angiotensin ii has been researched along with Disease Models, Animal in 2232 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 114 (5.11) | 18.7374 |
| 1990's | 142 (6.36) | 18.2507 |
| 2000's | 537 (24.06) | 29.6817 |
| 2010's | 1137 (50.94) | 24.3611 |
| 2020's | 302 (13.53) | 2.80 |
| Authors | Studies |
|---|---|
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Ali, F; Cheng, Y; Chu, J; Fang, Y; Liu, H; Peng, J; Shen, A; Wang, D; Wei, L; Wu, M; Xie, Q; Yan, M; Yang, Y | 1 |
| Liu, A; Shang, Z; Zhang, Y | 1 |
| Cheng, C; Cheng, J; Hao, P; Sui, W; Wang, X; Xing, Y; Xue, F; Zhang, C; Zhang, J; Zhang, M; Zhang, Y | 1 |
| Billoff, S; Bode-Böger, SM; Bornstein, SR; Deussen, A; Jarzebska, N; Kolouschek, A; Kopaliani, I; Mangoni, AA; Martens-Lobenhoffer, J; Ragavan, VN; Rodionov, RN; Weiss, N | 1 |
| Chang, YM; Chen, RJ; Chiu, PL; Day, CH; Huang, CY; Huang, HY; Kuo, WW; Liang-Yo, Y; Lin, HJ; Mahendran, R; Padma, VV | 1 |
| Chang, TT; Chen, JW; Liao, LY | 1 |
| Chen, W; Cong, C; Hu, Y; Tao, L; Wang, Y; Yuan, X | 1 |
| Brines, M; Chavan, SS; Li, JH; Shah, V; Stiegler, A; Tamari, Y; Tracey, KJ; Tsaava, T; Tynan, A; Yang, H | 1 |
| Alvarado-Ojeda, ZA; Arrellín-Rosas, G; Castro-Martínez, G; Cervantes-Torres, J; Costet-Mejía, A; Fragoso, G; Hernández-Téllez, B; Herrera-Ruiz, M; Jiménez-Ferrer, E; Medina-Campos, ON; Méndez-Martínez, M; Pedraza-Chaverri, J; Ramírez-Pliego, O; Rosas-Salgado, G; Santana, MA; Trejo-Moreno, C | 1 |
| Agic, MB; Kunath, A; Mani, K; Näsström, M; Petri, MH; Ramilo, AB; Wågsäter, D; Wanhainen, A | 1 |
| Cai, X; Deng, L; Fan, G; Guo, R; Li, L; Liu, W; Ni, J; Xu, Q; Zhang, D; Zhao, Y | 1 |
| Bian, H; Cho, K; Han, N; Jiang, B; Li, X; Wang, L; Wang, Y; Wu, P; Yin, J; Zhang, X; Zhang, Y | 1 |
| Chen, L; Geng, Q; Jiang, W; Li, N; Wang, B; Wang, W; Xiong, R | 1 |
| Chen, H; Chen, YX; Deng, TT; Zhao, XY | 1 |
| An, J; Asaka, MN; Chan, CC; Chan, JF; Fujino, Y; Hoshizaki, M; Imai, M; Imai, Y; Kamada, H; Kamitani, W; Kawaoka, Y; Kiso, M; Kuba, K; Maeda, K; Minato, T; Motoyama, S; Nagata, S; Niiyama, M; Nirasawa, S; Nukiwa, R; Penninger, JM; Poon, VK; Saku, A; Takahashi, S; Uda, A; Utsumi, D; Yamaguchi, T; Yasuhara, A; Yasutomi, Y; Yuen, KY | 1 |
| Alenina, N; Bader, M; Clahsen-van Groningen, MC; Danser, AHJ; Essers, J; Garrelds, IM; Qadri, F; Ridwan, Y; Roks, AJM; van der Linden, J; van der Pluijm, I; van Thiel, BS; Vermeij, M | 1 |
| Bilen, A; Celik, M; Celik, Z; Gulaboglu, M; Halici, Z; Kul, A; Kutlu, Z; Maman, A | 1 |
| Araújo Júnior, RF; Araújo, AA; Bader, M; Barbosa, SJA; Brito, GAC; Guerra, GCB; Leitão, RFC; Lima, MLS; Martins, AA; Medeiros, CACX; Melo, RCO; Pirih, FQ; Santos, R; Silva, RA | 1 |
| Carletti, R; Castoldi, G; di Gioia, CRT; Ippolito, S; Pelucchi, S; Stella, A; Zatti, G; Zerbini, G | 1 |
| Dai, H; Jia, G; Li, W; Liang, C | 1 |
| Ageedi, W; Coselli, JS; Dawson, A; Frankel, WC; LeMaire, SA; Li, Y; Shen, HY; Zhang, C | 1 |
| Beltz, TG; Guo, F; Johnson, AK; Wei, SG; Xue, B; Yu, Y | 1 |
| Chen, X; Liu, X; Lou, J; Tang, L; Weng, Y; Xu, C | 1 |
| Cao, Y; Chen, C; Chen, Y; Deng, K; Deng, X; Han, X; He, C; He, J; Jiang, W; Lei, A; Li, X; Liu, G; Lu, L; Tan, M; Wang, Y; Wu, P; Xiao, Q; Xu, H; Yang, Q; Yao, Z; Zhang, L; Zhou, J; Zhou, P | 1 |
| Cassis, LA; Daugherty, A; Lu (吕红), HS; Sawada (澤田悠), H | 1 |
| Chen, D; Cheng, Y; Gong, Y; Han, W; Liu, Z; Song, B; Zhang, R; Zhang, Z | 1 |
| Feng, Y; Geng, C; Li, Z; Tang, Y; Wang, J; Yang, H; Yang, Y; Zhao, H | 1 |
| Ali, BH; Beegam, S; Elzaki, O; Ferdous, Z; Greish, YE; Nemmar, A; Tariq, S; Zaaba, NE | 1 |
| Antunes, E; Baldanzi, G; Billis, A; Brito, PL; Chweih, H; Conran, N; Costa, FF; de Oliveira, MG; Dos Santos, AF; Favero, ME; Ferreira, WA; Franco-Penteado, CF; Gotardo, EMF; Leonardo, FC; Mashima, DA; Saad, STO; Silva, JAF; Zaidan, BC | 1 |
| Assi, R; Caulk, AW; He, C; Humphrey, JD; Jiang, B; Li, G; Lovoulos, CJ; Murtada, SI; Qin, L; Ren, P; Schwartz, MA; Tellides, G; Wang, M | 1 |
| Bajo, MA; Briones, AM; Cannata-Ortiz, P; Egido, J; Esteban, V; Falke, LL; Goldschmeding, R; Mallat, Z; Orejudo, M; Ortiz, A; Rayego-Mateos, S; Rodrigues-Díez, R; Rodrigues-Díez, RR; Ruiz-Ortega, M; Steffensen, LB; Tejera-Muñoz, A | 1 |
| Chen, H; Guo, M; Hu, J; Peng, N; Qi, Y; Shen, S; Sun, X; Xu, B; Xu, J; Zhang, Q; Zhang, W; Zhang, Y | 1 |
| Aikawa, M; Chen, JZ; Daugherty, A; Franklin, MK; Higashi, H; Howatt, DA; Katsumata, Y; Lee, LH; LeMaire, SA; Li, Y; Lu, HS; Majesky, MW; Moorleghen, JJ; Morgan, S; Rateri, DL; Sawada, H; Shen, YH; Singh, SA; Zhang, C | 1 |
| Afanasiev, SA; Blanco, P; Burger, D; Burns, KD; Correa, JWN; Gutsol, AA; Hale, TM; Hébert, RL; Holterman, CE; Kennedy, CRJ; Nasrallah, R; Thibodeau, JF; Touyz, RM | 1 |
| Chang, WH; Lu, HY; Shih, CC; Wu, TC | 1 |
| Calus, E; De Deyn, PP; De Meyer, GRY; Hendrickx, JO; Van Dam, D | 1 |
| Cassis, LA; de Beer, FC; Dugan, AJ; Ji, A; Leung, SW; Noffsinger, VP; Shridas, P; Tannock, LR; Thatcher, SE; Trumbauer, AC; Webb, NR | 1 |
| Huh, J; Jeon, SJ; Jeong, E; Park, CK; Park, HYL | 1 |
| Asada, Y; Chosa, E; Funamoto, T; Hatakeyama, K; Kato, J; Kitamura, K; Koide, M; Nakamichi, Y; Otsu, M; Sekita-Hatakeyama, Y; Tsuruda, T; Udagawa, N; Yamashita, A | 1 |
| Ao-Ieong, WS; Chen, CH; Ho, HH; Jiang, WC; Layne, MD; Orekhov, AN; Sobenin, IA; Wang, J; Yet, SF | 1 |
| Chacar, S; Fares, N; Hajal, J; Jreije, A; Khouzami, L; Medlej-Hashim, M; Saliba, Y | 1 |
| Bao, Y; Cai, C; Chen, X; Du, C; Lou, J; Tang, L; Weng, Y; Zhu, K | 1 |
| Du, J; Kong, L; Li, Y; Yang, C; Yao, R; Zhao, G | 1 |
| Ge, X; Lu, Y; Meng, L; Meng, X; Sui, W; Wang, X; Zhang, Y; Zhong, M | 1 |
| Chen, L; Liang, Q; Liu, M; Qian, L; Xu, H; Yan, J; Yang, G | 1 |
| Chao de la Barca, JM; Eid, M; Fassot, C; Faure, J; Fouquet, O; Henrion, D; Loufrani, L; Reynier, P; Richard, A; Robert, P; Tessier, L; Wetterwald, C | 1 |
| Gao, Y; Guo, X; Hu, L; Li, Y; Liu, Y; Ma, S; Tang, J; Wang, Z; Wei, J; Zhang, Q; Zhang, X; Zhang, Y | 1 |
| Ding, S; Feng, ZH; Geng, N; Guo, X; Huang, L; Lin, GQ; Lin, N; Lyu, YY; Pu, J; Qian, K; Shen, Z; Sun, LY; Wang, YL; Yuan, AC; Zhang, HY; Zhang, L | 1 |
| Almeida-Santos, AF; Colpo, GD; Furr Stimming, E; Guatimosim, C; Joviano-Santos, JV; Kangussu, LM; Latham, LB; Machado, TCG; Miranda, AS; Rocha, NP; Simões E Silva, AC; Soares, KB; Teixeira, AL; Valadão, PAC | 1 |
| Cooper, STE; Haines, ZHR; Malone, GO; Meijles, DN; Sheppard, MN; Westaby, JD | 1 |
| Chang, WT; Chen, CL; Chen, ZC; Chu, JS; Huang, TL; Lin, YW; Liu, PY; Shih, JY | 1 |
| Boekell, KL; Brown, BJ; Schlondorff, JS; Stotter, BR; Talbot, BE | 1 |
| Betazza, MC; Cianciulli, TF; Fontana Estevez, FS; Gironacci, M; González, GE; Goren, N; Medina, V; Miksztowicz, V; Morales, C; Penas, F; Selser, C; Seropian, IM; Silva, MG; Touceda, V; Villaverde, A | 1 |
| Abu Bakar, ZH; Hamezah, HS; Matsuzaki Tada, A; Pahrudin Arrozi, A; Tooyama, I; Yanagisawa, D | 1 |
| Han, P; Jensen, DM; Kriegel, AJ; Liang, M; Liu, J; Lopez-Berestein, G; Mangala, LS; Sood, AK; Usa, K; Widlansky, ME | 1 |
| Abraham, MN; Bellomo, R; Brewer, MR; Capone, CC; Crowley, SD; Deutschman, CS; Fernandes, TD; Goldberg, MB; Griffiths, R; Lehman, JR; Leisman, DE; Nedeljkovic-Kurepa, A; Privratsky, JR; Stein, WJ; Taylor, MD; Yaipan, OY | 1 |
| Bailey, MA; Bleichert, S; Brostjan, C; Busch, A; Eilenberg, W; Ibrahim, N; Klopf, J; Neumayer, C; Stiglbauer-Tscholakoff, A | 1 |
| Daugherty, A; Franklin, MK; Howatt, DA; Lu, HS; Moorleghen, JJ; Mullick, AE; Ohno-Urabe, S; Sawada, H; Ye, D | 1 |
| Chang, L; Chang, Z; Chen, YE; Garcia-Barrio, MT; Guo, Y; Liang, W; Lin, JD; Liu, H; Liu, Y; Lu, H; Rom, O; Wang, H; Yang, B; Zhang, J; Zhao, G; Zhao, Y; Zhu, T | 1 |
| Dohgu, S; Inada, K; Koga, M; Yamada, A; Yamauchi, A | 1 |
| Annoni, F; Creteur, J; Dewachter, L; Favory, R; Garcia, B; Herpain, A; Hubesch, G; Khaldi, A; Moiroux-Sahraoui, A; Njimi, H; Rocha-Oliveira, E; Roncon-Albuquerque, R; Su, F; Taccone, FS; Vasques-Nóvoa, F; Vincent, JL | 1 |
| Barthelemy, J; Bogard, G; Briand, F; Chabrat, A; Deruyter, L; Domenig, O; Heumel, S; Hoffmann, E; Infanti, F; Machelart, A; Nogueiras, R; Pinet, F; Prévot, V; Richard, V; Robil, C; Sencio, V; Sulpice, T; Trottein, F; Wolowczuk, I | 1 |
| Gong, K; Guo, S; Li, R; Li, Y; Qiu, C; Xiao, L; Zhao, Y | 1 |
| Chai, H; Chen, W; Chen, X; Fan, R; Hu, Y; Huang, F; Jiang, H; Liu, R; Zhou, Y | 1 |
| Chen, D; Gao, S; Ge, S; Luo, J; Niu, K; Ren, M; Shao, Y; Wang, X; Wu, Q; Xiao, Q; Yang, M; Yang, Z; Zhang, C; Zhou, X | 1 |
| Darmon, A; Dupont, S; El Bitar, S; Jondeau, G; Michel, JB; Pellenc, Q | 1 |
| Aono, J; Hamaguchi, M; Ikeda, S; Inoue, K; Kakino, A; Kurata, M; Nakao, Y; Sakaue, T; Sawamura, T; Suehiro, C; Suzuki, J; Takahashi, K; Yamaguchi, O | 1 |
| Cai, H; Huang, K; Wu, Y; Youn, JY; Zhang, Y | 1 |
| Ballasy, NN; Belke, D; Fedak, PWM; Gomes, KP; Jadli, AS; Mackay, CDA; Meechem, M; Patel, VB; Thompson, J; Wijesuriya, TM | 1 |
| Cai, D; Chen, SY; Murashita, T; Que, X; Sun, C | 1 |
| Ayares, D; Bikhet, MH; Cooper, DKC; Hansen-Estruch, C; Javed, M; Judd, E; Katsurada, A; Navar, LG; Satou, R; Shao, W; Venkataramanan, R | 1 |
| Ashida, S; Mutsuga, M; Narita, Y; Tokoro, M; Usui, A; Yamawaki-Ogata, A | 1 |
| Furuyama, T; Hoshino, T; Kurose, S; Matsubara, Y; Morisaki, K; Yoshino, S; Yoshiya, K; Yoshizumi, T | 1 |
| Huang, PH; Lin, SJ; Tsai, HY; Tsai, SH; Wang, JC | 1 |
| Cicalese, SM; Eguchi, S; Hashimoto, T; Okuno, K; Rizzo, V; Sparks, MA; Torimoto, K | 1 |
| Ding, Q; Du, Y; Li, H; Ma, T; Meng, Q; Sun, D; Zhang, X; Zhang, Z; Zheng, H; Zhuang, J | 1 |
| Almendra-Pegueros, R; Consegal-Pérez, M; Galán, M; Jiménez-Altayó, F; Julve, J; Kassan, M; Martínez-González, J; Navas-Madroñal, M; Pérez, B; Puertas-Umbert, L; Rodriguez, C | 1 |
| Bai, X; Meng, Z; Su, Y; Wang, Y; Xu, L; Yang, X; Zhuo, C | 1 |
| Cao, Y; Chai, H; Chen, G; Chen, W; Chen, X; Fan, R; Jiang, H; Liu, Y; Qin, W; Qiu, Z; Wang, X; Xu, Y; Yao, Y | 1 |
| Guo, R; Li, Y; Tao, L; Xu, Y | 1 |
| Gao, L; Jia, M; Wang, Z; Wu, L; Xiao, L; Yao, R; Zhang, Y | 1 |
| Chen, CY; Chen, JS; Chen, JW; Huang, PH; Lin, CP; Lin, SJ; Tzeng, IS; Wu, MY | 1 |
| Kokkonen-Simon, K; Kovacs, A; Li, T; Matkovich, SJ; Matsiukevich, D; Oladipupo, SS; Ornitz, DM | 1 |
| Bai, H; Ben, J; Chen, Q; Huang, J; Ji, R; Jia, Y; Jiang, B; Jiang, Y; Li, X; Wang, J; Wang, S; Yang, Q; Zhang, H; Zhou, Z; Zhu, X | 1 |
| Chen, D; Du, Y; Du, Z; Hu, C; Jiao, X; Li, F; Li, L; Lv, Q; Qin, Y; Sun, Q; Wang, Y; Yang, Y; Yu, H; Zhang, J; Zhang, X | 1 |
| Cai, Q; Davis, FM; Gallagher, KA; Gudjonsson, JE; Henke, PK; Joshi, AD; Mangum, K; Melvin, WJ; Tsoi, LC | 1 |
| Ge, Y; Guo, J; Ikezoe, T; Li, Z; Qin, M; Shi, J; Shoji, T; Wang, Y; Xu, B | 1 |
| Chen, Y; Lei, C; Li, F; Liu, B; Lv, Y; Song, W; Wu, J; Wu, X; Xie, T; Zheng, Y | 1 |
| Chen, X; Fang, X; Jiang, J; Lau, H; Liu, X; Pryke, L; Tang, L; Vyas, P; Xu, B; Xu, C; Yao, L; Yu, L | 1 |
| Adam, M; Ahdab, M; Baldus, S; Geißen, S; Guthoff, H; Hof, A; Landerer, M; Mehrkens, D; Mollenhauer, M; Niehues, J; Schäkel, J; Schorscher, M; von Stein, P; Winkels, H; Zimmermann, O | 1 |
| Ballasy, NN; Belke, D; Fedak, PWM; Gomes, KP; Jadli, AS; Patel, VB; Wijesuriya, TM | 1 |
| Kaga, S; Mori, K; Nakajima, H; Nakamura, S; Ogawa, Y; Okuma, H; Tsuchiya, K; Uchinuma, H | 1 |
| Alramahi, A; Berzins, SP; Fang, Y; Golledge, J; Magliano, DJ; Nguyen, DT; Oqueli, E; Parker, K; Pyke, SJR; Sargisson, O; Thihlum, L; Wallace, ME; Wang, Y | 1 |
| Alsac, JM; Arock, M; Caligiuri, G; Castier, Y; Clément, M; Coscas, R; Delbosc, S; Deschamps, L; Deschildre, C; Eggel, A; Even, G; Gaston, AT; Gautier, G; Guedj, K; Launay, P; Le Borgne, M; Loste, A; Louedec, L; Michel, JB; Morvan, M; Nicoletti, A; Procopio, E; Sénémaud, J | 1 |
| Cao, W; Chen, L; Fang, G; Gu, Y; Li, Y; Liu, L; Mo, B; Song, S; Wan, Y; Wang, Q; Wang, Y; Yu, Y; Zhang, R | 1 |
| Aubdool, A; Baliga, RS; Bedi, KC; D'Amico, G; Dukinfield, M; Hobbs, A; Hodivala-Dilke, K; Maiques, O; Maniati, E; Margulies, KB; Reynolds, LE; Sanz-Moreno, V; Wang, J | 1 |
| Cai, L; Hui, X; Li, S; Li, X; Liu, J; Liu, X; Shu, S; Wang, F; Xia, H; Yang, Y | 1 |
| Balasubbramanian, D; Gelston, CAL; Holderness, H; Iskander, G; Lopez, AH; Mitchell, BM; Rutkowski, JM; Tate, W | 1 |
| Gómez, GI; Sáez, JC; Velarde, V | 1 |
| Cao, M; Chen, X; Ding, J; Liao, M; Liao, Y; Qiu, Z; Wang, M; Wang, Y; Wu, H; Yan, X; Zhang, H; Zheng, J; Zhou, Y | 1 |
| Dev, R; Dhakal, P; Guerau-de-Arellano, M; Hans, CP; Kuivaniemi, H; Partida-Sanchez, S; Ruiz-Rosado, JD; Sharma, N | 1 |
| Boylston, J; Casin, KM; Fillmore, N; Kohr, MJ; Liu, C; Ma, H; Murphy, E; Noguchi, A; Sinha, P; Sun, J; Wang, N; Zhou, G | 1 |
| Gao, H; Lazartigues, E; Mukerjee, S; Sato, R; Xu, J; Zsombok, A | 1 |
| Asirvatham-Jeyaraj, N; Burnett, R; Fink, GD; Jones, AD | 1 |
| Dou, L; Guo, J; Huang, X; Li, J; Man, Y; Shen, T; Tang, W; Wang, Q; Wang, S; Yan, M; Yu, X; Zhu, K | 1 |
| Chen, X; Hu, X; Ke, F; Liao, Y; Qiu, Z; Wang, G; Wang, M; Wang, Y; Wu, H; Yan, X; Zhang, H; Zou, A | 1 |
| Bai, J; Guo, SB; Li, HH; Li, J; Li, JM; Lin, QY; Wang, S; Wang, T; Zhang, YL; Zhao, Q | 1 |
| Chiasson, V; Guleria, RS; Gupta, S; Takano, APC | 1 |
| Jiang, C; Kong, W; Li, X; Lian, G; Liu, H; Pang, Y; Sun, L; Wang, X; Zhang, L; Zhang, T; Zhang, X; Zhang, Y | 1 |
| Haibara, AS; Katsurada, K; Liu, X; Patel, KP; Sharma, NM | 1 |
| Cheng, C; Cheng, J; Li, H; Lu, L; Ma, J; Sui, W; Xu, J; Xu, X; Xue, F; Yang, J; Zhang, C; Zhang, J; Zhang, M; Zhang, Y | 1 |
| Hamel, E; Martinot, P; Royea, J | 1 |
| Denys, I; Gao, J; Kapusta, DR; Shahien, A; Sutphen, J | 1 |
| Deng, F; Fang, S; Zhang, B; Zhang, Y | 1 |
| Aghayev, T; Eguchi, S; Fatkhullina, AR; Gankovskaya, LV; Khoreva, MV; Koltsova, EK; Kossenkov, AV; Makhov, P; Peshkova, IO; Sykes, SM; Tan, YF; Titerina, EK | 1 |
| Ailawadi, G; Cullen, JM; Fashandi, AZ; Hawkins, RB; Lu, G; Mast, A; Montgomery, W; Salmon, M; Sharma, AK; Spinosa, M; Su, G; Upchurch, GR | 1 |
| Agarwal, G; Ahmadieh, S; Benjamin, S; Benson, TW; Blomkalns, AL; Edgell, A; Fulton, DJ; Gilreath, N; Horimatsu, T; Huo, Y; Kim, D; Kim, HW; Mann, A; Moses, M; Offermanns, S; Ogbi, M; Patel, S; Pye, J; Reid, L; Robbins, N; Singh, N; Stansfield, BK; Thompson, A; Weintraub, NL | 1 |
| Beer Stolz, D; Cerqueira, DM; Fu, H; Ho, J; Li, Y; Liu, Y; Rush, BM; Tan, RJ; Zhou, D | 1 |
| Che, Y; Jin, YG; Meng, YY; Shen, D; Wang, SS; Wang, ZP; Wu, QQ; Yuan, Y; Zhou, H | 1 |
| Fang, ZQ; Huo, YL; Johnson, AK; Li, JD; Peng, W; Wang, HP; Wang, XF; Xue, B; Zhang, YP | 2 |
| Gong, X; He, J; Li, Y; Lu, Y; Song, X | 1 |
| Crowley, SD; Griffiths, R; Lu, X; Privratsky, JR; Ren, J; Rudemiller, NP; Wen, Y | 1 |
| Bai, F; Bose, HS; James, EA; Sturdivant, K; Wang, NP; Zhang, WW; Zhao, ZQ; Zheng, RH | 1 |
| de Boer, RA; Koonen, DPY; Lindtstedt, EL; Michaëlsson, E; Piek, A; Schouten, EM; Silljé, HHW | 1 |
| Ren, Q; Ren, W; Ruan, Y; Wang, J; Wang, Z; Wu, Z; Yu, A | 1 |
| Dweck, MR; Fletcher, AJ; Syed, MBJ | 1 |
| Hill, JA | 1 |
| Furgeson, SB; Jolly, AJ; Lu, S; Moulton, KS; Mutryn, MF; Nemenoff, RA; Strand, KA; Tucker, RM; Weiser-Evans, MCM | 1 |
| Cui, H; Liang, H; Lv, J; Wang, H; Wang, M; Wang, S; Ye, F; Zheng, Y; Zhu, Y | 1 |
| Chen, AH; Jia, W; Liang, G; Liu, H; Qi, J; Zhang, W; Zhang, Y | 1 |
| Dang, Z; Ge, R; Jin, G; Li, Z; Lu, D; Ma, L; Nan, X; Su, S | 1 |
| Chen, MJ; Fan, G; Wei, J | 1 |
| Cicalese, S; Eguchi, S; Okuno, K | 1 |
| Abraham, NG; Arad, M; Aravot, D; Arow, M; Freimark, D; Hochhauser, E; Kornowski, R; Nudelman, V; Shainberg, A; Waldman, M; Yadin, D | 1 |
| Liu, R; Xin, LH; Yang, XW | 1 |
| Li, Q; Wang, F; Wei, X; Zhang, J; Zhang, W | 1 |
| Alonso, J; Ballester-Servera, C; Cañes, L; Galán, M; Herraiz-Martínez, A; Hove-Madsen, L; Martí-Pàmies, I; Martínez-González, J; Muniesa, P; Nistal, JF; Osada, J; Rodríguez, C | 1 |
| Fujita, M; Hung, WY; Nakagawa, K; Nakagawasai, O; Nemoto, W; Tadano, T; Tan-No, K; Yamagata, R | 1 |
| Cao, XR; Dong, B; Dong, XF; Hei, NH; Kong, J; Li, JL; Ma, H; Wang, YL | 1 |
| Ding, R; Hu, Y; Li, Q; Liu, Z; Lu, W; Xiao, H; Xie, D; Xie, J; Ye, B; Zheng, G; Zhong, L; Zhong, Y; Zhong, Z | 1 |
| Guo, D; Liu, H; Zhao, Z | 1 |
| Angermann, JE; Bender, A; Burnett, L; Evans, LW; Ferguson, BS; Godoy, L; Shen, Y; Staten, D; Zhou, T | 1 |
| Baruscotti, M; Guo, R; Liu, H; Liu, N; Wang, Y; Zhang, H; Zhang, J; Zhao, L | 1 |
| Song, W; Su, L; Yao, Y | 1 |
| Ahmed, S; Layton, AT | 1 |
| Aono, T; Arimoto, T; Goto, J; Kato, S; Kutsuzawa, D; Narumi, T; Nishiyama, S; Otaki, Y; Shishido, T; Sugai, T; Takahashi, H; Takahashi, T; Tamura, H; Toshima, T; Wanezaki, M; Watanabe, K; Watanabe, M; Watanabe, T | 1 |
| Beltz, TG; Guo, F; Hurley, SW; Johnson, AK; Xue, B | 1 |
| Chen, DR; Chen, HJ; Chen, XH; Gao, PJ; Kong, LR; Pan, XX; Ruan, CC; Wu, F | 1 |
| Chang, CW; Hsu, JH; Kuo, CH; Lai, CH; Lee, FT; Liu, CP; Wu, HL; Yeh, JL | 1 |
| Cao, XR; Dong, B; Hei, NH; Li, JL; Ma, H; Wang, YL; Yan, WJ | 1 |
| Ding, L; Lu, Q; Lu, S; Lyu, D; Ma, Z; Ouyang, C; Zhou, Y | 1 |
| Cheng, Z; Fu, XM; Li, JM; Liao, XB; Peng, HL; Wu, QY; Zhang, GS; Zhao, Y; Zhou, XM; Zhou, YZ | 1 |
| Ge, J; Ma, J; Ma, L; Ma, Y; Wu, R; Zou, Y | 1 |
| Finger, S; Garlapati, V; Karbach, SH; Knopp, T; Knorr, M; Kossmann, S; Lagrange, J; Molitor, M; Münzel, T; Nguyen, TS; Rudi, WS; Ruf, W; Schüler, R; Wenzel, P; Wild, J | 1 |
| Li, H; Li, S; Liu, G; Shen, G; Sun, Q; Wang, H; Xu, Y; Yao, Y; Yuan, C | 1 |
| Gupta, V; Gurley, SB; Hering, L; Hoch, H; Markó, L; McDonough, AA; Potthoff, SA; Rahman, M; Ralph, DL; Reil, A; Rump, LC; Stegbauer, J; Vonend, O; Yakoub, M; Yang, G | 1 |
| Jiang, F; Sun, H; Wang, H; Xu, L; Zhang, D | 1 |
| Gotoh, T; Hoshizaki, M; Imai, Y; Inagaki, T; Koyota, S; Kuba, K; Minato, T; Motoyama, S; Nakahara, K; Nakaoka, Y; Natsui, M; Nirasawa, S; Ozawa, R; Penninger, JM; Sato, T; Takahashi, S; Watanabe, H; Yamaguchi, T; Yokota, S; Yoshihashi, T; Yoshiya, T; Yoshizawa-Kumagaye, K | 1 |
| Chen, W; Wang, Y; Zhang, Y | 1 |
| Jiang, C; Lu, Y; Zhang, S | 1 |
| Cheng, K; Cheng, Z; Yao, Y | 1 |
| Fang, ZY; Jiang, WM; Mao, XJ; Zhang, SF | 1 |
| Liu, Z; Shen, J; Yin, L; Yue, J | 1 |
| Bennet, L; Davidson, JO; Drury, PP; Gunn, AJ; Kasai, M; Lear, CA; Miyagi, E | 1 |
| Cai, Q; Chen, Y; Chu, J; Huang, Y; Lin, S; Peng, J; Sankararaman, S; Sferra, TJ; Shen, A; Yu, N; Zhang, L | 1 |
| Guo, H; Lu, T; Wang, C; Wang, H; Xing, D; Yang, J; Zhong, S | 1 |
| Aoki, H; Fukumoto, Y; Furusho, A; Hashimoto, Y; Hayashi, M; Hirakata, S; Ito, S; Kuwahara, K; Majima, R; Nakao, E; Nishida, N; Nishihara, M; Ohno-Urabe, S | 1 |
| Cai, Z; Chen, Y; Fang, W; Fu, Y; Kong, W; Li, L; Li, Z; Sun, Y; Wang, L; Yang, L; Yao, F; Zhao, Z; Zhou, Y; Zhu, H | 1 |
| Chen, R; Das, S; Hua, X; Li, J; Tang, H; Wang, L; Xiao, J; Yang, T | 1 |
| Dorey, TW; Moghtadaei, M; Rose, RA | 1 |
| Chen, H; Wang, H; Zhu, J | 1 |
| Jiang, W; Lei, L; Li, Q; Ni, Y; Wan, Z; Wei, J | 1 |
| Li, L; Li, Y; Ma, W; Pan, S; Shi, X; Tian, Y; Wang, H; Xu, C | 1 |
| Franco, M; Kulthinee, S; Navar, LG; Shao, W | 1 |
| Biros, E; Golledge, J; Kleinschnitz, C; Krishna, SM; Moran, CS; Morton, SK; Panousis, C; Seto, SW | 1 |
| Batthyany, C; Bresque, M; Caggiani, M; Calliari, A; Colman, L; Contreras, P; Escande, C; Leyva, A; Liechocki, S; Maya-Monteiro, CM; Mazal, D | 1 |
| Agarwal, G; Albert, B; Calomeni, EP; Debski, A; Gadde, N; Go, MR; Hans, CP; Jones, B; Mahajan, A; Sharma, N; Tonniges, JR; Yeung, DA | 1 |
| Chang, L; Chang, Z; Chen, YE; Fan, Y; Garcia-Barrio, MT; Guo, Y; Liang, W; Lu, H; Rom, O; Sun, J; Wang, H; Xiong, W; Zhang, J; Zhao, G; Zhao, Y; Zhu, T | 1 |
| Al-Shabrawey, M; Hsiao, G; Ibrahim, AS; Tawfik, A; Wang, MH | 1 |
| Choi, ET; Cicalese, S; Cooper, HA; Eguchi, S; Kasahara, S; Kawai, T; Okuno, K; Otaka, N; Preston, KJ; Rizzo, V; Scalia, R; Uchida, HA | 1 |
| Kwaan, HC | 1 |
| Aoki, H; Fukumoto, Y; Furusho, A; Hashimoto, Y; Hayashi-Hori, M; Hirakata, S; Ito, S; Majima, R; Matsukuma, M; Nishida, N; Ohno-Urabe, S | 1 |
| An, X; Tan, A; Wang, L; Xia, Y; Xie, Y | 1 |
| Belenchia, AM; Hans, CP; Pulakat, L; Sharma, N; Toedebusch, R | 1 |
| Khalil, RA; Li, L; Li, Y; Ma, W; Pan, S; Wang, B; Wang, H | 1 |
| Kugiyama, K; Miki, Y; Murakami, M; Taketomi, Y; Watanabe, K | 1 |
| An, C; Hu, Z; Mitch, WE; Wang, Y; Wen, J | 1 |
| Chen, Y; Du, J; Jia, MZ; Liu, Y; Ning, ZP; Qi, YF; Ren, JL; Tang, CS; Yu, YR; Zhang, LS; Zhang, YR | 1 |
| Cong, W; Dong, E; Feng, Y; Hu, G; Li, M; Song, Y; Wang, S; Xiao, H; Zhang, Y | 1 |
| Chen, AD; Chen, Q; Kang, YM; Li, YH; Qiu, Y; Wu, N; Zhou, B; Zhou, H; Zhu, GQ | 1 |
| Chen, J; Guo, Y; Ji, T; Rao, Y; Xie, P | 1 |
| Danser, AHJ; de Maat, S; de Mast, Q; Maas, C; van de Veerdonk, FL | 1 |
| Ding, Y; Fu, X; Liu, F; Lou, Y; Wen, H; Yang, L; Yang, Q; Zhang, J; Zhang, L | 1 |
| Chávez-Alderete, J; Loza-Mejía, MA; Maldonado, V | 1 |
| Chen, Z; Li, H; Pan, Y; Wang, G; Zhang, H | 1 |
| Cao, HL; Chi, RF; Guo, CL; Li, B; Liu, HM; Lu, ZY; Qi, J; Wang, RY; Wang, X; Yang, B; Yang, ZM | 1 |
| Bin, J; Feng, X; He, X; Lai, Y; Liao, W; Liao, Y; Song, H; Wei, G; Xu, T; Yang, Y; Zheng, H; Zhong, L | 1 |
| Adami, E; Chen, X; Cook, SA; Corden, B; Ko, NSJ; Lim, WW; Schafer, S; Song, W; Su, L; Tee, NGZ | 1 |
| Alexander, MR; Ao, M; Chen, Y; Dale, BL; Davis, GK; Madhur, MS; Pandey, AK; Smart, CD; Xiao, L | 1 |
| Bumdelger, B; Ishida, M; Karasaki, K; Kokubo, H; Otani, M; Sakai, C; Yoshizumi, M | 1 |
| Gan, H; He, J; Li, C; Xia, W; Xia, Y; Zhao, H; Zhong, X | 1 |
| Chen, X; Lio, I; Liu, J; Wang, S; Wei, Z; Xiao, J; Yang, C; Zhang, H | 1 |
| Cassis, LA; Daugherty, A; Howatt, DA; Lu, HS; Moorleghen, JJ; Wu, C; Wu, CH | 1 |
| Chen, Z; Ding, G; Feng, J; Hu, J; Liang, W; Wang, H; Yang, D; Yang, Q; Yang, Y; Zhu, Z | 1 |
| Cui, SX; Doviak, H; Epstein, FH; French, BA; Leor, J; Sano, S; Shah, SA; Walsh, K; Wang, Y; Waters, CD | 1 |
| Finger, S; Garlapati, V; Kossmann, S; Lagrange, J; Ruf, W; Wenzel, P | 1 |
| Bao, Y; Dai, Y; Jia, K; Jin, Q; Li, X; Liu, A; Lu, L; Wu, L | 1 |
| Cheng, B; Li, S; Liu, C; Zhao, W; Zhao, Z | 1 |
| Kong, X; Li, P; Liu, C; Shen, Y; Wu, X; Yang, C | 1 |
| Brangsch, J; Buchholz, R; Hamm, B; Karst, U; Klopfleisch, R; Kosch, O; Makowski, MR; Mangarova, DB; Mohtashamdolatshahi, A; Paysen, H; Schnorr, J; Taupitz, M; Wiekhorst, F | 1 |
| Batlle, D; Kaplan, N; Lavker, RM; Lu, K; Peng, H; Wang, J; Wysocki, J; Yang, W | 1 |
| Dong, Z; Ge, J; Hu, K; Li, W; Sun, A; Sun, X; Wu, J; Yin, L | 1 |
| Baker, AH; Borthwick, G; Boswell, L; Dweck, MR; Gray, GA; Jansen, MA; Kwiecinski, J; Lennen, RJ; Newby, DE | 1 |
| Chen, Z; He, X; Liu, X; Lu, Y; Miao, R; Wang, J | 1 |
| Davis, FM; Obi, AT | 1 |
| Biessen, EA; Blankesteijn, WM; Foulquier, S; Goossens, P; Kerkhofs, D; Milanova, IV; Prickaerts, J; Schell, KJ; Unger, T; van Essen, H; van Hagen, BT; van Oostenbrugge, RJ; Wijnands, E | 1 |
| Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; Eksterowicz, J; El Mobadder, M; El-Araby, IE; El-Magd, MA; El-Tarabany, MS; Elgorban, AM; Engelmann, D; English, KL; Esfandiari, H; Eslami, B; Espinosa-Cuevas, A; Eswara, S; Faber, E; Fan, XH; Fan, Y; Fang, J; Fang, Z; Fantin, VR; Fei, P; Feng, G; Feng, H; Feng, J; Feng, X; Feng, XJ; Fennell, TR; Fernández-Moreira, V; Ferraz, ABF; Ferreras, KN; Flores, K; Flores-Pérez, I; Flox, C; Fluharty, FL; Fokouong Tchoffo, E; Folefack, GO; Foroutan, T; Fort, D; Fourati, S; Fousas, S; Frapard, T; Freguia, S; Friedman, DJ; Friedman, LS; Fu, D; Fu, Q; Fu, Y; Fujinami, S; Furihata, K; Gal, RL; Gan, H; Gao, C; Gao, F; Gao, R; Gao, SS; Gao, W; Gao, XC; Gao, Y; Gao, Z; Garozi, L; Ge, J; Georgiopoulos, A; Gerakiou, K; Ghazimirsaeed, SM; Ghazimirsaeed, ST; Gimeno, MC; Gjestad, R; Glurich, I; Goetchius, E; Goland, S; Goldstein, S; Gonçalves, CM; Gonçalves, H; Gong, Q; Gonzalez, D; Goplen, FK; Gorshkova, EN; Gotsman, I; Govindasamy, V; Granger, CB; Greco, L; Grigoriadou-Skouta, E; Grigoropoulos, P; Grivicich, I; Gromov, NV; Gruber, S; Grytczuk, M; Grzech-Leśniak, K; Gu, L; Gu, S; Gu, Z; Guadagnini, D; Guan, H; Guilliams, M; Guo, J; Guo, L; Gupta, A; Gupta, SK; Gurzu, S; Gutleb, AC; Haban, A; Hablitz, JJ; Hadisuyatmana, S; Hahn, S; Haiges, R; Hallal-Calleros, C; Hamed, M; Hammad, N; Hammer, N; Han, C; Hao, Y; Harnett, J; Has, EMM; Hassanpour, K; Hatzopoulos, D; Hawaldar, R; He, X; He, Y; He, YY; He, Z; Heberman, D; Heckl, D; Hegde, H; Henson, MA; Hernández-Velázquez, VM; Herrera, E; Hijazi, Z; Hirayama, K; Hirth, JM; Hoeben, A; Hohnloser, SH; Hong, M; Hood, K; Hoplock, LB; Hopman, WM; Horlbogen, LM; Hossein Rashidi, B; Hou, G; Hou, H; Hou, J; Hou, Y; Hu, J; Hu, W; Hu, X; Hua, W; Huang, G; Huang, H; Huang, J; Huang, T; Huang, W; Huang, Y; Huang, YD; Huang, Z; Hudis, CA; Hue, S; Huo, J; Hussain, M; Hvas, AM; Ichii, T; Ide Zeuna, J; Ilyas, S; Inoue, T; Iranzo, A; Irfan, M; Iwasa, Y; Iwashita, Y; Izgorodina, EI; J R, A; Jaber, WA; Jaborek, JR; Jacobus, SJ; Jadeja, SD; Jafarabadi, M; Jalan, D; Jamil, MI; Jarrah, S; Jarvis, D; Jayatilaka, KAPW; Jemal-Turki, A; Jeon, YK; Jeong, N; Jeong, SH; Jeong, SY; Jermy, M; Jhaveri, K; Ji, H; Ji, K; Ji, RY; Jiang, F; Jiang, J; Jiang, X; Jiang, Y; Jiao, Q; Jilani, K; Jiménez-Guerrero, P; Jin, L; Jo, YH; Johnson, JG; Johnson, ML; Jones, WS; Jose, S; Jularic, M; Jung, I; Jung, YJ; Jungen, C; Junttila, MR; Kache, S; Kahanovitch, U; Kalantzi, KI; Kallio, T; Kamnoedboon, P; Kang, CH; Kang, H; Kang, J; Kang, KW; Kapoor, P; Karmakar, D; Kartalis, A; Kauranen, P; Kazocina, A; Keikha, F; Keltai, M; Kershaw, SV; Kettani, M; Khalvati, S; Khandhar, S; Khosla, N; Kiely, CJ; Kim, CC; Kim, H; Kim, MJ; Kim, Y; Kim, YH; Kim, YT; Kimoto, E; Kiyu, A; Klatt, N; Kobayashi, M; Koh, J; Köhler, R; Kondadasula, SV; Kong, H; Kong, W; Kong, X; Kotidis, A; Kotwal, A; Kouvari, M; Kozhinov, AN; Kruger, D; Kuang, S; Kuang, Y; Kubota, M; Kuklik, P; Kumar, P; Kumar, SK; Kuo, YF; Kurup, SP; Kusuhara, H; Kuswanto, H; Lacouture, ME; Lambin, P; Lang, CC; Langroudi, FH; Lanman, RB; Larsen, OH; Laskin, J; Le, VH; Leach, M; Lee, BG; Lee, DF; Lee, DS; Lee, HJ; Lee, SB; Lee, YA; Lei, Y; Lekashvili, O; Lelj, F; Lemin, AS; Lemoine, J; Leuschner, R; Li, B; Li, BT; Li, C; Li, D; Li, F; Li, G; Li, H; Li, HW; Li, J; Li, M; Li, P; Li, Q; Li, S; Li, W; Li, X; Li, XY; Li, Y; Li, Z; Lian, Y; Liang, C; Liao, J; Liao, W; Liao, Y; Lin, D; Lin, W; Lin, YL; Lindbäck, J; Lindsay, AP; Ling, J; Linser, PJ; Liu, C; Liu, H; Liu, JJ; Liu, L; Liu, Q; Liu, SF; Liu, X; Liu, Y; Liu, Z; Liu, ZM; Lo Sterzo, C; Lo, ECM; Lobchuk, MM; Lodge, TP; Logotheti, S; Lonial, S; Lopes, G; Lopes, RD; Lopez, J; Lopez, SA; López-Santos, AL; López-Sendón, JL; Loring, Z; Louis, C; Lovita, AND; Lu, DZ; Lu, H; Lu, J; Lu, K; Lu, TT; Lu, Y; Luengo, A; Lum, LG; Luna, JM; Luo, L; Luo, R; Luo, T; Luo, X; Luo, Z; Lv, B; Lymperopoulos, N; Lyras, A; Lyu, Y; M Kannan, A; Ma, H; Ma, M; Ma, Q; Ma, S; Ma, WY; Ma, Y; Maalouf, E; Machado, FA; Maeda, K; Magrans, JO; Maharani, A; Maia, G; Mainwaring, RD; Maji, TK; Majumdar, K; Mannarino, MR; Mansuri, MS; Marinescu, SC; Markatos, G; Marquardt, S; Marraiki, N; Martens, C; Martínez, TJ; Marumo, K; Maruyama, H; Marwani, HM; Marzo, I; Masrati, G; Matamba, P; Mathialagan, S; Matys, J; Mayatra, JM; Mboua, PC; McArthur, T; McCrimmon, RJ; McIntosh, S; McSpadden, S; Medina-Campos, ON; Medvedovsky, AT; Mei, Z; Mekontso-Dessap, A; Menezes, AMB; Meng, J; Meng, P; Meng, Y; Menter, A; Mets, MB; Mets-Halgrimson, R; Metzger, T; Metzler-Nolte, N; Meyer, C; Mi, Y; Michailoviene, V; Mikrogeorgiou, A; Militz, H; Miller Iii, TF; Minarowska, A; Mir, S; Miron, I; Miyake, T; Moayer, F; Modi, S; Moeller, SJ; Mohamad, MN; Mohammed, EHM; Mokhonov, VV; Mondal, A; Moore, J; Moravcova, M; Mordi, IR; Mordi, NA; Mortensen, NP; Moscariello, C; Moser, J; Moynahan, ME; Mu, J; Mu, W; Mudduwa, LKB; Mukherjee, S; Mukhtar, A; Mulkey, DK; Murr, N; Mushtaq, Z; Muthuswamy, N; Mutlu, O; Muto, C; Myroforou, I; Na, KJ; Nabi, M; Nagornov, KO; Nagy, RJ; Naik, A; Nakajima, K; Nam, KT; Nam, YW; Namburath, M; Nammour, S; Namour, A; Namour, M; Nanan, S; Natsume, H; Nave, S; Naveed, A; Nazir, H; Ndubaku, C; Nedospasov, SA; Neradilek, MB; Newcomb, C; Nguépy Keubo, FR; Nguyen, M; Ning, J; Ning, Q; Noguchi, S; Nordahl, SHG; Nordfalk, KF; Norton, L; Noupoue, EM; Nouri, SS; Nowak, JK; Núñez, K; Oakes, K; Odegaard, JI; Ogorodnikova, OL; Ogunsuyi, O; Oh, HK; Oh, HR; Oh, KH; Ohgi, K; Okunade, KS; Oliveira, AG; Olorunfemi, G; Olsen, ML; Olson, BA; Omari, KW; Ondruschka, B; Orfali, R; Orkopoulos, A; Orlowski, RZ; Oser, SM; Oser, TK; Özcan, M; Padilla, V; Paeng, JC; Pajuelo-Lozano, N; Pal, SK; Palmieri, S; Palomeque, E; Pan, W; Panagiotakos, DB; Pandey, M; Pang, D; Pang, Q; Pangarah, CA; Panny, A; Paparella, A; Papirio, S; Papouskova, K; Parang, K; Park, HJ; Park, IK; Park, S; Parker, TL; Parkhomenko, A; Parmon, VN; Parsons, B; Parsons, J; Patel, PR; Patil, S; Patsourakos, NG; Patterson, KC; Pavlidis, P; Pedernera, M; Pedersen, R; Pedraza-Chaverri, J; Pellegrini, M; Peña-Chora, G; Pereira, EDM; Pereira, MADS; Peretz, A; Perez-Padilla, R; Perlman, GY; Perona, R; Petras, C; Phuntsho, S; Picada, JN; Pinder, TA; Piper, LFJ; Pirozzi, F; Pirro, M; Pleckaityte, M; Ploutz-Snyder, LL; Ploutz-Snyder, R; Pogorzelski, A; Poles, L; Postma, AA; Prager, A; Prakash, J; Punn, R; Pützer, BM; Qi, J; Qi, MC; Qi, Y; Qian, J; Qian, Y; Qiang, L; Qiu, J; Qu, Y; Rabiu, KA; Rahighi, S; Rahman, MM; Rahmani, B; Rajkumar, SV; Ramanathan, R; Raras, TYM; Rashi, Y; Rasool, G; Rathore, MG; Ratnawati, R; Ratola, N; Raucci, U; Ray, SK; Razavi, P; Razazi, K; Razek, S; Razi, SS; Reback, M; Reddy, K; Rees, DC; Reginatto, FH; Reich, H; Reis-Filho, JS; Ren, X; Ren, Y; Renner, G; Rey, G; Reymen, B; Riaz, M; Ricci, A; Richardson, PG; Richter, C; Riga, M; Ritchie, C; Rivoal, S; Roberts, W; Robson, ME; Rocha, GZ; Rodrigues, AD; Rogach, AL; Rojas, A; Rosenberg, A; Rosenberg, E; Rosenheck, RA; Roslan, K; Rothenberger, C; Rouschop, KMA; Rubagumya, F; Ryan, CM; Ryder, JW; Saad, MJA; Sacan, O; Sacchi, A; Sahebkar, A; Saini, A; Sainz, B; Sajo, EA; Sakizadeh, J; Saleh, AA; Salgado Júnior, IB; Salvi, R; Samoylova, YV; Samuni, A; Sanchez, DM; Sanchez-Perez, I; Santos, M; Sarapulova, A; Sardot, T; Saud, N; Sauerbier, P; Scaltriti, M; Schaeffer, B; Schalk, DL; Scherschel, K; Schijven, MP; Schreuder, HWR; Schuhmacher, M; Schultz-Lebahn, A; Schwarzl, J; Scott, JM; Sebayang, SK; Seeger, ZL; Segabinazi Peserico, C; Selenica, P; Serio, A; Seruga, B; Shah, A; Shah, C; Shah, PD; Shahrokh Tehraninezhad, E; Shan, A; Shao, Z; Sharma, AMR; Sharma, RK; Shen, J; Shen, R; Shi, X; Shi, Y; Shi, ZE; Shih, YC; Shimohata, H; Shimpi, N; Shin, SH; Shon, HK; Shuvy, M; Siddique, AB; Siegbahn, A; Sikandar, M; Silvani, Y; Singh, A; Singh, AK; Singh, D; Singh, JS; Singh, KP; Singh, M; Situ, B; Skipper, MT; Skouloudi, M; Sloane, BF; Smyrnioudis, N; Snyder, MA; Söhnchen, C; Solis Condor, R; Solit, DB; Someya, S; Song, H; Song, J; Song, W; Song, Y; Sorokina, KN; Soshi, S; Soyer, P; Spitschak, A; Sreekrishnan, TR; Srinivasan, M; Staruschenko, A; Steel, A; Stefan-van Staden, RI; Stein, AM; Strayer, H; Struthers, AD; Su, H; Su, Q; Su, X; Sudore, RL; Sugimura, H; Sugiyama, Y; Sujuti, H; Sumner, SJ; Sun, B; Sun, D; Sun, H; Sun, J; Sun, JY; Sun, X; Sun, Y; Sun, Z; Sung, YC; Surenaud, M; Sutimantanapi, D; Suwandaratne, NS; Swaroop, S; Sychrova, H; Syed, A; Szczepanik, M; Szederjesi, J; Szodorai, R; Tacy, TA; Tadelle, RM; Takayasu, M; Tammeveski, K; Tan, H; Tan, M; Tang, HX; Tang, S; Tang, X; Tanokura, M; Tao, F; Tao, H; Tarafdari, A; Tarín-Carrasco, P; Tasson Tatang, C; Teixeira, JP; Thakur, A; Theobald, A; Thevenot, P; Thomaidis, K; Tian, J; Tillib, SV; Toma, C; Tomita, M; Tonchev, I; Tong, F; Toy, W; Trypuć, M; Tselepis, AD; Tsetseris, L; Tsikouri, GE; Tsikouris, EI; Tsoplifack, CB; Tsoumani, ME; Tsujimoto, R; Tsybin, YO; Tu, J; Tu, TM; Turco, M; Turkyilmaz, IB; Uddin, MJ; Ung, J; Unsihuay, D; Utsunomiya, T; Vagenende, B; Vaishnav, J; Valdes, C; Validad, MH; Valle, J; van Ginkel, MPH; van Grevenstein, WMU; Vanderpuye, V; Vasan, N; Vasilenko, EA; Vasques, GJ; Vavoulis, P; Verani, A; Veziroglu, E; Viegas, A; Vitali, MG; Vitsas, G; Voccio, JP; Vogiatzidis, C; Volow, A; Volpin, F; Vourvahis, M; Wagner, LI; Walkowiak, J; Wallace, R; Wallentin, L; Wan, D; Wan, L; Wan, T; Wang, C; Wang, F; Wang, FN; Wang, H; Wang, J; Wang, L; Wang, Q; Wang, S; Wang, T; Wang, W; Wang, X; Wang, XW; Wang, Y; Wang, YS; Wang, Z; Ward, J; Ward, L; Waseem, R; Watson, DF; Weber, P; Wehrmeister, FC; Wei, CH; Wei, H; Wei, L; Wei, Q; Wei, Y; Weinstock, RS; Weiss, M; Welborn, M; Wen, L; Wen, LM; Wen, Q; Wen, Z; Wesseling, P; Westerbergh, J; White, K; Wick, MP; Willems, S; Wiyasa, IWA; Wójciak, R; Wolkenhauer, O; Won, HH; Wong, J; Woo, YC; Wood, LS; Wu, CT; Wu, CY; Wu, D; Wu, G; Wu, J; Wu, K; Wu, M; Wu, Q; Wu, T; Wu, W; Wu, X; Wu, XT; Wu, Y; Xi, D; Xi, J; Xiang, W; Xiang, Y; Xiao, M; Xiao, Z; Xie, H; Xie, Q; Xie, S; Xie, X; Xing, M; Xing, YL; Xu, C; Xu, X; Xu, Y; Xu, Z; Xue, F; Xue, XD; Yaglioglu, HG; Yamada, H; Yamashita, M; Yan, W; Yan, Z; Yanardag, R; Yang, D; Yang, H; Yang, K; Yang, QQ; Yang, R; Yang, S; Yang, T; Yang, X; Yang, Y; Yao, H; Yao, Y; Yari, D; Yassin, MT; Ye, C; Ye, J; Ye, Q; Yildiz, EA; Ying, S; Yoon, H; Yu, D; Yu, K; Yu, N; Yu, PL; Yuan, C; Yuan, D; Yuan, LJ; Yuan, Z; Yuen, N; Zagatto, AM; Zakaria, Y; Zalewski, AM; Zamora, S; Zavorotinskaya, T; Zeid, JL; Zeinoun, T; Zeng, C; Zerby, HN; Zhan, X; Zhang, A; Zhang, D; Zhang, E; Zhang, F; Zhang, H; Zhang, J; Zhang, L; Zhang, M; Zhang, P; Zhang, Q; Zhang, QY; Zhang, RG; Zhang, S; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, CK; Zhao, H; Zhao, J; Zhao, K; Zhao, Q; Zhao, S; Zhao, T; Zhao, XQ; Zhao, Y; Zhao, Z; Zheng, J; Zheng, L; Zheng, Y; Zhou, B; Zhou, G; Zhou, L; Zhou, T; Zhou, X; Zhu, C; Zhu, J; Zhu, Y; Zhu, ZQ; Zhuang, T; Zimmermannova, O; Zin, NNINM; Zisimos, K; Zoghebi, KA; Zonder, JA; Zou, C; Zwirner, J | 1 |
| Boogerd, CJ; de Boer, RA; Dokter, MM; Lam, CSP; Markousis-Mavrogenis, G; Meems, LMG; Schouten, EM; Silljé, HHW; Voors, AA; Westenbrink, BD; Withaar, C | 1 |
| Li, Y; Liu, L; Ruan, Z; Wang, G; Wang, R; Zhu, L | 1 |
| Cai, Z; Huang, J; Ou, Y; Pan, B; Wang, W; Wang, X; Yang, J; Yang, P | 1 |
| Busch, K; Engelhardt, S; Esfandyari, D; Fischer, M; Ishikawa-Ankerhold, H; Klapproth, K; Klösges, L; Kobayashi, Y; Liu, L; Massberg, S; Messerer, D; Molkentin, JD; Percin, G; Perdiguero, EG; Schleifer, C; Schneider, V; Schulz, C; Schwanenkamp, J; Stremmel, C; Thaler, R; Titova, A; Vagnozzi, RJ; Waskow, C; Weinberger, T | 1 |
| Cho, MJ; Jeong, SJ; Jung, IH; Kim, S; Ko, NY; Lee, SH; Min, JK; Oh, GT; Park, JG | 1 |
| Arshad, M; Böckler, D; Dihlmann, S; Hakimi, M; Wortmann, M | 1 |
| Clarke, MW; Golledge, J; Krishna, SM; Moran, CS; Morton, SK; Moxon, JV; Nsengiyumva, V; Seto, SW | 1 |
| Aslanidou, L; Di Lorenzo, A; Lovric, G; Sasset, L; Stergiopulos, N; Trachet, B | 1 |
| Alzamora, AC; Barbosa, CM; Barbosa, MA; Campagnole-Santos, MJ; de Sousa, GG; Lima, TC; Souza Dos Santos, RA | 1 |
| Ding, M; Guo, S; Lao, M; Li, L; Wang, Q; Xu, Z | 1 |
| Ding, H; Hu, K; Huang, H; Liu, P; Luo, Y; Xiong, M; Xu, Y; Yi, J; Zhu, L | 1 |
| Chuma, M; Goda, M; Hosooka, M; Ishizawa, K; Izawa-Ishizawa, Y; Kagimoto, Y; Kondo, M; Matsuoka, R; Saito, N; Takechi, K; Tsuneyama, K; Yagi, K; Zamami, Y | 1 |
| Heng, CKM; Liao, W; Mei, D; Tan, WSD; Wong, WSF | 1 |
| Chai, CY; Chen, IC; Dai, ZK; Hsu, JH; Lin, JY; Liu, YC; Wu, BN; Yeh, JL | 1 |
| Kurashiki, T; Miyake, T; Morishita, R; Nakagami, H; Nishimura, M | 1 |
| Ali, Y; Dohi, K; Goto, I; Hashizume, R; Ito, M; Ito, R; Kobayashi, I; Kobayashi, Y; Nishikawa, M; Nishimura, Y; Okamoto, R; Saito, S; Sawa, Y; Tanaka, T; Yoshida, Y | 1 |
| Brewer, AC; Harrison, CB; Markovinovic, A; Mayr, M; Richards, DA; Santos, CXC; Sawyer, G; Shah, AM; Trevelin, SC; Yin, X; Zhang, M; Zhang, X | 1 |
| Chess-Williams, R; Hashitani, H; Kameda, M; Lim, I; Mitsui, R; Sellers, DJ | 1 |
| Gao, F; Hu, X; Jin, SW; Li, M; Lu, JC; Lu, SY; Wang, Q; Yang, JX; Zheng, SX | 1 |
| Chau, LY; Chen, IM; Chen, JW; Chen, YH; Chiang, MT; Hsu, FF; Hsu, YW; Huang, PH; Leu, HB; Liu, FT; Tsai, MS | 1 |
| Kamkar-Del, Y; Mohebbati, R; Shafei, MN | 1 |
| Andrade, CAF; Andrade-Franzé, GMF; De Luca, LA; Menani, JV; Pereira, ED; Samson, WK; Yosten, GLC | 1 |
| Huang, Z; Kong, LY; Li, YP; Tian, XY; Wang, ZM; Wu, LM; Yao, R; Zhang, DH; Zhang, JL; Zhang, YZ | 1 |
| Li, X; Lu, Y; Ma, Q; Tan, H; Tie, Y; Zhang, X | 1 |
| Du, W; Hu, J; Li, W; Li, Y; Liu, F; Wang, X; Xu, L; Yang, L; Yue, Q; Zhao, R | 1 |
| Beltz, TG; Felder, RB; Johnson, AK; Wei, SG; Xue, B; Xue, J; Yu, Y | 1 |
| Choy, A; Chung, MK; Khodadadi-Jamayran, A; Lin, X; Narke, D; Offerman, E; Park, DS; Shaheen, D; Shekhar, A; Van Wagoner, DR; Wass, SY; Xiao, J; Yamaguchi, N | 1 |
| Cai, L; Ding, Y; Fu, W; Li, X; Shi, Z; Tang, H; Xie, T; Zhou, M | 1 |
| Chen, JX; Feng, X; He, X; Su, H; Zeng, H | 1 |
| Li, D; Li, G; Lv, D; Ouyang, J; Peng, L; Shang, F; Wang, R; Yan, J; Yang, J | 1 |
| Furuta, M; Ishida, Y; Kimura, A; Kondo, T; Kuninaka, Y; Mukaida, N; Nosaka, M; Taruya, A | 1 |
| Arnaoutakis, GJ; Chun, C; Jiang, Z; Pruitt, EY; Qi, X; Saldarriaga, L; Upchurch, GR; Wang, F | 1 |
| Du, J; Hu, H; Pei, H; Shen, Y; Xu, R; Yang, D; Yang, Y | 1 |
| Gao (高晶), J; Huang (黄程淋), C; Shen (沈伟利), W; Song (宋蓓), B; Sun (孙孟炜), M; Wei (魏彤), T | 1 |
| Bang, M; Choi, HJ; Jang, KB; Kwon, MS; Lee, SH; Park, HS; Yang, B; Yoo, J; You, MJ | 1 |
| Benetti, A; Girardi, ACC; Luchi, WM; Martins, FL; Seguro, AC; Sene, LB; Shimizu, MHM | 1 |
| Arshad, M; Böckler, D; Dihlmann, S; Hakimi, M; Peters, AS; Wortmann, M | 1 |
| Alonso, J; Ballester-Servera, C; Briones, AM; Cañes, L; Martí-Pàmies, I; Martínez-González, J; Rodríguez, C; Serrano, E | 1 |
| Chen, L; Chen, X; Hou, Y; Hu, Y; Lin, Y; Lv, X | 1 |
| Bai, L; Choi, SY; Jeong, MH; Kee, HJ; Kee, SJ; Kim, GR; Kook, H; Seok, YM | 1 |
| Bullock, M; Campbell, WB; Clifton-Bligh, R; Kasparian, AO; Levick, SP; Lim, G; McCaffrey, SL; Widiapradja, A | 1 |
| Chen, X; Chen, Y; Cheng, Y; Chu, J; Li, J; Lin, X; Liu, L; Peng, J; Shen, A; Shen, Z; Wu, M; Wu, X | 1 |
| Feng, Y; Wang, W; Wu, X; Xu, L; Yu, Z; Zhang, M; Zhang, S; Zhou, X | 1 |
| Ganeva, MG; Genov, NV; Georgiev, TK; Hadzhibozheva, PV; Ilieva, GS; Nancheva, KG; Pashova-Stoyanova, LZ; Sandeva, RV; Tolekova, AN; Tsokeva, ZI | 1 |
| Chen, P; Cheng, Q; Li, J; Liu, J; Lu, L; Miao, N; Ni, J; Wang, X; Wang, Y; Xie, H; Xu, D; Yin, F; Zhang, W; Zheng, P; Zhou, L; Zhou, Z | 1 |
| Egashira, K; Katsuki, S; Koga, JI; Matoba, T; Nakano, K; Nakashiro, S; Tsutsui, H; Umezu, R | 1 |
| Bers, DM; Bossuyt, J; Hegyi, B; Ko, CY | 1 |
| Dehe, L; Habazettl, H; Mousa, SA; Nordine, M; Schäfer, M; Schluchter, H; Shakibaei, M; Shaqura, M; Treskatsch, S; von Kwiatkowski, P | 1 |
| Gu, J; Ji, Y; Lu, Y; Qian, Z; Qiu, M; Sun, W | 1 |
| Chen, Y; Du, J; Jia, LX; Jia, MZ; Liu, X; Lu, WW; Ni, XQ; Ning, ZP; Qi, YF; Ren, JL; Tang, CS; Yu, YR; Zhang, LS; Zhang, YR; Zhu, Q | 1 |
| Annapragada, AV; Devkota, L; Ghaghada, KB; LeMaire, SA; Ren, P; Shen, YH; Starosolski, Z; Stupin, IV; Tanifum, EA; Vela, D; Zhang, C | 1 |
| Chen, T; Chen, W; Feng, H; Guo, C; Jia, Z; Li, C; Li, M; Liu, X; Shi, J; Tang, X; Wang, J; Xia, M; Yin, Y | 1 |
| Chen, J; Chen, Y; Fang, L; Gao, H; Li, H; Lin, J; Lv, R; Lyu, L; Wang, W; Xu, F; Yan, T | 1 |
| Błyszczuk, P; Czepiel, M; Diviani, D; Eriksson, U; Jaźwa-Kusior, A; Kania, G; Rolski, F; Siedlar, M; Smolenski, RT; Tkacz, K | 1 |
| Chen, Y; Lai, S; Li, F; Li, Y; Liu, B; Sun, B; Wang, H; Wang, W; Zhang, X; Zheng, Y | 1 |
| Cheng, Y; Gu, W; Li, Z; Sun, T; Wang, S | 1 |
| Chen, X; Leite, APO; Li, XC; Rubera, I; Tauc, M; Zhang, L; Zhao, C; Zheng, X; Zhou, X; Zhuo, JL | 1 |
| Gao, P; LeMaire, SA; Long, X; Luo, W; Maegdefessel, L; Miano, JM; Shan, S; Shen, YH; Singer, HA; Slivano, OJ; Tabuchi, A; Zhang, W; Zhao, J | 1 |
| Bobadilla Lugo, RA; Tufiño, C; Vanegas, M; Velázquez Nevárez, R; Villanueva López, C | 1 |
| Bovée, DM; Clahsen-van Groningen, MC; Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Hoorn, EJ; Huang, S; Kim, JB; Lu, X; Melton, L; Poglitsch, M; Ren, L; Uijl, E; van Veghel, R; Zlatev, I | 1 |
| Andrade, MA; Bourque, CW; Hicks, AI; Levi, DI; Prager-Khoutorsky, M; Toney, GM; Wyrosdic, JC | 1 |
| Jeong, MH; Kee, HJ; Kee, SJ; Kim, GR; Zhao, T | 1 |
| Balakrishnan, A; Howatt, DA; Javidan, A; Jiang, W; Moorleghen, JJ; Muniappan, L; Okuyama, M; Saido, TC; Subramanian, V; Thiagarajan, D; Uchida, HA; Yang, L | 1 |
| Audu, C; Billi, AC; Daugherty, A; Davis, FM; denDekker, A; Gallagher, KA; Gudjonsson, JE; Joshi, AD; Kunkel, SL; Lu, HS; Melvin, WJ; Moore, BB; Obi, AT; Tsoi, LC; Wasikowski, R; Wolf, S; Xing, X | 1 |
| Adler, J; Aïssi, D; Duque Escobar, J; Längst, N; Lukowski, R; Müller, C; Schweigert, O; Tong, T; Trégouët, DA; Zeller, T | 1 |
| Cai, L; Collins, DM; Duan, Q; King, C; Kutz, LC; Lingrel, JB; Marck, PV; Pessoa, MT; Pierre, SV; Tian, J; Wang, X; Xie, JX; Xie, Z; Xu, Y; Yan, Y | 1 |
| Alexis, JD; Ashton, JM; Burke, RM; Dirkx, RA; Lighthouse, JK; Mohan, A; O'Brien, M; Phipps, RP; Quijada, P; Small, EM; Woeller, CF; Wojciechowski, W | 1 |
| Daugherty, A; Howatt, DA; Kukida, M; Lu, HS; Moorleghen, JJ; Ohno-Urabe, S; Poglitsch, M; Sawada, H | 1 |
| Hu, C; Kohan, DE; Min Cho, J; Peterson, CS; Ramkumar, N; Stuart, D; Symons, JD; Wheatley, W | 1 |
| Boodagh, P; Ghim, M; Gona, K; Graham, M; Han, J; Jung, JJ; Kukreja, G; Liu, X; Rajendran, S; Sadeghi, MM; Salarian, M; Sanzida, N; Toczek, J; Wei, L; Zhang, J | 1 |
| Althagafi, MG; Besla, R; Byrne, JS; Chen, Y; Cybulsky, MI; Li, A; Lindsay, T; Pacheco, S; Robbins, CS; Ulndreaj, A | 1 |
| de Gannes, M; Koch, SE; Puga, A; Rubinstein, J | 1 |
| Arendt, BK; Ebtehaj, S; Franchi, F; Lanza, IR; Parvizi, M; Rodriguez-Porcel, M | 1 |
| Bando, YK; Fang, L; Hiramatsu-Ito, M; Kato, K; Kawanishi, H; Murohara, T; Ogawa, H; Ohashi, K; Otaka, N; Ouchi, N; Ozaki, Y; Shibata, R; Shimizu, Y; Takefuji, M; Takikawa, T | 1 |
| Chen, C; Chen, E; Gan, L; Guan, X; He, Y; Hu, H; Jiang, W; Liu, B; Liu, D; Liu, J; Liu, L; Ma, W; Tang, S; Xin, H; Xue, J; Zhang, Y | 1 |
| Chai, D; Chen, X; Chu, Y; Du, H; Lin, J; Lin, X; Liu, J; Ma, K; Ruan, Q; Xie, H; Xu, C; Zeng, J; Zhang, H; Zhang, Y | 1 |
| Chen, C; Lu, Q; Shi, JY; Su, YL; Xu, X | 1 |
| Du, WY; Gao, H; Han, SL; Lin, J; Sun, XF; Zhang, YJ | 1 |
| Brombacher, F; Frieler, RA; Goldstein, DR; Goonewardena, SN; Ma, J; Mortensen, RM; Song, J; Vigil, TM | 1 |
| Abreu, TP; Barahuna-Filho, PFR; Caruso-Neves, C; Cebotaru, L; Cheng, J; Guggino, WB; Peruchetti, DB; Pinheiro, AAS; Silva-Aguiar, RP; Takiya, CM | 1 |
| Chen, C; Feng, J; Guo, Y; Qin, Q; Ren, B; Yang, N | 1 |
| Bu, P; Hu, Y; Li, N; Liu, J; Liu, L; Qi, Y; Suo, M; Xie, L; Zhang, C; Zheng, X | 1 |
| Cai, L; Ding, Y; Li, X; Shi, Z; Tang, H; Zhou, M | 1 |
| Ham, W; Kang, CW; Kang, H; Kim, J; Lee, WS; Ock, S | 1 |
| Alexander, B; Casarini, DE; Hassan, R; Leite, APO; Li, XC; Zheng, X; Zhuo, JL | 1 |
| Chan, YH; Chen, SW; Chou, AH; Chou, SH; Chu, PH; Ho, CT; Hsiao, FC; Hsu, ME; Kao, WWY; Lin, PJ; Tung, YC; Wu, VC | 1 |
| Han, JH; Li, WZ; Wu, WN; Xue, HX; Yin, YY; Yu, YG | 1 |
| Gao, PJ; Guo, YT; He, S; Li, SJ; Li, XD; Lu, X; Lu, YY; Shao, S; Wang, RQ; Zhou, HD | 1 |
| Fan, S; Niu, Y; Qin, J; Shi, Y; Wang, J; Xiong, Q; Zhang, L; Zhang, X | 1 |
| Han, Q; Li, H; Shi, H; Xue, H; Zhang, F; Zhang, Y | 1 |
| Arioka, M; Hosoda, H; Ishikane, S; Kitazono, T; Sasaguri, T; Takahashi-Yanaga, F; Takiguchi, T; Tetsuo, F | 1 |
| De Gregorio, N; Díaz-Araya, G; Espinoza, C; Espitia-Corredor, J; Lavandero, S; Olivares-Silva, F; Osorio, JM; Peiró, C; Sánchez-Ferrer, C; Silva, D; Vivar, R | 1 |
| Chang, J; Du, J; Ge, X; Li, X; Li, YC; Liu, W; Nie, H; Sun, Y; Wei, X; Xun, Z | 1 |
| Dong, N; Klenotic, PA; Li, R; Lin, Z; Narla, G; Wang, Y; Wei, W; Xie, F; Xu, Q; Zhang, C; Zhou, X | 1 |
| Akita, K; Isobe, S; Isoda, K; Iwakura, Y; Minamino, T; Niida, T; Ohtomo, F; Sano, M; Sato-Okabayashi, Y; Shimada, K | 1 |
| Cheng, T; Fan, P; Hua, C; Wang, J; Xia, Q; Zhang, L; Zhao, L; Zhou, J | 1 |
| Li, J; Ye, Y; Yu, WQ; Zhang, JH | 1 |
| Balboa, A; Becirovic-Agic, M; Busch, A; de Waard, V; Gäbel, G; Golledge, J; Holdt, LM; Lindeman, JHN; Ludwig, S; Maegdefessel, L; Mahlmann, A; Northoff, BH; Petri, M; Teupser, D; Wågsäter, D; Wanhainen, A | 1 |
| Bar, A; Chlopicki, S; Enggaard, C; Hansen, PBL; Jasztal, A; Jensen, B; Kieronska-Rudek, A; Kij, A; Marczyk, B; Mateuszuk, L; Matyjaszczyk-Gwarda, K; Proniewski, B; Przyborowski, K; Tworzydlo, A; Walczak, M | 1 |
| Li, JD; Wu, MP; Xu, X; Yan, C; Zhang, YS; Zhou, Q | 1 |
| Han, J; Huang, W; Li, W; Li, X; Liang, G; Lum, H; Shan, X; Xu, Z; Yu, W; Zou, C | 1 |
| Chen, H; Hu, R; Liu, C; Shao, J; Xie, P; Yang, D | 1 |
| Akazawa, H; Isobe, M; Koriyama, H; Mochizuki, H; Morishita, R; Nakagami, H; Shimamura, M; Suzuki, JI; Wakayama, K; Watanabe, R | 1 |
| Clancy, P; Crossman, DJ; Emeto, TI; Golledge, J; Jose, R; Krishna, SM; Li, J; Moxon, J; Norman, P; Seto, SW | 1 |
| Li, Y; Lu, G; Sun, D; Wang, DW; Yan, J; Zuo, H | 1 |
| Fukamizu, A; Ho, L; Imai, Y; Ishida, J; Ito, H; Kadowaki, A; Kimura, A; Kuba, K; Penninger, JM; Reversade, B; Sato, C; Sato, T; Watanabe, H; Yamaguchi, T | 1 |
| Chen, W; Chen, X; Huang, F; Khan, A; Li, L; Qiu, Z; Wang, L; Wang, X; Zhang, J | 1 |
| Allen, BG; Chatenet, D; Fournier, A; Harada, M; Merlen, C; Nattel, S; Naud, P; Qi, X; Surinkaew, S; Tadevosyan, A; Xiao, J | 1 |
| Alenina, N; Bader, M; Danser, AHJ; Domenig, O; Essers, J; Garrelds, IM; Góes Martini, A; Leijten, FPJ; Paulis, L; Poglitsch, M; Qadri, F; Rajkovicova, R; Severs, D; Te Riet, L; Uijl, E; van der Pluijm, I; van Thiel, BS | 1 |
| Chen, D; Coffman, TM; Gurley, SB; Herrera, M; Königshausen, E; Sparks, MA; Stegbauer, J; Yang, T | 1 |
| Davidge, KN; Gonzalez, FJ; Katsurada, A; Khan, NS; Majid, DSA; Malik, KU; Navar, LG; Pingili, AK; Thirunavukkarasu, S | 1 |
| Cao, C; Hasegawa, Y; Kim-Mitsuyama, S; Koibuchi, N; Lin, B; Takane, K; Yokoo, T | 1 |
| Qian, J; Sun, B; Wang, H; Xing, C; Zhao, X | 1 |
| Bhindi, R; Birgisdottir, AB; Bubb, KJ; Figtree, GA; Hansen, T; Karimi Galougahi, K; Kok, C; Meyer, C; Rasko, NB; Reisman, SA; Ritchie, R; Tang, O; Ward, K | 1 |
| Chen, J; Chen, XM; Hou, JW; Li, G; Li, W; Li, YG; Wang, H; Wang, Q; Wang, YP; Wei, SS; Xu, WP; Zhou, Q | 1 |
| Gao, Q; Jiang, T; Ou, Z; Shi, JQ; Tian, YY; Wu, L; Zhang, YD; Zhou, JS | 1 |
| Cohen, IS; Jiang, YP; Kim, JH; Lin, RZ; Mathias, RT | 1 |
| Bu, P; Huang, C; Li, J; Li, N; Liu, H; Shan, X; Yan, X; Yang, Y; Zhang, C; Zhang, J; Zhang, P; Zhang, Y | 1 |
| Antunes, E; Bonilla-Becerra, SM; Calmasini, FB; de Oliveira, MG; Rojas-Moscoso, JA; Zanesco, A | 1 |
| Itano, S; Kadoya, H; Kashihara, N; Sasaki, T; Satoh, M; Sogawa, Y; Uchida, A | 1 |
| Cassis, LA; Thatcher, SE; Wang, Y | 1 |
| Chang, BI; Cheng, TL; Kuo, CH; Lai, CH; Lee, FT; Shi, GY; Wang, KC; Wu, HL; Yang, YJ | 1 |
| Chang, Z; Huang, J; Luo, C; Lv, N; Qu, Q | 1 |
| Ling, WC; Murugan, DD; Mustafa, MR; Vanhoutte, PM | 1 |
| Ait-Oufella, H; Cabuzu, D; Esposito, B; Giraud, A; Joffre, J; Kluwe, J; Lafont, A; Mallat, Z; Potteaux, S; Seguier, S; Tedgui, A; Vandestienne, M; Vilar, J; Zeboudj, L | 1 |
| Leask, A; Lipson, KE; Makino, K; Makino, T; Stawski, L; Trojanowska, M | 1 |
| Bialkowska, AB; Gao, X; Gu, X; Guo, Y; He, JC; Jain, MK; Mallipattu, SK; Mei, C; Miller, T; Pace, J; Revelo, MP; Yang, VW | 1 |
| Chen, D; Chen, J; Luo, X; Wang, Y; Wei, W; Wu, H; Xu, Z; Yan, S; Zhang, Y; Zhou, Y | 1 |
| Alawi, KM; Aubdool, AA; Baldissera, L; Brain, SD; Keeble, J; Nandi, M; Thakore, P; Wilde, E | 1 |
| Cai, W; Qiu, L; Sun, H; Zhang, Q; Zhou, Y; Zhou, Z; Zhu, X | 1 |
| Asante, S; Breeden, J; Buehler, T; Cantilena, A; Chen, L; Dawn, B; Girgis, M; Mahmoudi, SM; Samanta, A; Vincent, RJ; Xuan, YT; Zhao, L | 1 |
| Chi, C; Ge, J; Jiang, D; Li, X; Liu, H; Lu, Y; Pang, J; Peng, W; Xu, X; Xu, Y; Yan, C; Zhao, Q; Zhu, G; Zhuang, J | 1 |
| Chen, X; Duan, W; Jin, Z; Jing, L; Li, B; Li, K; Liang, H; Liu, J; Liu, Z; Reiter, RJ; Ren, K; Yang, J; Yang, Y; Yi, D; Yi, W; Yu, B; Yu, S; Zhai, M; Zhang, B; Zhang, M | 1 |
| Dechend, R; Faas, MM; Frenay, AS; Groen, H; Lely, AT; Navis, G; Toering, TJ; van der Graaf, AM; van der Wiel, MWK; Wallukat, G | 1 |
| Cunard, R | 1 |
| Choi, J; Kim, JI; Kwon, TK; Park, KM; Park, S; Sohn, SI | 1 |
| Airhart, N; Angelov, SN; Dichek, DA; Hu, JH; Shi, M; Wei, H | 1 |
| Labazi, H; Tostes, RC; Webb, RC; Wynne, BM | 2 |
| Çetin, A; Kırça, M; Oğuz, N; Yeşilkaya, A | 1 |
| Berliner, JA; Cai, L; Graham, MJ; Kim, S; Lee, RG; Lee, S; Lusis, AJ; Rateri, DL; Temel, RE; Yang, L | 1 |
| Jiang, Y; Liu, M; Peng, Y; Zhao, J; Zhou, Q; Zhou, Y | 1 |
| Gentile, O; Gonzalez, AA; Ichihara, A; Jensen, VB; Kuczeriszka, M; Mamenko, M; McDonough, AA; McLellan, M; Pochynyuk, OM; Prieto, MC; Reverte, V; Rosales, CB; Veiras, LC | 1 |
| Pallone, TL; Payne, K; Zhang, Z | 1 |
| Castillo, A; Islam, MT; Majid, DSA; Singh, P | 1 |
