Apoptosis; Hypertension; Immunohistochemistry; Kidney; Kidney Glomerulus; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organ Size; Rats; Rats, Inbred SHR; Regional Blood Flow | 2001 |
Peripheral benzodiazepine receptor mapping in rat kidney. Effects of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Hypertension; Immunohistochemistry; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reference Values; Serum Albumin; Tissue Distribution | 2002 |
[PI-3 kinase/AKT/PKB signal transduction pathway in kidneys mediates angiotensin II-induced hypertension].
Topics: Angiotensin II; Animals; Hypertension; Kidney; Male; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; ras GTPase-Activating Proteins; Rats; Signal Transduction | 2001 |
Angiotensin II stimulates alpha-skeletal actin expression in cadiomyocytes in vitro and in vivo in the absence of hypertension.
Topics: Actins; Angiotensin II; Animals; Base Sequence; Cell Differentiation; DNA Primers; Hypertension; In Vitro Techniques; Mice; Mice, Transgenic; Myocardium; Rats; Rats, Wistar; Renin | 2001 |
[Study on the relation between the angiotensin converting enzyme gene and pregnancy induced hypertension].
Topics: Adult; Angiotensin II; Female; Gene Deletion; Humans; Hypertension; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Pregnancy; Pregnancy Complications, Cardiovascular | 2001 |
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy.
Topics: ADAM Proteins; ADAM12 Protein; Angiotensin II; Animals; Aorta, Thoracic; Cardiomegaly; Disease Models, Animal; Disintegrins; Epidermal Growth Factor; ErbB Receptors; Glycine; GTP-Binding Proteins; Heart Ventricles; Heparin-binding EGF-like Growth Factor; Hydroxamic Acids; Hypertension; Intercellular Signaling Peptides and Proteins; Male; Membrane Proteins; Metalloendopeptidases; Phenylephrine; Protease Inhibitors; Protein Processing, Post-Translational; Rats; Signal Transduction; Systole; Transcriptional Activation | 2002 |
Altered PYK2 phosphorylation by ANG II in hypertensive vascular smooth muscle.
Topics: Alkaloids; Angiotensin II; Animals; Aorta, Thoracic; Benzophenanthridines; Calcium; Cells, Cultured; Chelating Agents; Cytosol; Egtazic Acid; Enzyme Inhibitors; Focal Adhesion Kinase 2; Gene Expression; Hypertension; Isoenzymes; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phenanthridines; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents | 2002 |
Hyperaldosteronism: primary versus tertiary.
Topics: Angiotensin II; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Renin | 2002 |
Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Dose-Response Relationship, Drug; Family Health; Germany; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Male; Natriuresis; Potassium; Renin; Renin-Angiotensin System; Sensitivity and Specificity; Sodium, Dietary | 2002 |
[Simvastatin attenuates cardiovascular effects and oxidative stress induced by angiotensin II].
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Blood Pressure; Cardiomegaly; Hypertension; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Simvastatin | 2001 |
[Study on the relation between hypertensive left ventricular hypertrophy in very old people with neurohormonal factors and ventricular arrhythmias].
Topics: Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Arrhythmias, Cardiac; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Incidence; Male; Myocardial Ischemia; Renin | 2000 |
Reduced reactivity of renal microvessels to pressure and angiotensin II in fawn-hooded rats.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Hydronephrosis; Hypertension; Kidney; Male; Perfusion; Rats; Rats, Sprague-Dawley; Rats, Wistar; Renal Artery; Renal Circulation | 2002 |
Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dextrans; Endosomes; Flow Cytometry; Fluoresceins; Hypertension; Kidney; Male; Microvilli; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Systole; Tetrazoles | 2002 |
Regulation and localization of HSP70 and HSP25 in the kidney of rats undergoing long-term administration of angiotensin II.
Topics: Angiotensin II; Animals; Cells, Cultured; Crystallins; Heat-Shock Proteins; Hemin; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Hypertension; Immunohistochemistry; Kidney; Kidney Tubules; Neoplasm Proteins; Norepinephrine; Phosphorylation; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2002 |
Angiotensin II and catecholamines increase plasma levels of 8-epi-prostaglandin F(2alpha) with different pressor dependencies in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Hypertension; Ibuprofen; Male; Norepinephrine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2002 |
Left ventricular structure and diastolic function in subjects with two hypertensive parents.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Case-Control Studies; Catecholamines; Electrocardiography; Family Health; Female; Humans; Hypertension; Insulin Resistance; Male; Parents; Renin; Ventricular Dysfunction, Left; Ventricular Remodeling | 2001 |
Antioxidative properties of acetylsalicylic Acid on vascular tissues from normotensive and spontaneously hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Antioxidants; Aorta; Aspirin; Culture Techniques; Dose-Response Relationship, Drug; Hypertension; Kinetics; Luminescent Measurements; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Vasodilation; Vasodilator Agents | 2002 |
Effects of long-term enalapril and losartan therapy of hypertension on cardiovascular aldosterone.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Drug Administration Schedule; Enalapril; Hypertension; Losartan; Mesenteric Arteries; Myocardium; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Reference Values | 2001 |
Salt-sensitive hypertension resulting from nitric oxide synthase inhibition is associated with loss of regulation of angiotensin II in the rat.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2002 |
Molecular interactions of vasoactive systems in cardiovascular damage.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin Receptor Antagonists; Enzyme Precursors; Fibrosis; Heart; Humans; Hypertension; Kallikrein-Kinin System; Kallikreins; Kidney; Kinins; Myocardium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Bradykinin; Renin; Renin-Angiotensin System; Signal Transduction | 2001 |
1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Cyclic GMP; Dinoprostone; Epoprostenol; Hypertension; Male; Nitric Oxide; Peptide Fragments; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Salts; Thromboxane A2; Thromboxane B2; Time Factors | 2002 |
Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Biological Availability; Biphenyl Compounds; Blood Pressure; Blood Vessels; Disease Models, Animal; Drug Therapy, Combination; Female; Hypertension; Immunohistochemistry; Irbesartan; Male; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide; Phosphoproteins; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Stroke; Superoxides; Tetrazoles | 2002 |
Activation of the cardiac endothelin system in left ventricular hypertrophy before onset of heart failure in TG(mREN2)27 rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Aspartic Acid Endopeptidases; Collagen; Endothelin-1; Endothelin-Converting Enzymes; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Male; Metalloendopeptidases; Models, Animal; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Augmented adrenergic vasoconstriction in hypertensive diabetic obese Zucker rats.
Topics: Angiotensin II; Animals; Arteries; Arterioles; Blood Pressure; Diabetes Mellitus; Endothelins; Heart Rate; Hypertension; Male; Microcirculation; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Obesity; Phentolamine; Propranolol; Rats; Rats, Zucker; Thinness; Vasoconstriction | 2002 |
Temporal regression of myocyte hypertrophy in hypertensive, heart failure-prone rats treated with an AT1-receptor antagonist.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Female; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Myocardium; Rats; Rats, Inbred SHR; Tetrazoles; Time Factors | 2002 |
Comparative effects of the dual ACE-NEP inhibitor MDL-100,240 and ramipril on hypertension and cardiovascular disease in endogenous angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Aorta; Benzazepines; Blood Pressure; Body Weight; Cardiovascular Diseases; Hypertension; In Vitro Techniques; Male; Neprilysin; Organ Size; Pyridines; Ramipril; Rats; Vasoconstriction | 2002 |
Determination of arterial baroreflex-blood pressure control in conscious rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Dose-Response Relationship, Drug; Female; Hypertension; Male; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents | 2002 |
Enhanced response of subfornical organ neurons projecting to the hypothalamic paraventricular nucleus to angiotensin II in spontaneously hypertensive rats.
Topics: Action Potentials; Angiotensin II; Animals; Blood Pressure; Electric Stimulation; Evoked Potentials; Homeostasis; Hypertension; Male; Neural Pathways; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reaction Time; Subfornical Organ | 2002 |
Blunted suppression of plasma renin activity in diabetes.
Topics: Adult; Angiotensin II; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diet, Sodium-Restricted; Feedback; Female; Humans; Hypertension; Male; Middle Aged; Reference Values; Renin | 2000 |
Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Activation; ErbB Receptors; Hypertension; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Inbred SHR; Rats, Inbred WKY; src-Family Kinases; Transcriptional Activation | 2002 |
Sustained activation of the central baroreceptor pathway in angiotensin hypertension.
Topics: Angiotensin II; Animals; Brain Stem; Dogs; Electrolytes; Female; Hemodynamics; Hypertension; Hypothalamus; Immunohistochemistry; Male; Medulla Oblongata; Pressoreceptors; Proto-Oncogene Proteins c-fos | 2002 |
Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Epoxide Hydrolases; Hypertension; Male; Rats; Rats, Sprague-Dawley | 2002 |
Functional significance of activation of calcium/calmodulin-dependent protein kinase II in angiotensin II--induced vascular hyperplasia and hypertension.
Topics: Angiotensin II; Animals; Blood Vessels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Disease Models, Animal; DNA; Enzyme Activation; Hyperplasia; Hypertension; Male; Norepinephrine; Phosphorylation; Rabbits; Rats; Rats, Sprague-Dawley | 2002 |
[Evaluation of the platelet angiotensin receptor in pregnancy complicated by preeclampsia].
Topics: Adult; Angiotensin II; Blood Platelets; Case-Control Studies; Female; Humans; Hypertension; Infant, Newborn; Pre-Eclampsia; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Radioligand Assay; Receptors, Angiotensin; Risk Factors; Statistics, Nonparametric | 2001 |
Posttranscriptional control of BNP gene expression in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Echocardiography; Gene Expression Regulation; Heart Rate; Heart Ventricles; Hypertension; Male; Natriuretic Peptide, Brain; Organ Size; Promoter Regions, Genetic; Protein Binding; Rats; Rats, Sprague-Dawley; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription Factor AP-1 | 2002 |
[Significance of pharmacological blockade of angiotensin II type I receptors for correction of abnormal 24-hour blood pressure profile depending on its variability in patients with arterial hypertension stage II].
Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Imidazoles; Male; Receptor, Angiotensin, Type 1; Thiophenes | 2002 |
Endothelin blockade in angiotensin II hypertension: prevention and treatment studies in the rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Carotid Arteries; Endothelin Receptor Antagonists; Hypertension; Male; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides | 2001 |
Vascular reactivity to angiotensin II alone or combined with a thromboxane A2 mimetic in the isolated perfused kidney of Lyon hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drug Synergism; Genetic Predisposition to Disease; Hypertension; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Vascular Resistance; Vasoconstrictor Agents; Vasomotor System | 2002 |
Dysregulation of angiotensin II synthesis is associated with salt sensitivity in the spontaneous hypertensive rat.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Hypertension; Losartan; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin; Sodium Chloride, Dietary | 2002 |
[Diabetic patient with hypertension takes A-I I blocker. Less likely dialysis].
Topics: Albuminuria; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Clinical Trials as Topic; Diabetes Complications; Diabetic Nephropathies; Humans; Hypertension; Irbesartan; Risk Factors; Tetrazoles | 2002 |
Cardiovascular influences of alpha1b-adrenergic receptor defect in mice.
Topics: Angiotensin II; Animals; Aorta; Arterioles; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Cardiovascular System; Echocardiography; Heart Rate; Heart Ventricles; Hypertension; Male; Mesentery; Mice; Mice, Transgenic; Norepinephrine; Organ Size; Phenylephrine; Receptors, Adrenergic, alpha-1; RNA, Messenger; Vasoconstrictor Agents; Ventricular Remodeling | 2002 |
[Angiotensin II participates in stress-induced high blood pressure via stimulating hypothalamic vasopressin synthesis and release].
Topics: Angiotensin II; Animals; Captopril; Hypertension; Hypothalamus; Male; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Physiological; Vasopressins | 2000 |
[Effects of intracerebroventricular injection of angiotensin II on blood pressure and discharges of habenula nucleus cardiovascular neurons].
Topics: Angiotensin II; Animals; Blood Pressure; Electrophysiology; Female; Habenula; Hypertension; Injections, Intraventricular; Iontophoresis; Male; Neurons; Rats; Rats, Wistar | 2000 |
Effect of AT(1) receptor blockade on cardiac apoptosis in angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspases; Echocardiography; Hypertension; In Situ Nick-End Labeling; Losartan; Male; Myocardium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction | 2002 |
Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats.
Topics: Amides; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; Hemodynamics; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Ribosomal Protein S6 Kinases; RNA, Messenger; Tetrazoles; Ventricular Remodeling | 2002 |
The dual AngII/AVP receptor gene N119S/C163R variant exhibits sodium-induced dysfunction and cosegregates with salt-sensitive hypertension in the Dahl salt-sensitive hypertensive rat model.
Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Chromosome Mapping; Crosses, Genetic; Cyclic AMP; DNA, Complementary; Genes; Genetic Markers; Genetic Predisposition to Disease; Hypertension; Kidney; Ligands; Lod Score; Male; Molecular Sequence Data; Quantitative Trait, Heritable; Rats; Rats, Inbred Dahl; Receptors, Angiotensin; Receptors, Vasopressin; Second Messenger Systems; Sequence Homology; Sodium; Sodium Chloride | 2002 |
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism.
Topics: Administration, Oral; Allopurinol; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Benzofurans; Blood Pressure; Diuretics; Enalapril; Hydrochlorothiazide; Hypertension; Kidney; Losartan; Male; Muscle, Smooth, Vascular; Oxonic Acid; Rats; Rats, Sprague-Dawley; Sodium Chloride Symporter Inhibitors; Sodium Chloride, Dietary; Uric Acid; Uricosuric Agents; Vascular Diseases | 2002 |
Early changes in proteoglycans production by resistance arteries smooth muscle cells of hypertensive rats.
Topics: Angiotensin II; Animals; Cattle; Cell Division; Cells, Cultured; DNA; Fetal Blood; Hypertension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Proteoglycans; Rats; Rats, Inbred SHR; Rats, Wistar; Vascular Resistance | 2002 |
Inhibition of mitogen-activated protein/extracellular signal-regulated kinase improves endothelial function and attenuates Ang II-induced contractility of mesenteric resistance arteries from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Hypertension; Mesenteric Arteries; Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2002 |
Lipid metabolism.
Topics: Angiotensin II; Arteriosclerosis; Cholesterol, LDL; Gene Expression Regulation; Hypertension; Interleukin-6; Lipid Metabolism; Macrophages | 2002 |
Angiotensin II and IGF-I may interact to regulate tubulointerstitial cell kinetics and phenotypic changes in hypertensive rats.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Division; Hypertension; Immunohistochemistry; Insulin-Like Growth Factor I; Kidney; Kidney Tubules; Male; Muscle, Smooth; Phenotype; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Vimentin | 2002 |
Fetal uninephrectomy leads to postnatal hypertension and compromised renal function.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Female; Fetus; Glomerular Filtration Rate; Hormones; Hypertension; Kidney Diseases; Kinetics; Nephrectomy; Renin; Sheep; Sodium Chloride; Urea | 2002 |
Renoprotective effect of chronic adrenomedullin infusion in Dahl salt-sensitive rats.
Topics: Adrenomedullin; Angiotensin II; Animals; Creatinine; Drug Implants; Glomerulonephritis; Hormones; Hypertension; Kidney; Male; Peptides; Proteinuria; Rats; Rats, Inbred Dahl; Renal Insufficiency; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride; Time Factors; Transforming Growth Factor beta | 2002 |
Changes of inducible nitric oxide synthase in aortic cells during the development of hypertension: effect of angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cells, Cultured; Hypertension; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred SHR; Rats, Wistar | 2002 |
[Assessment of drug treatment for hypertension in a health centre as a function of associated chronic pathologies and degree of control of the hypertension].
Topics: Aged; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Confidence Intervals; Cross-Sectional Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors | 2002 |
Aortic smooth muscle cell phenotypic modulation and fibrillar collagen deposition in angiotensin II-dependent hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta; Biphenyl Compounds; Bosentan; Calcium Channel Blockers; Collagen; Dansyl Compounds; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Immunohistochemistry; Irbesartan; Male; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles | 2002 |
Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II.
Topics: Amides; Angiotensin II; Animals; Arachidonic Acid; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mixed Function Oxygenases; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfones; Triazoles; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Renal endothelin in chronic angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Diet, Sodium-Restricted; Endothelins; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2002 |
Renal medullary nitric oxide deficit of Dahl S rats enhances hypertensive actions of angiotensin II.
Topics: Angiotensin II; Animals; Arginine; Blood Pressure; Hypertension; Injections, Intravenous; Kidney Cortex; Kidney Medulla; Male; Nitric Oxide; Nitric Oxide Synthase; Osmolar Concentration; Rats; Rats, Inbred BN; Rats, Inbred Dahl; Regional Blood Flow; Vasoconstrictor Agents | 2002 |
Two ACEs and a heart.
Topics: Angiotensin II; Animals; Blood Pressure; Drosophila melanogaster; Drosophila Proteins; Gene Expression Regulation, Enzymologic; Heart; Heart Diseases; Hypertension; Metalloendopeptidases; Mice; Mice, Knockout; Myocardium; Peptidyl-Dipeptidase A; Rats; X Chromosome | 2002 |
Angiotensin-converting enzyme 2 is an essential regulator of heart function.
Topics: Angiotensin II; Animals; Blood Pressure; Cloning, Molecular; Drosophila melanogaster; Drosophila Proteins; Female; Gene Deletion; Gene Expression Regulation, Enzymologic; Heart; Hypertension; Hypoxia; Male; Metalloendopeptidases; Mice; Mice, Knockout; Myocardial Contraction; Myocardium; Peptidyl-Dipeptidase A; Quantitative Trait, Heritable; Radiation Hybrid Mapping; Rats; Up-Regulation; X Chromosome | 2002 |
Effects of losartan on the blood-brain barrier permeability in long-term nitric oxide blockade-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Blood-Brain Barrier; Coloring Agents; Enzyme Inhibitors; Evans Blue; Hypertension; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 2002 |
Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypertension; Imidazoles; Male; Natriuretic Peptide, Brain; Prodrugs; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Spironolactone; Stroke; Tetrazoles; Time Factors | 2002 |
Antihypertensive persistence and drug class.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Child; Child, Preschool; Diuretics; Drug Utilization; Female; Humans; Hypertension; Infant; Male; Middle Aged; Patient Compliance; Practice Patterns, Physicians'; Retrospective Studies; Saskatchewan; Sex Factors | 2002 |
Radioimmunoassay of plasma renin activity.
Topics: Adult; Angiotensin II; Biological Assay; Evaluation Studies as Topic; Female; Follicular Phase; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hypertension; Iodine Radioisotopes; Kidney; Male; Middle Aged; Radioimmunoassay; Renin | 1976 |
Control of renin release: a review of experimental evidence and clinical implications.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Blood Pressure; Brain; Diuretics; Hemorrhage; Humans; Hypertension; Neurons, Afferent; Posture; Receptors, Adrenergic; Reflex; Renin; Sodium Chloride; Sympathetic Nervous System; Vasodilator Agents | 1976 |
[New concepts on the pathogenesis of atherosclerosis and its practical aspects].
Topics: Angiotensin II; Animals; Arteries; Arteriosclerosis; Cholesterol; Diet, Atherogenic; Endothelium; Haplorhini; Humans; Hypertension; Platelet Aggregation; Rabbits; Smoking; Takayasu Arteritis | 1976 |
The fetal renin-angiotensin system in normal and hypertensive pregnancy.
Topics: Angiotensin II; Body Weight; Female; Fetal Blood; Humans; Hydrogen-Ion Concentration; Hypertension; Infant, Newborn; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1976 |
[Arterial hypertension and chronic hemodialysis].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Kidney Failure, Chronic; Nephrectomy; Renal Dialysis; Renin | 1976 |
Critical opening pressure and reactivity of tail vessels in conscious hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Ganglionic Blockers; Hypertension; Male; Norepinephrine; Rats; Regional Blood Flow; Tail; Vascular Resistance | 1976 |
Introduction to part II of the hypertension symposium. Prorenin, renal hypertension; diuretics and hyperlipidemia; angiotensin receptors and blocking drugs; a new treatment system.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Diuretics; Humans; Hypertension; Hypertension, Renal; Lipids; Rats; Receptors, Angiotensin; Renin | 1976 |
Methodologic problems in plasma renin activity measurements.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Angiotensin II; Angiotensinogen; Dimercaprol; Humans; Hydrogen-Ion Concentration; Hypertension; Isoflurophate; Methods; Middle Aged; Oxyquinoline; Posture; Protease Inhibitors; Radioimmunoassay; Renin; Time Factors | 1976 |
Plasma prorenin: cryoactivation and relationship to renin substrate in normal subjects.
Topics: Angiotensin II; Angiotensinogen; Cold Temperature; Female; Freezing; Humans; Hydrogen-Ion Concentration; Hypertension; In Vitro Techniques; Kidney; Male; Renin; Time Factors | 1976 |
[Essential hypertension: adrenergic control system, renin-angiotensin effector axis, kidney and age].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Angiotensin II; Catecholamines; Diuretics; Humans; Hypertension; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Renin; Vasodilator Agents | 1976 |
Renin and age as determinants of a predominantly betablocker-based antihypertensive drug program.
Topics: Adrenergic beta-Antagonists; Adult; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Feedback; Humans; Hypertension; Middle Aged; Norepinephrine; Oxprenolol; Propranolol; Renin | 1976 |
A beta-blocker-based antihypertensive drug program guided by age and renin.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Angiotensin II; Humans; Hypertension; Middle Aged; Renin | 1976 |
Labetalol (AH5158), a competitive alpha- and beta-receptor blocking drug, in the management of hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Clonidine; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Pheochromocytoma; Propranolol; Substance Withdrawal Syndrome | 1976 |
[beta Blocking agents in arterial hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Hemodynamics; Humans; Hypertension; Propranolol; Renin | 1977 |
The antihypertensive effect of beta-blockers.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Drug Evaluation; Hemodynamics; Humans; Hypertension; Renin | 1977 |
[Hemodynamic changes after angiotensin II blockade by saralasin (author's transl)].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Aorta; Blood Pressure; Cardiac Output; Diet, Sodium-Restricted; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin; Vascular Resistance | 1977 |
Beta-adrenergic blockade, blood pressure, and the renin-angiotensin system.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Sodium | 1977 |
Reversibility of the blood-brain barrier dysfunction induced by acute hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Blood-Brain Barrier; Hydrogen-Ion Concentration; Hypertension; Male; Partial Pressure; Rats | 1978 |
Symposium: Renin-angiotensin-aldosterone system and hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Congresses as Topic; Germany, West; Humans; Hypertension; Renin | 1978 |
[Saralasin in resistant hypertensive crisis (author's transl)].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Clonidine; Female; Furosemide; Glomerulonephritis; Humans; Hypertension; Hypertension, Renovascular; Male; Pheochromocytoma; Renin; Saralasin | 1979 |
Improvement in arterial oxygenation by saralasin infusion in man.
Topics: Adult; Aged; Angiotensin II; Carbon Dioxide; Cardiac Output; Female; Hemodynamics; Humans; Hydrogen-Ion Concentration; Hypertension; Injections, Intra-Arterial; Lung; Male; Middle Aged; Oxygen; Oxygen Consumption; Pulmonary Circulation; Saralasin; Smoking; Vascular Resistance | 1979 |
[Beta blocking agents and arterial hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Female; Hemodynamics; Humans; Hypertension; Renin; Sympathetic Nervous System | 1979 |
Blood-brain barrier to albumin in awake rats in acute hypertension induced by adrenaline, noradrenaline or angiotensin.
Topics: Acute Disease; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Epinephrine; Hydrogen-Ion Concentration; Hypertension; Male; Norepinephrine; Rats; Serum Albumin, Radio-Iodinated | 1979 |
Treatment of hypertension: state of the art in 1979.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Glycolates; Humans; Hydrochlorothiazide; Hypertension; Minoxidil; Pyrimidines; Reserpine; Saralasin; Ticrynafen; United States | 1979 |
Editorial: When to measure renin.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Blood Pressure; Diuretics; Humans; Hypertension; Renin | 1975 |
Letter: Hypotension during angiotensin blockade with saralasin.
Topics: Angiotensin II; Blood Pressure; Heart Rate; Humans; Hypertension; Hypotension; Male; Middle Aged; Saralasin | 1975 |
Letter: Hypotension during angiotensin blockade with saralasin.
Topics: Angiotensin II; Humans; Hypertension; Hypotension, Orthostatic; Infusions, Parenteral; Male; Middle Aged; Posture; Saralasin | 1975 |
Renin-angiotensin system in essential hypertension.
Topics: Angiotensin II; Humans; Hypertension; Kidney; Male; Middle Aged; Radioimmunoassay; Renin | 1975 |
Editorial: Mechanisms in hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Oligopeptides; Rats; Renin; Saralasin; Teprotide | 1975 |
Letter: Saralasin bolus test.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Hypotension; Infusions, Parenteral; Injections, Intravenous; Saralasin | 1975 |
Renin dependency of blood-pressure. Analysis by angiotensin II antagonist P113 in hypertensive patients treated with salt depletion and propranolol.
Topics: Adolescent; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Brain Injuries; Diet, Sodium-Restricted; Female; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Propranolol; Renin; Saralasin; Sodium | 1976 |
Proceedings: Methodological aspects of the renin-angiotensin system.
Topics: Angiotensin II; Humans; Hypertension; Renin | 1976 |
Inactive renin in human plasma.
Topics: Angiotensin II; Humans; Hypertension; Renin | 1976 |
Inactive renin in human plasma.
Topics: Angiotensin II; Humans; Hypertension; Obesity; Renin | 1976 |
Adrenergic receptors and renin release.
Topics: Acebutolol; Angiotensin II; Humans; Hypertension; Receptors, Adrenergic; Receptors, Adrenergic, beta; Renin | 1977 |
Influence of acid treatment of plasma on the renin concentration [proceedings].
Topics: Angiotensin II; Humans; Hydrogen-Ion Concentration; Hypertension; Kinetics; Renin | 1977 |
On the inappropriate in hypertension research.
Topics: Angiotensin II; Animals; Blood Pressure; Diet; Diet, Sodium-Restricted; Humans; Hypertension; Hypertension, Renal; Kidney; Kidney Diseases; Models, Biological; Natriuresis; Paraneoplastic Endocrine Syndromes; Rats; Renin; Research; Sodium; Terminology as Topic; Vasopressins | 1977 |
Saralasin bolus test. Rapid screening procedure for renin-mediated hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Injections, Intravenous; Renin; Saralasin; Time Factors | 1975 |
Direct radioimmunoassay of plasma angiotensin II [proceedings].
Topics: Angiotensin II; Humans; Hypertension; Male; Radioimmunoassay | 1977 |
Sympathetic nervous system and blood-pressure control in essential hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Hormones; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Physical Exertion; Regression Analysis; Renin; Rest; Sympathetic Nervous System | 1978 |
Renin lowers blood-pressure.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Kallikreins; Kidney; Mice; Rats; Renin; Saralasin; Teprotide; Vasodilator Agents | 1978 |
Does renin lower blood-pressure?
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Renin | 1978 |
Captopril in a hyponatraemic hypertensive: need for caution in initiating therapy.
Topics: Angiotensin II; Antihypertensive Agents; Enzyme Inhibitors; Female; Humans; Hypertension; Hyponatremia; Hypotension; Middle Aged; Proline | 1979 |
Influence of beta blockade on the renin-angiotensin-aldosterone system [proceedings].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Metoprolol; Propanolamines; Propranolol; Renin | 1979 |
Idiopathic aldosteronism: a diagnostic artifact?
Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Renin | 1979 |
Modification of vascular responsiveness to angiotensin II in pregnant women by intravenously infused 5alpha-dihydroprogesterone.
Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Cyclooxygenase Inhibitors; Drug Resistance; Female; Humans; Hypertension; Indomethacin; Infusions, Parenteral; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Vasomotor System | 1978 |
Effects of increasing arterial pressure on cerebral blood flow in the baboon: influence of the sympathetic nervous system.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; Female; Haplorhini; Hypertension; Male; Papio; Sympathetic Nervous System | 1979 |
The metabolic clearance rate of dehydroisoandrosterone sulfate. IV. Acute effects of induced hypertension, hypotension, and naturesis in normal and hypertensive pregnancies.
Topics: Adult; Angiotensin II; Blood Pressure; Dehydroepiandrosterone; Female; Furosemide; Humans; Hydralazine; Hypertension; Hypotension; Metabolic Clearance Rate; Muscle, Smooth; Pregnancy; Pregnancy Complications, Cardiovascular | 1976 |
The Distinguished Lecture. Is hypertension essential?
Topics: Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Dehydroepiandrosterone; Humans; Hypertension; Hypertension, Renal; Mineralocorticoids; Natriuresis; Norepinephrine; Patient Compliance; Phenoxybenzamine; Renal Artery Obstruction; Renin; Saralasin; Spironolactone | 1975 |
U vectorcardiograms in left ventricular overloading.
Topics: Adult; Angiotensin II; Aortic Valve Insufficiency; Cardiomegaly; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Vectorcardiography | 1978 |
Differential diagnosis of hypertension in pregnancy.
Topics: Ambulatory Care; Angiotensin II; Blood Pressure; Chronic Disease; Dehydroepiandrosterone; Diagnosis, Differential; Female; Hospitalization; Humans; Hypertension; Metabolic Clearance Rate; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Stimulation, Chemical | 1977 |
A plasma inhibitor of the renin-antirenin reaction and the in vitro generation of angiotensin I.
Topics: Angiotensin II; Animals; Biological Assay; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Complement Fixation Tests; Depression, Chemical; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Humans; Hyperaldosteronism; Hypertension; Plasma; Rabbits; Radioimmunoassay; Renin | 1975 |
Radioimmunoassay of plasma renin activity.
Topics: Angiotensin II; Dimercaprol; Humans; Hypertension; Isoflurophate; Protease Inhibitors; Quality Control; Quinolines; Radioimmunoassay; Renin | 1975 |
Time course of changes in plasma renin after blockade of the renin-system. Studies of conscious and anaesthetized, normal, adrenalectomized and spontaneously hypertensive rats.
Topics: Adrenalectomy; Anesthesia; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Depression, Chemical; Desoxycorticosterone; Female; Hydralazine; Hypertension; Juxtaglomerular Apparatus; Oligopeptides; Rats; Renin; Saralasin; Sodium Chloride; Stimulation, Chemical; Teprotide; Time Factors | 1975 |
Enhanced aldosterone response to angiotensin II in human hypertension.
Topics: Adrenal Cortex; Adrenal Glands; Adult; Aldosterone; Analysis of Variance; Angiotensin II; Female; Humans; Hypertension; Infusions, Parenteral; Male; Receptors, Cell Surface; Secretory Rate; Stimulation, Chemical | 1976 |
The regulation of plasma 18-hydroxy 11-deoxycorticosterone in man.
Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Desoxycorticosterone; Diet; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Radioimmunoassay; Sodium; Stimulation, Chemical | 1976 |
The mechanism of low-renin hypertension: aldosterone response to sodium restriction and upright posture, angiotensin II, ACTH and potassium in patients with hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Diet; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Posture; Potassium; Renin; Sodium | 1976 |
Angiotensin antogonists as pharmacological tools.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Diabetes Insipidus; Gastric Mucosa; Hypertension; Kidney; Peptidyl-Dipeptidase A; Prostaglandins E; Rats; Stomach | 1976 |
Vascular angiotensin receptors and their role in blood pressure control.
Topics: Angiotensin II; Animals; Binding, Competitive; Blood Pressure; Blood Vessels; Dogs; Humans; Hypertension; Nephrectomy; Protease Inhibitors; Rabbits; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Saralasin; Sheep; Sodium | 1976 |
Estimating renin participation in hypertension: superiority of converting enzyme inhibitor over saralasin.
Topics: Adolescent; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Female; Humans; Hypertension; Hypertension, Renal; Kidney Diseases; Male; Middle Aged; Oligopeptides; Renin; Saralasin; Sodium; Teprotide | 1976 |
[Changes of the renin-angiotensin-aldosterone system under contraceptive steroids. Contribution to the etiology of hypertension under hormonal contraceptives].
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Endopeptidases; Female; Humans; Hypertension; Liver; Protein Binding; Renin | 1976 |
Modification of renin reactivity by lipids extracted from normal, hypertensive, and uremic plasma.
Topics: Angiotensin II; Endopeptidases; Humans; Hypertension; Kinetics; Lipids; Phospholipids; Renin; Serum Albumin; Uremia | 1976 |
The renin-angiotensin system and sodium excretion during gestation.
Topics: Angiotensin II; Angiotensinogen; Endopeptidases; Female; Fetal Blood; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Sodium | 1976 |
Endocrine and cardiovascular consequences of angiotensin converting enzyme inhibition.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Hyponatremia; Male; Oligopeptides; Renin | 1977 |
Possible role of renin in hypertension as suggested by renin-sodium profiling and inhibition of converting enzyme.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Depression, Chemical; Humans; Hypertension; Oligopeptides; Posture; Renin; Sodium; Teprotide | 1977 |
The angiotensin I converting enzyme.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antigen-Antibody Reactions; Blood Vessels; Bradykinin; Glycoproteins; Humans; Hypertension; Kidney; Lung; Molecular Weight; Peptidyl-Dipeptidase A; Shock, Hemorrhagic; Species Specificity; Sulfhydryl Reagents; Teprotide | 1977 |
Blockade of renin or angiotensin for understanding human hypertension: a comparison of propranolol, saralasin and converting enzyme blockade.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Volume; Humans; Hypertension; Models, Biological; Natriuresis; Oligopeptides; Propranolol; Renin; Saralasin; Teprotide; Vascular Resistance | 1977 |
The role of the adrenal cortex in human essential hypertension: keynote address.
Topics: 18-Hydroxydesoxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Arteries; Blood Pressure; Blood Volume; Circadian Rhythm; Female; Humans; Hypertension; Ions; Liver; Male; Metabolic Clearance Rate; Middle Aged; Mineralocorticoids; Models, Biological; Posture; Radioimmunoassay; Regional Blood Flow; Renin | 1977 |
Accentuated vascular and endocrine response to SQ 20881 in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Humans; Hypertension; Kidney; Oligopeptides; Regional Blood Flow; Renin; Teprotide | 1977 |
Clinical use of angiotensin blocking agents.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Saralasin | 1977 |
The immediate pressor response to saralasin: a measure of the degree of angiotensin II vascular receptor vacancy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Kinetics; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Saralasin; Teprotide | 1977 |
Plasma levels of 18-hydroxy-11-deoxycorticosterone in essential hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Circadian Rhythm; Desoxycorticosterone; Dexamethasone; Furosemide; Humans; Hypertension; Male; Middle Aged; Potassium Chloride; Reference Values | 1978 |
Angiotensin binding affinity and capacity in the midbrain area of spontaneously hypertensive and normotensive rats.
Topics: Age Factors; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Hypothalamus; Mesencephalon; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Septal Nuclei; Thalamus | 1978 |
Pathogenesis of essential hypertension with low renin: responses of plasma renin activity to various stimulation tests in essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Angiotensin II; Circadian Rhythm; Dexamethasone; Humans; Hypertension; Male; Metyrapone; Middle Aged; Renin | 1978 |
Oral administration of theophylline to modify pressor responsiveness to angiotensin II in women with pregnancy-induced hypertension.
Topics: Angiotensin II; Blood Pressure; Cyclic AMP; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Theophylline | 1978 |
The immediate pressor response to saralasin in man: a test of angiotensin II receptor vacancy.
Topics: Angiotensin II; Blood Pressure; Catecholamines; Diastole; Diet, Sodium-Restricted; Humans; Hypertension; Infusions, Parenteral; Natriuresis; Phentolamine; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Saralasin; Sodium; Time Factors | 1979 |
Alterations of adrenal and uterine angiotensin II receptors during variation of sodium intake and/or experimental hypertension.
Topics: Adrenal Glands; Angiotensin II; Animals; Desoxycorticosterone; Female; Hypertension; Myometrium; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Sodium Chloride; Uterus | 1978 |
Tonin--angiotensin II system in hypertension.
Topics: Angiotensin II; Animals; Antigen-Antibody Reactions; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Indomethacin; Peptide Hydrolases; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats | 1978 |
The adrenal receptor for angiotensin II is altered in essential hypertension.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Hypertension, Renovascular; Middle Aged; Receptors, Angiotensin; Receptors, Cell Surface; Saralasin; Teprotide | 1979 |
[Pathogenesis of arterial hypertension with special reference to the kinins and prostaglandins].
Topics: Angiotensin I; Angiotensin II; Cyclic AMP; Humans; Hypertension; Kallidin; Kallikreins; Kinins; Pressoreceptors; Prostaglandins; Renin | 1979 |
[Tonin-angiotensin II system (author's transl)].
Topics: Angiotensin II; Animals; Brain Chemistry; Hypertension; Peptidyl-Dipeptidase A; Rats; Renin | 1979 |
Direct evidence for a functional block in 18 oxidation in a patient with 17 alpha hydroxylase deficiency.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Angiotensin II; Dexamethasone; Female; Humans; Hypertension; Mineralocorticoids; Oxidation-Reduction; Prednisone; Steroid Hydroxylases | 1978 |
Brain angiotensin II binding and central [Sar1,Ala8]angiotensin responses in normal rats and the New Zealand strain of genetically hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Drinking Behavior; Female; Hypertension; Male; Membranes; Phenobarbital; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Saralasin | 1979 |
Comparison between saralsin and converting enzyme inhibitor in hypertensive disease.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Hypertension, Renovascular; Oligopeptides; Renin; Saralasin; Sodium; Teprotide | 1979 |
[A study on the mechanism of aldosterone secretion in low-renin essential hypertension (author's transl)].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Electrolytes; Female; Furosemide; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Male; Plasma Volume; Renin | 1979 |
[Humoral mechanisms of renin-angiotensin system activation in macrofocal myocardial infarct].
Topics: Adult; Aged; Angiotensin II; Angiotensinogen; Endopeptidases; Enzyme Activation; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Norepinephrine; Renin; Shock, Cardiogenic | 1979 |
Results of adrenal surgery in patients with hypertension, aldosterone excess, and low plasma renin concentration.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Angiotensin II; Blood Pressure; Carbon Dioxide; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium; Renin; Sodium; Spironolactone; Urea | 1975 |
Hyperreactive arterial endothelial cells in atherogenesis and cyclic AMP phosphodiesterase inhibitor in prevention and treatment of atherosclerotic disorders.
Topics: Actomyosin; Angiotensin II; Animals; Arteries; Arteriosclerosis; Bucladesine; Carbon; Chickens; Cyclic AMP; Depression, Chemical; Diethylstilbestrol; Dogs; Endothelium; Estrogens, Conjugated (USP); Hypertension; Macaca mulatta; Phagocytosis; Phosphodiesterase Inhibitors; Phthalazines; Progesterone; Pyridinolcarbamate; Rabbits; Rats | 1975 |
[Hypertension developing in women using oral contraceptions].
Topics: Adolescent; Adult; Age Factors; Angiotensin II; Blood Pressure; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Time Factors | 1975 |
Use of an angiotensin II antagonist (saralasin) in the recognition of "angiotensinogenic" hypertension;.
Topics: Adult; Aged; Alanine; Angiotensin II; Blood Pressure; Furosemide; Humans; Hypertension; Hypertension, Renal; Kidney; Male; Middle Aged; Norepinephrine; Posture; Regional Blood Flow; Renal Veins; Renin; Sarcosine | 1975 |
Editorial: Angiotensin blockade: new pharmacologic tools for understanding and treating hypertension.
Topics: Alanine; Angiotensin II; Diuretics; Humans; Hypertension; Hypertension, Renal; Propranolol; Sarcosine; Sodium | 1975 |
Letter: Use and toxicity of nitroprusside.
Topics: Alanine; Angiotensin II; Animals; Antihypertensive Agents; Cyanides; Ferricyanides; Humans; Hypertension; Rodentia; Sarcosine | 1975 |
Renin: activity, reactivity and concentration in a population survey. Relationship to blood pressure.
Topics: Adult; Angiotensin II; Blood Pressure; Contraceptives, Oral; Creatinine; Diuretics; Estrogens; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Male; Middle Aged; Radioimmunoassay; Renin; Sodium | 1975 |
Renin release, saralasin and the vasodilator-beta-blocker drug interaction in man.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Blood Pressure; Depression, Chemical; Drug Interactions; Humans; Hypertension; Minoxidil; Posture; Propranolol; Receptors, Adrenergic; Renin; Saralasin; Stimulation, Chemical; Vasodilator Agents | 1975 |
[High blood pressure, catecholamines and the sympathetic nervous system. I. Molecular-pharmacological insights].
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Blood Pressure; Catechol O-Methyltransferase; Catecholamines; Homeostasis; Humans; Hypertension; Hypertension, Malignant; Monoamine Oxidase; Norepinephrine; Rats; Renin; Sympathetic Nervous System; Synapses | 1975 |
"Prorenin" in human plasma?
Topics: Angiotensin II; Angiotensinogen; Drug Storage; Enzyme Activation; Enzyme Precursors; Female; Freezing; Humans; Hydrogen-Ion Concentration; Hypertension; In Vitro Techniques; Male; Renin; Sodium; Time Factors | 1975 |
Rectal potential difference in the diagnosis of aldosterone excess.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Desoxycorticosterone; Diet; Electrodes; Female; Fludrocortisone; Glycyrrhiza; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Intestinal Mucosa; Male; Membrane Potentials; Middle Aged; Plants, Medicinal; Potassium; Potentiometry; Rectum; Renin; Sodium; Succinates; Triterpenes | 1975 |
Central nervous system pressor responses in rats susceptible and resistant to sodium chloride hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diet; Drug Synergism; Hypertension; Rats; Rats, Inbred Strains; Sodium Chloride | 1978 |
Neuronal and vascular reactivity in isolated perfused kidneys during the development of spontaneous hypertension.
Topics: Angiotensin II; Animals; Barium; Cocaine; Hypertension; Kidney; Male; Norepinephrine; Rats; Vascular Resistance | 1978 |
Maximal discrimination of renovascular from essential hypertension by the saralasin test.
Topics: Angiotensin II; Blood Pressure; Diagnosis, Differential; Diastole; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Renin; Saralasin | 1978 |
Relationship between the hypotensive and renin-stimulating actions of diuretic therapy in hypertensive patients.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Chlorthalidone; Heart Rate; Humans; Hypertension; Middle Aged; Renin; Saralasin | 1978 |
Renin--angiotensin system in mild essential hypertension. The functional significance of angiotensin II in untreated and thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Benzothiadiazines; Blood Pressure; Diuretics; Female; Humans; Hypertension; Male; Renin; Saralasin; Sodium Chloride Symporter Inhibitors | 1978 |
The role of intrarenal vasoactive substances in the pathogenesis of essential hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Indomethacin; Kallikreins; Male; Middle Aged; Natriuresis; Prostaglandins E; Renin | 1978 |
Plasma noradrenaline and the pressor action of exogenous noradrenaline in normotensive subjects and patients with essential hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Norepinephrine; Renin | 1978 |
Renin angiotensin system and sympathetic nerve activity in mild essential hypertension. The functional significance of angiotensin II in untreated and thiazide treated hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Saralasin; Sympathetic Nervous System | 1979 |
[SAR1, ALA8]-Angiotensin II (saralasin): a symposium. Introduction.
Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Hypertension, Renal; Renin; Saralasin | 1979 |
Drug interactions with saralasin.
Topics: Angiotensin II; Angiotensins; Blood Pressure; Blood Volume; Diuretics; Drug Interactions; Humans; Hypertension; Infusions, Parenteral; Posture; Propranolol; Renin; Saralasin; Sodium; Vasodilator Agents | 1979 |
Angiotensin II profiling with saralasin: summary of Eaton collaborative study.
Topics: Adolescent; Adult; Aged; Angiotensin II; Blood Pressure; Diagnosis, Differential; Evaluation Studies as Topic; Female; Humans; Hypertension; Hypertension, Renovascular; Male; Middle Aged; Racial Groups; Radiography; Renin; Saralasin | 1979 |
Saralasin in human hypertension: the early experience.
Topics: Adolescent; Adult; Aged; Angiotensin II; Binding, Competitive; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Middle Aged; Natriuresis; Posture; Renin; Saralasin; Sodium; Time Factors; Vasoconstriction | 1979 |
Angiotensin blockade by saralasin bolus injection.
Topics: Angiotensin II; Angiotensins; Binding, Competitive; Blood Pressure; Diastole; Female; Humans; Hypertension; Hypertension, Renovascular; Injections, Intravenous; Middle Aged; Posture; Radiography; Renin; Saralasin; Sodium; Stimulation, Chemical; Systole | 1979 |
Angiotensin II blockade: evidence for baroreceptor-mediated renin release and the role of sodium balance.
Topics: Angiotensin II; Diastole; Furosemide; Humans; Hypertension; Hypertension, Renovascular; Infusions, Parenteral; Pressoreceptors; Renal Artery Obstruction; Renin; Saralasin; Sodium; Time Factors | 1979 |
Hemodynamic correlates of saralasin: responsiveness in hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Cardiac Volume; Heart Rate; Hemodynamics; Humans; Hypertension; Middle Aged; Plasma Volume; Pressoreceptors; Renal Artery Obstruction; Renin; Saralasin; Vascular Resistance | 1979 |
Angiotensin II blockade by saralasin in the evaluation of hypertension in children.
Topics: Adolescent; Angiotensin II; Blood Pressure; Child; Child, Preschool; Diagnosis, Differential; Evaluation Studies as Topic; Female; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Infusions, Parenteral; Male; Methods; Nephrectomy; Renin; Saralasin | 1979 |
Hypertension and the renin-angiotensin system following open-heart surgery.
Topics: Adult; Angiotensin II; Cardiopulmonary Bypass; Coronary Artery Bypass; Heart Septal Defects, Atrial; Heart Valve Prosthesis; Humans; Hypertension; Middle Aged; Mitral Valve; Renin | 1977 |
Hemodynamic characteristics of hypertension after coronary bypass surgery and effects of the converting enzyme inhibitor.
Topics: Adult; Angiotensin II; Blood Pressure; Cardiac Output; Coronary Artery Bypass; Enzyme Inhibitors; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Postoperative Complications; Renin; Stroke Volume; Vascular Resistance | 1979 |
Changes in renal inactivation of angiotensin II in rats with hereditary spontaneous hypertension.
Topics: Age Factors; Angiotensin II; Animals; Biological Assay; Blood Pressure; Female; Hypertension; Hypertension, Renal; Kidney; Male; Norepinephrine; Rats; Sex Factors | 1977 |
[Tissue hormones of kidney].
Topics: Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Kallikreins; Kidney; Kinins; Prostaglandins; Renal Artery Obstruction; Renin | 1977 |
Role of the renin-angiotensin system in post-transplantation hypertension in patients with multiple kidneys.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Female; Humans; Hypertension; Infusions, Parenteral; Kidney; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Renal Veins; Renin; Saralasin; Sodium; Transplantation, Homologous | 1978 |
Antihypertensive effect of prostacyclin (PGI2) in experimental hypertension and its influence on plasma renin activity in rats.
Topics: Anesthesia; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Epoprostenol; Hypertension; Hypertension, Renal; Male; Norepinephrine; Prostaglandins; Rats; Renin | 1978 |
Effects of an orally active converting-enzyme inhibitor, SQ 14225, on pressor responses to angiotensin administered into the brain ventricles of spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cerebral Ventricles; Enzyme Inhibitors; Hypertension; Male; Pressoreceptors; Proline; Rats | 1979 |
Historical development of saralasin.
Topics: Angiotensin II; Angiotensins; Animals; Aorta; Binding Sites; Blood Pressure; Dogs; History, 20th Century; Hypertension; Muscle Contraction; Rabbits; Rats; Renin; Saralasin | 1979 |
The vasodepressor action of prostacyclin (PGI2) and its effect on plasma angiotensin II and vasopressin in unanaesthetized normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Epoprostenol; Half-Life; Heart Rate; Hypertension; Male; Prostaglandins; Rats; Vasopressins | 1979 |
Treatment of severe hypertension by repeated bolus injections of labetalol.
Topics: Adolescent; Adult; Aged; Angiotensin II; Blood Pressure; Creatinine; Ethanolamines; Female; Humans; Hypertension; Hypertension, Malignant; Injections, Intravenous; Labetalol; Male; Middle Aged; Renin | 1979 |
Effects of an angiotensin II antagonist; [sarcosine 1, isoleucine 8] angiotensin II, on blood pressure, plasma renin activity and plasma aldosterone concentration in hypertensive and normotensive subjects taking oral contraceptives.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Contraceptives, Oral, Combined; Ethynodiol Diacetate; Female; Humans; Hypertension; Mestranol; Middle Aged; Renin | 1979 |
[Essential arterial hypertension: a presumed culprit, the kidney].
Topics: Angiotensin II; Humans; Hypertension; Kidney; Prostaglandins; Renin; Sodium | 1979 |
Angiotensin-II-stimulated release of thromboxane A2 and prostacyclin (PGI2) in isolated, perfused kidneys of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Epoprostenol; Half-Life; Hypertension; In Vitro Techniques; Indomethacin; Kidney; Male; Platelet Aggregation; Prostaglandins; Rats; Thromboxane A2; Thromboxanes | 1979 |
[Hypotensive effects of diltiazem in DOCA/saline hypertensive rats (author's transl)].
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Desoxycorticosterone; Diltiazem; Drug Combinations; Hypertension; Injections, Intravenous; Male; Norepinephrine; Rats; Renin; Sodium Chloride; Trichlormethiazide | 1979 |
Angiotensin blockade in postoperative paradoxical hypertension of coarctation of the aorta.
Topics: Adolescent; Angiotensin II; Aortic Coarctation; Blood Pressure; Child; Child, Preschool; Humans; Hypertension; Postoperative Complications; Renin; Saralasin | 1979 |
Are idiopathic hyperaldosteronism and low-renin hypertension variants of essential hypertension?
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diagnosis, Differential; Electrolytes; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin | 1979 |
Renal renin release in patients with essential arterial hypertension and with unilateral renal artery stenosis.
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Prostaglandins; Renal Artery Obstruction; Renin | 1979 |
Angiotensin II blockade during combined thiazide-beta-adrenoreceptor-blocker treatment.
Topics: Adult; Angiotensin II; Atenolol; Blood Pressure; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Plasma Volume; Propanolamines; Propranolol; Renin; Saralasin; Sodium | 1979 |
Captopril in hypertension with renal artery stenosis and in intractable hypertension; acute and chronic changes in circulating concentrations of renin, angiotensins I and II and aldosterone, and in body composition.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Proline; Renal Artery Obstruction; Renin; Sodium | 1979 |
Pressor responsiveness to angiotensin in renovascular and steroid hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Female; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Nephrectomy; Rats; Renin | 1979 |
Pathophysiological studies on hypertension induced in rats by kidney extract and salt.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Body Fluids; Hexamethonium Compounds; Hypertension; Kidney; Male; Nephrectomy; Norepinephrine; Rats; Renin; Sodium Chloride; Spironolactone; Tissue Extracts; Water-Electrolyte Balance | 1979 |
The role of renal prostaglandin E and kallikrein in pathogenesis of essential hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Indomethacin; Kallikreins; Kidney; Male; Middle Aged; Posture; Potassium; Prostaglandins E; Renin; Sodium; Spironolactone | 1979 |
The response of plasma renin activity by oral calcium loading in normal subjects and hypertensive and diabetic patients.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Calcium; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hypertension; Male; Renin | 1979 |
[Renin-angiotensin system and hypertension (author's transl)].
Topics: Angiotensin II; Hypertension; Renin | 1979 |
[A review of hypertension with hypopotassemia (author's transl)].
Topics: Angiotensin II; Electrolytes; Female; Humans; Hypertension; Hypokalemia; Male; Renin; Saralasin | 1979 |
An association between the renin angiotensin system, blood pressure and potassium intake.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Humans; Hypertension; Potassium; Renin | 1980 |
[Recent data concerning the physiopathology and classification of arterial hypertension during pregnancy].
Topics: Adult; Angiotensin II; Female; Hemodynamics; Humans; Hypertension; Immunity; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1979 |
[Relation between the hypotensive and renin-stimulating effect of diuretic therapy in hypertensive patients].