| Amin, HZ; Emoto, T; Fukunaga, A; Hayashi, T; Hirata, KI; Kasahara, K; Kitano, N; Matsumoto, T; Mizoguchi, T; Nishigori, C; Rikitake, Y; Sasaki, N; Tabata, T; Yamashita, T; Yodoi, K; Yoshida, N | 1 |
| Chen, Y; Fillmore, N; Gao, S; Harrington, J; Liu, P; Murphy, E; Springer, D; Stoehr, A; Wang, X; Yang, Y; Zhang, X; Zhu, J | 1 |
| Bu, J; Gao, J; Huang, C; Huang, G; Shen, W; Sun, M; Wei, T; Wu, J | 1 |
| Carvalho, V; Castro-Faria-Neto, HC; Estato, V; Freitas, F; Lessa, MA; Reis, P; Tibirica, E; Torres, R | 1 |
| Ding, G; Ma, Y; Yang, J; Yang, Q; Yang, Y | 1 |
| Aoki, H; Baba, O; Hasegawa, K; Horie, T; Ide, Y; Izuhara, M; Kimura, M; Kimura, T; Koyama, S; Kuwabara, Y; Minatoya, K; Nakao, T; Nakazeki, F; Nishi, H; Nishiga, M; Nishino, T; Ohno, S; Ono, K; Sakamoto, K; Sowa, N; Usami, S | 1 |
| Clark, MA; Haspula, D | 1 |
| Aslanidou, L; Fraga-Silva, RA; Piersigilli, A; Segers, P; Sordet-Dessimoz, J; Stampanoni, MFM; Stergiopulos, N; Trachet, B; Villanueva-Perez, P | 1 |
| Chen, Z; He, D; Jin, J; Li, H; Lu, C; Ma, X; Mao, A; Nilius, B; Pan, Q; Shen, D; Sun, C; Tang, C; Xie, M; Yang, Z; Yao, X; Zhang, P; Zhou, Y; Zhu, Y | 1 |
| Bakoyiannis, C; Damaskos, C; Georgopoulos, S; Liakakos, T; Moris, D; Patelis, N; Perrea, D; Schizas, D | 1 |
| He, B; He, W; Hu, H; Jiang, H; Liu, S; Lu, Z; Luo, D; Ma, R; Qin, Z; Xie, J; Yu, X | 1 |
| Chang, W; Li, J; Xu, N; Yuan, W; Zhang, W | 1 |
| Coselli, JS; Curci, JA; Hughes, M; Krishnamoorthy, S; LeMaire, SA; Milewicz, DM; Ren, P; Shen, YH; Wu, D; Zhang, C; Zhang, L; Zou, S | 1 |
| Amor, S; Carreño-Tarragona, G; Fernández, N; García-Villalón, AL; Granado, M; Iglesias-Cruz, MC; Martín-Carro, B; Monge, L | 1 |
| Blanco, VM; Blomkalns, AL; Cassis, LA; Chatterjee, T; Daugherty, A; Fu, X; Fulton, DJ; Gavrila, D; Hazen, SL; Huo, Y; Kim, HW; Lindower, PD; McCormick, ML; Neltner, BS; Ogbi, M; Stansfield, BK; Thomas, M; Thompson, RW; Weintraub, NL; Weiss, RM | 1 |
| Feng, Y; Huang, Y; Ji, Q; Jiang, H; Lin, Y; Liu, J; Liu, L; Liu, M; Shi, L; Shi, Y; Song, J; Wan, J; Wang, M; Wang, Z; Xu, Y; Ye, J | 1 |
| Chen, X; Cheng, YW; Jin, HY; Oudit, GY; Penninger, JM; Song, B; Wang, W; Xu, YL; Zhang, ZZ; Zhong, JC | 1 |
| Diaz-Otero, JM; Dorrance, AM; Downs, K; Fisher, C; Jackson, WF; Jaffe, IZ; Moss, ME | 1 |
| Cechova, S; Chan, F; Dong, F; Kelley, MJ; Le, TH; Ruiz, P | 1 |
| Flores-Monroy, J; Lezama-Martínez, D; Martínez-Aguilar, L; Ramirez-Hernández, D; Samano-Hernández, C; Sampieri-Cabrera, R | 1 |
| Beltz, TG; Guo, F; Johnson, AK; Xue, B | 1 |
| Angelov, SN; Dichek, DA; Zhu, J | 1 |
| Bellomo, R; Evans, RG; Kosaka, J; Lankadeva, YR; May, CN | 1 |
| Alsiraj, Y; Blalock, E; Cassis, LA; Daugherty, A; Fleenor, B; Thatcher, SE | 1 |
| Akerman, AW; Barrs, RW; Grespin, RT; Ikonomidis, JS; Jones, JA; LaRue, RAC; McDonald, LT; Mukherjee, R; Ruddy, JM; Stroud, RE | 1 |
| Greer, PA; Huang, H; Ma, WL; Shi, HZ; Song, LJ; Su, Y; Xiang, F; Xin, JB; Xiong, L; Xu, JJ; Yang, J; Ye, H; Yu, F | 1 |
| Ayme-Dietrich, E; Birling, MC; Bouabout, G; Champy, MF; Fertak, LE; Herault, Y; Jacob, H; Madeira, L; Monassier, L; Mudgett, J; Pavlovic, G; Petit-Demoulière, B; Sorg, T | 1 |
| Bounds, KR; Chatterjee, P; Gupta, S; Li, L | 1 |
| Ahmad, M; Blaustein, MP; Hamlyn, JM; Keshtkar-Jahromi, M; Leenen, FHH; Lu, J; Wang, HW | 1 |
| Aureille, J; Baron-Menguy, C; Carbone, ML; Castan, L; Chadeuf, G; Desfrançois, J; Durand, M; Goueffic, Y; Heurtebise-Chrétien, S; Loirand, G; Prieur, X; Quillard, T; Rio, M; Tesse, A; Torres, RM; Vaillant, N | 1 |
| Fan, R; Wu, X | 1 |
| Bobadilla Lugo, RA; Bracho Valdes, I; Rosas, P; Tufiño, C | 1 |
| Bleackley, RC; Bohunek, L; Bozin, T; Granville, DJ; Järvinen, TAH; McManus, BM; Merkulova, Y; Oram, C; Ruoslahti, E; Russo, V; Santacruz, S; Seidman, MA; Sellers, SL; Shen, Y; Tauh, K; Turner, C; Wu, Z; Zeglinski, MR; Zeng, H; Zhao, H | 1 |
| Blaize, AN; Chang, MS; Ejendal, KFK; Goergen, CJ; Gorman, S; Kinzer-Ursem, TL; Phillips, EH; Qureshi, HJ | 1 |
| Andrade, MA; Blackburn, MB; Holbein, WW; Toney, GM | 1 |
| Li, H; Liang, J; Liu, L; Wang, Z; Wen, Y; Zhou, P | 1 |
| Ailawadi, G; Cullen, JM; Fashandi, AZ; Hawkins, RB; Lu, G; Montgomery, WG; Salmon, MD; Spinosa, MD; Su, G; Upchurch, GR | 1 |
| Chen, WQ; Cheng, J; Ji, XP; Mao, Y; Qiao, L; Tie, YY; Xu, QB; Xu, YY; Zhai, CG; Zhang, C; Zhang, Y | 1 |
| Alajbegovic, A; Albinsson, S; Bhattachariya, A; Boettger, T; Braun, T; Dahan, D; Ekman, M; Hellstrand, P; Hien, TT; Holmberg, J; Rippe, C; Swärd, K | 1 |
| Atanasova, D; Atanassova, N; Ivanova, N; Lazarov, N; Nenchovska, Z; Pavlova, E; Tchekalarova, J | 1 |
| Chai, H; Chen, W; Chen, X; Huang, F; Su, C; Tao, Z; Xu, Y | 1 |
| Bianco, R; Brown, BA; George, SJ; Johnson, JL; Lyon, CA; Simmonds, SJ; Smith, FCT; Wadey, KS; Williams, H | 1 |
| Bukowska, A; Corradi, D; Goette, A; Hammwöhner, M; Mahardhika, W | 1 |
| Damen, FW; Goergen, CJ; Soepriatna, AH; Vlachos, PP | 1 |
| Gao, L; Li, AL; Lv, JB | 1 |
| Athayde-Filho, PF; Braga, VA; Brandão, MCR; Carlström, M; Carvalho-Galvão, A; Cruz, JC; Diniz, TF; Haworth, SM; Lemos, VS; Lundberg, JO; Montenegro, MF; Paulo, LL; Zhuge, Z | 1 |
| Bach, D; Bode, D; Doerr, R; Guthof, T; Heinzel, FR; Hohendanner, F; Jeuthe, S; Pieske, BM; Primessnig, U; Reimers, S; Wakula, P; Zhang, K | 1 |
| Hsu, YJ; Huang, PH; Liao, MT; Liao, WI; Lin, CY; Lin, SJ; Tsai, SH; Wang, JC | 1 |
| Hayashi, M; Hirokawa, F; Jin, D; Masubuchi, S; Miyaoka, Y; Ozeki, M; Takai, S; Tashiro, K; Uchiyama, K | 1 |
| Kompanowska-Jezierska, E; Kuczeriszka, M; Navar, LG; Prieto, MC; Sadowski, J | 1 |
| Buller, SA; Cooper, SG; Earley, S; Feng, Y; Jensen, DD; Li, W; Peng, H; Sigmund, CD; Sullivan, MN; Worker, CJ; Zheng, S | 1 |
| Bai, Y; Cai, L; Cui, T; Ji, H; Jiang, X; Tan, Y; Wang, Y; Wintergerst, KA; Xin, Y; Zhou, S | 1 |
| Dalman, RL; Iida, Y; Miyata, M; Xu, B; Xuan, H | 1 |
| Alzamora, R; Amador, CA; Araos, P; Cifuentes-Araneda, F; Fuentes Luppichini, E; Gonzalez, AA; Hevia, D; Michea, L; Pacheco, R; Prado, C; Rojas, M | 1 |
| Chen, HZ; Cheng, L; Hao, D; Liu, DP; Liu, Y; Pei, J; Wang, T; Xu, J; Zhang, Z; Zhao, X | 1 |
| Aoki, H; Aslanidou, L; De Backer, J; Logghe, G; Segers, P; Stampanoni, M; Stergiopulos, N; Trachet, B; Villaneuva-Perez, P | 1 |
| Chen, D; Gao, P; Huang, J; Ji, K; Li, X; Xu, T; Yan, C; Yang, Y; Zhu, D; Zuo, C | 1 |
| Lei, H; Li, J; Li, L; Liu, H; Yi, J | 1 |
| Araújo, AC; Busch, A; Caidahl, K; Di Gennaro, A; Eriksson, P; Haeggström, JZ; Jin, H; Maegdefessel, L; Samuelsson, B; Vorkapic, E; Wågsäter, D | 1 |
| Daugherty, A; Kakio, Y; Subramanian, V; Uchida, HA; Umebayashi, R; Wada, J | 1 |
| Daugherty, A; Gong, MC; Guo, Z; Hou, T; Liu, S; Lu, H; Lutshumba, J; Zhong, Y | 1 |
| Alarcon, G; Jerez, S; Medina, A; Medina, M; Peral, M; Roco, J | 1 |
| Antoku, Y; Egashira, K; Honda, K; Ichi, I; Koga, JI; Matoba, T; Nakano, K; Tsutsui, H | 1 |
| Chen, X; Li, K; Liang, K; Shi, S; Wang, G; Zhai, S; Zhang, K; Zhang, Z; Zou, G | 1 |
| Eitzman, DT; Guo, C; Kleiman, K; Sun, Y; Venugopal, J; Wang, H; Wang, J; Wang, Q | 1 |
| Gao, Y; Jiao, L; Liu, T; Shan, H; Shao, Y; Yang, B; Yin, H; Zhang, L; Zhang, Y | 1 |
| Dairou, J; Esposito, B; Haddad, Y; Mallat, Z; Metghalchi, S; Potteaux, S; Taleb, S; Tedgui, A; Vandestienne, M | 1 |
| Duan, J; Guo, J; Jou, D; Li, C; Li, S; Lin, J; Lin, L; Liu, T; Lv, J; Ma, H; Shi, W; Tao, J; Wang, Y; Yan, D; Zhai, M; Zhang, C | 1 |
| Arrellín, G; Barrita-Cruz, GJ; Castro-Martínez, G; Fragoso, G; Hernández, B; Jiménez-Ferrer, JE; Lombardo-Earl, G; Medina-Campos, ON; Méndez-Martínez, M; Pedraza-Chaverri, J; Ramírez, CC; Rosas, G; Santana, MA; Trejo-Moreno, C; Zamilpa, A | 1 |
| Bai, J; Che, YL; Li, HH; Li, J; Wang, S; Yang, XL; Yang, YZ; Zhang, YL | 1 |
| Lian, G; Wang, H; Wang, T; Xie, L; Xu, C; Zhong, H | 1 |
| E, X; Feng, Y; Gitau, SC; Li, T; Li, X; Liang, H; Liu, X; Qian, M; QiLi, M; Shan, H; Shen, Z; Wang, G; Xu, B; Zhang, Y; Zhao, D | 1 |
| Beckers, L; Daugherty, A; de Waard, V; Duijvestijn, A; Gerdes, N; Kusters, PJH; Lievens, D; Lindquist Liljeqvist, M; Lutgens, E; Newby, A; Roy, J; Seijkens, TTP; Winkels, H | 1 |
| Chen, J; Deng, P; Ding, X; Huang, X; Ren, L; Wang, K; Wang, S; Wu, C; Wu, J; Xia, J; Ye, P; Yue, Z; Zhang, A | 1 |
| Huang, M; Jia, W; Liu, X; Long, F; Qin, M; Su, Z; Suguro, R; Wu, W; Xiao, C; Yang, D; Zhu, Y | 1 |
| Abe, T; Lee Fujimoto, K; Mutsuga, M; Narita, Y; Oshima, H; Tokuda, Y; Uchida, W; Usui, A; Yamawaki-Ogata, A | 1 |
| Morishita, R; Nakagami, H | 1 |
| Liu, G; Yang, C; Yang, H; Yang, P; Yang, S; Zhao, D; Zheng, H | 1 |
| Bartolomucci, A; Beker, DL; Dyck, JRB; Grant, MK; Hamza, SM; Matsumura, N; Parajuli, N; Razzoli, M; Robertson, IM; Soltys, CM; Zordoky, BN | 1 |
| Li, D; Wang, C; Xi, Z; Xu, Z; Zhang, L | 1 |
| Baig, F; Barallobre-Barreiro, J; Barwari, T; Catibog, N; Didangelos, A; Fava, M; Jahangiri, M; Joshi, A; Lu, R; Lynch, M; Mayr, M; Mayr, U; Yin, X | 1 |
| Channon, KM; Chuaiphichai, S; Douglas, G; Gorvin, CM; Patel, J | 1 |
| Folestad, E; Länne, T; Rossignoli, A; Skogberg, J; Vorkapic, E; Wågsäter, D; Wanhainen, A | 1 |
| Coffman, TM; Gomez, RA; Gross, KW; Kurtz, A; Neubauer, B; Neubauer, K; Pan, L; Schrankl, J; Sequeira-Lopez, ML; Steppan, D; Wagner, C | 1 |
| Bäcklund, A; Boon, RA; Busch, A; Chernogubova, E; Dacken, B; Dueck, A; Eckstein, HH; Eken, SM; Engelhardt, S; Eriksson, P; Hofmann, P; Jin, H; Karlsson, J; Lao, S; Li, DY; Liu, S; Maegdefessel, L; Pelisek, J; Ramanujam, D; Roy, J; Sennblad, B; Spin, JM; Tsao, PS | 1 |
| Fujita, T; Ishigami, T; Ishikawa, Y; Kimura, K; Narikawa, M; Tamura, K; Tanaka, R; Umemura, M; Yokoyama, U | 1 |
| Kelly, M; Takei, Y; Tanaka, T; Yamanouchi, D | 1 |
| Aubdool, AA; Barrese, V; Figueiredo, HB; Greenwood, IA; Hobbs, AJ; Jepps, TA; McNeish, AJ; Stott, JB | 1 |
| Adler, GK; Jaffe, IZ; Karas, RH; Manosroi, W; Pojoga, LH; Rivera, A; Romero, JR; Seely, EW; Shukri, MZ; Tan, JW; Williams, GH; Williams, JS | 1 |
| Batlle, D; Jin, J; Liu, P; Quaggin, SE; Ramirez, V; Souma, T; Wilsbacher, LD; Wysocki, J; Ye, M; Zhou, B | 1 |
| Adelsperger, AR; Craig, BA; Goergen, CJ; Green, LA; Ibriga, HS; Murphy, MP; Phillips, EH | 1 |
| Meng, F; Tian, Z; Yan, M; Yang, P; Yang, S; Zhao, Z | 1 |
| Al-Shorbagy, MY; Ali, RM; El-Abhar, HS; Helmy, MW | 1 |
| Ho, JK; Nation, DA | 1 |
| Du, B; Gao, L; Huang, Z; Li, P; Li, Y; Liang, C; Wang, Z; Wu, L; Xiao, L; Yao, R; Zhang, D; Zhang, Y | 1 |
| Cabrini, DA; Dietrich, M; Fernandes, D; Horinouchi, CDS; Machado, W; Moreira, CG; Olchanheski, LR; Otuki, MF; Paludo, K; Pawloski, PL | 1 |
| Camelliti, P; Griffin, M; Lip, GYH; Murdoch, CE; Stuckey, DJ; Wang, Z | 1 |
| Ascaso, JF; Collado, A; Domingo, E; Escudero, P; Marques, P; Martinez-Hervás, S; Piqueras, L; Real, JT; Rius, C; Sanz, MJ | 1 |
| Czesnikiewicz-Guzik, M; Dikalov, S; Elijovich, F; Engel, N; Gnecco, JS; Guzik, TJ; Harrison, DG; Itani, HA; Jasiewicz-Honkisz, B; Laffer, CL; Laroumanie, F; Loperena, R; Maffia, P; Mikolajczyk, T; Noonan, J; Sliwa, T; Van Beusecum, JP; Weyand, CM; Xiao, L | 1 |
| Anqi, S; Baoli, Z; Biao, X; Fu, C; Jianzhou, C; Jiaxin, H; Jin, G; Jinxuan, Z; Jun, X; Lian, Z; Shuaihua, Q; Xiwen, Z; Xueling, L | 1 |
| Aghdam, S; Culp, W; Derrien-Colemyn, A; Hritzo, B; Kaur, A; Kenchegowda, D; Legesse, B; Moroni, M; Olsen, C; Severson, G | 1 |
| Divorty, N; Graham, D; Milligan, G; Nicklin, SA | 1 |
| Cambier, L; Echavez, AK; Giani, JF; Ijichi, T; Liu, W; Marbán, E; Valle, J | 1 |
| Beddhu, S; Huang, Y; Tang, L; Tian, M; Wu, Y | 1 |
| Ballabh, P; Conley, SM; Csiszar, A; Fulop, GA; Kiss, T; Martinez-Lemus, LA; Ramirez-Perez, FI; Tarantini, S; Toth, P; Ungvari, Z; Valcarcel Ares, MN; Yabluchanskiy, A | 1 |
| Brian, L; Crowley, SD; Freedman, NJ; Huang, TQ; McMahon, TJ; Miller, FJ; Nepliouev, I; Rudemiller, NP; Shenoy, SK; Stiber, JA; Wertman, V; Wu, JH; Zhang, L; Zhang, Z | 1 |
| Du, J; Hou, CL; Lai, S; Li, HH; Li, WJ; Tian, C; Wang, HX; Yang, H; Zhang, YL | 1 |
| Kashiwase, Y; Minami, K; Miyano, K; Nonaka, M; Terawaki, K; Ueta, Y; Uezono, Y; Uzu, M; Yanagihara, K; Yokoyama, T | 1 |
| Blanch, GT; Colombari, E; de Mello, ABS; Dos Santos Moreira, MC; Freiria-Oliveira, AH; Gomes, RM; Lopes, PR; Mourão, AA; Pedrino, GR; Rodrigues, KL; Xavier, CH | 1 |
| Li, H; Liu, Q; Wang, Q | 1 |
| Chuang, VTG; Hirata, S; Kadowaki, D; Kitamura, K; Maruyama, T; Miyamoto, Y; Miyamura, S; Muraya, N; Narita, Y; Otagiri, M; Taguchi, K; Uchimura, K | 1 |
| Chen, QF; Hao, H; Huang, YH; Kuang, XD; Yuan, QF; Zhang, T; Zhou, XY | 1 |
| Chen, X; Lin, Y; Luo, W; Shi, Y; Song, A; Wang, W; Zeng, Y; Zhang, Y | 1 |
| Brandt, M; Daiber, A; Foretz, M; Jansen, T; Kalinovic, S; Keaney, JF; Kröller-Schön, S; Kvandová, M; Lagrange, J; Münzel, T; Oelze, M; Schönfelder, T; Schulz, E; Steven, S; Viollet, B; Wenzel, P | 1 |
| Hitomi, H; Kitabayashi, C; Kobara, H; Kobori, H; Konishi, Y; Li, L; Masaki, T; Morikawa, T; Nakano, D; Nishiyama, A; Zhang, Y | 1 |
| Li, XC; Zhang, J; Zheng, X; Zhu, D; Zhuo, JL | 1 |
| Frank, DU; Saucerman, JJ; Sutcliffe, MD | 1 |
| Chen, L; Feng, Y; Gan, H; Haydon, RC; He, TC; Huang, B; Huang, S; Lei, J; Liu, W; Luo, W; Luu, HH; Shu, Y; Wang, X; Xia, Y; Yan, S; Yu, X; Yuan, C; Zeng, L; Zeng, Z; Zhang, B; Zhang, H; Zhang, L; Zhang, R; Zhang, X; Zhao, C | 1 |
| Channon, KM; Douglas, G; Hale, AB; Kerr, AG; Patel, J | 1 |
| Chen, YX; Sun, R; Wang, WD | 1 |
| Abraham, NG; Arad, M; Aravot, D; Cohen, K; Gorfil, D; Hochhauser, E; Kornwoski, R; Laniado-Schwartzman, M; Nudelman, V; Waldman, M; Yadin, D | 1 |
| Dampney, RA; Li, DP; Michelini, LC; Pan, HL | 1 |
| Liu, D; Nie, W; Shi, K; Xie, D; Yang, P; Yu, B; Zhang, H | 1 |
| Armstrong, B; Chen, Y; Han, X; Liu, X; Pi, M; Quarles, LD; Sun, Y; Ye, R | 1 |
| Blankesteijn, WM; Foulquier, S; Milanova, I; Namsolleck, P; Post, MJ; Prickaerts, J; Rutten, BP; Unger, T; Van Hagen, BT; Van Oostenbrugge, RJ | 1 |
| Jing, Y; Liu, S; Ni, B; Zhou, D | 1 |
| Agarwal, H; Barthwal, MK; Reddy, SS | 1 |
| Golledge, J; Kinobe, R; Krishna, SM; Morton, SK; Moxon, JV; Phie, J | 1 |
| Aires, A; Bolado, P; Cáceres, RA; Chavez, T; Cortajarena, AL; Madrazo, F; Maestro, D; Palanca, AR; Villar, AV | 1 |
| Abreu, TP; Caruso-Neves, C; Dal-Cheri, BKA; Henriques, MG; Peruchetti, DB; Pinheiro, AAS; Silva, LS; Silva-Aguiar, RP; Souza, MC; Takiya, CM | 1 |
| Cheng, T; Lin, J; Liu, Y; Wang, B; Xie, G; Yuan, Y; Zhang, L; Zheng, J | 1 |
| Cai, JH; Cheng, X; Ewurum, HC; Luo, X; Wang, M; Yang, YY; Zeng, HQ; Zeng, YM; Zhang, XB | 1 |
| Hu, G; Ito, O; Kohzuki, M; Miura, T; Muroya, Y; Ogawa, Y; Rong, R; Wang, W | 1 |
| An, WS; Jing, LS; Li, JD; Li, ZF; Mu, Y; Xu, Y; Zhao, XX | 1 |
| Chuma, M; Fujino, H; Fukushima, K; Horinouchi, Y; Ikeda, Y; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kohara, Y; Sairyo, E; Sakurada, T; Takechi, K; Tamaki, T; Tsuchiya, K; Yoshizumi, M; Zamami, Y | 1 |
| Aisicovich, M; García, SI; Landa, MS; Peres Diaz, LS; Pirola, CJ; Schuman, ML; Toblli, JE | 1 |
| Nemoto, W | 1 |
| Guan, XM; Li, J; Li, YX; Liu, JJ; Wang, HF; Wang, YW; Xin, H; Zhao, ZG | 1 |
| Lassègue, B; Ma, J; San Martín, A; Sutliff, RL; Weiss, D; Williams, HC | 1 |
| Ding, H; Huang, H; Zhou, Y | 1 |
| Arribas, SM; Diniz, C; González, MC; López de Pablo, AL; Rodríguez-Rodríguez, P; Sousa, JB; Vieira-Rocha, MS | 1 |
| Becirovic-Agic, M; Fähling, M; Hultström, M; Jönsson, S; Melville, JM; Paliege, A; Skogstrand, T | 1 |
| Alexander, MR; Bersi, MR; Chen, Y; Cox, NJ; Curci, JA; Dale, BL; Gavulic, KA; Guo, Y; Humphrey, JD; Korneva, A; Laroumanie, F; Madhur, MS; McMaster, WG; Perrien, DS; Saleh, MA; Shyr, Y; Van Beusecum, JP; Xiao, L; Zhao, S; Zhong, X | 1 |
| Li, F; Liu, Y; Luo, YX; Ren, L; Sun, Q | 1 |
| Chuma, M; Fujino, H; Fukushima, K; Goda, M; Horinouchi, Y; Ikeda, Y; Ikuto, R; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kondo, M; Murai, Y; Takechi, K; Tsuchiya, K; Zamami, Y | 1 |
| Davidson, AJ; Ferencz, SE; Grayson, JK; Hoareau, GL; Johnson, MA; Neff, LP; Russo, RM; Stewart, IJ; Williams, TK | 1 |
| Chen, Q; Nie, MX; Zhao, QM | 1 |
| Dong, H; Fang, J; Li, Y; Liu, L; Ming, S | 1 |
| Hu, Y; Liu, D; Liu, F; Liu, Z; Pan, S; Qiao, Y; Tian, F; Wang, X; Yang, Y; Zhang, Y | 1 |
| Chen, J; Hu, H; Huang, Y; Ji, Q; Jiang, H; Lin, Y; Liu, J; Liu, L; Que, B; Shi, L; Shi, Y; Wan, J; Wang, M; Wang, Y; Wang, Z; Xu, Y; Ye, D; Ye, J; Zeng, T | 1 |
| De Meyer, SF; Deckmyn, H; Desender, L; Martinod, K; Portier, I; Vandeputte, N; Vanhoorelbeke, K | 1 |
| Hou, X; Yang, S; Zheng, Y | 1 |
| Chen, N; Gao, L; Li, L; Liu, Y; Wang, X; Xiao, L; Yang, L; Zhang, J; Zhao, X | 1 |
| Brenes-Castro, D; Castillo, EC; García-Rivas, G; Torre-Amione, G; Vázquez-Garza, E | 1 |
| Gao, L; Guo, S; Liang, C; Liu, Y; Wang, X; Xiao, L | 1 |
| D'Souza, CJM; Savitha, MN; Siddesha, JM; Suvilesh, KN; Umashankar, M; Vishwanath, BS; Vivek, HK; Yariswamy, M | 1 |
| Jin, B; Shi, HM; Wen, ZC; Wu, BW; Zhu, J | 1 |
| Li, FD; Li, HH; Nie, H; Ren, HL; Tian, C; Wang, CY; Wang, HX; Zheng, YH | 1 |
| Chen, B | 1 |
| Bai, J; Li, HH; Li, J; Lin, QY; Liu, RS; Wang, S; Yu, XH; Zhang, YL | 1 |
| Fernández-Solà, J; Ferrer-Curriu, G; Garrabou, G; Guitart-Mampel, M; Mas-Stachurska, A; Planavila, A; Redondo-Angulo, I; Ruperez, C; Sitges, M; Villarroya, F | 1 |
| Avery, EG; Balogh, A; Bartolomaeus, H; Dechend, R; Eckardt, KU; Fielitz, J; Forslund, SK; Gollasch, M; Grandoch, M; Haase, N; Hering, L; Höges, S; Homann, S; Kempa, S; Kozhakhmetov, S; Kräker, K; Krannich, A; Kusche-Vihrog, K; Kushugulova, A; Maase, M; Markó, L; Müller, DN; Rump, LC; Stegbauer, J; Tsvetkov, D; Wilck, N; Wundersitz, S; Yakoub, M; Zhumadilov, Z | 1 |
| Aquino, V; Kim, S; Lobaton, GO; Oliveira, AC; Pepine, CJ; Raizada, MK; Richards, EM; Sharma, RK; Sumners, C; Yang, T | 1 |
| Huang, K; Ji, K; Lin, C; Peng, Y; Que, J; Sun, H; Wang, J; Xue, Y; Zhou, Y | 1 |
| Chen, P; Deng, Y; Feng, H; Huang, L; Ouyang, W; Wang, J; Wu, J; Xian, J; Zhu, G | 1 |
| Chinen, KT; Donato, AJ; Kronquist, EK; Lesniewski, LA; Li, DY; Reihl, KD; Walker, AE | 1 |
| Imai, Y; Ito, H; Kadowaki, A; Kuba, K; Sato, T; Suzuki, T; Watanabe, H | 1 |
| Egom, EE; Jansen, HJ; Kaur, J; Kirkby, AW; Liu, Y; Mackasey, M; Moghtadaei, M; Rafferty, SA; Rose, RA; Tuomi, JM | 1 |
| Cao, R; Qi, B; Wang, Y; Yang, W | 1 |
| Badger, SA; Bailey, MA; Bown, MJ; Butterworth, AS; Clément, M; Danesh, J; Finigan, A; Freitag, DF; Grenier, C; Harrison, J; Harrison, SC; Kullo, IJ; Lareyre, F; Lindholt, JS; Mallat, Z; Norman, PE; Paige, E; Paul, DS; Peters, JE; Powell, J; Raffort, J; Rose-John, S; Scott, DJA; Sun, BB; Sweeting, M | 1 |
| Bailey, MA; Baudrie, V; Costello, HM; Czopek, A; Dhaun, N; Farrah, T; Guyonnet, L; Kluth, DC; Lenoir, O; Menolascina, F; Moorhouse, R; Owen, E; Tharaux, PL; van Bragt, J; Webb, DJ | 1 |
| Cheng, M; Guo, X; Hu, S; Huang, C; Jiang, H; Liu, B; Wang, S; Wu, G | 1 |
| Fang, X; Gao, P; Liu, D; Lu, Z; Wang, M; Wei, X; Wu, H; Yan, Z; Yang, G; Zhang, H; Zhang, Q; Zhu, Z | 1 |
| Huang, T; Li, F; Lu, P; Sheng, Z; Wang, S; Xu, Y | 1 |
| Fu, H; Hou, FF; Li, A; Liu, Y; Tan, RJ; Xiao, L; Xu, B; Zhou, D; Zhou, L | 1 |
| Balarini, CM; Braga, VA; Carlström, M; Carvalho-Galvão, A; Cruz, JC; Guimarães, DD; Lundberg, JO; Marques, SM; Naves, LM; Pedrino, GR; Persson, AEG; Weitzberg, E; Zhuge, Z | 1 |
| Chen, X; Liu, J; Lu, W; Qiao, G; Zhai, S; Zhang, Z; Zou, G | 1 |
| Gavins, FNE; Granger, DN; Russell, J; Senchenkova, EY; Yildirim, A | 1 |
| Coffman, TM; Herrera, M; Koller, BH; Manning, MW; Sparks, MA; Yang, T | 1 |
| Abboud, FM; Chapleau, MW; Cicha, MZ; Meyerholz, DK; Nunez, S; Singh, MV | 1 |
| Abdisalaam, S; Asaithamby, A; Bhattacharya, S; Gillette, TG; Hill, JA; Lam, NT; Mukherjee, S; Nakada, Y; Nhi Nguyen, NU; Sadek, HA; Savla, JJ; Xiao, F | 1 |
| Kohan, DE; Ramkumar, N | 1 |
| Jiang, Y; Liu, R; Men, H; Shao, W; Shu, S; Zhang, W | 1 |
| Cai, L; Chen, Y; Feng, X; Han, C; Jin, L; Li, C; Li, Y; Mu, J; Yan, X; Yao, Q; Zhang, D; Zhao, R | 1 |
| Akishita, M; Endo, T; Hashizume, T; Ito, K; Nanao-Hamai, M; Noda, Y; Ogawa, S; Son, BK; Taniguchi, S | 1 |
| Li, Y; Mei, S; Qin, J; Sun, D; Yan, J; Zhang, M | 1 |
| Adams, LC; Botnar, RM; Brangsch, J; Buchholz, R; Hamm, B; Karst, U; Kaufmann, JO; Makowski, MR; Onthank, DC; Reimann, C; Robinson, SP; Thöne-Reineke, C | 1 |
| Fan, J; Li, H; Mao, H; Peng, X; Shen, J; Wang, Y; Yu, X; Zhou, Y | 1 |
| Cunningham, JT; Cunningham, RL; Farmer, GE; Marciante, AB; Nedungadi, TP; Shell, B; Snyder, B; Wang, LA | 1 |
| Agbor, LN; Davis, DR; Fang, S; Guo, DF; Hu, C; Ibeawuchi, SC; Keen, HL; Liu, X; Lu, KT; Mukohda, M; Nair, AR; Quelle, FW; Sigmund, CD; Wu, J | 1 |
| AlSiraj, Y; Cassis, LA; Chen, J; Shoemaker, R | 1 |
| Ait-Aissa, K; Castañeda, D; Gabani, M; Grumbach, I; Irani, K; Jacobs, JS; Kassan, M; Kim, YR; Koval, O; Liu, J; Trebak, M; Vikram, A | 1 |
| Cai, W; Chen, W; Chen, X; Gao, P; Li, Q; Li, X; Shen, W; Sun, L; Sun, W; Sun, Y; Wang, H; Wei, T; Xi, W; Zhou, H | 1 |
| Barhoumi, T; Berillo, O; Coelho, SC; Fraulob-Aquino, JC; Huo, KG; Mahjoub, N; Ouerd, S; Paradis, P; Richer, C; Schiffrin, EL; Sinnett, D | 1 |
| He, L; Ji, J; Tao, P | 1 |
| Gao, J; Jiang, X; Li, H; Min, Q; Ouyang, C; Qin, X; Wu, J; Yang, J; Zhang, C; Zhang, W | 1 |
| Bennett, MR; Bruneval, P; Chappell, J; Clément, M; Finigan, A; Harrison, J; Jørgensen, HF; Lareyre, F; Mallat, Z; Raffort, J; Taleb, S; Taylor, AL; Vandestienne, M | 1 |
| Haefliger, JA; Kurtz, A; Le Gal, L; Mazzolai, L; Meda, P; Pellegrin, M; Santoro, T; Wagner, C | 1 |
| Hirano, K; Igarashi, J; Karita, S; Kubota, Y; Nakai, K; Tsukamoto, I | 1 |
| Cai, H; Li, Q; Murugesan, P; Siu, KL; Youn, JY; Zhang, Y | 1 |
| Cao, C; Hasegawa, Y; Hayashi, K; Kim-Mitsuyama, S; Takemoto, Y | 1 |
| Huang, L; Khan, Z; Liang, G; Wang, J; Wang, Y; Xu, S; Xu, Z; Yu, W; Zou, C | 1 |
| Bahl, A; Dhandapany, PS; Khullar, M; Kumar, A; Mittal, A; Prasad, R; Rana, S; Raut, SK; Saikia, UN; Sarkar, S; Sharma, R | 1 |
| Agarwal, R; Azis, NA; Ismail, NH; Ismail, NM; Kamal, MSA; Radjeni, Z; Singh, HJ | 1 |
| Bin, J; Chen, Y; He, X; Lai, Y; Liao, W; Liao, Y; Song, H; Sun, Y; Wang, S; Wu, W; Yang, Y; Zhong, L | 1 |
| Lazartigues, E; Molinas, AJR; Morgan, DA; Mukerjee, S; Rahmouni, K; Xu, J; Zsombok, A | 1 |
| Akishita, M; Kojima, T; Ogawa, S; Son, BK | 1 |
| Chu, PH; Hsieh, TH; Huang, PH; Li, SY; Susztak, K; Tarng, DC | 1 |
| Beltz, TG; Felder, RB; Guo, F; Johnson, AK; Wei, SG; Xue, B; Yu, Y | 1 |
| Bedarida, T; Chen, L; Ding, Y; Lu, Q; Ma, Z; Song, P; Xie, Z; Zou, MH | 1 |
| Chen, L; Hou, I; Zhang, X | 1 |
| Becirovic-Agic, M; Hultström, M; Jönsson, S | 1 |
| Deng, W; Fan, D; Huang, SH; Ma, ZG; Tang, QZ; Wan, CX; Wang, HB; Wu, HM; Wu, QQ; Xu, M | 1 |
| Li, Y; Lou, X; Lu, Y; Nasi-Er, BG; Sun, H; Tang, B; Zhang, J; Zhang, Y; Zhou, Q; Zhou, X | 1 |
| Chen, T; Huang, W; Liang, G; Qian, J; Qian, Y; Wang, J; Wang, Z; Wu, G; You, S | 1 |
| Ahmari, N; Baekey, DM; Denson, H; Geis, NM; Khoshbouei, H; Larkin, R; Miller, DR; Raizada, MK; Redler, T; Santisteban, MM; Zubcevic, J | 1 |
| Cheema, MU; Pluznick, JL | 1 |
| Li, W; Shu, S; Wang, L; Wu, Y; Yuan, Z; Zhang, Y; Zhou, J | 1 |
| Aden, LA; Barbaro, NR; Chen, G; Ferguson, JF; Himmel, LE; Kirabo, A; Kumaresan, S; Pasic, L; Reilly, MP; Revetta, FL; Scholz, MB; Simmons, AJ; Tang, Z; Van Beusecum, JP; Warden, C; Washington, MK; Xiao, L; Zhao, S | 1 |
| Dai, WY; Hu, W; Ke, XF; Lin, HP; Liu, BW; Su, J; Xi, SS; Yang, J; Zeng, XK; Zhu, ML; Zhu, Y | 1 |
| Chan, P; Chen, X; Cheng, Y; Li, Y; Liu, J; Liu, Z; Morrisey, E; Pi, J; Reilly, M; Shen, Y; Tomlinson, B; Wang, H; Yu, Z; Zhang, L; Zhang, Q; Zhang, Y; Zheng, X; Zhuang, T | 1 |
| Gao, X; Li, S; Wang, R; Wei, Z; Xu, D; Xu, H; Yang, F; Yi, X; Zhang, B; Zhang, G; Zhang, H; Zhang, L; Zhang, X; Zhang, Y; Zhu, Y | 1 |
| Cho, S; Heo, D; Jeong, J; Lee, J; Lee, ME; Lim, S; Park, S; Seo, M; Yang, J | 1 |
| Basu, R; Bouvier, M; Couvineau, P; Fischer, C; Gerard, NP; Hazra, S; Kassiri, Z; Mix, DS; Oudit, GY; Paul, M; Penninger, JM; Poglitsch, M; Shen, M; Toth, S; Vederas, JC; Wang, F; Wang, W | 1 |
| Li, Q; Lin, L; Liu, X; Ni, Y; Qin, S; Wei, J; Zhang, C | 1 |
| Abo El Enein, A; Al Dreny, BA; Ramadan, NM; Rashed, LA; Sabry, MM | 1 |
| Cao, H; Li, HH; Wei, Y; Yin, X | 1 |
| Balogh, A; Bartolomaeus, H; Dechend, R; Forslund, SK; Henke, N; Klamer, S; Luft, FC; Markó, L; Müller, DN; Park, JK; Rong, S; Ruland, J; Wilck, N | 1 |
| Gao, XM; Xu, H; Yang, F; Zhang, BN; Zhang, GZ; Zhang, X | 1 |
| Andersen, ND; Cavanaugh, NB; Dyle, MC; Gensicke, NM; Huang, T; Qian, L; Turek, JW | 1 |
| Andia, ME; Bakewell, R; Botnar, RM; Lacerda, S; Lavin, B; Lorrio, S; Phinikaridou, A; Rashid, I; Smith, A | 1 |
| Feng, YQ; Geng, QS; Hu, ZQ; Huang, L; Huang, YQ; Shan, ZX; Yu, XJ; Zhu, JN | 1 |
| Ihm, CG; Jeong, KH; Jung, SW; Kim, DJ; Kim, DO; Kim, JS; Kim, YG; Lee, SH; Lee, SY; Lee, TW; Lee, YH; Moon, JY; Park, SH; Sohn, IS; Song, SJ | 1 |
| Liu, ZF; Pang, DW; Wang, C; Wang, J; Xu, N; Zhang, ZL | 1 |
| Cong, Z; Huang, G; Lu, Z; Qi, J; Wang, X; Xu, R; Yuan, Y | 1 |
| Du, Y; Ge, W; Han, J; Jiang, L; Xu, J; Zhang, H | 1 |
| Ahmad, S; da Silva, JS; Ferrario, CM; Groban, L; Sudo, RT; Sun, X; Varagic, J; Wang, H; Zapata-Sudo, G | 1 |
| Bautista, R; Escalante, B; Reyes-Pardo, H; Rios, A; Sánchez, D; Vargas-Robles, H | 1 |
| Fukui, A; Hara, M; Kume, O; Masaki, T; Nakada, C; Saikawa, T; Shinohara, T; Takahashi, N; Teshima, Y | 1 |
| Aderkast, C; Bukowska, A; Busch, M; Chilukoti, RK; Felix, SB; Goette, A; Homuth, G; Lendeckel, U; Mostertz, J; Völker, U; Wolke, C | 1 |
| Beltz, TG; Felder, RB; Guo, F; Johnson, AK; Wei, SG; Xue, BJ; Yu, Y; Zhang, ZH | 2 |
| Durand, MJ; Lombard, JH | 1 |
| Abe, K; Abe, S; Furusu, A; Hayashi, W; Io, K; Kohno, S; Koji, T; Miyazaki, M; Nishino, T; Obata, Y; Sugaya, T | 1 |
| Beauval, JB; de Bonnecaze, G; Doumerc, N; Game, X; Malavaud, B; Mansouri, A; Rischmann, P; Rouvellat-Terrade, P | 1 |
| Ahmad, S; Batlle, D; Brosnihan, KB; Ferrario, CM; Moniwa, N; Varagic, J; VonCannon, JL; Wysocki, J | 1 |
| Gousset, MU; Pruett, BE; Stec, DE; Storm, MV | 1 |
| de Kloet, AD; Frazier, CJ; Herman, JP; Hiller, H; Krause, EG; Pati, D; Seeley, RJ; Sumners, C; Wang, L; Woods, SC | 1 |
| Gabor, A; Leenen, FH | 2 |
| Fang, C; Lin, L; Moore, A; Wen, G; Wu, S; Xiao, Q; Ye, S; Zhang, L | 1 |
| Becker, C; Brandt, M; Daiber, A; Grabbe, S; Hausding, M; Hu, H; Karbach, SH; Knorr, M; Kossmann, S; Kröller-Schön, S; Münzel, T; Oelze, M; Schmidgen, MI; Schönfelder, T; Schwenk, M; Wenzel, P | 1 |
| Fitz, SD; Hale, MW; Hay-Schmidt, A; Johnson, PL; Lowry, CA; Sajdyk, TJ; Shekhar, A | 1 |
| Basu, R; Davidge, ST; Fan, D; Kandalam, V; Kassiri, Z; Lee, J; Morton, JS; Takawale, A; Wang, X | 1 |
| Cheng, J; Clark, J; DeGraff, LM; Langenbach, R; Loftin, CD; Myers, P; Trivedi, DB; Zeldin, DC | 1 |
| Jin, K; Kim, TH; Kim, YH; Kim, YW | 1 |
| Azushima, K; Fujita, M; Kitamura, K; Kobori, H; Maeda, A; Masuda, S; Matsuda, M; Nagahama, K; Ohsawa, M; Tamura, K; Toya, Y; Tsurumi-Ikeya, Y; Uchida, S; Umemura, S; Uneda, K; Wakui, H; Yamashita, A | 1 |
| Hirata, Y; Kitagawa, T; Kurobe, H; Matsuoka, Y; Maxfield, MW; Sata, M; Sugasawa, N | 1 |
| Jha, RK; Liu, C; Luo, X; Ma, Q; Ma, Z; Qingyuan, Z; Sha, H; Wang, Z; Wu, Z | 1 |
| Burnett, R; Charvat, TT; Dorrance, AM; Fink, GD; Penfold, ME; Rourke, JL; Seitz, B; Sinal, CJ; Sullivan, TJ; Thompson, JM; Watts, SW | 1 |
| Gu, R; Li, L; Luan, H; Wang, L; Wang, M; Wang, WH; Wu, P | 1 |
| Cowley, AW; Ilatovskaya, DV; Levchenko, V; Palygin, O; Pavlov, TS; Ryan, RP; Staruschenko, A | 1 |
| Kataoka, K; Katayama, T; Kim-Mitsuyama, S; Koibuchi, N; Maeda, M; Matsui, K; Mingjie, M; Nakagawa, T; Ogawa, H; Sueta, D; Toyama, K; Uekawa, K; Waki, H; Yasuda, O | 1 |
| Ait-Oufella, H; Bergaya, S; Bruneval, P; Caligiuri, G; Clement, M; Curis, E; Faugeroux, J; Frank, M; Hagege, A; Jeunemaitre, X; Li, W; Messas, E; Nematalla, H; Nicoletti, A; Robidel, E | 1 |
| Barreto-Chaves, ML; Bruno-Fortes, Z; Carrillo-Sepúlveda, MA; Carvalho, MH; Ceravolo, GS; Furstenau, CR; Laurindo, FR; Monteiro, Pde S; Tostes, RC; Webb, RC | 1 |
| Fukumoto, Y; Kudo, S; Liao, JK; Minami, T; Nochioka, K; Shiba, N; Shimokawa, H; Takai, Y; Tanaka, S; Williams, CL | 1 |
| Gong, X; Li, G; Li, Y; Song, Y; Yuan, L | 1 |
| Caruso-Neves, C; Costa, MF; Ferreira-Dasilva, CT; Henriques, Md; Morrot, A; Padua, TA; Pinheiro, AA; Savino, W; Silva, LS; Silva-Filho, JL; Souza, MC | 1 |
| Asanuma, K; Fukami, K; Kaida, Y; Kaifu, K; Matsui, T; Okuda, S; Takeuchi, M; Ueda, S; Yamagishi, S | 1 |
| Li, G; Li, X; Li, Z; Liu, A; Liu, Y; Su, J; Sun, L; Xu, Y; Zhu, Y | 1 |
| Bader, M; Castro Perez, A; Duarte, ID; Lima, Mde P; Pacheco, CM; Pacheco, Dda F; Pesquero, JL; Souza, Ade L | 1 |
| Babelova, A; Benkhoff, S; Brandes, RP; Fleming, I; Leisegang, MS; Loot, AE; Muntean, DM; Schröder, K; Schulz, R; Sturza, A | 1 |
| Guo, H; Hu, J; Ji, K; Jiang, F; Liao, L; Qian, L; Tang, J; Zhang, Y | 1 |
| Chiamvimonvat, N; Dong, H; Hammock, BD; Harris, TR; Imig, JD; Inoue, H; Iosif, AM; Liu, JY; Miyabe, C; Morisseau, C; Schuster, G; Ulu, A; Weiss, RH | 1 |
| Brasier, AR; Guo, DC; Ijaz, T; Ju, X; Lee, C; Lejeune, W; Milewicz, DM; Ray, S; Recinos, A; Sun, H; Tilton, RG | 1 |
| Cardoso, VN; Faraco, AA; Fernandes, RS; Fernandes, SO; Ferreira, AJ; Foureaux, G; Franca, JR; Fulgêncio, GO; Menezes, GB; Nogueira, BS; Nogueira, JC; Oliveira, GP; Raizada, MK | 1 |
| Andersen, DC; Bie, P; Eskildsen, TV; Hansen, ML; Hansen, PB; Jensen, CH; Jeppesen, PL; Marcussen, N; Nossent, AY; Rasmussen, LM; Sandberg, MB; Schneider, M; Sheikh, SP | 1 |
| Hirose, M; Ishigami, A; Kobayashi, A; Kubota, I; Misaka, T; Miyata, M; Saitoh, S; Shishido, T; Suzuki, S; Takeishi, Y | 1 |
| Nelson, C; Tang, T; Tannock, LR; Thompson, JC; Wilson, PG; Yoder, MH | 1 |
| Fujimura, T; Fujita, H; Furukawa, H; Fushida, S; Hayashi, H; Inokuchi, M; Iseki, S; Kitagawa, H; Makino, I; Miyashita, T; Nakagawara, H; Nakamura, K; Nakanuma, S; Ninomiya, I; Ohta, T; Okamoto, K; Oyama, K; Sakai, S; Shinmura, A; Tajima, H; Takamura, H; Tsukada, T; Wakayama, T | 1 |
| Auger, C; Kang, M; Kim, KR; Lee, JO; Oak, MH; Park, DH; Schini-Kerth, VB | 1 |
| Sun, L; Wang, W; Xiao, W; Yang, H | 1 |
| Ager, EI; Christophi, C; Neo, J; Wen, SW | 1 |
| He, L; He, Q; Li, C; Li, M; Li, X; Li, Y; Peng, Y; Shen, Q; Tang, Y; Wang, Y | 1 |
| Akakabe, Y; Ikeda, K; Irie, D; Kato, T; Kawahito, H; Kishida, S; Matoba, S; Matsubara, H; Mori, Y; Ogata, T; Takata, H; Ueyama, T; Wakana, N; Yamada, H | 1 |
| Chen, H; Yang, J; Zhou, CH | 1 |
| Bidani, AK; Griffin, KA; Long, J; Polichnowski, AJ; Williamson, GA | 1 |
| Gnanaselvi, SK; Gopal, K; Jahan, P; Jedy, J; Kumar, JM; Nagarajan, P; Raj, AT; Shankar, EM; Sharma, Y | 1 |
| Delafontaine, P; Galvez, S; Higashi, Y; Rezk, BM; Semprun-Prieto, L; Sukhanov, S; Tiwari, S; Yablonka-Reuveni, Z; Yoshida, T | 1 |
| Cheng, GJ; Hu, GY; Huang, L; Mei, WJ; Peng, ZZ; Qin, J; Tao, LJ; Xie, YY; Yuan, QJ; Yuan, XN | 1 |
| Cassis, LA; Chen, X; Daugherty, A; Lu, H; Tashiro, K; Zhao, M | 1 |
| Chen, M; Chen, ZW; Gao, HW; Liu, JL; Long, ZJ; Wang, YJ | 1 |
| Cao, WW; Chen, SR; Chen, X; Gao, H; Li, Q; Liu, PQ; Luo, JN; Wang, YH; Zeng, SY; Zou, J | 1 |
| Bu, L; Cheng, Z; Dong, D; Huang, T; Shen, B; Tu, Y; Wan, L; Zhao, D | 1 |
| Caliari, MV; Campagnole-Santos, MJ; Cara, DC; Cardoso, JA; Kangussu, LM; Lautner, RQ; Magalhães, GS; Marques, FD; Murari, A; Noviello, ML; Oliveira, ML; Pereira, JM; Rodrigues-Machado, MG; Santos, RA | 1 |
| Labazi, H; Tostes, R; Webb, RC; Wynne, BM | 1 |
| Chen, Q; Huang, Y; Liu, L; Pan, C; Qiu, H; Yang, Y | 1 |
| Chen, HY; Heuchel, R; Huang, XR; Lan, HY; Li, YQ; Wei, LH; Yan, BP; Yu, CM; Zhang, Y | 1 |
| Ding, W; Gu, Y; Xu, C; Zhang, M | 1 |
| Ait-Oufella, H; Bourcier, S; Dalloz, M; Esposito, B; Herbin, O; Joffre, J; Laurans, L; Loyer, X; Mallat, Z; Ponnuswamy, P; Potteaux, S; Tedgui, A; Wang, Y | 1 |
| Beyer, AM; Fredrich, K; Lombard, JH | 1 |
| Csiszar, A; Deak, F; Gautam, T; Koller, A; Mitschelen, M; Sonntag, WE; Sosnowska, D; Tarantini, S; Toth, P; Tucsek, Z; Ungvari, Z | 1 |
| Bleeker, N; de Vries, CJ; de Waard, V; Girigorie, AF; Hamers, AA; Hibender, S; Hoogenboezem, M; Marinkovic, G; Stap, J; van Broekhoven, A; van Buul, JD | 1 |
| AbdAlla, S; Fu, X; Langer, A; Quitterer, U | 1 |
| Aragon, M; Campen, MJ; Colombo, ES; Davis, J; Lucas, SN; Makvandi, M; Paffett, ML | 1 |
| Do e, Z; Fukumoto, Y; Kanazawa, M; Matsumoto, Y; Sato, A; Satoh, K; Shimizu, T; Shimokawa, H; Takahashi, K | 1 |
| Garvin, JL; Gonzalez-Vicente, A | 1 |
| Asirvatham-Jeyaraj, N; Fink, GD; King, AJ; Madan, S; Northcott, CA | 1 |
| Chhabra, KH; Lazartigues, E; Sriramula, S; Xia, H | 1 |
| Chen, YQ; Gao, YG; Gong, CS; Liu, WL; Wu, XD; Zeng, K; Zhang, CX | 1 |
| Du, Z; Gao, X; Han, H; Hang, P; Huo, R; Jiang, Y; Liu, Y; Lu, Y; Song, H; Sun, L; Wang, C; Wang, S; Wei, L | 1 |
| Higashimori, M; Ikeya, Y; Ishii, R; Kaneko, M; Komuro, I; Mano, T; Miwa, T; Ohtani, T; Omori, Y; Saito, Y; Sakata, Y; Takeda, Y; Tamaki, S; Tsukamoto, Y; Yamamoto, K | 1 |
| Bikineyeva, A; Dikalov, SI; Dikalova, AE; Griendling, KK; Harrison, DG; Hilenski, L; Lassègue, B; Nazarewicz, RR | 1 |
| Babelova, A; Brandes, RP; Mieth, A; Revermann, M; Schermuly, RT; Weigert, A | 1 |
| Chien, WM; Chin, MT; Liu, Y; Luchtel, DL; Medvedev, IO; Rosenfeld, ME; Weldy, CS | 1 |
| Asano, Y; Sato, S | 1 |
| Ayuzawa, N; Fujita, T; Ishizawa, K; Kawarazaki, W; Nagase, M; Takeuchi, M; Ueda, K; Yoshida, S | 2 |
| He, Y; Wang, W; Yang, Q | 1 |
| Miura, S; Saku, K | 1 |
| Cai, SX; Huang, S; Li, T; Li, W; Li, X; Luo, W; Meng, Y; Wu, PS; Yu, CH | 1 |
| Azuma, K; Azushima, K; Dejima, T; Kanaoka, T; Kobayashi, R; Maeda, A; Matsuda, M; Ohsawa, M; Tamura, K; Umemura, S; Uneda, K; Wakui, H; Yamashita, A | 1 |
| Balligand, JL; Beauloye, C; Belge, C; Bertrand, L; Dessy, C; Dubois-Deruy, E; Esfahani, H; Götz, KR; Hamelet, J; Hammond, J; Herijgers, P; Hilfiker-Kleiner, D; Iaccarino, G; Jnaoui, K; Langin, D; Lobysheva, I; Manoury, B; Markl, A; Nikolaev, VO; Pouleur, AC; Tavernier, G; Vanderper, A | 1 |
| Clasen, T; Fähling, M; Ishak, B; Kojda, G; Mende, S; Patzak, A; Potthoff, SA; Rump, LC; Sivritas, SH; Stamer, S; Stegbauer, J; Suvorava, T; Thieme, M | 1 |
| Hirata, Y; Ikutomi, M; Minami, Y; Morita, T; Nagai, R; Nakajima, T; Sahara, M; Sata, M | 1 |
| Hikoso, S; Murakawa, T; Nakayama, H; Nishida, K; Oka, T; Omiya, S; Otsu, K; Oyabu, J; Shah, AM; Takeda, T; Taneike, M; Ueda, H; Yamaguchi, O; Yasui, H | 1 |
| Baker, KM; Chandel, N; Kumar, R; Seqqat, R; Thomas, CM; Yong, QC | 1 |
| Buikema, H; Faas, MM; Henning, RH; Plösch, T; van Buiten, A; van der Graaf, AM; Wiegman, MJ; Zeeman, GG | 1 |
| Chang, WC; Chen, JW; Huang, PH; Leu, HB; Lin, SJ; Peng, YJ; Tsai, HY; Tsai, SH | 1 |
| Aiello, EA; Caldiz, CI; Ciancio, MC; De Giusti, VC; Orlowski, A | 1 |
| Ichikawa, I; Matsusaka, T; Niimura, F; Nishiyama, A; Pastan, I; Shintani, A | 1 |
| Bardgett, ME; Herrera-Rosales, M; Holbein, WW; Toney, GM | 1 |
| Abe, T; Aukema, HM; Horie, S; Kugita, M; Nagao, S; Nakanishi, K; Sasaki, M; Yamaguchi, T; Yoshihara, D | 1 |
| Caldiz, CI; Cingolani, HE; Correa, MV; de Cingolani, GE; Ennis, IL; Nolly, MB | 1 |
| Llinas, MT; Loria, A; Reverte, V; Salazar, F; Salazar, FJ; Tapia, A | 1 |
| Cheng, XW; Fujita, M; Inden, Y; Inoue, A; Kuzuya, M; Kyo, S; Murohara, T; Okumura, K; Shi, GP; Shimano, M; Taguchi, N; Takeshita, K; Yamamoto, T; Yoshida, N | 1 |
| Ahmadi, S; Biancardi, VC; Filosa, JA; Son, SJ; Stern, JE | 1 |
| Chen, W; Harrison, DG; Kirabo, A; Madhur, MS; Saleh, MA; Thabet, SR; Trott, DW; Wu, J; Xiao, L | 1 |
| Du, J; Li, FD; Li, HH; Ren, HL; Tian, C; Zheng, YH | 1 |
| Beierwaltes, WH; Cabral, PD; Garvin, JL; Hong, NJ; Hye Khan, MA; Imig, JD; Ortiz, PA | 1 |
| Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; McKie, PM; Sangaralingham, SJ | 1 |
| Chen, K; Chen, Y; Fan, GC; Gao, L; Gong, H; Jiang, DS; Li, H; Liu, PP; Liu, Y; Peng, J; Yang, Q; Zhang, XD; Zhang, XF; Zhang, Y; Zhou, H; Zou, Y | 1 |
| Blumer, KJ; Dietrich, HH; Knutsen, RH; Kozel, BA; Mecham, RP; Osei-Owusu, P | 1 |
| Cui, L; Liu, R; Qi, H; Wang, J; Wang, Y; Wen, Y; Yin, C | 2 |
| Du, J; Li, Y; Wang, C; Wu, Y; Zhang, C | 1 |
| Chen, Y; Liu, C; Liu, H; Meng, W; Sun, Y; Zhao, T; Zhao, W | 1 |
| Cassis, LA; Daugherty, A; Thatcher, S; Wu, C; Zhang, X | 1 |
| Batlle, D; Haber, PK; Haque, SK; Maier, C; Wysocki, J; Ye, M | 1 |
| Huang, F; Huang, H; Liu, Y; Tang, W; Wang, J; Wang, MH; Wang, T; Zhang, H; Zhang, K; Zhu, X | 1 |
| Chen, XJ; Du, XN; Si, M; Wang, C; Xu, JX; Zhang, HL; Zhang, HR; Zhang, XD | 1 |
| Alzamora, R; Ayala, P; Barrientos, V; Chiong, M; Díaz-Araya, G; Escudero, N; García, L; Godoy, I; Hevia, D; Jalil, JE; Lavandero, S; Michea, L; Morales, C; Moya, J; Novoa, U; Ocaranza, MP; Pinto, M | 1 |
| Alghamri, MS; Elased, KM; Grobe, N; Meszaros, JG; Morris, M | 1 |
| Barish, GD; Kim, J; Tangirala, RK; Tietge, UJ; van Stijn, CM | 1 |
| Golledge, J; Krishna, SM; Liu, D; Moran, CS; Seto, SW | 1 |
| Burger, D; Chibale, K; Mahajan, A; Reudelhuber, TL; Sturrock, ED; Touyz, RM | 1 |
| de Kloet, AD; Hiller, H; Nguyen, D; Pioquinto, DJ; Smith, JA; Sumners, C; Wang, L | 1 |
| Chen, HY; Feng, M; Huang, XR; Lan, HY; Li, YQ; Liu, GX; Meng, XM; Shi, YJ; Wei, LH; Zhang, Y | 1 |
| Aoki, H; Aonuma, K; Furusho, A; Hamano, K; Hirakata, S; Hiroe, M; Ikeda, Y; Imaizumi, T; Imanaka-Yoshida, K; Ito, S; Kimura, T; Matsuzaki, M; Miyamoto, T; Nishida, N; Shiraishi, K; Ueno, T; Yoshida, T; Yoshimura, K | 1 |
| Brain, SD; de Winter, P; Dessapt-Baradez, C; Fernandes, E; Gnudi, L; Heads, RJ; King, R; Kodji, X; Marshall, N; Outzen, E; Pozsgai, G; Sams, A; Shah, AM; Siow, RC; Smillie, SJ | 1 |
| Chunsheng, W; Hu, S; Jianqiang, K; Jingjing, Z; Kunzheng, W; Ruiyu, L; Yongtao, Z | 1 |
| Bi, X; Fu, G; Han, J; Li, Z; Shen, X; Song, J; Wang, M; Ye, Y; Zhang, J | 1 |
| Li, PF; Liu, CY; Liu, F; Long, B; Sun, T; Wang, K; Wang, Y; Yuan, SM; Zhang, XJ; Zhou, LY | 1 |
| Chung, AC; Huang, XR; Lan, HY; Wei, LH; Yu, CM; Zhang, Y | 1 |
| Cui, W; Fu, J; Maimaitiyiming, H; Norman, H; Qi, X; Wang, S; Wang, X; Zhou, Q | 1 |
| Bódi, N; Kovacs, G; Nyengaard, JR; Razga, Z; Talapka, P | 1 |
| Chen, G; He, QY; Pan, SF; Pan, SQ; Shen, C; Zhang, XM | 1 |
| Fürst, DO; Gonzalez-Carmona, MA; Görtzen, J; Granzow, M; Huss, S; Klein, S; Knolle, P; Kowallick, B; Krämer, B; Laleman, W; Linhart, M; Mazar, IG; Nattermann, J; Sauerbruch, T; Schierwagen, R; Schildberg, FA; Shah, VH; Siegmund, SV; Trebicka, J; Vogt, A; Werner, N; Wojtalla, A | 1 |
| Chen, Y; Iwaya, S; Oikawa, M; Takeishi, Y | 1 |
| Harris, RA; Sullivan, JC; Zimmerman, MA | 1 |
| Bailey, M; Bellomo, R; Burrell, LM; Calzavacca, P; May, CN; Ramchandra, R; Velkoska, E | 1 |
| Beltz, T; Clayton, SC; Johnson, AK; Xue, B; Zhang, Z | 1 |
| Ai, D; Hammock, BD; Li, L; Li, N; Pang, W; Zhang, X; Zhu, Y | 1 |
| Fan, YY; Li, N; Li, PF; Liu, CY; Liu, F; Long, B; Murtaza, I; Wang, K; Zhou, QY | 1 |
| Cheng, C; Huang, H; Huang, J; Liu, B; Liu, S; Pan, W; Sun, W; Xiong, L; Ye, J; You, X; Zhong, Y | 1 |
| Kohan, DE; Li, C; Lu, X; Peng, K; Wang, F; Wang, W; Yang, T; Yu, X; Zhou, L; Zhu, SF | 1 |
| Anand-Srivastava, MB; Atef, ME | 1 |
| Corrêa, TD; Djafarzadeh, S; Jakob, SM; Jeger, V; Pereira, AJ; Takala, J | 1 |
| He, H; He, J; He, L; Song, J; Wang, T; Zhou, N | 1 |
| Bendall, JK; Channon, KM; Choudhury, RP; Crabtree, MJ; Douglas, G; Fan, LM; Hale, AB; Li, JM; Mai, A; McAteer, MA; McNeill, E; Schneider, JE | 1 |
| Arita-Okubo, S; Itabe, H; Kim-Kaneyama, JR; Lei, XF; Miyazaki, A; Miyazaki, T; Offermanns, S | 1 |
| Griendling, KK; Jang, IH; Jo, H; Kim, CW; Kumar, S; Son, DJ | 1 |
| Inoue, T; Ishii, N; Miyazaki, T; Nishiyama, A; Ohno, Y; Suzuki, H; Takenaka, T | 1 |
| Cheng, W; Ge, J; Hou, Y; Hu, J; Li, Y; Lv, P; Niu, C; Wang, F; Yan, Y; Yang, Z | 1 |
| Charles, RL; Eaton, P; Freeman, BA; Hammock, BD; Kamynina, A; Morisseau, C; Prysyazhna, O; Rudyk, O; Yang, J | 1 |
| Entman, ML; Jin, X; Wang, Y; Xia, Y; Yan, J | 1 |
| Chinnathambi, V; Hankins, GD; More, AS; Sathishkumar, K; Yallampalli, C | 1 |
| Beltz, TG; Guo, F; Hay, M; Johnson, AK; Xue, B; Zhang, Z | 2 |
| Fairfax, ST; Mauban, JR; Rizzo, MA; Wier, WG; Zhang, J | 1 |
| Cavasin, MA; Chen, B; Demos-Davies, KM; Ferguson, BS; Ferrara, C; Horn, TR; Jeong, MY; Mahaffey, JH; McKinsey, TA; Piroddi, N; Poggesi, C; Scellini, B; Schuetze, KB; Spiltoir, JI; Tesi, C; Williams, SM | 1 |
| Bai, H; Ben, J; Chen, Q; Fang, R; Li, X; Qian, L; Wang, Z; Xu, Y; Yang, Q; Zhang, H; Zhu, X | 1 |
| Acuña, S; Corthorn, J; Ortíz, R; Padilla, O; Schneider, D; Valdés, G | 1 |
| Dong, W; Gong, G; Lin, X; Wang, X; Yang, B; Yang, Y; Yuan, B | 1 |
| Chen, J; Deng, Y; Guo, D; Jiang, B; Li, D; Liu, X; Ma, H; Shen, X; Teng, F; Wu, W; Xu, F; Xu, J; Yang, M; Zhang, G; Zhang, L; Zhang, T; Zhang, Z | 1 |
| Dunn, SE; Hay, M; Ji, H; Li, X; Liu, J; Sandberg, K; Speth, RC; Umans, JG; Wu, X; Zhang, MA; Zheng, W | 1 |
| Bader, M; Brosnihan, KB; Dechend, R; Howlett, AC; McGee, CM; Pulgar, VM; Varagic, J; Yamaleyeva, LM | 1 |
| Guo, J; Huo, ZJ; Ji, XL; Li, FY; Liu, C; Peng, B; Shen, HB; Zhang, L | 1 |
| de Boer, RA; Frenay, AR; Hillebrands, JL; Leuvenink, HG; Pasch, A; Snijder, PM; van Goor, H | 1 |
| Bonev, AD; Dalsgaard, T; Hill-Eubanks, DC; Kotlikoff, MI; Nelson, MT; Santana, LF; Scott, JD; Sonkusare, SK | 1 |
| Balakrishnan, A; Cassis, LA; Charnigo, R; Daugherty, A; Davis, FM; Howatt, DA; Moorleghen, JJ; O'Connor, WN; Rateri, DL | 1 |
| Dai, Z; He, H; Huang, C; Meng, Y; Tang, Y; Wang, X; Xiao, J; Yu, S; Zhao, Q | 1 |
| Caluwé, E; Dymarkowski, S; Herijgers, P; Hermans, H; Herregods, MC; Janssens, S; Pokreisz, P; Swinnen, M | 1 |
| Bavaria, JE; Branchetti, E; Ferrari, G; Gorman, JH; Gorman, RC; Grau, JB; Lai, EK; Poggio, P; Sacks, MS | 1 |
| Cardin, S; Deschepper, CF; Jeidane, S; Picard, S; Praktiknjo, S; Reudelhuber, TL; Scott-Boyer, MP | 1 |
| Korbmacher, C; Loffing, J; Loffing-Cueni, D; Makhanova, N; Mihailova, M; Nesterov, V; Picard, N; Sorensen, MV; Todkar, A; Wagner, CA | 1 |
| Chandrashekar, K; Juncos, LA; Lai, EY; Liu, R; Lu, Y; Shen, C; Song, J; Wang, L; Wang, S; Wei, J | 1 |
| Al-Magableh, MR; Hart, JL; Kemp-Harper, BK | 1 |
| Arévalo, M; Docherty, NG; Eleno, N; Fuentes-Calvo, I; Grande, MT; López-Novoa, JM; Pérez-Barriocanal, F; Rodríguez-Peña, AB | 1 |
| Chen, Y; Gu, W; Lin, ZC; Lu, Y; Ma, WG; Meng, FX; Shang, XZ; Tan, L; Wang, YN; Xu, YM | 1 |
| Jo, H; Jung, SH; Kang, KD; Lee, SJ; Yim, HB | 1 |
| Apel, IJ; Balogh, A; Binger, KJ; Choi, M; Dechend, R; Fokuhl, V; Haase, N; Henke, N; Heuser, A; Lucas, PC; Luft, FC; Markó, L; McAllister-Lucas, LM; Müller, DN; Oravecz-Wilson, KI; Park, JK; Przybyl, L; Qadri, F; Ruland, J; Spallek, B; Wilck, N | 1 |
| Crowley, SD; Griffiths, R; Jin, H; Karlovich, NS; Lin, EE; Mao, A; Patel, MB; Song, YS; Sparks, MA; Wu, M; Zhang, J | 1 |
| Kigawa, Y; Kim-Kaneyama, JR; Lei, XF; Miyazaki, A; Miyazaki, T; Nakamachi, T; Oguchi, T; Shioda, S; Taniyama, M; Tsunawaki, S | 1 |
| Bíbová, J; Červenka, L; Hampl, V; Herget, J; Husková, Z; Jíchová, Š; Kramer, HJ; Sadowski, J; Vaňourková, Z | 1 |
| Baňasová, A; Bíbová, J; Červenka, L; Hampl, V; Herget, J; Husková, Z; Jíchová, Š; Kujal, P; Sadowski, J; Vaňourková, Z; Vernerová, Z | 1 |
| Chen, S; Gardner, DG; Glenn, DJ; Ng, M; Ni, W; Watts, SW | 1 |
| Almoghrabi, A; Bissonnette, M; Dougherty, U; Hart, J; Joseph, L; Karczmar, GS; Khare, S; Konda, VJ; Kreisheh, M; Li, YC; Liu, W; Mustafi, D; Mustafi, R; Pekow, J; Sadiq, F; Sundaramurthy, S; Wyrwicz, A | 1 |
| Albuquerque, DM; Almeida, CB; Brugnerotto, AF; Conran, N; Costa, FF; dos Santos, AF; Franco-Penteado, CF; Lanaro, C; Leonardo, FC; Pallis, FR; Roversi, FM | 1 |
| Chen, Y; Lu, G; Lu, Z; Song, F | 1 |
| Deshotels, MR; Filipeanu, CM; Lazartigues, E; Sriramula, S; Xia, H | 1 |
| Li, F; Liao, Y; Liu, J; Wang, Y; Wei, Z; Wu, J; Yao, Y; Ye, P; Zhang, K; Zhou, Y | 1 |
| Csiszar, A; Gautam, T; Koller, A; Mitschelen, M; Sonntag, WE; Sosnowska, D; Tarantini, S; Toth, P; Tucsek, Z; Ungvari, Z | 1 |
| Arendshorst, WJ; Chen, W; Goldstein, A; Harrison, DG; Itani, H; Kirabo, A; Li, CI; Madhur, MS; Norlander, AE; Saleh, MA; Shyr, Y; Thabet, SR; Trott, DW; Wu, J | 1 |
| Bassi, M; da Silva, AA; do Carmo, JM; Dubinion, JH; Hall, JE; Hamza, SM; Mokhtarpouriani, K | 1 |
| Cai, S; Chen, Q; He, H; Liu, A; Liu, L; Lu, X; Qiu, H; Yang, Y | 1 |
| Abrigo, J; Brandan, E; Cabello-Verrugio, C; Meneses, C; Morales, MG; Simon, F | 1 |
| Guo, RW; Kuang, CW; Liu, B; Xi, YY; Yang, LX | 1 |
| Baylis, C; Cunningham, MW; Sasser, JM | 1 |
| Cassis, LA; Curci, JA; Daugherty, A; Ennis, T; Gurley, SB; Howatt, DA; Thatcher, SE; Yiannikouris, F; Zhang, X | 1 |
| Biros, E; Golledge, J; Jose, RJ; Moran, CS | 1 |
| Desland, FA; Grobe, JL; Liu, M; Raizada, MK; Shan, Z; Shen, XZ; Shi, P; Sumners, C; Zhou, G | 1 |
| Ailawadi, G; Bhamidipati, CM; Hajzus, VA; Meher, AK; Mehta, GS; Owens, GK; Salmon, M; Su, G; Upchurch, GR; Whatling, CA | 1 |
| Duan, XC; Fang, ZH; Gao, JR; Wang, YZ; Wu, J; Xia, LZ; Yao, XM | 1 |
| Cheng, J; Garg, V; Hans, CP; Koenig, SN; Kuivaniemi, HS | 1 |
| Chu, D; Deng, Z; Du, D; Gao, L; Li, S; Lou, J; Lou, X; Xie, G; Zhou, Y; Zhu, T | 1 |
| Cui, W; Liu, J; Sun, X; Xie, X; Zhang, D; Zhu, Y | 1 |
| Du, J; Han, QY; Jiang, X; Li, HH; Liu, Y; Miao, J; Song, L; Tian, C; Wang, AW; Wang, HX; Xia, YL; Yu, L | 1 |
| Aoki, H; Karasawa, T; Kawashima, A; Kimura, H; Noda, T; Sagara, J; Shirasuna, K; Takahashi, M; Taniguchi, S; Tatsumi, K; Tsutsui, H; Usui, F; Yoshimura, K | 1 |
| Cui, J; Du, Y; He, J; Li, J; Ma, Y; Zhang, X | 1 |
| Balakrishnan, A; Cassis, LA; Daugherty, A; Davis, FM; Fornwalt, BK; Haggerty, CM; Howatt, DA; Muratoglu, SC; Rateri, DL; Strickland, DK | 1 |
| Gao, S; Guo, K; Huang, LL; Pan, C; Wang, HZ; Wang, XH; Yu, TT; Zhang, JY | 1 |
| Beeri, R; Berlatzky, Y; Bulut, A; Gavish, L; Gavish, LY; Gertz, SD; Gilon, D; Reissman, P; Rubinstein, C | 1 |
| Azhar, A; El-Bassossy, HM | 1 |
| Choi, YW; Kim, CD; Lee, SJ; Park, SY; Ye, BH | 1 |
| Chen, D; Chen, Q; Cheng, X; Fang, M; Gao, Y; Li, L; Liang, P; Weng, X; Wu, X; Xu, H; Xu, Y; Yang, Y; Yu, L; Zhang, T; Zhou, B | 1 |
| Chen, C; Harris, D; Li, S; Liang, Y; Patel, O; Qin, Z | 1 |
| Dadlez, M; Drapala, A; Jazwiec, R; Sikora, M; Skrzypecki, J; Ufnal, M | 1 |
| Liu, P; Liu, Z; Tian, K; Wang, J; Xu, S; You, T | 1 |
| Bidani, AK; Griffin, KA; Licea-Vargas, H; Long, J; Picken, MM; Polichnowski, AJ; Williamson, GA | 1 |
| Bruce, E; Espejo, A; Francis, J; Horowitz, A; Katovich, MJ; Nair, A; Oswalt, A; Raizada, MK; Rathinasabapathy, A; Shenoy, V; Steckelings, UM; Sumners, C; Unger, T | 1 |
| Biros, E; Clancy, P; Golledge, J; Jose, RJ; Krishna, SM; Moran, CS; Seto, SW; Wang, Y | 1 |
| Ait-Oufella, H; Esposito, B; Loyer, X; Mallat, Z; Mellak, S; Poirier, M; Potteaux, S; Tedder, TF; Tedgui, A | 1 |
| Jo, CH; Simoni, J; Wesson, DE | 1 |
| Choi, E; Daugherty, A; Eguchi, S; Elliott, KJ; Forrester, SJ; Fukuda, Y; Kawai, T; Kobayashi, T; Obama, T; Rizzo, V; Takayanagi, T; Taro, Y; Tsuji, T | 1 |
| Astolfo, A; Fraga-Silva, RA; Modregger, P; Piersigilli, A; Segers, P; Sordet-Dessimoz, J; Stampanoni, MF; Stergiopulos, N; Tedgui, A; Trachet, B; Van der Donckt, C | 1 |
| Aoki, Y; Imaizumi, T; Kai, H; Kudo, H; Takayama, N; Yasuoka, S | 1 |
| de Roo, M; Golestani, R; Hilgerink, K; Jung, JJ; Liu, C; Nie, L; Razavian, M; Robinson, SP; Sadeghi, MM; Ye, Y; Zhang, J | 1 |
| Brzozowski, B; Brzozowski, T; Konturek, SJ; Krzysiek-Maczka, G; Kwiecien, S; Pajdo, R; Pawlik, MW; Ptak-Belowska, A; Strzalka, M | 1 |
| Anzai, A; Endo, J; Fukuda, K; Ito, K; Katsumata, Y; Kohno, T; Matsuhashi, T; Okada, Y; Sano, M; Shimizu-Hirota, R; Shimoda, M; Shinmura, K; Shirakawa, K; Ueha, S; Yamada, Y; Yamamoto, T; Yan, X | 1 |
| Fu, S; Lu, Z; Shi, H; Xiao, Y; Ye, W; Zhang, Y | 1 |
| Ahn, JS; Jeon, BH; Kim, HS; Kim, I; Kim, IK; Kim, ST; Koh, GY; Lee, S; Song, S; Woo, DC | 1 |
| Emoto, T; Hirata, K; Kasahara, K; Kita, T; Matsumoto, T; Mizoguchi, T; Sasaki, N; Sasaki, Y; Sparwasser, T; Yamashita, T; Yodoi, K | 1 |
| Delpire, E; Harrison, DG; Kamat, NV; Kirabo, A; Madhur, MS; McDonough, AA; Saleh, MA; Thabet, SR; Xiao, L | 1 |
| Ago, T; Kamouchi, M; Kitazono, T; Kuroda, J; Matsuo, R; Nakamura, K; Nishimura, A; Wakisaka, Y | 1 |
| Dang, MQ; Lai, S; Li, HH; Liu, Y; Wang, L; Wang, X; Xia, YL; Yu, XH; Zhang, YL; Zhao, XC | 1 |
| Bian, Y; Cao, Y; Ding, L; Dou, L; Li, J; Lin, Y; Lu, Y; Man, Y; Qin, W; Ruan, Y; Shen, T; Wang, S; Xi, C; Xiao, C; Zhu, Y | 1 |
| Chen, C; He, Z; Hoopes, SL; Wang, DW; Wen, Z; Zeldin, DC; Zhang, X | 1 |
| Berger, JM; Brégeon, J; Calderon, C; Cariou, B; Hadchouel, J; Le May, C; Loirand, G; Prieur, X; Vaillant, N | 1 |
| Escudero, P; Ferrando, C; Furio, E; Gonzalez-Navarro, H; Juez, M; Navarro, A; Piqueras, L; Sanz, MJ | 1 |
| Basu, R; Fan, D; Kassiri, Z; Lee, J; Sakamuri, SS; Shen, M; Wang, X | 1 |
| Bloch, S; Girouard, H; Obari, D | 1 |
| Li, J; Li, M; Liu, X; Meng, G | 1 |
| Bonventre, JV; Estes, AM; Fang, XR; Jennings, BL; Khan, NS; Malik, KU; Song, CY | 1 |