Topics: Adult; Aged; Angiotensin II; Chlorthalidone; Diuretics; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Middle Aged; Renin; Saralasin | 1978 |
Extraction and measurement of circulating angiotensins I and II.
Topics: Angiotensin II; Diuretics; Edetic Acid; Humans; Hypertension; Radioimmunoassay; Renin; Sodium Chloride | 1977 |
Furosemide-augmented intravenous urography: results in essential hypertension.
Topics: Adult; Angiography; Angiotensin II; Aortography; Furosemide; Humans; Hypertension; Hypertension, Renal; Kidney; Renal Artery; Renal Veins; Renin; Sodium Chloride; Urography; Vasodilation | 1978 |
Effects of the angiotensin II antagonist 1-sar-8-ala-angiotensin II in hypertension in man.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin; Sodium | 1977 |
Propranolol and newer antihypertensive drugs in the management of hypertension.
Topics: Angiotensin II; Clonidine; Diuretics; Humans; Hypertension; Minoxidil; Prazosin; Propranolol; Saralasin; Vasodilator Agents | 1979 |
[Current state of hypertension studies. Report from the congress of the Council for High Blood Pressure Research, October 1978 in Cleveland, Ohio, on the occasion of the 1st anniversary of the death of Harry Goldblatt (proceedings)].
Topics: Angiotensin II; Animals; Cricetinae; Humans; Hypertension; Kidney; Norepinephrine; Renin | 1979 |
Blood pressure response to an angiotensin II antagonist in patients with acromegaly.
Topics: Acromegaly; Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged | 1979 |
[Effects of an angiotensin II antagonist on systemic hemodynamics and renal functions in various forms of hypertension (author's transl)].
Topics: Adolescent; Adult; Aged; Angiotensin II; Electrolytes; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Renin | 1979 |
Renin-angiotensin system in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Diet; Hypertension; Hypertension, Malignant; Kidney; Male; Rats; Renin; Saralasin; Sodium Chloride; Vascular Resistance | 1979 |
Differential response of hamster cheek pouch microvessels to vasoactive stimuli during the early development of hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cheek; Cricetinae; Hypertension; Norepinephrine; Potassium Chloride | 1979 |
Enhanced adrenal responsiveness to angiotensin II in patients with low renin essential hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Dose-Response Relationship, Drug; Humans; Hypertension; Middle Aged; Potassium; Renin; Sodium | 1979 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Dogs; Emergencies; Female; Heart Diseases; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Pheochromocytoma; Pre-Eclampsia; Pregnancy; Reserpine; Trimethaphan | 1979 |
Response to saralasin and angiotensin's role in essential and renal hypertension.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Hypertension, Renal; Middle Aged; Renin; Saralasin; Sodium | 1979 |
Enhanced renomedullary prostaglandin synthesis in spontaneously hypertensive rats: role of a phospholipase A2.
Topics: Acetylation; Angiotensin II; Animals; Arachidonic Acids; Bradykinin; Hypertension; Kidney Medulla; Male; Malondialdehyde; Phospholipases; Prostaglandins E; Prostaglandins F; Rats | 1979 |
[The saralasin test in the diagnosis of hypertension (author's transl)].
Topics: Adult; Aged; Angiotensin II; Diagnosis, Differential; Furosemide; Humans; Hypertension; Hypertension, Renal; Middle Aged; Renin; Saralasin | 1979 |
[Methods for the early recognition of gestosis].
Topics: Angiotensin II; Embryo Implantation; Female; Humans; Hypertension; Methods; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Time Factors; Uric Acid | 1979 |
Chronobiology of blood pressure.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Circadian Rhythm; Desoxycorticosterone; Epinephrine; Humans; Hypertension; Norepinephrine; Prostaglandins E; Renin; Sodium | 1979 |
[Behavior of the renin-angiotensin-aldosterone system and of electrolyte and water excretion in male and female spontaneously hypertensive and normotensive rats under the influence of a saluretic].
Topics: Aldosterone; Angiotensin II; Animals; Azoles; Circadian Rhythm; Corticosterone; Diuretics; Electrolytes; Female; Hypertension; Male; Natriuresis; Rats; Rats, Inbred Strains; Renin; Sulfonamides; Tetrazoles | 1979 |
The metabolic clearance of aldosterone decreases similarly during infusion of angiotensin II in patients with essential hypertension and in normal subjects.
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Renin | 1979 |
Aldosterone and its stimuli in normal and hypertensive man: are essential hypertension and primary hyperaldosteronism without tumour the same condition?
Topics: Adenoma; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Kidney Neoplasms; Male; Middle Aged; Potassium; Renal Artery Obstruction; Renin; Sodium | 1979 |
Renal vascular resistance and reactivity in the spontaneously hypertensive rat.
Topics: Acetylcholine; Angiotensin II; Animals; Denervation; Hypertension; Kidney; Male; Nervous System; Norepinephrine; Rats; Rats, Inbred Strains; Tyramine; Vascular Resistance | 1979 |
Renin-angiotensin system in mild essential hypertension. The functional significance of angiotensin II in untreated and thiazide-treated hypertensive patients.
Topics: Adult; Angiotensin II; Diuretics; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Male; Plasma Volume; Posture; Renin; Saralasin; Sodium; Sodium Chloride Symporter Inhibitors | 1979 |
Angiotensin II in primary hypertension, relationship to plasma renin activity, aldosterone and urinary electrolytes.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Body Weight; Creatinine; Electrolytes; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Posture; Pulse; Renin | 1979 |
[Hormonal contraceptives and high blood pressure (author's transl)].
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Estrogens; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Pregnancy; Progesterone; Renin | 1979 |
Vascular responsiveness to pressor agents during human pregnancy.
Topics: Aldosterone; Angiotensin II; Aspirin; Female; Hematocrit; Humans; Hypertension; Indomethacin; Pregnancy; Pregnancy Complications, Hematologic; Renin; Sickle Cell Trait; Theophylline; Vasomotor System | 1979 |
The placenta and the renin-angiotensin system.
Topics: Aldosterone; Angiotensin II; Female; Fetus; Humans; Hypertension; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications, Hematologic; Renin | 1979 |
Regulation of the intravascular volume and of the total peripheral resistance in spontaneous hypertensive rats.
Topics: Angiotensin II; Animals; Blood Volume; Hypertension; Norepinephrine; Plasma Volume; Rats; Renin; Sodium; Sympathectomy; Vascular Resistance; Water-Electrolyte Balance | 1979 |
Abnormal adrenal responsiveness and angiotensin II dependency in high renin essential hypertension.
Topics: Adrenal Cortex; Adrenal Cortex Function Tests; Adult; Aldosterone; Angiotensin II; Blood Pressure; Depression, Chemical; Female; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Saralasin | 1979 |
Plasma catecholamines determination using high pressure liquid chromatography and their roles in blood pressure regulation and experimental hypertension in rats.
Topics: Aging; Anesthesia; Angiotensin II; Animals; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Circadian Rhythm; Hemorrhage; Hydroxydopamines; Hypertension; Male; Rats; Sodium | 1979 |
Sympathetic nerve activity in low renin essential hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Dopamine beta-Hydroxylase; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Posture; Renin; Sodium; Sympathetic Nervous System; Tyramine | 1979 |
Sodium-volume factor, cardiovascular reactivity and hypotensive mechanism of diuretic therapy in mild hypertension associated with diabetes mellitus.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Blood Volume; Chlorthalidone; Diabetes Complications; Diabetes Mellitus; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Placebos; Sodium | 1979 |
Blood pressure reduction by incremental infusion of labetalol in patients with severe hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Infusions, Parenteral; Labetalol; Middle Aged; Time Factors | 1979 |
Vaule of renin measurement, saralasin test, and acebutolol treatment in hypertension.
Topics: Acebutolol; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Heart Rate; Humans; Hypertension; Middle Aged; Natriuresis; Posture; Renal Veins; Renin; Saralasin | 1979 |
Angiotensins I and II in renal vein blood.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensins; Humans; Hypertension; Middle Aged; Renal Artery; Renal Artery Obstruction; Renal Veins; Renin | 1979 |
Studies on the renin-angiotensin-aldosterone system in elderly hypertensive patients with an angiotensin II antagonist.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1979 |
[Value of angiotensin II test and the "roll over test" as predictable methods of acute hypertensive disease in pregnancy (pre eclampsia and eclampsia)].
Topics: Angiotensin II; Eclampsia; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Prognosis | 1979 |
Hypertension, hyperkalaemia and abnormalities of the renin-angiotensin system in diabetes mellitus.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hyperkalemia; Hypertension; Middle Aged; Potassium; Renin | 1979 |
[Renin-angiotensin system in essential hypertension].
Topics: Angiotensin II; Angiotensin III; Animals; Dogs; Humans; Hypertension; Rabbits; Renin | 1979 |
The renin-angiotensin-aldosterone system in hypertension: its biochemistry and applications.
Topics: Adult; Age Factors; Aldosterone; Amino Acid Sequence; Angiotensin II; Angiotensins; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Kinetics; Male; Middle Aged; Renin; Saralasin; Sodium | 1979 |
Effects of acute hypotension and hypertension on serum TSH concentrations in male rats.
Topics: Acute Disease; Angiotensin II; Animals; Clonidine; Dihydralazine; Hypertension; Hypotension; Male; Nitroprusside; Norepinephrine; Rats; Sodium Chloride; Thyrotropin | 1979 |
The renin-angiotensin system and the antihypertensive effect of atenolol in man.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Atenolol; Female; Humans; Hypertension; Male; Middle Aged; Propanolamines; Renin; Saralasin | 1979 |
[Effect of saralasin infusion on glomerular filtration rate and sodium excretion in hypertensive patients (author's transl)].
Topics: Angiotensin II; Blood Pressure; Creatinine; Glomerular Filtration Rate; Humans; Hypertension; Kidney Tubules; Potassium; Saralasin; Sodium | 1979 |
[The role of prostaglandins in the renal regulation of blood pressure (author's transl)].
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Humans; Hypertension; Kidney; Natriuresis; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Rabbits; Rats; Renin; Vasodilation | 1979 |
[Hypotensive effects of diltiazem hydrochloride in the normotensive, spontaneously hypertensive and renal hypertensive rats (author's transl)].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Diltiazem; Heart Rate; Hypertension; Hypertension, Renal; Male; Norepinephrine; Rats | 1979 |
Vascular reactivity in the pathogenesis of spontaneous hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Hydroxydopamines; Hypertension; Kidney; Male; Norepinephrine; Rats; Serotonin; Sympathetic Nervous System; Vascular Resistance; Vasopressins | 1979 |
Central hypertensive actions of angiotensin I, II and III in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Injections, Intraventricular; Male; Rats | 1979 |
Differential development of salt-induced and renal hypertension in Dahl hypertension-sensitive rats after neonatal sympathectomy.
Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Constriction; Hypertension; Hypertension, Renal; Male; Norepinephrine; Pentolinium Tartrate; Rats; Renal Artery; Sympathetic Nervous System; Tyramine | 1979 |
[Physiopathological study of low renin essential hypertension].
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin; Spironolactone | 1977 |
Development of arterial hypertension in rats under combined action of exogenous stress and angiotensin II [proceedings].
Topics: Angiotensin II; Animals; Humans; Hypertension; Rats; Stress, Psychological | 1977 |
[Central A II-antagonism in experimental hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Hypertension, Renal; Injections, Intravenous; Injections, Intraventricular; Rats | 1977 |
Tubuloglomerular feedback and autoregulation of glomerular filtration rate in Wistar-Kyoto spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Glomerular Filtration Rate; Hypertension; Kidney Glomerulus; Kidney Tubules; Male; Nephrons; Rats; Renin | 1978 |
Sequential changes in the human renin-angiotensin system following delivery.
Topics: Angiotensin II; Female; Humans; Hypertension; Labor, Obstetric; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1978 |
The brain and arterial hypertension: new direction in an old relationship.
Topics: Angiotensin II; Brain; Brain Diseases; Cerebrovascular Circulation; Humans; Hypertension; Pressoreceptors | 1978 |
Influence of somatostatin on blood pressure and plasma renin activity in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Hypertension, Renal; Male; Norepinephrine; Rats; Renin; Somatostatin; Time Factors | 1978 |
Effect of an angiotensin II analogue upon blood pressure, plasma renin concentration and plasma aldosterone in hypertensive patients.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin; Time Factors | 1979 |
[Effects of (1sarcosine, 8isoleucine) angiotensin II analogue on the adrenal cortex and medullary hormones].
Topics: Adrenal Cortex Hormones; Adult; Angiotensin II; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin | 1977 |
Lowering of hypertension by central saralasin in the absence of plasma renin.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Female; Hypertension; Male; Nephrectomy; Rats; Saralasin | 1977 |
[Pathophysiology of hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Renin | 1977 |
[Plasma aldosterone concentration and vascular reactivity in hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Vessels; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Serotonin; Skin; Vasomotor System | 1977 |
[Role of prostaglandins in blood pressure regulation].
Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Blood Vessels; Diet; Epinephrine; Female; Hypertension; Indomethacin; Male; Norepinephrine; Prostaglandin Antagonists; Prostaglandins E; Rabbits; Rats; Sodium Chloride | 1977 |
[Hypertension in chronic renal insufficiency].
Topics: Angiotensin II; Humans; Hypertension; Kidney Failure, Chronic; Prostaglandins; Renin; Water-Electrolyte Imbalance | 1977 |
Effects of 1-Sar-8-Ile-angiotensin II on urinary prostaglandin excretion in patients with essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Prostaglandins E; Prostaglandins F; Renin | 1977 |
[Role of the renin-angiotensin system in arterial hypertension. Results of study of the effects of a beta blockader, sotalol].
Topics: Angiotensin II; Cardiac Output; Humans; Hypertension; Renin; Sotalol; Vascular Resistance | 1977 |
Acute changes of evoked potentials in an angiotensin-induced hypertension model [proceedings].
Topics: Angiotensin II; Animals; Evoked Potentials; Hippocampus; Hypertension; Rats; Visual Cortex | 1977 |
[Importance of the receptors of the cardio-pulmonary and aortic areas in the control of cardiac inotropism during arterial pressure elevation].
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Dogs; Heart; Hypertension; Myocardial Contraction; Pressoreceptors; Pulmonary Artery; Vagotomy; Vagus Nerve | 1977 |
Venous smooth muscle function during the development of genetic hypertension.
Topics: Angiotensin II; Animals; Hypertension; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Norepinephrine; Portal Vein; Prostaglandins; Rats; Veins | 1977 |
[The angiotensin II block in human malignant hypertension].
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension | 1977 |
[Modification of genetic hypertension in rats].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Denervation; Diet, Sodium-Restricted; Diuresis; Drinking Behavior; Feeding Behavior; Hypertension; Kidney; Natriuresis; Rats; Rats, Inbred Strains; Renal Artery Obstruction; Sodium | 1977 |
[Diagnostic and therapeutic significance of inhibitors of the renin-angiotensin system].
Topics: Angiotensin II; Animals; Dogs; Humans; Hypertension; Kinins; Oligopeptides; Pindolol; Propranolol; Renin; Saralasin; Teprotide | 1977 |
[What role does the renin-angiotensin system have in the pathogenesis of hypertension?].
Topics: Aldosterone; Angiotensin II; Animals; Corticosterone; Desoxycorticosterone; Extracellular Space; Hypertension; Hypertension, Renal; Hyponatremia; Rats; Renal Artery Obstruction; Renin; Saralasin; Sodium; Sodium Chloride; Teprotide | 1977 |
[Variable action of central and peripheral angiotensin II blockade in genetic hypertension in rats].
Topics: Angiotensin II; Animals; Desoxycorticosterone; Femoral Vein; Hypertension; Hypertension, Renal; Injections, Intravenous; Injections, Intraventricular; Rats; Rats, Inbred Strains; Saralasin | 1977 |
[Angiotensin blockade in the diagnosis of hypertension].
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Oligopeptides; Renin; Saralasin; Sodium; Teprotide | 1977 |
[Diagnostic ability of the renin-angiotensin-aldosterone-system (R.A.A.-system) stimulation as a screening test in hypertension].
Topics: Aldosterone; Angiotensin II; Diagnosis, Differential; Furosemide; Humans; Hypertension; Hypertension, Renal; Renin | 1977 |
[Hemodynamics, renin and aldosterone following angiotensin II blockade and sodium chloride deficiency in hypertensive subjects].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Diet, Sodium-Restricted; Heart Rate; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Renin; Saralasin | 1977 |
[Differential diagnosis of hypertension using the angiotensin II antagonist saralasin].
Topics: Angiotensin II; Bartter Syndrome; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Renin; Saralasin | 1977 |
Failure of renin suppression by angiotensin II in hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Depression, Chemical; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Hypertension, Renal; Male; Renin; Teprotide; Time Factors | 1978 |
Hemodynamic correlates of saralasin-induced arterial pressure changes.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Saralasin; Vascular Resistance | 1978 |
Effect of saralasin upon plasma catecholamines in hypertensive patients.
Topics: Angiotensin II; Blood Pressure; Epinephrine; Heart Rate; Humans; Hypertension; Norepinephrine; Saralasin; Stimulation, Chemical; Time Factors | 1978 |
Effect of saralasin in hypertensive patients on chronic hemodialysis.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Nephrectomy; Renal Dialysis; Renin; Saralasin | 1978 |
Radioimmunoassay for saralasin by means of anti-angiotensin II sera.
Topics: Angiotensin II; Cross Reactions; Humans; Hypertension; Immune Sera; Infusions, Parenteral; Radioimmunoassay; Saralasin | 1978 |
Angiotensin II blockade before and after marked sodium depletion in patients with hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Hyponatremia; Kidney; Male; Middle Aged; Renin; Saralasin | 1978 |
Clinical, biochemical and pathological features of low-renin ("primary") hyperaldosteronism.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aging; Angiotensin II; Angiotensinogen; Carbon Dioxide; Corticosterone; Desoxycorticosterone; Female; Humans; Hyperaldosteronism; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Potassium; Renin; Sodium; Urea; Vascular Diseases | 1978 |
Effect of parathyroidectomy on cardiovascular reactivity in rats with mineralocorticoid-induced hypertension.
Topics: Angiotensin II; Animals; Atropine; Calcium; Desoxycorticosterone; Hemodynamics; Hypertension; Male; Norepinephrine; Parathyroid Glands; Pentolinium Tartrate; Rats; Thyroidectomy; Transplantation, Autologous | 1978 |
Effect of saralasin on plasma aldosterone in hypertensive man.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Furosemide; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Potassium; Renin; Saralasin; Sodium | 1978 |
Renin, blood volume and response to saralasin in patients on chronic haemodialysis: evidence against volume- and renin-'dependent' hypertension.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Blood Volume; Diet; Female; Humans; Hypertension; Male; Middle Aged; Renal Dialysis; Renin; Saralasin; Sodium | 1978 |
[Anti-hypertensive effect of the angiotensin II antagonist saralasin acetate, a diagnostic criterion of renovascular hypertension].
Topics: Angiotensin II; Humans; Hypertension; Hypertension, Renal; Saralasin | 1978 |
Pressor response to saralasin (1-sar-8-ala-angiotensin II) bolus injection in hypertensive patients.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Child; Female; Humans; Hypertension; Male; Middle Aged; Pressoreceptors; Renin; Saralasin; Sodium; Time Factors | 1978 |
The effect of an angiotensin antagonist (saralasin) on arterial pressure and plasma aldosterone in hemodialysis-resistant hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Filtration; Humans; Hypertension; Male; Middle Aged; Renal Dialysis; Renin; Saralasin | 1978 |
Sodium depletion and blood pressure response to 1-sarcosine, 8-isoleucine angiotensin II in hypertension.
Topics: Angiotensin II; Blood Pressure; Diet; Furosemide; Humans; Hypertension; Renin; Sodium | 1978 |
[Clinical usefulness of saralasin in human hypertension (author's transl)].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Renal Artery Obstruction; Renin; Saralasin | 1978 |
Hypotensive effect of [Sar1,Thr8]angiotensin II in spontaneously hypertensive sodium-depleted rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Diet, Sodium-Restricted; Hypertension; Infusions, Parenteral; Rats; Renin; Saralasin; Sodium | 1978 |
Effects of central and peripheral angiotensin blockade in hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Female; Hypertension; Hypertension, Renal; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Renin; Saralasin | 1978 |
Renin angiotensin involvement in transient hypertension after renal injury.
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hypertension; Kidney; Male; Nitroprusside; Renin; Saralasin; Wounds, Nonpenetrating | 1978 |
Mechanism of blood pressure reduction by teprotide (SQ 20881) in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Drug Interactions; Female; Hypertension; Nephrectomy; Oligopeptides; Rats; Saralasin; Sodium Chloride; Teprotide | 1978 |
Pressor response to saralasin reversed by phentolamine in essential hypertension.
Topics: Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Middle Aged; Phentolamine; Saralasin | 1978 |
Relative significance of plasma renin activity and concentration in physiologic and pathophysiologic conditions.
Topics: Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Diet; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Physical Exertion; Renal Artery Obstruction; Renal Veins; Renin; Saralasin | 1978 |
Arterial compliance in permanent essential hypertension: preliminary report.
Topics: Adult; Age Factors; Angiotensin II; Arteries; Blood Pressure; Compliance; Hemodynamics; Humans; Hypertension; Male; Mathematics; Nitroprusside | 1978 |
Whole body vascular reactivity during the development of deoxycorticosterone acetate hypertension in the pig.
Topics: Angiotensin II; Animals; Blood Circulation; Blood Pressure; Desoxycorticosterone; Hypertension; Male; Norepinephrine; Swine; Vascular Resistance | 1978 |
The pressor response to angiotensin II in patients with low renin essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Urea Nitrogen; Humans; Hyperaldosteronism; Hypertension; Potassium; Pressoreceptors; Renin; Sodium | 1978 |
Increased adrenal sensitivity to angiotensin II in low-renin essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Male; Metabolic Clearance Rate; Middle Aged; Posture; Renin | 1978 |
Serum uric acid and the renin-angiotensin system in hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin II; Child; Creatinine; Extracellular Space; Female; Furosemide; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Middle Aged; Renin; Uric Acid | 1978 |
[Action of beta blockaders in hypertension caused by isthmic aortic coarctation: a new proof in favor of renin-angiotensin system].
Topics: Acebutolol; Adolescent; Adult; Angiotensin II; Aortic Coarctation; Child; Female; Humans; Hypertension; Male; Renin | 1978 |
Frontiers in the therapy of hypertension.
Topics: Angiotensin II; Blood Vessels; Humans; Hypertension; Patient Compliance; Renin; Sympathetic Nervous System; Water-Electrolyte Balance | 1978 |
Physiologic determinants and clinical applications of angiotensin II blockade in hypertensive disorders.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Saralasin | 1978 |
[Experimental hypertensions].
Topics: Angiotensin II; Animals; Blood Vessels; Cats; Central Nervous System; Denervation; Desoxycorticosterone; Disease Models, Animal; Dogs; Heart; Hypertension; Kidney; Pressoreceptors; Rats; Renin; Sodium Chloride; Sympathetic Nervous System; Water-Electrolyte Balance | 1978 |
Comparison of the biological effects of two angiotensin II analogues in hypertensive patients with sodium depletion.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Renin; Saralasin | 1978 |
Hypertension and oral contraceptives.
Topics: Adult; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Renin | 1978 |
Failure of chronic aldosterone infusion to increase arterial pressure in dogs with angiotensin-induced hypertension.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Computers; Dogs; Hematocrit; Hypertension; Male; Methylprednisolone; Natriuresis; Potassium; Radioimmunoassay; Renin; Sodium | 1978 |
Sephadex globules placed as landmarks in combined stereo microscopy, scanning and transmission electron microscopy.
Topics: Angiotensin II; Animals; Arteries; Arterioles; Coronary Vessels; Dextrans; Hypertension; Intestine, Small; Kidney; Liver; Microscopy, Electron; Microscopy, Electron, Scanning; Papillary Muscles; Rats; Spleen | 1978 |
[Effect of saralasin on plasma renin activity and arginine-vasopressin in patients with angiotensin-dependent hypertension (author's transl)].
Topics: Adolescent; Adult; Angiotensin II; Arginine Vasopressin; Female; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin; Stimulation, Chemical; Vasopressins | 1978 |
Use of supine pressor test to prevent gestational hypertension in primigravid women.
Topics: Adult; Angiotensin II; Blood Pressure Determination; Eclampsia; Female; Humans; Hypertension; Infant, Newborn; Posture; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular | 1978 |
SQ 20,881: effect on eclamptic--pre-eclamptic women with postpartum hypertension.
Topics: Adolescent; Adult; Angiotensin II; Eclampsia; Female; Furosemide; Hemodynamics; Humans; Hypertension; Oligopeptides; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Puerperal Disorders; Renin; Teprotide | 1978 |
Subpressor angiotensin infusion, renal sodium handling, and salt-induced hypertension in the dog.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Furosemide; Hypertension; Infusions, Parenteral; Natriuresis; Renin; Sodium Chloride; Spironolactone; Time Factors | 1978 |
[Clinical application of angiotensin II derivatives].
Topics: Adrenal Gland Diseases; Adult; Angiotensin II; Angiotensin III; Humans; Hypertension; Hypertension, Renal; Male | 1978 |
Effects of 1-sar-8-ala-angiotensin II on arterial pressure, renin and aldosterone in hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet; Female; Humans; Hypertension; Male; Renin; Saralasin; Sodium | 1978 |
What makes the renin-angiotensin system a pathogenic factor?
Topics: Angiotensin II; Animals; Blood Pressure; Corticosterone; Hypertension; Hypertension, Renal; Kidney; Male; Rats; Renal Artery Obstruction; Renin; Sodium | 1978 |
Role of renin and aldosterone suppression in the antihypertensive mechanism of clonidine.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin | 1978 |
[Saralasin for renovascular or essential hypertension (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hypertension, Renal; Kidney; Male; Middle Aged; Receptors, Angiotensin; Renal Artery Obstruction; Renin; Saralasin | 1978 |
[Studies of urinary kallikrein in patients with various types of hypertension (relationship to renin-angiotension-aldosterone system (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kallikreins; Kidney Diseases; Male; Middle Aged; Radioimmunoassay; Renin | 1978 |
[Effects of sodium depletion on renal action of 1-sarcosine-8-isoleucine-angiotensin II in patients with essential hypertension (author's transl)].
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertension; Kidney; Male; Middle Aged | 1978 |
[Saralasin-induced changes of blood pressure, renin and aldosterone in essential and renal hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Renin; Saralasin | 1978 |
Increased renal vascular reactivity to norepinephrine in stroke-prone spontaneously hypertensive rat (SHR).
Topics: Angiotensin II; Animals; Cerebrovascular Disorders; Hypertension; In Vitro Techniques; Kidney; Male; Norepinephrine; Potassium Chloride; Rats; Regional Blood Flow; Vasoconstriction | 1978 |
Renin subgroups in essential hypertension: an analysis and critique.
Topics: Angiotensin II; Bendroflumethiazide; Humans; Hypertension; Middle Aged; Renin; Sodium | 1978 |
Blood pressure, renin-angiotensin system and urinary kallikrein in a case of juxtaglomerular cell tumor.
Topics: Acebutolol; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Half-Life; Humans; Hypertension; Kallikreins; Kidney Neoplasms; Renin; Saralasin | 1978 |
Pregnancy hypertension, parity, and the renin-angiotensin system.
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Parity; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Renin; Time Factors | 1978 |
[Diagnostic and therapeutic significance of antagonists of the renin-angiotensin system (author's transl)].
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Humans; Hypertension; Oligopeptides; Propranolol; Saralasin; Teprotide | 1978 |
[Vascular reactivity and catecholamine excretion in hypertension].
Topics: Adult; Angiotensin II; Catecholamines; Ephedrine; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Vascular Resistance | 1978 |
Systemic and pulmonary hemodynamic effects of saralasin infusion in hypertension. Predictability of plasma renin status from hemodynamic changes.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Cardiac Output; Evaluation Studies as Topic; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Pulmonary Circulation; Renin; Saralasin; Vascular Resistance | 1978 |
Renin-angiotensin system in severe hypertension of stroke-prone SHR rats.
Topics: Angiotensin II; Animals; Cerebrovascular Disorders; Hypertension; Male; Rats; Renin; Sodium Chloride | 1978 |
[Responses of renin-angiotensin-aldosterone system to insulin hypoglycemia in patients with essential hypertension (author's transl)].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypoglycemia; Insulin; Male; Middle Aged; Renin | 1978 |
Increased blood pressure responses to central angiotensin II in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Injections, Intraventricular; Propranolol; Rats; Sympathetic Nervous System | 1978 |
Neurohypophyseal vasopressor principle: vasopressor hormone as well as antidiuretic hormone?
Topics: Acute Kidney Injury; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Hypertension; Hypertension, Renal; Immune Sera; Injections, Intraventricular; Radioimmunoassay; Rats; Vasopressins | 1978 |
Emergency treatment of severe hypertension with intravenous labetalol.
Topics: Adult; Aged; Angiotensin II; Emergencies; Ethanolamines; Female; Humans; Hypertension; Infusions, Parenteral; Labetalol; Male; Middle Aged; Pulse; Renin | 1978 |
The effect of the converting enzyme inhibitor SQ 20.881 on kinins, renin-angiotensin-aldosterone and catecholamines in relation to blood pressure in hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Catecholamines; Epinephrine; Female; Humans; Hypertension; Kinins; Male; Middle Aged; Norepinephrine; Oligopeptides; Posture; Renin; Teprotide | 1978 |
Essential hypertension: new concepts in diagnosis and treatment.
Topics: Angiotensin II; Extracellular Space; Humans; Hypertension; Middle Aged; Propranolol; Renin; Saralasin; Sodium; Vasoconstriction | 1978 |
Effect of saralasin on plasma renin activity and arginine-vasopressin in hypertensive man.
Topics: Adolescent; Adult; Angiotensin II; Arginine Vasopressin; Female; Humans; Hypertension; Hypertension, Renovascular; Male; Middle Aged; Receptors, Angiotensin; Renin; Saralasin | 1978 |
[Prognostic and therapeutic implications of plasma renin activity in essential arterial hypertension].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Prognosis; Renin | 1978 |
Comparison of two angiotensin II analogues in normal subjects and hypertensive patients.
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Sodium | 1978 |
[Total body potassium in low renin essential hypertension with reference to the renin-angiotensin-aldosterone system (author's transl)].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Plasma Volume; Potassium; Renin | 1978 |
[Studies on renal prostaglandin E in essential hypertension: relationships among urinary prostaglandin E, sodium balance, renin-angiotensin-aldosterone system and renal kallikrein-kinin system (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kallikreins; Kidney; Male; Prostaglandins E; Renin; Sodium | 1978 |
Comparison of the tachyphylaxis to 5-hydroxytryptamine and angiotensin-II in the isolated perfused kidney of the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; In Vitro Techniques; Kidney; Perfusion; Rats; Serotonin; Tachyphylaxis | 1978 |
Prostaglandin-mediated hyperemia and renin-mediated hypertension during acute ureteral obstruction.
Topics: Acute Disease; Angiotensin II; Animals; Dogs; Female; Hyperemia; Hypertension; Indomethacin; Kidney; Male; Meclofenamic Acid; Prostaglandins; Renin; Ureter; Ureteral Obstruction | 1978 |
Evidence for an angiotensinogenic mechanism of the hypertension of Cushing's syndrome.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Cushing Syndrome; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Renin; Saralasin | 1978 |
The immediate pressor effect of saralasin in man.
Topics: Angiotensin II; Blood Pressure; Dopamine beta-Hydroxylase; Humans; Hypertension; Norepinephrine; Renin; Saralasin | 1978 |
Saralasin testing for renin-dependent hypertension.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renovascular; Renin; Saralasin; Sodium | 1979 |
Renin-angiotensin-aldosterone system in long-term renal transplant patients.
Topics: Adult; Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Dogs; Follow-Up Studies; Humans; Hypertension; Kidney; Kidney Transplantation; Middle Aged; Potassium; Renin; Sheep; Sodium; Time Factors; Transplantation, Homologous | 1976 |
Possible contributions of endogenous prostaglandins to the control of blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Cyclooxygenase Inhibitors; Homeostasis; Hyperemia; Hypertension; Indomethacin; Kidney; Norepinephrine; Prostaglandins; Prostaglandins A; Prostaglandins F; Radioimmunoassay; Regional Blood Flow; Renin; Sympathetic Nervous System; Water-Electrolyte Balance; Wounds and Injuries | 1975 |
A circulating renin activator in essential hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Contraceptives, Oral; Diuretics; Enzyme Activation; Functional Laterality; Haplorhini; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Kinetics; Renal Artery Obstruction; Renin; Sodium; Spironolactone | 1975 |
[Equilibration of the treatment of severe arterial hypertension. Significance of d-1 propranolol].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Heart Rate; Humans; Hydralazine; Hypertension; Long-Term Care; Propranolol; Pulse; Renin | 1975 |
Evidence for enhanced venous smooth muscle turnover of prostaglandin-like substance in portal veins from spontaneously hypertensive rats.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Arachidonic Acids; Drug Interactions; Hypertension; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Portal Vein; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred Strains | 1976 |
Renin-angiotensin-aldosterone system in diabetes mellitus.
Topics: Aldosterone; Angiotensin II; Animals; Blood Volume; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Diabetic Nephropathies; Diabetic Neuropathies; Humans; Hypertension; Hypotension, Orthostatic; Juxtaglomerular Apparatus; Models, Biological; Potassium; Rats; Renin; Sodium; Vascular Resistance; Water-Electrolyte Balance | 1976 |
Depressor effect of saralasin in hypertensive crisis due to pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Blood Pressure; Depression, Chemical; Humans; Hypertension; Pheochromocytoma; Saralasin | 1977 |
A prospective study of angiotensin II pressor responsiveness in pregnancies complicated by chronic essential hypertension.
Topics: Angiotensin II; Chronic Disease; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Prognosis; Prospective Studies; Vasomotor System | 1977 |
Vascular reactivity of perfused vascular bed in spontaneously hypertensive and normotensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Hindlimb; Hypertension; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred Strains; Vasoconstrictor Agents | 1977 |
Angiotensin II in essential hypertension.
Topics: Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged | 1977 |
Pressor response to 1-sar-8-ala-angiotensin II (saralasin) in hypertensive subjects.
Topics: Adult; Angiotensin II; Blood Pressure; Blood Urea Nitrogen; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Regional Blood Flow; Renin; Saralasin; Sodium | 1977 |
Oral contraceptives and high blood pressure: a review.
Topics: Angiotensin II; Blood Pressure; Cardiac Output; Contraceptives, Oral; Estradiol Congeners; Female; Humans; Hypertension; Renin; Risk; Stimulation, Chemical | 1977 |
Cerebral cortical changes in acute experimental hypertension: An ultrastructural study.
Topics: Acute Disease; Angiotensin II; Animals; Brain Edema; Cerebral Cortex; Diffusion; Female; Horseradish Peroxidase; Hypertension; Rats; Trypan Blue | 1977 |
Reversal of hypertension by transplants and lipid extracts of cultured renomedullary interstitial cells.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Hypertension; Kidney; Kidney Medulla; Lipids; Nephrectomy; Prostaglandins; Rats | 1977 |
A pressor response associated with drinking in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Drinking; Heart Rate; Hypertension; Injections, Intraventricular; Male; Phentolamine; Posture; Rats | 1977 |
Vasopressor role of ADH in the pathogenesis of malignant DOC hypertension.
Topics: Angiotensin II; Animals; Antibodies; Arginine Vasopressin; Blood Pressure; Body Weight; Desoxycorticosterone; Diabetes Insipidus; Hypertension; Hypertension, Malignant; Immune Sera; Male; Nephrectomy; Osmolar Concentration; Rats; Renin; Sodium; Urea; Vasomotor System; Vasopressins | 1977 |
Angiotensin blockade in hypertension.
Topics: Angiotensin II; Hypertension; Posture; Renin; Saralasin; Sodium; Teprotide | 1977 |
Chronic one-kidney hypertension in rabbits. III. Renopressin, a new hypertensive substance.
Topics: Angiotensin II; Animals; Blood Pressure; Constriction; Hypertension; Kidney Cortex; Male; Nephrectomy; Rabbits; Renal Artery; Renin; Serum Globulins; Swine; Tissue Extracts | 1977 |
Blood pressure response of nephrectomized hypertensive rats to converting enzyme inhibition: evidence for persistent vascular renin activity.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Female; Hypertension; Ischemia; Kidney; Nephrectomy; Oligopeptides; Rats; Renin; Saralasin; Teprotide | 1977 |
[Esteroproteinases in the pathophysiology of hypertension].
Topics: Angiotensin II; Blood Coagulation Factors; Humans; Hypertension; Kallikreins; Peptide Hydrolases; Renin | 1977 |
Does low plasma renin activity indicate a favorable prognosis in hypertension?
Topics: Angiotensin II; Animals; Coronary Disease; Follow-Up Studies; Humans; Hypertension; Natriuresis; Prognosis; Renin | 1977 |
Antihypertensive and renin angiotensin effects of metolazone with and without propranolol.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Metolazone; Potassium; Propranolol; Renin; Sodium; Time Factors | 1977 |
Central angiotensin II-induced responses in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Diuresis; Dose-Response Relationship, Drug; Drinking; Heart Rate; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Vasopressins | 1977 |
The physiology of blood pressure regulation--normal and abnormal.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cardiac Output; Child; Glomerular Filtration Rate; Hemodynamics; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Paraneoplastic Endocrine Syndromes; Renal Artery Obstruction; Renin; Sodium; Vascular Resistance | 1977 |
Production of sustained hypertension by chronic intrarenal norepinephrine infusion in conscious dogs.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension; Kidney; Kidney Function Tests; Natriuresis; Norepinephrine; Phentolamine; Renin; Saralasin | 1977 |
Intraventricular infusion of angiotensin II on the hemodynamics and renal function of alpha-chloralose anesthetized cats.
Topics: Anesthesia, General; Angiotensin II; Animals; Cats; Chloralose; Diuresis; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension; Infusions, Parenteral; Injections, Intraventricular; Kidney Function Tests; Male; Natriuresis; Vascular Resistance | 1977 |
Aldosterone regulation in essential hypertension: altered adrenal responsiveness to angiotensin II.
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Infusions, Parenteral; Male; Posture; Renin; Sodium Chloride | 1977 |
Altered renin-angiotensin-aldosterone relationships in normal renin essential hypertension.
Topics: Adrenal Cortex; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Kidney; Male; Potassium; Renin; Sodium | 1977 |
The effects of propranolol on acute hypertension of anesthetized dogs and on the carotid sinus reflex responses of anesthetized and awake dogs.
Topics: Acute Disease; Angiotensin II; Animals; Blood Pressure; Carotid Artery, External; Carotid Sinus; Denervation; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Hypothalamus, Middle; Male; Myocardial Contraction; Norepinephrine; Propranolol; Vagotomy | 1977 |
Plasma renin and angiotensin II measurement in hypertensive and normal subjects: correlation of basal and stimulated states.
Topics: Adult; Angiotensin II; Bendroflumethiazide; Diazoxide; Female; Humans; Hypertension; Male; Middle Aged; Reference Values; Renin | 1977 |
Saralasin infusion in the recognition of renovascular hypertension.
Topics: Angiotensin II; Blood Pressure; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Nephrectomy; Renal Artery Obstruction; Renin; Saralasin | 1977 |
[The value of stimulation of the renin-angiotensin-aldosterone system as a screening test for hypertension (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Diuretics; Furosemide; Humans; Hypertension; Male; Middle Aged; Pyrazoles; Renin; Veins | 1977 |
Aids in the diagnosis of hypertension.
Topics: Aldosterone; Angiotensin II; Cardiovascular Diseases; Diuretics; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Renin | 1977 |
Role of renin-angiotensin system in experimental hypertension in rats: plasma renin and hypotensive effect of angiotensin II antagonist.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Female; Furosemide; Hypertension; Hypertension, Renal; Rats; Rats, Inbred Strains; Renin; Saralasin; Species Specificity | 1977 |
Clinical evaluation of angiotensin II antagonist in advanced hypertension.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin | 1977 |
Brain energy metabolism in angiotensin-induced acute hypertension in rats.
Topics: Acute Disease; Ammonia; Angiotensin II; Animals; Blood-Brain Barrier; Brain; Energy Metabolism; Glucose; Glycogen; Hypertension; Ischemic Attack, Transient; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains | 1977 |
Prospective study of angiotensin II response to positional change in pregnancy-induced hypertension.
Topics: Angiotensin II; Female; Homeostasis; Humans; Hypertension; Placenta; Posture; Pregnancy; Pregnancy Complications, Cardiovascular; Prospective Studies; Time Factors; Uterus | 1977 |
Renin, sodium, and vasodepressor response to saralasin in renovascular and essential hypertension.
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Prospective Studies; Renin; Saralasin; Sodium; Vasomotor System | 1977 |
Diuretic therapy and response of essential hypertension to saralasin.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Saralasin; Spironolactone; Stimulation, Chemical | 1977 |
Amiloride in the treatment of primary hyperaldosteronism and essential hypertension.
Topics: Adult; Aged; Amiloride; Angiotensin II; Electrolytes; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Pyrazines; Renin | 1977 |
The role of the kidney in hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diuresis; Humans; Hypertension; Kidney; Natriuresis; Rats; Renin; Water-Electrolyte Imbalance | 1977 |
[Stimulation of renin-angiotensin-aldosterone system as screening test for hypertension].
Topics: Aldosterone; Angiotensin II; Furosemide; Humans; Hypertension; Methods; Propranolol; Renin | 1977 |
[Critical analysis of the saralasintest in the diagnosis of hypertension (author's transl)].
Topics: Angiotensin II; Blood Pressure; Diagnosis, Differential; Evaluation Studies as Topic; Female; Humans; Hypertension; Hypertension, Renal; Male; Renin; Saralasin | 1977 |
Brain and kidney renin-angiotensin activity in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Brain Stem; Cerebral Cortex; Disease Models, Animal; Female; Hypertension; Kidney; Male; Medulla Oblongata; Rats; Renin; Rodent Diseases | 1977 |
Hypotensive effects of sodium volume depletion and 1-sar-8-ala-angiotensin II in relation to plasma renin in hypertensive patients.
Topics: Adult; Angiotensin II; Blood Pressure; Body Weight; Chlorthalidone; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Renin; Saralasin; Sodium | 1977 |
[The renin-angiotensin system in arterial hypertension].
Topics: Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Renin | 1977 |
A simple test for predicting pregnancy-induced hypertension.
Topics: Angiotensin II; Blood Pressure Determination; Female; Humans; Hypertension; Infant, Newborn; Male; Posture; Pregnancy; Pregnancy Complications, Cardiovascular | 1977 |
Neural regulation of renin release: experimental evidence and clinical implications in arterial hypertension.
Topics: Adrenergic Fibers; Angiotensin II; Animals; Hemodynamics; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Pressoreceptors; Propranolol; Reflex; Renin; Vagotomy; Vagus Nerve | 1977 |
Plasma catecholamines and the pressor response to Sar1-Ala8-angiotensin II in man.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Blood Volume; Catecholamines; Extracellular Space; Female; Humans; Hypertension; Male; Middle Aged; Renal Dialysis; Renin; Saralasin | 1977 |
[Effects of an analogue of angiotensin II, [Sar1,Ile8] ATII, on blood pressure, plasma renin activity and plasma aldosterone in various forms of hypertension].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hypertension, Renal; Infusions, Parenteral; Male; Middle Aged; Renin | 1977 |
[Effects of acute sodium depletion on blood pressure and renin-angiotensin-aldosterone system in patients with benign essential hypertension (author's transl)].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Electrolytes; Female; Hematocrit; Humans; Hypertension; Male; Middle Aged; Renin; Sodium | 1977 |
Inappropriate secretion of antiduretic hormone, hypertension, and hypoplastic corpus callosum.
Topics: Adolescent; Agenesis of Corpus Callosum; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pressure; Female; Humans; Hypertension; Osmolar Concentration; Renin; Sodium Chloride; Syndrome; Vasopressins; Water-Electrolyte Balance | 1977 |
Increased permeability for plasma components of the cerebral vessels during acute angiotensin hypertension in rats.
Topics: Angiotensin II; Animals; Arterioles; Blood Proteins; Brain; Capillary Permeability; Carbon; Colloids; Female; Hypertension; Rats; Veins; Venules | 1977 |
Vascular reactivity of isolated perfused kidneys from male and female spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Barium; Blood Circulation; Blood Pressure; Chlorides; Cocaine; Dose-Response Relationship, Drug; Female; Guanethidine; Hydroxydopamines; Hypertension; Kidney; Male; Norepinephrine; Perfusion; Phentolamine; Rats; Reserpine; Serotonin; Time Factors | 1977 |
[A clinical study on an antagonist of angiotensin II. Application to diagnosis and pharmacological treatment (author's transl)].
Topics: Adolescent; Adult; Angiotensin II; Antihypertensive Agents; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1977 |
[Significance of renin-angiotensin system inhibitors in the diagnosis of hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dogs; Enzyme Inhibitors; Humans; Hypertension; Pindolol; Propranolol; Rats; Renal Artery Obstruction; Renin; Saralasin | 1977 |
[The renin-angiotensin-aldosterone system in essential arterial hypertension].
Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Kidney; Male; Middle Aged; Posture; Renin; Stimulation, Chemical | 1977 |
[The effects of clonidine on the renin-angiotensin-aldosterone system in patients with hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Clonidine; Drug Evaluation; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Renin; Stimulation, Chemical | 1977 |
[Plasma renin activity and vascular reactivity to vasoactive substances in hypertensive patients].
Topics: Adult; Angiotensin II; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Serotonin | 1977 |
Effect of angiotensin-induced hypertension on rat coronary arteries and myocardium.
Topics: Angiotensin II; Animals; Cell Membrane Permeability; Coronary Circulation; Coronary Vessels; Horseradish Peroxidase; Hypertension; Male; Microscopy, Electron; Myocardium; Rats | 1976 |
Proceedings: Relationship between cathecholamine and renin-angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Rats; Renin | 1976 |
[Method of quantitative evaluation of the reactivity of the microvessels to vasoactive substances in patients with hypertensive disease].
Topics: Angiotensin II; Capillaries; Capillary Permeability; Hemodynamics; Humans; Hypertension; Methods; Norepinephrine; Serotonin; Skin; Sodium Radioisotopes | 1976 |
The hypertension of long-term hemodialysis patients: studies with an angiotensin II antagonist (P113).
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nephrectomy; Renal Dialysis; Renin; Saralasin | 1976 |
Changes in the renin-angiotensin system in normotensive and hypertensive women during pregnancy and parturition.
Topics: Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Labor, Obstetric; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, First; Renin | 1976 |
Oral contraceptives--induced hypertension--nine years later.
Topics: Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Renin | 1976 |
Plasma renin and the antihypertensive effect of angiotensin-II antagonist in experimental hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Female; Hypertension; Male; Rats; Renin | 1976 |
Hypotensive response to angiotensin II analogue in benign essential hypertension.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Female; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Sodium; Sympathetic Nervous System | 1976 |
[Angiotensin-induced hypertension in pigs].
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Myocardium; Swine | 1976 |
A delayed suppression of the renin-aldosterone axis following saline infusion in human hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Female; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Potassium; Renin; Sodium; Sodium Chloride; Time Factors | 1976 |
Clinical pharmacology of angiotensin antagonists.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Humans; Hypertension; Radioimmunoassay; Receptors, Angiotensin; Renin; Saralasin; Time Factors | 1976 |
The effect of saralasin (1sar-8-ala-angiotensin II) on blood pressure in patients with Cushing's syndrome.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Cushing Syndrome; Female; Humans; Hyperaldosteronism; Hypertension; Renin; Saralasin | 1976 |
[Renin-angiotensin system in the diagnosis of essential hypertension].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1976 |
[The renin-angiotensin system in normal and hypertensive individuals].
Topics: Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Renin | 1976 |
A role for renin in rebound hypertension and encephalopathy after infusion of saralasin acetate (Sar1-Ala8-angiotensin II).
Topics: Angiotensin II; Blood Pressure; Female; Headache; Humans; Hypertension; Male; Middle Aged; Propranolol; Renin; Saralasin; Sodium | 1976 |
Reciprocal relation between renin dependency and sodium dependency in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Feedback; Humans; Hypertension; Kidney; Middle Aged; Renin; Saralasin; Secretory Rate; Sodium | 1976 |
[A critical review of hypothetical causes of EPH-gestosis].
Topics: Aldosterone; Angiotensin II; Animals; Biogenic Amines; Blood Volume; Body Fluids; Edema; Female; Fibrin Fibrinogen Degradation Products; Hormones; Humans; Hypertension; Immunity; Kidney Diseases; Nutritional Physiological Phenomena; Placenta; Pre-Eclampsia; Pregnancy; Prostaglandins; Proteinuria; Renin; Uterus; Vasoconstrictor Agents | 1976 |
Renin-angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Female; Hypertension; Kidney; Male; Rats; Rats, Inbred Strains; Renin; Submandibular Gland | 1976 |
[Causative factors in hypertension].
Topics: Angiotensin II; Catecholamines; Glucocorticoids; Hypertension; Mineralocorticoids; Renin | 1976 |
[Clinical application of an angiotensin II analogue (ii). Blood pressure changes following the infusion of 1-sarcosine. 8-isoleucine angiotensin II in various hypertensive disorders and body fluid abnormalities (author's transl)].
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Body Fluids; Female; Humans; Hypertension; Male; Middle Aged | 1976 |
[The experimental examination of the effect on the uterine blood flow of angiotensin II during pregnancy (author's transl)].
Topics: Angiotensin II; Animals; Epinephrine; Female; Hypertension; Kidney; Kidney Cortex; Norepinephrine; Pregnancy; Pregnancy Complications, Cardiovascular; Rabbits; Regional Blood Flow; Uterus | 1976 |
Prostaglandin E2 released from the kidneys of genetic hypertensive rats contributes to the vasoconstrictor supersensitivity to angiotensin II in vitro [proceedings].
Topics: Angiotensin II; Animals; Arachidonic Acids; Hypertension; In Vitro Techniques; Kidney; Male; Prostaglandins E; Rats; Vasoconstrictor Agents | 1976 |
Hypotension during angiotensin blockade with saralasin.
Topics: Adult; Angiotensin II; Chlorthalidone; Humans; Hypertension; Hypotension; Male; Saralasin | 1976 |
[Study of plasma renin activity in 40 subjects submitted to periodic hemodialysis].
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Body Weight; Child; Female; Humans; Hypertension; Male; Middle Aged; Renal Dialysis; Renin | 1976 |
[Evaluation of plasma remin activity and urinary excretion of aldosterone in subjects with clinically essential hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1976 |
[Sodium, hypertension and diuretics].
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Diuretics; Humans; Hypertension; Renin; Sodium; Sodium Chloride Symporter Inhibitors | 1976 |
Penetration of fluorescent homologous serum proteins into the wall of the aorta in rats with acute angiotensin hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Aorta; Blood Proteins; Female; Fluorescence; Hypertension; Rats | 1976 |
The clinical effect of acute blood pressure increase in conscious rats. A comparison between normotensive and spontaneously hypertensive rats.
Topics: Acute Disease; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Blood-Brain Barrier; Consciousness; Dihydralazine; Hypertension; Male; Rats; Seizures | 1976 |
Left ventricular function during acute elevation of aortic blood pressure in dogs.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blood Volume; Cardiac Output; Constriction; Constriction, Pathologic; Dogs; Female; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Hypertension; Isoproterenol; Male; Myocardial Contraction | 1976 |
Vascular reactivity in the isolated perfused kidney of the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Barium; Electric Stimulation; Hypertension; Kidney; Norepinephrine; Rats; Regional Blood Flow; Serotonin; Vascular Resistance | 1976 |
Angiotensin II blockade with saralasin.