| Rice, AS; Smith, MT | 1 |
| Ichikawa, I; Matsusaka, T; Miyazaki, Y; Niimura, F; Nishiyama, A; Okabe, M; Pastan, I; Yokoo, T | 1 |
| Arditi, M; Cercek, B; Chen, S; Chyu, KY; Dimayuga, PC; Honjo, T; Lio, WM; Shah, PK; Trinidad, P; Yano, J; Zhao, X; Zhou, J | 1 |
| Afroze, SH; Dostal, D; Gergely, M; Glaser, S; Guerrier, M; Martínez, AK; Munshi, MK; Nizamutdinov, D; Szynkarski, C; Uddin, M | 1 |
| Chai, M; Dong, Z; Ji, Q; Lin, Y; Liu, Y; Lu, Q; Meng, K; Wu, B; Yu, K; Zeng, Q; Zhang, J; Zhou, Y | 1 |
| A, LT; Bai, Q; Liang, YX; Wang, Y; Wu, HY; Zheng, DX; Zhuang, Z | 1 |
| Balakrishnan, A; Cassis, LA; Daugherty, A; Howatt, DA; Lu, H; Moorleghen, JJ; Vander Kooi, CW; Wang, JA; Wu, C; Xu, Y | 1 |
| Estes, AM; Fang, XR; Gonzalez, FJ; Jennings, BL; Kanu, A; Malik, KU; Moore, JA; Pingili, AK | 1 |
| Machado, SS; Marques, ME; Pereira, HJ; Tenório, Hde A | 1 |
| Esmaeli-Mahani, S; Masoomi, Y; Najafipour, H; Shahouzehi, B; Soltani Hekmat, A; Vakili, A; Yeganeh Hajahmadi, M | 1 |
| Chen, Q; Dai, X; Fang, M; Li, L; Liang, P; Weng, X; Wu, X; Xu, H; Xu, Y; Yu, L; Zhou, B | 1 |
| Chen, X; Dong, B; Dong, XF; Hao, QQ; Li, SY; Tengbeh, AF; Yu, QT; Zhang, Y; Zhang, YH; Zhou, XM | 1 |
| Baumbach, GL; Chan, SL; Umesalma, S | 1 |
| Huai, R; Li, C; Qu, Z; Wang, B | 1 |
| Che, W; Guo, H; Hou, L; Jie, Q; Li, G; Liu, B; The, E; Wang, D; Wei, Y | 1 |
| Bailey, W; Balakrishnan, A; Charnigo, RJ; Daugherty, A; De Beer, FC; De Beer, MC; Howatt, DA; Ji, A; Noffsinger, VP; Rateri, DL; Shridas, P; Webb, NR; Witta, J; Wroblewski, JM | 1 |
| Cordopatis, P; Inui, M; Ishiguro, S; Kawabata, A; Magafa, V; Oka, M; Takao, S; Tamura, M; Tsunedomi, R; Tzakos, AG; Wall, T; Yoshimura, K | 1 |
| Del Valle-Mondragón, L; Guzmán-Hernández, EA; Ibarra-Barajas, M; Pastelín-Hernández, G; Sánchez-Mendoza, MA; Villalobos-Molina, R | 1 |
| Andrés, V; Blanco-Colio, LM; Burillo, E; Calvo, E; Egido, J; Esteban, M; Jorge, I; Laustsen, J; Lindholt, JS; Lopez, JA; Martin-Ventura, JL; Martinez-Pinna, R; Meilhac, O; Michel, JB; Molina-Sánchez, P; Ramos-Mozo, P; Tarin, C; Torres-Fonseca, MM; Vazquéz, J; Vega de Ceniga, M | 1 |
| Azushima, K; Dejima, T; Fujikawa, T; Haruhara, K; Kanaoka, T; Kobayashi, R; Matsuda, M; Nishiyama, A; Ohki, K; Ohsawa, M; Tamura, K; Tsurumi-Ikeya, Y; Umemura, S; Uneda, K; Wakui, H; Yabana, M; Yamashita, A | 1 |
| Chelakkot-Govindalayathil, AL; D'Alessandro-Gabazza, CN; Gabazza, EC; Harada, E; Morizono, T; Roeen, Z; Sumiya, T; Toda, M; Urawa, M; Yano, Y; Yasuma, T | 1 |
| Baylis, C; Cunningham, MW; Deng, A; Wen, X; West, CA | 1 |
| Chen, Q; Fan, Z; Fang, M; Ji, Y; Li, J; Li, L; Li, Y; Liang, P; Tian, W; Weng, X; Wu, X; Xu, H; Xu, Y; Yang, G; Yu, L | 1 |
| Bols, J; Degroote, J; Segers, P; Stergiopulos, N; Trachet, B; Verhegghe, B; Vierendeels, J | 1 |
| Li, YL; Liu, J; Muelleman, RL; Tu, H; Zhang, D; Zheng, H | 1 |
| Chapp, AD; Chen, QH; Gui, L; Huber, MJ; LaGrange, LP; Larson, RA; Shan, Z; Zhu, J | 1 |
| Chen, TT; Guo, YH; Li, JJ; Liu, YL; Shi, K; Wang, XM; Yang, S; Yang, YF | 1 |
| Estes, AM; Gonzalez, FJ; Kara, M; Khan, NS; Li, W; Lin, Z; Malik, KU; Pingili, AK | 1 |
| Ikeda, H; Kitazono, T; Noguchi, H; Suehiro, T; Tokumoto, M; Toyonaga, J; Tsuruya, K; Yamada, S | 1 |
| Fan, Y; Hu, L; Li, QP; Liu, C; Song, YC; Wang, Y; Zhou, L; Zhu, HY | 1 |
| Chen, BH; Courchesne, P; Harrison, DG; Huan, T; Joehanes, R; Johnson, AD; Levy, D; Liu, P; Madhur, MS; Meng, Q; Munson, PJ; Norlander, AE; O'Donnell, CJ; Raghavachari, N; Saleh, MA; Vasan, R; Wang, R; Yang, X; Ying, S; Zhang, B; Zhu, J | 1 |
| Chen, FK; Chen, XP; Guo, HY; Li, J; Li, YG; Liang, Z; Lin, K; Liu, LF; Shan, ZL; Shi, XM; Wang, YT | 1 |
| He, C; Li, P; Su, H; Tian, K; Wan, JB; Zhang, XJ | 1 |
| Andrés, V; Díez, J; González-Gómez, C; Guzmán-Martínez, G; Maraver, A; Orbe, J; Rivera-Torres, J; Serrano, M; Villa-Bellosta, R | 1 |
| Davisson, RL; Eguchi, S; Elliott, KJ; Forrester, SJ; Fukuda, Y; Kawai, T; Obama, T; Park, JY; Takayanagi, T; Tilley, DG; Tsuji, T | 1 |
| Anrather, J; Faraco, G; Iadecola, C; Luo, W; Park, L; Paul, SM; Zhou, P | 1 |
| Cheng, G; Chu, Y; Dooley, SA; Gu, H; Hasan, D; Heistad, DD; Pena Silva, RA; Pierce, GL; Wegman-Points, L; Wilson, K | 1 |
| Bernstein, KE; Capdevila, JH; Dakarapu, R; Ding, Y; Falck, JR; Garcia, V; Gotlinger, K; Joseph, G; Schwartzman, ML; Shkolnik, B; Zhang, FF | 1 |
| Annis, DS; Liu, B; Liu, Z; Morgan, S; Mosher, DF; Ren, J; Sheibani, N; Sorenson, CM; Wang, Q; Zhang, J | 1 |
| Bali, A; Jaggi, AS | 1 |
| Bennion, DM; Donnangelo, LL; Haltigan, EA; Irwin, AJ; Pioquinto, DJ; Purich, DL; Regenhardt, RW; Sumners, C | 1 |
| Ardell, JL; Hardwick, JC; Powers, EN; Ryan, SE; Southerland, EM | 1 |
| Feng, Y; Hammond, SL; Li, W; Liu, J; Saifudeen, Z; Tjalkens, RB | 1 |
| Alexander, IE; Angus, PW; Chin, R; Cunningham, SC; Habib, MR; Herath, CB; Mak, KY; Sharland, AF; Torresi, J | 1 |
| Deng, KQ; Gao, L; Jiang, DS; Jiang, X; Li, H; Luo, Y; Zhang, P; Zhang, XF; Zhao, GN; Zhu, X | 1 |
| Balakrishnan, A; Cassis, LA; Daugherty, A; Howatt, DA; Liu, J; Lu, H; Moorleghen, JJ; Sorci-Thomas, M | 1 |
| Bürgelová, M; Červenka, L; Hammock, BD; Husková, Z; Hwang, SH; Imig, JD; Melenovský, V; Sadowski, J; Škaroupková, P; Sporková, A | 1 |
| Bernstein, KE; Li, L; Li, Y; Lyden, P; Shah, KH; Shen, XZ; Shi, P | 1 |
| Ask, K; Carlisle, RE; Cruz, GL; Dickhout, JG; Lu, C; Mohammed-Ali, Z; Werner, KE | 1 |
| Cheng, JX; Goergen, CJ; Phillips, EH; Schroeder, HD; Wilson, KE; Yrineo, AA | 1 |
| He, M; Wen, JK; Yang, Z; Yue, LY; Zhang, M; Zhang, RN; Zhang, W; Zhang, X; Zhang, XH; Zheng, B | 1 |
| Al-Omran, M; Dhingra, N; Leong-Poi, H; Lovren, F; Quan, A; Ramadan, A; Singh, KK; Teoh, H; Verma, S; Wheatcroft, MD | 1 |
| Azegami, T; Hayashi, K; Itoh, H; Nakamura, M; Oguchi, H; Sakamaki, Y; Sasamura, H; Tokuyama, H; Wakino, S | 1 |
| Hayashi, H; Jiang, D; Kato, J; Kawagoe, Y; Kitamura, K; Kuwasako, K; Tokashiki, M | 1 |
| Charolidi, N; Cockerill, GW; Laing, K; Nohturfft, A; Pearce, S; Pirianov, G; Torsney, E | 1 |
| Johnson, AK; Thunhorst, RL; Xu, J | 1 |
| Cercek, B; Chyu, KY; Dimayuga, PC; Honjo, T; Lio, WM; Shah, PK; Trinidad, P; Yano, J; Zhao, X; Zhou, J | 1 |
| Chang, L; Guo, B; Jin, X; Li, Y; Liu, S; Miao, C; Wang, Y; Yan, J; Yang, R; Zhang, H | 1 |
| Antoniak, S; Bergmeier, W; Boulaftali, Y; Daugherty, A; Denny, JC; Edwards, TL; Geddings, JE; Jahangir, E; Mackman, N; Owens, AP; Sampson, UKA; Wei, WQ | 1 |
| Chen, CX; Gao, JP; Gu, WL; Huang, XY | 1 |
| Bernstein, KE; Giani, JF; Gonzalez-Villalobos, RA; Han, J; Janjulia, T; McDonough, AA; Rodriguez-Iturbe, B; Shen, XZ; Toblli, JE | 1 |
| Červenka, L; Červenková, L; El-Dahr, SS; Husková, Z; Jíchová, Š; Kopkan, L; Saifudeen, Z | 1 |
| Kami, A; Komano, H; Liu, J; Liu, S; Maeda, T; Matsumoto, Y; Michikawa, M; Murakami, S; Sugakawa, Y; Tanabe, C; Zou, K | 1 |
| Balakrishnan, A; Cassis, LA; Daugherty, A; Howatt, DA; Moorleghen, JJ; Poduri, A; Rateri, DL | 1 |
| Bamboye, MA; Brewer, AC; Ghigo, A; Gondim, ANS; Hirsch, E; Lederer, WJ; Martin, D; Perino, A; Prosser, BL; Santos, CX; Shah, AM; Ward, CW; Zhang, M | 1 |
| Abbate, A; Carbone, S; Gill, R; Marchetti, C; Mauro, AG; Mezzaroma, E; Regan, JA; Salloum, FN; Toldo, S; Valle Raleigh, J; Van Tassell, BW | 1 |
| Basile, DP; Collett, JA; Ivancic, CM; Mehrotra, P; Patel, JB | 1 |
| Nakagawasai, O; Nemoto, W; Ogata, Y; Tadano, T; Tan-No, K; Yaoita, F | 1 |
| Conte, D; Minas, JN; Nishiyama, A; Ortiz, RM; Thorwald, MA; Vázquez-Medina, JP | 1 |
| Chen, Y; Cui, JG; He, YM; Wang, PW; Wang, TZ; Wang, WJ; Yang, HJ; Yang, Q; Zhang, T | 1 |
| Atanasova, D; Ivanova, NM; Lazarov, N; Mitreva, R; Pechlivanova, DM; Stoynev, AG; Tchekalarova, JD | 1 |
| Cunningham, MW; Kem, DC; Li, H; Liles, C; Liles, JT; Murphy, TA; Veitla, V; Yu, X | 1 |
| Bihl, JC; Chen, S; Chen, Y; Ma, X; Xiao, X; Zhang, C; Zhao, B; Zhao, Y | 1 |
| Barreto-Chaves, ML; da Silva, IB; Lino, CA; Monteiro, Pde S; Shibata, CE | 1 |
| Beltz, TG; Clayton, SC; Hurley, SW; Johnson, AK; Thunhorst, RL; Xue, B; Zhang, Z | 1 |
| Bernstein, EA; Bernstein, KE; Giani, JF; Harrison, DG; Janjulia, T; Li, Y; Shah, KH; Shen, XZ; Shi, P; Zhao, T | 1 |
| Bagley, J; Baur, WE; Beasley, D; Galper, JB; Libby, P; Park, HJ; Qin, Z; Sukhova, G; Zhang, Y | 1 |
| Bragina, ME; Caffa, I; Costa-Fraga, FP; da Silva, RF; Fraga-Silva, RA; Mach, F; Montecucco, F; Nencioni, A; Raizada, MK; Santos, RAS; Stergiopulos, N | 1 |
| Fraga-Silva, RA; Piersigilli, A; Segers, P; Stergiopulos, N; Trachet, B | 1 |
| Potteaux, S; Tedgui, A | 1 |
| Daugherty, A; Liu, J; Lu, H | 1 |
| Dodos, M; Glass, MJ; Iadecola, C; Justice, NJ; Marques-Lopes, J; Milner, TA; Pickel, VM; Van Kempen, TA; Woods, C | 1 |
| Fraga-Silva, RA; Jacquet, PA; Segers, P; Stergiopulos, N; Trachet, B | 1 |
| Cai, Q; Chen, J; Huang, H; Liu, X; Liu, Y; Wang, J; Zhang, K | 1 |
| Davisson, RL; Young, CN | 1 |
| Chang, BI; Cheng, MH; Cheng, TL; Hsu, YY; Lai, CH; Li, YH; Luo, CY; Ma, CY; Shi, GY; Tsai, HW; Wang, KC; Wu, HL | 1 |
| Bobik, A; Chan, CT; Diep, H; Drummond, GR; Ferens, D; Guzik, TJ; Kett, MM; Kim, HA; Krishnan, SM; Kyaw, TS; Lewis, CV; Lieu, M; Peter, K; Salimova, E; Samuel, CS; Sobey, CG; Tipping, P; Toh, BH; Vinh, A | 1 |
| Goldschmidt, A; Maurer, M; Meyer, N; Schumacher, A; Woidacki, K; Zenclussen, AC | 1 |
| Karasawa, T; Kawashima, A; Kimura, H; Kobayashi, M; Komada, T; Ohkuchi, A; Shirasuna, K; Takahashi, M; Taniguchi, S; Usui, F | 1 |
| Baravian, C; Edagha, I; Gallego-Delgado, J; Rodriguez, A; Ruiz-Ortega, M; Ty, MC; Xu, W | 1 |
| Akiki, R; Bachschmid, M; Cohen, RA; Fry, JL; Gao, YZ; Morgan, KG; Seta, F; Shiraishi, Y; Turcotte, R; Yu, X; Zhang, Y | 1 |
| Issakainen, T; Korpela, R; Salmenkari, H; Vapaatalo, H | 1 |
| Chen, F; Chen, X; Deng, Y; Ding, D; Du, Y; Hu, X; Liao, Y; Qiu, Z; Wang, L; Wang, M; Wang, S; Wu, H; Yan, S; Yang, S; Yu, X; Zhang, H; Zhou, Y; Zhou, Z | 1 |
| Brdar, M; Dear, AE; Gaspari, T; Hu, Y; Lee, HW; Simpson, RW; Spizzo, I; Widdop, RE | 1 |
| Han, Y; Li, P; Sun, HJ; Zhang, F | 1 |
| Marston, S; Smoktunowicz, N; Song, W; Wilkinson, R | 1 |
| Devarajan, S; Habe, S; Miura, S; Nishiyama, A; Saku, K; Uehara, Y; Urata, H; Yahiro, E | 1 |
| Balakrishnan, A; Cassis, LA; Daugherty, A; Howatt, DA; Lu, H; Moorleghen, JJ; Rateri, DL | 1 |
| Bethmann, D; Gekle, M; Heise, C; Hünerberg, M; Mildenberger, S; Offermanns, S; Rabe, S; Schreier, B; Sibilia, M | 1 |
| Burke, SL; Head, GA; Lim, K; Moretti, JL | 2 |
| Brooks, HL; Konhilas, JP; Pollow, DP; Romero-Aleshire, MJ; Sanchez, JN | 1 |
| Capone, C; Claassen, JA; Heerschap, A; Kiliaan, AJ; Mellendijk, L; Wiesmann, M; Zerbi, V | 1 |
| Dong, X; Wang, X; Wei, L; Yin, Z; Zhang, L; Zhou, H | 1 |
| Li, F; Li, HH; Nie, H; Ren, H; Tian, C; Wang, L; Zheng, Y | 1 |
| Cheng, X; Daugherty, A; Fernandes, C; Huang, X; Johnsen, SP; Levy, BD; Liao, M; Libby, P; Lindholt, JS; Liu, CL; Ren, J; Shi, GP; Sukhova, GK; Wang, Y; Wemmelund, H; Zhang, JY; Zhou, Y | 1 |
| Guo, T; Hou, J; Huang, H; Long, H; Wang, J; Wang, T; Wu, Q; Xing, Y; Yan, P; Zheng, S; Zhong, T; Zhou, C | 1 |
| Gao, Y; Kong, W; Li, G; Wu, W; Yu, C; Zheng, J; Zhong, F | 1 |
| Li, C; Wang, G; Wu, J; Yuan, W; Zhang, Q | 2 |
| Beltz, TG; Felder, RB; Guo, F; Johnson, AK; Thunhorst, RL; Xue, B; Yu, Y | 1 |
| Chen, H; Littrup, PJ; Maliszewska-Scislo, M; Pajewski, R; Rossi, NF | 1 |
| Cai, Z; Chu, S; Cui, M; He, B; Hu, L; Shen, L; Sun, Z; Wang, X; Yi, J | 1 |
| Amstutz, C; Aubert, JF; Bouzourène, K; Mazzolai, L; Pellegrin, M | 1 |
| Jamba, A; Kagami, S; Kinoshita, Y; Kondo, S; Nagai, T; Urushihara, M | 1 |
| Ilatovskaya, DV; Levchenko, V; Lowing, A; Palygin, O; Shuyskiy, LS; Staruschenko, A | 1 |
| Glass, MJ; Iadecola, C; Marques-Lopes, J; Milner, TA; Narayan, A; Pickel, VM; Van Kempen, TA; Waters, EM | 1 |
| Chen, S; Levi, M; Li, C; Lin, Y; Luo, R; Wang, F; Wang, W; Yang, T; Zheng, P | 1 |
| Balakrishnan, A; Cassis, LA; Chen, X; Crooke, RM; Daugherty, A; Feldman, DL; Graham, MJ; Howatt, DA; Lu, H; Moorleghen, JJ; Mullick, AE; Vander Kooi, CW; Wu, C; Zhao, M | 1 |
| Dong, Z; Huang, Q; Hultström, M; Lai, EY; Li, H; Qi, Y; Wang, H; Wang, R; Wei, X; Wilcox, CS; Wu, H; Zhou, R; Zhou, X | 1 |
| Koltsova, EK; Peshkova, IO; Schaefer, G | 1 |
| Sheppard, D; Tsujino, K | 1 |
| Bang, JH; Han, JS; Jeon, WK; Kang, HW; Kim, MS; Lee, J | 1 |
| Cheng, CJ; Fang, YW; Hsu, HM; Lin, SH; Tseng, MH; Yang, SS | 1 |
| Fujigaki, Y; Ishigaki, S; Isobe, S; Kato, A; Miyajima, H; Nishiyama, A; Ohashi, N; Sakao, Y; Tsuji, T; Yasuda, H | 1 |
| Brandon-Warner, E; Bridges, CR; Fargnoli, AS; Hajjar, RJ; Katz, MG; Kendle, AP; Schrum, LW; Williams, RD | 1 |
| Bhimaraj, A; Celis, R; Cordero-Reyes, AM; Estep, JD; Flores-Arredondo, JH; Hamilton, DJ; Orrego, CM; Torre-Amione, G; Trevino, AR; Youker, KA | 1 |
| Granger, DN; Senchenkova, E; Yildirim, A | 1 |
| Bagi, Z; Cassis, LA; Chen, F; Fulton, DJ; Kitchens, J; Pati, P; Rudic, RD; Stepp, DW; Wang, Y | 1 |
| Cogle, CR; Harrison, JK; Kim, S; Luo, D; Raizada, MK; Scott, EW; Zingler, M | 1 |
| Gan, X; Lu, L; Miao, N; Shen, Y; Xu, D; Xu, J; Xue, H; Zhang, W; Zhou, L | 1 |
| Egashira, K; Katsuki, S; Koga, J; Matoba, T; Nakano, K; Nakashiro, S; Sunagawa, K; Tokutome, M; Umezu, R | 1 |
| Chen, J; He, P; Jiang, L; Liu, Y; Tan, N; Wei, X | 1 |
| Baumbach, GL; Chan, SL; Houwen, FK; Umesalma, S | 1 |
| Cai, X; Fu, Y; Gao, X; Guan, Y; Li, Y; Su, G; Wang, L; Wang, S | 1 |
| Albertini, R; Avanzini, MA; Bedino, G; Corradetti, V; Dal Canton, A; Esposito, P; Gregorini, M; Ingo, D; Libetta, C; Mantelli, M; Milanesi, S; Pattonieri, EF; Peressini, S; Rampino, T; Rocca, C; Serpieri, N; Valsania, T | 1 |
| Budish, RA; Chappell, MC; Hutson, DD; Kashyap, S; Lindsey, SH; Liu, L; Miller, KS; Murphy, B; Trask, AJ; Trimmer, EH; Zimmerman, MA | 1 |
| Bloch, DB; Bloch, KD; Buys, ES; Cheng, J; Ernande, L; Kolodziej, SA; Leyton, PA; Mayeur, C; Rhee, DK; Scherrer-Crosbie, M; Shahid, M; Spagnolli, E; Tainsh, RE; Thoonen, R; Wu, MX; Zapol, WM | 1 |
| Chen, H; Han, LM; He, JL; Li, BY; Liang, XB; Liu, Y; Lu, XL; Qiao, GF; Shou, W; Wang, LQ; Wu, D; Zhou, JY; Zhou, YH | 1 |
| Cheng, QJ; Li, XX; Liu, CL; Wang, JH; Wang, YH; Yuan, CT | 1 |
| Aslanidou, L; Astolfo, A; Fraga-Silva, RA; Piersigilli, A; Segers, P; Sordet-Dessimoz, J; Stampanoni, MF; Stergiopulos, N; Trachet, B | 1 |
| Bai, J; Ding, L; Gu, R; Li, Q; Li, R; Wang, B; Wang, L; Xie, J; Xu, B | 1 |
| Aoki, T; Ikeda, S; Kadomatsu, K; Kikuchi, N; Kurosawa, R; Miyata, S; Mukherjee, R; Nogi, M; Numano, K; Omura, J; Otsuki, T; Satoh, K; Satoh, T; Shimokawa, H; Spinale, FG; Sugimura, K; Sunamura, S; Suzuki, K; Tatebe, S | 1 |
| Antunes, TT; Callera, GE; He, Y; Ryazanov, AG; Ryazanova, LV; Shrier, A; Stewart, DJ; Touyz, RM; Yogi, A; Zhai, A | 1 |
| Brand, DD; Gonzalez, FJ; Kara, M; Katsurada, A; Majid, DS; Malik, KU; Navar, LG; Pingili, AK; Thirunavukkarasu, S | 1 |
| Chang, YK; Choi, DE; Chung, S; Jeong, JY; Lee, KW; Lim, BJ; Na, KR | 1 |
| Cortopassi, G; David, S; McMackin, MZ; Raetz, A; Shan, Y; Shen, Y | 1 |
| Chen, HS; Jiang, FY; Li, RS; Li, WJ; Tu, Q; Wang, Y; Yin, RX | 1 |
| Biros, E; Dougan, T; Gera, L; Golledge, J; Jose, RJ; Moran, CS; Norman, PE; Rush, CM | 1 |
| Balakrishnan, A; Baud, L; Chishti, AH; Howatt, DA; Moorleghen, JJ; Muniappan, L; Rateri, DL; Saido, TC; Subramanian, V; Takano, J; Uchida, HA | 1 |
| Bakker, EN; Palao, T; Rippe, C; Swärd, K; van Veen, H; VanBavel, E | 1 |
| Atkins, GB; Dong, N; Gerson, SL; Golledge, J; Hiraoka, S; Kuivaniemi, H; Lin, Z; Moxon, JV; Norman, P; Perbal, B; Prosdocimo, DA; Qing, Y; Rittié, L; Shi, GP; Shi, H; Takemoto, M; van der Voort, D; Yokote, K; Zhang, C; Zhang, R | 1 |
| Ahmad, S; Alencar, A; da Silva, J; Ferrario, CM; Groban, L; Lin, MR; Sun, X; Wang, H; Zapata-Sudo, G | 1 |
| Chen, Y; Chen, YE; Fan, J; Kang, D; Li, S; Liu, E; Niimi, M; Ning, B; Shiomi, M; Wang, YN; Wang, Z; Waqar, AB; Yu, Q; Zhang, J | 1 |
| Aguiló, S; Camacho, M; Dilmé, J; Galán, M; Martínez-González, J; Orriols, M; Rodriguez, C; Rodríguez, JA; Varona, S | 1 |
| Alvarez-Prats, A; Baranova, IN; Bocharov, AV; Eggerman, TL; Hu, X; Huang, YG; Mullick, AE; Patterson, AP; Remaley, AT; Souza, AC; Star, RA; Street, JM; Vishnyakova, TG; Wilkins, KJ; Yuen, PS | 1 |
| Asada, Y; Chosa, E; Funamoto, T; Hao, Y; Hatakeyama, K; Kato, J; Kitamura, K; Kurogi, S; Nakamura, M; Sakamoto, S; Sekimoto, T; Sekita-Hatakeyama, Y; Tsuruda, T; Udagawa, N | 1 |
| Bellini, C; Bersi, MR; Harrison, DG; Humphrey, JD; Montaniel, KRC; Wu, J | 1 |
| Fang, J; Gong, J; Guo, JH; Ji, YX; Li, H; Liu, HY; Wei, X; Zhao, GN; Zhu, X | 1 |
| Beltz, TG; Felder, RB; Guo, F; Johnson, AK; Thunhorst, RL; Xue, B; Yu, Y; Zhang, Z | 1 |
| He, X; Li, Z; Liu, W; Liu, X; Liu, Y; Wang, B; Wang, T; Zeng, H | 1 |
| Crespo-Garcia, S; Dechend, R; Dillinger, A; Fuchshofer, R; Haase, N; Herrspiegel, C; Joussen, AM; Kociok, N; Luft, FC; Müller, DN; Poglitsch, M; Reichhart, N; Skosyrski, S; Strauß, O | 1 |
| Böhm, M; Dhein, S; Hohl, M; Kabiri, M; Linz, D; Reil, JC; Ruf, S; Sadowski, T; Schotten, U; Verheule, S; Wohlfart, P | 1 |
| Ding, F; Ding, J; Li, B; Li, X; Zhang, X | 1 |
| Chang, AY; Chen, JY; Jiang, MJ; Lai, CH; Li, YH; Lin, SC; Maeda, N; Tai, HC; Teng, SH; Tsai, PJ; Tsai, YS; Wang, KC; Wu, HL | 1 |
| Czesla, D; Ehmke, H; Köhl, J; Kurts, C; Meyer-Schwesinger, C; Rosendahl, A; Stahl, RA; Weiss, S; Wenzel, UO; Zipfel, PF | 1 |
| Bikineyeva, AT; Dikalov, SI; Dikalova, AE; Harrison, DG; Itani, HA; McMaster, WG; Nazarewicz, RR | 1 |
| Glass, MJ; Iadecola, C; Israilov, S; Marques-Lopes, J; Milner, TA; Pickel, VM; Tesfaye, E; Van Kempen, TA; Wang, G; Waters, EM | 1 |
| Camacho, M; Escudero, JR; Galán, M; Guadall, A; Martí-Pàmies, I; Martín-Ventura, JL; Martínez-González, J; Orriols, M; Rodríguez, C; Varona, S; Vila, L | 1 |
| Faraci, FM; Kinzenbaw, DA; Li, Y; Modrick, ML; Pewe, LL | 1 |
| Chu, ML; Dong, H; Joyce, J; Khan, SA; Sasaki, T; Tsuda, T | 1 |
| Bai, R; Bian, Y; Liang, B; Liu, G; Lu, Y; Qin, W; Song, X; Sun, X; Xiao, C | 1 |
| Burgess, DJ; Cuffe, JS; Moritz, KM; O'Sullivan, L; Singh, RR | 1 |
| Chen, D; Coffman, TM; Griffiths, R; Gurley, SB; Herrera, M; Kohan, D; Sparks, MA; Stegbauer, J | 1 |
| Dale, BL; Gnecco, J; Hoover, RS; Iwakura, Y; Kamat, NV; Ko, B; Madhur, MS; McDonough, AA; Norlander, AE; Saleh, MA; Zhu, L | 1 |
| Acs, N; Arbib, N; Hetthéssy, JR; Matrai, M; Mericli, M; Monos, E; Nadasy, GL; Szekacs, B; Varbiro, S | 1 |
| Lionetti, V | 1 |
| Ding, Z; Ge, J; Gong, H; Jiang, Q; Kang, L; Li, Y; Wang, S; Wang, X; Wu, J; Ye, Y; Yin, P; Yuan, J; Zhang, W; Zou, Y | 1 |
| Bonami, RH; Chen, W; Guzik, TJ; Harrison, DG; Itani, HA; Januszewicz, A; Kaszuba, AM; Konior, A; Madhur, MS; Marshall, AF; McMaster, WG; Mikolajczyk, TP; Moore, DJ; Nazarewicz, RR; Norlander, AE; Poffenberger, G; Prejbisz, A; Saleh, MA; Weyand, CM | 1 |
| Al-Salami, H; Elahy, M; Lam, V; Mamo, JC; Mooranian, A; Negrulj, R; Takechi, R | 1 |
| Chen, L; Chen, QH; Kang, LN; Li, GN; Li, R; Wu, H; Xie, J; Xu, B; Zhang, XL | 1 |
| Ji, ZZ; Xu, YC | 1 |
| Bai, YQ; Liu, YF; Qi, M | 1 |
| Asirvatham-Jeyaraj, N; Fink, GD | 1 |
| Deussen, A; Kopaliani, I; Martin, M; Müller, B; Zatschler, B | 1 |
| Abd-Elrahman, KS; Boisvert, NC; Carter, A; Cron, GO; Ferguson, SS; He, Y; Holterman, CE; Hsu, KJ; Kennedy, CR; Thibodeau, JF | 1 |
| Burke, SD; Clark, CD; DuPont, JJ; Jaffe, IZ; Kang, PM; Karumanchi, SA; Khankin, EV; Lo, AS; McCurley, A; Moss, ME; Rajakumar, A; Seely, EW; Stillman, IE; Wang, A; Zhang, D; Zsengellér, ZK | 1 |
| Dai, HL; Gaung, XF; Hu, WY; Jiang, LH; Li, L; Xiao, ZC | 1 |
| Collado, A; Gonzalez-Navarro, H; Hueso, L; Martorell, S; Piqueras, L; Sanz, MJ | 1 |
| Fang, P; Geng, J; Li, Z; Liu, Q; Lu, D; Shan, Q; Wang, K; Wang, S; Wang, Y; Zhang, Q | 1 |
| Brand, DD; Ghafoor, HU; Gonzalez, FJ; Khan, NS; Malik, KU; Song, CY; Thirunavukkarasu, S | 1 |
| Levin, ER; Narayanan, R; Pedram, A; Razandi, M | 1 |
| Dorri Mashhadi, F; Hafizi, Z; Jamhiri, M; Safari, F; Zare Mehrjardi, F; Zavvar Reza, J | 1 |
| Du, J; Jia, L; Lan, F; Liu, Y; Piao, C; Ren, W; Wang, X | 1 |
| Fu, H; Huang, F; Li, DJ; Ni, M; Shen, FM; Zhang, LS | 1 |
| Dimberg, J; Folkesson, M; Gabrielson, M; Länne, T; Matussek, A; Skogberg, J; Vorkapic, E; Wågsäter, D; Welander, M | 1 |
| Chen, J; Diao, X; Duan, W; Pan, Z; Ren, X; Shen, Q; Wang, C | 1 |
| Chen, W; Dong, H; Dong, S; Gao, X; Lv, G; Shao, S; Zhang, L | 1 |
| Aoyama, M; Bando, YK; Kawase, H; Monji, A; Murohara, T; Nishimura, K | 1 |
| Chen, YH; Hou, JW; Li, CY; Li, YG; Wang, H; Wang, Q; Wang, YP | 1 |
| Kent, KC; Takei, Y; Tanaka, T; Yamanouchi, D | 1 |
| De Silva, TM; Faraci, FM; Kinzenbaw, DA; Modrick, ML; Reinhardt, LD | 1 |
| Long, HB; Luo, KQ; Xu, BC | 1 |
| Cos, P; De Meester, I; Domen, A; Driessens, E; Gielis, JF; Kehoe, K; Lambeir, AM; Maes, L; Van Elzen, R; Van Schil, PE; Verkerk, R; Vliegen, G | 1 |
| Chen, H; Chen, Y; Chu, J; He, F; Lin, S; Peng, J; Shen, A; Xiao, F | 1 |
| Ishida, T; Kume, S; Kurita, S; Ogita, H; Pang, X; Shimizu, A; Takeuchi, K; Yasuda-Yamahara, M; Zankov, DP | 1 |
| Balakrishnan, A; Daugherty, A; Graham, MJ; Howatt, DA; Lu, H; Mullick, AE | 1 |
| Ait-Aissa, K; Belmadani, S; Gabani, M; Haddox, S; Irani, K; Kassan, M; Mali, V; Matrougui, K; Radwan, E; Trebak, M; Zhang, W | 1 |
| Eguchi, S; Elliott, KJ; Forrester, SJ; Kawai, T; Kwok, HF; Nuti, E; Obama, T; Rizzo, V; Rossello, A; Scalia, R; Takayanagi, T; Tsuji, T | 1 |
| Jin, X; Li, G; Shen, L; Wu, X; Yang, L; Yuan, H | 1 |
| Huang, S; Jin, SY; Li, X; Li, Y; Ling, XG; Luo, XY; Ma, XX; Ning, ZW; Pan, MX; Wang, D; Wang, GZ; Yang, RQ | 1 |
| Bao, M; Cao, Q; Dai, M; Hu, D; Huang, C; Huang, H; Tang, Y; Wang, X; Yu, L; Zhang, Y | 1 |
| Deng, X; Duan, Q; Hu, Q; Huang, H; Liao, C; Mao, X; Plutzky, J; Qi, J; Sun, Z; Yang, T; Zhang, G; Zhou, H | 1 |
| De Mello, W | 1 |
| Basu, R; Fan, D; Fernandez-Patron, C; Kassiri, Z; Oudit, GY; Patel, V; Samokhvalov, V; Seubert, JM; Shen, M; Takawale, A; Wang, X | 1 |
| Chiba, Y; Imanishi, M; Matsunaga, S; Nakagawa, T; Tamaki, T; Tomita, N; Tomita, S; Ueno, M; Yamamoto, K | 1 |
| Ding, H; Ding, S; Gao, L; He, B; Pu, J; Xu, L; Yao, T; Ying, X; Yuan, A; Zhao, Y | 1 |
| De Meyer, GR; Martinet, W; Roth, L; Schrijvers, DM | 1 |
| Claassen, JA; Heerschap, A; Kiliaan, AJ; Roelofs, M; van der Lugt, R; Wiesmann, M | 1 |
| Han, J; McDonough, AA; Ralph, DL; Veiras, LC | 1 |
| Chang, CP; Chen, HS; Cheng, W; Feng, X; Han, P; Lin, CH; Quertermous, T; Shang, C; Yang, J; Zhou, Q | 1 |
| Cheng, YJ; Gao, XR; Liu, LJ; Lu, GH; Tang, K; Wu, SH; Xu, CG; Xu, Z; Yao, FJ | 1 |
| Ailawadi, G; Almenara, CC; Butts, C; Downs, EA; Leitinger, N; McNamara, CA; Meher, AK; Schaheen, B; Serbulea, V; Spinosa, M; Srikakulapu, P; Su, G; Upchurch, GR; Zhao, Y | 1 |
| Khanmoradi, M; Nasimi, A | 1 |
| Chen, HZ; Fu, WY; Gao, P; Han, L; Liu, DP; Liu, Y; Lu, J; Pei, JF; Tang, X; Wang, F; Wang, XM; Xu, TT; Yan, YF; Zhang, R; Zhang, ZQ; Zou, MH | 1 |
| Chen, L; Cheng, G; Huang, X; Liu, Z; Peng, H; Shi, R; Xu, Q; Yang, T; Yang, W; Yu, Z; Zhang, G | 1 |
| Carrón, R; Gómez-Roso, M; Montero, MJ; Sevilla, MA | 1 |
| Haack, KK; Pellegrino, PR; Schiller, AM; Zucker, IH | 1 |
| Chen, Y; Cui, W; Du, J; Fassett, J; Li, HH; Ma, YQ; Ren, HL; Wang, L; Xia, YL; Yang, YZ; Zhao, XC; Zhou, X | 1 |
| Choi, YS; de Mattos, AB; Kim, M; Kolwicz, SC; Li, T; Nabben, M; Shao, D; Tian, R; Wang, W | 1 |
| Bian, ZY; Deng, W; Jin, YG; Li, H; Shen, DF; Tang, QZ; Wang, SS; Wu, QQ; Yan, L; Yang, Z; Yuan, Y; Zeng, XF; Zhou, H | 1 |
| Chen, J; Lin, SY; Long, Q; Ni, L; Yin, Y; You, L; Zhang, JY; Zhang, Q | 1 |
| Li, Y; Sun, L; Wang, Y; Yan, S; Yang, G; Yang, X; Yu, C | 1 |
| Cheng, JD; Deng, CY; Fu, YH; Hu, ZQ; Lin, QX; Liu, FZ; Shan, ZX; Tang, CM; Wu, SL; Yang, H; Zheng, XL; Zhu, JN | 1 |
| Barrett, E; Best, AK; Broseghini-Filho, GB; Butcher, JT; Cabot, M; Chechova, S; Columbus, L; DeLalio, LJ; Doctor, A; Good, ME; Hu, S; Isakson, BE; Keller, TC; Le, TH; Martin, JN; Marziano, C; Ning, B; Peirce, SM; Purdy, M; Rogers, S; Shu, X; Simão Padilha, A; Yeager, M | 1 |
| Fu, YH; Hu, ZQ; Lin, QX; Shan, ZX; Tang, CM; Wu, SL; Xiao, Z; Yang, M; Zhang, Z; Zheng, XL; Zhu, JN; Zhu, WS | 1 |
| Anrather, J; Chang, H; Faraco, G; Garcia-Bonilla, L; Iadecola, C; Lane, D; Murphy, M; Racchumi, G; Santisteban, MM; Sugiyama, Y; Van Rooijen, N | 1 |
| Chen, J; Chen, M; Gu, J; He, L; Hu, H; Jing, Y; Li, L; Mei, C; Mei, S; Qi, N; Song, S; Sun, L; Wu, M; Wüthrich, RP; Yang, M | 1 |