Topics: Angiotensin II; Female; Humans; Hypertension; Hypotension; Saralasin; Water-Electrolyte Imbalance | 1976 |
Quantification of baroreceptor influence on arterial pressure changes seen in primary angiotension-induced hypertension in dogs.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blood Volume; Cardiac Output; Carotid Sinus; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Pressoreceptors; Sodium; Stimulation, Chemical; Time Factors | 1976 |
Acute and chronic dose-response relationships for angiotensin, aldosterone, and arterial pressure at varying levels of sodium intake.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Diet; Dogs; Dose-Response Relationship, Drug; Hypernatremia; Hypertension; Hyponatremia; Potassium; Sodium; Time Factors | 1976 |
Studies of the renin-angiotension-aldosterone system, cortisol, DOC, and ADH in normal and hypertensive pregnancy.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Angiotensinogen; Arginine Vasopressin; Corticosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hypertension; Ovulation; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, First; Renin; Sodium; Vasopressins | 1976 |
Sequential changes in the renin--angiotensin--aldosterone systems and plasma progesterone concentration in normal and abnormal human pregnancy.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Renin | 1976 |
[Endocrine disorders in patients with essential hypertension].
Topics: Aldosterone; Angiotensin II; Catecholamines; Humans; Hypertension; Prostaglandins; Renin | 1976 |
Hypertension in adult rats treated neonatally with angiotensin.
Topics: Angiotensin II; Animals; Animals, Newborn; Brain; Female; Hypertension; Male; Rats; Renin | 1976 |
[Results of radioimmunologic determination of renin activity and the concentration of angiotensin II in the plasma of hypertensive patients].
Topics: Adolescent; Adult; Age Factors; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Pulse; Radioimmunoassay; Renin; Time Factors | 1976 |
Renin and angiotensin in hypertension.
Topics: Angiotensin II; Humans; Hypertension; Kidney; Renin | 1976 |
[Angiotensin II inhibitors for the diagnosis and treatment of hypertension].
Topics: Adult; Angiotensin II; Animals; Humans; Hypertension; Hypertension, Renal; Male; Oligopeptides; Rats; Renin; Saralasin; Sodium; Teprotide | 1976 |
[Studies on the blood pressure effects of various high doses of angiotensin II in depot form in rats under defined conditions].
Topics: Angiotensin II; Animals; Delayed-Action Preparations; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Rats | 1976 |
[Relationship between renin-aldosterone system and efficacy of a beta-blocking agent in hypertensive patients].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Posture; Propranolol; Renin | 1976 |
The use of saralasin to evaluate the function of the brain renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Dogs; Drinking; Hypertension; Rats; Renin; Saralasin; Swine; Vasopressins | 1976 |
Angiotensin II blockade in normal man and patients with essential hypertension. Blood pressure effects depending on renin and sodium balance.
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Saralasin; Sodium; Time Factors | 1976 |
Changes of blood pressure, plasma renin activity and plasma aldosterone concentration following the infusion of Sar1-Ile8-angiotensin II in hypertensive, fluid and electrolyte disorders.
Topics: Acidosis, Renal Tubular; Aldosterone; Angiotensin II; Bartter Syndrome; Blood Pressure; Cushing Syndrome; Edema; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney Failure, Chronic; Liver Cirrhosis; Nephrotic Syndrome; Pheochromocytoma; Renin; Sodium; Time Factors; Water-Electrolyte Imbalance | 1976 |
Angiotensin II blockade in hypertensive dialysis patients.
Topics: Adult; Angiotensin II; Blood Pressure; Body Weight; Female; Humans; Hypertension; Male; Renal Dialysis; Renin; Saralasin; Time Factors | 1976 |
The use of saralasin in the recognition of angiotensinogenic hypertension.
Topics: Adult; Angiotensin II; Animals; Blood Pressure; Cushing Syndrome; Drug Administration Schedule; Humans; Hypertension; Kidney; Male; Rats; Renal Artery Obstruction; Renal Veins; Renin; Saralasin; Sodium | 1976 |
The effects of the angiotensin II antagonist saralasin on blood pressure and plasma aldosterone in man in relation to the prevailing plasma angiotensin II concentration.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Diet; Humans; Hyperaldosteronism; Hypertension; Kidney Failure, Chronic; Male; Renal Artery Obstruction; Renin; Saralasin; Sodium; Time Factors | 1976 |
[Reactivity of isolated arteries from hypertensive rabbits].
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arteries; Female; Femoral Artery; Histamine; Hypertension; Male; Norepinephrine; Pulmonary Artery; Rabbits; Renal Artery; Serotonin | 1976 |
Angiotensin blockade: its clinical significance.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Furosemide; Humans; Hypertension; Hypertension, Malignant; Rabbits; Renin; Saralasin; Sodium | 1976 |
Usefulness and limitations of saralasin, a partial competitive agonist of angioten II, for evaluating the renin and sodium factors in hypertensive patients.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Saralasin; Sodium | 1976 |
[Activity of blood plasma renin and angiotensin in patients with hypertensive disease].
Topics: Adolescent; Adult; Aged; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1976 |
The renin-angiotensin systems in adrenal-regeneration hypertension.
Topics: Adrenal Cortex; Adrenal Glands; Adrenalectomy; Angiotensin II; Animals; Blood Pressure; Brain; Female; Hypertension; Organ Size; Prostaglandins E; Rats; Regeneration; Renin | 1976 |
The effect of furosemide stimulation on renin secretion and its application in examining activity of the renin-angiotensin system.
Topics: Adult; Angiotensin II; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Natriuresis; Posture; Renin; Stimulation, Chemical | 1976 |
[Blood pressure behavior following 1-sar-8-ala-angiotensin II (saralasin) in essential and renovascular hypertension].
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Saralasin | 1976 |
[Diagnostic relevancy of saralasin in renin-dependent hypertension].
Topics: Angiotensin II; Humans; Hypertension; Renin; Saralasin | 1976 |
[Clinical and experimental studies on the angiotensin inhibitor 1-sar-8-ile-angiotensin II (P 165)].
Topics: Adult; Angiotensin II; Blood Pressure; Glomerular Filtration Rate; Humans; Hypertension; Middle Aged; Renin; Saralasin | 1976 |
[Acute and chronic beta-receptor blockade: influence on blood pressure and on the renin-angiotensin-aldosterone system in essential hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Pindolol; Propranolol; Pulse; Renin; Time Factors | 1976 |
Ultrastructural investigation of peripheral arterial vessels in the cortex of rats with experimental hypertension.
Topics: Angiotensin II; Animals; Capillary Permeability; Cerebral Arteries; Cerebral Cortex; Humans; Hypertension; Hypertension, Renal; Male; Neurotic Disorders; Rats | 1976 |
The renal humoral system: a cause of hypertension?
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney; Renin | 1975 |
Hypertension and renal diseases.
Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Humans; Hypertension; Hypertension, Malignant; Kidney Diseases; Renin | 1975 |
Prostaglandins and the regulation of blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Humans; Hypertension; Kidney; Norepinephrine; Pressoreceptors; Prostaglandins; Prostaglandins A; Prostaglandins E; Rats; Regional Blood Flow; Vasomotor System; Water-Electrolyte Balance | 1975 |
Overall circulatory control in hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Diuresis; Feedback; Hemodynamics; Homeostasis; Humans; Hypertension; Kidney Diseases; Renin; Sympathetic Nervous System; Vascular Resistance | 1976 |
The effects of saralasin, an angiotensin II antagonist, on blood pressure and the renin-angiotensin-aldosterone system in normal and hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Depression, Chemical; Diet; Female; Humans; Hypertension; Male; Middle Aged; Renin; Saralasin; Sodium | 1976 |
Angiotensin II blockade in patients with essential hypertension.
Topics: Angiotensin II; Blood Pressure; Diet; Humans; Hypertension; Renin; Saralasin; Sodium | 1976 |
Angiotensin II blockade in patients with essential hypertension.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Saralasin | 1976 |
The role of sodium retention in Goldblatt 2-kidney hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Nephrectomy; Rats; Saralasin; Sodium | 1976 |
Angiotensin II blockade in normal subjects and essential hypertensive patients.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Renin; Saralasin; Sodium | 1976 |
Determination of renin-dependency and sodium-dependency in the three renin sub-groups of essential hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Renin; Saralasin; Sodium | 1976 |
Deoxycorticosterone hypertension in the pig.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Hypertension; Norepinephrine; Swine; Time Factors; Vascular Resistance | 1976 |
The arteriolar lesions of steroid hypertension in rats.
Topics: Angiotensin II; Animals; Arteries; Desoxycorticosterone; Hypertension; Microscopy, Electron; Rats | 1976 |
Synthesis of endocrine control in hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Feedback; Hypertension; Kidney; Potassium; Sodium; Vasopressins | 1976 |
Lack of hypotensive effect on central injection of angiotensin inhibitors in spontaneously hypertensive (SH) and normotensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Hypertension; Male; Rats; Saralasin | 1976 |
Blood pressure response to central and peripheral injection of angiotensin II and 8-C-phenylglycine analogue of angiotensin II in rats with experimental hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Dose-Response Relationship, Drug; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Rats | 1976 |
Increased vascular permeability for plasma components during acute angiotensin hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Aorta; Arteries; Blood Proteins; Coronary Vessels; Hypertension; Kidney; Permeability; Rats; Vascular Resistance | 1976 |
Ultrastructural arteriolar lesions and permeability changes in acute angiotensin-induced hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Arteries; Cell Membrane Permeability; Hypertension; Intestine, Small; Rats; Vascular Diseases; Vascular Resistance | 1976 |
The sausage-string pattern in the pial vessels in acute, angiotensin-induced hypertension--vasospasm or vasodilatation?
Topics: Angiotensin II; Animals; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Homeostasis; Hypertension; Pia Mater; Rats; Vascular Diseases; Vasomotor System | 1976 |
The intrinsic brain iso-renin--angiotensin system in the rat: its possible role in central mechanisms of blood pressure regulation.
Topics: Angiotensin II; Angiotensins; Animals; Blood Pressure; Brain; Diabetes Insipidus; Hypertension; Injections, Intraventricular; Rats; Saralasin | 1975 |
Role of juxtagolmerular apparatus in renal allograft rejection.
Topics: Aldosterone; Angiotensin II; Animals; Dogs; Erythropoietin; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Hypoxia; Juxtaglomerular Apparatus; Kidney Transplantation; Renin; Sodium; Transplantation, Homologous; Water-Electrolyte Balance | 1975 |
Renin and hypertension.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Diuretics; Hyperaldosteronism; Hypertension; Juxtaglomerular Apparatus; Metabolism; Radioimmunoassay; Renin; Sodium; Sympathetic Nervous System | 1975 |
Pathogenesis of hypertension in Cushing's syndrome.
Topics: 17-Ketosteroids; Adult; Angiotensin II; Cushing Syndrome; Diet; Female; Humans; Hydrocortisone; Hydroxysteroids; Hypertension; Male; Middle Aged; Potassium; Renin; Sodium Chloride | 1975 |
Hypertension corrected by discontinuing chronic sodium bicarbonate ingestion. Subsequent transient hypoaldosteronism.
Topics: 17-Hydroxycorticosteroids; Aldosterone; Angiotensin II; Antihypertensive Agents; Bicarbonates; Calcium; Diet; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middle Aged; Potassium; Renin; Sodium | 1975 |
Workup of the newly discovered hypertensive patient.
Topics: Adult; Aldosterone; Angiotensin II; Cardiac Output; Cerebrovascular Disorders; Contraceptives, Oral; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Mass Screening; Medical History Taking; Middle Aged; Pheochromocytoma; Renin; United States; Uremia; Urography; Vascular Diseases | 1975 |
Pathophysiology of angiotensin-salt hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Urea Nitrogen; Body Weight; Calcium; Corticosterone; Desoxycorticosterone; Extracellular Space; Hematocrit; Hypertension; Magnesium; Male; Nephrectomy; Plasma Volume; Rats; Rats, Inbred Strains; Renin; Secretory Rate; Sodium Chloride; Thirst | 1975 |
[Hypertension 1974].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Catecholamines; Humans; Hypertension; Prostaglandins; Renin; Serotonin; Sympathetic Nervous System | 1975 |
Circulating renin in essential hypertension: an evaluation of its significance in the Japanese population.
Topics: Adolescent; Adult; Age Factors; Aged; Angiotensin II; Asian People; Child; Female; Humans; Hypertension; Japan; Kidney; Kidney Diseases; Male; Middle Aged; Prognosis; Radioimmunoassay; Renin; Retinal Diseases; Sex Factors; Veins | 1975 |
Identification of angiotensinogenic hypertension in man using 1-sar-8-ala-angiotensin II (Saralasin, P-113).
Topics: Adult; Aged; Angiography; Angiotensin II; Blood Pressure; Humans; Hypertension; Ischemia; Kidney; Middle Aged; Nephrectomy; Radioisotope Renography; Regional Blood Flow; Renal Veins; Renin; Saralasin; Urography | 1975 |
Evidence for the existence of an acetone soluble renin inhibiting factor in normal human plasma.
Topics: Acetone; Angiotensin II; Angiotensinogen; Humans; Hypertension; In Vitro Techniques; Kinetics; Radioimmunoassay; Renin; Solubility; Time Factors; Uremia | 1975 |
[Renin, angiotensin and aldosterone in the diagnosis of hypertension].
Topics: Aldosterone; Angiotensin II; Blood Volume; Diagnosis, Differential; Humans; Hypertension; Hypertension, Malignant; Hypertension, Portal; Juxtaglomerular Apparatus; Renin; Sodium; Vascular Resistance | 1975 |
[Essential hypertension and the renin-angiotensin-aldosterone system].
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Humans; Hypertension; Middle Aged; Renin | 1975 |
Cardiovascular changes in pregnancy.
Topics: Angiotensin II; Arm; Arteries; Autonomic Nervous System; Blood Pressure; Blood Viscosity; Blood Volume; Brain; Cardiac Output; Cardiovascular Physiological Phenomena; Cerebrovascular Circulation; Epinephrine; Female; Humans; Hypertension; Kidney; Leg; Liver Circulation; Norepinephrine; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Uterus; Vascular Resistance; Vasopressins | 1975 |
Enhancement of hypothalamic pressor responses in spontaneously hypertensive rats.
Topics: Anesthesia, General; Angiotensin II; Animals; Blood Pressure; Electric Stimulation; Electrodes, Implanted; Female; Heart Rate; Hypertension; Hypothalamus; Norepinephrine; Rats; Urethane | 1975 |
Control of aldosterone secretion in the spontaneously hypertensive rat.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Hypertension; Kidney; Male; Pituitary Gland; Rats; Renin | 1975 |
Studies on etiology of essential hypertension. Hemodynamics, water-sodium balance and response to pressor substances during long-term sodium restriction and after spontaneous blood pressure fall--.
Topics: Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Heart; Hemodynamics; Hexamethonium Compounds; Humans; Hypertension; Injections, Intramuscular; Norepinephrine; Plasma Volume; Potassium; Radioimmunoassay; Renin; Sodium; Vascular Resistance | 1975 |
Effect of pressor agents on blood pressure, plasma renin activity and plasma aldosterone concentration in essential hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Infusions, Parenteral; Male; Middle Aged; Norepinephrine; Renin | 1975 |
[Plasma aldosterone and plasma renin activity in patients with essential and renal hypertension under acute stimulation with saline depletion and acute suppression with saline infusion].
Topics: Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Furosemide; Glomerulonephritis; Hematocrit; Humans; Hypertension; Hypertension, Renal; Male; Potassium; Pyelonephritis; Renin; Sodium | 1975 |
Vasodepressor activity of renal medulla of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Biological Assay; Blood Pressure; Chickens; Female; Hypertension; Kidney; Kidney Medulla; Male; Prostaglandins; Rats; Renin | 1975 |
Therapy and prognosis of hypertension in chronic nephritis.
Topics: Adult; Aldosterone; Angiotensin II; Blood Volume; Catecholamines; Chronic Disease; Creatinine; Extracellular Space; Female; Glomerulonephritis; Humans; Hydralazine; Hypertension; Hypertension, Renal; Male; Methyldopa; Middle Aged; Prognosis; Propranolol | 1975 |
Radioimmunoassay and pharmacokinetics of saralasin in the rat and hypertensive patients.
Topics: Adult; Alanine; Angiotensin II; Animals; Antibody Specificity; Antigen-Antibody Complex; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Hypertension; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Iodine Radioisotopes; Kinetics; Male; Middle Aged; Protein Binding; Rabbits; Radioimmunoassay; Rats; Renin; Sarcosine | 1975 |
[Renin-angiotensin - aldosterone system in essential hypertension].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Radioimmunoassay; Renin | 1975 |
[Studies on the renin-angiotensin system in adrenal regeneration hypertension (author's transl)].
Topics: Adrenal Glands; Adrenal Medulla; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Female; Furosemide; Hypertension; Kidney; Male; Organ Size; Potassium; Rats; Regeneration; Renin; Sodium; Sodium Chloride | 1975 |
Extensive hypertensive work-up. In rebuttal to Dr. Finnerty.
Topics: Angiotensin II; Antihypertensive Agents; Attitude to Health; Costs and Cost Analysis; Humans; Hypertension; Renin; United States | 1975 |
Clinical implications of renin in the hypertensive patient.
Topics: Angiotensin II; Blood Pressure; Blood Volume; Humans; Hyperaldosteronism; Hypertension; Renin; Saralasin; Sodium; Teprotide | 1975 |
[Renin-angiotensin system and hypertension].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1975 |
Effects of 1-sarcosine-8-isoleucine-angiotensin II on blood pressure and plasma renin activity in various types of hypertension.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Child; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Middle Aged; Renin | 1975 |
Jeremiah Metzger lecture, 1974: The renin-angiotensin system. Some new aspects.
Topics: Adult; Age Factors; Angiotensin II; Animals; Brain Chemistry; Cerebrovascular Disorders; Dogs; Humans; Hypertension; Isoenzymes; Middle Aged; Myocardial Infarction; Racial Groups; Rats; Renin; Sodium; Submandibular Gland | 1975 |
Changes in the renin-angiotensin system in primigravidae with hypertensive disease of pregnancy.
Topics: Adolescent; Adult; Angiotensin II; Animals; Blood Pressure; Dogs; Edema; Female; Gestational Age; Humans; Hypertension; Labor, Induced; Maternal Age; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Rabbits; Renin | 1975 |
Interrelationships of the renin angiotensin system and the sympathetic nervous system in the pathogenesis of hypertension in man-a hypothesis.
Topics: Angiotensin II; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output; Diet, Sodium-Restricted; Humans; Hypertension; Natriuresis; Norepinephrine; Renin; Sympathetic Nervous System | 1975 |
Plasma renin and angiotensin levels in experimental hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, Sodium-Restricted; Hypertension; Kidney; Rats; Renal Artery; Renin; Sodium; Time Factors | 1975 |
[Clinical importance of the renin-angiotensin-aldosterone system in hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin | 1975 |
Relation of renin status to neurogenic vascular resistance in borderline hypertension.
Topics: Adolescent; Adult; Angiotensin II; Atropine; Autonomic Nerve Block; Blood Pressure; Cardiac Output; Humans; Hypertension; Male; Phentolamine; Propranolol; Renin; Vascular Resistance | 1975 |
Abnormalities of renal perfusion and the renal pressor system in dogs with chronic aortic coarctation.
Topics: Angiotensin II; Animals; Aortic Coarctation; Blood Pressure; Dogs; Hypertension; Kidney; Renin | 1975 |
Fluid balance, renal function, and blood pressure.
Topics: Angiotensin II; Blood Pressure; Body Fluids; Cardiac Output; Glomerular Filtration Rate; Homeostasis; Humans; Hypertension; Hypertension, Renal; Kidney; Kidney Diseases; Renin; Vascular Resistance; Vasomotor System; Water-Electrolyte Balance | 1975 |
Indirect blood pressure measurements in the rabbit: correlations with direct aortic and ear pressures.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Blood Pressure Determination; Cadmium; Chronic Disease; Ear, External; Female; Hypertension; Hypertension, Renal; Male; Rabbits | 1975 |
Synthesis of lysophosphatidylethanolamine analogs that inhibit renin activity.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Depression, Chemical; Dogs; Hypertension; In Vitro Techniques; Lysophospholipids; Phosphatidylethanolamines; Rats; Renin; Structure-Activity Relationship | 1975 |
Contribution to the study of the renin--angiotensin system by means of radioimmunoassay.
Topics: Adult; Aged; Angiotensin II; Animals; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Physical Exertion; Radioimmunoassay; Rats; Renin | 1975 |
[Evidence for circadian variability in the renin-angiotensin II system (author's transl)].
Topics: Angiotensin II; Circadian Rhythm; Hypertension; Hypertension, Renal; Renin | 1975 |
Hypertension in primary hyperparathyroidism: the role of the renin-angiotensin system.
Topics: Adult; Aged; Angiotensin II; Child; Child, Preschool; Female; Humans; Hypercalcemia; Hyperparathyroidism; Hypertension; Kidney; Male; Middle Aged; Renin | 1975 |
Oral contraceptive pill hypertension.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Body Weight; Contraceptives, Oral; Diuresis; Estrogens; Female; Hemodynamics; Humans; Hypertension; Natriuresis; Pituitary-Adrenal System; Renin; Sodium; Sympathetic Nervous System | 1975 |
Effect of angiotensin II upon platelet adhesiveness and the thrombelastogram in patients with essential arterial hypertension.
Topics: Adult; Aged; Angiotensin II; Blood Platelets; Humans; Hypertension; Middle Aged; Platelet Adhesiveness; Thrombelastography; Urinary Tract Infections | 1975 |
[Hypertension and renin/angiotensin. Physiopathological and therapeutical aspects].
Topics: Angiotensin II; Antihypertensive Agents; Humans; Hypertension; Renin | 1975 |
[Effect of angiotensin II on the pattern of plasma free fatty acids in 2 hypertension models in rabbits].
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fatty Acids, Nonesterified; Hypertension; Hypertension, Renal; Male; Rabbits; Time Factors | 1975 |
[Renin-angiotensin-aldosterone system in hypertensive disease and arteriosclerotic myocardioslcerosis complicated by chronic circulatory insufficiency].
Topics: Aged; Aldosterone; Angiotensin II; Blood Circulation; Chronic Disease; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1975 |
[Behavior of blood pressure during oral hormonal anticonception].
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Time Factors | 1975 |
Plasma renin activity in hypertension.
Topics: Adult; Angiotensin II; Extracellular Space; Feedback; Humans; Hypertension; Hypertension, Renal; Kidney Neoplasms; Mineralocorticoids; Radioimmunoassay; Renal Artery Obstruction; Renin; Risk; Secretory Rate; Sodium | 1975 |
The influence of prostaglandins A2 and E2 on the kinetics of the renin reaction in the presence of normal and hypertensive plasma.
Topics: Angiotensin II; Humans; Hypertension; Kinetics; Prostaglandins A; Prostaglandins E; Radioimmunoassay; Renin | 1975 |
Adrenocortical hormones as agents in the production of hypertensive cerebrovascular disease.
Topics: Adrenalectomy; Angiotensin II; Animals; Blood-Brain Barrier; Cerebrovascular Disorders; Corticosterone; Epinephrine; Female; Hypertension; Norepinephrine; Rats | 1975 |
[Experimental hypertension induced with pronase].
Topics: Angiotensin II; Animals; Blood Pressure; Blood Protein Electrophoresis; Hypertension; Male; Pronase; Rats | 1975 |
[Arterial regulation in labile hypertension: the behavior of some humoral indices during orthostatism].
Topics: Angiotensin II; Blood Volume; Catecholamines; Humans; Hypertension; Osmotic Pressure; Posture; Renin; Vanilmandelic Acid; Vasomotor System | 1975 |
[Significance of radioimmunological determination as a tool for clinical research].
Topics: Angiotensin II; Diabetes Mellitus; Growth Hormone; Humans; Hypertension; Insulin; Radioimmunoassay; Research | 1975 |
[Renin and aldosterone].
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Juxtaglomerular Apparatus; Liver Cirrhosis; Radioimmunoassay; Renin | 1975 |
[Ultrastructural observations in the lamina elastica interna and adjacent tissue regions of the arterioles of rats impaired by hypertension of different pathogenesis (author's transl)].
Topics: Angiotensin II; Animals; Descemet Membrane; Disease Models, Animal; Elastic Tissue; Endothelium; Hypertension; Male; Rats | 1975 |
Hypertension and insurance.
Topics: Adult; Angiotensin II; Contraceptives, Oral; Female; Humans; Hypertension; Insurance, Life; Renin | 1975 |
The role of humoral factors in the etiopathogenesis and course of hypertension in man.
Topics: Angiotensin II; Catecholamines; Humans; Hypertension; Renin; Steroids | 1975 |
The role of membrane parameters and of filtration pressure in the determination of the shape of the polyvinylpyrrolidone sieving curve. An in vitro and in vivo study.
Topics: Angiotensin II; Animals; Dogs; Filtration; Glomerular Filtration Rate; Hypertension; Kidney Glomerulus; Membranes; Models, Biological; Permeability; Povidone; Pressure | 1975 |
[Effects of angiotensin II analogue (1-sarcosine, 8-isoleucine-angiotensin II) in various types of hypertension].
Topics: Adolescent; Adult; Angiotensin II; Child; Female; Humans; Hypertension; Male; Middle Aged | 1975 |
[Hypertension in the aged. (4) Renal and hormonal factors].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Desoxycorticosterone; Hormones; Humans; Hypertension; Middle Aged; Prostaglandins; Renin | 1975 |
[A reduced aldosterone response to infused angiotensin II in low renin essential hypertension (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1975 |
[Effect of angiotensin II on the conditional relfex response patterns of neurotic albino rats].
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Male; Neurotic Disorders; Rats; Reflex; Stress, Psychological | 1975 |
[Studies on placental blood flow under drug induced hypertension (animal experiments) (author's transl)].
Topics: Angiotensin II; Animals; Blood Pressure; Epinephrine; Female; Hypertension; Ischemia; Placenta; Pregnancy; Rabbits; Regional Blood Flow; Time Factors | 1975 |
Sympathetic control of cerebral blood flow in acute arterial hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Aorta; Aorta, Thoracic; Blood Flow Velocity; Blood Pressure; Blood-Brain Barrier; Cats; Cerebrovascular Circulation; Electric Stimulation; Female; Hypertension; Male; Metaraminol; Sympathetic Nervous System; Vagus Nerve; Vasomotor System | 1976 |
Plasma renin activity as a function of age in two new strains of spontaneously hypertensive and normotensive rats.
Topics: Aging; Anesthesia, General; Angiotensin II; Animals; Body Weight; Ethyl Ethers; Hypertension; Male; Rats; Renin | 1976 |
[Principle and range of application of radioimmunoassay. (V). The renin-angiontensin-aldosterone system].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Juxtaglomerular Apparatus; Radioimmunoassay; Renin | 1976 |
Renin-angiotensin-aldosterone system in experimental renal hypertension in the rabbit.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Corticosterone; Depression, Chemical; Desoxycorticosterone; Eating; Hematocrit; Hypertension; Male; Potassium; Rabbits; Regional Blood Flow; Renin; Saralasin; Sodium | 1976 |
Studies of plasma renin activity in coarctation of the aorta.
Topics: Adolescent; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Child; Diazoxide; Disease Models, Animal; Dogs; Hematocrit; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Male; Physical Exertion; Potassium; Renin; Sodium | 1976 |
Measurement of angiotensin II in human plasma: technical modifications and practical experience.
Topics: Adult; Angiotensin II; Chromatography, Ion Exchange; Humans; Hypertension; Kidney Diseases; Middle Aged; Radioimmunoassay; Renin; Time Factors | 1976 |
Relation between plasma renin activity, angiotensin, and aldosterone and blood pressure in mild untreated hypertension.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Arteries; Blood Pressure; Diet; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis; Renin; Sodium Chloride; Veins | 1976 |
Saralasin infusion--a new diagnositc technique.
Topics: Angiotensin II; Humans; Hypertension; Perfusion; Saralasin | 1976 |
[Hypotensive effects of safflower yellow in spontaneously hypertensive rats and influence on plasma renin activity and angiotensin II level].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Chalcone; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Renin | 1992 |
Altered signal transduction in vascular smooth muscle cells of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Calcium Channels; Hypertension; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction | 1992 |
The effect of angiotensin II on platelet intracellular free calcium concentration in human pregnancy.
Topics: Adult; Angiotensin II; Blood Platelets; Blood Pressure; Calcium; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Prospective Studies; Second Messenger Systems | 1992 |
In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalaprilat; Endopeptidases; Hypertension; Male; Neprilysin; Osmolar Concentration; Peptide Fragments; Prolyl Oligopeptidases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serine Endopeptidases; Time Factors | 1992 |
Blunted effects of endothelin upon small subcutaneous resistance arteries of mild essential hypertensive patients.
Topics: Adipose Tissue; Adult; Angiotensin II; Arginine Vasopressin; Arteries; Biopsy; Dose-Response Relationship, Drug; Endothelins; Humans; Hypertension; In Vitro Techniques; Male; Norepinephrine; Vascular Resistance | 1992 |
The ouabain-dependent Na(+)-K+ pump and the brain renin-angiotensin system.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Dogs; Female; Hypertension; Male; Ouabain; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase | 1992 |
Effect of angiotensin converting enzyme inhibitors upon brain angiotensin II binding.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Cells, Cultured; Down-Regulation; Hypertension; Iodine Radioisotopes; Neurons; Protein Binding; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Angiotensin | 1992 |
[Animal models of various hypertensions].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Androgens; Angiotensin II; Animals; Catecholamines; Choline Deficiency; Disease Models, Animal; Glycyrrhiza; Growth Hormone; Hypertension; Metyrapone; Plants, Medicinal; Rats; Renin; Sodium, Dietary; Streptozocin | 1992 |
Hypertension in Dahl salt-sensitive rats: biochemical and immunohistochemical studies.
Topics: Angiotensin II; Animals; Hypertension; Immunohistochemistry; Kallikrein-Kinin System; Kallikreins; Kidney; Male; Organ Size; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sodium, Dietary; Time Factors | 1992 |
Influence of dietary protein on glomerular angiotensin II-receptor binding in normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Dietary Proteins; Female; Hypertension; Kidney Cortex; Kidney Glomerulus; Protein Binding; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renin; Water-Electrolyte Balance | 1992 |
Comparative study of platelet angiotensin II binding and the angiotensin II sensitivity test as predictors of pregnancy-induced hypertension.
Topics: Adult; Angiotensin II; Blood Platelets; Blood Pressure; Female; Humans; Hypertension; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Protein Binding | 1992 |
Na(+)-K+ pump and Na(+)-K+ co-transport in cultured vascular smooth muscle cells from spontaneously hypertensive and normotensive rats: baseline activity and regulation.
Topics: Angiotensin II; Animals; Carrier Proteins; Hypertension; In Vitro Techniques; Male; Membrane Proteins; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rubidium Radioisotopes; Second Messenger Systems; Sodium Radioisotopes; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase | 1992 |
Altered number of platelet angiotensin II receptors in relation to plasma agonist concentrations in normal and hypertensive pregnancy.
Topics: Adult; Angiotensin II; Blood Platelets; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Radioligand Assay; Receptors, Angiotensin; Risk Factors | 1992 |
Need for both angiotensin converting enzyme and angiotensinase specific inhibition for a reliable assessment of angiotensin II levels in human plasma.
Topics: Adult; Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Peptidyl-Dipeptidase A; Protease Inhibitors; Radioimmunoassay | 1992 |
Angiotensin II receptor antagonist delays renal damage and stroke in salt-loaded Dahl salt-sensitive rats.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Cerebrovascular Disorders; Hypertension; Imidazoles; Kidney Diseases; Losartan; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium, Dietary; Survival Analysis; Tetrazoles | 1992 |
Impaired ability of prostaglandins to buffer renal vasoconstriction in genetically hypertensive rats.
Topics: Angiotensin II; Animals; Bradykinin; Buffers; Hypertension; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Reference Values; Renal Circulation; Vasoconstriction; Vasodilator Agents | 1992 |
Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Glucose; Blood Pressure; Cholesterol; Dietary Fats, Unsaturated; Electrolytes; gamma-Linolenic Acid; Hypertension; Linolenic Acids; Male; Norepinephrine; Plant Oils; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sesame Oil; Triglycerides | 1992 |
Vascular tissue renin-angiotensin system in hypertensive humans.
Topics: Adenosine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Coronary Vessels; Forearm; Humans; Hypertension; Isoproterenol; Norepinephrine; Receptors, Adrenergic, beta; Renin; Renin-Angiotensin System; Saralasin | 1992 |
Glomerular hyperfiltration in essential hypertension: hormonal aspects.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Dietary Proteins; Enalapril; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Renal Circulation; Renin | 1992 |
Angiotensin converting activity assessed in vivo is increased in hereditary hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Hypertension; Lung; Male; Nitroprusside; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Regression of hypertension-induced vascular hypertrophy by an ACE inhibitor and calcium antagonist in the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Hydralazine; Hypertension; Hypertrophy; Indans; Male; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 1992 |
Renal vascular responses in spontaneously hypertensive rats chronically treated with manidipine.
Topics: Air Pressure; Angiotensin II; Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Dihydropyridines; Endothelins; Heart Rate; Hypertension; Infusions, Intravenous; Injections, Intraventricular; Kidney; Male; Natriuresis; Nitrobenzenes; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Sodium; Stress, Physiological; Stress, Psychological; Time Factors | 1992 |
Expression of tenascin by vascular smooth muscle cells. Alterations in hypertensive rats and stimulation by angiotensin II.
Topics: Angiotensin II; Animals; Arteries; Cell Adhesion; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Extracellular Matrix Proteins; Hypertension; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Tenascin | 1992 |
Combination of nifedipine and doxazosin in essential hypertension.
Topics: Aged; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Doxazosin; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Phenylephrine; Prazosin | 1992 |
Alpha-adrenergic and angiotensin II pressor sensitivity in hypertensive patients treated with an angiotensin-converting enzyme inhibitor.
Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Phenylephrine; Pressoreceptors; Pyridazines; Random Allocation; Renin | 1992 |
Antihypertensive mechanism of amlodipine in essential hypertension: role of pressor reactivity to norepinephrine and angiotensin II.
Topics: Adult; Amlodipine; Angiotensin II; Antihypertensive Agents; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Electrolytes; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Renin-Angiotensin System | 1992 |
Effects of losartan, a nonpeptide angiotensin II receptor antagonist, on cardiac hypertrophy and the tissue angiotensin II content in spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Cardiomegaly; Heart Rate; Heart Ventricles; Hypertension; Imidazoles; Losartan; Male; Organ Size; Radioimmunoassay; Rats; Rats, Inbred SHR; Renin; Tetrazoles | 1992 |
Long-term angiotensin II antagonism in spontaneously hypertensive rats: effects on blood pressure and cardiovascular amplifiers.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Cardiovascular Agents; Cardiovascular Physiological Phenomena; Cardiovascular System; Hindlimb; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Time Factors | 1992 |
Enhanced renal response to intracerebroventricular angiotensins II and III in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Injections, Intraventricular; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Direct, simplified, and sensitive assay of angiotensin II in plasma extracts performed with a high-affinity monoclonal antibody.
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Chromatography, High Pressure Liquid; Humans; Hypertension; Mice; Mice, Inbred BALB C; Peptide Fragments; Radioimmunoassay; Reference Values | 1992 |
Enhanced contraction to noradrenaline, serotonin and nerve stimulation but normal endothelium-derived relaxing factor response in skin small arteries in human primary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adult; Angiotensin II; Arteries; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Hypertension; Male; Middle Aged; Muscle, Smooth, Vascular; Myography; Nitric Oxide; Norepinephrine; Prostaglandin Endoperoxides, Synthetic; Serotonin; Skin; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1992 |
Antihypertensive and hormonal activity of MK 954 in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Hormones; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System; Tetrazoles | 1992 |
Impaired renal vascular reactivity in prehypertensive Dahl salt-sensitive rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiac Output; Endothelins; Hypertension; Male; Nitroprusside; Norepinephrine; Rats; Rats, Inbred Strains; Renal Circulation; Vascular Resistance | 1992 |
Magnesium pyrrolidone carboxylate infusion reduces angiotensin II pressor response in pregnant women at risk for hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Magnesium; Pregnancy; Pregnancy Complications, Cardiovascular; Pyrrolidinones; Risk Factors | 1992 |
Differential regulation of rat AT1a and AT1b receptor mRNA.
Topics: Adrenal Glands; Angiotensin II; Animals; Base Sequence; Gene Expression; Hypertension; Kinetics; Liver; Male; Molecular Sequence Data; Nephrectomy; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Sequence Deletion | 1992 |
A vasopressor factor partially purified from human parathyroid glands.
Topics: Angiotensin II; Animals; Endopeptidases; Humans; Hyperparathyroidism; Hypertension; In Vitro Techniques; Kidney; Kidney Failure, Chronic; Male; Mass Spectrometry; Muscle, Smooth, Vascular; Parathyroid Glands; Rats; Rats, Inbred WKY; Renal Artery; Renal Circulation; Tissue Extracts; Vasoconstrictor Agents | 1992 |
Effects of aging and hypertension on plasma angiotensin II and platelet angiotensin II receptor density.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Platelets; Humans; Hypertension; Middle Aged; Receptors, Angiotensin; Reference Values; Regression Analysis | 1992 |
Immunohistochemical findings of juxtaglomerular cells on acute phase in two-kidney Goldblatt hypertensive rats and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Captopril; Hypertension; Hypertension, Renovascular; Immunohistochemistry; Juxtaglomerular Apparatus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Renin; Renin-Angiotensin System; Time Factors | 1992 |
Hypertension during chronic exposure to cold: comparison between Sprague-Dawley and Long-Evans strains.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cold Temperature; Dopamine; Drinking Behavior; Eating; Epinephrine; Hypertension; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Species Specificity | 1992 |
Response of plasma renin-angiotensin system to a single captopril administration in patients receiving long-term treatment with captopril.
Topics: Aldosterone; Angiotensin II; Angiotensin III; Blood Pressure; Captopril; Drug Tolerance; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1992 |
Increased platelet angiotensin II receptor number in pregnancy-induced hypertension.
Topics: Adult; Angiotensin II; Blood Platelets; Female; Humans; Hypertension; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Receptors, Angiotensin; Reference Values; Renin | 1992 |
Effect of intracarotid infusion of etoposide with angiotensin II-induced hypertension on the blood-brain barrier and the brain tissue.
Topics: Angiotensin II; Animals; Atrophy; Blood-Brain Barrier; Brain; Brain Edema; Carotid Arteries; Demyelinating Diseases; Etoposide; Evans Blue; Hypertension; Infusions, Intra-Arterial; Male; Necrosis; Rats; Rats, Inbred F344 | 1992 |
Enhanced expression of inhibitory guanine nucleotide regulatory protein in spontaneously hypertensive rats. Relationship to adenylate cyclase inhibition.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Cholera Toxin; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Immunoblotting; Myocardium; Oxotremorine; Pertussis Toxin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Virulence Factors, Bordetella | 1992 |
Receptor-mediated effects of angiotensin II on growth of vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Cell Count; Cell Division; DNA; Hypertension; Ligands; Male; Muscle Proteins; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 1992 |
Non-modulation as an intermediate phenotype in essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Phenotype; Regional Blood Flow; Renal Circulation; Reproducibility of Results | 1992 |
Sympathetic overactivity in patients with chronic renal failure.
Topics: Angiotensin II; Female; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Leg; Male; Middle Aged; Nephrectomy; Norepinephrine; Peroneal Nerve; Renal Dialysis; Renin; Sympathetic Nervous System; Vascular Resistance | 1992 |
Differential effects of intravenous hydralazine on myoendometrial and placental blood flow in hypertensive pregnant ewes.
Topics: Adrenal Glands; Angiotensin II; Animals; Endometrium; Female; Hydralazine; Hypertension; Injections, Intravenous; Microspheres; Myometrium; Placenta; Pregnancy; Regional Blood Flow; Renal Circulation; Sheep; Vascular Resistance | 1992 |
[Changes in the humoral systems in juvenile arterial hypertension and their correction by using nifedipine and anaprilin].
Topics: Adolescent; Aldosterone; Angiotensin II; Blood Pressure; Drug Evaluation; Humans; Hypertension; Nifedipine; Propranolol; Renin; Renin-Angiotensin System; Testosterone | 1992 |
Thirst and hypertension remaining after intracarotid infusions of angiotensin II in the sheep.
Topics: Angiotensin II; Animals; Blood Pressure; Carotid Arteries; Cerebral Ventricles; Female; Hypertension; Infusions, Intravenous; Sheep; Thirst | 1992 |
Angiotensin-II induction of plasminogen activator inhibitor-1 gene expression in astroglial cells of normotensive and spontaneously hypertensive rat brain.
Topics: Angiotensin II; Animals; Astrocytes; Brain; Cells, Cultured; Gene Expression Regulation; Hypertension; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System | 1992 |
Acupuncture at otoacupoint heart for treatment of vascular hypertension.
Topics: Acupuncture Points; Acupuncture Therapy; Adult; Aged; Angiotensin II; Ear, External; Electroacupuncture; Female; Humans; Hypertension; Male; Middle Aged | 1992 |
Serial measurements of platelet angiotensin II binding in two patients with hypertension in pregnancy: case reports.
Topics: Adult; Angiotensin II; Blood Platelets; Creatinine; Female; Humans; Hypertension; Platelet Count; Pregnancy; Pregnancy Complications, Cardiovascular; Uric Acid | 1992 |
[Salt-responder and non-responder: general concept].
Topics: Angiotensin II; Animals; Blood Proteins; Cardenolides; Cardiac Output; Digoxin; Extracellular Space; Female; Humans; Hypertension; Kidney; Male; Saponins; Sodium; Sodium, Dietary; Sympathetic Nervous System; Vascular Resistance | 1992 |
[Non-modulating essential hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diet, Sodium-Restricted; Humans; Hypertension; Kidney; Renal Circulation; Renin-Angiotensin System; Sodium | 1992 |
Adrenal and circulating renin-angiotensin system in stroke-prone hypertensive rats.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Cerebrovascular Disorders; Concanavalin A; Enzyme Precursors; Hypertension; Immune Sera; Male; Nephrectomy; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 1992 |
Sensitivity to angiotensin and the risk for hypertension.
Topics: Angiotensin II; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Hemodynamics; Humans; Hypertension; Male; Risk Factors | 1992 |
Angiotensin AT2 receptors regulate cerebral blood flow in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Male; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Sodium Chloride | 1992 |
The rate of increase in hematocrit, humoral vasoactive substances and blood pressure changes in hemodialysis patients treated with recombinant human erythropoietin or blood transfusion.
Topics: Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Blood Transfusion; Catecholamines; Dopamine; Epinephrine; Erythropoietin; Female; Hematocrit; Humans; Hypertension; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Norepinephrine; Pilot Projects; Recombinant Proteins; Renal Dialysis; Renin | 1992 |
Endocrine sodium and volume regulation in familial hyperkalemia with hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Family; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Male; Pedigree; Syndrome | 1992 |
Cardiovascular simulation using a multiple modeling method on a digital computer--simulation of interaction between the cardiovascular system and angiotensin II.
Topics: Angiotensin II; Blood Flow Velocity; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Computer Simulation; Computers; Heart Neoplasms; Hemodynamics; Humans; Hypertension; Models, Cardiovascular; Vascular Resistance; Vasoconstriction | 1992 |
New nonpeptide angiotensin II receptor antagonists. 1. Synthesis, biological properties, and structure-activity relationships of 2-alkyl benzimidazole derivatives.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Blood Pressure; Guinea Pigs; Hypertension; Male; Models, Molecular; Molecular Conformation; Molecular Structure; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1992 |
Uterine and umbilical flow velocity waveforms in normotensive and hypertensive subjects during the angiotensin II sensitivity test.
Topics: Adult; Angiotensin II; Blood Flow Velocity; Blood Pressure; Diastole; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Reference Values; Systole; Ultrasonography; Umbilicus; Uterus | 1992 |
Hypertension in insulin-resistant Zucker obese rats is independent of sympathetic neural support.
Topics: Angiotensin II; Animals; Chlorisondamine; Diastole; Heart Rate; Hypertension; Insulin Resistance; Male; Norepinephrine; Obesity; Rats; Rats, Zucker; Sympathetic Nervous System; Systole | 1992 |
Antagonist effect of a receptor-mimicking peptide encoded by human angiotensin II complementary RNA.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies, Monoclonal; Base Sequence; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Hypertension; Male; Molecular Sequence Data; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Angiotensin; RNA, Messenger | 1992 |
Angiotensin II receptors in the solitary-vagal area of hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Vagus Nerve | 1992 |
Increased peripheral resistance during reduced uterine perfusion pressure hypertension in pregnant rabbits.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Female; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Rabbits; Uterus; Vascular Resistance | 1992 |
Phospholipase C responses in cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium; Cells, Cultured; Hypertension; Inositol Phosphates; Iodine Radioisotopes; Male; Protein Binding; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Type C Phospholipases | 1992 |
Depressor effect of blocking angiotensin subtype 1 receptors in anterior hypothalamus.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Hypertension; Hypothalamus, Anterior; Imidazoles; Losartan; Microinjections; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles | 1992 |
Renal injury from angiotensin II-mediated hypertension.
Topics: Angiotensin II; Animals; Cell Division; Hemodynamics; Hypertension; Infusion Pumps, Implantable; Kidney; Kidney Function Tests; Kidney Glomerulus; Kidney Tubules; Male; Platelet-Derived Growth Factor; Rats; Rats, Inbred Strains; Renin; RNA, Messenger | 1992 |
Increased systemic and renal vascular sensitivity to angiotensin II in normotensive men with positive family histories of hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Male; Norepinephrine; Potassium; Radioimmunoassay; Regional Blood Flow; Renin; Sodium; Vascular Resistance | 1992 |
[Antihypertensive effect of a non-peptide angiotensin II receptor antagonist, MK954, in patients with essential hypertension].
Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Tetrazoles | 1992 |
Pressor responsiveness in corticosteroid-induced hypertension in humans.
Topics: Adult; Angiotensin II; Blood Pressure; Blood Vessels; Dexamethasone; Fludrocortisone; Forearm; Hemodynamics; Hormones; Humans; Hypertension; Male; Norepinephrine | 1992 |
Central administration of a specific angiotensin II receptor antagonist on baroreflex function in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Brain; Captopril; Female; Heart Rate; Hypertension; Male; Pressoreceptors; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Reflex; Renin-Angiotensin System | 1991 |
Vascular renin-angiotensin system and neurotransmission in hypertensive persons.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Vessels; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Receptors, Adrenergic, beta; Renin-Angiotensin System; Sympathetic Nervous System; Synaptic Transmission; Vasoconstriction | 1991 |
Role of prostanoids in the increased vascular responsiveness and delayed tachyphylaxis to serotonin in the kidney of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arachidonic Acids; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Hypertension; In Vitro Techniques; Indomethacin; Kidney; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Tachyphylaxis; Thromboxane A2; Vasoconstriction | 1991 |
Kinin receptors of the central nervous system of spontaneously hypertensive rats related to the pressor response to bradykinin.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Catheters, Indwelling; Cerebral Ventricles; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Neurotransmitter | 1991 |
Plasma and tissue kallikrein-kinin systems during acute administration of frusemide in normotensive and hypertensive humans.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dinoprostone; Electrolytes; Female; Furosemide; Humans; Hypertension; Kallikrein-Kinin System; Kallikreins; Male; Middle Aged; Prekallikrein; Renin | 1991 |
Evidence for an intrinsic angiotensin system in the canine pancreas.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Autoradiography; Binding Sites; Dogs; Glucose; Hypertension; Male; Pancreas; RNA, Messenger | 1991 |
Angiotensin-induced hypertension chemotherapy in children with advanced solid tumors.
Topics: Adolescent; Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carcinoma, Hepatocellular; Child; Child, Preschool; Coccyx; Female; Humans; Hypertension; Infant; Infusions, Intravenous; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Staging; Neoplasms; Sacrum; Thoracic Neoplasms | 1991 |
Cardiac and renal hypertrophy is independent of tissue angiotensin converting enzyme and circulating angiotensin II in hypertensive rats.
Topics: Angiotensin II; Animals; Cardiomegaly; Desoxycorticosterone; Hypertension; Hypertension, Renovascular; Hypertrophy; Kidney; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Sodium Chloride | 1991 |
Insulin increases Na(+)-H+ exchange activity in proximal tubules from normotensive and hypertensive rats.
Topics: Adrenergic alpha-Agonists; Amiloride; Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Hypertension; Insulin; Kidney Tubules, Proximal; Parathyroid Hormone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Lateral parabrachial nucleus and angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Pressure; Ganglionic Blockers; Heart Rate; Hexamethonium; Hexamethonium Compounds; Hypertension; Male; Pons; Rats; Rats, Inbred Strains; Receptors, Vasopressin | 1991 |
Low-dose aspirin and vascular response in pregnant patients sensitive to angiotensin II.
Topics: Angiotensin II; Aspirin; Blood Pressure; Drug Interactions; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular | 1991 |
Neural and humoral mechanisms of angiotensin-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Dose-Response Relationship, Drug; Ganglionic Blockers; Heart Rate; Hypertension; Kidney; Nervous System Physiological Phenomena; Norepinephrine; Phenylephrine; Rabbits; Saralasin; Sympathetic Nervous System; Trimethaphan | 1991 |
Hyperreninemia due to increased renal renin synthesis in BioBreeding Worcester rats.
Topics: Angiotensin II; Animals; Diabetes Mellitus; Disease Susceptibility; Hypertension; Immunohistochemistry; Kidney; Rats; Rats, Inbred BB; Rats, Inbred Strains; Renin; RNA, Messenger; Staining and Labeling | 1990 |
Stress-induced proteins in aortic smooth muscle cells and aorta of hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Arsenic; Arsenites; Blotting, Northern; Desoxycorticosterone; Heat-Shock Proteins; Hot Temperature; Hypertension; Methionine; Muscle Proteins; Muscle, Smooth, Vascular; Norepinephrine; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA; Sodium Chloride; Stress, Physiological | 1990 |
Angiotensin II-induced [3H]adenosine release from in situ rat lung.
Topics: Adenosine; Anesthesia; Angiotensin II; Animals; Chromatography, Thin Layer; Hypertension; Lung; Male; Nephrectomy; Pulmonary Circulation; Rats; Rats, Inbred Strains; Renin; Saralasin | 1990 |
Remodeling of the rat right and left ventricles in experimental hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Collagen; Fibrosis; Heart Ventricles; Hemodynamics; Hypertension; Hypertension, Renovascular; Male; Rats; Rats, Inbred Strains; Staining and Labeling | 1990 |
Modulation of extracellular matrix by angiotensin II: stimulated glycoconjugate synthesis and growth in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arteriosclerosis; Cells, Cultured; Dose-Response Relationship, Drug; Extracellular Matrix; Glycoconjugates; Hypertension; Kinetics; Muscle Development; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR | 1990 |
Comparison of the acute hypotensive effects of renin inhibition, converting enzyme inhibition, and angiotensin II antagonism in rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Enalaprilat; Hypertension; Hypertension, Renal; Imidazoles; Losartan; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin; Time Factors | 1990 |
Enhanced cell proliferation in essential hypertension.
Topics: Angiotensin II; Animals; Blood; Cattle; Cell Division; Cells, Cultured; Fibroblasts; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Proto-Oncogenes; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Skin | 1990 |
Mitogenesis in cultured vascular smooth muscle cells from two rat models of hypertension in response to fetal calf serum and angiotensin II.
Topics: Angiotensin II; Animals; Cells, Cultured; Hypertension; Mitosis; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Thymidine | 1990 |
Effect of angiotensin II on plasma adenosine concentrations in the rat.
Topics: Adenosine; Anesthesia; Angiotensin II; Animals; Consciousness; Dose-Response Relationship, Drug; Hypertension; Infusions, Intravenous; Injections, Intraperitoneal; Kidney; Lung; Male; Rats; Rats, Inbred Strains; Renin | 1991 |
Effects of ramipril on arterial hemodynamics.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Blood Pressure; Blood Volume; Brachial Artery; Bridged Bicyclo Compounds; Carotid Arteries; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Ramipril; Renin; Vascular Resistance | 1991 |
Pressure natriuresis and angiotensin II in reduced kidney mass, salt-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Hypertension; Kidney; Natriuresis; Perfusion; Pressure; Renin; Sodium Chloride | 1992 |
Circadian variation of tumor blood flow in rat subcutaneous tumors and its alteration by angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Division; Circadian Rhythm; Hypertension; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Sarcoma, Experimental | 1992 |
Endothelin stimulated by angiotensin II augments contractility of spontaneously hypertensive rat resistance arteries.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Endothelins; Endothelium, Vascular; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Vascular Resistance; Vasoconstriction | 1992 |
Effects of angiotensin subtype 1 and subtype 2 receptor antagonists in normotensive versus hypertensive rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Infusions, Intravenous; Losartan; Mesentery; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1991 |
Fluctuations in tumor blood flow under normotension and the effect of angiotensin II-induced hypertension.