| Meissner, A; Minnerup, J; Planas, AM; Soria, G | 1 |
| Chege Gitau, S; E, X; Guo, Z; Huangfu, L; Li, T; Li, X; Liang, H; Qian, M; Qili, M; Shan, H; Wang, L; Wu, Q; Xu, B; Xu, C; Zhao, D | 1 |
| Chen, XQ; Duan, SZ; Li, C; Liu, X; Shen, ZX; Shi, HJ; Sun, JY; Sun, XN; Wang, J; Zhang, JW; Zhang, WC; Zhang, YY; Zheng, XJ | 1 |
| Boyer, MJ; Eguchi, S; Elliott, KJ; Forrester, SJ; Kawai, T; Obama, T; Preston, KJ; Rizzo, V; Yan, Z | 1 |
| Chen, HZ; Gao, P; Liu, DP; Pei, JF; She, ZG; Wang, F; Wang, TT; Yan, YF; Zhang, R; Zhang, Y; Zhang, ZQ | 1 |
| Li, X; Liu, X; Tian, Y; Wang, J; Wu, J; Yu, X | 1 |
| Bernstein, EA; Bernstein, KE; Eriguchi, M; Fuchs, S; Giani, JF; Gonzalez-Villalobos, RA; Katsumata, M; Li, L; McDonough, AA; Shen, XZ | 1 |
| Akerman, AW; Ikonomidis, JS; Jones, JA; Kimbrough, D; Mukherjee, R; Nadeau, EK; Ruddy, JM; Stroud, RE | 1 |
| Carreón-Torres, E; Del Valle-Mondragón, L; Díaz-Díaz, E; Guarner-Lans, V; Ibarra-Lara, L; Rubio-Ruiz, ME; Sánchez-Aguilar, M; Sánchez-Mendoza, A; Soria-Castro, E; Vázquez-Meza, H | 1 |
| Chen, X; Gao, X; Lu, G; Luo, C; Luo, J; Peng, L; Zuo, Z | 1 |
| Grave, K; Hering, L; Hoch, H; Mergia, E; Potthoff, SA; Rump, LC; Sivritas, SH; Stegbauer, J; Thieme, M; Yang, G | 1 |
| Han, Y; Li, Y; Liu, D; Liu, H; Liu, M; Liu, Y; Peng, C; Song, H; Tian, X; Yan, C; Zhang, J; Zhang, Q; Zhang, X; Zhang, Y | 1 |
| Jiménez-Altayó, F; Jurado, A; Meissner, A; Miro, F; Planas, AM; Vila, E | 1 |
| Granger, DN; Kevil, CG; Krzywanski, DM; Leskov, I; Neville, A; Pardue, S; Shen, X | 1 |
| Milewicz, DM; Prakash, SK; Ramirez, F | 1 |
| Jackson, EK; Zhu, X | 1 |
| Ji, Y; Jing, H; Wang, D; Zhai, G | 1 |
| Chen, X; Dong, B; Dong, X; Hao, Q; Shi, H; Wang, X; Yan, F | 1 |
| Baek, CH; Chang, JW; Kim, H; Lee, RB; Lee, SK; Yang, WS | 1 |
| Ask, K; Carlisle, RE; Dickhout, JG; Krepinsky, JC; Lu, C; Lukic, D; Marway, MK; Mohammed-Ali, Z | 1 |
| Coselli, JS; Curci, JA; LeMaire, SA; Lloyd, EE; Milewicz, DM; Ren, P; Shen, YH; Wu, D; Xie, W; Xu, G; Zhang, L; Zhang, Q; Zhang, S; Zheng, Y | 1 |
| He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM | 1 |
| Bartosiewicz, J; Kaminski, T; Karbowska, M; Pawlak, D; Pawlak, K; Tankiewicz-Kwedlo, A | 1 |
| Jiang, X; Kong, J; Li, H; Liu, S; Qin, X; Wang, J; Yang, J; Zhang, C; Zhang, W; Zhang, Y | 1 |
| Chen, Y; Dong, B; Guo, T; Li, P; Liang, WJ; Liu, C; Ma, H; Pang, XY; Shan, MR; Wang, SX; Wang, XQ; Wang, YL; Yin, YL; Yu, HY; Zhou, SN | 1 |
| Dale, BL; Laroumanie, F; Madhur, MS; Saleh, MA | 1 |
| Bai, Y; Cai, L; Kong, L; Liu, F; Tan, Y; Wang, Y; Wu, H; Xin, Y | 1 |
| Lopez Gelston, CA; Mitchell, BM | 1 |
| Han, F; Li, J; Liu, M; Mao, C; Yang, P | 1 |
| Beltz, TG; Guo, F; Johnson, AK; Thunhorst, RL; Xue, B; Yin, H | 1 |
| Balachandran, K; Diaz, N; Martindale, C; Perez, J; Plate, R; Tandon, I | 1 |
| Bond Lau, W; Du, J; Li, P; Li, Y; Li, Z; Ma, XL; Wang, C; Wu, Y; Zhang, C | 1 |
| Akazawa, H; Ikeda, Y; Isobe, M; Komuro, I; Koriyama, H; Kumagai, H; Maejima, Y; Morishita, R; Nakagami, H; Shimamura, M; Suzuki, JI; Wakayama, K; Watanabe, R | 1 |
| Huang, J; Liu, X; Lu, L; Niu, Y; Wang, Y; Yu, C; Yu, Y; Zhao, L; Zhou, L | 1 |
| Chen, H; Cui, Y; Li, S; Liu, J; Song, J; Zhang, F | 1 |
| Egashira, T; Fukuda, K; Hashimoto, H; Hayashi, K; Hayashiji, N; Ito, S; Kashimura, S; Kodaira, M; Kunitomi, A; Kusumoto, D; Lachmann, M; Motoda, C; Nagai, T; Nakanishi, C; Sakata, K; Seki, T; Shimojima, M; Takei, M; Tohyama, S; Yamagishi, M; Yozu, G; Yuasa, S | 1 |
| Ashpole, N; Csiszar, A; Fulop, GA; Gautam, T; Giles, CB; Sonntag, WE; Springo, Z; Tarantini, S; Ungvari, Z; Valcarcel-Ares, NM; Wren, JD; Yabluchanskiy, A | 1 |
| Drake, CT; Frys, K; Graustein, B; Iadecola, C; Lessard, A; Milner, TA; Mitterling, K; Torres-Reveron, A; Waters, EM | 1 |
| Schiffrin, EL | 3 |
| Carretero, OA; Cavasin, MA; Kuziel, WA; Liao, TD; Liu, YH; Pagano, PJ; Shesely, EG; Yang, XP | 1 |
| Fujita, T; Kaneko, T; Matsui, H; Ogura, S; Shimosawa, T; Takenaka, K; Uetake, Y; Wang, H; Yatomi, Y | 1 |
| Cornish, KG; Gao, L; Liu, D; Roy, SK; Zucker, IH | 1 |
| Guo, J; Hu, Z; Wang, Q; Wu, J; Wu, X; Xu, J; Yin, Z | 1 |
| Felder, RB; Wei, SG; Weiss, RM; Yu, Y; Zhang, ZH | 1 |
| Agnew, C; Ding, Y; Li, YL; Schultz, HD | 1 |
| Coker, SJ; Dempster, J; Farkas, A | 1 |
| Bousquet, P; de Champlain, J; Jaffré, F; Laplante, MA; Maroteaux, L; Monassier, L | 1 |
| Brook, RD; Cardounel, AJ; Chen, LC; Devlin, R; Hwang, JS; Rajagopalan, S; Sun, Q; Ying, Z; Yue, P; Zweier, JL | 1 |
| Kasparov, S; Paton, JF; Raizada, MK; Teschemacher, AG; Wang, S | 1 |
| Cao, G; Della Penna, S; Fernández, BE; Gorzalczany, S; Pandolfo, M; Rosón, MI; Toblli, JE | 1 |
| Al-Omran, M; Backx, PH; Levitt, KS; Lovren, F; Oudit, GY; Pan, Y; Penninger, JM; Peterson, MD; Quan, A; Shukla, PC; Slutsky, AS; Stewart, DJ; Teoh, H; Verma, S; Wang, G | 1 |
| Aragon, AC; Carbett, E; Goens, MB; Walker, MK | 1 |
| Ebrahimian, T; Sairam, MR; Schiffrin, EL; Touyz, RM | 1 |
| Irani, RA; Xia, Y | 1 |
| Abraham, NG | 1 |
| Kelsen, S; Stec, DE; Vera, T | 1 |
| Avila-Casado, C; Franco, M; Johnson, RJ; Nakagawa, T; Rodríguez-Iturbe, B; Sánchez-Lozada, LG; Sautin, YY; Soto, V; Tapia, E | 1 |
| Denton, KM; Flower, RL; Jones, ES; Moritz, KM; Sampson, AK; Widdop, RE | 1 |
| Chae, JK; Gul, R; Jang, KY; Kim, SY; Kim, UH; Ko, JK; Park, JH | 1 |
| Cohn, HI; Dorn, GW; Eckhart, AD; Harris, DM; Koch, WJ; Pesant, S; Pfeiffer, M; Zhou, RH | 1 |
| Bivona, BJ; Feng, Y; Harrison-Bernard, LM; Lazartigues, E; Park, S | 1 |
| Alitalo, K; Andersson, LC; Bry, M; Hassinen, IE; Helkamaa, T; Jeltsch, M; Karpanen, T; Kivelä, R; Leskinen, H; Liimatta, E; Merentie, M; Mervaala, E; Ollila, HM; Oresic, M; Paavonen, K; Seppänen-Laakso, T; Ylä-Herttuala, S | 1 |
| Akram, K; Fukai, T; Gongora, MC; Harrison, DG; Itoh, S; Ozumi, K; Qin, Z; Ushio-Fukai, M | 1 |
| Chang, MS; Wei, CC | 1 |
| Agrawal, R; Ali, ZA; Anderson, JP; Ashley, EA; Chun, HJ; Kojima, Y; Kundu, RK; Leeper, NJ; Lenardo, MJ; Patterson, AJ; Pearl, NE; Quertermous, T; Sheikh, AY; Tsao, PS; Zheng, L | 1 |
| Augustyniak, RA; Chen, H; Maliszewska-Scislo, M; Rossi, NF; Seth, D | 1 |
| Jing, L; Kou, JJ; Li, S; Li, WM; Song, J; Zhou, LJ | 1 |
| Dai, Q; Dong, P; Huang, Q; Jia, N; Jin, W; Liu, S; Zhang, J | 1 |
| Davis, BB; Fiehn, O; Hammock, BD; Inceoglu, B; Kim, IH; Morisseau, C; Tsai, HJ; Ulu, A; Weiss, RH | 1 |
| Chiu, AT; Smith, RD; Timmermans, PB; Wong, PC | 1 |
| Fleck, E; Holzmeister, J; Neuss, M; Regitz-Zagrosek, V | 1 |
| Belloni, AS; Guidolin, D; Maniero, C; Pessina, AC; Pothen, P; Rossi, GP; Seccia, TM | 1 |
| Bader, M; Baltatu, OC; Campos, LA; Iliescu, R; Oliveira, ML; Popova, E; Rentzsch, B; Santos, RA; Todiras, M | 1 |
| Blantz, RC; Deng, A; Satriano, J; Singh, P; Tang, T; Thomson, SC; Wang, C | 1 |
| Borges, GR; Fazan, R; Prado, CM; Rossi, MA; Salgado, HC; Silva, CA | 1 |
| Byku, M; Macarthur, H; Westfall, TC | 1 |
| Johnson, RJ; Rodriguez-Iturbe, B; Vaziri, ND | 1 |
| Chen, W; Khalil, RA | 1 |
| Berge, RK; Bivol, LM; Gudbrandsen, OA; Hultström, M; Iversen, BM | 1 |
| Accardi, JR; Miller, SA; St Onge, EL | 1 |
| Fukumoto, M; Ikeda, T; Ishizaki, E; Jin, D; Miyazaki, M; Oku, H; Sakaguchi, M; Sakonjo, H; Sugiyama, T; Takai, S | 1 |
| Barreto, NE; Bilusić, M; Boerwinkle, E; Curb, JD; Grigor, MR; Harris, EL; Hunt, SC; Jacob, HJ; Kwitek, AE; Moreno, C; Porteous, WK; Thompson, CM; Tschannen, MR; Weder, A | 1 |
| Cuzić, S; Knotek, M; Radović, N | 1 |
| Chen, QH; Guo, T; Liu, L; Qiu, HB; Yang, Y; Zhao, MM; Zhu, Y | 1 |
| Helle, F; Hultström, M; Iversen, BM; Palm, F; Skogstrand, T | 1 |
| Calvo, JJ; García, M; Hernández Lorenzo, MP; Hernández-Barbáchano, E; López Novoa, JM; San Román, JI | 1 |
| Bae, EH; Fenton, RA; Frøkiaer, J; Jensen, AM; Kim, SW; Nielsen, S; Nørregaard, R | 1 |
| Brown, RD; Carlström, M; Lai, EY; Ma, Z; Patzak, A; Persson, AE | 1 |
| Hayashi, T; Inoue, N; Jin, D; Katayama, H; Kitaura, Y; Miyazaki, M; Muramatsu, M; Takai, S; Tamai, H | 1 |
| Chen, K; Cui, WY; Liu, GS; Long, CL; Pan, ZY; Qin, XC; Wang, H; Zhang, YF | 1 |
| Higashikuni, Y; Hirata, Y; Koibuchi, N; Kugiyama, K; Nagai, R; Nakamura, K; Nishimatsu, H; Sata, M | 1 |
| Liu, XP; Pang, YJ; Sun, SJ; Sun, ZJ; Wang, YB; Zhao, TT; Zheng, M; Zhu, WW | 1 |
| Chen, SY; Deng, SX; Li, D; Li, YJ; Liao, DF; Qin, XP; Ren, JF; Tian, HH; Zeng, SY; Zheng, YB | 1 |
| Aoki, M; Fujiwara, Y; Makino, H; Miyake, T; Morishita, R; Nishimura, M; Shiraya, S; Yamakawa, S | 1 |
| Andersson, A; Fenhammar, J; Forestier, J; Frithiof, R; Hjelmqvist, H; Sollevi, A; Weitzberg, E | 1 |
| Hosoya, M; Morikawa, K; Murayama, Y; Ohashi, J; Shimokawa, H; Takaki, A; Yamagishi, H | 1 |
| Bravo, Y; Chavez, M; Johnson, RJ; Parra, G; Pons, H; Quiroz, Y; Rodriguez-Iturbe, B; Salazar, J | 1 |
| Chappell, MC; Diz, DI; Figueroa, JP; Rose, JC; Shaltout, HA | 1 |
| Aizawa, Y; Azuma, J; Dosaka, N; Iekushi, K; Koibuchi, N; Kusunoki, H; Morishita, R; Sanada, F; Taniyama, Y; Yokoi, T | 1 |
| Lee, JH; Palaia, T; Ragolia, L | 1 |
| Abraldes, JG; Arroyo, V; Bataller, R; Colmenero, J; Dominguez, M; Egido, J; Ginès, P; Moreno, M; Ramalho, F; Ramalho, LN; Ruiz-Ortega, M; Sancho-Bru, P | 1 |
| Hume, GE; Radford-Smith, GL | 1 |
| Gonzalez-Villalobos, RA; Katsurada, A; Kobori, H; Navar, LG; Satou, R; Semprun-Prieto, LC; Seth, DM | 1 |
| Amann, K; Buness, A; Lutz, D; Maercker, C; Petersen, I; Ridinger, H; Rutenberg, C | 1 |
| Gu, ZL; Guo, CY; Sheng, R; Xie, ML; Zhou, WX | 1 |
| Ashitate, T; Echizen, T; Katoh, C; Kushibiki, M; Magota, K; Okumura, K; Osanai, T; Tanaka, M; Tomita, H; Yamada, M | 1 |
| Campbell, KP; Chang, D; Chang, YT; Chen, CC; Chen, JJ; Chen, YC; Chen, YH; Chiang, CS; Chieng, H; Huang, CH; Shin, HS | 1 |
| Liu, JG; Xu, FQ; Xu, H | 1 |
| Bursell, SE; Chilcote, TJ; Clermont, AC; Feener, EP; Phipps, JA; Sinha, S | 1 |
| Brum, PC; Bueno, CR; Ferreira, JC; Irigoyen, MC; Krieger, JE; Mattos, KC; Oliveira, EM; Pereira, MG; Rosa, KT | 1 |
| Bek, MJ; Brand-Herrmann, SM; Duning, K; Gerard, C; Hsu, HH; Kreusser, S; Meyer, HH; Pavenstädt, H; Stölting, M; Telgmann, R; van Le, T; Weide, T | 1 |
| Evans, JF; Lee, JH; Ragolia, L | 1 |
| Fukuda, Y; Iino, Y; Ishizaki, M; Katayama, Y; Kawachi, H; Masuda, Y; Mii, A; Shimizu, A | 1 |
| Campos, AH; Maciel, TT; Melo, RS | 1 |
| Lee, DH; Leong, PK; Maunsbach, AB; McDonough, AA; Riquier, AD; Yang, LE | 1 |
| Raij, L; Schulman, IH; Zhou, MS | 2 |
| Boschmann, M; Contrepas, A; Dechend, R; Engeli, S; Graeske, S; Gratze, P; Janke, J; Klaus, S; Luft, FC; Malchow, J; Muller, DN; Nguyen, G; Plehm, R; Qadri, F; Springer, J | 1 |
| Curl, CL; Delbridge, LM; Huggins, CE; McLennan, PL; Patel, R; Pedrazzini, T; Pepe, S; Theiss, ML | 1 |
| Ramos, KS; Zhang, Y | 1 |
| Hiramatsu, N; Hiromura, K; Ikeuchi, H; Kaneko, Y; Kopp, JB; Kuroiwa, T; Maeshima, A; Nojima, Y; Sakurai, N; Shigehara, T; Takeuchi, S; Tomioka, M | 1 |
| Bekaert, V; Beretz, A; Brasse, D; Etienne-Selloum, N; Schini-Kerth, VB; Schleiffer, R; Vanhoutte, PM; Walter, A | 1 |
| Aihara, K; Akaike, M; Azuma, H; Ikeda, Y; Ise, T; Ishikawa, K; Iwase, T; Kato, S; Matsumoto, T; Sato, T; Sumitomo, Y; Yagi, S; Yoshida, S | 1 |
| Bian, ZY; Cai, J; Ghosh, AK; Li, A; Li, H; Shen, DF; Tang, QZ; Yan, L; Yang, L; Yang, Q; Yang, XC; Yi, FF | 1 |
| Elased, KM; Irigoyen, MC; Kanakamedala, K; Morris, M; Senador, D | 1 |
| Curtis, MJ; Stables, CL | 1 |
| Algür, M; Cheng, C; de Crom, R; Krams, R; Tempel, D; van Damme, L; van Haperen, R | 1 |
| Deng, YL; Li, CY; Sun, BH | 1 |
| Navar, LG; Seth, DM; Shao, W | 1 |
| Ferrario, C; Habibi, J; Hayden, MR; Lastra, G; Manrique, C; Patel, K; Rehmer, J; Sowers, JR; Whaley-Connell, AT | 1 |
| Cassis, LA; Charnigo, R; Daugherty, A; Gupte, M; Howatt, DA; Rateri, DL; Thayer, S; Zhang, X | 1 |
| Fiebeler, A; Haller, H; Luft, FC; Menne, J; Mervaala, EM; Muller, DN; Park, JK | 1 |
| Jin, LM | 1 |
| Fujikura, K; Konofagou, EE; Luo, J; Tilson, MD; Tyrie, LS | 1 |
| Brook, RD; Chen, LC; Mikolaj, M; Rajagopalan, S; Sun, Q; Wang, A; Xu, X; Ying, Z; Yue, P; Zhong, M | 1 |
| Ishida, K; Kamata, K; Kobayashi, T; Matsumoto, T; Nakayama, N | 1 |
| Bagi, Z; Edes, I; Erdei, N; Feher, A; Henrion, D; Kaley, G; Koller, A; Papp, Z; Rutkai, I | 1 |
| Hirooka, Y; Ito, K; Sunagawa, K | 1 |
| Bataller, R; Ching-A-Sue, G; Colmenero, J; Eliopoulos, AG; Jonsson, JR; Manas, D; Mann, DA; Oakley, F; Teoh, V; Watson, MR | 1 |
| Drummond, HA; Granger, JP; Jernigan, NL; LaMarca, B; Speed, J | 1 |
| Phisitkul, S | 1 |
| Bjurgert, E; Cuthbertson, A; Hofstra, L; Indrevoll, B; Kindberg, GM; Krasieva, TB; Lovhaug, D; Narula, J; Narula, N; Petersen, LB; Petrov, AD; Reutelingsperger, CP; Solbakken, M; Tromberg, BJ; Vannan, MA; Verjans, JW | 1 |
| Helle, F; Hultström, M; Iversen, BM | 1 |
| Budge, H; Fainberg, HP; Gardner, DS; Harvey, E; Sharkey, D; Symonds, ME; Wilson, V | 1 |
| Cheng, J; Crumpacker, CS; Jin, Z; Ke, Q; Kocher, O; Morgan, JP; Wang, H; Zhang, J | 1 |
| Chen, WQ; Guo, T; Zhang, C; Zhang, Y; Zhao, YX | 1 |
| Gou, W; Ji, Y; Liu, J; Liu, N; Wang, Z | 1 |
| Fukai, T | 1 |
| Anrather, J; Capone, C; Iadecola, C; Milner, TA | 1 |
| Bauersachs, J; Ertl, G; Fraccarollo, D; Galuppo, P; Hansen, JM; Jones, DP; Widder, JD | 1 |
| Adams, JM; Bardgett, ME; Stocker, SD | 1 |
| Cockerill, GW; Deb, R; Dunkley, M; Gaze, D; Gnaneswaran, Y; Howe, F; Jones, A; Loftus, IM; Nasr, H; Thompson, MM; Torsney, E | 1 |
| Chen, BY; Chen, JK; Feng, HS; Huang, XJ; Liu, LB; Qu, P; Tie, R; Yu, J; Zhao, YF; Zhu, MZ; Zhu, XX | 1 |
| Granger, JP; Stec, DE; Vera, T | 1 |
| Balarini, CM; Cabral, AM; Meyrelles, SS; Pereira, TM; Silva, IV; Vasquez, EC | 1 |
| Cullen, B; Golledge, J; Moxon, JV; Nyara, M; Rush, C; Trollope, A | 1 |
| Bader, M; Bürgelová, M; Cervenka, L; Dvorák, P; Kramer, HJ; Malý, J; Opocenský, M; Thumová, M; Vanourková, Z; Zelízko, M | 1 |
| Bergmann, MW; de Windt, L; Dietz, R; Gehrke, C; Noack, C; Renger, A; van der Nagel, R; Zafiriou, MP; Zelarayan, L | 1 |
| Khachigian, LM; Li, JM; Stocker, R; Tan, NY | 1 |
| Aravindhan, K; Bernard, RE; Boyle, RJ; Gardner, SD; Gough, PJ; Jucker, BM; Newman, MJ; Olzinski, AR; Turner, GH; Willette, RN | 1 |
| Choi, BH; Choi, JH; Hong, JT; Jang, MJ; Jeon, JH; Joo, SS; Kim, YB; Oh, KW; Park, D; Shin, S; Suh, KH | 1 |
| Anandan, SK; Chen, D; Cheng, Y; Gless, R; Mehra, U; Vincelette, J; Wang, YX; Webb, HK; Zhang, LN | 1 |
| Chung, AC; Huang, XR; Lan, HY; Yang, F | 1 |
| Balus, SF; Durand, MJ; Lombard, JH; McEwen, ST | 1 |
| Anegawa, T; Hirooka, Y; Ikeda, A; Imaizumi, T; Kai, H; Kajimoto, H; Kato, S; Koga, M; Kudo, H; Mifune, H; Mori, T; Takayama, N; Yasuoka, S | 1 |
| Li, YF; Patel, KP; Wang, W; Zheng, H | 1 |
| Fink, GD; Osborn, JW | 1 |
| Beasley, D; Galper, JB; Moulton, KS; Naggar, JC; Park, HJ; Welzig, CM; Zhang, Y | 1 |
| Frohlich, ED; Lacolley, P; Regnault, V; Safar, ME | 1 |
| Guo, F; Hay, M; Johnson, AK; Singh, M; Xue, B | 1 |
| Ahluwalia, A; Duchene, J; Hodgkinson, CP; Hu, Y; Kiechl, S; Laxton, RC; Leung, KY; López-Otín, C; Scotland, RS; Simpson, IA; Smith, K; Willeit, J; Xiao, Q; Xu, Q; Ye, S; Zhang, F; Zhang, Z | 1 |
| Ishii, M; Kubota, R; Matsushita, T; Morita, Y; Murohara, T; Numaguchi, Y; Okumura, K; Yamamoto, K | 1 |
| Guethe, LM; Juliano, MA; Martins, AR; Pelegrini-da-Silva, A; Prado, WA; Rosa, E | 1 |
| O'Rourke, ST; Qian, SY; Sun, C; Yao, F; Zhang, Q | 1 |
| Chen, S; Chen, Y; Li, G; Olson, JE; Sigmund, CD; Wang, J; Zhang, W | 1 |
| de Crom, R; Lehoux, S; Mees, B; Ramkhelawon, B; Rivas, D; Tedgui, A; Vilar, J | 1 |
| Chan, JY; Chan, SH; Chang, AY; Ho, YH; Wu, CA; Wu, KL | 1 |
| Begg, DP; Jois, M; Weisinger, RS | 1 |
| Bataller, R; Colmenero, J; De Minicis, S; Gwak, GY; Kluwe, J; Mencin, A; Osterreicher, CH; Pradere, JP; Schwabe, RF | 1 |
| Chaudhary, AK; Ely, D; Gopinathannair, R; Martins, JB; Xing, D; Zheng, W | 1 |
| Burmeister, MA; Davisson, RL; Guruju, MR; Peterson, JR; Sharma, RV; Stupinski, JA; Tian, X; Zhou, Y | 1 |
| Basu, R; Guo, D; Kassiri, Z; Liu, PP; Oudit, GY; Penninger, JM; Scholey, JW; Wang, X; Zhong, J | 1 |
| Hong, E; Villafaña, S | 1 |
| Cho, HS; Kim, WK; Lee, J; Park, S | 1 |
| Bivona, BJ; Chappell, MC; Harrison-Bernard, LM; Kobori, H; Lazartigues, E; Park, S; Seth, DM | 1 |
| Gonzalez-Villalobos, RA; Katsurada, A; Kim, C; Kobori, H; Navar, LG; Ohashi, N; Prieto, MC; Satou, R; Semprun-Prieto, LC; Upchurch, GM | 1 |
| Kagami, S; Kawachi, H; Kinoshita, Y; Kitamura, A; Kondo, S; Matsuura, S; Shimizu, M; Suga, K; Takamatsu, M; Tamaki, T; Urushihara, M; Yoshizumi, M | 1 |
| McLemore, GR; Ryan, MJ; Stec, DE; Storm, MV; Vera, T | 1 |
| Diez-Freire, C; Paton, JF; Polson, JW; Potts, JT; Raizada, MK; Sun, C; Zhang, Q; Zubcevic, J | 1 |
| Mallat, Z | 1 |
| Cowley, AW; Polichnowski, AJ | 1 |
| Born, W; Brain, SD; Clark, N; Fischer, JA; Husmann, K; Keeble, J; Liang, L; Poston, R; Pozsgai, G; Shah, A; Siow, R; Tam, CW | 1 |
| Imaizumi, T; Kai, H; Kajimoto, H; Kudo, H; Takayama, N; Yasuoka, S | 1 |
| Hashimoto, T; Kanematsu, M; Kanematsu, Y; Kurihara, C; Nuki, Y; Tsou, TL | 1 |
| Cao, CM; Cheng, H; Peng, W; Xiao, RP; Zhang, Y; Zheng, M; Zhu, W | 1 |
| Chakrabarti, S; Davidge, ST; Lekontseva, O; Peters, A | 1 |
| Bibevski, S; Fakhry, I; Mazgalev, TN; Popovic, ZB; Sica, DA; Van Wagoner, DR; Zhang, Y | 1 |
| Brasier, AR; Guo, DC; Ju, X; Lee, C; Lejeune, W; Milewicz, D; Recinos, A; Spratt, H; Sun, H; Tieu, BC; Tilton, RG | 1 |
| Ahishali, B; Arican, N; Bilgic, B; Elmas, I; Kalayci, R; Kaya, M; Küçük, M; Uzun, H | 1 |
| Lorenz, JN | 1 |
| Ding, L; Gao, YJ; Lee, RM; Lu, C; Su, LY | 1 |
| Bunker, AK; Laughlin, MH | 1 |
| Iliescu, R; Lohmeier, TE | 1 |
| Aravindhan, K; Bernard, RE; Cornejo, CA; Goodman, KB; Gough, PJ; Hoang, B; Jucker, BM; Karr, H; Macphee, CH; Olzinski, AR; Qin, P; Ringenberg, MA; Sehon, CA; Turner, GH; Willette, RN | 1 |
| Barrett, EJ; Cao, W; Carey, RM; Chai, W; Liu, J; Liu, Z; Wang, W | 1 |
| Gordon, FJ; Guzik, TJ; Harrison, DG; Lob, HE; Marvar, PJ; McCann, LA; Sharma, S; Weyand, C | 1 |
| Bader, M; Diedrich, A; Goncalves, AC; Gross, V; Hilzendeger, AM; Pesquero, JB; Plehm, R | 1 |
| Chander, PN; Charney, DN; Ding, G; Kumar, D; Singhal, PC; Vallabu, S; Yadav, A | 1 |
| Agunanne, E; Horvat, D; Puschett, JB; Uddin, MN | 1 |
| Anderson, ME; Grumbach, IM; Gupta, AK; Li, H; Li, W; Mohler, PJ | 1 |
| Danser, AH; Moltzer, E; van Esch, JH; van Veghel, R; Verkuil, AV | 1 |
| Loria, AS; Pollock, DM; Pollock, JS | 1 |
| Border, WA; Huang, Y; Noble, NA; Zhang, J | 1 |
| Brosnihan, KB; Chappell, MC; Dechend, R; Hering, L; Herse, F | 1 |
| Blinder, Y; Guzik, TJ; Harrison, DG; Iwakura, Y; Lob, HE; Madhur, MS; McCann, LA | 1 |
| Fogo, AB; Han, JY; Kon, V; Ma, LJ; Naito, T; Tang, Y; Yang, H; Zuo, Y | 1 |
| Finch, M; Gao, L; Li, Y; Schultz, HD; Smith, LM; Wang, W; Wang, WZ; Zucker, IH | 1 |
| Brower, GL; Janicki, JS; Levick, SP; Murray, DB | 1 |
| Heymans, S; Hofstra, L; Kubben, N; Leenders, JJ; Pinto, YM; Schellings, MW; Swinnen, M; van Almen, GC; van Leeuwen, RE; Vanhoutte, D | 1 |
| Cheng, PW; Cheng, WH; Ho, WY; Hsiao, M; Lu, PJ; Tseng, CJ; Tung, CS | 1 |
| Brinks, HL; Eckhart, AD | 1 |
| Arranz, C; Dominici, FP; Giani, JF; Mayer, MA; Muñoz, MC; Taira, CA; Toblli, JE; Turyn, D; Veiras, LC | 1 |
| Audoly, LP; Coffman, TM; Facemire, CS; Griffiths, R; Koller, BH | 1 |
| Diz, DI; Garcia-Espinosa, MA; Link, K; Olson, J; Robbins, ME; Shaltout, HA; Westwood, BM | 1 |
| Biala, A; Eriksson, O; Finckenberg, P; Kaheinen, P; Lapatto, R; Lempiäinen, J; Louhelainen, M; Luft, FC; Martonen, E; Mattila, I; Merasto, S; Mervaala, E; Muller, DN; Oresic, M | 1 |
| Chadipiralla, K; Raij, L; Schulman, IH; Zhou, MS | 1 |
| Kato, K; Lengfeld, J; Liu, B; Morgan, S; Yamanouchi, D; Zhang, F | 1 |
| Cassis, LA; Charo, IF; Daugherty, A; Howatt, DA; Owens, AP; Rateri, DL | 1 |
| Ahmad, S; Davidoff, KS; Desjardins, DM; Ewen, EP; Gavras, H; Kielbasa, OM; Mathew, M; McCalmon, SA; Naya, FJ; Ohashi, K; Sato, K; Snyder, CM; Walsh, K | 1 |
| Alonso, F; Haefliger, JA; Krattinger, N; Mazzolai, L; Meda, P; Simon, A; Waeber, G | 1 |
| Kitazato, KT; Nagahiro, S; Satomi, J; Tada, Y; Tamura, T; Yagi, K | 1 |
| Cervenka, L; Kopkan, L | 1 |
| Almeida, J; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Nadu, AP; Santos, RA; Vieira, RL | 1 |
| Rodriguez-Iturbe, B | 1 |
| Ali, ZA; Anderson, JA; Ashley, EA; Chun, HJ; Cox, CM; Kojima, Y; Krieg, PA; Kundu, RK; Leeper, NJ; Quertermous, T | 1 |
| Gopal, K; Jahan, P; Kumar, K; Kumar, MJ; Nandini, R | 1 |
| Kocsis, A; Kollai, M; Monos, E; Nádasy, GL; Székács, B; Szekeres, M; Várbíró, S | 1 |
| Bosch, RJ; Izquierdo, A; López-Luna, P; Ortega, A; Romero, M | 1 |
| Chudakov, DM; Guo, F; Kasparov, S; Lane, S; Liu, B; Paton, JF; Souslova, EA; Tang, F | 1 |
| Cook, AK; Fuller, BS; Guan, Z; Inscho, EW; Pollock, JS; Yamamoto, T | 1 |
| Han, DW; Jin, LW; Liu, WN; Ren, XX; Zhang, LF; Zhu, J | 1 |
| Fox, DA; Kashihara, N; Morita, Y; Sakuta, T; Satoh, M | 1 |
| Chang, EI; Ikonomidis, JS; Jones, JA; Koval, C; Sheats, N; Spinale, FG; Stroud, RE; Zavadzkas, JA | 1 |
| Cao, G; Della Penna, SL; Fernández, BE; Gorzalczany, S; Pandolfo, M; Rosón, MI; Toblli, JE | 1 |
| Batifoulier-Yiannikouris, F; Cassis, LA; Daugherty, A; Police, SB; Putnam, K; Thatcher, S | 1 |
| Chisolm, GM; Eagleton, MJ; Graham, LM; Liao, M; Parine, B; Xu, J | 1 |
| An, J; Chen, L; Chen, YJ; Han, SX; He, GM; Ning, YY; Wang, T; Wen, FQ; Xu, D; Yang, T; Zhang, SF; Zhang, XH | 1 |
| Burns, KD; Dilauro, M; Genest, D; Robertson, SJ; Zimpelmann, J | 1 |
| Chen, BL; Cook, JL; Navar, LG; Re, RN; Redding, KM; Seth, DM; Sigmund, CD; Singh, A; Tang, WW | 1 |
| Dell, KM; Goto, M; Hoxha, N; Osman, R; Wells, RG; Wen, J | 1 |
| Cowley, AW; Jin, C; Polichnowski, AJ; Yang, C | 1 |
| Neuschwander-Tetri, BA; Oshima, K; Talkad, V; Ulmasov, B; Xu, Z | 1 |
| Murakami, M; Nakagiri, A; Sunamoto, M; Takeuchi, K | 1 |
| Casley, D; Gaspari, TA; Tesanovic, S; Vinh, A; Widdop, RE | 1 |
| Berké, B; Imam, G; Kerim, P; Moore, N; Tohti, I; Umar, A; Yimin, W | 1 |
| Choke, E; Cockerill, GW; Dawson, J; Howe, F; Loftus, IM; Thompson, MM; Wilson, WR | 1 |
| Badillo, FH; González-Cortazar, M; Herrera-Ruiz, M; Jiménez-Ferrer, E; Tortoriello, J | 1 |
| Brouwers, S; Dupont, AG | 1 |
| Dai, HY; Deng, BP; Dong, B; Gao, F; Jiang, H; Liu, B; Liu, CX; Liu, DS; Liu, YF; Lu, XT; Pan, CM; Qiao, Y; Qu, X; Song, HD; Wang, LC; Yin, HQ; Yu, QT; Zhang, L; Zhang, MX; Zhang, YH; Zhao, YX | 1 |
| Abidin, N; Choudhury, R; Garratt, CJ; Hall, MC; Kirubakaran, S; Peters, NS | 1 |
| Geffner, JR; Nahmod, KA; Walther, T | 1 |
| Gai, Y; Gao, W; Li, Z; Liu, F; Liu, X; Xu, M; Zhang, Y | 1 |
| Cai, WF; Hu, ZW; Lv, XX; Ma, YG; Wang, QQ; Wang, XX; Wang, ZY; Xin, BM; Yan, HM; Yan, J; Yang, HZ; Zhang, XW | 1 |
| Angus, JA; Korner, PI; Wright, CE | 1 |
| Dimaio, JM; Gerard, RD; Kinoshita, H; Kuwahara, K; Olson, EN; Richardson, JA; Sadek, H; Small, EM; Sutherland, LB; Thatcher, JE | 1 |
| Gordon, FJ; Guzik, TJ; Harrison, DG; Lob, HE; Marvar, PJ; McCann, LA; Thabet, SR; Weyand, C | 1 |
| Bers, DM; Blatter, LA; Bodi, I; DeSantiago, J; Domeier, TL; Lorenz, JN; Maillet, M; Mikoshiba, K; Molkentin, JD; Nakayama, H | 1 |
| Lazartigues, E | 1 |
| Durand, MJ; Lombard, JH; Raffai, G; Weinberg, BD | 1 |
| Fukushima, K; Kagota, S; Kunitomo, M; Mori, H; Nakamura, K; Nejime, N; Shinozuka, K; Sugimura, K; Tada, Y; Umetani, K | 1 |
| Appelhoff, RJ; Endre, ZH; Findon, G; Hill, JV | 1 |
| Cao, CS; Huang, L; Xiong, HW; Yang, JB; Yin, Q; Zhan, Z | 1 |
| Cervenka, L; Husková, Z; Kramer, HJ; Vaněčková, I; Vaňourková, Z | 1 |
| Cervenka, L; Husková, Z; Kramer, HJ; Kujal, P; Mrázová, I; Rakusan, D; Thumová, M; Vanecková, I; Vanourková, Z; Vernerová, Z | 1 |
| Asagami, T; Dalman, RL; Dua, MM; Miyama, N; Schultz, GM; Sho, E; Sho, M; Yeung, JJ | 1 |
| Fujii, M; Inoguchi, T; Kobayashi, K; Maeda, Y; Sasaki, S; Takayanagi, R; Zheng, J | 1 |
| Chen, A; Chen, Y; Haywood, JR; Morris, M; Northcott, CA; Watts, S | 1 |
| Hara, T; Hitomi, H; Ihara, G; Ito, S; Kiyomoto, H; Kobori, H; Kohno, M; Mori, T; Nagai, Y; Nakano, D; Nishiyama, A; Ohashi, N; Pelisch, N | 1 |
| Abu-Taha, M; Cerda-Nicolas, JM; Cortijo, J; Estañ, L; Hermenegildo, C; Issekutz, AC; Morcillo, EJ; Orallo, F; Piqueras, L; Rius, C; Sanz, MJ | 1 |
| Casarini, DE; Coelho, MS; Ferreira, DN; Furukawa, LN; Heimann, JC; Katayama, IA; Oliveira, IB; Rosa, KT | 1 |
| Huusko, J; Ruskoaho, H; Rysä, J; Serpi, R; Tenhunen, O; Tolonen, AM; Ylä-Herttuala, S | 1 |