Topics: Anesthesia, Inhalation; Angiotensin II; Animals; Blood Pressure; Hypertension; Liver Neoplasms, Experimental; Male; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Regional Blood Flow; Sarcoma, Experimental; Time Factors | 1991 |
[Central norepinephrine and angiotensin II contents in the brain regions of spontaneously hypertensive rats (SHR) and the interaction between them].
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Hypertension; Norepinephrine; Oxidopamine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
Activation and measurement of plasma prorenin in the rat.
Topics: Adrenal Glands; Anesthetics; Angiotensin II; Animals; Blood Specimen Collection; Enzyme Activation; Enzyme Precursors; Freezing; Hypertension; Male; Rats; Rats, Inbred Strains; Renin; Trypsin | 1991 |
Effect of chronic treatment with clonidine and spironolactone on cold-induced elevation of blood pressure.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Clonidine; Cold Temperature; Drinking; Drug Therapy, Combination; Eating; Epinephrine; Hypertension; Kidney; Male; Norepinephrine; Organ Size; Rats; Rats, Inbred Strains; Renin; Spironolactone; Time Factors; Urination | 1991 |
Exaggerated response to electrical nerve stimulation of angiotensin II release in isolated perfused hind legs of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Electric Stimulation; Hindlimb; Hypertension; In Vitro Techniques; Male; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
Arachidonic acid does not share the antihypertensive properties of linoleic acid and fish oil omega-3 fatty acids in a model of angiotensin II-induced hypertension in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acid; Fatty Acids, Omega-3; Hypertension; Indomethacin; Linoleic Acid; Linoleic Acids; Male; Rats; Rats, Inbred Strains; Thromboxane B2 | 1991 |
Second Björn Folkow Award Lecture. The renin-angiotensin system: new surprises ahead.
Topics: Angiotensin II; Blood Pressure; Blood Vessels; Enzyme Precursors; Humans; Hypertension; Renal Artery Obstruction; Renin; Renin-Angiotensin System | 1991 |
Angiotensin II production in different vascular beds in hypertensive subjects.
Topics: Adult; Angiotensin II; Aorta; Blood Vessels; Forearm; Humans; Hypertension; Kidney; Leg; Liver; Middle Aged | 1991 |
Adenosine causes angiotensin II release in human forearm arterioles.
Topics: Adenosine; Adult; Angiotensin II; Arteries; Arterioles; Blood Volume; Dose-Response Relationship, Drug; Female; Forearm; Humans; Hypertension; Male; Middle Aged; Veins | 1991 |
[Effect of captopril on urinary 6-keto-PGF1 alpha, thromboxane B2 in inbred SHR rats].
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Captopril; Female; Hypertension; Male; Rats; Rats, Inbred SHR; Renin; Thromboxane B2 | 1991 |
[Endothelin in arterial hypertension].
Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Endothelins; Heart Failure; Humans; Hypertension; Radioimmunoassay; Reference Values; Renin | 1991 |
Angiotensin and thromboxane in genetically hypertensive rats: renal blood flow and receptor studies.
Topics: Angiotensin II; Animals; Hypertension; Kidney; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Receptors, Prostaglandin; Receptors, Thromboxane; Renal Circulation; Thromboxane A2 | 1991 |
[Relation between traditional Chinese medicine differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor in patients with essential hypertension].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Female; Humans; Hypertension; Male; Medicine, Chinese Traditional; Middle Aged; Renin | 1991 |
Does mild autonomic neuropathy affect atrial natriuretic factor regulation in diabetic hypertensive patients?
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Autonomic Nervous System Diseases; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Hypertension; Male; Middle Aged; Posture; Renin | 1991 |
Effects of tryptophan on the development of deoxycorticosterone acetate (DOCA)-induced hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiomegaly; Desoxycorticosterone; Diencephalon; Drinking; Eating; Female; Hypertension; Nephrectomy; Protein Binding; Rats; Rats, Inbred Strains; Serotonin; Sodium Chloride; Tryptophan | 1991 |
Role of angiotensin II receptor antagonism and converting enzyme inhibition in the progression and regression of cardiac hypertrophy in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Biphenyl Compounds; Bridged Bicyclo Compounds; Cardiomegaly; Constriction; Hypertension; Imidazoles; Losartan; Male; Ramipril; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles | 1991 |
Effect of plasma from patients with essential hypertension on vascular resistance in the isolated perfused rat kidney.
Topics: Adult; Angiotensin II; Animals; Blood Pressure; Chromatography, Gel; Female; Humans; Hypertension; In Vitro Techniques; Kidney; Male; Middle Aged; Molecular Weight; Nifedipine; Norepinephrine; Phentolamine; Rats; Rats, Inbred WKY; Saralasin; Sodium-Potassium-Exchanging ATPase; Vascular Resistance | 1991 |
Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Blotting, Northern; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Extracellular Matrix; Fibronectins; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; RNA, Messenger; Stimulation, Chemical; Time Factors | 1991 |
Enhanced response to growth factors and to angiotensin II of spontaneously hypertensive rat skin fibroblasts in culture.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; DNA; Fibroblasts; Growth Substances; Hypertension; Inositol Phosphates; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Skin; Stimulation, Chemical; Type C Phospholipases; Vasoconstrictor Agents | 1991 |
Angiotensin and cell growth: a link to cardiovascular hypertrophy?
Topics: Adrenal Cortex; Angiotensin II; Animals; Cell Division; Cell Line; Growth Substances; Humans; Hypertension; Muscle, Smooth, Vascular; Renin-Angiotensin System; Stimulation, Chemical | 1991 |
Ontogeny of renal renin release in spontaneously hypertensive rat and Wistar-Kyoto rat.
Topics: Aging; Angiotensin II; Animals; Hypertension; Isoproterenol; Kidney Cortex; Kidney Tubules, Proximal; Microvilli; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1991 |
The antihypertensive effect of calcitonin gene-related peptide in rats with norepinephrine- and angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Hemodynamics; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Vascular Resistance | 1991 |
Endothelin binding in brain of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Binding, Competitive; Brain; Endothelins; Hypertension; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cell Surface; Receptors, Endothelin | 1991 |
Alterations in cardiovascular responsiveness and adrenoceptor binding during catecholamine infusion hypertension in rats.
Topics: Angiotensin II; Animals; Aorta; Arginine Vasopressin; Blood Pressure; Hypertension; Infusions, Parenteral; Kinetics; Male; Muscle, Smooth, Vascular; Myocardium; Norepinephrine; Ornithine Decarboxylase; Pindolol; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Reference Values | 1991 |
Reversal of low dose angiotension hypertension by angiotensin receptor antagonists.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Infusions, Intravenous; Male; Rats; Rats, Inbred Strains; Saralasin | 1991 |
Changes in blood pressure and dipsogenic responsiveness to angiotensin II during chronic exposure of rats to cold.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Blood Pressure; Cold Temperature; Drinking; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System | 1991 |
Importance of chloride in the development of salt-induced angiotensin II hypertension in rats.
Topics: Angiotensin II; Animals; Chlorides; Citrates; Citric Acid; Hypertension; Male; Rats; Rats, Inbred Strains; Sodium Chloride | 1991 |
Measurement of individual plasma angiotensins in normal pregnancy and pregnancy-induced hypertension.
Topics: Adult; Angiotensin II; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Radioimmunoassay | 1991 |
Role of endothelium-derived prostanoid in angiotensin-induced vasoconstriction.
Topics: Acetylcholine; Analysis of Variance; Angiotensin II; Animals; Aorta; Aortic Coarctation; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Endothelins; Endothelium; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Pyridines; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction | 1991 |
Angiotensin II mediates hyperadrenergic activity evoked by sodium restriction in essential hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Diet, Sodium-Restricted; Heart Rate; Humans; Hypertension; Hypotension; Norepinephrine; Renin | 1991 |
Family history and pathophysiological mechanisms of primary hypertension. Studies in non-hypertensive young men with positive and negative family histories of hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Body Weight; Catecholamines; Cross-Sectional Studies; Fathers; Follow-Up Studies; Hemodynamics; Hormones; Humans; Hypertension; Kidney; Male; Phenylephrine; Potassium; Saline Solution, Hypertonic; Sodium; Water-Electrolyte Balance | 1991 |
Effects of induced hypertension on blood flow and capillary permeability in rats with experimental brain tumors.
Topics: Aminoisobutyric Acids; Angiotensin II; Animals; Antineoplastic Agents; Brain Neoplasms; Capillary Permeability; Cerebrovascular Circulation; Glioma; Hypertension; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1991 |
Angiotensin II induced phosphorylation of myosin light chain in vascular smooth muscle cells from spontaneously hypertensive and normotensive rats.
Topics: Angiotensin II; Animals; Aorta; Autoradiography; Cells, Cultured; Cerebral Arteries; Densitometry; Dose-Response Relationship, Drug; Electrophoresis; Hypertension; Lasers; Mesenteric Arteries; Muscle, Smooth, Vascular; Myosins; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
Effects of saralasin on arterial compliance in normotensive and hypertensive rats. Role of endothelium.
Topics: Angiotensin II; Animals; Arteries; Compliance; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; Potassium Cyanide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Saralasin | 1991 |
Fibronectin biosynthesis in the rat aorta in vitro. Changes due to experimental hypertension.
Topics: Age Factors; Angiotensin II; Animals; Aorta; Fibronectins; Hypertension; In Vitro Techniques; Male; Protein Biosynthesis; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta | 1991 |
Hyperactivation of phospholipase C does not support the enhanced proliferation of aortic smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Cell Division; Cells, Cultured; DNA; DNA Replication; Enzyme Activation; Epidermal Growth Factor; Gene Expression; Hypertension; Muscle, Smooth, Vascular; Oncogenes; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thymidine; Transcription, Genetic; Type C Phospholipases; Vasopressins | 1991 |
Impaired response to angiotensin II in type 1 (insulin-dependent) diabetes mellitus. Role of prostaglandins and sodium-lithium countertransport activity.
Topics: Adult; Albuminuria; Angiotensin II; Antiporters; Blood Pressure; Carrier Proteins; Diabetes Mellitus, Type 1; Erythrocytes; Female; Glomerular Filtration Rate; Humans; Hypertension; Indomethacin; Male; Potassium; Prostaglandins; Reference Values; Renal Circulation; Sodium; Vascular Resistance | 1991 |
Role of chloride in angiotensin II-induced salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Chlorides; Citrates; Citric Acid; Extracellular Space; Hypertension; Kidney; Male; Norepinephrine; Rats; Rats, Inbred Strains; Sodium Chloride; Sympathetic Nervous System | 1991 |
Effect of chronic dietary treatment with L-tryptophan on the development of cold-induced hypertension in rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Catecholamines; Cold Temperature; Diet; Hypertension; Male; Organ Size; Rats; Rats, Inbred Strains; Tryptophan | 1991 |
Antihypertensive effect of dietary calcium loading in angiotensin II-salt rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcitriol; Calcium, Dietary; Electrolytes; Epinephrine; Hypertension; Norepinephrine; Rats; Rats, Inbred Strains | 1991 |
Prediction of pregnancy-induced hypertensive disorders by angiotensin II sensitivity and supine pressor test.
Topics: Angiotensin II; Female; Humans; Hypertension; Posture; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular | 1991 |
Effect of delapril on the vascular angiotensin II release in isolated hind legs of the spontaneously hypertensive rat: evidence for potential relevance of vascular angiotensin II to the maintenance of hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Indans; Muscle, Smooth, Vascular; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System | 1991 |
Hormone and electrolyte changes in post-deoxycorticosterone salt hypertension in rats.
Topics: Adrenalectomy; Angiotensin II; Animals; Atrial Natriuretic Factor; Desoxycorticosterone; Drug Implants; Electrolytes; Hormones; Hypertension; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains; Renin | 1990 |
Suppression of the renin-angiotensin system induced by streptozotocin treatment in neonatal spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Humans; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin-Angiotensin System; Streptozocin | 1990 |
Differences in regional vascular sensitivity to endothelin-1 between spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Acetylcholine; Anesthesia; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Endothelins; Ganglionic Blockers; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitroprusside; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Renal Circulation; Splanchnic Circulation | 1990 |
Does enhanced sympathetic tone contribute to angiotensin II hypertension in rats?
Topics: Adrenergic alpha-Agonists; alpha-Methyltyrosine; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Ganglionic Blockers; Hemodynamics; Hypertension; Male; Methoxamine; Methyltyrosines; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Tyrosine 3-Monooxygenase; Vasoconstrictor Agents; Water-Electrolyte Balance | 1990 |
Angiotensin II levels in hypertensive and normotensive pregnancies.
Topics: Angiotensin II; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular | 1991 |
Roles of renal and vascular renin in spontaneous hypertension and switching of the mechanism upon nephrectomy. Lack of hypotensive effects of inhibition of renin, converting enzyme, and angiotensin II receptor blocker after bilateral nephrectomy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Enalapril; Hypertension; Hypotension; Imidazoles; Immunoglobulin G; Indans; Losartan; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renin; Tetrazoles; Time Factors | 1991 |
The antihypertensive mechanism of delapril, a newly developed converting enzyme inhibitor, is related to the suppression of vascular angiotensin II release in the spontaneously hypertensive rat.
Topics: Administration, Oral; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Hypertension; Indans; Male; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; Time Factors | 1991 |
Increased Ca2+ signaling after alpha-adrenoceptor activation in vascular hypertrophy.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Coarctation; Calcium; Fura-2; Hypertension; Hypertrophy; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred Strains; Signal Transduction | 1991 |
Therapeutic efficacy of two-route chemotherapy using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, combined with the angiotensin-II-induced hypertension method in a rat uterine tumor.
Topics: Angiotensin II; Animals; Blood Pressure; Carcinoma, Transitional Cell; Cisplatin; Female; Hypertension; Injections, Intra-Arterial; Injections, Intravenous; Rats; Rats, Inbred Strains; Thiosulfates; Tissue Distribution; Urinary Bladder Neoplasms; Uterine Neoplasms | 1991 |
Failure of acute saralasin to reverse chronic hypertension in fetal lambs.
Topics: Angiotensin II; Animals; Aorta; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Blood Volume; Epinephrine; Female; Fetal Diseases; Hypertension; Norepinephrine; Pregnancy; Saralasin; Sheep; Urine | 1991 |
Renal hemodynamics and the renin-angiotensin-aldosterone system in normotensive subjects with hypertensive and normotensive parents.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Child; Female; Hemodynamics; Humans; Hypertension; Male; Renal Circulation; Renin; Renin-Angiotensin System; Vascular Resistance | 1991 |
Angiotensin-induced growth related metabolism is activated in cultured smooth muscle cells from spontaneously hypertensive rats and Wistar-Kyoto rats.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; Extracellular Matrix; Hypertension; Muscle, Smooth, Vascular; Ornithine Decarboxylase; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1991 |
New developments in renin and hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cardiovascular System; Humans; Hypertension; Kidney; Renin; Renin-Angiotensin System | 1991 |
Platelet angiotensin II binding sites in normotensive and hypertensive women.
Topics: Adult; Angiotensin II; Blood Platelets; Cross-Sectional Studies; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Receptors, Angiotensin | 1991 |
Effect of chloride on renal blood flow in angiotensin II induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Chlorides; Hypertension; Kidney; Male; Rats; Rats, Inbred Strains; Renal Circulation; Sodium, Dietary | 1991 |
Calcium entry blockade and agonist-mediated forearm vasoconstriction in hypertensive patients. Difference between nicardipine and verapamil.
Topics: Angiotensin II; Forearm; Humans; Hypertension; Lower Body Negative Pressure; Nicardipine; Phentolamine; Propranolol; Vasoconstriction; Verapamil | 1991 |
Baroreflex function in chronically stressed borderline hypertensive rats.
Topics: Angiotensin II; Animals; Arousal; Blood Pressure; Electroshock; Female; Hypertension; Male; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex; Stress, Psychological | 1991 |
[The correlation of the indices of humoral immunity and of the activity of the renin-angiotensin-aldosterone system in hypertensive patients].
Topics: Adult; Aldosterone; Angiotensin II; Antibody Formation; Disease Susceptibility; Humans; Hypertension; Immunoglobulins; Male; Renin; Renin-Angiotensin System | 1991 |
Increased production of angiotensin II in the adrenal gland of stroke-prone spontaneously hypertensive rats with malignant hypertension.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin I; Angiotensin II; Animals; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Hypertension; Hypertension, Malignant; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin | 1991 |
Effects of slow-release nifedipine on water-sodium, uric acid, and calcium metabolism, and on aldosterone secretion in patients with essential hypertension.
Topics: Aldosterone; Angiotensin II; Calcium; Delayed-Action Preparations; Humans; Hypertension; Nifedipine; Sodium; Time Factors; Uric Acid; Water | 1990 |
[Effect of chronic enalapril treatment on prorenin, renin and sex hormones during the menstrual cycle in patients with essential hypertension].
Topics: Adult; Angiotensin II; Enalapril; Enzyme Precursors; Female; Gonadal Steroid Hormones; Humans; Hypertension; Menstrual Cycle; Ovulation; Pituitary Gland, Anterior; Renin; Renin-Angiotensin System | 1990 |
Effects of digoxin on blood pressure responses to norepinephrine, angiotensin II and vasopressin in conscious rats.
Topics: Angiotensin II; Animals; Blood Pressure; Digoxin; Drug Interactions; Hypertension; Natriuresis; Norepinephrine; Rats; Rats, Inbred Strains; Vasopressins | 1990 |
Effects of H-7 (protein kinase inhibitor) and phorbol ester on aortic strips from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Calcimycin; Calcium; Dinoprost; Hypertension; In Vitro Techniques; Isoquinolines; Lanthanum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phorbol Esters; Piperazines; Potassium Chloride; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
[Increase of the pressor response to angiotensin II in normal pregnancy. A sign of increasing blood volume more than decreasing vascular reactivity].
Topics: Adult; Analysis of Variance; Angiotensin II; Blood Pressure; Blood Volume; Body Weight; Female; Humans; Hypertension; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Pregnancy Trimester, Third | 1990 |
[Role of external calcium on the growth of aortic smooth muscle cells in SHR].
Topics: Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Hypertension; Mitosis; Muscle Development; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Verapamil | 1990 |
Contrasting effect of thromboxane synthase inhibitors and a thromboxane receptor antagonist on the development of angiotensin II-salt-induced hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; Male; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Sodium Chloride; Thromboxane A2; Thromboxane-A Synthase | 1990 |
[A study on dynamics of human atrial natriuretic polypeptide based on loading tests with angiotensin-II and NaCl in pregnancy induced hypertension].
Topics: Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; Hypertension; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Saline Solution, Hypertonic; Sodium | 1990 |
Effects of long-term increases in plasma ANP on angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output; Dogs; Glomerular Filtration Rate; Hypertension; Injections, Intravenous; Time Factors; Vascular Resistance | 1990 |
Flight influence on the plasma level of renin-angiotensin-aldosterone system and atrial natriuretic peptide.
Topics: Adult; Aerospace Medicine; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Humans; Hypertension; Male; Radioimmunoassay; Renin-Angiotensin System | 1990 |
Isolated myocardial cells: a new tool for the investigation of hypertensive heart disease.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Heart Rate; Hypertension; Isoproterenol; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains | 1990 |
Renal function in rats with angiotensin II-salt-induced hypertension: effect of thromboxane synthesis inhibition and receptor blockade.
Topics: Angiotensin II; Animals; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; Kidney; Male; Rats; Rats, Inbred Strains; Sodium, Dietary; Thromboxane A2; Thromboxane-A Synthase; Vascular Resistance | 1990 |
Abnormal calcium handling in vascular smooth muscle cells of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Caffeine; Calcium; Cytoplasm; Hypertension; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
The role of tissue renin-angiotensin systems in hypertension and effects of chronic converting-enzyme inhibition.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Captopril; Enalapril; Gene Expression Regulation; Heart; Hydralazine; Hypertension; Isoquinolines; Kidney; Lisinopril; Male; Quinapril; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrahydroisoquinolines | 1990 |
Altered responsiveness of proximal tubule fluid reabsorption of peritubular angiotensin II in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Kidney Tubules, Proximal; Natriuresis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Water-Electrolyte Balance | 1990 |
[The effect of parathormone on the reactivity of the cardiovascular system to angiotensin-2 in normotensive and spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dose-Response Relationship, Drug; Drug Interactions; Hemodynamics; Hypertension; Male; Parathyroid Hormone; Rats; Rats, Inbred SHR | 1990 |
Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blotting, Northern; Cells, Cultured; Hypertension; Mitogens; Mitosis; Muscle, Smooth, Vascular; Oncogenes; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Type C Phospholipases | 1990 |
Cardiovascular regulation during angiotensin converting enzyme inhibition with captopril in diabetes-associated hypertension.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diabetic Angiopathies; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sodium; Time Factors | 1990 |
Vascular hypertrophy, renin and blood pressure in the young spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Hypertension; Hypertrophy; Male; Mesenteric Arteries; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 1990 |
Free radical generation, lipid peroxidation and essential fatty acids in uncontrolled essential hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Endothelium, Vascular; Epoprostenol; Fatty Acids, Essential; Free Radicals; Humans; Hydrogen Peroxide; Hypertension; Lipid Peroxidation; Metoprolol; Neutrophils; Nitric Oxide; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate; Verapamil | 1990 |
Aminopeptidase-induced elevations and reductions in blood pressure in the spontaneously hypertensive rat.
Topics: Aminopeptidases; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Brain; Glutamyl Aminopeptidase; Humans; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
Angiotensin converting enzyme inhibitors reduce alcohol consumption: some possible mechanisms and important conditions for its therapeutic use.
Topics: Alcohol Drinking; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Dose-Response Relationship, Drug; Drinking; Hypertension; Male; Naltrexone; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1990 |
Nonpeptide angiotensin II receptor antagonists. IX. Antihypertensive activity in rats of DuP 753, an orally active antihypertensive agent.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Azoles; Blood Pressure; Hypertension; Imidazoles; Ligation; Losartan; Male; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Renal Artery; Renin; Tetrazoles | 1990 |
Chronic hyperinsulinemia and blood pressure regulation.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Diet; Dogs; Hyperinsulinism; Hypertension; Insulin; Sodium | 1990 |
Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Disease Models, Animal; Enzyme Precursors; Gene Expression; Hypertension; Kidney; Mice; Mice, Inbred DBA; Rats; Renin; Submandibular Gland; Transfection | 1990 |
[The efficacy of the captopril treatment of elderly hypertension patients].
Topics: Aged; Angiotensin II; Captopril; Drug Evaluation; Hemodynamics; Humans; Hypertension; Middle Aged; Renin | 1990 |
Biochemical correction in the syndrome of hypertension and hyperkalaemia by severe dietary salt restriction suggests renin-aldosterone suppression critical in pathophysiology.
Topics: Adult; Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Family Health; Humans; Hyperkalemia; Hypertension; Male; Renin; Syndrome | 1990 |
Enhanced DNA synthesis of cultured vascular smooth muscle cells from spontaneously hypertensive rats. Difference of response to growth factor, intracellular free calcium concentration and DNA synthesizing cell cycle.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cell Cycle; Cell Division; Cells, Cultured; DNA; Flow Cytometry; Growth Substances; Hypertension; Insulin; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thymidine | 1990 |
[Hypertension and prostanoids--the etiology and its implications for treatment].
Topics: Angiotensin II; Calcium; Captopril; Female; Humans; Hypertension; Indomethacin; Male; Prostaglandins | 1990 |
Efficacy of nifedipine to prevent systemic and renal vasoconstrictor effects of endothelin.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelins; Endothelium, Vascular; Hypertension; Hypotension; Male; Nifedipine; Norepinephrine; Peptides; Rats; Rats, Inbred Strains; Regression Analysis; Renal Circulation; Vasoconstriction | 1990 |
Angiotensin peptide regulation of fluid-phase endocytosis in brain microvessel endothelial cell monolayers.
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Endothelium, Vascular; Hypertension | 1990 |
Role of fluid volume retention in angiotensin II salt-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Volume; Body Weight; Cardiac Output; Dogs; Hemodynamics; Hypertension; Sodium Chloride; Splenectomy; Vascular Resistance | 1990 |
Effect of plasma from essential hypertensives on vascular tone of aortic strips, isolated perfused mesentery and isolated perfused kidney.
Topics: Adult; Angiotensin II; Animals; Aorta; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Mesenteric Arteries; Middle Aged; Nifedipine; Norepinephrine; Rats; Rats, Inbred WKY; Vasoconstriction | 1990 |
Salt sensitivity in hypertensive rats with angiotensin II administration.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride; Systole | 1990 |
Prediction of pregnancy-induced hypertensive disorders by angiotensin II sensitivity and supine pressor test.
Topics: Adult; Angiotensin II; Birth Weight; Blood Pressure; Female; Humans; Hypertension; Infant, Newborn; Pregnancy; Pregnancy Complications, Cardiovascular; Prospective Studies; Sensitivity and Specificity; Supination | 1990 |
Increased activity of the autonomic nervous system and increased sensitivity to angiotensin II infusion after therapy with recombinant human erythropoietin.
Topics: Angiotensin II; Autonomic Nervous System; Drug Resistance; Erythropoietin; Humans; Hypertension; Norepinephrine; Renal Dialysis | 1990 |
Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-term.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blood Vessels; Cardiovascular Physiological Phenomena; Hemodynamics; Hypertension; Indoles; Perindopril; Rats; Rats, Inbred SHR; Time Factors | 1990 |
Development of genetic hypertension. Is there a "critical phase"?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Humans; Hypertension; Rats; Rats, Inbred SHR; Time Factors | 1990 |
Effect of hypertension on fibronectin expression in the rat aorta.
Topics: Adipose Tissue, Brown; Age Factors; Angiotensin II; Animals; Aorta; Blotting, Northern; Blotting, Western; Collagen; Desoxycorticosterone; Disease Models, Animal; Fibronectins; Gene Expression; Hypertension; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred Strains; RNA, Messenger; Tropoelastin | 1990 |
Low-dose aspirin. II. Relationship of angiotensin II pressor responses, circulating eicosanoids, and pregnancy outcome.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Analysis of Variance; Angiotensin II; Aspirin; Blood Pressure; Chi-Square Distribution; Dinoprostone; Eicosanoids; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Pregnancy Trimester, Third; Thromboxane B2 | 1990 |
Chronic lymph flow and transcapillary fluid flux during angiotensin II hypertension.
Topics: Angiotensin II; Animals; Biological Transport; Blood Pressure; Blood Volume; Body Fluids; Capillaries; Dogs; Extracellular Space; Hypertension; Lymph; Proteins; Sulfates; Thoracic Duct; Time Factors | 1990 |
[Effect of the overactivated central renin-angiotensin system on the concentration of brain norepinephrine and epinephrine in stroke-prone spontaneously hypertensive rats and its significances].
Topics: Angiotensin II; Animals; Brain; Captopril; Epinephrine; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System | 1990 |
Effect of gender in centrally induced angiotensin II hypertension in dogs.
Topics: Angiotensin II; Animals; Arteries; Brain; Dogs; Female; Hemodynamics; Hypertension; Injections, Intraventricular; Male; Ouabain; Rubidium; Sex Characteristics; Tail | 1990 |
Measurement of immunoreactive angiotensin II levels in microdissected brain nuclei from developing spontaneously hypertensive and Wistar Kyoto rats.
Topics: Angiotensin II; Animals; Brain; Hypertension; Locus Coeruleus; Medulla Oblongata; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1990 |
Role of oxygen-derived free radicals in acute angiotensin II--induced hypertensive vascular disease in the rat.
Topics: Acute Disease; Angiotensin II; Animals; Arteries; Endothelium, Vascular; Free Radicals; Hypertension; Intestines; Male; Microscopy, Electron; Muscle, Smooth, Vascular; Oxygen; Rats; Rats, Inbred Strains | 1990 |
Salt-sensitive blood pressure and exaggerated vascular reactivity in the hypertension of diabetes mellitus.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diabetes Mellitus, Type 2; Diet, Sodium-Restricted; Humans; Hypertension; Middle Aged; Natriuresis; Sodium, Dietary | 1990 |
Prevention of salt angiotensin II hypertension by servo control of body water.
Topics: Angiotensin II; Animals; Blood Volume; Body Water; Dogs; Drug Administration Schedule; Hypertension; Male; Sodium Chloride | 1990 |
Decreased mesenteric vascular response to angiotensin II in portal hypertension.
Topics: Angiotensin II; Animals; Hypertension; Infusions, Intravenous; Male; Rabbits; Reference Values; Splanchnic Circulation; Vascular Resistance; Vasoconstriction | 1990 |
Depressor mechanism of enalapril in rats made hypertensive by norepinephrine or vasopressin.
Topics: Angiotensin II; Animals; Drug Therapy, Combination; Enalapril; Hypertension; Injections, Intraperitoneal; Male; Norepinephrine; Rats; Rats, Inbred Strains; Vasopressins | 1990 |
Vascular smooth muscle cells from the Milan hypertensive rat exhibit decreased functional angiotensin II receptors.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; Hypertension; Muscle, Smooth, Vascular; Potassium; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Sodium; Type C Phospholipases | 1990 |
Effect of age on response of secondary hypertension to specific treatment.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Pressure; Humans; Hydrocortisone; Hypertension; Hypertension, Renovascular; Hypothyroidism; Middle Aged | 1990 |
Modification of tumor blood flow and enhancement of therapeutic effect of ACNU on experimental rat gliomas with angiotensin II.
Topics: Angiotensin II; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Glioma; Hypertension; Nimustine; Rats; Rats, Inbred Strains | 1990 |
Role of aldosterone in angiotensin II-induced hypertension in rats.
Topics: Aldosterone; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension; Infusions, Intravenous; Male; Rats; Rats, Inbred Strains; Sodium | 1990 |
Exaggerated renal vascular reactivity to angiotensin and thromboxane in young genetically hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Hypertension; Indomethacin; Kidney; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regression Analysis; Renal Circulation; Thromboxane A2; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation | 1990 |
Metabolism and production of angiotensin I in different vascular beds in subjects with hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Male; Middle Aged; Renin; Tissue Distribution | 1990 |
Decreased angiotensin II receptors in subfornical organ of spontaneously hypertensive rats after chronic antihypertensive treatment with enalapril.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Enalapril; Hypertension; Male; Neurosecretory Systems; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Subfornical Organ; Vasomotor System | 1990 |
Baroreceptor reflex in elderly essential hypertensives: effect of chronic inhibition of angiotensin converting enzyme.
Topics: Adult; Age Factors; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Heart Rate; Humans; Hypertension; Middle Aged; Pressoreceptors; Reflex; Renin | 1990 |
Why use angiotensin converting enzyme inhibitors to lower blood pressure?
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Captopril; Diuretics; Drug Therapy, Combination; Humans; Hypertension; Male; Renin; Renin-Angiotensin System; Sodium | 1985 |
Arterial blood-pressure change and endogenous circulating substance P in man.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Hypotension; Male; Middle Aged; Pressoreceptors; Reflex; Substance P; Trimethaphan | 1985 |
Excitation-contraction coupling in hypertrophied myocardium.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Epinephrine; Heart; Hypertension; Hypertension, Renal; Male; Myocardial Contraction; Myocardium; Prazosin; Protein Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1985 |
Increased cardiovascular responses to norepinephrine and calcium antagonists in essential hypertension compared with normotension in humans.
Topics: Adult; Angiotensin II; Calcium Channel Blockers; Diltiazem; Hemodynamics; Humans; Hypertension; Male; Nifedipine; Norepinephrine; Propranolol | 1985 |
In vivo erythrocyte sodium concentration in human hypertension is reduced, not increased.
Topics: Angiotensin II; Blood Pressure; Erythrocytes; Humans; Hypertension; Ion Channels; Male; Norepinephrine; Potassium; Sodium | 1986 |
Changes in the pathophysiologic profile of blood pressure determinants during short-term enalapril administration.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Dose-Response Relationship, Drug; Drug Administration Schedule; Enalapril; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Regional Blood Flow; Renal Circulation; Renin; Sodium; Time Factors | 1986 |
Enalapril and the kidney: renal vasodilation and natriuresis due to the inhibition of angiotensin II formation.
Topics: Administration, Oral; Adult; Angiotensin II; Body Weight; Enalapril; Enalaprilat; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Middle Aged; Natriuresis; Potassium; Renal Circulation; Renin; Sodium; Vasodilation | 1986 |
Clinical studies with a vascular vasopressin antagonist.
Topics: Angiotensin II; Arginine Vasopressin; Heart Failure; Hemodynamics; Humans; Hypertension; Smoking; Steam Bath; Vasopressins | 1986 |
Exaggerated renal vasodilator response to calcium entry blockade in first-degree relatives of essential hypertensive subjects.
Topics: Acetylcholine; Adult; Angiotensin II; Diltiazem; Humans; Hypertension; Ion Channels; Middle Aged; Renal Artery; Renal Circulation | 1987 |
Vascular angiotensin conversion in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Forearm; Humans; Hypertension; Kinetics; Peptidyl-Dipeptidase A; Pyrroles; Ramipril; Reference Values; Regional Blood Flow; Renin | 1986 |
Effects of ketanserin on hemodynamics and baroreflex effects in conscious spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Atropine; Hemodynamics; Hypertension; Ketanserin; Nitroprusside; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex | 1987 |
The renal antihypertensive effect of angiotensin I converting enzyme inhibitors.
Topics: Acute Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Female; Heart Rate; Hypertension; Indomethacin; Kidney; Norepinephrine; Rabbits; Saralasin | 1987 |
Antihypertensive, enzymatic, and hormonal activity of cilazapril, a new angiotensin-converting enzyme inhibitor in patients with mild to moderate essential hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Female; Humans; Hypertension; Male; Middle Aged; Pyridazines; Renin | 1988 |
Nifedipine does not blunt the aldosterone and cardiovascular response to angiotensin II and potassium infusion in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Drug Interactions; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Nifedipine; Potassium; Renin | 1988 |
Hormonal and renal responses to oral once-daily calcium entry blocker in normotensive and hypertensive persons.
Topics: Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Dopamine; Epinephrine; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Nifedipine; Norepinephrine; Renin | 1988 |
Changes in sensitivity to angiotensin II in platelets.
Topics: Administration, Oral; Adult; Angiotensin II; Blood Platelets; Blood Pressure; Calcium; Captopril; Female; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Nifedipine; Saralasin | 1987 |
Vasoconstriction and hypersensitivity to vasoactive substances after acute volume expansion in dogs.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Volume; Cardiac Output; Dextrans; Dogs; Epinephrine; Heart Rate; Hypertension; Natriuresis; Norepinephrine; Renin; Vascular Resistance; Vasoconstriction; Vasopressins | 1988 |
Age dependence of the pressor sensitivity to noradrenaline and angiotensin II during calcium channel blockade in hypertensive patients.
Topics: Aged; Aged, 80 and over; Aging; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine | 1988 |
Role of kallikrein-kinin system in the hypotensive mechanisms of converting enzyme inhibitors in essential hypertension.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bridged Bicyclo Compounds; Humans; Hypertension; Kallikreins; Kinins; Middle Aged; Proline; Radioimmunoassay; Ramipril; Renin; Sodium | 1989 |
Effects of angiotensin II blockade on the responses of the pituitary-adrenal axis to corticotropin-releasing factor in humans.
Topics: Angiotensin II; Captopril; Corticotropin-Releasing Hormone; Humans; Hypertension; Pituitary-Adrenal System | 1987 |
Reduced plasma noradrenaline during angiotensin II-induced acute hypertension in man.
Topics: Acute Disease; Adult; Aged; Angiotensin II; Blood Pressure; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine | 1985 |
Abnormal glomerular and tubular function during angiotensin converting enzyme inhibition in renovascular hypertension evaluated by the lithium clearance method.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Female; Glomerular Filtration Rate; Humans; Hydrostatic Pressure; Hypertension; Hypertension, Renovascular; Kidney Tubules; Lithium; Male; Middle Aged | 1989 |
Effects of calcium antagonists and nitroglycerin on atrial natriuretic peptide in normal subjects and patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; Nitroglycerin; Renin-Angiotensin System | 1989 |
Atrial natriuretic peptide and exaggerated natriuresis during acute hypertonic volume expansion in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Volume; Dinoprostone; Female; Glomerular Filtration Rate; Humans; Hypertension; Lithium; Male; Middle Aged; Natriuresis; Saline Solution, Hypertonic; Sodium | 1989 |
Atrial natriuretic peptide and angiotensin II binding sites in cerebral capillaries of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Binding Sites; Blood Pressure; Capillaries; Cerebral Cortex; Hypertension; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole | 1989 |
Role of TXA2 in the pathogenesis of severe angiotensin II-salt hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Kidney Cortex; Muscle, Smooth, Vascular; Rats; Reference Values; Sodium, Dietary; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1989 |
Converting enzyme inhibition specifically prevents the development and induces regression of cardiac hypertrophy in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bridged Bicyclo Compounds; Cardiomegaly; Dihydralazine; Hypertension; Male; Nifedipine; Ramipril; Rats; Rats, Inbred Strains | 1989 |
[Pathogenesis and treatment of hypertension during pregnancy].
Topics: Angiotensin II; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins | 1989 |
On the pathogenesis of arterial blood pressure elevation early in the course of diabetic nephropathy.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Extracellular Space; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Plasma Volume; Renin; Renin-Angiotensin System | 1989 |
Significance of kallikrein-kinin and renin-angiotensin systems in the hypotensive mechanism of angiotensin-I converting enzyme inhibitors in essential hypertensives.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Captopril; Diuresis; Heart Rate; Humans; Hypertension; Kallikreins; Kinins; Ramipril; Renin-Angiotensin System | 1989 |
Effects of cilazapril on renal function and hormones in hypertensive patients with renal disease.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cilazapril; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Pyridazines; Renal Circulation; Renin | 1989 |
Study of the pathogenesis of cardiac hypertrophy--biochemical differences of cultured heart cells from normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Hypertension; Isoproterenol; Leucine; Myocardium; Protein Biosynthesis; Proteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stimulation, Chemical; Uridine | 1989 |
Enalapril prevents stroke and kidney dysfunction in salt-loaded stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebrovascular Disorders; Enalapril; Glomerular Filtration Rate; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Sodium Chloride | 1989 |
Chronic MK421 fails to modify evolution of hypertension in neonatally coarcted pups.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Aortic Coarctation; Blood Pressure; Dogs; Enalapril; Extracellular Space; Female; Glomerular Filtration Rate; Hypertension; Male | 1989 |
Metabolism of angiotensin peptides by neuronal and glial cultures from rat brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Hypertension; Kinetics; Neuroglia; Neurons; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1989 |
Spontaneously hypertensive rat vascular smooth muscle cells in culture exhibit increased growth and Na+/H+ exchange.
Topics: Amiloride; Angiotensin II; Animals; Carrier Proteins; Cell Division; Cells, Cultured; DNA; Hydrogen-Ion Concentration; Hypertension; Muscle, Smooth, Vascular; Nigericin; Protons; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 1989 |
Prolonged converting enzyme inhibition in non-modulating hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Enalapril; Humans; Hypertension; p-Aminohippuric Acid; Renal Circulation; Renin; Renin-Angiotensin System; Time Factors | 1989 |
Angiotensin II and atrial natriuretic factor-binding sites in various tissues in hypertension: comparative receptor localization and changes in different hypertension models in the rat.
Topics: Adrenal Glands; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Brain; Brain Stem; Disease Models, Animal; Hypertension; Hypertension, Renovascular; Kidney Glomerulus; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Reference Values; Renin | 1989 |
Enhanced responsiveness to angiotensin II in vascular smooth muscle cells from spontaneously hypertensive rats is not associated with alterations in protein kinase C.
Topics: Angiotensin II; Animals; Cells, Cultured; Enzyme Activation; Hydrogen-Ion Concentration; Hypertension; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate | 1989 |
Arterial hypertension as a paraneoplastic phenomenon in hepatocellular carcinoma.
Topics: Adult; Angiotensin II; Carcinoma, Hepatocellular; Child; Humans; Hypertension; Liver Neoplasms; Male; Paraneoplastic Syndromes; Renin | 1989 |
Antihypertensive properties of linoleic acid and fish oil omega-3 fatty acids independent of the prostaglandin system.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Eicosapentaenoic Acid; Fish Oils; Hypertension; Indomethacin; Linoleic Acids; Male; Muscle Contraction; Phenylephrine; Prostaglandins; Rats; Rats, Inbred Strains; Renin | 1989 |
Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin II; Animals; Blood Pressure; Dinoprostone; Hypertension; Male; Methoxamine; Phenoxybenzamine; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regression Analysis; Splanchnic Nerves; Sympathetic Nervous System; Thromboxane B2 | 1989 |
Alterations in cerebrospinal fluid angiotensin II by sodium intake in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Endopeptidases; Female; Humans; Hypertension; Male; Middle Aged; Renin; Sodium | 1989 |
Enhanced slow-pressor response to angiotensin II in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension; Kidney; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Synaptic Transmission | 1989 |
Role of the endogenous angiotensin II in the antihypertensive effect of MK 421 in rats made hypertensive by norepinephrine or vasopressin.
Topics: Angiotensin II; Animals; Blood Pressure; Enalapril; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Reference Values; Vasopressins | 1989 |
Antihypertensive contribution of sodium depletion and the sympathetic axis during chronic angiotensin II converting enzyme inhibition.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Cardiovascular Physiological Phenomena; Diet, Sodium-Restricted; Enalapril; Female; Humans; Hypertension; Isoproterenol; Male; Middle Aged; Norepinephrine; Peptidyl-Dipeptidase A; Random Allocation; Single-Blind Method; Sodium; Time Factors | 1989 |
Effect of enalapril on aortic smooth muscle cell polyploidy in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Enalapril; Flow Cytometry; Hypertension; Male; Muscle, Smooth, Vascular; Polyploidy; Rats; Rats, Inbred SHR; Regression Analysis | 1989 |
Enhanced presynaptic facilitation of vascular adrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Captopril; Female; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Saralasin; Splanchnic Circulation; Sympathetic Nervous System; Synaptic Transmission | 1989 |
Pressor responsiveness in essential hypertension and the effects of treatment with an alpha blocker, calcium antagonist or ACE inhibitor.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Phenylephrine; Reference Values | 1989 |
Hemodynamics and blood volume in angiotensin II salt-dependent hypertension in dogs.
Topics: Angiotensin II; Animals; Blood Volume; Diet, Sodium-Restricted; Dogs; Hemodynamics; Hypertension; Infusions, Intravenous; Male; Sodium Chloride | 1989 |
Acute aortic coarctation hypertension: role of vasopressin and angiotensin II.
Topics: Acute Disease; Angiotensin II; Animals; Aortic Coarctation; Arginine Vasopressin; Blood Pressure; Carotid Arteries; Heart Rate; Hypertension; Male; Rats; Rats, Inbred Strains; Saralasin; Vasopressins | 1989 |
Quantitative contribution of systemic vascular autoregulation in acute hypertension in conscious dogs.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Dogs; Female; Hemodynamics; Homeostasis; Hypertension; Male; Norepinephrine; Vascular Resistance | 1989 |
[Prevention and countermeasures in kidney diseases complicated by hypertension].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Humans; Hypertension; Nephrosclerosis; Platelet-Derived Growth Factor | 1989 |
Estimation of regional metabolism and production of angiotensins in hypertensive subjects.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensins; Arteries; Blood; Humans; Hypertension; Infusions, Intravenous; Iodine Radioisotopes; Middle Aged; Veins | 1989 |
Plasma kinin levels in experimental hypertension in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Desoxycorticosterone; Hypertension; Kinins; Male; Rats; Rats, Inbred Strains; Reference Values; Sodium, Dietary | 1989 |
[The functional organization of autoregulation of local cerebral blood flow in spontaneously hypertensive rats in ontogeny].
Topics: Adenosine Triphosphate; Aging; Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Cerebrovascular Circulation; Electrodes, Implanted; Homeostasis; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1989 |
Angiotensin-mediated renin suppression is altered in non-modulating hypertension.
Topics: Adult; Age Factors; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Female; Humans; Hypertension; Male; Renin | 1989 |
Altered vascular reactivity in sickle hemoglobinopathy. A possible protective factor from hypertension.
Topics: Adult; Anemia, Sickle Cell; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Disease Susceptibility; Female; Hemodynamics; Humans; Hypertension; Male; Norepinephrine; Plethysmography; Renin; Sodium | 1989 |
Modulation of urinary kallikrein and plasma renin activities does not affect established hypertension in the fawn-hooded rat.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kallikreins; Potassium; Rats; Rats, Inbred SHR; Renin; Sodium | 1989 |
Renin regulation in type II diabetes mellitus: influence of dietary sodium.
Topics: Aged; Angiotensin II; Chronic Disease; Creatinine; Diabetes Mellitus, Type 2; Humans; Hypertension; Middle Aged; Potassium; Renin; Renin-Angiotensin System; Sodium; Sodium, Dietary; Time Factors | 1989 |
Dietary sodium restriction and the renin-angiotensin system in young spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Diet, Sodium-Restricted; Hypertension; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System | 1989 |
Role of the renin-angiotensin system in hypertension during reduced uteroplacental perfusion pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Dogs; Female; Hypertension; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Renin; Renin-Angiotensin System; Uterus | 1989 |
Brain angiotensin II and baroreceptor reflex function in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Drinking; Hypertension; Injections, Intraventricular; Male; Nitroprusside; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Reflex | 1989 |
Effects of salt, prostaglandin, and captopril on vascular responsiveness in essential hypertension.
Topics: Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Prostaglandins; Sodium, Dietary; Vascular Resistance | 1989 |
Characteristics of pressor response to endothelin in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Endothelins; Hypertension; Indomethacin; Nicardipine; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Saralasin; Time Factors; Vasoconstrictor Agents | 1989 |
Evaluation of anterior pituitary function in hypertensive patients following inhibition of angiotensin II generation.
Topics: Adult; Angiotensin II; Captopril; Humans; Hypertension; Insulin; Male; Middle Aged; Pituitary Function Tests; Pituitary Gland, Anterior; Pituitary Hormones, Anterior | 1989 |
Plasma angiotensins, renin, and blood pressure during acute renin inhibition by CGP 38 560A in hypertensive patients.
Topics: Adult; Angiotensin II; Blood Pressure; Captopril; Humans; Hypertension; Middle Aged; Oligopeptides; Renin; Renin-Angiotensin System | 1989 |
Renin inhibition with A-64662: effect on blood pressure and hormonal response in man.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Dipeptides; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Hypertension; Injections, Intravenous; Renin; Time Factors | 1989 |
The area postrema and the hypertensive effect of angiotensin.
Topics: Angiotensin II; Animals; Cats; Cerebral Ventricles; Dose-Response Relationship, Drug; Female; Hypertension; Injections, Intraventricular; Male | 1989 |
Autoregulation of cochlear blood flow in normotensive and spontaneously hypertensive rats following intracerebroventricularly mediated adjustment of blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Cochlea; Homeostasis; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Regional Blood Flow | 1989 |
Role of afterload in progression of dilated cardiomyopathy--evaluation with force-velocity relation.
Topics: Adult; Aged; Angiotensin II; Cardiomyopathy, Alcoholic; Cardiomyopathy, Dilated; Echocardiography; Female; Follow-Up Studies; Heart; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Myocarditis; Time Factors | 1989 |
Baroreceptor sensitivity in prehypertensive young adults.
Topics: Adult; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Exercise; Heart Rate; Humans; Hypertension; Lower Body Negative Pressure; Nitroprusside; Norepinephrine; Pressoreceptors; Vascular Resistance | 1989 |
Vasopressin in neuronal cultures from neonatal rat brain.
Topics: Angiotensin II; Animals; Animals, Newborn; Arginine Vasopressin; Brain; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Hypertension; Neurons; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1989 |
Evidence for heritability of non-modulating essential hypertension.
Topics: Angiotensin II; Diet, Sodium-Restricted; Humans; Hypertension; Medical Records; Reference Values; Renal Circulation | 1989 |
Leucine aminopeptidase M-induced reductions in blood pressure in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Hypertension; Injections, Intraventricular; Leucyl Aminopeptidase; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1989 |
Renal vasomotion in essential hypertension: influence of vasodilators.
Topics: Angiotensin II; Humans; Hypertension; Norepinephrine; Renal Circulation; Vasodilator Agents; Vasomotor System | 1989 |
The role of dopamine in nonmodulating hypertension.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Dopamine; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Infusions, Intravenous; Male; Metoclopramide; Middle Aged; Natriuresis; Sodium | 1989 |
Cadmium-induced hypertension in rats.
Topics: Acetylcholine; Adrenalectomy; Angiotensin II; Animals; Blood Pressure; Body Weight; Cadmium; Calcium Channel Blockers; Female; Hindlimb; Hypertension; Isoproterenol; Norepinephrine; Rats; Rats, Inbred Strains; Regional Blood Flow; Sympathectomy, Chemical; Vascular Resistance | 1989 |
Increased blood pressure induced by central application of aminopeptidase inhibitors is angiotensinergic-dependent in normotensive and hypertensive rat strains.
Topics: Aminopeptidases; Angiotensin II; Animals; Anti-Bacterial Agents; Blood Pressure; Brain; Enzyme Inhibitors; Hypertension; Leucine; Male; Oligopeptides; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin | 1989 |
Central action of sodium chloride on whole body pressor responsiveness in the DOCA-treated rat.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Sodium Chloride | 1989 |
Effect of chronic dietary treatment with L-tryptophan on the maintenance of hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain Chemistry; Diet; Dopamine; Drinking; Eating; Epinephrine; Hypertension; Male; Norepinephrine; Potassium; Rats; Rats, Inbred SHR; Sodium; Time Factors; Tryptophan | 1989 |
Lack of evidence of a vasodepressor role for relaxin in spontaneously hypertensive and normotensive pregnant rats.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Hypertension; Norepinephrine; Ovariectomy; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Relaxin | 1989 |
Fetal vascular responses to maternal nicardipine administration in the hypertensive ewe.
Topics: Angiotensin II; Animals; Blood Gas Analysis; Female; Fetal Blood; Fetal Heart; Hypertension; Nicardipine; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Renal Circulation; Sheep; Vascular Resistance | 1989 |
Placental vascular responses to nicardipine in the hypertensive ewe.
Topics: Angiotensin II; Animals; Female; Hypertension; Nicardipine; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Renal Circulation; Sheep; Uterus; Vascular Resistance; Vasoconstriction | 1989 |
Humoral effects of ACE-inhibition.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Drug Evaluation; Enalapril; Female; Humans; Hypertension; Male; Norepinephrine; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Time Factors | 1987 |
Effect of a renin-system inhibitor on blood-vessel adaptation in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blood Vessels; Body Weight; Enalapril; Hematocrit; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Rubidium | 1987 |
Effect of sodium depletion on pressor responsiveness in ACTH-induced hypertension in man.
Topics: Adrenocorticotropic Hormone; Adult; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Infusions, Intravenous; Male; Phenylephrine | 1987 |
Modification of the haemodynamic effects of ACTH by angiotensin II in sheep.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Drug Interactions; Female; Hemodynamics; Hypertension; Sheep; Water-Electrolyte Balance | 1987 |
Effect of atrial natriuretic factor on aldosterone and its precursor steroid production in adrenal zona glomerulosa cells from spontaneously hypertensive rats.
Topics: 18-Hydroxycorticosterone; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Corticosterone; Hypertension; Male; Peptide Fragments; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium | 1987 |
Constricting and stiffening action of atropine on aortic response to angiotensin in dogs.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Atropine; Dogs; Female; Hypertension; Male; Muscle, Smooth, Vascular; Propranolol; Receptors, Adrenergic, beta; Receptors, Muscarinic; Vascular Resistance | 1988 |
Captopril and the response to stress in the spontaneously hypertensive rat.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Blood Pressure; Captopril; Corticosterone; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin-Angiotensin System; Stress, Physiological; Vasopressins | 1988 |
Enalapril and atenolol in essential hypertension: attenuation of hypotensive effects in combination.
Topics: Aldosterone; Angiotensin II; Atenolol; Atrial Natriuretic Factor; Drug Interactions; Drug Therapy, Combination; Enalapril; Heart Rate; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin | 1988 |
Angiotensin-responsive aldosterone-producing adenoma masquerades as idiopathic hyperaldosteronism (IHA: adrenal hyperplasia) or low-renin essential hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Dexamethasone; Diagnosis, Differential; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Posture; Renin | 1987 |
Captopril versus enalapril: a comparison of 24 h humoral and hypotensive effects.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Captopril; Enalapril; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin | 1987 |
[Receptors for vasoactive peptides in experimental hypertension and cardiac insufficiency].
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Heart Failure; Humans; Hypertension; Receptors, Angiotensin; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Receptors, Vasopressin; Vasopressins | 1988 |
Isoform-specific modulation of Na+, K+-ATPase alpha-subunit gene expression in hypertension.
Topics: Angiotensin II; Animals; Cardiomegaly; Desoxycorticosterone; Heart Ventricles; Hypertension; Isoenzymes; Rats; RNA, Messenger; Sodium-Potassium-Exchanging ATPase | 1988 |
Renal alpha 1-adrenergic receptor response coupling in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Carbachol; Hypertension; Inositol Phosphates; Kidney; Kidney Cortex; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Serotonin; Type C Phospholipases; Yohimbine | 1988 |
The effects of coarctation hypertension upon vascular inositol phospholipid hydrolysis in Wistar rats.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Female; Hydrolysis; Hypertension; Ligation; Phosphatidylinositols; Rats; Rats, Inbred Strains; Renin | 1988 |
[Ex vivo and in vitro effects of trandolapril on the efflux of 22Na from the caudal artery of the SHR rat. Inhibition of vascular angiotensin II production].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Cell Membrane; Enalapril; Hypertension; Indoles; Male; Ouabain; Rats; Rats, Inbred SHR; Saralasin; Sodium; Sodium Radioisotopes; Tail | 1988 |
Hypertension in pseudohypoparathyroidism type I.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Catecholamines; Child; Female; Humans; Hydrocortisone; Hypertension; Male; Obesity; Parathyroid Hormone; Posture; Pseudohypoparathyroidism; Renin | 1988 |
Renin-angiotensin modulation of sympathetic reflex function in essential hypertension and in the elderly.
Topics: Adult; Aged; Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Double-Blind Method; Enalapril; Heart Rate; Humans; Hypertension; Pyridazines; Random Allocation; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1988 |
Effect of chronic inhibition of angiotensin converting enzyme on baroreceptor reflex in essential hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Enalapril; Humans; Hypertension; Middle Aged; Norepinephrine; Pressoreceptors; Reflex | 1988 |
Severe hypertension with absent secondary sex characteristics due to partial deficiency of steroid 17 alpha-hydroxylase activity.
Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Dexamethasone; Female; Furosemide; Humans; Hypertension; Hypogonadism; Steroid Hydroxylases | 1987 |
[Basic and clinical studies of angiotensin II pressor responsiveness in pregnancy-induced-hypertension].
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Adult; Angiotensin II; Animals; Blood Pressure; Calcium; Eicosapentaenoic Acid; Estrogens; Female; Humans; Hypertension; Male; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Rabbits; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Stimulation, Chemical; Thromboxane B2 | 1988 |
Neurohumoral contributions to chronic angiotensin-induced hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Pressure; Blood Vessels; Electric Stimulation; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Hypertension; Injections, Intraventricular; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin; Spinal Cord; Sympathectomy, Chemical | 1986 |
Does vasopressin sustain blood pressure in conscious spontaneously hypertensive rats?
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasopressins; Water Deprivation | 1986 |
Hemodynamic effects of nifedipine in hypertension in the presence of elevated angiotensin-II and beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Renin-Angiotensin System; Vascular Resistance | 1986 |
Does angiotensin-II protect against strokes?
Topics: Angiotensin II; Bendroflumethiazide; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular Disorders; Homeostasis; Humans; Hypertension; Propranolol | 1986 |
Brain renin angiotensin system contributes to the salt-induced enhancement of hypertension in SHR.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Dose-Response Relationship, Drug; Hexamethonium; Hexamethonium Compounds; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Sodium Chloride; Time Factors | 1986 |
Development of angiotensin II-sensitive OVLT neurons in SHR and WKY rats.
Topics: Action Potentials; Aging; Angiotensin II; Animals; Glutamates; Glutamic Acid; Hypertension; Hypothalamus; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1988 |
[Interaction of chronic inhibition of the angiotensin-converting enzyme and the sympathetic system: effect of added sodium chloride load].
Topics: Adrenal Glands; Angiotensin II; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Epinephrine; Hypertension; Male; Myocardium; Ramipril; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium, Dietary; Sympathetic Nervous System; Tyrosine 3-Monooxygenase; Water-Electrolyte Balance | 1988 |
Trigeminovascular fibers increase blood flow in cortical gray matter by axon reflex-like mechanisms during acute severe hypertension or seizures.
Topics: Angiotensin II; Animals; Axons; Bicuculline; Blood Pressure; Cats; Cerebrovascular Circulation; Female; Ganglionectomy; Hypercapnia; Hypertension; Male; Organ Specificity; Periaqueductal Gray; Reference Values; Reflex; Seizures; Trigeminal Nerve | 1989 |
Does chronic hyperinsulinemia cause hypertension?
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Chronic Disease; Dogs; Hyperinsulinism; Hypertension; Natriuresis; Obesity | 1989 |
Chronic hypotensive effects of verapamil in angiotensin hypertension are steroid independent.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Chronic Disease; Dogs; Drug Evaluation, Preclinical; Hypertension; Kidney; Male; Verapamil; Water-Electrolyte Balance | 1989 |
Blunted responses to vasoconstrictors in mesenteric vasculature but not in portal vein of spontaneously hypertensive rats treated with relaxin.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Female; Hypertension; Mesenteric Arteries; Norepinephrine; Portal Vein; Rats; Rats, Inbred SHR; Relaxin; Vasoconstriction; Vasoconstrictor Agents | 1989 |
Neuropeptide action in nucleus tractus solitarius: angiotensin specificity and hypertensive rats.
Topics: Angiotensin II; Angiotensins; Animals; Blood Pressure; Brain Stem; Heart Rate; Hypertension; Male; Microinjections; Nerve Tissue Proteins; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Vasopressin; Species Specificity; Vasopressins | 1985 |
Effect of atrial natriuretic factor on angiotensin II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Diet; Hormones; Hypertension; Male; Rats; Rats, Inbred Strains; Sodium Chloride | 1986 |
[Protective effects of Ginkgo biloba extract on the early rupture of the hemato-encephalic barrier in the rat].
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hypertension; Male; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Rupture, Spontaneous; Trees | 1986 |
Cardiovascular, renal, and endocrine response to atrial natriuretic peptide in angiotensin II mediated hypertension.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Dogs; Female; Hemodynamics; Hormones; Hypertension; Kidney; Male; Natriuresis; Renal Circulation; Vasoconstriction | 1986 |
[Effect of atriopeptin on the plasma renin-angiotensin system in rats].
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Hypertension; Male; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System | 1986 |
Effects of angiotensin and noradrenaline on atrial natriuretic peptide levels in man.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Clonidine; Humans; Hypertension; Infusions, Intravenous; Middle Aged; Norepinephrine; Pheochromocytoma | 1987 |
Plasma levels of human atrial natriuretic peptide in patients with hypertensive diseases.
Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Cross Reactions; Diet, Sodium-Restricted; Humans; Hypertension; Plasma Volume; Radioimmunoassay; Renin | 1987 |
Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats.
Topics: 5-Hydroxytryptophan; Administration, Cutaneous; Angiotensin II; Animals; Cardiomegaly; Catecholamines; Desoxycorticosterone; Female; Hypertension; Infusion Pumps; Kidney Concentrating Ability; Nephrectomy; Rats; Rats, Inbred Strains; Sodium, Dietary | 1987 |
Atrial natriuretic factor in essential hypertension and adrenal disorders.
Topics: Adrenal Gland Diseases; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Vasoconstriction | 1988 |
Control of sodium excretion: atrial natriuresis and mineralocorticoid escape: some new aspects.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Denervation; Dogs; Heart; Hypertension; Mineralocorticoids; Natriuresis; Renin | 1987 |
Antihypertensive and hormonal effects of PN 200-110, a new calcium-channel blocker, in essential hypertension.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Dinoprostone; Female; Hormones; Humans; Hypertension; Isradipine; Male; Middle Aged; Oxadiazoles; Prostaglandins E; Renin; Vascular Resistance | 1987 |
Pharmacokinetics of single and consecutive doses of cilazapril and its depressor effects in patients with essential hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Aged; Osmolar Concentration; Pulse; Pyridazines; Renin | 1988 |
Increased intratumor concentration of fluorescein-isothiocyanate-labeled neocarzinostatin in rats under angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Antibiotics, Antineoplastic; Biological Transport; Fluorescein-5-isothiocyanate; Fluoresceins; Hypertension; Neoplasms, Experimental; Rats; Thiocyanates; Zinostatin | 1988 |
Transmural distribution of biochemical markers of total protein and collagen synthesis, myocardial contraction speed and capillary density in the rat left ventricle in angiotensin II-induced hypertension.
Topics: Alkaline Phosphatase; Angiotensin II; Animals; Biomarkers; Capillaries; Collagen; Heart Ventricles; Hydroxyproline; Hypertension; Male; Myocardial Contraction; Myosins; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1988 |
Cosecretion of peptides derived from gamma-human atrial natriuretic polypeptide in normal volunteers and patients with essential hypertension and adrenal disorders.
Topics: Addison Disease; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Angiotensin II; Atrial Natriuretic Factor; Blood Volume; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Immunoassay; Pheochromocytoma | 1988 |
A new Australian kindred with the syndrome of hypertension and hyperkalaemia has dysregulation of atrial natriuretic factor.
Topics: Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Australia; Fludrocortisone; Humans; Hyperkalemia; Hypertension; Pedigree; Renin; Syndrome | 1988 |
Atrial natriuretic peptide, angiotensin, norepinephrine and electrolyte in cerebrospinal fluid of essential hypertension.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Electrolytes; Humans; Hypertension; Middle Aged; Norepinephrine | 1988 |
Enhanced in vivo responsiveness of presynaptic angiotensin II receptor-mediated facilitation of vascular adrenergic neurotransmission in spontaneously hypertensive rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Aorta; Blood Pressure; Blood Vessels; Captopril; Electric Stimulation; Hypertension; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Cell Surface; Sympathetic Nervous System; Synaptic Transmission | 1985 |
Apparently high plasma angiotensin II levels in patients with essential hypertension treated by converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Dipeptides; Enalapril; Enzyme Inhibitors; Humans; Hypertension; Radioimmunoassay | 1985 |
Adrenocortical function in deoxycorticosterone acetate (DOCA)-hypertensive Yucatan miniature swine.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Desoxycorticosterone; Dose-Response Relationship, Drug; Hydrocortisone; Hypertension; Male; Swine; Swine, Miniature | 1985 |
The effect of dietary supplementation with linoleic and gammalinolenic acids on the pressor response to angiotensin II--a possible role in pregnancy-induced hypertension?
Topics: Adult; Angiotensin II; Blood Pressure; Diet; Female; gamma-Linolenic Acid; Heart Rate; Humans; Hypertension; Linoleic Acid; Linoleic Acids; Linolenic Acids; Pregnancy; Pregnancy Complications, Cardiovascular; Vitamins | 1985 |
Correction of abnormal renal blood flow response to angiotensin II by converting enzyme inhibition in essential hypertensives.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dipeptides; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Renal Circulation; Sodium | 1985 |
Regulation of platelet receptors for angiotensin II in man.
Topics: Adult; Angiotensin II; Blood Platelets; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Receptors, Angiotensin; Receptors, Cell Surface; Sodium | 1985 |
[Drugs that block the angiotensin converting enzyme].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dipeptides; Drug Administration Schedule; Enalapril; Humans; Hypertension; Kidney; Kidney Glomerulus | 1985 |
Are non-modulating patients with essential hypertension a distinct subgroup? Implications for therapy.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Kidney; Male; Middle Aged; Natriuresis; Oligopeptides; Renal Circulation; Sodium; Teprotide | 1985 |
Synthesis and pharmacology of the potent angiotensin-converting enzyme inhibitor N-[1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanyl-(S)-pyroglutamic acid.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Chemical Phenomena; Chemistry; Diet, Sodium-Restricted; Dipeptides; Enalapril; Heart Rate; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Male; Rats; Rats, Inbred SHR | 1985 |
Graded regional vasodilation with converting enzyme inhibitors in conscious spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hypertension; Indoles; Rats; Rats, Inbred SHR; Renal Circulation; Renin; Splanchnic Circulation; Vascular Resistance; Vasodilation | 1985 |
Dysfunction of central angiotensinergic aminopeptidase activity in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin III; Animals; Blood Pressure; Brain; Endopeptidases; Hypertension; Leucine; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1985 |
Function of the autonomic nervous system in young, untreated hypertensive patients.
Topics: Adult; Angiotensin II; Blood Pressure; Catecholamines; Exercise Test; Humans; Hypertension; Isoproterenol; Lactates; Male; Physical Exertion; Pressoreceptors; Receptors, Adrenergic, beta; Sympathetic Nervous System; Vasoconstriction | 1986 |
The responses of adrenocorticotrophic hormone and cortisol to insulin-induced hypoglycaemic stress in man are unimpaired during chronic converting enzyme inhibition.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Hydrocortisone; Hypertension; Hypoglycemia; Insulin; Male; Renin | 1985 |
Non-modulating essential hypertension: a subset particularly responsive to converting enzyme inhibitors.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Kidney; Natriuresis; Renal Circulation; Renin-Angiotensin System; Sodium Chloride | 1985 |
[Clinical significance of serum angiotensin I-converting enzyme in essential hypertension].
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Bradykinin; Circadian Rhythm; Creatinine; Female; Fludrocortisone; Furosemide; Humans; Hypertension; Indomethacin; Male; Middle Aged; Peptidyl-Dipeptidase A; Plasma Volume; Posture; Propranolol; Renin | 1985 |
Dopaminergic control of aldosterone secretion in hypertensive patients chronically treated with an angiotensin converting enzyme inhibitor.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Dopamine; Dopamine Antagonists; Enalapril; Female; Humans; Hypertension; Male; Metoclopramide; Middle Aged; Peptidyl-Dipeptidase A | 1986 |
[A study on the pathophysiologic changes in different types of patients with essential hypertension based on traditional Chinese medical classification].
Topics: Adult; Aged; Angiotensin II; Cyclic AMP; Cyclic GMP; Female; Humans; Hypertension; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Middle Aged; Renin | 1985 |
Sodium increases angiotensin II receptors in neuronal cultures from brains of normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Brain; Cells, Cultured; Hypertension; Kinetics; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Receptors, Cell Surface; Sodium; Species Specificity | 1986 |
Pressor responsiveness in steroid-induced hypertension in man.
Topics: Adrenocorticotropic Hormone; Adult; Angiotensin II; Blood Pressure; Humans; Hydrocortisone; Hypertension; Male; Middle Aged | 1986 |
Alpha 1-adrenergic receptor-mediated downregulation of angiotensin II receptors in neuronal cultures.
Topics: Angiotensin II; Animals; Brain Stem; Cells, Cultured; Dopamine; Hypertension; Hypothalamus; Kinetics; Neurons; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Receptors, Cell Surface | 1986 |
Factors affecting renal vein renin ratio in renal artery stenosis. Secretion of inactive renin.
Topics: Angiotensin II; Enalapril; Humans; Hypertension; Hypertension, Renovascular; Kidney; Renal Artery Obstruction; Renal Circulation; Renal Veins; Renin | 1986 |
Cyclic AMP, the hyperresponsiveness factor from hog kidney.
Topics: Angiotensin II; Animals; Blood Pressure; Chromatography, Gel; Cyclic AMP; Hypertension; Kidney; Male; Norepinephrine; Rats; Swine | 1986 |
Zona glomerulosa cell responses to atrial natriuretic factor in genetically hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Kidney Glomerulus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride | 1986 |
Enalaprilat: an intravenous substitute for oral enalapril therapy. Humoral and pharmacokinetic effects.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Enalapril; Enalaprilat; Humans; Hypertension; Injections, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; Renin | 1986 |
Antihypertensive action and inhibition of tissue converting enzyme (CE) by three prodrug CE inhibitors, enalapril, ramipril and perindopril in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Enalapril; Hypertension; Indoles; Male; Perindopril; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin-Angiotensin System | 1986 |
Interrelation between the renin-angiotensin system and kallikrein-kinin system in patients with essential hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Female; Humans; Hypertension; Kallikreins; Kinins; Male; Middle Aged; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1986 |
Characterization of the alpha-1 adrenergic receptors in the thoracic aorta of control and aldosterone hypertensive rats: correlation of radioligand binding with potassium efflux and contraction.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Thoracic; Dibenzylchlorethamine; Hypertension; Muscle Contraction; Phentolamine; Potassium; Prazosin; Rats; Receptors, Adrenergic, alpha; Yohimbine | 1987 |
Renal abnormalities in nonmodulating essential hypertension.
Topics: Adrenal Glands; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Kidney; Natriuresis; Renal Circulation; Renin-Angiotensin System; Sodium Chloride | 1987 |
Effects of enalapril maleate on blood pressure, renin-angiotensin-aldosterone system, and peripheral sympathetic activity in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Enalapril; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1987 |
Effects of atrial natriuretic factor on the vasoconstrictor actions of the renin-angiotensin system in conscious rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Inbred Strains; Renal Circulation; Renin-Angiotensin System; Rheology; Vascular Resistance; Vasoconstriction | 1987 |
Role of endogenous angiotensin II and prostaglandins in the antihypertensive mechanism of angiotensin converting enzyme inhibitor in hypertension.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diet, Sodium-Restricted; Female; Humans; Hypertension; Indomethacin; Male; Prostaglandins; Sodium; Thromboxane B2 | 1987 |
Angiotensin converting enzyme inhibition reduces ACTH release due to hypoglycaemia.
Topics: Adrenocorticotropic Hormone; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Captopril; Depression, Chemical; Enalapril; Humans; Hydrocortisone; Hypertension; Male; Middle Aged | 1987 |
Differences in glomerular binding and response to angiotensin II between normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Kidney Glomerulus; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin; Renin | 1988 |
[Effect of captopril on renin-aldosterone system in essential hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1988 |
Effect of angiotensin converting enzyme inhibition on platelet angiotensin II content.
Topics: Adult; Angiotensin II; Blood Platelets; Captopril; Female; Humans; Hypertension; Male; Middle Aged | 1988 |
Sodium and responses to infused noradrenaline and angiotensin II in subjects predisposed to hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Epinephrine; Heart Rate; Humans; Hypertension; Infusions, Parenteral; Male; Norepinephrine; Renin; Sodium; Sodium, Dietary | 1988 |
Cerebrospinal fluid angiotensin II in patients with essential hypertension.
Topics: Angiotensin II; Humans; Hypertension; Renin; Sodium, Dietary | 1988 |
[Relation of plasma renin activity and angiotensin II level and traditional Chinese medicine differentiation in essential hypertension].
Topics: Adult; Aged; Angiotensin II; Female; Humans; Hypertension; Male; Medicine, Chinese Traditional; Middle Aged; Renin | 1988 |
Relationship of angiotensin II, aldosterone, arginine vasopressin, adrenaline and noradrenaline in plasma, blood and extracellular volumes to blood pressure in chronic glomerulonephritis.
Topics: Adolescent; Adult; Angiotensin II; Arginine Vasopressin; Blood Pressure; Blood Volume; Chronic Disease; Creatinine; Epinephrine; Extracellular Space; Female; Glomerulonephritis; Hormones; Humans; Hypertension; Male; Middle Aged; Norepinephrine | 1986 |
[Classifying renin activity and angiotensin II levels in essential hypertension (clustering analysis)].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin; Statistics as Topic | 1986 |
[Renin classification based on epidemiologic and biochemical factors in essential hypertension].
Topics: Angiotensin II; Female; Humans; Hypertension; Male; Regression Analysis; Renin | 1986 |
Role of pressor prostanoids in rats with angiotensin II-salt-induced hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Arteries; Bridged Bicyclo Compounds, Heterocyclic; Dinoprost; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Imidazoles; Kidney Cortex; Male; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; Rats; Rats, Inbred Strains; Sodium Chloride; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1988 |
Mechanism of the antihypertensive effect of K depletion in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Potassium Deficiency; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 1988 |
Brain angiotensin in the developing spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Brain Chemistry; Hypertension; Rats; Rats, Inbred SHR | 1988 |
Cardiovascular baroreceptor control during angiotensin-induced acute hypertension in the dog.
Topics: Acute Disease; Angiotensin II; Animals; Carotid Sinus; Dogs; Hemodynamics; Hypertension; Isoflurane; Pressoreceptors; Regional Blood Flow; Vascular Resistance | 1988 |
Low-dose aspirin. I. Effect on angiotensin II pressor responses and blood prostaglandin concentrations in pregnant women sensitive to angiotensin II.
Topics: Angiotensin II; Aspirin; Blood Pressure; Drug Administration Schedule; Drug Resistance; Female; Humans; Hypertension; Osmolar Concentration; Parity; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins; Thromboxane B2 | 1988 |
[Is the renin-angiotensin system implicated in the hypertensive effect of a water-soluble tissue extract?].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cattle; Female; Hypertension; Male; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Spleen; Tissue Extracts | 1988 |
Increases in renal angiotensin II content and tubular angiotensin II receptors in prehypertensive spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Iodine Radioisotopes; Kidney Tubules; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Angiotensin; Renin-Angiotensin System | 1988 |
Effect of acute and chronic ethanol on the agonist responses of vascular smooth muscle.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Ethanol; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Inbred Strains | 1988 |
Vascular hypertrophy and hypertension: a role for growth factors?
Topics: Angiotensin II; Animals; Blood Vessels; Feedback; Growth Substances; Hypertension; Hypertrophy; Male; Rats; Rats, Inbred Strains | 1988 |
Calcium efflux in cultured vascular smooth muscle cells from genetically hypertensive rats: effect of angiotensin II and vasopressin.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Hypertension; Muscle, Smooth, Vascular; Rats; Rats, Mutant Strains; Saralasin; Vasopressins | 1988 |
Growth rate and phospholipase C activity in cardiac and aortic spontaneously hypertensive rat cells.
Topics: Angiotensin II; Animals; Cell Division; Hypertension; Inositol Phosphates; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Type C Phospholipases | 1988 |
Angiotensin II inhibits baroreflex control of muscle sympathetic nerve activity and the heart rate in patients with essential hypertension.
Topics: Angiotensin II; Blood Pressure; Heart Rate; Humans; Hypertension; Phenylephrine; Pressoreceptors; Reflex; Sympathetic Nervous System | 1988 |
Contributions of the sympathetic nervous system, vasopressin and baroreceptor function in brain angiotensin II excess-induced hypertension in the dog.
Topics: Angiotensin II; Animals; Dogs; Hypertension; Injections, Intraventricular; Pressoreceptors; Sympathetic Nervous System; Vagotomy; Vasopressins | 1988 |
[Kinetics of tissue sodium metabolism and the vascular reactivity to vasopressor agents in healthy persons with different degree of risk of developing arterial hypertension].
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hypertension; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prognosis; Risk Factors; Skin; Sodium Chloride | 1988 |
[The effect of salt load on the vascular response in rats and its mechanisms].
Topics: Angiotensin II; Animals; Blood Pressure; Calmodulin; Hypertension; Male; Rats; Rats, Inbred Strains; Sodium Chloride | 1988 |
[Clinical and experimental studies on the pathogenesis in pregnancy induced hypertension].
Topics: Angiotensin II; Animals; Female; Hemodynamics; Humans; Hypertension; Iliac Artery; Ischemia; Kidney; Maternal-Fetal Exchange; Placenta; Posture; Pregnancy; Pregnancy Complications, Cardiovascular; Rabbits; Reflex; Regional Blood Flow; Renal Circulation; Uterine Contraction; Uterus; Vasoconstriction | 1988 |
Enhancement of 5-fluorouracil delivery to sarcoma 180 tissue under angiotensin II-induced hypertension chemotherapy.
Topics: Angiotensin II; Animals; Fluorouracil; Hypertension; Male; Mice; Sarcoma 180 | 1988 |
Characterization of the functional antagonism and antihypertensive activity displayed by a monoclonal antibody to angiotensin II.
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Decerebrate State; Hypertension; Immunotherapy; Ligation; Male; Norepinephrine; Rats; Rats, Inbred Strains; Renal Artery; Renin | 1988 |
Zona glomerulosa function after life-long suppression in two siblings with the hypertensive virilizing form of congenital adrenal hyperplasia.
Topics: 18-Hydroxycorticosterone; Adolescent; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Aldosterone; Angiotensin II; Child; Cortodoxone; Cytochrome P-450 CYP11B2; Desoxycorticosterone; Female; Humans; Hypertension; Male; Potassium Chloride; Renin; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases | 1988 |
Diabetes mellitus and hypertension. State of the art lecture.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Humans; Hypertension; Hypertension, Renovascular; Kidney; Norepinephrine; Prazosin; Rats; Time Factors; Vasopressins | 1988 |
Long-term captopril treatment. Angiotensin II receptors and responses.
Topics: Angiotensin II; Animals; Captopril; Drinking Behavior; Female; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System; Time Factors | 1988 |
[Correlation of the total activity of blood plasma renin with levels of active and inactive renin, angiotensinogen and angiotensin II under different functional loads in patients with hypertension].
Topics: Adult; Angiotensin II; Angiotensinogen; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Propranolol; Prostaglandins E; Renin; Renin-Angiotensin System; Sodium Chloride; Time Factors | 1988 |
Influence of age, sodium status and ACE-inhibition on glomerular binding and responsiveness to angiotensin II in normotensive and spontaneously hypertensive rats.
Topics: Age Factors; Angiotensin II; Animals; Captopril; Female; Hypertension; Kidney Glomerulus; Rats; Rats, Inbred SHR; Sodium, Dietary | 1988 |
Angiotensin II-induced changes in cochlear blood flow and blood pressure in normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cochlea; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Regional Blood Flow; Ultrasonography | 1988 |
Effect of high calcium intake on pressor responsivity in hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Calcium, Dietary; Dose-Response Relationship, Drug; Electrolytes; Epinephrine; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Renin | 1987 |
Exaggerated pressor response to centrally administered renin in freely moving, spontaneously hypertensive rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Blood Pressure; Brain; Dose-Response Relationship, Drug; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 1987 |
Hypertension in patients on chronic hemodialysis: the role of the renin-angiotensin system.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Hematocrit; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renal Dialysis; Renin; Renin-Angiotensin System; Sodium Chloride; Time Factors | 1987 |
Comparative measurements of immunoreactive renin, plasma renin activity and angiotensin II in human plasma.
Topics: Angiotensin II; Antibodies, Monoclonal; Humans; Hypertension; Hypertension, Renovascular; Nephrectomy; Radioimmunoassay; Renin; Trypsin | 1987 |
Inhibition of hypertension and salt intake by oral taurine treatment in hypertensive rats.
Topics: Administration, Oral; Angiotensin II; Animals; Drinking; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Sodium, Dietary; Taurine | 1987 |
Renin suppression by saline is blunted in nonmodulating essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Renin; Sodium Chloride | 1987 |
Measurement of circulating kinins, their changes by inhibition of kininase II and their possible blood pressure lowering effect.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Hypertension; Kinins; Norepinephrine; Renin | 1987 |
[Preliminary study on plasma 6-keto-prostaglandin F1 alpha levels before and after induction by furosemide in hypertensive patients].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Angiotensin II; Furosemide; Humans; Hypertension; Male; Posture; Renin; Renin-Angiotensin System | 1987 |
Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Calcium Channel Blockers; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Potassium Chloride; Renin; Time Factors | 1987 |
Effects of felodipine and metoprolol on blood pressure, plasma renin, angiotensin II, aldosterone and catecholamines in hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Electrocardiography; Felodipine; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Renin; Time Factors | 1987 |
Characteristics of hormonal and neurogenic mechanisms of deoxycorticosterone-induced hypertension.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Desoxycorticosterone; Dogs; Hemodynamics; Hypertension; Male; Pressoreceptors; Reflex; Renin-Angiotensin System; Sympathetic Nervous System | 1988 |
Contribution of vasopressin in dexamethasone-induced hypertension in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Pressure; Dexamethasone; Heart Rate; Hypertension; Male; Norepinephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Vasopressin | 1988 |
Vascular structure enhances regional resistance responses in mild essential hypertension.
Topics: Adult; Angiotensin II; Blood Vessels; Humans; Hypertension; Male; Middle Aged; Models, Biological; Norepinephrine; Vascular Resistance | 1988 |
Blunted aldosterone responsiveness to angiotensin II in normotensive subjects with familial predisposition to essential hypertension.
Topics: Adrenal Cortex; Adult; Aldosterone; Angiotensin II; Humans; Hypertension; Male; Sodium, Dietary | 1988 |
Vasoconstriction is amplified by autoregulation during vasoconstrictor-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Homeostasis; Hypertension; Jejunum; Male; Mesenteric Arteries; Phenylephrine; Rats; Rats, Inbred Strains; Vascular Resistance; Vasoconstriction | 1988 |
Hypotensive effect of chronic intrarenal infusion of acetylcholine during angiotensin hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Diuresis; Dogs; Hypertension; Hypotension; Infusions, Intra-Arterial; Natriuresis; Renal Artery | 1988 |
Studies on the anti-vasoconstrictor activity of BRL 34915 in spontaneously hypertensive rats; a comparison with nifedipine.
Topics: Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Female; Hypertension; Infusions, Intravenous; Nifedipine; Norepinephrine; Phenylephrine; Pyrroles; Rats; Rats, Inbred SHR; Vasoconstriction; Vasopressins | 1988 |
Relationship between serum prolactin concentration, vascular angiotensin sensitivity and arterial blood pressure during third trimester pregnancy.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Middle Aged; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Prolactin | 1988 |
[Studies on abnormalities of adrenal steroidogenesis in essential hypertension, primary aldosteronism and renovascular hypertension: responses of plasma steroids to angiotensin III].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adult; Aldosterone; Angiotensin II; Angiotensin III; Circadian Rhythm; Corticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Infusions, Intravenous; Male; Middle Aged; Progesterone | 1988 |
The effects of intravenous angiotensin II upon blood pressure and sodium and urate excretion in human pregnancy.
Topics: Adult; Angiotensin II; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Renin-Angiotensin System; Sodium; Uric Acid | 1988 |
Increased angiotensin II receptors in brain nuclei of DOCA-salt hypertensive rats.
Topics: Angiotensin II; Animals; Autoradiography; Blood Pressure; Brain; Brain Stem; Desoxycorticosterone; Hypertension; Iodine Radioisotopes; Male; Olfactory Bulb; Organ Specificity; Paraventricular Hypothalamic Nucleus; Preoptic Area; Rats; Rats, Inbred WKY; Receptors, Angiotensin; Reference Values; Sodium, Dietary; Subfornical Organ; Suprachiasmatic Nucleus | 1988 |
Central attenuation of baroreflex by angiotensin II in normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Brain; Cardiovascular System; Electric Stimulation; Hypertension; Male; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Reference Values; Reflex; Sympathetic Nervous System; Vasopressins | 1988 |
Vasopressor responses and hyperthermia by intracerebroventricular injections of penicillin, a pyrogen, in rats: involvement of brain angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Consciousness; Desoxycorticosterone; Drinking; Fever; Hypertension; Indomethacin; Injections, Intraventricular; Penicillin G; Pyrogens; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sodium Chloride; Sympathetic Nervous System | 1988 |
In vivo and in vitro effects of cicletanine in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium; Diuretics; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Inbred SHR | 1988 |
[Hemodynamic reactions in response to the intracerebral administration of angiotensin II to alert normotensive and hypertensive rats].
Topics: Angiotensin II; Animals; Hemodynamics; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Inbred SHR; Reference Values | 1987 |
Decreased in vitro responses to vasoconstrictors during gestation in normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Female; Hypertension; In Vitro Techniques; Male; Norepinephrine; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Species Specificity; Splanchnic Circulation; Vasoconstrictor Agents | 1987 |
Role of endothelial cells in responses of spontaneously hypertensive rat mesenteric arteries to norepinephrine and angiotensins.
Topics: Angiotensin I; Angiotensin II; Animals; Endothelium, Vascular; Hypertension; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred SHR; Vasoconstriction; Vasodilation | 1987 |
Angiotensin II potentiates the vasoconstrictive effect of norepinephrine in normotensive and hypertensive man.
Topics: Adult; Angiotensin II; Drug Synergism; Humans; Hypertension; Male; Muscle, Smooth, Vascular; Norepinephrine; Vascular Resistance | 1987 |
A reduction of central peptidergic responses in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Brain; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Saline Solution, Hypertonic | 1986 |
Effects of high-calcium and/or high-sodium diet on basal and angiotensin II-stimulated blood pressure in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Calcium, Dietary; Female; Hypertension; Rats; Rats, Inbred SHR; Sodium Chloride | 1986 |
Angiotensin II receptors in adrenal gland, pituitary gland and brain of sino-aortic denervated rats.
Topics: Adrenal Glands; Angiotensin II; Animals; Hypertension; Male; Medulla Oblongata; Pituitary Gland; Rats; Receptors, Angiotensin | 1986 |
Increased number of angiotensin II receptors in the subfornical organ of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Hypertension; Male; Neurosecretory Systems; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Subfornical Organ | 1986 |
Altered angiotensin-prostanoid interactions in umbilical arteries in pregnancy-induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Dinoprost; Dinoprostone; Female; Humans; Hypertension; In Vitro Techniques; Perfusion; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins; Prostaglandins E; Prostaglandins F; Thromboxane B2; Umbilical Arteries | 1986 |
A comparison of the effects of angiotensin II and norepinephrine on intrarenal arteries in the rat.
Topics: Angiotensin II; Animals; Hypertension; Male; Microscopy, Electron; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Renal Artery | 1987 |
Levels of brain angiotensin in the spontaneously hypertensive rat and treatment with ramiprilat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Hypertension; Pyrroles; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spinal Cord | 1986 |
Heightened pressor effect and dipsogenicity to intracerebroventricularly applied angiotensin II and III in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin III; Animals; Blood Pressure; Cerebral Ventricles; Drinking; Hypertension; Injections, Intraventricular; Leucine; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Thirst | 1986 |
Multiple factors contribute to the pathogenesis of hypertension in Cushing's syndrome.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Captopril; Cushing Syndrome; Dinoprostone; Female; Humans; Hydrocortisone; Hypertension; Kallikreins; Male; Middle Aged; Norepinephrine; Prostaglandins E; Renin; Renin-Angiotensin System | 1986 |
New insights into the medical management of primary aldosteronism.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Female; Humans; Hyperaldosteronism; Hypertension; Mineralocorticoid Receptor Antagonists; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Sodium Chloride | 1986 |
Effect of low doses of angiotensin II perfusion on the hypotensive action of captopril in anaesthetized normotensive and spontaneously hypertensive rats.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Catecholamines; Heart Rate; Hypertension; Injections, Intravenous; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1986 |
Blood pressure control in normotensive members of hypertensive families.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Creatinine; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Hypertension; Male; Norepinephrine; Potassium; Renin; Sodium | 1986 |
Effect of exercise on plasma concentrations of arginine vasopressin, angiotensin II and aldosterone in hypertensive and normotensive renal transplant recipients.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Blood Pressure; Exercise Test; Female; Heart Rate; Humans; Hypertension; Kidney Transplantation; Male; Osmosis; Physical Exertion; Renin-Angiotensin System | 1986 |
Diurnal patterns of blood pressure, heart rate and vasoactive hormones in normal man.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Catecholamines; Circadian Rhythm; Female; Heart Rate; Hormones; Humans; Hypertension; Male; Middle Aged; Renin | 1986 |
Immediate blood pressure response to 1 Sar-8Ile-angiotensins II and its modification by sodium depletion.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Renin | 1986 |
Participation of the renin-angiotensin system in the captopril-induced worsening of anemia in chronic hemodialysis patients.
Topics: Acute Disease; Adult; Anemia; Angiotensin II; Blood Cell Count; Captopril; Erythropoiesis; Female; Hematocrit; Hemoglobins; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Renin-Angiotensin System | 1986 |
Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Nifedipine; Potassium; Renin; Sodium | 1986 |
Is single oral administration of captopril beneficial in screening for primary aldosteronism?
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Diagnosis, Differential; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hypertension; Radioimmunoassay; Renin; Sodium Chloride | 1986 |
Central renin-angiotensin system and the pathogenesis of DOCA-salt hypertension in rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Desoxycorticosterone; Diuresis; Drinking; Hematocrit; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Pressoreceptors; Rats; Rats, Inbred WKY; Reflex; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride; Vasopressins | 1986 |
The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Catecholamines; Felodipine; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Physical Exertion; Renin | 1986 |
Effect of exogenous angiotensin II infusion after one year of captopril therapy in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Renin; Time Factors | 1986 |
The renin-angiotensin system is not responsible for hypertension following coronary artery bypass grafting.
Topics: Adult; Aldosterone; Angiotensin II; Cardiopulmonary Bypass; Hemodynamics; Humans; Hypertension; Middle Aged; Myocardial Revascularization; Norepinephrine; Postoperative Period; Prospective Studies; Renin; Renin-Angiotensin System | 1987 |
Pre- and postsynaptic effects of angiotensins in the femoral artery of spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adrenergic Fibers; Angiotensin I; Angiotensin II; Animals; Captopril; Dinoprost; Endothelium; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prostaglandins F; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Yohimbine | 1987 |
The role of the renin-angiotensin system in normotensive and hypertensive rats with varying renin status.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Captopril; Hypertension; Hypertension, Renal; Kidney Cortex; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renal Artery; Renin; Renin-Angiotensin System; Urethane | 1987 |
Area postrema is critical for angiotensin-induced hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Hypertension; Male; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Protein kinase C agonists increase the expression of angiotensin II receptors in neuronal cultures.
Topics: Angiotensin II; Animals; Brain Stem; Cells, Cultured; Cycloheximide; Hypertension; Hypothalamus; Kinetics; Neurons; Phorbol Esters; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1987 |
Angiotensin-sensitive neurons in the rat paraventricular nucleus: relative potencies of angiotensin II and angiotensin III.
Topics: Angiotensin II; Angiotensin III; Animals; Female; Hypertension; Iontophoresis; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity | 1987 |
Circulating [Met]enkephalin and catecholamine responses to acute hypotension and hypertension in anaesthetized greyhounds.
Topics: Anesthesia; Angiotensin II; Animals; Catecholamines; Chromatography, Gel; Dogs; Enkephalin, Methionine; Epinephrine; Hypertension; Hypotension; Nitroprusside; Norepinephrine; Radioimmunoassay; Time Factors | 1987 |
[Determination of pregnancy plasma angiotensin II and aldosterone level in hypertensive states].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular | 1987 |
Ethanol-induced hypertension involves impairment of baroreceptors.
Topics: Angiotensin II; Animals; Autonomic Nervous System; Blood Pressure; Depression, Chemical; Dose-Response Relationship, Drug; Ethanol; Heart; Heart Rate; Hypertension; Male; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred Strains | 1987 |
Activation of the central vasopressin system: a potential factor in the etiology of hypertension.
Topics: Angiotensin II; Animals; Cardiovascular System; Central Nervous System; Cerebral Ventricles; Hypertension; Melanocyte-Stimulating Hormones; Natriuresis; Peptides; Rats; Saline Solution, Hypertonic; Vasopressins | 1987 |
Nonuniformity of CBF response to NE- or ANG II-induced hypertension in rabbits.
Topics: Anesthesia; Angiotensin II; Animals; Blood Pressure; Cerebrovascular Circulation; Hypertension; Male; Norepinephrine; Periaqueductal Gray; Rabbits; Regional Blood Flow | 1987 |
Potentiation of pressor response to angiotensin II at the preoptic area in spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Male; Preoptic Area; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1987 |
Chronic dietary administration of tryptophan prevents the development of deoxycorticosterone acetate salt induced hypertension in rats.
Topics: Angiotensin II; Animals; Brain; Desoxycorticosterone; Diuresis; Drug Administration Schedule; Female; Heart Rate; Hypertension; Isoproterenol; Rats; Rats, Inbred Strains; Serotonin; Skin Temperature; Thirst; Tryptophan | 1987 |
Effects of nicardipine on the systemic and renal hemodynamics in acutely elevated blood pressure induced by vasoactive agents in conscious rabbits.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Drug Evaluation, Preclinical; Female; Heart Rate; Hemodynamics; Hypertension; Kidney; Nicardipine; Norepinephrine; Rabbits; Renal Circulation | 1987 |
Central role for sodium in the pathogenesis of blood pressure changes independent of angiotensin, aldosterone and catecholamines in type 1 (insulin-dependent) diabetes mellitus.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Epinephrine; Female; Humans; Hypertension; Hypertension, Renal; Kidney Function Tests; Male; Middle Aged; Norepinephrine; Sodium; Sodium, Dietary; Water-Electrolyte Balance | 1987 |
Acute hypertension selectively potentiates constrictor responses of large coronary arteries to serotonin by altering endothelial function in vivo.
Topics: Acetylcholine; Angiotensin II; Animals; Coronary Vessels; Dogs; Endothelium, Vascular; Female; Hypertension; Kinetics; Male; Methoxamine; Microscopy, Electron; Microscopy, Electron, Scanning; Serotonin; Time Factors; Vasoconstriction | 1987 |
[The role of the action of angiotensin II on the sympathetic nervous system in blood pressure regulation: investigated with 1-sarcosine, 8-isoleucine angiotensin II in essential hypertension].
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Sympathetic Nervous System | 1987 |
Changes in vascular responsiveness to vasoactive agents in the hindlimb of DOCA-salt hypertensive rats.
Topics: Angiotensin II; Animals; Cardiovascular Agents; Desoxycorticosterone; Dose-Response Relationship, Drug; Hindlimb; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Regional Blood Flow; Serotonin; Vasoconstrictor Agents; Vasodilator Agents | 1987 |
Abnormal vasopressin and aldosterone response to furosemide in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Arginine Vasopressin; Electrolytes; Female; Furosemide; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Osmolar Concentration; Renin-Angiotensin System; Urination | 1986 |
Vasopressor activity in incubated plasma of normal and hypertensive pregnant women.
Topics: Angiotensin II; Animals; Arm; Blood Pressure; Female; Humans; Hypertension; Male; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Rats; Rats, Inbred Strains; Uterus; Veins | 1986 |
Median preoptic nucleus ablation does not affect angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Drinking; Heart Rate; Hypertension; Male; Natriuresis; Potassium; Preoptic Area; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Abnormal renal sodium handling in essential hypertension. Relation to failure of renal and adrenal modulation of responses to angiotensin II.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Kidney; Kinetics; Middle Aged; Renal Circulation; Sodium; Time Factors | 1986 |
The effect of prolonged infusion and withdrawal of angiotensin II in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance Withdrawal Syndrome | 1986 |
Effect of sodium balance and calcium channel-blocking drugs on plasma aldosterone responses to infusion of angiotensin II in normal subjects and patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Calcium; Calcium Channel Blockers; Diet, Sodium-Restricted; Diltiazem; Female; Humans; Hypertension; Infusions, Intravenous; Middle Aged; Nifedipine; Sodium | 1986 |
Circumventricular organs in acutely hypertonic rats. II. Area postrema and choroid plexus.
Topics: Angiotensin II; Animals; Cerebral Ventricles; Choroid Plexus; Hypertension; Rats | 1986 |
Increased basal and thrombin-induced free calcium in platelets of essential hypertensive patients.
Topics: Adult; Angiotensin II; Blood Platelets; Calcium; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Ouabain; Thrombin | 1987 |
Pressor response to NaCl solution administered intracerebroventricularly or intracisternally to conscious normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain Stem; Cerebral Ventricles; Cisterna Magna; Drinking Behavior; Hypertension; Injections, Intraventricular; Male; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Saline Solution, Hypertonic; Sodium Chloride | 1986 |
Angiotensin II inhibits the K+-evoked release of [3H]norepinephrine from hypothalamic synaptosomes of the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Brain Stem; Hypertension; Hypothalamus; Male; Norepinephrine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Synaptosomes | 1987 |
Elevated blood pressure and angiotensin II are associated with accelerated loss of renal function in diabetic nephropathy.
Topics: Angiotensin II; Blood Glucose; Blood Pressure; Diabetic Nephropathies; Follow-Up Studies; Humans; Hypertension; Kidney; Longitudinal Studies; Renin-Angiotensin System | 1986 |
Evaluation of a novel antihypertensive agent, LY127210, in anesthetized and conscious spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Hydralazine; Hypertension; Male; Rats; Rats, Inbred SHR; Vascular Resistance | 1985 |
Intraocular pressure and systemic blood pressure after administration of vasoactive substances in hypertensive and normal rats.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Bradykinin; Hypertension; Intraocular Pressure; Kallikreins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values | 1985 |
[Chronic effect of norepinephrine, vasopressin and angiotensin II on urinary prostaglandin E and kallikrein excretion in conscious rats].
Topics: Angiotensin II; Animals; Hypertension; Kallikreins; Male; Norepinephrine; Prostaglandins E; Rats; Rats, Inbred Strains; Vasopressins | 1985 |
Increased angiotensin II binding affinity in the nucleus tractus solitarius of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain Stem; Hypertension; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 1985 |
Pathogenesis and treatment of hypertension associated with diabetes.
Topics: Angiotensin II; Blood Pressure; Diabetic Angiopathies; Humans; Hypertension; Norepinephrine; Renin-Angiotensin System; Risk; Smoking; Sodium; Sympathetic Nervous System; Water-Electrolyte Balance | 1985 |
Dopamine reduces aldosterone and 18-hydroxycorticosterone response to angiotensin II in patients with essential low-renin hypertension and idiopathic hyperaldosteronism.
Topics: 18-Hydroxycorticosterone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Corticosterone; Depression, Chemical; Dopamine; Female; Humans; Hyperaldosteronism; Hypertension; Male; Metoclopramide; Middle Aged; Prolactin; Renin; Stimulation, Chemical | 1985 |
[Plasma renin activity, plasma aldosterone concentration in the differential diagnosis of curable forms of secondary hypertension].
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Angiotensin II; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Renin | 1985 |
Renin-angiotensin mechanisms in oral contraceptive hypertension in conscious rats.
Topics: Angiotensin II; Animals; Blood Pressure; Contraceptives, Oral; Female; Hypertension; Mestranol; Norethynodrel; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Saralasin | 1985 |
Renal prostaglandin E2 and the renin-angiotensin system in hypertensive disorders in man.
Topics: Adult; Angiotensin II; Dinoprostone; Female; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Prostaglandins E; Renin | 1985 |
Effect of sleep on blood pressure and its correlates.
Topics: Angiotensin II; Blood Pressure; Catecholamines; Heart Rate; Humans; Hypertension; Renal Circulation; Renin; Sleep | 1985 |
Participation of vascular prostacyclin for the pathogenesis of experimental glucocorticoid hypertension in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Dexamethasone; Epoprostenol; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Renin | 1985 |
Relationships between blood pressure, heart rate and plasma epinephrine, norepinephrine, angiotensin II concentrations, plasma renin activity during chronic guanfacine therapy in patients with essential arterial hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Epinephrine; Female; Guanfacine; Guanidines; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Phenylacetates; Renin | 1985 |
[Results of the surgical management of primary aldosteronism based on a retrospective analysis of preoperative diagnosis and morphology of the adrenal gland].
Topics: Adrenal Glands; Adrenalectomy; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Corticosterone; Female; Follow-Up Studies; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Renin; Retrospective Studies | 1985 |
Hormonal responses to change in posture in hypertensive man. Evaluation by measurements of prostaglandin E2, renin activity, angiotensin II, and norepinephrine in renal venous blood.
Topics: Adult; Angiotensin II; Dinoprostone; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Posture; Prostaglandins E; Renal Veins; Renin | 1985 |
[Changes in reactivity of the renin-angiotensin-aldosterone system in old age as a risk factor in the development of hypertension].
Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Homeostasis; Humans; Hypertension; Hypothalamo-Hypophyseal System; Middle Aged; Pituitary-Adrenal System; Renin; Renin-Angiotensin System; Risk; Sympathetic Nervous System | 1985 |
A new look at the hypertension problem: the role of the renin system for analysis and treatment.
Topics: Angiotensin II; Arginine Vasopressin; Blood Pressure; Calcium; Captopril; Cold Temperature; Enzyme Precursors; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Magnesium; Natriuretic Agents; Propranolol; Renin; Renin-Angiotensin System; Saralasin; Sodium; Teprotide | 1985 |
Blood pressure responsiveness during the development of hypertension in the conscious spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Hexamethonium Compounds; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1985 |
Angiotensin-induced hypertension in conscious dogs: biochemical parameters and baroreceptor reflex.
Topics: Aldosterone; Angiotensin II; Animals; Body Weight; Consciousness; Disease Models, Animal; Dogs; Female; Heart Rate; Hypertension; Isoproterenol; Male; Pressoreceptors; Reflex; Renin | 1985 |
[Studies on the pathophysiology of pregnancy induced hypertension--endocrinological analysis by the method of angiotensin II and NaCl loading].
Topics: Aldosterone; Angiotensin II; Bradykinin; Female; Humans; Hypertension; Kallikreins; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Sodium Chloride | 1985 |
Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine.
Topics: Aged; Aldosterone; Angiotensin II; Blood Volume; Calcium; Chlorthalidone; Drug Therapy, Combination; Edema; Epinephrine; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Norepinephrine; Renin; Sodium | 1985 |
[Renin-angiotensin and the kallikrein-kinin systems at early stages of arterial hypertension].
Topics: Adolescent; Adult; Angiotensin II; Catecholamines; Female; Humans; Hypertension; Kallikreins; Kinins; Male; Middle Aged; Renin; Time Factors | 1985 |
Significance of angiotensin sensitivity test for prediction of pregnancy-induced hypertension.
Topics: Adult; Angiotensin II; False Positive Reactions; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Prognosis; Risk | 1986 |
Angiotensin II attenuates baroreflexes at nucleus tractus solitarius of rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cranial Nerves; Facial Nerve; Glossopharyngeal Nerve; Heart Rate; Hypertension; Male; Microinjections; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vagus Nerve | 1986 |
Efficacy of verapamil in patients resistant to other antihypertensive therapy.
Topics: Adult; Angiotensin II; Blood Pressure; Electrocardiography; Female; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Pressoreceptors; Verapamil | 1986 |
Subfornical organ. Does it protect against angiotensin II-induced hypertension in the rat?
Topics: Angiotensin II; Animals; Hemodynamics; Hypertension; Male; Neurosecretory Systems; Potassium; Rats; Rats, Inbred Strains; Subfornical Organ | 1985 |
Angiotensin II in the brain and brainstem of the DOCA salt hypertensive rat.
Topics: Angiotensin II; Animals; Brain Chemistry; Brain Stem; Desoxycorticosterone; Hypertension; Male; Neurosecretory Systems; Rats; Rats, Inbred Strains; Sodium Chloride | 1985 |
Induced hypertension chemotherapy for solid tumors based on functional characteristics of tumor vessels.
Topics: Angiotensin II; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Humans; Hypertension; Neoplasms; Regional Blood Flow | 1985 |
The effects of hydrogenated coconut oil, safflower oil, and evening primrose oil on development of hypertension and sodium handling in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Coconut Oil; Dietary Fats; Drinking; Erythrocytes; Fatty Acids; Fatty Acids, Essential; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Hypertension; Linoleic Acids; Male; Norepinephrine; Oenothera biennis; Oils; Plant Oils; Potassium; Rats; Rats, Inbred SHR; Safflower Oil; Sodium | 1985 |
The importance of endogenous digoxin-like factors in rats with various forms of experimental hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Digoxin; Hypertension; Immune Sera; Male; Nephrectomy; Rats; Rats, Inbred SHR; Sodium Chloride; Time Factors | 1985 |
Vasopressin-induced calcium increases in smooth muscle cells from spontaneously hypertensive rats.