| Chen, R; Eisner, C; Hu, X; Huang, Y; Kopp, JB; Leelahavanichkul, A; Mizel, D; Schnermann, J; Star, RA; Wright, EC; Yan, Q; Yuen, PS; Zhou, H | 1 |
| Dell, KM; Goto, M; Hoxha, N; Osman, R | 1 |
| Dai, W; He, W; Jiang, J; Kong, W; Shang, G; Wang, Y | 1 |
| Biala, A; Finckenberg, P; Kaheinen, P; Levijoki, J; Louhelainen, M; Luft, FC; Martonen, E; Merasto, S; Mervaala, E; Muller, DN | 1 |
| Ghee, JY; Han, DH; Kim, S; Kobori, H; Kuro-o, M; Ohashi, N; Piao, S; Song, JH; Yang, CW; Yoon, HE | 1 |
| Danser, AH | 1 |
| Carretero, OA; Liao, TD; Liu, TS; Peng, H; Reudelhuber, TL; Shesely, EG; Xu, J; Yang, JJ; Yang, XP | 1 |
| Abraham, NG; Cao, J; Germinario, L; Inoue, K; Kappas, A; Quilley, J; Rezzani, R; Rodella, L; Sodhi, K; Stec, DE; Vanella, L | 1 |
| Czabanka, M; Eklund, L; Heljasvaara, R; Ilves, M; Janmey, P; Kerkelä, R; Leskinen, H; Peuhkurinen, K; Pihlajaniemi, T; Piuhola, J; Rasi, K; Ruskoaho, H; Rysä, J; Sormunen, R; Vajkoczy, P; Vuolteenaho, O | 1 |
| Anand-Srivastava, MB; Lévesque, LO; Li, Y | 1 |
| Lin, F; Yang, X | 1 |
| Berges, A; Lebrun, S; Lietz, M; Stolle, K; Wallerath, T | 1 |
| Baker, KM; Choudhary, R; Guleria, RS; Pan, J; Tanaka, T | 1 |
| da Silva, AQ; Fontes, MA; Kanagy, NL | 1 |
| Ahn, SY; Ahn, YM; Chung, JH; Kang, SW; Kim, SD; Kim, SK; Lee, BC; Lee, SH | 1 |
| Arribas, I; Bosch, RJ; Bover, J; Esbrit, P; Izquierdo, A; Ortega, A | 1 |
| Ding, Y; Li, YL; Schultz, HD | 1 |
| Červenka, L; Hammock, BD; Honetschlägerová, Z; Husková, Z; Hwang, SH; Imig, JD; Kopkan, L; Kramer, HJ; Sporková, A; Tsai, HJ; Vaňourková, Z | 1 |
| Arthur, HM; Borthwick, GM; Watkins, SJ | 1 |
| CHEN, J; DENG, G; JIN, H; JU, SH; WANG, ZJ; WEN, S; YAO, YY; ZHAO, R | 1 |
| Braga, AN; de Paula, WX; Denadai, AM; Santoro, MM; Santos, RA; Sinisterra, RD | 1 |
| Ge, J; Gong, H; Jiang, G; Li, L; Lin, L; Ye, Y; Zhang, G; Zhou, N; Zou, Y | 1 |
| Hashimoto, T; Kanematsu, M; Kanematsu, Y; Kurihara, C; Lawton, MT; Liang, EI; Nuki, Y; Tada, Y; Tsou, TL; van Rooijen, N; Young, WL | 1 |
| Bernstein, KE; Billet, S; Fuchs, S; Gonzalez-Villalobos, RA; Kim, C; Navar, LG; Satou, R | 1 |
| Al Ghouleh, I; Cascino, T; Csanyi, G; Haurani, MJ; Montezano, AC; Pagano, PJ; Touyz, RM | 1 |
| Hennessy, A; Makris, A; Sunderland, N | 1 |
| Chen, CX; Gao, JP; Gu, WL; Lv, J; Wan, Y; Wu, Q | 1 |
| Chen, WY; Dai, G; Leng, XY; Li, CL; Sun, XT; Tang, LL; Zeng, WT | 1 |
| Al-Saad, S; Aljabri, MB; Andreasen, TV; Höper, AC; Lindal, S; Lund, T; Ytrehus, K | 1 |
| Chen, X; Ji, ZZ; Li, SL; Wu, T; Zhang, XW | 1 |
| Abdellatif, M; Ago, T; Sadoshima, J; Yang, Y; Zhai, P | 1 |
| Chrissobolis, S; Drummond, GR; Kemp-Harper, BK; Miller, AA; Sobey, CG | 1 |
| Botros, FT; Casarini, DE; Feng, Y; Fernandes, FB; González-Villalobos, RA; Kobori, H; Lara, LS; Martin, VL; Navar, LG; Pagán, J; Prieto, MC; Satou, R | 1 |
| Aavula, BR; Anandan, SK; Cases, S; Chen, D; Cheng, Y; Do, ZN; Gless, R; Hammock, BD; Jones, PD; MacIntyre, DE; Mehra, U; Patel, DV; Sabry, J; Tran, V; Vincelette, J; Wang, YX; Waszczuk, J; Webb, HK; Whitcomb, R; White, K; Wong, KR; Zhang, LN | 1 |
| Cassis, LA; Daugherty, A; Gurley, SB; Howatt, DA; Lu, H; Thatcher, SE; Zhang, X | 1 |
| Gerszten, RE; Keliher, E; Leuschner, F; Marinelli, B; Nahrendorf, M; Pittet, MJ; Robbins, CS; Swirski, FK; Weissleder, R | 1 |
| Balakrishnan, A; Cassis, LA; Charnigo, R; Daugherty, A; Howatt, DA; Moorleghen, JJ; Owens, AP; Poduri, A; Rateri, DL; Subramanian, V | 1 |
| Barisoni, L; Birbaumer, L; Bowling, B; Burch, J; Byrd, A; Eckel, J; Finch, EA; Gbadegesin, R; Hall, G; Homstad, A; Lavin, PJ; Mukerji, N; Rosenberg, P; Sparks, M; Winn, MP; Wu, G; Zhang, ZS | 1 |
| Li, Y; Liu, N; Ren, L; Sheng, Z; Tang, R; Zhi, H | 1 |
| Han, B; He, Y; Ma, J; Pan, Y; Peng, T; Wang, Y; Wei, M; Xin, P; Zhu, W | 1 |
| Acres, OW; Kobori, H; Miyata, K; Ohashi, N; Satou, R; Urushihara, M | 1 |
| Fitzgerald, RS | 1 |
| Basu, R; Bodiga, S; Guo, D; Holland, SM; Kassiri, Z; Liu, GC; Lo, J; Oudit, GY; Penninger, JM; Scholey, JW; Wang, W; Zhong, JC | 1 |
| Bai, Y; Cao, Z; Cheng, G; Hu, C; Li, Y; Peng, J; Shi, R; Yang, T; Yuan, Q; Zhang, G | 1 |
| Sun, H; Wang, Y | 1 |
| Cook, JL; Li, XC; Rubera, I; Tauc, M; Zhang, F; Zhuo, JL | 1 |
| Au, CL; Gollasch, M; Huang, Y; Lau, CW; Ng, CF; Ng, SS; Wong, SL; Wong, WT; Xu, A; Yao, X | 1 |
| Berk, BC; Blaxall, BC; Cui, Z; Jaffré, F; Lu, Y; Menon, P; Mohan, A; Nigro, P; O'Dell, MR; Oikawa, M; Satoh, K; Soe, NN; Yan, C; Zeidan, A | 1 |
| Casarini, DE; Cunha, T; Flues, K; Irigoyen, MC; Moraes-Silva, I; Moreira, ED; Mostarda, C; Paulini, J; Piratello, AC; Salemi, V; Sirvente, R; Souza, PR | 1 |
| Gao, J; Gao, XY; Han, Y; Shi, Z; Yuan, N; Zhang, SJ; Zhou, YB; Zhu, GQ | 1 |
| Baylis, C; Cardounel, AJ; Grant, MB; Jarajapu, YP; Kasahara, H; Kearns, PN; Kirabo, A; Oh, SP; Sasser, JM; Sayeski, PP; Wagner, KU | 1 |
| Howard, CG; Mitchell, KD; Mullins, JJ | 1 |
| Harrison-Bernard, LM | 1 |
| Dong, XR; Hoglund, VJ; Majesky, MW | 1 |
| Borde, P; Kasture, S; Mohan, M | 1 |
| Cai, H; Cao, SP; Gu, N; Qian, CF; Song, YH; Zhao, ZM | 1 |
| Belmokhtar, K; Bonnet, P; Eder, V; Khamis, G; Machet, MC; Vourc'h, P; Worou, ME | 1 |
| Brandes, RP; Fischer, AS; Geisslinger, G; Maier, TJ; Mieth, A; Paulke, A; Pellowska, M; Popescu, L; Revermann, M; Schermuly, RT; Schubert-Zsilavecz, M; Steinhilber, D; Steri, R; Wurglics, M | 1 |
| Kasahara, H; Kirabo, A; Oh, SP; Sayeski, PP; Wagner, KU | 1 |
| Cai, J; Li, X; Lu, X; Niu, K; Xin, W | 1 |
| Arnold, AC; Diz, DI; Gilliam-Davis, S; Kock, ND; Shaltout, HA | 1 |
| Boone, M; Galiñanes, EL; Martinez-Lemus, LA; Zhao, G | 1 |
| Bobadilla Lugo, RA; Fernandez-Vallín, E; Lopez Sanchez, P; Velazquez-Roman, JA; Villafaña, S | 1 |
| Blinder, Y; Chen, W; Funt, SA; Harrison, DG; Iwakura, Y; Li, L; Lob, HE; Madhur, MS; Quyyumi, AA; Rahman, A; Vinh, A | 1 |
| Aziz, H; Bedja, D; Chen, Y; Dietz, HC; Doyle, JJ; Habashi, JP; Holm, TM; Judge, DP; Modiri, AN; Schoenhoff, F | 1 |
| Ali, BH; Fahim, MA; Nemmar, A; Subramaniyan, D; Zia, S | 1 |
| Auger, C; Jung, SH; Kim, KR; Lee, JO; Lee, SW; Oak, MH; Park, DH; Schini-Kerth, VB | 1 |
| Gleason, RL; Joseph, G; Maiellaro-Rafferty, K; Taylor, WR; Wan, W; Weiss, D | 1 |
| Bernstein, KE; Dolmatova, E; Dudley, SC; Duffy, HS; Gourdie, RG; Harris, BS; Iravanian, S; Jiao, Z; Lardin, HA; Liu, H; Sovari, AA; Witham, EA; Xiao, HD | 1 |
| Aro, J; Leskinen, H; Levijoki, J; Manninen, A; Moilanen, AM; Mustonen, E; Ruskoaho, H; Rysä, J; Serpi, R; Tokola, H; Vuolteenaho, O | 1 |
| Chen, J; Entman, ML; Lin, SC; Miao, Y; Taffet, GE; Wang, Y; Xu, J | 1 |
| Hong, CY; Hou, SM; Ko, WC; Lai, LP; Lee, CF; Lin, CH; Ong, ET; Tsai, CT | 1 |
| Dietz, HC; Lindsay, ME | 1 |
| Vaajanen, A; Vapaatalo, H | 1 |
| Becari, C; Oliveira, EB; Salgado, MC; Teixeira, FR | 1 |
| Cordasic, N; Daniel, C; Hartner, A; Heusinger-Ribeiro, J; Hilgers, KF; Klanke, B; Knier, B; Veelken, R | 1 |
| Fanelli, C; Fernandes, BH; Fujihara, CK; Machado, FG; Malheiros, DM; Okabe, C; Zatz, R | 1 |
| Essick, EE; Ghobrial, J; Ohashi, K; Ouchi, N; Pimentel, DR; Sam, F; Shibata, R; Wilson, RM | 1 |
| Brown, NJ | 1 |
| Bernier, NJ; Ellis, K; Montpetit, C; Perry, SF; Russell, J | 1 |
| Hirooka, Y; Hoka, S; Ito, K; Kishi, T; Nakagaki, T; Sunagawa, K | 1 |
| Hernández-Fonseca, JP; Mosquera, J; Muñoz, M; Pedreañez, A; Rincón, J; Viera, N | 1 |
| Dong, YF; Kataoka, K; Kim-Mitsuyama, S; Koibuchi, N; Nakamura, T; Nako, H; Ogawa, H; Tokutomi, Y; Toyama, K; Yamamoto, E; Yasuda, O | 1 |
| Arcaya, JL; Carrizo, E; Mosquera, J; Pedreañez, A; Peña, C; Rincón, J; Vargas, R; Viera, N | 1 |
| Bortz, PD; Halterman, JA; Kwon, HM; Wamhoff, BR; Zargham, R | 1 |
| Dorn, GW; Duan, X; Gold, JI; Koch, WJ; Matkovich, SJ; Zhang, Y | 1 |
| Horiguchi, N; Ichikawa, T; Izumi, T; Kakizaki, S; Kishimoto, K; Mori, M; Ohyama, T; Sato, K; Takagi, H; Yamazaki, Y | 1 |
| Chen, CM; Chou, HC; Jiang, JS; Lang, YD; Shih, CM; Wang, LF; Wu, MY | 1 |
| Cassis, LA; Daugherty, A; Lu, H | 1 |
| Al-Azawi, H; Banes-Berceli, AK; Brands, MW; Femminineo, D; Hill-Pyror, C; Proctor, D; Qu, H; Webb, RC | 1 |
| Galan, M; Kassan, M; Matrougui, K; Partyka, M; Trebak, M | 1 |
| Dell'Italia, LJ | 1 |
| Li, YF; Mehta, PP; Patel, KP; Sharma, NM; Zheng, H | 1 |
| Belatti, DA; Curry, PL; Gao, L; Kar, S; Zucker, IH | 1 |
| Cassis, LA; Daugherty, A; Poduri, A; Subramanian, V; Uchida, HA | 1 |
| Kang, KT; Loria, AS; Pollock, DM; Pollock, JS | 1 |
| Abbate, A; Dhaduk, R; Li, N; Li, PL; Van Tassell, BW; Wang, Z; Xia, M; Zhu, Q | 1 |
| Glover, PH; Iliescu, R; Mathis, KW; Ray, WH; Ryan, MJ; Venegas-Pont, M | 1 |
| Abraham, T; Ang, LS; Bleackley, RC; Boivin, WA; Carmine-Simmen, K; Granville, DJ; McManus, BM; Williams, SJ; Zhao, H | 1 |
| Boon, RA; Brandes, RP; Dimmeler, S; Essers, J; Fischer, A; Hergenreider, E; Heydt, S; Horrevoets, AJ; Pilato, M; Rosenthal, N; Sciacca, S; Seeger, T; van Heijningen, P; Vinciguerra, M; Zeiher, AM | 1 |
| Hashizume, R; Narita, Y; Ueda, Y; Wagner, WR; Yamawaki-Ogata, A | 1 |
| Granger, DN; Kurmaeva, E; Ostanin, D; Russell, J; Senchenkova, EY | 1 |
| de Bruno, MP; Jerez, S; Karbiner, S; Scacchi, F; Sierra, L | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Nemoto, S; Taguchi, K | 1 |
| Chowdhury, MA; Dysko, RC; Fukuda, A; Sato, Y; Shedden, KA; Venkatareddy, MP; Wang, SQ; Wickman, LT; Wiggins, JE; Wiggins, RC | 1 |
| Fukui, A; Hara, M; Murozono, Y; Nagano-Torigoe, Y; Nakagawa, M; Ooie, T; Saikawa, T; Shinohara, T; Takahashi, N; Taniguchi, Y; Teshima, Y; Thuc, LC; Wakisaka, O; Yoshimatsu, H; Yufu, K | 1 |
| Cardinale, JP; Francis, J; Lazartigues, E; Sriramula, S | 1 |
| Cassis, LA; Curtiss, LK; Daugherty, A; Howatt, DA; Lu, H; Moore, KJ; Owens, AP; Rateri, DL; Tobias, PS | 1 |
| Chen, J; Chopp, M; Cui, X; Cui, Y; Liu, X; Lu, M; Roberts, C; Shehadah, A; Yan, T; Ye, X; Zacharek, A | 1 |
| Balakrishnan, A; Howatt, DA; Ijaz, T; Moorleghen, JJ; Subramanian, V; Uchida, HA | 1 |
| Fazio, S; Fogo, AB; Ichikawa, I; Kaseda, R; Kon, V; Linton, MF; Ma, LJ; Yamamoto, S; Yancey, PG; Zuo, Y | 1 |
| Banfalvi, A; Borok, Z; Buckley, ST; Crandall, ED; DeMaio, L; Dubourd, M; Ehrhardt, C; Flodby, P; Krishnaveni, MS; Minoo, P; Xing, Y; Zhou, B | 1 |
| Aritomi, S; Konda, T; Yoshimura, M | 1 |
| de Kloet, AD; Flak, JN; Herman, JP; Jones, K; Krause, EG; Reagan, LP; Sakai, RR; Scott, KA; Smeltzer, MD; Ulrich-Lai, YM; Wilson, SP; Woods, SC | 1 |
| Allahdadi, KJ; Choi, H; Tostes, RC; Webb, RC | 1 |
| Bellini, G; Bernardi, S; Fabris, B; Fallo, F; Johnston, CI; Losurdo, P; Monticone, S; Thomas, MC; Tikellis, C; Toffoli, B; Veglio, F; Zennaro, C | 1 |
| Domińska, K; Drobnik, J; Ochędalski, T; Piastowska-Ciesielska, AW; Russell, JA; Zarzyńska, J | 1 |
| Ashraf, M; Bernard, LS; Davis, LE; Hashima, JN; Hohimer, AR; Rasanen, J; Sahn, DJ; Vuolteenaho, O | 1 |
| Berman, S; Chanimov, M; Efrati, S; Hamad, RA; Siman-Tov, Y; Weissgarten, J | 1 |
| Cartwright, EJ; Gui, J; Jin, J; Ke, Y; Lei, M; Liu, W; Naumann, R; Neyses, L; Prehar, S; Solaro, RJ; Taglieri, DM; Tsui, H; Ulm, S; Wang, X; Xiao, RP; Zi, M | 1 |
| Cai, H; Chalupsky, K; Chen, P; Galis, Z; Gao, L; Nguyen, A; Siu, KL; Weintraub, NL | 1 |
| Bernstein, KE; Bonini, MG; Dolmatova, E; Dudley, SC; Duffy, HS; Iravanian, S; Jiao, Z; Kumar, V; Liu, H; Sovari, AA; Wang, K; Zandieh, S | 1 |
| Barrick, CJ; Caron, KM; Dackor, RT; Lenhart, PM; Nagle, E | 1 |
| Furuhashi, M; Koyama, M; Maeda, T; Miura, T; Shimamoto, K; Tanaka, M; Togashi, N; Yoshida, H | 1 |
| Gul, R; Kim, SH; Kim, UH; Shawl, AI | 1 |
| Cassis, LA; Charnigo, R; Daugherty, A; Howatt, DA; Lu, H; Moorleghen, JJ; Subramanian, V; Wang, S | 1 |
| Gur, S; Hellstrom, WJ; Kadowitz, PJ | 1 |
| Baker, KM; Kumar, R; Thomas, CM; Yong, QC | 1 |
| Cook, JL; Re, RN | 1 |
| Anderson, LJ; Campbell, WB; Estes, AM; Fang, XR; Gonzalez, FJ; Jennings, BL; Malik, KU; Porter, J; Yaghini, FA | 1 |
| Carlstrom, M; Holland, S; Lai, EY; Luo, Z; Sandberg, K; Solis, G; Welch, WJ; Wellstein, A; Wilcox, CS | 1 |
| Azhar, M; Fouts, M; Haskett, D; Larson, D; Speicher, E; Utzinger, U; Vande Geest, J | 1 |
| Bernstein, KE; Blackwell, WL; Campbell, DJ; Chen, X; Fuchs, S; Gonzalez-Villalobos, RA; Lin, CX; Okwan-Duodu, D; Ong, FS; Shah, KH; Shen, XZ | 1 |
| Bruemmer, D; Daugherty, A; Lu, H; Rateri, DL | 1 |
| Johnson, AK; Johnson, RF; Xue, B; Zhang, Z | 1 |
| Falkenham, A; Lee, TD; Légaré, JF; Ma, I; Oxner, A; Sopel, M | 1 |
| Azuma, J; Chin, JT; Dalman, RL; Deng, A; Leeper, NJ; Maegdefessel, L; McConnell, MV; Merk, DR; Raaz, U; Raiesdana, A; Schoelmerich, AM; Spin, JM; Toh, R; Tsao, PS | 1 |
| Barrett, CJ; Guild, SJ; Malpas, SC; McBryde, FD | 1 |
| Furuta, K; Hongo, M; Ishizaka, N; Nagai, R; Saito, K; Sakamoto, A | 1 |
| Glascock, JJ; Habibi, J; Lorson, CL; Ma, L; Shababi, M; Sowers, JR | 1 |
| Bendall, JK; Carter, EE; Channon, KM; Crabtree, MJ; Douglas, G; Hale, AB; Tatham, AL | 1 |
| Araki, H; Araki, S; Chin-Kanasaki, M; Deji, N; Haneda, M; Isshiki, K; Kashiwagi, A; Koya, D; Kume, S; Maegawa, H; Nishiyama, A; Tanaka, Y; Uzu, T | 1 |
| Caligiuri, G; Clement, M; Fornasa, G; Gaston, AT; Groyer, E; Guedj, K; Kaveri, SV; Khallou-Laschet, J; Michel, JB; Morvan, M; Nicoletti, A; Tedgui, A | 1 |
| Bustelo, XR; Campuzano, V; Coustets, M; Francke, U; Menacho-Márquez, M; Nevado, J; Pérez-Jurado, LA; Sánchez-Rodríguez, C; Segura-Puimedon, M; Terrado, V | 1 |
| Chen, HY; Huang, XR; Lan, HY; Liu, Z; Penninger, JM | 1 |
| Adiarto, S; Emoto, N; Heiden, S; Nakayama, K; Vignon-Zellweger, N; Yagi, K; Yanagisawa, M | 1 |
| Anrather, J; Burmeister, MA; Cao, X; Davisson, RL; Guruju, MR; Iadecola, C; Peterson, JR; Wang, G; Young, CN | 1 |
| Hongo, M; Ishizaka, N; Nagai, R; Saito, K; Sakamoto, A | 1 |
| Fujisawa, G; Iwazu, Y; Kimura, M; Kobayashi, E; Kobayashi, T; Kusano, E; Masuda, T; Murakami, T; Muto, S; Nonaka-Sarukawa, M; Sasaki, N; Shimada, K; Shinohara, M; Watanabe, Y | 1 |
| Liang, ZS; Wang, LH; Yang, WX; Yu, SJ; Zhao, ZG | 1 |
| Liu, G; Sun, L; Zhang, Y; Zhuang, Y | 1 |
| Backs, J; Dierck, F; Frank, D; Frey, N; Katus, HA; Krebs, J; Kuhn, C; Lehmann, LH; Oehl, U; Will, R | 1 |
| Fang, F; Li, Y; Liu, N; Ma, G; Sheng, Z; Teng, GJ; Wang, Y; Wen, S; Yao, Y; Zhang, Y | 1 |
| Aoyama, Y; Fukaya, H; Izumi, T; Kiryu, M; Kishihara, J; Masaki, Y; Niwano, H; Niwano, S | 1 |
| Benkhoff, S; Brandes, RP; Dimmeler, S; Kosowski, J; Kruse, C; Luedike, P; Michaelis, UR; Mieth, A; Pliquett, R; Schröder, K; Shah, AM; Weissmann, N; Zhang, M | 1 |
| Aono, J; Higaki, J; Horiuchi, M; Inoue, K; Iwai, M; Nagai, T; Nishimura, K; Ogimoto, A; Okayama, H; Suzuki, J | 1 |
| Boustany-Kari, CM; Cassis, LA; Gupte, M; Karounos, M; Shoemaker, R; Thatcher, SE; Yiannikouris, F; Zhang, X | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K | 1 |
| Bapat, A; Fishbein, MC; Karagueuzian, HS; Lee, JH; Nguyen, TP; Sovari, AA; Weiss, JN | 1 |
| Becher, PM; Lindner, D; Miteva, K; Savvatis, K; Schmack, B; Schultheiss, HP; Tschöpe, C; Van Linthout, S; Westermann, D; Zietsch, C | 1 |
| Barrett, PQ; Bayliss, DA; Carey, RM; Guagliardo, NA; Hu, C; Schertz, EM; Tyson, DA; Yao, J | 1 |
| Brittian, KR; Cai, L; Chen, Q; Li, X; McClain, CJ; Prabhu, SD; Tan, Y; Yin, X; Zhou, Z | 1 |
| Asada, Y; Endo, GJ; Hatakeyama, K; Imamura, T; Kitamura, K; Matsuyama, M; Nagamachi, S; Nishimura, M; Onitsuka, T; Sakamoto, S; Sato, Y; Sekita, Y; Tsuruda, T; Yoshimura, K | 1 |
| Hamada, J; Kobara, M; Nakata, T; Noda, K; Shiraishi, T; Tanaka, T; Toba, H; Wang, J; Yoshifuji, Y | 1 |
| Collins, MJ; Holzapfel, GA; Humphrey, JD; Niklason, LE; Pierce, DM; Schriefl, AJ | 1 |
| Aoki, H; Fujita, T; Ichikawa, Y; Ishikawa, Y; Ishiwata, R; Jin, H; Jin, MH; Katayama, Y; Kato, Y; Kumagaya, S; Masuda, M; Minamisawa, S; Okumura, S; Sato, M; Sugimoto, Y; Suzuki, O; Suzuki, S; Yokoyama, U | 1 |
| Akhtar, S; Benter, IF; Dhaunsi, GS; Makki, BM; Qabazard, BA; Yousif, MH | 1 |
| Chuah, M; Creemers, EE; Hiller, M; Leenders, JJ; Pinto, YM; Swinnen, M; van der Made, I; Vandendriessche, T; Wijnen, WJ | 1 |
| Ertemi, H; Lau, DH; Mikhailidis, DP; Mumtaz, FH; Thompson, CS | 1 |
| Brown, NJ; Cohen, SE; Fogo, AB; Kim, HS; Luo, P; Luther, JM; Wang, Z | 1 |
| Campagnole-Santos, MJ; Fontes, MA; Guimaraes, PS; Santiago, NM; Santos, RA; Velloso, EP; Xavier, CH | 1 |
| Azibani, F; Chatziantoniou, C; Delcayre, C; Fazal, L; Samuel, JL | 1 |
| Chang, CJ; Dickinson, BC; Guo, Q; Hu, C; Ito, S; Lu, Y; Miyata, T; Mori, T; Nakamichi, T; Oba, I; Ogawa, S; Ohsaki, Y; Sato, E; Sato, H; Sun, Y; Yoneki, Y | 1 |
| Golledge, J; Krishna, SM; Moxon, JV; Norman, PE; Rush, C; Seto, SW; Walker, PJ | 1 |
| Beyer, AM; Fredrich, K; Lombard, JH; Raffai, G; Weinberg, B | 1 |
| Kusumoto, K | 1 |
| Baskaran, P; Beuve, A; Couloubaly, S; Crassous, PA; Durán, WN; Fioramonti, X; Huang, C; Kim, DD; Papapetropoulos, A; Zhou, Z | 1 |
| Chen, GF; Finney, L; Fukai, T; Kim, HW; Kohno, T; McKinney, RD; Ozumi, K; Sudhahar, V; Ushio-Fukai, M; Vogt, S | 1 |
| Engler, CW; Haack, KK; Papoutsi, E; Patel, KP; Pipinos, II; Zucker, IH | 1 |
| Aoki, H; Imaizumi, T; Kyogoku, S; Minami, T; Nagata, T; Oba, T; Ohmura, H; Ohshima, H; Sugi, Y; Yasukawa, H | 1 |
| Batlle, D; Evora, K; Garcia-Halpin, L; Gonzalez-Pacheco, FR; Poglitsch, M; Salem, M; Schuster, M; Wysocki, J; Ye, M | 1 |
| Kumar, U; McNeill, JH; Yuen, VG; Zhou, K | 1 |
| Alique, M; Benito-Martin, A; Egido, J; Lavoz, C; Mezzano, S; Ortiz, A; Rayego-Mateos, S; Rodrigues-Diez, R; Rodrigues-Diez, RR; Ruiz-Ortega, M | 1 |
| Kobori, H; Prieto, MC; Rands, VF; Seth, DM | 1 |
| Antonioli, L; Aydinoglu, F; Bernardini, N; Blandizzi, C; Colucci, R; Duranti, E; Fornai, M; Ippolito, C; Rugani, I; Segnani, C; Taddei, S; Virdis, A | 1 |
| Biondo-Simões, Mde L; Fávero, GM; Fernandes, D; Montemór Netto, MR; Olchanheski, LR; Ortolan, GL | 1 |
| Chen, J; Chen, S; Jiang, H; Xu, C; Xu, L; Yang, J; Zhang, J | 1 |
| Dai, Z; Huang, C; Wang, X; Xiao, J; Yu, S; Zhao, Q; Zou, M | 1 |
| Chen, H; Liu, L; Shi, GP; Shi, MA; Sukhova, GK; Sun, J; Zhang, J | 1 |
| Cao, X; Du, J; Guo, J; Li, H; Pan, L; Qin, Y; Shi, GP; Tang, C; Zhang, H; Zhang, Y | 1 |
| Abboud, FM; Ballas, ZK; Chapleau, MW; Harwani, SC; Legge, KL | 1 |
| Csiszar, K; Fong, SF; Joseph, G; O'Donnell, RE; Rafferty, K; Remus, EW; Taylor, WR; Weiss, D | 1 |
| Chen, XJ; He, B; Hu, LH; Jin, SX; Li, DD; Nie, P; Shen, LH; Yuan, W; Zhang, XK | 1 |
| Feng, J; Hu, J; Huang, Y; Kong, W; Liu, B; Liu, Z; Luo, H; Ma, K; Wang, X; Xie, J; Xu, Q; Zhan, S; Zhang, L; Zheng, J; Zhu, Y | 1 |
| Bujor, AM; Han, R; Stawski, L; Trojanowska, M | 1 |
| Busija, DW; Chappell, MC; Diz, DI; Gallagher, PE; Katakam, PV; Nautiyal, M; Tallant, EA | 1 |
| Ascione, R; Dominiczak, AF; Giannotta, M; Graham, D; Hendy, EB; Hewinson, J; Kasparov, S; Liu, B; McBride, F; Oliveira-Sales, EB; Paton, JF; Toward, M; Waki, H; Xu, H | 1 |
| Ardell, JL; Girasole, AE; Hardwick, JC; Negrotto, S; Ryan, SE; Southerland, EM | 1 |
| Deng, HW; Diao, TY; Gebru, YA; Gu, SS; Wu, SY; Zhang, Y | 1 |
| Gitlin, JM; Loftin, CD; Mukherjee, K | 1 |
| Hara, T; Hirata, K; Ishida, T; Okada, T; Rikitake, Y; Shinohara, M; Sun, L; Toh, R; Yamashita, T; Yasuda, T | 1 |
| Bencsik, P; Csonka, C; Csont, T; Ferdinandy, P; Kocsis, GF; Pálóczi, J; Pipicz, M; Sárközy, M; Varga, ZV | 1 |
| Bartlett, CS; Boyd, KL; Breyer, RM; Harris, RC; Zent, R | 1 |
| Asano, T; Fujita, T; Gao, J; Hasegawa, Y; Imai, J; Ishigaki, Y; Kaneko, K; Katagiri, H; Ogihara, T; Oka, Y; Saito, T; Shimosawa, T; Uno, K; Yamada, T | 1 |
| Baxter, BT; Charolidi, N; Cockerill, GW; Gaze, D; Laing, K; Meisinger, T; Petrova, S; Pirianov, G; Shoreim, A; Torsney, E; Xiong, W | 1 |
| Bezuhly, M; Esmon, CT; Falkenham, AG; Lee, TD; Légaré, JF; Liwski, RS; Rosin, NL; Sopel, MJ | 1 |
| Cassis, LA; Daugherty, A; Howatt, DA; Lu, H; Moorleghen, JJ; Rateri, DL; Xie, X | 1 |
| Han, Y; Li, Y; Liu, S; Sun, M; Tao, J; Tian, X; Yan, C; Zhang, J; Zhang, X | 1 |
| Cao, H; Hu, H; Huang, C; Huang, H; Li, H; Liu, Y; Qin, M; Wang, T | 1 |
| Kano, N; Koba, S; Watanabe, R; Watanabe, T | 1 |
| Beceiro, S; Cheng, J; Garg, V; Guggilam, A; Hans, CP; Huang, N; Koenig, SN; Kuivaniemi, H; Partida-Sánchez, S | 1 |
| Belanger, E; Duchemin, S; Ferland, G; Girouard, H; Wu, R | 1 |
| Müller-Fielitz, H; Raasch, W | 1 |
| Albertos, F; Blanes, JI; Company, C; González-Navarro, H; López-Ginés, C; Ludwig, A; Morcillo, EJ; Piqueras, L; Rius, C; Sanz, MJ | 1 |
| Adachi, T; Aikawa, N; Hori, S; Itoh, H; Kurihara, T; Okada, Y; Shimizu, H; Shimizu-Hirota, R; Shimoda, M; Weiss, SJ | 1 |
| Chen, B; Chen, Y; Dong, Y; Liu, D; Ma, Y; Xiong, Z; Yang, Y; Zhang, C | 1 |
| Chen, GC; Duan, SB; Liu, GL; Pan, P; Wang, P; Xu, XQ | 1 |
| Chu, Y; Faraci, FM; Heistad, DD; Miller, JD; Mitchell, IJ; Peña Silva, RA; Penninger, JM | 1 |
| Dibona, GF; Guron, G; Saeed, A | 1 |
| Loria, AS; Pollock, DM; Pollock, JS; Yamamoto, T | 1 |
| Chai, SY; De Bundel, D; Demaegdt, H; Gard, P; Loyens, E; Michotte, Y; Smolders, I; Vanderheyden, P | 1 |
| Guardiola, JJ; Sarmiento, X; Soler, M | 1 |
| Ge, J; Guo, J; Jiang, G; Li, L; Wang, S; Wu, J; You, J; Zou, Y | 1 |
| Hao, S; Kolodgie, FD; Mizrahi, B; Nguyen, BT; Ozaki, CK; Savion, N; Schneiderman, J; Tao, M; Virmani, R; Yu, P | 1 |
| Liu, SJ; Liu, WZ; Liu, Y; Tan, YZ; Yang, ZC; Zhang, X | 1 |
| Briet, M; Ebrahimian, T; Gonzalez, FJ; Kasal, DA; Leibowitz, A; Marchesi, C; Neves, MF; Offermanns, S; Paradis, P; Rautureau, Y; Rehman, A; Schiffrin, EL; Simeone, SM | 1 |
| Fujita, S; Hiroe, M; Hosotani, N; Imanaka-Yoshida, K; Ishizaka, N; Kitaura, Y; Kohda, Y; Nishioka, T; Otsuka, K; Shimojo, N; Tanaka, T; Terasaki, F; Yoshida, T | 1 |
| Granger, DN; Rodrigues, SF; Vital, SA | 1 |
| Dalman, RL; Fujimura, N; Glover, KJ; Hu, X; Iida, Y; Schultz, JR; Tanaka, H; Turner, CR; Wang, W; Xu, B; Xuan, H | 1 |
| Liang, B; Viollet, B; Wang, Q; Wang, S; Zhang, W; Zhu, Y; Zou, MH | 1 |
| Chang, JR; Chen, WJ; Qi, YF; Sui, YB; Tang, CS; Yin, XH; Yu, YR; Zhang, BH; Zhao, L | 1 |
| Fukahori, M; Hidaka, S; Inoue, N; Kawahara, S; Maruyama, M; Miura, N; Muguruma, M; Ohta, K; Yamada, K | 1 |
| Aihara, Y; Douhara, A; Fukui, H; Kaji, K; Kawaratani, H; Moriya, K; Namisaki, T; Noguchi, R; Shirai, Y; Yoshiji, H | 1 |
| Fang, X; Huang, DN; Huang, XL; Tan, JX; Wang, B | 1 |
| Anigbogu, CN; Brown, DR; Cassis, LA; Hoyt, RE; Randall, DC; Silcox, DL; Speakman, RO | 1 |
| Dalloz, M; Esposito, B; Mallat, Z; Pérez, N; Ponnuswamy, P; Romain, M; Taleb, S; Tedgui, A; Wang, Y; Yoshimura, A | 1 |
| DiBona, GF | 1 |
| Golledge, J; Jose, RJ; Körner, H; Moran, CS; Moxon, JV; Norman, PE; Roomberg, A; Rush, C | 1 |
| Alrob, OA; Harris, RA; Lopaschuk, GD; Mori, J; Oudit, GY; Wagg, CS | 1 |
| Chen, WW; Sun, HJ; Wang, JJ; Xiong, XQ; Zhang, F; Zhou, YB; Zhu, GQ | 1 |
| Andoh, TF; Bennett, WM; Isaac, J; Shihab, FS; Yi, H | 1 |
| Fukuda, N; Hu, WY; Kanmatsuse, K | 1 |
| Di Wang, H; Gopalakrishnan, V; Poduri, R; Shastri, S | 1 |
| Agabiti-Rosei, E; Bova, S; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rizzoni, D; Rossi, GP | 1 |
| Clagett, GP; Levi, M; Modrall, JG; Moe, O; Puttaparthi, K; Rogers, TE; Sadjadi, J; Turnage, RH; Welborn, MB | 1 |
| Angelini, A; Calvani, M; Dalla Libera, L; Della Barbera, M; Dona, M; Gobbo, V; Mosconi, L; Peluso, G; Ravara, B; Sandri, M; Vescovo, G | 1 |
| Fukunaga, M; Hayashi, A; Mifune, H; Miwa, K; Sakamoto, H; Shirouzu, K; Takamori, S; Terazaki, Y | 1 |
| Hayashi, K; Honda, M; Kubota, E; Matsuda, H; Okubo, K; Ozawa, Y; Saruta, T; Tokuyama, H | 1 |
| Asada, K; Jin, D; Kondo, K; Miyazaki, M; Nishimoto, M; Sakaguchi, M; Sasaki, S; Sawada, Y; Takai, S; Tsunemi, K; Yuda, A | 1 |
| Hattori, Y; Jesmin, S; Kitabatake, A; Mowa, CN; Sakuma, I | 1 |
| Ishizaka, N; Mitani, H; Mori, I; Nagai, R; Ohno, M; Saito, K; Sata, M; Usui, S; Yamazaki, I | 1 |
| Lai, WY; Liu, Y; Ouyang, P; Wang, MH; Xu, DL | 1 |
| Blanco, J; Egido, J; Esteban, V; Lorenzo, O; Mezzano, S; Ruiz-Ortega, M; Ruperez, M | 1 |
| Engeli, S; Gorzelniak, K; Janke, J; Luft, FC; Sharma, AM | 1 |
| Buczko, W; Kucharewicz, I; Matys, T; Pawlak, D; Pawlak, R | 1 |
| Amedeo Modesti, P; Bertolozzi, I; Boddi, M; Cecioni, I; Coppo, M; Formigli, L; Perna, AM; Polidori, G; Serneri, GG; Vanni, S; Zecchi-Orlandini, S | 1 |
| Chen, LY; Chen, PM; Li, P; Wang, SW | 1 |
| Campos, AH; Gibbons, GH; Pollman, MJ; Wang, W | 1 |
| De Keulenaer, GW; Lee, RT; MacGillivray, C; Rouleau, JL; Shimpo, M; Solomon, SD; Tominaga, S; Weinberg, EO | 1 |
| Kimura, B; Peng, J; Phillips, MI | 1 |
| Fujita, T; Goto, A; Kobayashi, N; Matsuoka, H; Onozato, ML; Tojo, A | 1 |