Topics: Aminoquinolines; Angiotensin II; Animals; Aorta; Arginine Vasopressin; Calcium; Cells, Cultured; Fluorescent Dyes; Hypertension; Kinetics; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spectrometry, Fluorescence | 1985 |
Sodium-dependent hypertension produced by chronic central angiotensin II infusion.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Water; Drinking; Heart Rate; Hypertension; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Sodium; Sodium Chloride | 1985 |
Long-term effects of superior cervical ganglionectomy on cortical blood flow of non-anesthetized rabbits in resting and hypertensive conditions.
Topics: Adrenergic Fibers; Anesthesia; Angiotensin II; Animals; Blood Flow Velocity; Cerebral Cortex; Electric Stimulation; Female; Ganglia, Sympathetic; Histocytochemistry; Hypertension; Male; Norepinephrine; Rabbits; Restraint, Physical; Sympathectomy; Sympathetic Nervous System; Time Factors | 1985 |
Role of angiotensin in lethal cerebral hypoperfusion during treatment of acute hypertension.
Topics: Acute Disease; Adult; Angiotensin II; Blood Pressure; Cerebral Angiography; Cerebral Arteries; Humans; Hypertension; Ischemic Attack, Transient; Male; Nitroprusside; Perfusion; Vasoconstriction | 1985 |
Effect of calcium supplementation on the vascular sensitivity to angiotensin II in pregnant women.
Topics: Adult; Angiotensin II; Blood Pressure; Blood Vessels; Calcium; Drug Evaluation; Female; Gestational Age; Humans; Hypertension; Pregnancy; Pregnancy Complications, Hematologic | 1985 |
Cardiovascular and endocrine effects of potassium in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Cardiovascular System; Endocrine Glands; Hemodynamics; Hypertension; Male; Plasma Volume; Potassium; Pressoreceptors; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sodium | 1985 |
Cerebroventricular infusion of angiotensin antagonist does not influence hypertensive response to blood-borne angiotensin II.
Topics: Angiotensin II; Animals; Drug Interactions; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Neurosecretory Systems; Rats; Rats, Inbred Strains; Sodium | 1985 |
Isolated perfused mesenteric arteries of hypertensive and normotensive rats; response to norepinephrine, lysine vasopressin and angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Hypertension; In Vitro Techniques; Lypressin; Male; Mesenteric Arteries; Norepinephrine; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1985 |
Norepinephrine-related mechanism in hypertension accompanying renal failure.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Blood Volume; Debrisoquin; Female; Heart Rate; Humans; Hypertension; Isoproterenol; Kidney Failure, Chronic; Male; Middle Aged; Norepinephrine; Renal Dialysis | 1985 |
[Choroidal circulation in experimental hypertension. I. Choroidal blood flow in acute hypertension induced with angiotensin II].
Topics: Angiotensin II; Animals; Blood Pressure; Choroid; Hypertension; Rabbits; Regional Blood Flow; Vascular Resistance | 1985 |
[Determination of renin activity in blood plasma].
Topics: Angiotensin II; Animals; Ascites; Humans; Hypertension; Hypertension, Renal; Liver Cirrhosis; Male; Methods; Rats; Renin | 1970 |
Correlation between infiltration of mononuclear cells and production of connective tissue in acute hypertensive vascular disease.
Topics: Angiotensin II; Animals; Carbon; Connective Tissue; Female; Hypertension; Immune Sera; Lymphocytes; Mesenteric Arteries; Monocytes; Phagocytosis; Rats; Staining and Labeling; Time Factors | 1971 |
Altered urinary kallikrein excretion in human hypertension.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Angiotensin II; Esterases; Female; Humans; Hyperaldosteronism; Hypertension; Kallikreins; Kinins; Male; Middle Aged; Pheochromocytoma; Renal Artery Obstruction; Renin | 1971 |
Angiotensin, myocardial infarction, and strokes.
Topics: Adult; Angiotensin II; Animals; Cerebrovascular Disorders; Female; Humans; Hypertension; Middle Aged; Myocardial Infarction; Rabbits; Renin | 1972 |
Renin-angiotensin system in normal and in hypertensive disease of pregnancy.
Topics: Adult; Angiotensin II; Endopeptidases; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Puerperal Disorders; Radioimmunoassay; Renin | 1972 |
[Blood plasma content of angiotensinogen in arterial hypertension, circulatory insufficiency, myocardial infarct and liver cirrhosis].
Topics: Adrenal Glands; Alpha-Globulins; Angiotensin II; Chronic Disease; Glomerulonephritis; Glucocorticoids; Heart Failure; Humans; Hypertension; Liver; Liver Cirrhosis; Myocardial Infarction; Renin | 1972 |
Reduction of pressor effects of angiotensin I in man by synthetic nonapeptide (B.P.P. 9a or SQ 20,881) which inhibits converting enzyme.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Dose-Response Relationship, Drug; Electrocardiography; Humans; Hypertension; In Vitro Techniques; Injections, Intravenous; Male; Oligopeptides; Peptides; Protease Inhibitors; Time Factors; Venoms | 1973 |
Plasma renin, renin substrate, angiotensin II, and aldosterone in hypertensive disease of pregnancy.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Estrogens; Female; Gestational Age; Humans; Hypertension; Parity; Placenta; Posture; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Renin; Sodium | 1973 |
Hypertension and cerebral blood-flow.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebrovascular Circulation; Constriction; Humans; Hypertension; Vasomotor System | 1973 |
Pathogenesis of hypertensive encephalopathy.
Topics: Acute Disease; Aged; Angiotensin II; Animals; Blood Pressure; Brain Diseases; Carbon; Carbon Dioxide; Cats; Cerebrovascular Circulation; Dogs; Humans; Hypertension; Male; Middle Aged; Muscle, Smooth; Oxygen Consumption; Papio; Partial Pressure; Radioisotopes; Xenon | 1973 |
Plasma-aldosterone during oral-contraceptive therapy.
Topics: Acetates; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Contraceptives, Oral; Ethinyl Estradiol; Feedback; Female; Humans; Hypertension; Mestranol; Norethindrone; Radioimmunoassay; Renin; Time Factors | 1973 |
The cellular pathology of experimental hypertension. 7. Structure and permeability of the mesenteric vasculature in angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Carbon Isotopes; Cell Nucleus; Colloids; Cytoplasm; Endothelium; Hypertension; Lanthanum; Male; Mesenteric Arteries; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Permeability; Rats; Staining and Labeling | 1973 |
Lack of association between plasma-renin and history of heart-attack or stroke in patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Black People; Cerebrovascular Disorders; Creatinine; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Potassium; Radioimmunoassay; Renin; Retrospective Studies; Sodium | 1973 |
Angiotensin-II blockade in man by sar1-ala8-angiotensin II for understanding and treatment of high blood-pressure.
Topics: Adolescent; Adult; Aged; Angiotensin II; Blood Pressure Determination; Drug Evaluation; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Pyelonephritis; Renin | 1973 |
Editorial: Sodium and the pressor role of angiotensin.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Renal Dialysis; Renin; Sodium; Water-Electrolyte Balance | 1973 |
Interrelationships between blood pressure, renin, renin substrate and blood volume in terminal renal failure.
Topics: Adolescent; Adult; Alpha-Globulins; Angiotensin II; Blood Pressure; Blood Volume; Body Weight; Diet Therapy; Female; Glomerulonephritis; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nephrectomy; Protein Precursors; Pyelonephritis; Renal Dialysis; Renin; Sodium; Ultrafiltration | 1973 |
Sodium and the renin-angiotensin system in essential hypertension and mineralocorticoid excess.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Desoxycorticosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Mineralocorticoids; Renin; Sodium; Spironolactone | 1974 |
Renin and hypertension in childhood.
Topics: Aldosterone; Alpha-Globulins; Angiotensin II; Child; Child, Preschool; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney Diseases; Kidney Neoplasms; Nephrectomy; Radioimmunoassay; Renal Artery Obstruction; Renin; Sodium | 1974 |
Disturbed relationship of plasma-renin to blood-pressure in hypertension.
Topics: Adult; Age Factors; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin; Sex Factors; Sodium | 1974 |
Effects of adrenalectomy and of hypophysectomy on the development of sound-withdrawal hypertension.
Topics: Adrenal Glands; Adrenalectomy; Angiotensin II; Animals; Body Weight; Corticosterone; Female; Heart; Hypertension; Hypophysectomy; Norepinephrine; Organ Size; Potassium; Prednisolone; Rats; Sodium; Sound; Thymus Gland; Tyramine | 1973 |
Lesions in the septal nuclei of the rat raise mean systemic arterial pressure and prevent the development of sound-withdrawal hypertension.
Topics: Adrenal Glands; Angiotensin II; Animals; Body Weight; Female; Hippocampus; Hypertension; Kidney; Noise; Norepinephrine; Organ Size; Pituitary Gland; Rats; Rats, Inbred Strains; Septal Nuclei; Septum Pellucidum; Thyroid Gland; Tyramine; Vasopressins | 1973 |
[Pharmacological basis of the symptomatic treatment of arterial hypertension. I. Hemodynamic effects, mechanisms of action and side effects of antihypertensive agents].
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Hemodynamics; Humans; Hydralazine; Hypertension; Long-Term Care; Medulla Oblongata; Methyldopa; Monoamine Oxidase Inhibitors; Propranolol; Receptors, Adrenergic; Renin; Reserpine; Synaptic Transmission; Vasomotor System | 1973 |
Plasma renin and angiotensin levels in human hypertension following treatment.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Catecholamines; Diet; Humans; Hypertension; Pulse; Radioimmunoassay; Renin; Sodium | 1973 |
Proceedings: Mode of action of beta-adrenergic receptor blocking drugs in hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Brain; Cardiac Output; Humans; Hypertension; Norepinephrine; Renin | 1974 |
Sympathectomy for hypertension.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Diuretics; Guanethidine; Humans; Hypertension; Natriuresis; Propranolol; Renin; Sulfonamides; Sympathectomy; Thiadiazines | 1974 |
Plasma renin activity after the use of a new beta-adrenergic blocking agent (I.C.I. 66,032).
Topics: Acetamides; Adrenergic beta-Antagonists; Adult; Angiotensin II; Blood Pressure; Cardiac Volume; Creatinine; Electrocardiography; Humans; Hypertension; Middle Aged; Phenyl Ethers; Potassium; Propanolamines; Radioimmunoassay; Renin; Sodium | 1974 |
Drug therapy of hypertension: what we have, what we need, what we expect.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Arteries; Blood Pressure; Cardiac Glycosides; Cardiology; Congresses as Topic; District of Columbia; Diuretics; Drug Prescriptions; Drug Therapy, Combination; Family Practice; Humans; Hypertension; Methods; Muscle, Smooth; Phytotherapy; Plants, Medicinal; Rauwolfia; Renin; Societies, Medical; Sympathetic Nervous System; United States; Vascular Resistance; Vasodilator Agents; Water-Electrolyte Balance | 1974 |
Future trends in antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Plasma Volume; Prognosis; Renin; Vasodilator Agents | 1974 |
Dose-dependent opposite effects of angiotensin on renal sodium excretion.
Topics: Angiotensin II; Animals; Creatine; Hypertension; Natriuresis; Rabbits; Rats; Urine | 1965 |
Angiotensin infusion test.
Topics: Angiotensin II; Blood Pressure; Diagnosis, Differential; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal | 1965 |
Measurement of angiotensin II in blood.
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Immune Sera; Iodine Radioisotopes; Nephritis; Rabbits; Radioimmunoassay; Vascular Diseases | 1967 |
Conservative treatment of gangrene using mineralocorticoid-induced moderate hypertension.
Topics: Adult; Aged; Angiotensin II; Arteriosclerosis; Desoxycorticosterone; Exercise Therapy; Female; Fludrocortisone; Gangrene; Humans; Hypertension; Leg Ulcer; Male; Middle Aged; Smoking; Sodium Chloride; Thromboangiitis Obliterans | 1968 |
Renin inhibitor in plasma of uraemic patients.
Topics: Adolescent; Adult; Angiotensin II; Female; Glomerulonephritis; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney Failure, Chronic; Male; Middle Aged; Pheochromocytoma; Plasma; Renin; Sodium Chloride; Uremia | 1968 |
Renin and angiotensin.
Topics: Addison Disease; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Kidney; Potassium; Renin; Sodium | 1968 |
Radioimmunoassay determination of plasma-renin activity.
Topics: Angiotensin II; Animals; Antibody Formation; Biological Assay; Dimercaprol; Edetic Acid; Humans; Hypertension; Hypertension, Renal; In Vitro Techniques; Kinetics; Plasma; Protease Inhibitors; Radioimmunoassay; Renin | 1969 |
Complex effects of antibodies to polypeptide hormones.
Topics: Angiotensin II; Animals; Antibodies; Antigen-Antibody Reactions; Biological Assay; Blood Pressure; Bradykinin; Female; gamma-Globulins; Hypertension; Ileum; In Vitro Techniques; Inflammation; Melanocyte-Stimulating Hormones; Melanocytes; Muscle, Smooth; Peptides; Protease Inhibitors; Rabbits; Radioimmunoassay; Rats; Uterus | 1970 |
Arteriolar permeability and destruction of elastic membrane in hypertension.
Topics: Angiotensin II; Animals; Blood Proteins; Carbon; Colloids; Elastic Tissue; Female; Fluoresceins; Hypertension; Hypertension, Renal; Intestine, Small; Membranes; Mesenteric Arteries; Microscopy, Fluorescence; Permeability; Rats; Staining and Labeling | 1969 |
Arterial hypertension elicited by subpressor amounts of angiotensin.
Topics: Angiotensin II; Animals; Blood Vessels; Dogs; Guanethidine; Heart Rate; Hypertension; Hypertension, Renal; Sympathetic Nervous System; Tyramine; Vascular Resistance | 1965 |
The effect of ultra lente insulin administration in rats.
Topics: Angiotensin II; Animals; Diuresis; Hypertension; Insulin, Long-Acting; Norepinephrine; Rats; Water-Electrolyte Balance | 1964 |
Recent advances in hypertension.
Topics: Adrenal Glands; Angiotensin II; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney; Prognosis; Renin | 1965 |
The vascular reactivity to vasoactive substances and the electrolyte contents in arterial walls.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Carbon Tetrachloride; Chemical Phenomena; Chemistry; Desoxycorticosterone; Hydrochlorothiazide; Hypertension; Norepinephrine; Nucleosides; Potassium; Rabbits; Rats; Sodium; Sodium Chloride; Vasomotor System | 1965 |
In vitro demonstration of vascular hyper-responsiveness in experimental hypertension.
Topics: Angiotensin II; Animals; Arteries; Hypertension; In Vitro Techniques; Norepinephrine; Perfusion; Rats; Solutions; Vasomotor System; Vasopressins | 1965 |
[Venous blood angiotensin of juvenile arterial hypertensions].
Topics: Adolescent; Adult; Angiotensin II; Blood; Female; Humans; Hypertension; Male | 1965 |
Serum aminopeptidases, "angiotensinase," and hypertension. II. Amino acid beta-napthylamide hydrolysis by normal and hypertensive serum.
Topics: Aminopeptidases; Angiotensin II; Aspartic Acid; Colorimetry; Endopeptidases; Enzymes; Female; Humans; Hyperaldosteronism; Hypertension; In Vitro Techniques; Male; Naphthalenes; Pregnancy | 1965 |
Effect of uremic human plasma on renin activity.
Topics: Adolescent; Adult; Angiotensin II; Animals; Blood Pressure; Blood Transfusion; Dogs; Endopeptidases; Enzymes; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Rats; Renin; Swine; Uremia | 1965 |
Renal pressor material in various hypertensive diseases.
Topics: Angiotensin II; Biological Assay; Humans; Hypertension; Hypertension, Renal; Renin | 1965 |
[The intradermal test with angiotensin II and pathogenesis of essential hypertension].
Topics: Angiotensin II; Humans; Hypertension; Skin Tests | 1965 |
Cardiovascular reactivity in rats with spontaneous inherited hypertension and constricted renal artery hypertension.
Topics: Angiotensin II; Animals; Hexamethonium Compounds; Hypertension; Hypertension, Renal; Male; Norepinephrine; Rats; Vasopressins | 1966 |
Deoxycorticosterone acetate hypertension in dogs.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Dogs; Glomerulonephritis; Hypertension; Potassium Chloride; Renin; Sodium Chloride | 1965 |
The effect of angiotensinìi on the "clearance" of radioiodine from the skin in hypertension.
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Iodine Isotopes; Male; Middle Aged; Skin | 1966 |
Peripheral arterial and renal venous angiotensin concentration.
Topics: Angiotensin II; Blood Chemical Analysis; Chromatography, Paper; Humans; Hypertension; Potassium; Renal Veins; Sodium | 1966 |
Estimation of plasma renin and renin-substrate in various diseases in man.
Topics: Adult; Aged; Angiotensin II; Blood; Enzyme Precursors; Female; Glomerulonephritis; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Middle Aged; Nephrotic Syndrome; Renin | 1965 |
[Exploration of arterial hypertension by the angiotensin test].
Topics: Angiotensin II; Humans; Hypertension | 1965 |
[Study of the inactivation of angiotensin II by plasma of normal subjects and of hypertensive subjects].
Topics: Angiotensin II; Animals; Blood; Endopeptidases; Humans; Hypertension; Rats | 1965 |
[Studies on the renin-angiotensin-aldosterone system, especially their roles in the humoral regulating system and the cause of hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Dogs; Hypertension; Rats; Renin | 1965 |
On the role of renin-angiotensin system with special relation to aldosterone for the etiology of hypertension.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood; Hyperaldosteronism; Hypertension; In Vitro Techniques; Rats; Renal Veins; Renin; Urine | 1966 |
Vascular reactivity in experimental hypertension.
Topics: Angiotensin II; Animals; Hypertension; Norepinephrine; Rats; Vasomotor System | 1966 |
On the humoral factors in arterial hypertension.
Topics: Aldosterone; Angiotensin II; Blood; Humans; Hypertension; Renin; Urine | 1966 |
Significance of angiotensinase on renin-angiotensin system.
Topics: Angiotensin II; Blood; Endopeptidases; Humans; Hypertension; Renin | 1966 |
Angiotensin and its response in different diseases.
Topics: Angiotensin II; Humans; Hypertension | 1966 |
[Renin-angiotensin system and hypertension].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1965 |
Factors controlling renin in man.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Angiotensin II; Blood; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hypertension; In Vitro Techniques; Renin; Sodium | 1965 |
Angiotensin II infusion in renal disease with hypertension.
Topics: Adolescent; Adult; Angiotensin II; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Potassium; Sodium; Water | 1966 |
[Renin activity in the plasma in normal, increased and diminished blood pressure].
Topics: Angiotensin II; Blood Pressure; Glomerulonephritis; Humans; Hypertension; Hypertension, Renal; Hypotension; Renin | 1966 |
[Behavior of urinary aldosterone and electrolytes during infusion of angiotensin II in normal, essential and renovascular hypertensive subjects].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; In Vitro Techniques; Male; Urine; Water-Electrolyte Balance | 1965 |
[Action of angiotensin on the plasma cortisol].
Topics: Adolescent; Adult; Angiotensin II; Blood; Female; Humans; Hydrocortisone; Hypertension; In Vitro Techniques; Male; Middle Aged | 1965 |
Angiotensin infusion test in hypertension.
Topics: Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal | 1966 |
Diagnostic and physiologic implications of the angiotensin infusion test.
Topics: Angiotensin II; Blood Pressure; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Renal Artery Obstruction; Vasopressins | 1966 |
Changes in the carotid pulse which occur with age and hypertension.
Topics: Adult; Aging; Amyl Nitrite; Angiotensin II; Arteriosclerosis; Blood Pressure; Carotid Arteries; Electrocardiography; Heart Rate; Hemodynamics; Humans; Hypertension; Isoproterenol; Methoxamine; Phonocardiography; Pulse; Trimethaphan | 1966 |
[Aldosteronism].
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Animals; Edema; Female; Humans; Hyperaldosteronism; Hypertension; In Vitro Techniques; Male; Middle Aged; Rats; Renin | 1965 |
Effects of sinoaortic denervation on renal and adrenal hypertension.
Topics: Adrenal Medulla; Angiotensin II; Animals; Carotid Sinus; Denervation; Desoxycorticosterone; Hypertension; Hypertension, Renal; Paraganglia, Nonchromaffin; Rats; Renin | 1966 |
The angiotensin infusion test.
Topics: Adult; Angiotensin II; Aortic Coarctation; Blood Pressure Determination; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Renal Artery Obstruction; Vascular Diseases | 1966 |
Angiotensin blood levels in hypertensive and non-hypertensive diseases.
Topics: Acute Kidney Injury; Angiotensin II; Glomerulonephritis; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Liver Cirrhosis; Pyelonephritis | 1966 |
Effect of angiotensin on the pressor response to tyramine in normotensive subjects and hypertensive patients.
Topics: Adult; Angiotensin II; Blood Pressure; Ephedrine; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Norepinephrine; Renin; Tyramine | 1966 |
Angiotensin infusion test in arterial hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Middle Aged | 1966 |
Centrally mediated cardiovascular effects of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Cardiovascular System; Cats; Cerebral Ventricles; Hypertension; Metaraminol; Nictitating Membrane; Norepinephrine; Reserpine; Tachycardia | 1966 |
Measurement of renin and substrate concentrations in human serum.
Topics: Adolescent; Adult; Angiotensin II; Animals; Antimetabolites; Ascites; Biological Assay; Endopeptidases; Female; Humans; Hydrogen-Ion Concentration; Hypertension; Hypertension, Malignant; Liver Cirrhosis; Male; Middle Aged; Pregnancy; Rats; Renin; Swine | 1966 |
Digital vascular response to angiotensin II in normotensive and hypertensive subjects. Evidence for a qualitatively abnormal response to angiotensin in essential hypertension.
Topics: Adult; Angiotensin II; Blood Flow Velocity; Blood Pressure; Blood Vessels; Humans; Hypertension; Hypertension, Renal; Hypotension; Middle Aged; Vascular Resistance | 1967 |
Differential renal function studies of the effects of angiotensin in normotensive and hypertensive patients.
Topics: Adult; Angiotensin II; Diuresis; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Natriuresis; Sodium | 1967 |
[Effects of the rapid infusion of angiotensin on separate renal clearances in renovascular and essential hypertension. I].
Topics: Adult; Angiotensin II; Diagnosis, Differential; Diuresis; Electrolytes; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Renal Artery Obstruction | 1966 |
[Effects of the prolonged infusion of angiotensin on renal function and on electrolyte excretion in essential, renovascular and endocrine hypertension. II].
Topics: Angiotensin II; Cushing Syndrome; Diagnosis, Differential; Diuresis; Electrolytes; Humans; Hypertension; Hypertension, Renal; Liver Function Tests | 1966 |
[Angiotensin intradermoreaction in patients with liver cirrhosis in the ascitic phase. Results and interpretation in relation to the pathogenesis of the altered hydrosaline metabolism in cirrhogenic liver diseases].
Topics: Aldosterone; Angiotensin II; Ascites; Diabetes Insipidus; Heart Failure; Humans; Hypertension; Jaundice; Liver Cirrhosis; Renin; Skin Tests; Sodium Chloride; Water | 1966 |
Renal renin in unilaterally nephrectomized hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Female; Hypertension; Juxtaglomerular Apparatus; Kidney; Kidney Glomerulus; Nephrectomy; Organ Size; Peritoneal Dialysis; Rats; Renin; Sodium | 1965 |
Effect of angiotensin on the renal transport of sodium in essential hypertension.
Topics: Angiotensin II; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Kidney Function Tests; Natriuresis; Vascular Resistance | 1967 |
[Inactivation of angiotensin by total blood and hemolyzed blood of normal and hypertensive subjects].
Topics: Angiotensin II; Blood; Blood Pressure; Humans; Hypertension; Vasomotor System | 1964 |
[The pressure response to angiotensin and to noradrenaline in normal pregnancy and in the gestosic syndrome].
Topics: Angiotensin II; Blood Pressure; Female; Humans; Hypersensitivity; Hypertension; Norepinephrine; Pre-Eclampsia; Pregnancy; Skin Tests | 1967 |
The angiotensin infusion test and peripheral venous renin activity.
Topics: Adult; Aged; Angiography; Angiotensin II; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Renal; Kidney Function Tests; Male; Middle Aged; Renin; Urography | 1967 |
Course of hypertension during prolonged treatment with heterologous renin.
Topics: Angiotensin II; Animals; Antibody Formation; Blood Pressure; Female; Hypertension; Nephrectomy; Rats; Renin | 1966 |
Renin activity of the kidney in the spontaneously hypertensive rat.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Femoral Artery; Femoral Vein; Hypertension; Kidney; Nephrectomy; Rats; Renal Artery; Renal Veins; Renin | 1966 |
Induction of hypertension in rats, with large and small doses of angiotensin.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Rats | 1966 |
Spasmolysis and vasodilation. Experience with nylidrin HCl.
Topics: Angiotensin II; Animals; Blood Pressure; Chlorobutanol; Hypertension; Male; Mice; Sodium Chloride; Vasodilator Agents | 1967 |
Cardiovascular reactivity of rats during the development of salt hypertension. I. the response to polypeptides.
Topics: Angiotensin II; Animals; Atropine; Blood Pressure; Ergotamine; Female; Heart; Hypernatremia; Hypertension; Injections, Intravenous; Male; Oxytocin; Peptides; Rats; Sodium Chloride; Vagotomy; Vasopressins | 1966 |
[The regulation of the glomerulus filtrate and arterial blood pressure by the sodium gradients on the macula densa cells. A hypothesis on the stimulation of the renin-angiotensin system. Also a contribution on the genesis of various types of hypertension]
Topics: Angiotensin II; Arteries; Blood Pressure; Humans; Hypertension; Kidney Glomerulus; Kidney Tubules; Renin; Sodium | 1967 |
[Changes in plasmatic renin levels and sensitivity to the pressor action of angiotensin in dogs with hypertension induced by defrenation or by renal artery stenosis].
Topics: Angiotensin II; Animals; Carotid Arteries; Denervation; Dogs; Hypertension; Renal Artery Obstruction; Renin; Vagotomy | 1967 |
Influence of high renin substrate levels on renin-angiotensin system in pregnancy.
Topics: Adolescent; Adult; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; In Vitro Techniques; Juxtaglomerular Apparatus; Middle Aged; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Renin | 1967 |
Sympathetic and humoral vasoconstrictor responses in deoxycorticosterone hypertension.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Electric Stimulation; Female; Hypertension; Norepinephrine; Rats; Vasomotor System | 1967 |
[Renin-angiotensin of spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Female; Hypertension; Male; Rats; Renin | 1966 |
[Evaluation of angiotension skin test and the angiotensin infusion test].
Topics: Adolescent; Adult; Angiotensin II; Animals; Female; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Rats; Skin Tests | 1966 |
Plasma renin activity in hypertension.
Topics: Adult; Aged; Angiotensin II; Animals; Black or African American; Blood Pressure; Female; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney Diseases; Male; Middle Aged; Rats; Renin; Tissue Extracts; White People | 1967 |
[An experimental study on atypical coarctation of the aorta with special reference to pressure mechanism in hypertension].
Topics: Angiotensin II; Animals; Aortic Coarctation; Blood Pressure; Dogs; Female; Hypertension; Kidney Function Tests | 1966 |
Reversible inactivation of angiotensin in hypertensive and normotensive subjects.
Topics: Angiotensin II; Humans; Hypertension; Sodium Isotopes | 1967 |
[The effect of angiotensin on the renal elimination of sodium and potassium in arterial hypertension].
Topics: Adult; Aged; Angiotensin II; Electrolytes; Female; Humans; Hypertension; Male; Middle Aged | 1967 |
[On the mechanism of accelerated Na excretion during i.v. administration of highly hypertonic NaCl solutions in patients with essential hypertension. II. Tubular factors. Presumed functional relationships].
Topics: Adult; Angiotensin II; Blood Pressure Determination; Blood Volume; Female; Humans; Hypertension; Hypertonic Solutions; Injections, Intravenous; Kidney Concentrating Ability; Kidney Tubules; Male; Middle Aged; Natriuresis; Sodium Chloride; Water-Electrolyte Balance | 1966 |
[Angiotensinase activity in a modified skin test using angiotensin].
Topics: Angiotensin II; Endopeptidases; Humans; Hypertension; Skin Tests | 1966 |
Increased pressor responsiveness to kidney extracts.
Topics: Angiotensin II; Animals; Dogs; Hypertension; Injections, Subcutaneous; Kidney; Nephrectomy; Rats; Renin; Species Specificity; Tissue Extracts; Vasopressins | 1967 |
[The value of the angiotensin infusion test in differential diagnosis].
Topics: Angiotensin II; Glomerulonephritis; Heart Failure; Humans; Hypertension; Liver Cirrhosis; Metaraminol | 1967 |
[Sensitivity to pressor agents and hypovolemia].
Topics: Angiotensin II; Animals; Blood Pressure; Blood Volume; Dogs; Epinephrine; Hypertension; Lactates; Norepinephrine; Shock, Hemorrhagic; Vascular Resistance | 1967 |
Renin-angiotensin-aldosterone system during chronic thiazide therapy of benign hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin | 1968 |
[Medification of the hypertensive effects of catecholamines and of Val-5-angiotensin II in the rat, by the use of several estrogens].
Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Estriol; Estrogens, Conjugated (USP); Estrone; Hypertension; Rats | 1967 |
[Various aspects of the action of angiotensin II in essential arterial hypertension].
Topics: Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Hypertension, Renal | 1967 |
[Relationship between plasma sodium, hypertension and plasma and erythrocyte sodium concentration].
Topics: Angiotensin II; Blood Pressure; Erythrocytes; Humans; Hypertension; Renin; Sodium; Veins | 1968 |
[On the practical value of angiotensin test according to Kaplan and Silah in the diagnosis of renovascular hypertension].
Topics: Adult; Aminohippuric Acids; Angiotensin II; Creatinine; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Renal; Inulin; Male; Middle Aged; Natriuresis; Renal Artery Obstruction; Sodium | 1968 |
[Angiotensin resistance test in arterial hypertension of renal origin. Limitations and indications].
Topics: Adolescent; Adult; Angiotensin II; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Renal; Kidney Diseases; Male; Middle Aged; Renal Artery Obstruction | 1967 |
[Clinical study of cardiac asthma].
Topics: Aged; Angiotensin II; Blood Pressure; Bradycardia; Cardiac Output; Cardiomegaly; Circadian Rhythm; Dyspnea, Paroxysmal; Epinephrine; Exercise Test; Female; Heart Failure; Heart Valve Diseases; Hemodynamics; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Norepinephrine; Posture; Pulmonary Circulation; Serum Albumin, Radio-Iodinated | 1967 |
[Human angiotensin].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1967 |
[Problems of activated peptides in pathogenetic analysis].
Topics: Angiotensin II; Animals; Humans; Hypertension; Peptides | 1967 |
[Measurement of renin and angiotensin in the blood and renal renin].
Topics: Angiotensin II; Humans; Hypertension; Kidney; Methods; Renin | 1967 |
[Measurement of renin and angiotensin in the blood and renal renin].
Topics: Angiotensin II; Humans; Hypertension; Kidney; Methods; Renin | 1967 |
[Significance of renin-angiotensin determination].
Topics: Angiotensin II; Animals; Dogs; Humans; Hypertension; Methods; Rabbits; Rats; Renin | 1967 |
[Measurement of renin and angiotensin in the blood and renal renin].
Topics: Angiotensin II; Animals; Humans; Hypertension; Kidney; Methods; Rats; Renin | 1967 |
[Measurement of renin and angiotensin in the blood].
Topics: Angiotensin II; Humans; Hypertension; Methods; Renin | 1967 |
[Advantages and disadvantages of various methods of determination and our experiences].
Topics: Angiotensin II; Humans; Hypertension; Methods; Renin | 1967 |
[Measurement of renin and angiotensin in the blood and renal renin].
Topics: Angiotensin II; Humans; Hypertension; Kidney; Methods; Renin | 1967 |
[Measurement of renin and angiotensin in the blood].
Topics: Angiotensin II; Humans; Hypertension; Methods; Renin | 1967 |
[Measurement of renin and angiotensin in the blood and in the kidney].
Topics: Angiotensin II; Humans; Hypertension; Kidney; Methods; Renin | 1967 |
[Problems of vascular reactivity in the development of hypertension].
Topics: Angiotensin II; Animals; Blood Vessels; Hypertension; In Vitro Techniques; Norepinephrine; Rats; Renin | 1967 |
The renin-angiotensin system and hypertension.
Topics: Angiotensin II; Blood Pressure; Humans; Hypertension; Renin; Water-Electrolyte Balance | 1968 |
[Value and limitation of the perfusion test with angiotensin].
Topics: Angiotensin II; Blood Pressure; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Perfusion; Prognosis | 1968 |
Pressor response to angiotensin II in hypertension. Correlation with plasma renin activity and response to norepinephrine and metaraminol.
Topics: Adolescent; Adult; Aged; Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Infusions, Parenteral; Metaraminol; Middle Aged; Norepinephrine; Renin | 1968 |
Blood angiotensinase activity in relation to the breakdown of angiotensin II amide and nonisotopic phenylthiocarbamyl-angiotensin II amide in hypertensive and normotensive patients.
Topics: Analysis of Variance; Angiotensin II; Endopeptidases; Female; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Sulfur Isotopes | 1968 |
[Changes in the hypertensive effects of angiotensin by adrenergic and anti-adrenergic agents].
Topics: Amphetamine; Angiotensin II; Animals; Blood Pressure; Bretylium Compounds; Cocaine; Desipramine; Dibenzylchlorethamine; Epinephrine; Female; Guanethidine; Hypertension; Isoproterenol; Male; Metaraminol; Norepinephrine; Normetanephrine; Phenethylamines; Phenoxybenzamine; Phentolamine; Rats; Reserpine; Sympatholytics | 1968 |
[Experimental hypertension].
Topics: Angiotensin II; Animals; Endocrine System Diseases; Hyperaldosteronism; Hypernatremia; Hypertension; Hypertension, Renal; Hyperthyroidism; Kidney Diseases; Renin | 1966 |
[Comparative studies on the blood pressure effect of alpha- and beta-Angiotensin II in intravenous infusions].
Topics: Adrenal Gland Diseases; Angiotensin II; Biliary Tract Diseases; Blood Pressure; Humans; Hypertension; Infusions, Parenteral; Kidney Diseases; Liver Diseases | 1966 |
[Dynamic study of the urinary excretion of electrolytes in arterial hypertension].
Topics: Adolescent; Adult; Angiotensin II; Chlorides; Desoxycorticosterone; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Sodium | 1967 |
Vascular responses in mesenteric arteries from genetic and renal hypertensive rats.
Topics: Angiotensin II; Animals; Ferrocyanides; Hypertension; Hypertension, Renal; Male; Mesenteric Arteries; Norepinephrine; Perfusion; Rats; Vascular Resistance; Vasomotor System | 1968 |
Renin and erythropoietin in normotensive and in hypertensive patients.
Topics: Adolescent; Adult; Aged; Anemia; Angiotensin II; Blood Pressure; Blood Volume; Creatinine; Erythropoietin; Female; Hematocrit; Humans; Hypertension; Hypertension, Renal; Injections, Intravenous; Iron Isotopes; Male; Middle Aged; Potassium; Proteinuria; Renin; Sodium | 1968 |
The effect of transient renal anoxia and portacaval transposition on canine arterial blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Dogs; Hypertension; Hypoxia; Kidney; Kidney Diseases; Organ Size; Portacaval Shunt, Surgical; Portal Vein; Radiography; Renal Artery | 1968 |
Interrelationship between angiotensin and catecholamines.
Topics: Adrenal Glands; Adult; Angiotensin II; Animals; Blood Pressure; Catecholamines; Dogs; Epinephrine; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Injections, Intraperitoneal; Male; Myocardium; Norepinephrine; Rats; Sympathetic Nervous System; Tyramine | 1968 |
[On the regulation of renin secretion through angiotensin].
Topics: Angiotensin II; Humans; Hypertension; Hypertension, Renal; Infusions, Parenteral; Norepinephrine; Renin; Veins | 1967 |
Angiotensinase activity using human crude angiotensin.
Topics: Angiotensin II; Centrifugation; Endopeptidases; Glomerulonephritis; Hepatitis; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney; Liver; Liver Cirrhosis; Renin | 1968 |
Angiotensin-infusion test. Correlation with renin activity in peripheral venous blood.
Topics: Adult; Angiotensin II; Chronic Disease; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Diseases; Male; Renin; Veins | 1968 |
[Experiences with the angiotensin infusion test according to Kaplan and Silah in the diagnosis of hypertension].
Topics: Angiotensin II; Humans; Hypertension | 1967 |
[Relations between sodium metabolism of the erythrocytes and vascular reactibility in normotensive subjects with a family history of hypertension].
Topics: Adult; Angiotensin II; Blood Vessels; Erythrocytes; Female; Humans; Hypertension; Male; Norepinephrine; Sodium; Vasoconstrictor Agents; Water-Electrolyte Balance | 1967 |
Plasma renin activity and angiotensin pressor dose in hypertension correlation and diagnostic implications.
Topics: Analysis of Variance; Angiotensin II; Blood Pressure; Diagnosis, Differential; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Renal Artery Obstruction; Renin; Water-Electrolyte Balance | 1968 |
Effect of corticotropin on aldosterone excretion and plasma renin in normal subjects, in essential hypertension and in primary aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Diet; Humans; Hyperaldosteronism; Hypertension; Natriuresis; Renin; Sodium; Water-Electrolyte Balance | 1968 |
Hypermineralocorticoidism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Angiotensin II; Cushing Syndrome; Female; Humans; Hyperaldosteronism; Hypertension; Hyperthyroidism; Male; Mineralocorticoids; Renin; Secretory Rate; Tritium | 1968 |
[The juxtaglomerular apparatus and renin secretion in experimental arterial hypertension].
Topics: Angiotensin II; Animals; Hypertension; Juxtaglomerular Apparatus; Microscopy, Electron; Pressure; Renin; Sodium; Stimulation, Chemical; Water-Electrolyte Balance | 1965 |
[Renin and aldosterone in human arterial hypertension (excluding Conn's syndrome)].
Topics: Adult; Aldosterone; Angiotensin II; Diagnosis, Differential; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Male; Nephrectomy; Renal Artery Obstruction; Renin; Sodium | 1965 |
[Estimation of serum levels of endogenous angiotensin by the infusion test of exogenous agniotensin].
Topics: Angiotensin II; Humans; Hypertension; Sodium Chloride | 1967 |
[Aldosteronuria in the hypertensive patient with Addison's disease].
Topics: Addison Disease; Adrenocorticotropic Hormone; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged | 1968 |
[Behavior of the kallikrein-bradykinin system in the course of blood pressure increases].
Topics: Adolescent; Adult; Angiotensin II; Bradykinin; Chronic Disease; Female; Humans; Hypertension; Infusions, Parenteral; Kallikreins; Male; Middle Aged | 1968 |
[Influence of experimental sodium chloride depletion on water-electrolyte metabolism, blood pressure and reaction ability of the vascula system in young hypertonics].
Topics: Adult; Age Factors; Aldosterone; Angiotensin II; Blood Vessels; Electrolytes; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Sodium; Sodium Chloride; Water-Electrolyte Balance | 1968 |
[On the diagnostic value of the angiotensin infusion test].
Topics: Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Infusions, Parenteral | 1967 |
[Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders].
Topics: Adult; Angiotensin II; Animals; Bile Duct Neoplasms; Biliary Tract Diseases; Blood Pressure; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloramphenicol; Endopeptidases; Erythromycin; Female; Gout; Hepatitis; Humans; Hypertension; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Liver Neoplasms; Male; Mercaptopurine; Middle Aged; Nephrotic Syndrome; Rats | 1968 |
[The surgical treatment of a patient with renovascular hypertension and the significance of the renin-angiotensin system in its development].
Topics: Adult; Angiotensin II; Blood Pressure Determination; Female; Humans; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Renin | 1966 |
Centrally mediated orthostatic hypotension. Report of cases.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Blood Pressure; Blood Volume; Bradycardia; Central Nervous System; Cold Temperature; Diabetes Complications; Diet; Female; Humans; Hypertension; Hypotension, Orthostatic; Male; Middle Aged; Norepinephrine; Sodium; Vasomotor System | 1968 |
Adrenergic mechanisms in hypertension.
Topics: Adrenal Glands; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Brain Chemistry; Catecholamines; Dogs; Hypertension; Hypertension, Renal; Muscle, Smooth; Myocardium; Potassium; Rats; Sodium; Tyramine; Water | 1968 |
The value of the angiotensin infusion test in the diagnosis of true renovascular hypertension.
Topics: Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Methods | 1968 |
[Studies on plasma angiotensinase. Hypertension and plasma angiotensinase].
Topics: Angiotensin II; Animals; Blood Pressure; Endopeptidases; Glomerulonephritis; Humans; Hypertension; Kidney Function Tests; Liver Diseases; Liver Function Tests; Rabbits; Renal Artery | 1967 |
[Relation between the blood-pressure effect of angiotensin II and the mean arterial pressure, serum sodium, serum potassium, serum angiotensinase and plasma renin in man].
Topics: Angiotensin II; Arteries; Blood Pressure; Cushing Syndrome; Electrolytes; Endopeptidases; Humans; Hypertension; Hypertension, Renal; Plasma; Potassium; Renin; Sodium | 1968 |
[The reinin- angiotensin-aldosterone system in essential and renovascular hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Kidney; Male; Methods; Middle Aged; Natriuresis; Renin | 1968 |
[On the vasopressor effect and inactivation of angiotensin in essential and renal as well as experimental hypertension].
Topics: Adult; Angiotensin II; Animals; Aorta; Blood Pressure; Endopeptidases; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Norepinephrine; Rats | 1968 |
[Functional phenomena and disease].
Topics: Angiotensin II; Asthma; Bradykinin; Cardiovascular System; Digestive System; Dysautonomia, Familial; Endocrine Glands; Enzymes; Hormones; Humans; Hypertension; Mental Disorders; Migraine Disorders; Neoplasms; Serotonin | 1967 |
[Actions of diazoxide on the cardiovascular system, on the metabolism of the myocardium and on sympathetic discharges].
Topics: Angiotensin II; Animals; Cardiovascular System; Diazoxide; Dogs; Hemodynamics; Hypertension; Hypertension, Renal; Myocardium; Nicotine; Norepinephrine; Piperazines; Respiration; Sympathetic Nervous System | 1968 |
[Critical study of the angiotensin perfusion test].
Topics: Adolescent; Adult; Aged; Angiotensin II; Blood Volume; Diagnosis, Differential; Diuretics; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Methods; Middle Aged; Renin | 1968 |
Aldosterone production after suppression of corticotropic secretory activity.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Depression, Chemical; Dexamethasone; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hypertension; Renin; Secretory Rate | 1968 |
Vascular reactivity studies in hypertension.
Topics: Adolescent; Adult; Angiotensin II; Blood Vessels; Female; Hand; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Infusions, Parenteral; Kidney; Male; Middle Aged; Nephrectomy; Norepinephrine; Regional Blood Flow; Renin; Vascular Resistance; Vasomotor System | 1968 |
Effect of angiotensin on urine flow and electrolyte excretion in normal and toxemic pregnancy.
Topics: Adolescent; Adult; Angiotensin II; Diuresis; Electrolytes; Female; Humans; Hypertension; Postpartum Period; Pre-Eclampsia; Pregnancy | 1967 |
[Role of noradrenaline and angiotension on cerebral circulation in juvenile essential hypertension].
Topics: Adolescent; Adult; Angiotensin II; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Epinephrine; Humans; Hydrogen-Ion Concentration; Hypertension; Norepinephrine; Oxygen; Vascular Resistance | 1968 |
[On the reactivity of skin arterioles in hypertension under the influence of histamine].
Topics: Adolescent; Adult; Angiotensin II; Arteries; Blood Pressure; Body Temperature; Child; Female; Histamine; Humans; Hypertension; Hypertension, Renal; Injections, Intradermal; Male; Methyldopa; Middle Aged; Phytotherapy; Plants, Medicinal; Rauwolfia; Skin; Skin Tests | 1968 |
Diminished baroreflex sensitivity in high blood pressure.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Brachial Artery; Heart Rate; Humans; Hypertension; Middle Aged; Phenylephrine; Pressoreceptors; Reflex | 1969 |
[Rate of propagation of the sphygmic wave in the course of artificially induced hypertensive states].
Topics: Adult; Angiotensin II; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Pulse | 1967 |
Derangement of regional cerebral blood flow and of its regulatory mechanisms in acute cerebrovascular lesions.
Topics: Acute Disease; Adult; Aged; Angiotensin II; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebral Angiography; Cerebral Arteries; Cerebral Hemorrhage; Cerebrovascular Disorders; Dilatation; Electroencephalography; Humans; Hypercapnia; Hyperemia; Hypertension; Ischemic Attack, Transient; Middle Aged; Partial Pressure; Vasomotor System; Veins | 1968 |
Suppressed plasma renin activity in hypertension.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Angiotensin II; Animals; Biological Assay; Diagnosis, Differential; Female; Furosemide; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Male; Middle Aged; Posture; Potassium; Rats; Renin; Saliva; Sodium; Water-Electrolyte Balance | 1969 |
Reflex regulation of arterial pressure during sleep in man. A quantitative method of assessing baroreflex sensitivity.
Topics: Adult; Angiotensin II; Arousal; Arteries; Blood Pressure; Dreams; Heart Rate; Humans; Hypertension; Methods; Middle Aged; Movement; Pressoreceptors; Reflex; Sleep; Vagus Nerve; Wakefulness | 1969 |
[Skin reaction of healthy pregnant women and women with late toxemia to angiotensin II].
Topics: Angiotensin II; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Prognosis; Skin Tests | 1968 |
Conversion of alpha-L-angiotensin amide to beta-L-angiotensin during enzymatic degradation.
Topics: Aminopeptidases; Angiotensin II; Buffers; Cystine; Electrophoresis; Hydrogen-Ion Concentration; Hypertension; Oxytocin | 1968 |
Mechanism of renal hypertension. Utilization of phentolamine (Regitine) test in essential, renal and angiotensin induced hypertension.
Topics: Angiotensin II; Blood Pressure Determination; Catecholamines; Humans; Hypertension; Hypertension, Renal; Phentolamine; Uremia | 1968 |
Blood angiotensin II levels of normal and hypertensive subjects.
Topics: Angiotensin II; Aortic Diseases; Arteries; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Nephrectomy; Radioimmunoassay; Veins | 1969 |
Pressor response to angiotensins I and II and renin in rats treated with carbon tetrachloride.
Topics: Angiotensin II; Animals; Blood Pressure; Carbon Tetrachloride Poisoning; Dipeptidases; Fatty Liver; Female; Hypertension; Liver; Rats; Renin | 1969 |
[The renin, angiotensin and aldosterone system in secondary hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Renin | 1968 |
Anaesthesia in patients with disturbances of cerebral and coronary circulation.
Topics: Anesthesia; Angiotensin II; Aortic Arch Syndromes; Cerebrovascular Disorders; Coronary Disease; Heart Aneurysm; Humans; Hypertension; Norepinephrine; Vena Cava, Superior | 1966 |
Studies of plasma renin activity in patients with hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Diagnosis, Differential; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney Diseases; Male; Middle Aged; Posture; Renin | 1968 |
[Does the recent knowledge on the renin-angiotensin system have clinical applications?].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Feedback; Humans; Hyperaldosteronism; Hypertension; Juxtaglomerular Apparatus; Kidney; Kidney Failure, Chronic; Kidney Glomerulus; Kidney Tubules; Renal Artery Obstruction; Renal Veins; Renin; Sodium | 1968 |
[Determination of renin activity and aldosteronuria in 24 hypertensives].
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Renin; Sodium | 1968 |
[Renin and angiotensin].
Topics: Aldosterone; Angiotensin II; Animals; Arteries; Dogs; Humans; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Rabbits; Rats; Renin; Stimulation, Chemical; Veins | 1968 |
Penetration of circulating fluorescent proteins into walls of arterioles and venules in rats with intermittent acute angiotensin-hypertension.
Topics: Angiotensin II; Animals; Arteries; Blood Proteins; Female; Fluorescent Dyes; Hypertension; Intestine, Small; Microscopy, Fluorescence; Permeability; Rats; Veins | 1968 |
[Diagnostic significance of the angiotensin infusion test].
Topics: Adolescent; Adult; Aged; Angiotensin II; Child; Diabetic Nephropathies; Female; Glomerulonephritis; Heart Diseases; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Infusions, Parenteral; Liver Cirrhosis; Male; Metaraminol; Middle Aged; Nephritis | 1968 |
Accumulation of 3H-noradrenaline in cardiac and smooth muscle of rats with experimental hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Female; Hypertension; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Myocardium; Norepinephrine; Rats; Sodium Chloride; Tritium; Uterus | 1968 |
Blood renin levels in various types of arterial hypertension. Preliminary communication.
Topics: Adolescent; Adult; Angiotensin II; Arteries; Female; Glomerulonephritis; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney Calculi; Male; Middle Aged; Pyelonephritis; Renal Artery Obstruction; Renin | 1969 |
Medical grand rounds from the University of Alabama Medical Center.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Renin; Spironolactone | 1969 |
Transitory primary aldosteronism-like condition.
Topics: Aged; Angiotensin II; Chlorides; Diuretics; Female; Heart Diseases; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypertonic Solutions; Potassium; Renin; Sodium; Sodium Chloride; Vomiting; Water-Electrolyte Balance | 1968 |
[Determination of plasma angiotensinase activity in patients with hypertensive disease and symptomatic renal hypertension].
Topics: Angiotensin II; Animals; Endopeptidases; Humans; Hypertension; Hypertension, Renal; Methods; Rats | 1967 |
[Dynamic tests of the function of the renin-angiotensin-aldosterone system].
Topics: Adrenal Insufficiency; Aldosterone; Angiotensin II; Diagnosis, Differential; Diazoxide; Diet, Sodium-Restricted; Humans; Hypertension; Injections, Intravenous; Juxtaglomerular Apparatus; Posture; Renin; Water-Electrolyte Balance | 1969 |
[Plasma renin activity in peripheral venous blood under various stimulation conditions].
Topics: Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Arteriosclerosis; Blood Pressure; Creatinine; Glomerulonephritis; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Nephritis; Pheochromocytoma; Plasma; Pyelonephritis; Radioisotope Dilution Technique; Renal Artery; Renin; Urography; Veins | 1969 |
The production of sustained hypertension in dogs by a single transient anoxic episode.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Dogs; Hypertension; Kidney; Models, Biological; Photomicrography; Renal Artery; Renal Artery Obstruction; Renin; Time Factors | 1969 |
[Tensional regulation of chronic renal insufficiency patients treated by hemodialysis. Roles in constrictive action of angiotensin and renin activity].
Topics: Angiotensin II; Arteries; Blood Pressure; Body Weight; Humans; Hypertension; Kidney Failure, Chronic; Nephrectomy; Perfusion; Renal Dialysis; Renin; Water-Electrolyte Balance | 1968 |
Quantitative analysis of the pathophysiology of hypertension.
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Pressure; Blood Vessels; Cardiac Output; Electrolytes; Feedback; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney; Reflex; Renin; Vascular Resistance | 1969 |
The role of vessel wall reactivity in experimental hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arteries; Elasticity; Female; Hypertension; Hypertension, Renal; Kidney; Kymography; Male; Nephrectomy; Rats; Renin; Sodium Chloride; Vasomotor System | 1968 |
[Plasma renin activity and pressure-raising angiotensin dosage].
Topics: Angiotensin II; Child; Child, Preschool; Female; Humans; Hyperaldosteronism; Hypertension; Injections, Intravenous; Male; Methods; Renin | 1968 |
[Determination of renin activity in normal and hypertensive patients].
Topics: Angiotensin II; Humans; Hypertension; Nephrotic Syndrome; Renin | 1969 |
Clinical application of a simple, specific bioassay technique for measuring renin activity.
Topics: Acetylcholine; Angiotensin II; Animals; Biological Assay; Bradykinin; Cats; Colon; Diet, Sodium-Restricted; Epinephrine; Histamine; Humans; Hydrogen-Ion Concentration; Hypertension; Methods; Muscle Contraction; Muscle, Smooth; Nephrectomy; Norepinephrine; Rats; Renin; Tryptamines | 1969 |
Hypertension with inappropriate aldosterone stimulation.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Chlorides; Creatinine; Desoxycorticosterone; Diet; Humans; Hypertension; Male; Middle Aged; Potassium; Renin; Secretory Rate; Sodium | 1969 |
[Angiotensin-infusion test in the diagnosis of renovascular hypertension].
Topics: Adolescent; Adult; Aged; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Kidney Function Tests; Male; Middle Aged; Pyelonephritis; Renal Artery | 1969 |
[Effect of sympathicus blockade and increased blood flow through the kidneys on the action of angiotensin on the kidney function in hypertensives].
Topics: Angiotensin II; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Kidney Function Tests; Methods; Natriuresis; Pyrrolidines; Sodium; Sympathetic Nervous System | 1969 |
[Study on the renin-angiotensin-aldosterone system. Effects of sodium restriction and postural changes on plasma renin activity and fluctuation in urinary aldosterone].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Chromatography, Thin Layer; Diet, Sodium-Restricted; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypertension, Renal; Posture; Renin | 1969 |
The renin-angiotensin system in curable hypertension.
Topics: Aldosterone; Angiotensin II; Chemical Phenomena; Chemistry; Feedback; Humans; Hypertension; Renin | 1969 |
The renin-angiotensin system and its relation with the electrolyte balance in experimental hypertension.
Topics: Angiotensin II; Animals; Hypertension; Natriuresis; Potassium; Rats; Renin; Sodium | 1969 |
[Renin and arterial hypertension].
Topics: Adolescent; Adult; Aged; Angiography; Angiotensin II; Animals; Female; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Ischemia; Male; Middle Aged; Muscular Diseases; Posture; Renal Artery Obstruction; Renin; Urography | 1969 |
Studies of the renin-angiotensin-aldosterone system in patients with hypertension and in normal subjects.
Topics: Aldosterone; Angiotensin II; Blood Urea Nitrogen; Body Weight; Creatinine; Diet; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Plasma Volume; Posture; Renal Artery Obstruction; Renin; Sodium | 1969 |
[Importance of the angiotensin perfusion for the diagnosis of renovascular diseases].
Topics: Adolescent; Adult; Aged; Angiotensin II; Diagnosis, Differential; Female; Glomerulonephritis; Heart Failure; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Methods; Middle Aged; Perfusion | 1968 |
[Intravenous infusion of angiotensin for the diagnosis of arterial hypertension (Kaplan-Silah test)].
Topics: Adolescent; Adult; Angiotensin II; Humans; Hypertension; Injections, Intravenous; Liver Cirrhosis; Middle Aged; Renal Artery Obstruction | 1969 |
Renin-angiotensin-aldosterone system in hypertension. The clinical usefulness of measuring components of thisystem.
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Renin | 1969 |
[Inhibition of natriuretic effect of angiotensin by spirolactones and salidiuretics in cirrhosis and arterial hypertension].
Topics: Angiotensin II; Chlorthalidone; Creatinine; Depression, Chemical; Diet, Sodium-Restricted; Glomerular Filtration Rate; Humans; Hypertension; Inulin; Kidney Tubules; Liver Cirrhosis; Natriuresis; Norepinephrine; Potassium; Spironolactone; Water | 1969 |
[Diagnostic usefulness of intravenous infusions of angiotensin solution (Kaplan's test) in patients with arterial hypertension].
Topics: Adolescent; Adult; Angiotensin II; Female; Glomerulonephritis; Humans; Hypertension; Hypertension, Renal; Injections, Intravenous; Male; Middle Aged; Pyelonephritis | 1969 |
[Arterial hypertension and inadequate stimulation of aldosterone secretion. A new syndrome].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Corticosterone; Diet, Sodium-Restricted; Humans; Hypertension; Potassium; Renin; Sodium | 1969 |
Cardiovascular responses to hypertension and hypotension in dogs with denervated hearts.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Cardiac Output; Dogs; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Hypertension; Hypotension; Vascular Resistance | 1969 |
Drug-induced changes in blood pressure as recorded by direct and indirect methods.
Topics: Angiotensin II; Animals; Atropine; Blood Pressure; Blood Pressure Determination; Dogs; Guanethidine; Heart Rate; Hexamethonium Compounds; Hypertension; Isoproterenol; Methods; Nitroglycerin; Norepinephrine | 1969 |
Treatment of acute ischemic pain in the leg by induced hypertension.
Topics: Acute Disease; Adult; Aged; Analgesics; Angiotensin II; Female; Humans; Hypertension; Injections, Intravenous; Intermittent Claudication; Ischemia; Leg; Male; Middle Aged; Thrombosis | 1969 |
[Activity of aminopeptidase towards angiotensin II-amide in the serum during normal health, pregnancy, hypertension and liver disease].
Topics: Adult; Aged; Angiotensin II; Cholestasis; Endopeptidases; Female; Hepatitis A; Humans; Hypertension; Leucyl Aminopeptidase; Liver Cirrhosis; Middle Aged; Pregnancy | 1969 |
[Hypertension and endocrinology].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Cushing Syndrome; Endocrine System Diseases; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Pheochromocytoma; Renin | 1969 |
Pathogenesis of hypertension in rabbits with coarctation of the abdominal aorta.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Coarctation; Blood Pressure; Hypertension; Male; Rabbits; Renal Artery; Renin | 1969 |
[Significance of determination of renin-angiotensin system in hypertension].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Male; Renin | 1969 |
[Intravenous infusion of angiotensin following surgical treatment of arterial hypertension].
Topics: Angiotensin II; Humans; Hypertension; Injections, Intravenous; Renin | 1969 |
The importance of the renin angiotensin system in hypertension due to coarctation of the aorta.
Topics: Adolescent; Adult; Angiotensin II; Aortic Coarctation; Female; Humans; Hypertension; Male; Plasma; Posture; Renal Veins; Renin | 1969 |
Suppressed plasma renin activity in essential hypertension. Roles of plasma volume, blood pressure, and sympathetic nervous system.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Catecholamines; Diet; Epinephrine; Extracellular Space; Female; Guanethidine; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Posture; Potassium; Renin; Sodium; Spironolactone; Sympathetic Nervous System | 1970 |
[The angiotensin skin test in childhood].
Topics: Age Factors; Angiotensin II; Blood Pressure; Child; Child, Preschool; Humans; Hypertension; Infant; Infant, Newborn; Skin Tests | 1968 |
[Intravenous angiotensin test in the differential diagnosis of arterial hypertension].
Topics: Adult; Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Injections, Intravenous; Liver Cirrhosis; Middle Aged; Pyelonephritis | 1969 |
[Value of the Kaplan-Silah angiotensin infusion test in the etiologic diagnosis of arterial hypertension].
Topics: Adolescent; Adult; Aged; Angiotensin II; Child; Diagnosis, Differential; Female; Humans; Hypertension; Male; Methods; Middle Aged | 1968 |
Genetic influence on the renin-angiotensin system. Evidence for a renin inhibitor in hypertension-prone rats.
Topics: Angiotensin II; Animals; Hypertension; Hypertension, Renal; Rats; Renin | 1970 |
Aldosteronism in hypertensive disease.
Topics: Adrenal Gland Diseases; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Potassium; Renin; Sodium | 1970 |
The conversion of [35S] PTC-angiotensin I to PTC-angiotensin II in plasma of normotensive and hypertensive subjects.
Topics: Adolescent; Adult; Analysis of Variance; Angiotensin II; Blood Pressure; Blood Urea Nitrogen; Chromatography; Creatinine; Female; Humans; Hypertension; Male; Middle Aged; Phenylthiourea; Plasma; Sulfur Isotopes | 1970 |
[The angiotensin test in the differential diagnosis of hypertension].
Topics: Angiotensin II; Diagnosis, Differential; Female; Humans; Hypertension; Male | 1970 |
[Unitary responses in hypothalamus anterior and median areas associated with variations in arterial pressure and volemia].
Topics: Acetylcholine; Angiotensin II; Animals; Blood Volume; Cats; Electrodes; Electrophysiology; Epinephrine; Hypertension; Hypotension; Hypothalamus; Osmotic Pressure | 1970 |
[A case of arterial hypertension imputable to an estroprogestational contraceptive. Implication of the renin-angiotensin-aldosterone system].
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hyperaldosteronism; Hypertension; Lynestrenol; Mestranol; Progesterone; Renin | 1969 |
[Diagnostic value of the Kaplan-Silah angiotensin infusion test in arterial hypertension of various etiology].
Topics: Adolescent; Adult; Aged; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged | 1970 |
[Results of the intradermal hypertension test and Hines-Brown cooling test in various types of arterial hypertension].
Topics: Adult; Aged; Angiotensin II; Arteriosclerosis; Female; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged | 1970 |
Differences of plasma angiotensin concentration in rats with normal blood pressure, experimental renal and neurogenicointeroceptive hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Homeostasis; Hypertension; Hypertension, Renal; Male; Rats | 1970 |
[8th International Symposium on the Progress in Internal Medicine, 10-22-1969. Arterial Hypertension. 3. Physiopathology].
Topics: Angiotensin II; Animals; Dogs; Humans; Hypertension; Kidney Glomerulus; Renin | 1969 |
Liver enzymes in hypertension.
Topics: Adult; Angiotensin II; Blood Pressure Determination; Blood Protein Disorders; Blood Proteins; Chromatography, Paper; Endopeptidases; Enzyme Repression; Female; Humans; Hypertension; Liver; Liver Cirrhosis; Male; Middle Aged | 1970 |
Aldosterone, angiotensin, and hypertension.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension | 1970 |
[Renin-angiotensin system in pathology].
Topics: Adrenal Gland Diseases; Angiotensin II; Chronic Disease; Edema; Female; Humans; Hypertension; Hyponatremia; Kidney Diseases; Male; Pregnancy; Renin | 1968 |
[Results of angiotensin infusion test in renovascular hypertension and other forms of hypertension].
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Chronic Disease; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Male; Middle Aged; Prognosis; Renal Artery Obstruction | 1969 |
Hypertension in young females receiving anovulatory steroids.
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Drug Hypersensitivity; Female; Humans; Hypertension; Renin; Water-Electrolyte Balance | 1970 |
Experimentally induced changes in plasma angiotensinogen and plasma renin. Studies on normal, nephrectomized, ureterligated, hypoxic, partially corticectomized or medullectomized and renal or spontaneously hypertensive rats.
Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Angiotensin II; Animals; Blood Pressure; Body Weight; Creatinine; Female; Hematocrit; Hypertension; Hypertension, Renal; Hypoxia; Kidney; Nephrectomy; Radioimmunoassay; Rats; Renin; Ureter | 1969 |
[Significance of the renin-angiotensin system in the hypertension of aortic coarctation].
Topics: Angiotensin II; Animals; Aortic Coarctation; Blood Pressure; Humans; Hypertension; Kidney; Plasma; Renin | 1969 |
[Influence of bilateral nephrectomy on the renin-angiotensin system in man].
Topics: Adolescent; Adult; Angiotensin II; Humans; Hypertension; Male; Nephrectomy; Nitrogen; Renin; Uremia | 1969 |
The effect of angiotensin on the excretion of free and conjugated 5-hydroxyindoleacetic acid in man.
Topics: Angiotensin II; Blood Pressure; Diuresis; Humans; Hydroxyindoleacetic Acid; Hyperaldosteronism; Hypertension; Hypertension, Renal; Injections, Intravenous; Serotonin | 1970 |
[Effects of angiotensin on platelet aggregation].
Topics: Adenine Nucleotides; Angiotensin II; Blood Platelet Disorders; Blood Platelets; Catecholamines; Humans; Hypertension; Thrombosis | 1969 |
[Treating severe arterial insufficiency in the legs by induced hypertension].
Topics: Angiotensin II; Arteries; Humans; Hypertension; Ischemia; Leg; Mineralocorticoids; Regional Blood Flow; Vascular Diseases | 1968 |
[A test for assessing the responsiveness of plasma renin activity].
Topics: Angiotensin II; Biological Assay; Diazoxide; Diet, Sodium-Restricted; Furosemide; Humans; Hypertension; Hypertension, Renal; Hypotension, Orthostatic; Renin; Stimulation, Chemical; Time Factors | 1970 |
Role of angiotensin in the salt-hypertension of rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Hypertension; Immune Sera; Kidney; Male; Organ Size; Rats; Renin; Sodium Chloride | 1970 |
[Effect of exogenous angiotensin II on blood pressure in experimental nephrogenic and neurogenic-interoreceptive hypertension of rats].
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Hypertension, Renal; Male; Nephrectomy; Rats; Time Factors | 1969 |
The pathophysiology and bio-assay of the renin-angiotensin system.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biological Assay; Child; Child, Preschool; Female; Humans; Hypertension; Hypotension; Male; Methods; Middle Aged; Radioimmunoassay; Renin | 1970 |
Type and course of the inflammatory cellular reaction in acute angiotensin-hypertensive vascular disease in rats.
Topics: Angiotensin II; Animals; Arteries; Biological Transport, Active; Carbon; Cortisone; Female; Fluorescence; Hypertension; Inflammation; Lymphocytes; Monocytes; Phagocytosis; Proteins; Rats | 1970 |
Cardiovascular alterations in toxemia.
Topics: Angiotensin II; Blood Circulation Time; Cardiac Output; Catheterization; Female; Humans; Hypertension; Iodine Isotopes; Placenta; Plasma Volume; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Radionuclide Imaging; Uterus; Veins | 1970 |
Plasma renin activity in patients with coarctation of the aorta. A comment of the pathogenesis prestenotic hypertension.
Topics: Adolescent; Adult; Angiotensin II; Aorta, Thoracic; Aortic Coarctation; Blood Pressure Determination; Female; Humans; Hypertension; Kidney; Male; Posture; Renal Veins; Renin | 1969 |
Adrenal cortex, aldosterone, and hypertension. Report of an international workshop.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Female; Humans; Hypertension; Methods; Posture; Pregnancy; Radioimmunoassay; Radioisotope Dilution Technique; Rats; Renin; Sheep; Steroids | 1969 |
Catecholamine-releasing agent recovered from plasma of subjects with arterial hypertension.
Topics: Adrenal Glands; Adrenalectomy; Angiotensin II; Animals; Catecholamines; Dogs; Humans; Hypertension; Hypertension, Renal; Phenoxybenzamine; Propranolol; Rats; Renin | 1970 |
Abnormally sustained aldosterone secretion during salt loading in patients with various forms of benign hypertension; relation to plasma renin activity.
Topics: Adolescent; Adrenocortical Hyperfunction; Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Humans; Hyperaldosteronism; Hypertension; Potassium; Renal Artery Obstruction; Renin; Sodium | 1970 |
[Influence of treatment in the cardiovascular reactivity of the hypertensive patient].
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Cold Temperature; Female; Humans; Hypertension; Male; Posture; Stress, Psychological; Valsalva Maneuver; Vascular Resistance | 1968 |
[The renin-angiotensin system].
Topics: Angiotensin II; Animals; Dogs; Humans; Hypertension; Juxtaglomerular Apparatus; Renin | 1967 |
[Diagnostic value of the angiotensin test].
Topics: Adult; Aged; Angiography; Angiotensin II; Female; Humans; Hypertension; Hypertension, Renal; Male; Methods; Middle Aged | 1968 |
[Activity of catechol-ortho-methyltransferase under the influence of angiotensin and during DOCA hypertension in rats].
Topics: Angiotensin II; Animals; Brain; Desoxycorticosterone; Hypertension; Kidney; Male; Monoamine Oxidase; Myocardium; Rats; Spleen; Transferases | 1970 |
[The role of variations of pressive action of exogenic angiotensin in hypotensive action of diuretics. Attempt to determine the role of sodium balance and of natremia of the potassium balance and kalemia and renin activity].
Topics: Adult; Angiotensin II; Diuretics; Female; Humans; Hypertension; Middle Aged; Potassium; Renin; Sodium | 1970 |
Spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Brain Chemistry; Catecholamines; Female; Hypertension; Male; Myocardium; Rats; Spleen | 1970 |
[Studies of glucose concentration in plasma after experimental changes in blood pressure homeostasis in rabbits. II. Effect of synthetic angiotensin II on the blood glucose concentration of neurogenic interoreceptive hypertonic experimental animals].
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Female; Hypertension; Male; Pressoreceptors; Rabbits | 1969 |
Lack of increased renin-angiotensin activity in rats with spontaneous hypertension.
Topics: Angiotensin II; Animals; Biological Assay; Hypertension; Juxtaglomerular Apparatus; Rats; Renal Veins; Renin; Vasoconstrictor Agents | 1970 |
Vascular reactivity and mechanical properties of normal and cadmium-hypertensive rabbits.
Topics: Angiotensin II; Animals; Aorta; Cadmium; Hypertension; Injections, Intraperitoneal; Muscle Contraction; Norepinephrine; Rabbits | 1970 |
Neurogenic hypertension, with special reference to the central neurogenic effects of angiotensin.
Topics: Anesthesia; Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Cats; Dogs; Heart Rate; Hypertension; Injections, Intravenous; Neurochemistry; Norepinephrine; Rabbits; Vascular Resistance; Vertebral Artery | 1970 |
Metabolism and blood levels of angiotensin II in normal subjects, renal disease, and essential hypertension.
Topics: Angiotensin II; Arteries; Blood Pressure; Chlorothiazide; Chromatography, Paper; Contraceptives, Oral; Female; Humans; Hypertension; Hypertension, Renal; Immunoassay; Iodine Isotopes; Kidney Diseases; Male; Posture; Renin; Sodium; Veins | 1970 |
Biological significance of renin angiotensin immunization.
Topics: Angiotensin II; Animals; Antibodies; Antibody Formation; Antigen-Antibody Reactions; Blood Pressure; Hypertension; Hypertension, Renal; Immunization; Nephrectomy; Rabbits; Radioimmunoassay; Rats; Renal Artery Obstruction; Renin; Sodium | 1970 |
The role of angiotensin. Indirect studies with antiangiotensin plasma.
Topics: Angiotensin II; Animals; Antibody Specificity; Antigen-Antibody Reactions; Blood Pressure; Desoxycorticosterone; Female; Furosemide; Hypertension; Hypotension; Immune Sera; Immunity, Maternally-Acquired; Injections, Intravenous; Male; Nephrectomy; Norepinephrine; Rabbits; Rats; Renin; Sodium; Tritium | 1970 |
A microperfusion study of some factors controlling sodium absorption and glomerular filtration in the nephron of the rat.
Topics: Absorption; Angiotensin II; Animals; Extracellular Space; Glomerular Filtration Rate; Hypertension; Kidney; Kidney Glomerulus; Kidney Tubules; Models, Theoretical; Rats; Renin; Sodium; Water-Electrolyte Balance | 1970 |
A possible mechanism for hypertension induced by oral contraceptives. Diminished feedback suppression of renin release.
Topics: Adult; Angiotensin II; Blood Pressure; Blood Pressure Determination; Contraceptives, Oral; Estrogens; Feedback; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Renin | 1970 |
Changes in level of bradykininogen and pressor activity in blood of rats with experimental hypertension.
Topics: Angiotensin II; Animals; Bradykinin; Hypertension; Rats | 1969 |
The hemodynamic importance of structural vascular changes in essential hypertension.
Topics: Angiotensin II; Animals; Arteriovenous Fistula; Blood Flow Velocity; Blood Pressure; Blood Vessels; Cats; Dilatation; Female; Hand; Hindlimb; Humans; Hypertension; Hypotension; Injections, Intra-Arterial; Male; Muscle, Smooth; Norepinephrine; Plethysmography; Saphenous Vein; Vascular Resistance; Vasomotor System | 1970 |
Effects of general anesthesia on autoregulation of cerebral blood flow in man.
Topics: Adult; Angiotensin II; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Cyclopropanes; Female; Homeostasis; Humans; Hypertension; Hypotension; Krypton; Male; Nitrous Oxide; Oxygen; Partial Pressure; Phenylephrine; Plants, Medicinal; Plants, Toxic; Radioisotopes; Veratrum | 1970 |
Vascular reactivity of rats altered by cadmium and a zinc chelate.
Topics: Administration, Oral; Angiotensin II; Animals; Arteries; Blood Pressure; Cadmium; Hypertension; Injections; Injections, Intraperitoneal; Male; Norepinephrine; Rats; Sodium; Zinc | 1970 |
The influence of potassium administration and of potassium deprivation on plasma renin in normal and hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin II; Biological Transport, Active; Blood Pressure; Diet Therapy; Female; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Male; Middle Aged; Natriuresis; Potassium; Potassium Deficiency; Renin; Sodium | 1970 |
Lysosomes and pyroninophilia in mononuclear cells in hypertensive arterioles. Studies on the blood, arterioles and regional lymph nodes in experimental angiotensin-hypertension in rats.
Topics: Acid Phosphatase; Angiotensin II; Animals; Blood Cell Count; Female; Fluoroscopy; Histocytochemistry; Hypertension; Lymph Nodes; Lymphocytes; Lysosomes; Mesenteric Arteries; Monocytes | 1970 |
The secondary and tertiary inflammatory cellular reaction in arterioles damaged by acute angiotensin-hypertension in rats.
Topics: Angiotensin II; Animals; Blood Cell Count; Cell Aggregation; Female; Hypersensitivity, Delayed; Hypertension; Inflammation; Leukocytes; Mesenteric Arteries; Norepinephrine; Rats; Time Factors | 1970 |
Induced hypertension in the treatment of the ischaemic foot.
Topics: Aged; Angiotensin II; Arteriosclerosis; Blood Pressure; Foot; Foot Diseases; Humans; Hypertension; Injections, Intravenous; Ischemia; Middle Aged; Plethysmography; Regional Blood Flow; Sympathectomy | 1970 |
Intravenous infusion of angiotensin after surgical treatment of arterial hypertension.
Topics: Angiotensin II; Blood Pressure; Endarterectomy; Humans; Hypertension; Hypertension, Renal; Injections, Intravenous; Juxtaglomerular Apparatus; Kidney; Kidney Diseases; Nephrectomy; Posture; Renal Artery Obstruction; Renin; Stress, Physiological | 1970 |
Hypertension and the lupus syndrome.
Topics: Adenocarcinoma; Angiotensin II; Autopsy; Blood Pressure; Bone Marrow; Glomerulonephritis; Humans; Hypertension; Kidney; Lupus Erythematosus, Systemic; Male; Middle Aged; Neoplasm Metastasis; Nephrosclerosis; Prostaglandins; Prostatic Neoplasms; Renin | 1970 |
[Hypertensive activity in protein extracts of swine placenta].
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Placental Extracts; Proteins; Rats; Swine | 1969 |
[Results of angiotensin determination in renal hypertension].
Topics: Angiotensin II; Animals; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Prognosis; Rats | 1968 |
[Endocrine hypertension].
Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Aldosterone; Angiotensin II; Cushing Syndrome; Diagnosis, Differential; Electrocardiography; Epinephrine; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Norepinephrine; Pheochromocytoma; Prognosis; Renin | 1970 |
[Pathogenesis of essential hypertension].
Topics: Angiotensin II; Arthritis; Catecholamines; Humans; Hyperaldosteronism; Hypertension; Renin; Stress, Psychological; Water-Electrolyte Balance | 1970 |
[Importance of renin-angiotensin-aldosterone system in diverse forms of hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Animals; Contraceptives, Oral; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Pheochromocytoma; Renal Artery Obstruction; Renin | 1970 |
The pill, hypertension, and the toxemias of pregnancy.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Edema; Estrogens; Female; Humans; Hypernatremia; Hypertension; Natriuresis; Pre-Eclampsia; Pregnancy; Progesterone; Renin; Water-Electrolyte Balance | 1971 |
Hypertension, oral contraceptive agents, and conjugated estrogens.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Pressure Determination; Contraceptives, Oral; Estrogens, Conjugated (USP); Female; Humans; Hypertension; Kidney; Middle Aged; Natriuresis; Posture; Pregnancy; Renin; Secretory Rate; Sodium; Time Factors | 1971 |
Oral contraceptives and hypertensive disease: a cybernetic overview.
Topics: Angiotensin II; Contraceptives, Oral; Estrogens; Female; Homeostasis; Humans; Hypertension; Kidney; Renin | 1970 |
[The effect of extra- and intracellular electrolyte metabolism on vascular reactivity to norepinephrine and angiotensin in patients with hyperthyreosis and in normotensives with familial history of hypertension].
Topics: Adrenocortical Hyperfunction; Angiotensin II; Blood Circulation; Blood Pressure; Erythrocytes; Humans; Hypertension; Hyperthyroidism; Norepinephrine; Potassium; Sodium; Sodium Isotopes | 1970 |
The etiopathology of hypertension.
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Cardiac Output; Corticotropin-Releasing Hormone; Desoxycorticosterone; Heart; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypertension, Renal; Medulla Oblongata; Pressoreceptors; Renal Veins; Renin; Vascular Resistance | 1970 |
Problems in contraception.
Topics: Angiotensin II; Birth Rate; Blood Proteins; Contraception; Contraceptives, Oral; Estrogens; Family Planning Services; Female; Humans; Hypertension; Male; Methods; Pregnancy; Renin; Thromboembolism; United States | 1971 |
Evidence for an immunological factor in the hypertensive vascular disease.
Topics: Angiotensin II; Animals; Female; Hypersensitivity, Delayed; Hypertension; Inflammation; Lymphocytes; Mesenteric Arteries; Rats | 1971 |
A quantitative approach to the study of circulatory abnormality, especially of hypertension.
Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Body Fluids; Humans; Hypertension; Kidney; Pressoreceptors; Renin; Sodium; Water; Water-Electrolyte Balance | 1971 |
[Saluretic action of angiotensin II in essential and renovascular hypertension].
Topics: Adult; Angiotensin II; Diuresis; Electrolytes; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged | 1970 |
Chronic hypertension elicited by infusion of angiotensin into vertebral arteries of unanaesthetized dogs.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Catheterization; Central Nervous System; Chronic Disease; Dogs; Hypertension; Injections, Intra-Arterial; Injections, Intravenous; Jugular Veins; Sleep; Tachyphylaxis; Vertebral Artery; Wakefulness | 1971 |
[The influence of intra- and extracellular electrolyte metabolism on blood vessel reactability].
Topics: Angiotensin II; Biological Transport; Blood Vessels; Cell Membrane Permeability; Erythrocytes; Humans; Hypertension; Metabolism, Inborn Errors; Norepinephrine; Potassium; Sodium; Vascular Resistance | 1970 |
[Plasma renin activity and pregnancy].
Topics: Adult; Angiotensin II; Female; Humans; Hypertension; Methods; Pre-Eclampsia; Pregnancy; Renin | 1971 |
[Clarification of a hypertension].
Topics: Aldosterone; Angiotensin II; Aortic Coarctation; Blood Pressure Determination; Creatinine; Cushing Syndrome; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Function Tests; Pheochromocytoma; Renin; Uric Acid; Water-Electrolyte Balance | 1970 |
Evaluation of antihypertensive drugs in dogs with angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Dogs; Female; Hexamethonium Compounds; Hydralazine; Hypertension; Male; Nitrites; Sodium | 1971 |
The influence of angiotensin infusion on the urine composition in individual kidney function tests.
Topics: Adult; Angiotensin II; Creatinine; False Positive Reactions; Female; Humans; Hypertension; Kidney Function Tests; Male; Pyelonephritis; Renal Artery Obstruction; Sodium | 1971 |
Modified characteristics of the aortic baroreceptor activities in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Hypertension; Injections, Intravenous; Norepinephrine; Pressoreceptors; Rats | 1970 |
[Oral contraceptives and hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Progesterone; Renin; Sodium | 1971 |
[Correlations between plasma renin activity and blood pressure, erythrocyte count, hemoglobin, hematocrit as well as sodium, potassium, urea and creatinine in serum of hypertensive patients].
Topics: Adolescent; Adult; Aged; Angiotensin II; Aortic Coarctation; Blood Pressure; Creatinine; Erythrocyte Count; Erythropoietin; Female; Hematocrit; Hemoglobins; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Male; Middle Aged; Polycythemia; Potassium; Renin; Sodium; Urea; Water-Electrolyte Balance | 1971 |
[On hemodynamic control of renal function].
Topics: Angiotensin II; Diuresis; Heart Diseases; Hemodynamics; Hepatitis; Humans; Hypertension; Kidney; Kidney Function Tests | 1970 |
A study on hypertension. Effect of electrolytes on the catecholamine secretion from the adrenal gland by synthetic angiotensin. II.
Topics: Adrenal Glands; Angiotensin II; Animals; Calcium; Catecholamines; Dogs; Electrolytes; Epinephrine; Female; Hypertension; Injections, Intra-Arterial; Magnesium; Norepinephrine; Perfusion; Potassium; Renal Artery; Renal Veins; Stimulation, Chemical | 1970 |
Measurement of plasma angiotensin II by radioimmunoassay.
Topics: Addison Disease; Adrenal Gland Neoplasms; Adult; Angiotensin II; Animals; Cushing Syndrome; Female; Glomerulonephritis; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Immune Sera; Iodine Isotopes; Male; Middle Aged; Pheochromocytoma; Rabbits; Radioimmunoassay | 1971 |
A study of hypertension. The actions of synthetic angiotensin II on adrenal and myocardial catecholamines.
Topics: Adrenal Medulla; Angiotensin II; Animals; Catecholamines; Depression, Chemical; Epinephrine; Hypertension; Injections, Intravenous; Myocardium; Norepinephrine; Rats; Reserpine; Stimulation, Chemical | 1970 |
Modification of the cardiovascular effects of L-dopa in anesthetized dogs by inhibitors of enzymes involved in catecholamine metabolism.
Topics: Angiotensin II; Animals; Blood Pressure; Bradycardia; Carboxy-Lyases; Cresols; Dihydroxyphenylalanine; Dogs; Dopamine; Female; Heart Rate; Hydrazines; Hypertension; Hypotension; Male; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Tachycardia; Thiocarbamates | 1971 |
Significance of the renin-angiotensin system on the development of hypertension and the maintenance of elevated blood pressure levels.
Topics: Angiotensin II; Animals; Blood Pressure; Endopeptidases; Hypertension; Nephrectomy; Rats; Renin | 1971 |
On the role of aldosterone to hypertension, especially an extent of its participation.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Animals; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Kidney; Middle Aged; Potassium; Rats; Renin | 1971 |
The role of aldosterone in pathogenesis of arterial hypertension.
Topics: Addison Disease; Aldosterone; Angiotensin II; Animals; Arteries; Cushing Syndrome; Fundus Oculi; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Pheochromocytoma; Rats | 1971 |
Discussion on pathogenesis of hypertension.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Potassium; Renin; Sodium | 1971 |
A kinetic method for determination of plasma renin activity using radioassay of Angiotensin I.
Topics: Angiotensin II; Antigen-Antibody Complex; Antigen-Antibody Reactions; Antigens; Blood Pressure; Buffers; Diagnosis, Differential; Humans; Hydrogen-Ion Concentration; Hypertension; Hypertension, Renal; Immune Sera; Indicators and Reagents; Iodine Isotopes; Kidney; Kinetics; Methods; Radioimmunoassay; Renin; Serum Albumin, Bovine | 1971 |
Responses of mean arterial pressure to pressor agents and diuretics in renal hypertensive and salt hypertensive rats.
Topics: Anesthesia, General; Angiotensin II; Animals; Arteries; Autonomic Nerve Block; Blood Pressure; Desoxycorticosterone; Diuretics; Furosemide; Hydrochlorothiazide; Hypertension; Hypertension, Renal; Male; Norepinephrine; Pentobarbital; Rats; Renin; Sodium Chloride; Tyramine; Vasoconstrictor Agents; Vasopressins | 1971 |
[Blood pressure effects of noradrenaline and angiotensin in hypertensive and normotensive rats].
Topics: Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Norepinephrine; Rats | 1970 |
[Effect of preventive administration of reserpine on proteinuria induced with angiotensin in rats].
Topics: Angiotensin II; Animals; Hypertension; Proteinuria; Rats; Reserpine | 1971 |
[Effect of nephrectomy on serum protein changes induced with angiotensin in the rat].
Topics: Angiotensin II; Animals; Blood Proteins; Hypertension; Kidney; Nephrectomy; Rats | 1971 |
The etiology of hypertension.
Topics: Adrenal Medulla; Angiotensin II; Autonomic Nervous System; Blood Volume; Diet; Environment; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Pheochromocytoma; Renin; Sodium; Sodium Chloride | 1971 |
The progressive pressor response to angiotensin in the rabbit--the role of the sympathetic nervous system.
Topics: Angiotensin II; Animals; Blood Pressure; Brachiocephalic Trunk; Brain Stem; Central Nervous System; Cerebrovascular Circulation; Hypertension; Rabbits; Sympathetic Nervous System; Sympatholytics; Trimethaphan; Vertebral Artery | 1971 |
Baroreceptor reflex function in pre-eclampsia.
Topics: Angiotensin II; Arteries; Blood Pressure; Female; Humans; Hypertension; Phenylephrine; Pre-Eclampsia; Pregnancy; Pressoreceptors; Pulse; Reflex; Sleep | 1971 |
[Examination of angiotensin in hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Carbonates; Humans; Hypertension; Pyrrolidines; Rats | 1971 |
A review of plasma renin measurements and their clinical significance.
Topics: Angiotensin II; Animals; Carbon Isotopes; Humans; Hyperaldosteronism; Hypertension; Methods; Plasma; Radioimmunoassay; Rats; Renal Artery Obstruction; Renin | 1971 |
Hemodynamic effects of angiotensin in normal and environmentally stressed monkeys.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cerebrovascular Circulation; Coronary Vessels; Hemodynamics; Hypertension; Liver Circulation; Macaca; Male; Muscles; Posture; Radioisotope Dilution Technique; Regional Blood Flow; Skin; Stress, Physiological; Sympathetic Nervous System; Vascular Resistance; Vasomotor System | 1971 |
A comparative study of the cardiovascular reactivity in various hypertensive and in normotensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Desoxycorticosterone; Female; Hypertension; Norepinephrine; Rats | 1971 |
Vasoconstrictor in toxemia of pregnancy.
Topics: Angiotensin II; Diet; Eclampsia; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Thailand | 1971 |
[Comparative results of plasmatic renin determination and the angiotensin perfusion test in arterial hypertension].
Topics: Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Renin | 1971 |
[Orthostatic hypotension following cyclazenine medication].
Topics: Angiotensin II; Antihypertensive Agents; Electrocardiography; Ergoloid Mesylates; Ergotamine; Female; Heart Failure; Humans; Hypertension; Hypotension, Orthostatic; Methyldopa; Middle Aged; Norepinephrine; Phytotherapy; Piperidines; Plants, Medicinal; Pulmonary Edema; Rauwolfia; Sympatholytics | 1970 |
Determination of plasma renin concentration by angiotensin I immunoassay. Diagnotic import of precise measurement of subnormal renin in hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Aldosterone; Angiotensin II; Animals; Desoxycorticosterone; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Immunoassay; Iodine Radioisotopes; Methods; Renin; Sheep | 1971 |
Action of angiotensin and plasmakinins on blood flow through the mammary artery in unanesthetized lactating goats.
Topics: Angiotensin II; Animals; Bradykinin; Depression, Chemical; Dilatation; Female; Goats; Hypertension; Kallidin; Kallikreins; Mammary Glands, Animal; Regional Blood Flow; Thoracic Arteries | 1971 |
[Relationship between the renin-angiotensin-aldosterone system and CNS in the etiology of hypertension].
Topics: Aldosterone; Angiotensin II; Central Nervous System; Humans; Hypertension; Renin; Sympathetic Nervous System | 1971 |
Abnormal membrane sodium transport in Liddle's syndrome.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biological Transport; Cell Membrane; Child; Erythrocytes; Ethacrynic Acid; Female; Humans; Hypertension; Hypokalemia; In Vitro Techniques; Male; Osmolar Concentration; Ouabain; Potassium; Renal Tubular Transport, Inborn Errors; Renin; Sodium; Sodium Isotopes | 1971 |
[Importance of Kaplan's hypertension testing the etiologic diagnosis of hypertension].
Topics: Angiography; Angiotensin II; Chronic Disease; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Diseases; Methods; Renal Artery Obstruction; Renin | 1966 |
Renin in differential diagnosis of hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Blood Volume; Contraceptives, Oral; Depression, Chemical; Diagnosis, Differential; Estrogens; Female; Glomerular Filtration Rate; Humans; Hyperaldosteronism; Hypertension; Male; Posture; Radioimmunoassay; Renin; Sodium; Stimulation, Chemical | 1971 |
Influence of the carotid sinus on centrally mediated peripheral cardiovascular effects of angiotensin II.
Topics: Angiotensin II; Animals; Brain Chemistry; Cardiovascular System; Carotid Sinus; Cats; Denervation; Female; Hypertension; Male; Methods; Norepinephrine; Perfusion; Pressoreceptors; Regional Blood Flow | 1971 |
[Comparative gas chromatographic analysis of the FFA-pattern in the plasma in different models of hypertension in the rat].
Topics: Aldosterone; Angiotensin II; Animals; Chromatography, Gas; Disease Models, Animal; Fatty Acids, Nonesterified; Hypertension; Rats; Renin | 1971 |
[Humoral factors of renal cortex and medulla in complex system of blood pressure control].
Topics: Angiotensin II; Blood Pressure; Body Fluids; Humans; Hypertension; Hypertension, Renal; Kidney; Renin; Synaptic Transmission | 1971 |
[Relation of plasma renin activity and aldosterone excretion rate in angiotensin II-test and its diagnostic value in arterial hypertension patients].
Topics: Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Methods; Renin; Water-Electrolyte Balance | 1971 |
[The action of ST 155 (2,2,6-dichlorophenylamino-2-imidazoline hydrochloride) on the hypertensive crisis induced in the rat by administration of angiotensin II].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Hypertension; Imidazoles; Rats | 1971 |
[Clinical studies on the relation between aldosterone and various hypertensive and renal diseases. 2. Studies on the effect of synthetic angiotensin II on aldosterone secretion rate].
Topics: Addison Disease; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Injections, Intravenous; Liver Cirrhosis; Renal Artery Obstruction; Secretory Rate; Thyroiditis; Time Factors; Tritium | 1971 |
[Duplication of aortic wall cells in arterial hypertension].
Topics: Angiotensin II; Animals; Aorta; Cell Nucleus; Epithelial Cells; Hypertension; Mitosis; Rats; Thymidine; Tritium | 1970 |
Radio-fibrinogen studies in renal hypertension.
Topics: Acidosis; Anemia, Hemolytic; Angiotensin II; Animals; Aorta; Desoxycorticosterone; Disseminated Intravascular Coagulation; Female; Fibrinogen; Hemolysis; Hypertension; Hypertension, Renal; Hypoxia; Ligation; Methoxamine; Nephrectomy; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Rabbits; Rats; Renal Artery; Serum Albumin, Radio-Iodinated; Shock; Uremia | 1971 |
Renin response to diazoxide stimulation in experimental coarctation of the aorta.
Topics: Angiotensin II; Animals; Aortic Coarctation; Diazoxide; Dogs; Hypertension; Renin; Stimulation, Chemical | 1971 |
Arterial hypertension elicited by prolonged intra-vertebral infusion of angiotensin II in conscious dog.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Dogs; Female; Heart Rate; Hypertension; Infusions, Parenteral; Male; Vasomotor System; Vertebral Artery | 1971 |
Plasma renin activity in the rabbit with renal hypertension.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Cellophane; Homeostasis; Hypertension; Hypertension, Renal; Iodine Isotopes; Perinephritis; Rabbits; Radioimmunoassay; Renin | 1971 |
Role of the pressor action of angiotensin II in experimental hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Culture Techniques; Desoxycorticosterone; Disease Models, Animal; Hypertension; Hypertension, Renal; Male; Norepinephrine; Phenylephrine; Rabbits; Rats; Renin; Tyramine; Vasoconstrictor Agents; Vasopressins | 1971 |
Angiotensin II vascular receptors: their avidity in relationship to sodium balance, the autonomic nervous system, and hypertension.
Topics: Angiotensin II; Animals; Antibodies; Autonomic Nervous System; Blood Pressure; Desoxycorticosterone; Hypertension; Hypertension, Renal; Kidney; Male; Nephrectomy; Pressoreceptors; Rats; Sodium; Water-Electrolyte Balance | 1972 |
[Cardiovascular effects of alloxan].
Topics: Alloxan; Angiotensin II; Animals; Blood Pressure Determination; Cardiovascular System; Dogs; Electrocardiography; Epinephrine; Hypertension; Kidney; Vasomotor System | 1970 |
Ischemic heart disease and catecholamines.
Topics: Adult; Aged; Angina Pectoris; Angiotensin II; Blood Pressure; Catecholamines; Coronary Disease; Electrocardiography; Epinephrine; Exercise Test; Female; Heart Rate; Humans; Hypertension; Ischemia; Male; Middle Aged; Norepinephrine | 1971 |
[Effect of angiotensin II on arterial blood pressure, glomerular filtration rate and urinary sodium excretion in healthy rats, pregnant rats and rats with arterial hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Female; Glomerular Filtration Rate; Hypertension; Pregnancy; Rats; Sodium | 1971 |
[The effect of alpha methyldopa and spironolactone on angiotensin sensitivity in man].
Topics: Adult; Angiotensin II; Blood Pressure; Depression, Chemical; Drug Synergism; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Renin; Spironolactone; Stimulation, Chemical | 1972 |
Pressor responses in portacaval transposition.
Topics: Ammonia; Angiotensin II; Animals; Bilirubin; Blood Glucose; Blood Pressure; Blood Proteins; Blood Urea Nitrogen; Cholesterol; Dogs; Hypertension; Liver Function Tests; Norepinephrine; Portacaval Shunt, Surgical; Transaminases; Vasopressins | 1972 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1971 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Aldosterone; Angiotensin II; Animals; Humans; Hypertension; Renin | 1971 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Angiotensin II; Animals; Dogs; Hypertension; Hypertension, Renal; Rats; Renin | 1971 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1971 |
[Significance of renin-angiotensin system in the development of hypertension].
Topics: Angiotensin II; Humans; Hypertension; Hypertension, Renal; Renin | 1971 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Angiotensin II; Animals; Hypertension; Hypertension, Renal; Rats; Renin | 1971 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Angiotensin II; Glomerular Filtration Rate; Humans; Hypertension; Renin | 1971 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Angiotensin II; Animals; Hypertension; Hypertension, Renal; Rats; Renin | 1971 |
[Significance of renin-angiotensin system in the development of hypertension--author's comments and viewpoint].
Topics: Angiotensin II; Animals; Hypertension; Rats; Renin | 1971 |
[Renin-angiotensin system and hypertension--etiological significance].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1971 |
[The renin-angiotensin-aldosterone system. Disorders and methods of clinical research].
Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Aldosterone; Angiotensin II; Dexamethasone; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Methods; Mineralocorticoids; Pituitary-Adrenal Function Tests; Radioimmunoassay; Renin; Spironolactone | 1970 |
Chronic hypertension in rabbits induced by bilateral placement of rigid casts around the carotid sinus regions.
Topics: Angiotensin II; Animals; Blood Pressure; Carotid Artery, Internal; Carotid Sinus; Constriction; Dental Cements; Disease Models, Animal; Heart Rate; Hypertension; Rabbits; Reflex | 1972 |
Control of blood pressure.
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Blood Pressure; Hexamethonium Compounds; Humans; Hypertension; Methyldopa; Renin; Reserpine; Sodium Chloride; Sympatholytics | 1972 |
New thoughts on essential hypertension.
Topics: Angiotensin II; Cerebrovascular Disorders; Humans; Hypertension; Myocardial Infarction; Renin | 1972 |
Circulating levels of angiotensin in man measured by radioimmunoassay.
Topics: Adolescent; Adult; Angiotensin II; Female; Humans; Hypertension; Male; Methods; Radioimmunoassay | 1972 |
The response of blood pressure to infusion of angiotensin II: relation to plasma concentrations of renin and angiotensin II.
Topics: Angiotensin II; Blood Pressure; Contraceptives, Oral; Diet, Sodium-Restricted; Female; Humans; Hypertension; Hypertension, Renal; Hypotension, Orthostatic; Male; Renin; Sodium | 1972 |
Evidence for the existence of a sensitizing factor to pressor agents in the plasma of hypertensive patients.
Topics: Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney; Norepinephrine; Rats; Sodium; Stimulation, Chemical; Vasomotor System | 1972 |
Plasma desoxycorticosterone levels in man with simultaneous measurement of aldosterone, corticosterone, cortisol and 11-deoxycortisol.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Carbon Isotopes; Chromatography, Paper; Corticosterone; Cushing Syndrome; Desoxycorticosterone; Diet, Sodium-Restricted; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Radioisotope Dilution Technique; Tritium | 1972 |
Plasma renin concentration, activity and substrate in hypertension caused by oral contraceptives.
Topics: Adult; Angiotensin II; Animals; Contraceptives, Oral; Feedback; Female; Humans; Hypertension; Middle Aged; Posture; Radioimmunoassay; Renin; Sheep; Stimulation, Chemical; Time Factors | 1972 |
Renin reactivity in normal, hypertensive, and uremic plasma.
Topics: Angiotensin II; Animals; Depression, Chemical; Humans; Hypertension; Hypertension, Renal; In Vitro Techniques; Posture; Radioimmunoassay; Renin; Sheep; Stimulation, Chemical; Uremia | 1972 |
[Hypertension and hypertensive syndromes].
Topics: Adult; Aldosterone; Angiotensin II; Arteriosclerosis; Glomerulonephritis; Humans; Hypertension; Hypertension, Renal; Male; Middle Aged; Renin; Sodium | 1971 |
Drug modification of digital vascular reactivity to vasoactive substances.
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Blood Pressure; Dihydroxyphenylalanine; Fingers; Guanethidine; Humans; Hypertension; Hypertension, Renal; Norepinephrine; Prednisone; Raynaud Disease; Regional Blood Flow; Sodium Chloride; Spironolactone; Tyramine; Vasoconstrictor Agents; Vasodilator Agents | 1969 |
Mesenteric microcirculation in rats with experimental hypertension.
Topics: Angiotensin II; Animals; Arteries; Constriction; Desoxycorticosterone; Ephedrine; Epinephrine; Hypertension; Hypertension, Renal; Mesentery; Methods; Microcirculation; Rats; Serotonin; Sodium Chloride; Veins | 1969 |
[The morphology of pancreatic islet cells following experimentally induced blood pressure dysregulation in rats].
Topics: Angiotensin II; Animals; Cytoplasmic Granules; Electrocoagulation; Humans; Hypertension; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nephrectomy; Pressoreceptors; Rats; Rats, Inbred Strains; Stress, Psychological | 1971 |
[Neurotically induced hypertensive blood pressure reactions and the effect of additional interventions into the intermeshed regulatory system of blood pressure homeostasis in albino rats].
Topics: Acoustic Stimulation; Angiotensin II; Animals; Corticosterone; Electric Stimulation; Female; Hemodynamics; Humans; Hypertension; Male; Neurotic Disorders; Photic Stimulation; Rats; Rats, Inbred Strains; Reaction Time; Stress, Psychological; Water Deprivation | 1971 |
Arterial pressure regulation. Overriding dominance of the kidneys in long-term regulation and in hypertension.
Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output; Electrolytes; Humans; Hypertension; Hypertension, Renal; Kidney; Medulla Oblongata; Pressoreceptors; Renin; Stress, Physiological; Vascular Resistance; Water | 1972 |
Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Body Weight; Extracellular Space; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Postoperative Care; Potassium; Renin; Sodium; Spironolactone; Urea | 1972 |
Measurement of angiotensin II in blood by radioimmunoassay.
Topics: Angiotensin II; Animals; Chromatography, Gel; Chromatography, Ion Exchange; Contraceptives, Oral; Dogs; Electrophoresis, Paper; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Iodine Isotopes; Isotope Labeling; Kidney; Methods; Nephrectomy; Potassium Iodide; Rabbits; Radioimmunoassay; Renin; Sheep; Swine | 1972 |
Improved technique for radioimmunoassay of angiotensin II in plasma.
Topics: Angiotensin II; Capillaries; Chromatography, Thin Layer; Cross Reactions; Humans; Hypertension; Iodine Isotopes; Methods; Nephrectomy; Radioimmunoassay | 1972 |
Low renin hypertension and the adrenal cortex.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Corticosterone; Desoxycorticosterone; Diuresis; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokalemia; Indoles; Male; Pyridines; Renin; Secretory Rate; Spironolactone; Sulfonic Acids | 1972 |
Cardiovascular and renal effects of acute administration of a new hypotensive compound, guancydine.
Topics: Administration, Oral; Aminohippuric Acids; Angiotensin II; Blood Pressure; Glomerular Filtration Rate; Guanidines; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Kidney Function Tests; Nitriles; Norepinephrine; Posture; Potassium; Sodium; Water-Electrolyte Balance | 1971 |
[Renin and renin substrate in pregnancy].
Topics: Angiotensin II; Enzyme Precursors; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Renin | 1972 |
Volume control.
Topics: Aldosterone; Angiotensin II; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Natriuresis; Norepinephrine; Posture; Potassium | 1972 |
[Kidney and hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Extracellular Space; Humans; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Natriuresis; Nephrectomy; Plasma Volume; Rabbits; Rats; Renal Artery Obstruction; Renin; Sodium; Transplantation, Homologous; Water | 1972 |
Heart attacks: possible risk factor.
Topics: Adrenal Cortex Hormones; Angiotensin II; Arteriosclerosis; Blood Vessels; Humans; Hypertension; Hypertension, Malignant; Myocardial Infarction; Renin | 1972 |
[Cardiovascular effects of angiotensin II implantates on the intact unanesthesized rat. A contribution to produce a medium-term experimental hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Heart Rate; Hypertension; Male; Rats; Rats, Inbred Strains; Time Factors | 1972 |
[Value of plasma renin activity determination in clinical practice].
Topics: Angiotensin II; Animals; Humans; Hypertension; Methods; Rats; Renin | 1972 |
[Renin-angiotensin-aldosterone system in water-electrolyte homeostasis].
Topics: Aldosterone; Angiotensin II; Autonomic Nervous System; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Renin; Sodium; Water; Water-Electrolyte Balance | 1972 |
Blood pressure response and antibody formation in spontaneously hypertensive rats and normal albino rats after immunization against angiotensin II.
Topics: Angiotensin II; Animals; Antibody Formation; Blood Pressure; Hypertension; Immunization; Iodine Isotopes; Male; Radioimmunoassay; Rats; Species Specificity | 1972 |
Definition and use of renin reaction velocity in the study of human hypertension.
Topics: Angiotensin II; Animals; Aorta; Ethinyl Estradiol; Female; Humans; Hydrogen-Ion Concentration; Hypertension; Hypertension, Renal; Male; Methods; Nephrectomy; Norethindrone; Rats; Renal Veins; Renin; Temperature; Time Factors | 1972 |
Oral contraceptive hypertension.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Kidney; Pregnancy; Pregnancy Complications, Cardiovascular; Prognosis; Renin; Sodium | 1972 |
Metabolism of angiotensin II in sodium depletion and hypertension in humans.
Topics: Angiotensin II; Female; Humans; Hypertension; Iodine Isotopes; Male; Metabolic Clearance Rate; Middle Aged; Radioimmunoassay; Renin; Sodium | 1972 |
The renin-angiotensin-aldosterone system in normotensive and hypertensive patients with acromegaly.
Topics: Acromegaly; Adolescent; Adult; Aldosterone; Angiotensin II; Blood Volume; Female; Growth Hormone; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Plasma Volume; Potassium; Radioimmunoassay; Renin; Secretory Rate; Sodium | 1972 |
Arteriovenous fistulae in rabbit kidney studied by dye-dilution technique and by angiography.
Topics: Anesthesia, Intravenous; Aneurysm; Angiography; Angiotensin II; Animals; Arteriovenous Fistula; Blood Pressure Determination; Dye Dilution Technique; Hypertension; Ischemia; Kidney; Norepinephrine; Phentolamine; Punctures; Rabbits; Spectrophotometry; Thrombosis; Trimethaphan; Urinary Catheterization; Vasopressins | 1972 |
Some relations connecting angiotensin, catecholamines and hypertension.
Topics: Angiotensin II; Animals; Catecholamines; Hypertension; Rats; Vasomotor System | 1972 |
Angiotensin, hypertension and vascular ionic composition.
Topics: Angiotensin II; Animals; Arteries; Dogs; Hypertension; Water-Electrolyte Balance | 1972 |
How an acute rise in arterial pressure damages arterioles. Electron microscopic changes during angiotensin infusion.
Topics: Angiotensin II; Animals; Arteries; Basement Membrane; Blood Platelets; Capillary Permeability; Carbon; Constriction; Dilatation; Epithelial Cells; Hydralazine; Hypertension; Male; Microscopy, Electron; Muscle, Smooth; Nephrectomy; Rats; Time Factors | 1972 |
[Influence of angiotensin on the excretion of vanilmandelic acid in patients with juvenile hypertension].
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Humans; Hypertension; Sympathetic Nervous System; Vanilmandelic Acid | 1972 |
The control of aldosterone secretion in normal and hypertensive man: abnormal renin-aldosterone patterns in low renin hypertension.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Potassium; Renin; Sodium | 1972 |
Induced hypertension in the treatment of severe ischemia of the foot.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Female; Foot; Gangrene; Humans; Hypertension; Ischemia; Male; Middle Aged; Plethysmography; Posture | 1972 |
Primary reninism. Hypertension, hyperreninemia, and secondary aldosteronism due to renin-producing juxtaglomerular cell tumors.
Topics: Adolescent; Angiotensin II; Circadian Rhythm; Fluorescent Antibody Technique; Humans; Hyperaldosteronism; Hypertension; Juxtaglomerular Apparatus; Kidney Neoplasms; Male; Microscopy, Electron; Posture; Renin; Sodium; Syndrome | 1972 |
[Essential permanent arterial hypertension. Probability of a neurogenic factor].
Topics: Adult; Angiotensin II; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Hypotension, Orthostatic; Male; Norepinephrine; Plasma Volume; Posture; Vascular Resistance; Vasomotor System | 1972 |
Renin, angiotensin II, and adrenal corticosteroid relationships during sodium deprivation and angiotensin infusion in normotensive and hypertensive man.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Corticosterone; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Renin; Sodium; Water-Electrolyte Balance | 1972 |
Central action of angiotensin and hypertension--increased central vasomotor outflow by angiotensin.
Topics: Angiotensin II; Animals; Atropine; Blood Pressure; Dogs; Guanethidine; Heart; Hypertension; Kidney; Splanchnic Nerves; Sympathetic Nervous System; Vasomotor System | 1972 |
The mechanism of estrogen hypertension.
Topics: Angiotensin II; Animals; Biological Assay; Blood Pressure; Body Weight; Estrogens; Hypertension; Kidney; Male; Rats; Renin | 1972 |
[Measurement of plasma renin activity by angiotensin I radioimmunoassay--a modification of Haber's method].
Topics: Adolescent; Adult; Angiotensin II; Antibodies; Charcoal; Chromatography, Gel; Female; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hypertension; Hypertension, Renal; Iodine Isotopes; Male; Methods; Middle Aged; Radioimmunoassay; Renin | 1972 |
[Blood pressure dynamics in the albino rat in combination with exteroreceptive stimulation factors and administration of angiotensin II].
Topics: Acoustic Stimulation; Angiotensin II; Animals; Blood Pressure; Hypertension; Male; Photic Stimulation; Rats | 1972 |
A pressor substance in the cerebrospinal fluid of normotensive and hypertensive patients.
Topics: Adolescent; Adult; Aged; Angiotensin II; Animals; Biological Assay; Blood Pressure; Chromatography, Gel; Female; Humans; Hypertension; Hypertension, Malignant; Ileum; Male; Middle Aged; Nephrectomy; Radioimmunoassay; Rats; Uterus; Vasoconstrictor Agents | 1972 |
Clinical usefulness of evaluation the renin-angiotensin system in hypertension.
Topics: Angiotensin II; Circadian Rhythm; Diuretics; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Posture; Renin; Sodium | 1972 |
Angiotensin II plasma levels in hypertensive patients.
Topics: Adenoma; Adrenal Gland Neoplasms; Angiotensin II; Female; Furosemide; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Iodine Isotopes; Kidney Diseases; Posture; Radioimmunoassay; Renal Artery Obstruction; Renal Veins; Stimulation, Chemical | 1972 |
Assay of plasma renin activity using commercially available reagents.
Topics: Angiotensin II; Binding Sites, Antibody; Blood Proteins; Charcoal; Dialysis; Dimercaprol; Drug Stability; Edetic Acid; Hot Temperature; Humans; Hydrogen-Ion Concentration; Hypertension; Hypertension, Renal; Indicators and Reagents; Iodine Isotopes; Kidney Diseases; Kidney Transplantation; Peptides; Quinolines; Radioimmunoassay; Renin; Sodium; Time Factors; Transplantation, Homologous | 1972 |
Renin in rats with spontaneous hypertension.
Topics: Age Factors; Angiotensin II; Animals; Biological Assay; Body Weight; Hypertension; Kidney; Rats; Renin | 1972 |
[The pathogenesis of hypertension].
Topics: Adrenal Medulla; Angiotensin II; Catecholamines; Humans; Hypertension; Kallikreins; Kidney; Kinins; Physical Exertion; Sympathetic Nervous System | 1972 |
Angiotensin I assays.
Topics: Aged; Angiotensin II; Female; Humans; Hypertension; Kidney Diseases; Pregnancy | 1973 |
[New data on hormone-dependent hypertension and their significance for the practice].
Topics: Angiotensin II; Catecholamines; Cushing Syndrome; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Male; Renin | 1973 |
[Comparison between radioimmunological and biological determination of plasma renin activity].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biological Assay; Edetic Acid; Humans; Hydrogen-Ion Concentration; Hypertension; Infant, Newborn; Iodine Isotopes; Kinetics; Methods; Protease Inhibitors; Quinolines; Radioimmunoassay; Renin | 1972 |
Plasma renin activity and blood pressure in 89 patients receiving maintenance haemodialysis therapy.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Body Weight; Child; Child, Preschool; Diet; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Nephrectomy; Renal Dialysis; Renin; Sodium; Time Factors | 1972 |
Changes of blood pressure, renin, and angiotensin after bilateral nephrectomy in patients with chronic renal failure.
Topics: Adolescent; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Chronic Disease; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Nephrectomy; Renal Dialysis; Renin | 1972 |
[Orthostatic changes of plasma renin levels, circulatory mechanics and kidney function as well as of plasma catecholamines in normal individuals and patients with essential hypertension].
Topics: Angiotensin II; Catecholamines; Hemodynamics; Humans; Hypertension; Kidney; Male; Posture; Renin | 1971 |
[Development of connective tissue proliferation in the myocardium following the effect of various pathogenic stimuli].
Topics: Angiotensin II; Animals; Cardiomyopathies; Cell Division; Connective Tissue; Humans; Hypertension; Myocardium; Rats; Rats, Inbred Strains; Stress, Psychological; Tritium | 1971 |
Determination of plasma renin activity by radioimmunoassay of angiotensin I.
Topics: Adolescent; Adult; Angiotensin II; Animals; Biological Assay; Chronic Disease; Edetic Acid; Glomerulonephritis; Hot Temperature; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hypertension; Hypertension, Renal; Iodine Isotopes; Isoflurophate; Methods; Middle Aged; Rabbits; Radioimmunoassay; Renin; Serum Albumin | 1973 |
Activity of plasma angiotensin II in experimental coarctation of the aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Coarctation; Blood Pressure; Carotid Sinus; Constriction; Dogs; Electric Stimulation; Heart Rate; Hypertension | 1973 |
Primary aldosteronism due to hyperplasia of zona glomerulosa: failure of suppression by DOCA or stimulation by angiotensin.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Angiotensin II; Desoxycorticosterone; Glucose Tolerance Test; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Prognosis; Stimulation, Chemical | 1972 |
[Hemodialysis and hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Kidney Failure, Chronic; Renal Dialysis; Renin | 1972 |
Changes in renin kinetics induced by nephrectomy.
Topics: Angiotensin II; Animals; Blood Chemical Analysis; Hydrogen-Ion Concentration; Hypertension; Kinetics; Male; Nephrectomy; Rats; Renin; Swine | 1972 |
[Radioimmunological detection of angiotensin I and II for functional diagnostics of the renin-angiotensin system in various types of hypertension].
Topics: Angiotensin II; Humans; Hypertension; Radioimmunoassay; Renin | 1972 |
Accelerated hypertension secondary to oral contraceptives.
Topics: Aldosterone; Angiotensin II; Contraceptives, Oral; Estrogens; Female; Humans; Hypertension; Renin | 1973 |
Renin-angiotensin system and hypertension.
Topics: Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Renin | 1972 |
Hypertension with aldosterone excess.
Topics: Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Renin | 1972 |
[Participation of aortic arch and carotid sinus baroreceptors in acute pressor reactions in experimental renal hypertension].
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Carotid Sinus; Electric Stimulation; Hypertension; Hypertension, Renal; Norepinephrine; Pressoreceptors; Rabbits; Reflex; Reticular Formation | 1972 |
Estimation of angiotensin II blood concentrations in hypertensive rats.
Topics: Angiotensin II; Animals; Biological Assay; Colon; Hypertension; In Vitro Techniques; Methods; Rats | 1972 |
Effect of angiotensin II on plasma free fatty acids in hypertensive subjects with and without overweight.
Topics: Adipose Tissue; Adult; Aged; Angiotensin II; Blood Pressure; Body Weight; Fatty Acids, Nonesterified; Female; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged; Time Factors | 1973 |
Low-renin hypertension.
Topics: Angiotensin II; Black People; Cerebrovascular Disorders; Humans; Hypertension; Myocardial Infarction; Radioimmunoassay; Renin; Sodium | 1973 |
Effect of oral contraceptive therapy on the renin-angiotensin system in normotensive and hypertensive women.
Topics: Adult; Angiotensin II; Blood Pressure; Contraceptives, Oral; Endopeptidases; Female; Humans; Hypertension; Kidney; Middle Aged; Renin | 1973 |
[Essential hypertension: biochemical analysis--selective treatment].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Propranolol; Renin; Sodium | 1973 |
[Regulation of the renin-angiotensin system].
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin | 1973 |
Plasma volume, extracellular fluid volume and exchangeable sodium concentrations in the New Zealand strain of genetically hypertensive rat.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Chromium Isotopes; Extracellular Space; Hematocrit; Hypertension; Indicator Dilution Techniques; Plasma Volume; Potassium; Rats; Rats, Inbred Strains; Renin; Sodium | 1973 |
Angiotensin, aldosterone and DOC in hypertensive disease of pregnancy.
Topics: Aldosterone; Angiotensin II; Desoxycorticosterone; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Radioimmunoassay; Renin | 1973 |
[Arterial hypertension and mineralocorticoids].
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Cortisone; Cushing Syndrome; Female; Glomerular Filtration Rate; Glucocorticoids; Homeostasis; Humans; Hydrocortisone; Hyperaldosteronism; Hypertension; Hypertension, Renal; Mineralocorticoids; Renin | 1973 |
[Oral contraceptives and hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Contraceptives, Oral; Female; Humans; Hypertension; Renin | 1973 |
A possible etiology of contractility impairment of vascular smooth muscle from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Barium; Blood Pressure; Calcium; Cobalt; Hypertension; In Vitro Techniques; Lanthanum; Manganese; Muscle Contraction; Muscle, Smooth; Nitroglycerin; Norepinephrine; Organ Size; Ouabain; Papaverine; Potassium; Rats; Strontium; Vasoconstrictor Agents | 1973 |
Baroreceptor activity in normotensive and hypertensive uremic patients.
Topics: Adult; Amyl Nitrite; Angiotensin II; Blood Pressure; Blood Proteins; Electrocardiography; Hematocrit; Humans; Hypertension; Iodine Isotopes; Nephrectomy; Plasma Volume; Posture; Pressoreceptors; Pulse; Renal Dialysis; Respiration; Sodium; Time Factors; Uremia | 1973 |
Contraceptive conundrum. II. Hypertension.
Topics: Adult; Angiotensin II; Contraceptives, Oral; Estrogens, Conjugated (USP); Feedback; Female; Humans; Hypertension; Hypertension, Malignant; Renin | 1973 |
Unilateral ureteral obstruction. A caue of reversible high renin content hypertension.
Topics: Adult; Angiotensin II; Aorta, Abdominal; Aortography; Humans; Hypertension; Kidney Pelvis; Male; Renin; Time Factors; Ureteral Obstruction; Urography; Vena Cava, Inferior | 1973 |
Genetic influence on the renin-angiotensin system: low renin activities in hypertension-prone rats.
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Kidney; Rats; Renin; Sodium Chloride; Statistics as Topic | 1973 |
Plasma renin studies in patients with traumatic spinal cord injuries.
Topics: Adult; Angiotensin II; Creatinine; Diet, Sodium-Restricted; Humans; Hypertension; Male; Middle Aged; Paraplegia; Posture; Proteinuria; Pyelonephritis; Quadriplegia; Renin; Sodium; Sodium Chloride; Spinal Cord Injuries; Time Factors | 1973 |
Radioimmunoassay for plasma renin activity.
Topics: Angiotensin II; Blood Proteins; Female; Humans; Hydrogen-Ion Concentration; Hypertension; Male; Radioimmunoassay; Renal Artery Obstruction; Renin | 1973 |
[Stimulation and suppression of angiotension I and II in arterial hypertension].
Topics: Angiotensin II; Depression, Chemical; Furosemide; Humans; Hypertension; Sodium; Stimulation, Chemical | 1972 |
Time course of decrease in blood pressure and in blood pressure response to vasopressor agents during pregnancy in the rat.
Topics: Acetylcholine; Aldosterone; Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Female; Hypertension; Hypertension, Renal; Norepinephrine; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Renin; Time Factors; Tyramine; Vasoconstrictor Agents | 1973 |
[Relationship between neurotically induced hypertension and the contents of pancreatic B-cell granules in albino rats].
Topics: Angiotensin II; Animals; Blood Glucose; Carbohydrate Metabolism; Cytoplasmic Granules; Female; Humans; Hypertension; Islets of Langerhans; Male; Prediabetic State; Rats; Rats, Inbred Strains; Statistics as Topic; Stress, Psychological | 1973 |
[Renin-angiotensin-aldosterone system in hyperthyroidism].
Topics: Aldosterone; Angiotensin II; Female; Furosemide; Humans; Hypertension; Hyperthyroidism; Hypopituitarism; Hypothyroidism; Myxedema; Posture; Renin | 1973 |
[Studies on rats with long-term resistance hypertension induced by daily administration of delayed-action preparations of angiotensin].
Topics: Angiotensin II; Animals; Blood Pressure; Delayed-Action Preparations; Disease Models, Animal; Hypertension; Injections, Subcutaneous; Male; Rats; Time Factors | 1973 |
Elevated circulating renin activity in rats following doses of cadmium known to induce hypertension.
Topics: Administration, Oral; Angiotensin II; Animals; Blood Pressure; Cadmium; Female; Hypertension; Injections, Intraperitoneal; Lead; Mercury; Rats; Renin; Time Factors; Zinc | 1973 |
[Studies of the free fatty acid pattern in blood plasma in experimental neurogenic-interoceptive hypertension and during administration of angiotension II in the rabbit].
Topics: Angiotensin II; Animals; Blood Pressure; Carotid Artery Diseases; Carotid Sinus; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Hypertension; Lipid Metabolism; Male; Oleic Acids; Palmitic Acids; Pressoreceptors; Rabbits | 1973 |
Renal failure, uncontrollable thirst, and hyperreninemia. Cessation of thirst with bilateral nephrectomy.
Topics: Angiotensin II; Humans; Hypertension; Hyponatremia; Hypothalamus; Kidney Failure, Chronic; Male; Middle Aged; Nephrectomy; Renal Dialysis; Renin; Thirst; Time Factors | 1973 |
[Contribution of hemodynamic studies to the diagnosis and treatment of arterial hypertension].
Topics: Angiotensin II; Antihypertensive Agents; Blood Volume Determination; Body Surface Area; Cardiac Output; Humans; Hypertension; Posture; Renin | 1973 |
[Qualitative changes in prostaglandins in kidneys of normotonic and hypertonic animals under the effect of aspirin-like preparations].
Topics: Angiotensin II; Animals; Aspirin; Blood Pressure; Hypertension; Indomethacin; Prostaglandins; Rats; Secretory Rate | 1972 |
Editorial: New knowledge of benign essential hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Ethnicity; Humans; Hypertension; Propranolol; Renin; Spironolactone | 1973 |
Renin in hypertension: how important as a risk factor?
Topics: Adult; Angiotensin II; Aortic Aneurysm; Aortic Rupture; Blood Pressure; Cerebrovascular Disorders; Creatinine; Follow-Up Studies; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Middle Aged; Myocardial Infarction; Posture; Potassium; Renal Artery Obstruction; Renin; Sodium; Urea | 1973 |
Renin-angiotensin system during labor: evaluation of renin activity in normal, pre-eclamptic, and pre-existing hypertensive patients.
Topics: Angiotensin II; Female; Humans; Hypertension; Iodine Radioisotopes; Muscle Contraction; Obstetric Labor Complications; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Protease Inhibitors; Radioimmunoassay; Regional Blood Flow; Renin; Uterus | 1973 |
Hypertension in terminal renal failure. Observations pre and post bilateral nephrectomy.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Eye Manifestations; Female; Fundus Oculi; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Kidney Failure, Chronic; Male; Middle Aged; Nephrectomy; Norepinephrine; Renal Dialysis; Renin; Time Factors | 1973 |
Vasoconstriction-volume analysis for understanding and treating hypertension: the use of renin and aldosterone profiles.
Topics: Aldosterone; Angiotensin II; Arteries; Blood Pressure; Diuretics; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Prognosis; Propranolol; Renin | 1973 |
Searching out low renin patients: limitations of some commonly used methods.
Topics: Angiotensin II; Blood; Dimercaprol; Edetic Acid; Humans; Hydrogen-Ion Concentration; Hypertension; Isoflurophate; Methods; Neomycin; Quinolines; Radioimmunoassay; Renin; Temperature; Time Factors | 1973 |
Neurogenic factors in human hypertension: mechanism or myth?
Topics: Angiotensin II; Blood Pressure; Catecholamines; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Epinephrine; Humans; Hypertension; Hypertension, Renal; Male; Nervous System Diseases; Norepinephrine; Pargyline; Physical Exertion; Posture; Reserpine; Sympathetic Nervous System; Tritium | 1973 |
Hypertension in chronic renal failure. An abnormal relation between sodium and the renin-angiotensin system.
Topics: Angiotensin II; Blood Pressure; Drug Interactions; Humans; Hypertension; Hypertension, Malignant; Kidney Failure, Chronic; Nephrectomy; Renal Dialysis; Renin; Sodium | 1973 |
The renin axis in causation, prognosis and treatment of hypertensive disease.
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Prognosis; Renin | 1973 |
Clinical conference: Essential hypertension: new concepts about mechanisms.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Humans; Hydroxycorticosteroids; Hypertension; Kidney; Middle Aged; Progesterone; Renin | 1973 |
A study of angiotensin II pressor response throughout primigravid pregnancy.
Topics: Adolescent; Angiotensin II; Blood Pressure; Eclampsia; Female; Humans; Hypertension; Injections, Intravenous; Parity; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria; Vascular Resistance | 1973 |
Altered ion transport in vascular smooth muscle from spontaneously hypertensive rats. Influences of aldosterone, norepinephrine, and angiotensin.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Aorta; Aorta, Thoracic; Blood Pressure; Chlorides; Chlorine; Cobalt Radioisotopes; Corticosterone; Electrolytes; Hypertension; In Vitro Techniques; Male; Muscle, Smooth; Norepinephrine; Potassium; Potassium Isotopes; Radioisotopes; Rats; Sodium | 1973 |
Plasma renin activity in segmental hypoplasia of the kidneys with hypertension.
Topics: Adolescent; Angiotensin II; Blood Pressure; Blood Urea Nitrogen; Cell Count; Child; Creatinine; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Kidney; Male; Posture; Renal Veins; Renin; Time Factors | 1973 |
Reactivity of vascular smooth muscle in hypertensive rats.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Body Weight; Calcium; Cell Membrane; Desoxycorticosterone; Epinephrine; Femoral Artery; Hypertension; Hypertension, Renal; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Rats; Stimulation, Chemical; Strontium; Tachyphylaxis | 1973 |
[On adrenal tumors and hypertensinogenic retroperitoneal tumors].
Topics: Adenocarcinoma; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Angiotensin II; Carcinoma; Catecholamines; Child; Female; Humans; Hypertension; Hypertension, Renal; Lymphangioma; Male; Middle Aged; Neuroblastoma; Pheochromocytoma; Renal Artery Obstruction; Retroperitoneal Neoplasms | 1973 |
[Franz Volhard--the red and pale high pressure in the modern viewpoint. 1].
Topics: Angiotensin II; Animals; Dogs; Germany; History, 20th Century; History, Modern 1601-; Humans; Hypertension; Kidney Diseases; Rabbits; Renin | 1973 |
Systems analysis of arterial pressure regulation and hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Capillary Permeability; Cardiac Output; Chemoreceptor Cells; Computers; Dogs; Feedback; Humans; Hypertension; Kidney; Medulla Oblongata; Models, Biological; Oxygen; Pressoreceptors; Renin; Sodium Chloride; Systems Analysis; Vascular Resistance | 1972 |
[Activity of renin in blood plasma of patients with arterial hypertension].
Topics: Adult; Aged; Angiotensin II; Blood Volume; Cardiac Output; Circadian Rhythm; Dopamine; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis; Posture; Potassium; Pulse; Renin; Sodium | 1973 |
Effect of furosemide administration and upright position on plasma renin activity and angiotensin II in hypertension.
Topics: Angiotensin II; Cushing Syndrome; Enzyme Activation; Furosemide; Glomerulonephritis; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Posture; Radioimmunoassay; Renal Artery Obstruction; Renin | 1973 |
Renal function in pregnancy.
Topics: Aldosterone; Angiotensin II; Catecholamines; Estrogens; Female; Glomerular Filtration Rate; Glycosuria; Humans; Hypertension; Kidney; Kidney Concentrating Ability; Natriuresis; Posture; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Infectious; Regional Blood Flow; Renin; Sodium; Specimen Handling; Uric Acid; Urinary Tract Infections; Urinary Tract Physiological Phenomena; Urine | 1972 |
Hypertension: a disease of abnormal circulatory control.
Topics: Angiotensin II; Blood Pressure; Cardiac Output; Diuresis; Glomerular Filtration Rate; Humans; Hyperaldosteronism; Hypertension; Kidney; Kidney Glomerulus; Kidney Tubules; Membranes; Organ Size; Time Factors; Vascular Resistance; Water-Electrolyte Balance | 1974 |
[Water and electrolyte imbalance and the renin-angiotensin-aldosterone system].
Topics: Aldosterone; Angiotensin II; Animals; Dogs; Electrolytes; Humans; Hypertension; Male; Middle Aged; Potassium; Rats; Renin; Sodium; Water-Electrolyte Balance | 1973 |
Arterial hypertension induced by 9 alpha-fluorocortisol in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Depression, Chemical; Eating; Fludrocortisone; Heart; Hematocrit; Hypertension; Injections, Intramuscular; Kidney; Male; Nephrectomy; Organ Size; Potassium; Rats; Renin; Sodium; Sodium Chloride; Stimulation, Chemical; Time Factors; Water-Electrolyte Balance | 1974 |
[Pregnancy toxemia. Recent data].
Topics: Aldosterone; Angiotensin II; Disseminated Intravascular Coagulation; Estriol; Female; Fetal Death; Fetoscopy; Humans; Hypertension; Ischemia; Pre-Eclampsia; Pregnancy; Prognosis; Renin | 1974 |
Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.
Topics: Adrenocortical Hyperfunction; Amiloride; Angiotensin II; Body Water; Corticosterone; Diuretics; Extracellular Space; Humans; Hyperaldosteronism; Hypertension; Plasma Volume; Potassium; Pyrazines; Renin; Secretory Rate; Sodium; Spironolactone; Urea | 1973 |
Metabolic clearance rate of angiotensin II in arterial hypertension.
Topics: Addison Disease; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Iodine Isotopes; Kidney Failure, Chronic; Metabolic Clearance Rate | 1973 |
Angiotensin-salt hypertension.
Topics: Angiotensin II; Animals; Body Fluids; Body Weight; Diet, Sodium-Restricted; Hypertension; Kidney Medulla; Rats; Sodium Chloride; Spironolactone; Transplantation, Homologous | 1973 |
Plasma renin activity and plasma renin substrate in hypertension associated with steroid excess.
Topics: Angiotensin II; Contraceptives, Oral; Cushing Syndrome; Female; Glucocorticoids; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hypertension; Kinetics; Radioimmunoassay; Renin | 1973 |
Oral contraceptives and hypertension.
Topics: Adult; Angiotensin II; Blood Pressure Determination; Contraceptives, Oral; Female; Humans; Hypertension; Middle Aged; Renin | 1973 |
Hormonal profiling in the diagnosis and treatment of essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Middle Aged; Propranolol; Renin; Sodium | 1974 |
[Recent contributions to the study of arterial hypertension].
Topics: Aldosterone; Angiotensin II; Endopeptidases; Humans; Hypertension; Hypertension, Malignant; Renin | 1974 |
Comparison of hemodynamic responses to exercise in hypertensive patients and in healthy subjects given angiotensin.
Topics: Adult; Angiotensin II; Blood Pressure; Body Surface Area; Brachial Artery; Cardiac Output; Dye Dilution Technique; Heart Rate; Hemodynamics; Humans; Hypertension; Infusions, Parenteral; Male; Methods; Middle Aged; Physical Exertion; Respiration; Time Factors; Vascular Resistance | 1973 |
Acute hypertension and prolonged focal cerebral ischemia.
Topics: Angiotensin II; Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Ischemic Attack, Transient; Rabbits | 1973 |
[Editorial: Renin, angiotensin and hypertension].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1974 |
[How to advance antihypertensive therapy].
Topics: Adult; Angiotensin II; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clonidine; Humans; Hypertension; Methyldopa; Middle Aged; Mineralocorticoid Receptor Antagonists; Prostaglandins; Renin; Spironolactone; Time Factors | 1974 |
[Proteinuria caused by angiotensin: blood protein clearance].
Topics: Angiotensin II; Animals; Blood Pressure; Blood Proteins; Hypertension; Proteinuria; Rats | 1973 |
Plasma renin concentration: comparison of angiotensinase inhibitors and correlation with plasma renin activity and aldosterone.
Topics: Aldosterone; Angiotensin II; Dimercaprol; Humans; Hydrogen-Ion Concentration; Hypertension; Methods; Protease Inhibitors; Quinolines; Radioimmunoassay; Renin | 1974 |
[Diagnosis and therapy of arterial hypertension. Significance of the renin-angiotensin-aldosterone system in differential diagnosis and therapy].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Antihypertensive Agents; Diagnosis, Differential; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Renin | 1974 |
Simultaneous measurements in awake rats of drug-induced changes in carotid and tail-cuff systolic pressures.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Carotid Arteries; Catheterization; Female; Humans; Hypertension; Norepinephrine; Pentolinium Tartrate; Phentolamine; Rats; Tail | 1974 |
Upper limit of autoregulation of cerebral blood flow in the baboon.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain Diseases; Cerebrovascular Circulation; Cerebrovascular Disorders; Homeostasis; Hypertension; Papio; Radioisotopes; Sympathectomy; Vascular Resistance; Vasomotor System; Xenon | 1974 |
Ontogenesis of the renin-angiotensin system in spontaneously hypertensive and normal Wistar rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Aorta; Blood; Blood Pressure; Female; Gestational Age; Hypertension; Juxtaglomerular Apparatus; Kidney; Methods; Pregnancy; Pregnancy, Animal; Radioimmunoassay; Rats; Renin; Sheep | 1974 |
A contrast in vascular reactivity between two kinds of experimental hypertension studied by measurements of the critical opening pressure of tail vessels in the conscious rat.
Topics: Angiotensin II; Animals; Arteries; Desoxycorticosterone; Dose-Response Relationship, Drug; Hypertension; Hypertension, Renal; Male; Microcirculation; Muscle, Smooth; Norepinephrine; Oxyhemoglobins; Pressure; Rats; Sodium Chloride; Spectrum Analysis; Tail; Vasomotor System | 1973 |
[Pathophysiological aspects of hypertension (author's transl)].
Topics: Adaptation, Physiological; Angiotensin II; Animals; Cardiac Volume; Heart Rate; Hypertension; Hypertension, Renal; Male; Psychosocial Deprivation; Rats; Renin; Sodium; Vascular Resistance | 1974 |
The nature of pressor responsiveness to angiotensin II in human pregnancy.
Topics: Angiotensin II; Blood Pressure; Blood Specimen Collection; Dextrans; Dose-Response Relationship, Drug; Female; Hematocrit; Humans; Hypertension; Infusions, Parenteral; Injections, Intravenous; Models, Biological; Plasma Volume; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Sodium Chloride; Vascular Resistance | 1974 |
[The evaluation of arterial hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Blood Sedimentation; Electrocardiography; Humans; Hypertension; Kidney; Renin | 1974 |
Response of plasma aldosterone to postural change, diuretica, angiotensin II, sodium restriction or loading and prostaglandin.
Topics: Adrenocortical Hyperfunction; Aldosterone; Angiotensin II; Ascites; Cushing Syndrome; Diet; Diet, Sodium-Restricted; Furosemide; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Liver Cirrhosis; Posture; Prostaglandins; Radioimmunoassay; Sodium; Uremia | 1973 |
[Primary and secondary aldosteronism in hypertension].
Topics: Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Renin | 1974 |
[Efficacy and limits of diagnostic procedures in hypertension].
Topics: Angiography; Angiotensin II; Biopsy, Needle; Chronic Disease; Diagnosis, Differential; Epinephrine; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney; Kidney Function Tests; Norepinephrine; Pheochromocytoma; Radioisotope Renography; Renal Artery; Renin; Vanilmandelic Acid | 1974 |
Letter: Test for role of angiotensin in hypertension.
Topics: Alanine; Angiotensin II; Humans; Hypertension; Sarcosine | 1974 |
The renin system: Variations in man measured by radioimmunoassay or bioassay.
Topics: Angiotensin II; Animals; Antibody Specificity; Aorta; Biological Assay; Cross Reactions; Diet; Female; Humans; Hypertension; Hypertension, Renal; Iodine Radioisotopes; Kidney; Kinetics; Neomycin; Radioimmunoassay; Renal Artery; Renal Veins; Renin; Sodium; Vena Cava, Inferior | 1972 |
Pressor substances in the posthemodialysis dialysates of patients with toxemia of pregnancy.
Topics: Angiotensin II; Animals; Barbiturates; Biological Assay; Blood Pressure; Buffers; Chromatography, Ion Exchange; Chromatography, Paper; Colon; Female; Glomerulonephritis; Humans; Hypertension; Peptides; Pre-Eclampsia; Pregnancy; Renal Dialysis; Trypsin; Uterus; Vasoconstrictor Agents | 1974 |
[Etiology and pathogenesis of hypertension].
Topics: Angiotensin II; Blood Pressure; Blood Volume; Catecholamines; Chronic Disease; Environmental Health; Heart; Hemodynamics; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Pressoreceptors; Renal Artery Obstruction; Renin; Sodium | 1974 |
[The genesis of hyperuricemia in patients with essential hypertension (author's transl)].
Topics: Adult; Angiotensin II; Biological Transport; Blood Pressure; Body Weight; Creatinine; Electrolytes; Erythrocytes; Humans; Hypertension; Hypertension, Renal; Lactates; Nephritis; Sodium; Uric Acid | 1974 |
Cerebral blood flow in acute hypertension.
Topics: Anesthetics; Angiotensin II; Animals; Autoradiography; Blood Flow Velocity; Blood Pressure; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models, Animal; Hypertension; Methoxyflurane; Rabbits; Thiopental; Vasomotor System | 1974 |
The renin-angiotensin system (second of two parts).
Topics: Angiotensin II; Arteries; Extracellular Space; Female; Heart Failure; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Hypertension, Renal; Kidney Failure, Chronic; Kidney Neoplasms; Liver Diseases; Mineralocorticoids; Pre-Eclampsia; Pregnancy; Renin; Sodium; Wilms Tumor | 1974 |
A clinical test useful for predicting the development of acute hypertension in pregnancy.
Topics: Acute Disease; Angiotensin II; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Infusions, Parenteral; Methods; Posture; Pregnancy; Pregnancy Complications, Cardiovascular; Time Factors | 1974 |
Plasma angiotensin-like activity in hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin II; Biological Assay; Child; Child, Preschool; Female; Humans; Hypertension; Male; Middle Aged; Nephrectomy; Pregnancy; Renal Artery Obstruction | 1974 |
[Influence of angiotensin II-infusion on the sodium- and potassium level in plasma and erythrocytes of normotensive persons and patients with essential hypertension (author's transl)].
Topics: Adult; Angiotensin II; Cell Membrane Permeability; Erythrocytes; Humans; Hypertension; Infusions, Parenteral; Injections, Intravenous; Middle Aged; Potassium; Sodium | 1974 |
[Induced hypertension (stages 3 and IV) in patients with chronic peripheral arteriopathy (author's transl)].
Topics: Adult; Angiotensin II; Arterial Occlusive Diseases; Chronic Disease; Desoxycorticosterone; Humans; Hydrocortisone; Hypertension; Middle Aged; Mineralocorticoids; Pain; Regional Blood Flow; Rest; Steroids, Fluorinated; Sympathectomy; Varicose Ulcer | 1974 |
[Proceedings: Pathogenesis of hypertension--hypotheses and facts].
Topics: Angiotensin II; Animals; Humans; Hypertension; Rats; Renin; Sodium | 1974 |
[Prognosis of hypertension disease and of the system renin-angiotension-aldosteron (author's transl)].
Topics: Aldosterone; Angiotensin II; Arteries; Humans; Hydrocortisone; Hypertension; Prognosis; Radioimmunoassay; Renin; Veins | 1974 |
[Angiotensin test in the diagnosis of vasorenal hypertension].
Topics: Adrenal Gland Diseases; Angiotensin II; Humans; Hypertension; Hypertension, Renal; Kidney Function Tests; Nephritis; Renal Artery Obstruction | 1974 |
[Importance of formatio reticularis mesencephali in experimental models of hypertension].
Topics: Angiotensin II; Animals; Blood Circulation; Blood Pressure; Carotid Sinus; Disease Models, Animal; Electric Stimulation; Electrocoagulation; Electrodes, Implanted; Female; Hemodynamics; Hypertension; Male; Mesencephalon; Rabbits; Reticular Formation | 1974 |
[Intrarenal regulation of sodium excretion in hypertension].
Topics: Angiotensin II; Animals; Hypertension; Hypertension, Renal; Juxtaglomerular Apparatus; Metabolic Clearance Rate; Natriuresis; Rats; Renin; Sodium | 1974 |
Plasma aldosterone during haemodialysis in patients with terminal renal failure.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Blood Pressure; Body Weight; Humans; Hydrocortisone; Hypertension; Kidney Failure, Chronic; Potassium; Radioimmunoassay; Renal Dialysis; Renin; Sodium | 1973 |
Variable sensitivity of different hypertensives to constant infusion of angiotensin.
Topics: Adolescent; Adult; Aged; Angiotensin Amide; Angiotensin II; Diagnosis, Differential; Humans; Hypertension; Hypertension, Renal; Middle Aged | 1974 |
Increased activity of a factor ("transferangiotensin") favoring the binding of angiotensin II to arterial wall in hypertension.
Topics: Adult; Angiotensin II; Animals; Arteries; Blood Proteins; Calcium; Centrifugation; Chromatography, Gel; Chromatography, Ion Exchange; Dialysis; Drug Synergism; Edetic Acid; Electrophoresis; Heating; Humans; Hydrogen-Ion Concentration; Hypertension; Iodine Radioisotopes; Middle Aged; Pronase; Protein Binding; Rabbits; Sepharose; Spectrophotometry | 1974 |
Decreased response of plasma renin activity to orthostasis in diabetic patients with orthostatic hypotension.
Topics: Adult; Aldosterone; Amyloidosis; Angiotensin II; Animals; Blood Pressure; Cattle; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hypertension; Hypotension, Orthostatic; Iodine Radioisotopes; Male; Middle Aged; Norepinephrine; Posture; Pulse; Rabbits; Radioimmunoassay; Renin; Tyramine | 1974 |
Letter: Prostaglandins in renal venous blood of essential hypertensive patients.
Topics: Angiotensin II; Chromatography, Thin Layer; Humans; Hypertension; Pheochromocytoma; Prostaglandins; Renal Veins | 1974 |
[Exchangeable sodium and sodium space in some types of hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension; Renin; Sodium | 1974 |
Cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Age Factors; Angiotensin II; Animals; Cardiomegaly; DNA; Heart Ventricles; Hydralazine; Hypertension; Methyldopa; Organ Size; Rats; Rats, Inbred Strains; Renin | 1974 |
Clinical use of renin determinations.
Topics: Aldosterone; Angiotensin II; Blood Volume; Feedback; Humans; Hypertension; Hypertension, Renal; Methods; Posture; Potassium; Prognosis; Radioimmunoassay; Renal Dialysis; Renin; Sodium; Water | 1974 |
Plasma angiotensin II activity in essential hypertension. Relation with vascular complications.
Topics: Adult; Aged; Angiotensin II; Cerebrovascular Disorders; Coronary Disease; Female; Humans; Hypertension; Ischemia; Male; Middle Aged | 1974 |
Neurogenic and humoral factors controlling vascular resistance in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Barium; Biological Assay; Blood Pressure Determination; Chemoreceptor Cells; Epinephrine; Hexamethonium Compounds; Hindlimb; Hypertension; Norepinephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Sympathectomy; Tyramine; Vascular Resistance; Vasomotor System | 1974 |
Editorial: Angiotensin inhibition.
Topics: Alanine; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Humans; Hypertension; Hypertension, Renal; Oligopeptides; Renin; Sarcosine | 1974 |
The validity of comparing the measurements of angiotensin I generated in human plasma by radioimmunoassay and bioassay.
Topics: Angiotensin II; Animals; Biological Assay; Humans; Hypertension; Immune Sera; Iodine Radioisotopes; Rabbits; Radioimmunoassay; Rats; Regression Analysis; Renin | 1974 |
Simplified radioimmunoassay of angiotensin II.
Topics: Adult; Aged; Angiotensin II; Antibody Formation; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Malignant; Immune Sera; Male; Middle Aged; Radioimmunoassay; Renin | 1974 |
Vascular reactivity in spontaneously hypertensive normotensive and hypotensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Heart; Hemodynamics; Hypertension; Hypotension; Norepinephrine; Organ Size; Rats; Rats, Inbred Strains; Vagotomy | 1974 |
Renin and hypertension.
Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Prognosis; Renin | 1973 |
Hypertension: selection of treatment in relation to the mechanisms raising blood pressure.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Diuretics; Humans; Hyperaldosteronism; Hypertension; Neoplasms; Propranolol; Renin; Sodium; Sympathetic Nervous System | 1973 |
Characteristics of hypertension in the black population.
Topics: Adult; Angiotensin II; Animals; Black or African American; Cardiomegaly; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Guanethidine; Heart Ventricles; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; New York City; Rabbits; Radioimmunoassay; Renin; Sodium; Spironolactone | 1974 |
Adolescent hypertension. II. Characteristics and response to treatment.
Topics: Adolescent; Adult; Angiotensin II; Black or African American; Female; Humans; Hydralazine; Hypertension; Kidney; Latin America; Male; Mass Screening; Methyldopa; New York City; Propranolol; Radioimmunoassay; Renin; Sodium; Spironolactone | 1974 |
[The effect of oral contraceptives on plasma renin activity and plasma renin substrate concentration (author's transl)].
Topics: Adult; Aldosterone; Angiotensin II; Contraceptives, Oral; Drug Combinations; Ethinyl Estradiol; Feedback; Female; Humans; Hypertension; Liver; Lynestrenol; Megestrol; Norethindrone; Norgestrel; Radioimmunoassay; Renin; Stimulation, Chemical; Time Factors | 1974 |
The relation of plasma renin activity to left ventricular hypertrophy and retinopathy in patients with arterial hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin II; Cardiomegaly; Heart Ventricles; Humans; Hyperaldosteronism; Hypertension; Kidney Diseases; Middle Aged; Radioimmunoassay; Renin; Retinal Diseases; Sodium Chloride | 1974 |
Differential effects of propranolol on heart rate and plasma renin activity in patients treated with minoxidil.
Topics: Adult; Aged; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Creatinine; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Minoxidil; Perfusion; Propranolol; Radioimmunoassay; Regional Blood Flow; Renin; Sodium; Time Factors; Vasodilator Agents | 1974 |
[Therapeutic progress in the area of arterial hypertension].
Topics: Adult; Angiotensin II; Antihypertensive Agents; Arteriosclerosis; Belgium; Catecholamines; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; Prognosis; Renin; Sympathetic Nervous System | 1974 |
[Evidence for circadian variability in the renin-angiotensin II system (author's transl)].
Topics: Adult; Angiotensin II; Circadian Rhythm; Humans; Hypertension; Male; Radioimmunoassay; Renin | 1974 |
Clinical applications of synthetic angiotensin II analogue.
Topics: Adult; Aged; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Injections, Intravenous; Male; Mice; Middle Aged; Radioimmunoassay; Rats | 1974 |
Pressor responsiveness, hemodynamics and plasma renin activity in essential hypertension.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Cardiac Output; Dye Dilution Technique; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Rest; Sodium; Tyramine; Vascular Resistance | 1974 |
Effects of angiotensin on catecholamine metabolism in rat.
Topics: Adrenal Medulla; Angiotensin II; Animals; Calcium; Corpus Striatum; Dopamine; Epinephrine; Hypertension; Hypothalamus; Magnesium; Monoamine Oxidase; Norepinephrine; Perfusion; Potassium; Rats | 1974 |
Analysis of relationship between renin-angiotensin system and blood pressure in experimental hypertension induced by kidney extract.
Topics: Adrenalectomy; Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Kidney; Male; Nephrectomy; Plethysmography; Radioimmunoassay; Rats; Renin; Tissue Extracts | 1974 |
The kidney factors in the production of acute hypertensive vascular lesions.
Topics: Acute Disease; Angiotensin II; Animals; Arteries; Edema; Female; Fluorescent Antibody Technique; Hypertension; Injections; Kidney Cortex; Lysosomes; Mitochondria; Necrosis; Nephrectomy; Pancreas; Pleural Effusion; Rabbits; Rats; Renin; Solubility; Subcellular Fractions; Tissue Extracts; Vascular Diseases | 1974 |
[Antihypertensive drugs].
Topics: Angiotensin II; Antihypertensive Agents; Diuretics; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Monoamine Oxidase Inhibitors; Norepinephrine; Prostaglandins; Renin; Sympatholytics; Vasodilator Agents | 1974 |
Some observations on arterial and venous levels of angiotensin II in man.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Creatinine; Female; Humans; Hypertension; Iodine Radioisotopes; Male; Middle Aged; Radioimmunoassay; Renin; Sodium | 1974 |
The prevalence of hypertension in an unselected population, and the frequency of abnormalities of potassium, angiotensin II and aldosterone in hypertensive subjects.
Topics: Aldosterone; Angiotensin II; Female; Health Surveys; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Potassium; Scotland | 1974 |
Borderline hypertension: correlation between the cardiac output and the vascular reactivity to norepinephrine.
Topics: Adult; Angiotensin II; Cardiac Output; Heart Rate; Humans; Hypertension; Isoproterenol; Male; Norepinephrine; Vascular Resistance | 1974 |
Blood vessel wall characteristics in experimental hypertension.
Topics: Angiotensin II; Animals; Aorta; Cadmium; Carotid Arteries; Dogs; Elasticity; Hypertension; Injections, Intraperitoneal; Muscle, Smooth; Norepinephrine; Rabbits; Renal Artery; Serotonin; Vasomotor System | 1974 |
[Angiotensin blockade and hypertension].
Topics: Alanine; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Humans; Hypertension; Sarcosine | 1974 |
The permeability pathways in the walls of intesinal submucosal arterioles in acute angiotensin-induced hypertension in rats.
Topics: Angiotensin II; Animals; Basement Membrane; Capillary Permeability; Carbon; Colloids; Cytoplasm; Endothelium; Hypertension; Intercellular Junctions; Intestinal Mucosa; Jejunum; Male; Microcirculation; Microscopy, Electron; Muscle, Smooth; Neutrophils; Rats; Vacuoles | 1974 |
Ultrastructural pathological changes in intestinal submucosal arterioles in angiotensin-induced acute hypertension in rats.
Topics: Angiotensin II; Animals; Capillary Permeability; Carbon; Cytoplasm; Cytoplasmic Granules; Endothelium; Hypertension; Intestinal Mucosa; Microcirculation; Microscopy, Electron; Mitochondria; Muscle, Smooth; Neutrophils; Rats; Vacuoles | 1974 |
[Experimental perspectives on the pathogenesis of essential arterial hypertension].
Topics: Aldosterone; Angiotensin II; Animals; Anxiety; Blood Coagulation; Epinephrine; Fibrinolysis; Heart Rate; Hemodynamics; Humans; Hypertension; Norepinephrine; Osmotic Pressure; Rats; Renin; Stress, Physiological; Vascular Resistance | 1974 |
[Changes in local perivascular H+ and K+ activities in the pia mater vessels in the cat in experimental hypotension].
Topics: Acidosis; Angiotensin II; Animals; Cats; Hydrogen-Ion Concentration; Hypertension; Meningeal Arteries; Norepinephrine; Pia Mater; Potassium | 1974 |
[Proceedings: Plasma aldosterone response to angiotensin injection in essential hypertension and various other diseases].
Topics: Aldosterone; Angiotensin II; Humans; Hypertension | 1974 |
[Proceedings: Study on participation of renin-angiotensin system in various types of hypertension by clinical application of an angiotensin II analogue (1-sar, 8-Ile-angiotensin II)].
Topics: Angiotensin II; Humans; Hypertension; Renin | 1974 |
[Proceedings: Changes in renin-angiotensin system in essential hypertension and thyroid diseases].
Topics: Angiotensin II; Humans; Hypertension; Renin; Thyroid Diseases | 1974 |
Proceedings: Angiotensin II levels in normal and hypertensive primigravid pregnancy.
Topics: Angiotensin II; Blood Pressure; Edema; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Proteinuria | 1974 |
The relationship between the plasma concentrations of renin and angiotensin with total exchangeable sodium in hypertension.
Topics: Angiotensin II; Child; Female; Humans; Hypertension; Renin; Sodium | 1974 |
[Pathogenesis of hypertension--hypotheses and facts].
Topics: Angiotensin II; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Renin | 1974 |
[Renin and sodium in blood pressure regulation].
Topics: Angiotensin II; Animals; Antibodies; Blood Pressure; Blood Volume; Disease Models, Animal; Homeostasis; Humans; Hypertension; Hypertension, Renal; Kidney; Renin; Sodium | 1974 |
Estimation of urinary angiotensin II by radioimmunoassay.
Topics: Angiotensin II; Cushing Syndrome; Glomerulonephritis; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Radioimmunoassay; Renal Artery Obstruction | 1974 |
Renomedullary endocrine system: its antihypertensive action.
Topics: Angiotensin II; Animals; Connective Tissue; Connective Tissue Cells; Culture Techniques; Hormones; Hypertension; Kidney; Kidney Medulla; Nephrectomy; Rats; Sodium; Time Factors; Transplantation, Homologous | 1974 |
[Hemodynamic regulation of the heart in hypertension under intravenous administration of dihydralazine].
Topics: Angiotensin II; Blood Pressure; Heart; Heart Rate; Hemodynamics; Humans; Hydralazine; Hypertension; Injections, Intravenous; Kinins; Renin | 1974 |
[Studies on the nature and origin of the hypertensive principles present in the placenta, uterus and liver].
Topics: Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Kidney Cortex; Liver; Placenta; Pregnancy; Proteins; Rabbits; Rats; Renin; Swine; Uterus | 1974 |
[3. Transferoangiotensin in arterial hypertension. Electrophoretic motility and identification of binding compounds].
Topics: Angiotensin II; Blood Protein Electrophoresis; Blood Proteins; Chromatography, Paper; Humans; Hypertension | 1974 |
[Arterial hypertension (author's transl)].
Topics: Aldosterone; Angiotensin II; Epinephrine; Humans; Hypertension; Mineralocorticoids; Norepinephrine; Renin | 1974 |
[Chemistry and mechanism of new angiotensin UU antagonists: 8 C-phenylclycine analogues of [5-isoleucine] angiotensin].
Topics: Angiotensin II; Animals; Blood Pressure; Hypertension; Hypertension, Renal; In Vitro Techniques; Isoleucine; Muscle Contraction; Muscle, Smooth; Rats; Structure-Activity Relationship | 1974 |
Vascular reactivity to angiotensin in borderline hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Cardiac Output; Heart Rate; Humans; Hypertension; Male; Renin; Sympathetic Nervous System; Vasomotor System | 1974 |
[Dynamic aspects of the renin-plasma activity in subjects affected by essential arterial hypertension].
Topics: Adult; Angiotensin II; Humans; Hypertension; Male; Renin | 1974 |
The renin-angiotensin system in diabetes mellitus.
Topics: Angiotensin II; Blood Pressure; Diabetes Mellitus; Epinephrine; Furosemide; Humans; Hypertension; Juxtaglomerular Apparatus; Norepinephrine; Renin; Stimulation, Chemical | 1974 |
Central hypertensive actions of angiotensin.
Topics: Angiotensin II; Animals; Blood Pressure; Cats; Cerebral Ventricles; Drug Synergism; Hypertension; Injections, Intraventricular; Oligopeptides; Phentolamine; Saralasin; Stimulation, Chemical; Teprotide | 1974 |
Plasma renin activity in hemodialysis patients: a longitudinal study.
Topics: Acute Kidney Injury; Adult; Aged; Angiotensin II; Blood Pressure; Body Weight; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Renin; Ultrafiltration | 1974 |
Renin-aldosterone axis in renal transplant patients.
Topics: Adult; Aldosterone; Angiotensin II; Female; Graft Rejection; Humans; Hypertension; Hypertension, Malignant; Ischemia; Kidney Transplantation; Male; Middle Aged; Potassium; Prednisone; Renal Artery Obstruction; Renal Dialysis; Renin; Sodium; Transplantation, Homologous | 1974 |
Cardiovascular reactivity in acute and chronic renal hypertensive dogs.
Topics: Acute Disease; Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Chronic Disease; Dogs; Hindlimb; Hypertension; Hypertension, Renal; Reference Values; Vasoconstriction | 1966 |
Absence of direct chronotropic action of angiotensin infused into the sinus node artery.
Topics: Angiotensin II; Animals; Dogs; Electrocardiography; Ethanolamines; Heart Conduction System; Hypertension; Norepinephrine; Reflex; Sinoatrial Node; Tachycardia; Vagus Nerve | 1965 |
The effect of pregnancy on the central sympathetic components in angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Cats; Female; Hypertension; Lactation; Pregnancy; Pregnancy, Animal | 1966 |
Hypertension and neuro-humoral substances.
Topics: Angiotensin II; Humans; Hypertension; Neurotransmitter Agents | 1968 |
The effect of ganglionic blockade on the pressor response to angiotensin in systemic hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Blood Volume; Ganglionic Blockers; Humans; Hypertension; Middle Aged; Stimulation, Chemical; Vascular Resistance | 1969 |
Cardiovascular reactivity in the experimental hypertensive rat.
Topics: Angiotensin II; Animals; Blood Pressure; Cordotomy; Corticosterone; Electric Stimulation; Ganglionic Blockers; Hypertension; Hypertension, Renal; Male; Mesentery; Norepinephrine; Piperazines; Rats; Sodium Chloride; Sympathetic Nervous System; Tyramine | 1971 |