| Aebi, JD; Blum-Kaelin, D; Dechend, R; Dehmlow, H; Fiebeler, A; Haller, H; Löffler, BM; Luft, FC; Masur, S; Mullally, A; Muller, DN; Park, JK; Pilz, B | 1 |
| Li, X; Simard, JM | 1 |
| Hasebe, N; Ido, A; Ihara, T; Jin, YT; Kikuchi, K; Matsuhashi, H; Matsusaka, T; Natori, S | 1 |
| Taubman, MB | 1 |
| Boerrigter, G; Burnett, JC; Cataliotti, A; Costello-Boerrigter, LC; Harty, GJ; Lapp, H; Stasch, JP; Tsuruda, T | 1 |
| Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA | 1 |
| Eisner, GM; Felder, RA; Jose, PA | 1 |
| Belloni, AS; Kreutz, R; Nussdorfer, GG; Paul, M; Pessina, AC; Rossi, GP; Seccia, TM | 1 |
| Qui, XS; Sim, MK | 1 |
| Georgiev, V; Kambourova, T; Matsoukas, J; Pechlivanova, D; Tchekalarova, J | 1 |
| Morita, H; Sabbah, HN; Sharov, VG; Suzuki, G; Tanhehco, EJ; Todor, A | 1 |
| Bradley, WE; Dell'Italia, LJ; Lucchesi, PA; Powell, PC; Tallaj, J; Wei, CC | 1 |
| Chen, L; Tang, D; Xu, L; Zeng, J; Zhang, Y | 1 |
| Browne, AE; Chatterjee, K; Grossman, W; Karliner, JS; Lee, RJ; Parmley, WW; Sievers, RE; Zhu, BQ | 1 |
| Adams, MA; Angelis, E; Pak, BJ; Pang, SC; Sangaralingham, SJ; Smallegange, C; Tse, MY | 1 |
| de Champlain, J; El Midaoui, A; Laplante, MA; Wu, R | 1 |
| Isono, T; Kinoshita, M; Matsumoto, T; Ohnishi, M; Tsutamoto, T; Wada, A | 1 |
| Abukhalaf, IK; Bayorh, MA; Eatman, D; Ganafa, AA; Silvestrov, N; Socci, RR | 1 |
| Asano, T; Fujita, T; Ogihara, T | 1 |
| Kokkonen, JO; Kovanen, PT; Lindstedt, KA | 1 |
| Ardell, JL; Armour, JA; Dell'Italia, LJ; Dillon, AR; Hankes, GH; Holland, M; Lucchesi, PA; Rynders, P; Tallaj, J; Wei, CC | 1 |
| Liu, P; Matsuzaki, M; Moe, G; Naik, G; Nakamura, H; Takata, S; Umemoto, S | 1 |
| da Cunha, V; Deng, GG; Ho, JJ; Martin-McNulty, B; Rutledge, JC; Sullivan, ME; Tham, DM; Vergona, R; Wang, YX; Wilson, DW | 1 |
| Gironacci, M; Höcht, C; Opezzo, JA; Peña, C; Taira, CA | 1 |
| Asano, T; Ogihara, T | 1 |
| Md, S; Moochhala, SM; Siew-Yang, KL | 1 |
| Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH | 1 |
| Kaaja, R; Kokkonen, JO; Kovanen, PT; Kuoppala, A; Leskinen, HK; Liesmaa, I; Lindstedt, KA; Luodonpää, M; Ruskoaho, H; Rysä, J; Shiota, N | 1 |
| Bøtker, HE; Grove, E; Kimose, HH; Lund, S; Nielsen, TT; Randsbaek, F; Schmitz, O | 1 |
| Egashira, K; Hayashidani, S; Ikeuchi, M; Matsusaka, H; Shiomi, T; Suematsu, N; Takeshita, A; Tsutsui, H; Wen, J | 1 |
| Raij, L | 1 |
| Bendall, JK; Byrne, JA; Cave, AC; Gove, C; Grieve, DJ; Lambeth, JD; Li, JM; Shah, AM | 1 |
| Ichijo, H; Iwao, H; Izumi, Y; Izumiya, Y; Kim, S; Matsuzawa, A; Yoshida, K; Yoshiyama, M | 1 |
| Arend, A; Aunapuu, M; Ots, M; Pechter, U; Suuroja, T | 1 |
| Adler, GK; Jonasson, L; Martinez-Vasquez, D; Mukasa, K; Oestreicher, EM; Roubsanthisuk, W; Stone, JR | 1 |
| Inagaki, K; Iwanaga, Y; Izumi, T; Kihara, Y; Kita, T; Noma, A; Onozawa, Y; Sarai, N; Takenaka, H; Yoneda, T | 1 |
| Goens, MB; Kanagy, NL; Lund, AK; Walker, MK | 1 |
| Höcht, C; Opezzo, JA; Taira, CA | 1 |
| Cheng, ZJ; Finckenberg, P; Helkamaa, T; Lapatto, R; Louhelainen, M; Luft, FC; Männistö, P; Merasto, S; Mervaala, EM; Müller, DN; Rauhala, P; Reenilä, I | 1 |
| Angelos, MG; Little, CM; Paradis, NA | 1 |
| Horie, R; Kishimoto, C; Kwon, YW; Masutani, H; Nakamura, H; Ohira, A; Shioji, K; Tanito, M; Teratani, A; Yodoi, J | 1 |
| Cao, B; Feng, QH; Li, S; Li, XZ | 1 |
| Miyazaki, M | 1 |
| Cassis, LA; Daugherty, A | 1 |
| Bedigian, MP; Lu, L; Robinson, AD; Sun, Y; Weber, KT; Zhang, J | 1 |
| Kintscher, U; Law, RE; Lyon, CJ | 1 |
| Imaizumi, T; Kai, H; Kuwahara, F; Tokuda, K | 1 |
| Herrera-Acosta, J; Johnson, RJ; Long, DA; Price, KL | 1 |
| Jeppsson, B; Menger, MD; Riaz, AA; Sato, T; Schramm, R; Thorlacius, H; Wang, Y | 1 |
| Averill, DB; Brosnihan, KB; Ferrario, CM; Gallagher, PE; Ishiyama, Y; Tallant, EA | 1 |
| Agarwal, R; Campbell, RC; Warnock, DG | 1 |
| Brandes, RP; Busse, R; Geiger, H; Jung, O; Pedrazzini, T; Schreiber, JG | 1 |
| Chopra, K; Singh, D | 1 |
| Jochem, J | 1 |
| Amiri, F; Endemann, D; Neves, MF; Pu, Q; Rozen, R; Schiffrin, EL; Virdis, A | 1 |
| Catanzaro, DF; Chen, R; Hu, L; Laragh, JH; Merali, C; Sealey, JE; Shi, Y; Zhou, Y | 1 |
| Bruemmer, D; Collins, AR; Fishbein, MC; Hsueh, WA; Kim, S; Law, RE; Nicholas, S; Ross, RS; Schnee, J; Wang, W | 1 |
| Cassis, L; Daugherty, A | 1 |
| Cupesi, M; Gannon, J; Huang, H; Lee, RT; MacGillivray, C; Schulze, PC; Sylvan, JD; Yoshioka, J | 1 |
| Bonnet, S; Marthan, R; Pauvert, O; Rousseau, E; Savineau, JP | 1 |
| Bathgate, RA; Du, XJ; Layfield, SL; Mak, J; Mookerjee, I; Samuel, CS; Tregear, GW; Unemori, EN | 1 |
| Aizawa, Y; Kodama, M; Ma, M; Tachikawa, H; Takahashi, T; Watanabe, K; Wen, J; Yamaguchi, K | 1 |
| Azizi, M; Ménard, J | 2 |
| Heringer-Walther, S; Hohmann, C; Schultheiss, HP; Schulze, K; Steendijk, P; Tschöpe, C; Walther, T; Westermann, D | 1 |
| Ikeda, J; Kakudo, N; Nawata, J; Sakuma, M; Shirato, K; Sugimura, K; Suzuki, J; Wang, H | 1 |
| Campbell, RC | 1 |
| Li, YF; Patel, KP; Pliquett, RU; Schultz, HD; Wang, W; Zucker, IH | 1 |
| Eto, T; Hirano, S; Imamura, T; Ito, K; Kitamura, K; Kuwasako, K; Onitsuka, H; Yamakawa, H | 1 |
| Fujita, M; Hirata, A; Hori, M; Kitakaze, M; Liao, Y; Minamino, T; Nagamachi, Y; Nakatani, T; Ogawa, S; Okada, K; Ozawa, K; Takashima, S; Tomoike, H; Tsukamoto, O; Tsukamoto, Y; Yutani, C | 1 |
| Mallat, Z; Tedgui, A | 1 |
| Jin, H; Schwall, R; Wyss, JM; Yang, R | 1 |
| Boomsma, F; de Boer, RA; Flesch, M; Pinto, YM; Pokharel, S; Suurmeijer, AJ; van Gilst, WH; van Kampen, DA; van Veldhuisen, DJ | 1 |
| Bernstein, KE; Campbell, DJ; Capecchi, MR; Dudley, SC; Fuchs, S; Hoit, BD; Kasi, VS; Keshelava, G; Lewis, W; Xiao, HD; Zhao, H | 1 |
| Babaev, VR; Fazio, S; Fogo, A; Ichikawa, I; Kon, V; Linton, MF; Nobuhiko, A; Suganuma, E; Swift, LL | 1 |
| Jung, JY; Kim, WJ; Lee, JU | 1 |
| Brunner, F; Stessel, H; Wölkart, G | 1 |
| Bourassa, E; Falcón, BL; Katovich, MJ; Raizada, MK; Speth, RC; Stewart, JM; Sumners, C; Walter, G | 1 |
| Bahtyiar, G; Blendea, MC; Ferrario, CM; Jacobs, D; Kumar, P; McFarlane, SI; Ogrin, C; Sha, Q; Sowers, JR; Stas, S; Stump, CS | 1 |
| Shimizu, F | 1 |
| Dong, Y; Wang, XP; Wu, K; Wu, L; Zhang, R | 1 |
| Fujiwara, H; Nishigaki, K | 1 |
| Ekse, S; Fuskevåg, OM; Jalan, R; Nedredal, GI; Revhaug, A; Rose, C; Sen, S; Ytrebø, LM | 1 |
| Howard, LL; Mitchell, KD; Mullins, JJ; Patterson, ME | 1 |
| Liu, LM; Xun, J | 1 |
| Cruzado, MC; Miatello, RM; Risler, NR; Schiffrin, EL; Touyz, RM; Yao, G | 1 |
| Furihata, M; Kakinuma, Y; Karashima, T; Kudo, Y; Mori, Y; Morimoto, N; Sato, T; Shuin, T; Sugiura, T | 1 |
| Ioroi, T; Iwao, H; Izumi, Y; Izumiya, Y; Kim-Mitsuyama, S; Tanaka, T; Wanibuchi, H; Yamamoto, E; Zhan, Y | 1 |
| Beaucage, P; Moreau, P | 1 |
| Hattori, Y; Jesmin, S; Kitabatake, A; Miyauchi, T; Sakuma, I; Togashi, H; Yoshioka, M | 1 |
| Bouzeghrane, F; Reinhardt, DP; Reudelhuber, TL; Thibault, G | 1 |
| Couture, R; de Champlain, J; El Midaoui, A; Ongali, B; Petcu, M | 1 |
| Berr, SS; Bishop, SP; Bove, CM; Dimaria, JM; Epstein, FH; French, BA; Gilson, WD; Kramer, CM; Scott, CD; Yang, Z | 1 |
| Inoguchi, T; Kobayashi, K; Maeda, Y; Nakayama, M; Nawata, H; Sasaki, S; Sawada, F; Sonoda, N; Sonta, T; Sumimoto, H; Tsubouchi, H | 1 |
| Artero, ML; Bardelli, M; Burrell, LM; Candido, R; Carraro, M; Carretta, R; Cattin, MR; Davis, BJ; Fabris, B; Faccini, L; Fior, F; Zennaro, C | 1 |
| Hashikabe, Y; Hattori, Y; Kase, H; Nakanishi, N; Uchida, K | 1 |
| Li, GH; Wan, FS | 1 |
| Crackower, MA; Fukamizu, A; Guan, B; Guo, F; Hein, L; Huan, Y; Hui, CC; Imai, Y; Jiang, C; Kuba, K; Leong-Poi, H; Penninger, JM; Rao, S; Sarao, R; Slutsky, AS; Uhlig, S; Wada, T; Yang, P | 1 |
| Ayabe, N; Babaev, VR; Fazio, S; Fogo, AB; Ichikawa, I; Kon, V; Linton, MF; Tang, Y; Tanizawa, T | 1 |
| Crespo, MJ; Escobales, N | 2 |
| Cai, GJ; Shen, FM; Su, DF; Wang, DS; Xie, HH | 1 |
| Jang, Y; Lee, KS; Lee, S; Lim, HJ; Park, HY; Park, JH | 1 |
| Ferrebuz, A; Quiroz, Y; Rodríguez-Iturbe, B; Vanegas, V | 1 |
| Sun, Y; Weber, KT | 1 |
| Nagaria, AM; Reddy, S; Savin, VJ; Sharma, M; Sharma, R; Wiegmann, TB | 1 |
| Arimoto, T; Konta, T; Koyama, Y; Kubota, I; Niizeki, T; Shishido, T; Takahashi, H; Takeishi, Y | 1 |
| Chen, CM; Chou, HC; Hsu, HH; Wang, LF | 1 |
| Bontscho, J; Godes, M; Hocher, B; Joehren, O; Kupsch, E; Lai, E; Patzak, A; Richter, CM; Skalweit, A; Steege, A; Thöne-Reineke, C; Zimmermann, M | 1 |
| Aiqun, M; Geru, W; Tao, G; Xiaojun, B; Yutao, X | 1 |
| Armando, I; Bregonzio, C; Juorio, A; Macova, M; Pavel, J; Saavedra, JM; Sanchez-Lemus, E | 1 |
| Gaughan, C; Hashimoto, S; Kessler, SP; Schnermann, J; Sen, GC; Senanayake, PS | 1 |
| Liu, JL; Zucker, IH | 1 |
| Ma, R; Wang, W | 1 |
| Iwata, K; Jin, D; Katsuyama, M; Matsubara, H; Matsuki, M; Matsuno, K; Miyazaki, M; Takai, S; Yabe-Nishimura, C; Yamada, H; Yamanishi, K | 1 |
| Barnes, JL; Faulkner, JL; Springer, F; Szcykalski, LM | 1 |
| Cao, RH; Chen, SL; Du, YG; Lü, JY; Qiao, ZD; Wang, GP; Zhang, ZY | 1 |
| Alves da Silva, CG; Coimbra, TM; Costa, RS; de Jesus Soares, T; de Mattos Coelho, R | 1 |
| Ahn, Y; Bang, YJ; Epstein, JA; Jeong, MH; Kee, HJ; Kim, JK; Kim, KK; Kim, N; Kook, H; Nam, KI; Park, JE; Qian, YR; Sohn, IS; Yin, Z | 1 |
| Buczko, W; Chabielska, E; Domaniewski, T; Kamińska, M; Kramkowski, K; Mogielnicki, A; Stankiewicz, A | 1 |
| Hayashi, K; Homma, K; Kanda, T; Saruta, T; Sugano, N; Wakino, S | 1 |
| Cowley, AW; Ito, S; Mori, T | 1 |
| Kaul, CL; Ramarao, P; Srinivasan, K; Viswanad, B | 1 |
| Bobadilla Lugo, RA; López Sanchez, P; Pérez-Alvarez, VM; Robledo, LA | 1 |
| Banes-Berceli, AK; Brands, M; Caldwell, RW; Eaton, DC; Fulton, D; Ma, G; Marrero, MB; Shaw, S; Stern, DM | 1 |
| Altieri, PI; Crespo, MJ; Escobales, N | 1 |
| Matsumoto, M; Suzuki, S; Tahara, T; Taniguchi, K; Yabuki, A | 1 |
| Cordaillat, M; Jover, B; Mimran, A; Rugale, C | 1 |
| Bayorh, MA; Eatman, D; Mann, G; Walton, M | 1 |
| Aoki, R; Fukuyama, T; Orito, K; Shimizu, M; Tanaka, R; Yamane, Y | 1 |
| Majid, DS; Pech, V; Sikka, SC; Sindhu, RK; Vaziri, ND | 1 |
| Coelho, EF; Ferrari, MF; Fior-Chadi, DR; Maximino, JR | 1 |
| Backx, PH; Crackower, MA; Herzenberg, AM; Kassiri, Z; Khokha, R; Oudit, GY; Penninger, JM; Reich, H; Scholey, JW; Wong, D | 1 |
| Li, YL; Schultz, HD | 1 |
| Hirokoshi, K; Ichinose, K; Kitayama, H; Maeshima, Y; Makino, H; Sugiyama, H; Takazawa, Y; Wu, Y; Yamamoto, Y; Yamasaki, Y | 1 |
| Shoenfeld, Y; Tanay, A; Teplitsky, V | 1 |
| Bagi, Z; Hamar, P; Kardos, M; Koller, A | 1 |
| Catalán, V; Díez, J; Fortuño, A; Frühbeck, G; Gómez-Ambrosi, J; Rodríguez, A; Sáinz, N; Zalba, G | 1 |
| Argentino, DP; Dominici, FP; Muñoz, MC; Toblli, JE; Turyn, D | 1 |
| Choy, DF; da Cunha, V; Halks-Miller, M; Li, WW; Mahmoudi, M; Martin-McNulty, B; Schroeder, M; Sullivan, ME; Vergona, R; Vincelette, J; Wang, YX; Wilson, DW | 1 |
| Fukuda, N | 1 |
| Kaneko, S; Katsuno, T; Komuro, I; Kunieda, T; Minamino, T; Miyauchi, H; Nagai, T; Nishi, J; Okada, S; Orimo, M; Oyama, T; Takamura, M; Tateno, K | 1 |
| Hostetter, TH; Rosenberg, ME | 1 |
| Fink, GD; King, AJ | 1 |
| Comiter, CV; Escobar, C; Phull, H; Purves, T; Salkini, M | 1 |
| Achard, JM; Chapot, R; Faure, S; Javellaud, J; Oudart, N; Tallet, D | 1 |
| Almeida, AP; Araújo, CA; Caliari, MV; Ferreira, AJ; Jacoby, BA; Macedo, FA; Santos, RA; Silva, GA | 1 |
| Akasaka, T; Goto, M; Imanishi, T; Kobayashi, K; Kuroi, A; Mochizuki, S; Yoshida, K | 1 |
| Abriel, H; Boixel, C; Cefai, D; Domenighetti, AA; Pedrazzini, T | 1 |
| Gao, Y; Grobe, JL; Katovich, MJ; Li, H; Raizada, MK; Sumners, C | 1 |
| Chatziantoniou, C; Curat, CA; Dussaule, JC; Flamant, M; Placier, S; Rodenas, A; Vogel, WF | 1 |
| Bolton, TA; Grobe, JL; Katovich, MJ; Lingis, M; Machado, JM; Mecca, AP; Raizada, MK; Shenoy, V; Speth, RC | 1 |
| Cibulskyte, D; Frøkiaer, J; Hansen, HE; Hørlyck, A; Madsen, M; Marcussen, N; Mortensen, J; Pedersen, M | 1 |
| Elmarakby, AA; Imig, JD; Pollock, DM; Pollock, JS; Williams, JM | 1 |
| Arcaya, JL; Carrizo, E; Mosquera, J; Pedreanez, A | 1 |
| Prabhakar, S; Rosario, RF | 1 |
| Ambühl, PM; Bachmann, MF; Fulurija, A; Jennings, GT; Maurer, P; Müller, P; Nief, V; Nussberger, J; Pfister, T; Rettenbacher, M; Roubicek, K; Sabat, R; Schellekens, C; Sladko, K; Tissot, AC; Volk, HD; Wagner, F | 1 |
| Bell, TD; Brands, MW; Fleming, C; Janardhanan, R; Rojas, M; Springfield, V; Sturgis, LC | 1 |
| Urata, H | 1 |
| Bae, SS; Heo, HJ; Jung, KH; Kim, CD; Lee, JY; Lee, SJ; Lee, WS; Park, JY; Yun, MR | 1 |
| de Resende, MM; Greene, AS; Kriegel, AJ | 1 |
| Al-Saadi, N; Dechend, R; Feldt, S; Fiebeler, A; Fischer, R; Gapeljuk, A; Gratze, P; Haller, H; Luft, FC; Madwed, JB; Meiners, S; Muller, DN; Park, JK; Schirdewan, A; Shagdarsuren, E; Wellner, M | 1 |
| Griffin, AJ; Gupta, M; Kumbar, DH; Muangmingsuk, S; Ocampo, C; VanBergen, A | 1 |
| Gao, Y; Li, H; Matsuura, T; Raizada, MK; Sumners, C; Sun, C; Upchurch, PA | 1 |
| Aro, J; DeChâtel, R; Földes, G; Göoz, M; Lakó-Futó, Z; Leppäluoto, J; Papp, L; Ruskoaho, H; Sármán, B; Seres, L; Skoumal, R; Szokodi, I; Tóth, M; Vuolteenaho, O | 1 |
| Kamezaki, F; Koide, S; Nakashima, Y; Okazaki, M; Otsuji, Y; Ozumi, K; Sasaguri, Y; Takatsu, H; Tamura, M; Tanimoto, A; Tasaki, H | 1 |
| Gaskin, FS; Kamada, K; Korthuis, RJ; Yusof, M | 1 |
| Averill, DB; Chappell, MC; Ferrario, CM; Ganten, D; Trask, AJ | 1 |
| Boyd, R; Chapman, A; Ding, L; Wang, HD | 1 |
| Jin, L; Kern, MJ; Otey, CA; Somlyo, AV; Wamhoff, BR | 1 |
| Chen, S; Huang, H; Li, R; Liu, P; Tang, F; Wang, P; Zhang, H | 1 |
| Dong, N; Fa, X; Hou, J; Zhang, R | 1 |
| Gaikwad, AB; Ramarao, P; Viswanad, B | 1 |
| Dechend, R; Dietz, R; Fiebeler, A; Fischer, R; Gapelyuk, A; Gratze, P; Gruner, A; Gruner, K; Luft, FC; Muller, DN; Qadri, F; Schirdewan, A; Shagdarsuren, E; Wellner, M | 1 |
| Fujimoto, N; Matsumoto, T; Nishii, H; Nomura, M; Ozaki, Y | 1 |
| Elased, KM; Farah, V; Morris, M | 1 |
| Hay, M; Johnson, AK; Xue, B | 1 |
| Azuma, J; Dosaka, N; Iekushi, K; Katsuragi, N; Koibuchi, N; Morishita, R; Nagao, K; Ogihara, T; Sanada, F; Taniyama, Y | 1 |
| Mitsuyama, S | 1 |
| Hiroe, M; Imanaka-Yoshida, K; Inada, H; Nishioka, T; Onishi, K; Suzuki, M; Takakura, N; Yoshida, T | 1 |
| Han, J; Jung, ID; Kang, SH; Kim, N; Ko, JH; Park, WS; Park, YM; Son, YK; Warda, M | 1 |
| Fukumoto, H; Furubayashi, K; Ibaraki, T; Jin, D; Katsumata, T; Miyazaki, M; Muramatsu, M; Nishimoto, M; Takai, S | 1 |
| Comiter, CV; Copeland, D; Funk, J; Phull, H; Purves, T; Salkini, M | 1 |
| Boesen, EI; Pollock, DM | 1 |
| Anselmo-Franci, JA; Corezola, KL; Donadio, MV; Franci, CR; Kunrath, A; Lucion, AB; Sanvitto, GL | 1 |
| Feng, HY; Li, CM; Lu, XL; Qiu, SL; Su, QX; Zeng, Y; Zhang, C; Zhang, HL | 1 |
| Blanco-Colio, LM; Carvajal, G; Egido, J; Esteban, V; Plaza, JJ; Rodrigues-Díez, R; Rodríguez-Vita, J; Ruiz-Ortega, M; Rupérez, M; Sánchez-López, E | 1 |
| Anné, W; Beckers, F; Ector, H; Heidbüchel, H; Holemans, P; Lenaerts, I; Roskams, T; Willems, R | 1 |
| Alenina, N; Bader, M; da Costa Gonçalves, AC; Fraga-Silva, RA; Leite, R; Pinheiro, SV; Reis, AB; Reis, FM; Santos, RA; Touyz, RM; Webb, RC | 1 |
| Aebersold, R; Cooke, K; Flory, MR; Goodlett, DR; Hansen, S; Hohmann, L; Lee, H; Martin, D; Olson, JM; Paulovich, A; Piening, B; Prakash, A; Schwikowski, B; Shaffer, SA; Watts, J; Whiteaker, J; Zhang, H | 1 |
| Chappell, MC; Gallagher, PE; Groban, L; Pendergrass, KD; Pirro, NT; Yamaleyeva, LM | 1 |
| Adrogue, HJ; Huang, XR; Lan, HY; Soltero, L; Wang, W; Zhang, P | 1 |
| da Costa Goncalves, AC; Diedrich, A; Gollasch, M; Gross, V; Hercule, HC; Jordan, J; Luft, FC; Plehm, R; Tank, J; Wellner, M | 1 |
| Kopkan, L; Majid, DS | 1 |
| Hiramatsu, N; Hiromura, K; Ideura, H; Kaneko, Y; Kopp, JB; Kuroiwa, T; Maeshima, A; Nojima, Y; Sakairi, T; Shigehara, T; Takeuchi, S; Tomioka, M; Yamashita, S | 1 |
| Bagnoli, P; Cammalleri, M; Casini, G; Dal Monte, M; Martini, D | 1 |
| Chin-Dusting, J; Head, GA; Jackson, K; Jones, E; La Greca, L; Mayorov, DN; Morris, BJ | 1 |
| Borges, DR; Carvalho, LT; Kouyoumdjian, M; Nagaoka, MR; Nascimento, EA; Teixeira, FO | 1 |
| Boesen, EI; Hair, CD; Mintz, JD; Pollock, DM; Stepp, DW; Sullivan, JC | 1 |
| Kondo, T; Manabe, I; Matsubara, T; Murohara, T; Nagai, R; Numaguchi, Y; Sata, M; Tsuzuki, M; Yamada, T | 1 |
| Bader, M; Heilig, M; Lidström, J; Marquitz, M; Rimondini, R; Siems, WE; Sommer, WH | 1 |
| Ansar, S; Edvinsson, L; Nielsen, M; Vikman, P | 1 |
| Kobori, H; Nangaku, M; Navar, LG; Nishiyama, A | 1 |
| Gao, GD; Lin, YX; Liu, JJ; Xu, X; Zhou, J | 1 |
| Danchuk, S; Horvat, D; Puschett, JB; Sukhanov, S; Uddin, MN | 1 |
| Bak, S; Coleman, T; Osher, E; Semenkovich, CF; Stern, N; Tordjman, KM; Vechoropoulos, M; Yudovich, R | 1 |
| Hibi, T; Horikawa, H; Ishii, H; Kitamura, K; Kumagai, N; Kurita, S; Nakamoto, N; Saito, H; Tada, S; Toda, K; Tsunematsu, S | 1 |
| Hoshikawa, S; Ito, S; Mori, K; Nakagawa, Y; Ozaki, H; Tani, J; Yoshida, K | 1 |
| Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Ogawa, H; Shintaku, H; Tokutomi, Y; Yamamoto, E; Yamashita, T | 1 |
| Bautista, R; Franco, M; González, L; Martínez, F; Monreal, R; Pacheco, U; Pérez-Méndez, O; Sánchez-Lozada, LG; Santamaría, J; Tapia, E | 1 |
| Agha, R; Becker, RP; Chan, LS; Chen, L; Jin, T; Li, J; Marble, DJ; Peterson, JD | 1 |
| Dear, AE; Dousha, LF; Gaspari, TA; Liu, HB; Vinh, A; Widdop, RE | 1 |
| Bos, AP; Florquin, S; Haitsma, JJ; Lachmann, B; Lutter, R; Merkus, MP; van der Loos, CM; van Woensel, JB; Wösten-van Asperen, RM | 1 |
| Kikuta, K; Masamune, A; Satoh, K; Shimosegawa, T; Watanabe, T | 1 |
| Kolz, C; Potter, B; Reed, R; Rocic, P | 1 |
| Fukuda, D; Ishizaka, N; Nagai, R; Sata, M | 1 |
| Brooks, RM; Faraci, FM; Heistad, DD; Lund, DD | 1 |
| Brosnihan, KB; Ferrario, CM; Gallagher, PE; Joyner, J; Merrill, DC; Neves, LA; Stovall, K; Valdés, G | 1 |
| Bacurau, AV; Brum, PC; Casarini, DE; Coelho, MA; Evangelista, FS; Ferreira, JC; Krieger, JE; Oliveira, EM | 1 |
| Capone, C; Girouard, H; Iadecola, C; Lessard, A; Milner, TA | 1 |
| Graciano, ML; Jackson, K; Kobori, H; Navar, LG; Nishiyama, A; Ortiz, RM; Prieto-Carrasquero, MC; Seth, DM | 1 |
| Habibi, J; Hayden, MR; Karuparthi, PR; Lastra, G; Manrique, C; Sowers, JR; Stas, S; Wasekar, C | 1 |
| Anderson, S; Komers, R; Lindsley, JN; Oyama, TT; Schutzer, W; Xue, H | 1 |
| Abdulhag, UN; Helmchen, U; Hilgers, KF; Kirchhoff, F; Krebs, C; Maas, R; Meyer-Schwesinger, C; Stahl, RA; Wenzel, U; Wolf, G | 1 |
| Liu, AJ; Liu, JG; Shen, FM; Su, DF; Yi-Ming, W; Zhang, W | 1 |
| Figtree, G; Rasmussen, HH | 1 |
| Cassis, LA; Daugherty, A; King, VL | 1 |
| Cornish, KG; Liu, D; Mousa, TM; Zucker, IH | 1 |
| Deng, W; Yin, YH; Zhang, A | 1 |
| Taylor, WR; Velasquez-Castano, JC | 1 |
| Middlekauff, HR; Negrão, CE | 1 |
| Dart, AM; Du, XJ; Gao, XM; Gibbs, ME; Kiriazis, H; Lambert, G; Ming, Z; Moore, XL; Su, Y; Wang, K; Xu, Q | 1 |
| Akino, M; Matsui, Y; Okamoto, H; Onozuka, H; Tsutsui, H; Xu, Z | 1 |
| Alexanderson, C; Andersson, IJ; Bergström, G; Holmäng, A; Johansson, ME; Skøtt, O | 1 |
| Cassaglia, PA; Griffiths, RI; Walker, AM | 1 |
| Felder, RB; Gomez-Sanchez, E; Wei, SG; Weiss, RM; Yu, Y; Zhang, ZH | 1 |
| Cao, G; Mastai, R; Mella, J; Muñoz, MC; Pereyra, L; Toblli, JE | 1 |
| Egawa, T; Hanafusa, N; Kawasaki, H; Mio, M; Takatori, S; Yabumae, N; Zamami, Y | 1 |
| Fink, GD; King, AJ; Novotny, M; Swain, GM | 1 |
| Berndt, MC; Fahmy, RG; Kavurma, MM; Khachigian, LM; Luo, X; Midgley, VC; Molloy, MP; Peden, R; Santiago, FS; Tan, NY | 1 |
| Baud, L; Bellocq, A; de Castro Keller, A; Haymann, JP; Letavernier, E; Mesnard, L; Perez, J | 1 |
| Llinas, MT; Loria, A; Reverte, V; Saez, F; Salazar, F; Salazar, FJ | 1 |
| Badimon, L; Costales, P; Huesca-Gómez, C; Llorente-Cortés, V; Sendra, J | 1 |
| Backx, PH; Crackower, MA; Dawood, F; Kassiri, Z; Liu, PP; Liu, QC; Oudit, GY; Penninger, JM; Scholey, JW; Zhou, J | 1 |
| Chai, SY; Gaspari, TA; Vinh, A; Widdop, RE | 1 |
| Nagami, GT | 1 |
| Chen, WP; Chiang, FT; Hsu, KL; Hwang, JJ; Lai, LP; Lin, JL; Tsai, CT; Tseng, CD; Tseng, YZ | 1 |
| Boomsma, F; de Beer, VJ; Dekkers, DH; Duncker, DJ; Lamers, JM; Merkus, D; Pijnappels, DA; Sorop, O | 1 |
| Bíbová, J; Hampl, V; Herget, J; Jakoubek, V | 1 |
| Bucala, R; Horiuchi, M; Iwai, M; Kaneko, S; Matsushima, K; Sakai, N; Wada, T | 1 |
| Chiţac, D; Radulian, G; Simion, E; Stoian, M; Stoica, V | 1 |
| Brosnihan, KB; Ferrario, CM; Figueroa, JP; Ganten, D; Li, P | 1 |
| Jin, D; Kimura, M; Kirimura, K; Miyazaki, M; Sakonjo, H; Takai, S; Tanaka, K | 1 |
| Akasaka, H; Kaneda, Y; Katsuya, T; Kikuchi, Y; Morishita, R; Nakagami, H; Ogihara, T; Rakugi, H; Saitoh, S; Shimamoto, K | 1 |
| Beretz, A; Etienne-Selloum, N; Kane, MO; Sarr, M; Schini-Kerth, VB; Walter, A | 1 |
| Benzoni, D; Issiakhem, M; Liu, KL | 1 |
| Chappell, MC; Ferrario, CM; Jessup, JA; Trask, AJ | 1 |
| Ferreira, AJ; Raizada, MK | 1 |
| Chen, CM; Chou, HC; Lu, KS; Wang, LF | 1 |
| Carlström, M; Eriksson, UJ; Lai, EY; Ma, Z; Patzak, A; Persson, AE; Sendeski, M; Steege, A; Zabihi, S | 1 |
| Anan, A; Irie, M; Iwata, K; Sakisaka, S; Shakado, S; Sohda, T; Takeyama, Y | 1 |
| Quigley, R | 1 |
| Deng, BP; Dong, B; Dong, QL; Feng, JB; Li, SY; Liu, B; Liu, CX; Pan, CM; Song, HD; Yang, YP; Yu, QT; Zhang, C; Zhang, MX; Zhang, Y; Zhao, YX; Zhu, L | 1 |
| Kang, JJ; Meer, EJ; Peti-Peterdi, J; Sipos, A; Toma, I; Vargas, SL | 1 |
| Anand-Srivastava, MB; Li, Y; Saha, S | 1 |
| Cai, YM; Gu, HB; Hao, YH; He, JG; Hu, XS; Liao, XX; Ma, H; Tian, F; Wang, LJ; Zhang, WW; Zhou, QL; Zou, HM | 1 |
| Hashimoto, T; Ichiki, T; Imayama, I; Inanaga, K; Miyazaki, R; Sadoshima, J; Sunagawa, K | 1 |
| Ueda, S | 1 |
| O'Rourke, ST; Sumners, C; Sun, C; Yao, F | 1 |
| Botros, FT; Casarini, DE; Kobori, H; Navar, LG; Pagan, J; Prieto-Carrasquero, MC; Seth, DM | 1 |
| Hou, Y; Matsuo, O; Okada, K; Okamoto, C; Ueshima, S | 1 |
| Hirata, Y; Kimura, K; Nagai, R; Nagano, T; Nishimatsu, H; Oba, S; Suzuki, E; Takahashi, M; Takeda, R | 1 |
| Hu, X; Shi, Y; Wei, EQ; Xu, M; Zhang, JF; Zhang, YM | 1 |
| Cassis, LA; Daugherty, A; Henriques, T; Yiannikouris, FB; Zhang, X | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Pendergrass, KD; Pirro, NT; Westwood, BM | 1 |
| Barbacid, M; Bustelo, XR; Cañamero, M; Guerra, C; Sauzeau, V; Schuhmacher, AJ | 1 |
| Clark, SE; Ferrario, CM; Ibdah, JA; Morris, EM; Sowers, JR; Thyfault, JP; Uptergrove, GM; Wei, Y; Whaley-Connell, AT | 1 |
| Felder, RB; Kang, YM; Weiss, RM; Xue, B; Zhang, ZH | 1 |
| Burchette, JL; Coffman, TM; Crowley, SD; Frey, CW; Gould, SK; Griffiths, R; Howell, DN; Kim, HS; Makhanova, N; Ruiz, P; Tharaux, PL; Yan, M | 1 |
| Barauna, VG; Krieger, JE; Magalhaes, FC; Oliveira, EM | 1 |
| Choi, HC; Kang, YJ; Kim, HS; Kim, HY; Song, IH | 1 |
| Ferrario, CM; Igase, M; Kohara, K; Miki, T; Nagai, T | 1 |
| Khalil, RA; Koledova, VV; Qiao, X; Raffetto, JD | 1 |
| Cushman, DW; Ondetti, MA | 1 |
| Hollenberg, NK; Williams, GH | 1 |
| Agnati, L; Fuxe, K; Ganten, D; Hökfelt, T; Rascher, W; Unger, T | 1 |
| Huang, WC; Navar, LG; Ploth, DW | 1 |
| Campbell, WG; Donohue, JA; Duket, LH | 1 |
| Loyke, HF | 1 |
| Braley, LM; Menachery, A; Williams, GH | 1 |
| Zimmerman, BG | 1 |
| Bing, RF; Kumar, A; Swales, JD; Thurston, H | 1 |
| Shibata, K | 1 |
| Gaida, M; Greenberg, S; McGowan, C | 1 |
| Bing, RF; Marks, ES; Swales, JD; Thurston, H | 1 |
| Becker-McKenna, B; Bidani, A; Churchill, PC; Fleischmann, L | 1 |
| Croxatto, HR; Roblero, JS; Vío, CP | 1 |
| Brody, MJ; Haywood, JR; Touw, KB | 1 |
| Iwamoto, HS; Rudolph, AM | 1 |
| Fowler, WL; Johnson, JA; Kurz, KD; Payne, CG; Siripaisarnpipat, S | 1 |
| Edvinsson, L; Hardebo, JE; Larsson, B; Owman, C; Skärby, T | 1 |
| Crofton, JT; Lee-Kwon, WJ; Shade, RE; Share, L | 1 |
| Marshall, RJ; Muir, AW; Winslow, E | 1 |
| Bryan, WJ; Fink, GD | 1 |
| Criscione, L; Dohi, Y; Lüscher, TF; Pfeiffer, K | 1 |
| Haudenschild, CC; Jacobs, AK; Landau, C | 1 |
| Brooks, DP; Contino, LC; Edwards, RM; Gowan, C; Short, BG; Trizna, W | 1 |
| Kunihara, M; Kushida, H; Morita, O | 1 |
| Anania, V; Demontis, MP; Fattaccio, MC; Glorioso, N; Madeddu, P; Palomba, D; Parpaglia, PP; Pollock, D; Varoni, MV | 1 |
| Adamiak, D; Kregel, KC; Mott, A; Redlich, T; Stauss, HM; Unger, T; Zhu, YC | 1 |
| Aubert, JF; Brunner, HR; Niederberger, M; Nussberger, J; Waeber, B | 1 |
| Mineshita, S; Miyazaki, M; Sanaka, M; Shimakura, K; Wang, L | 1 |
| Abraham, G; Cserep, G; Simon, G | 1 |
| Lorell, BH | 1 |
| Okamura, T; Toda, N; Yoshida, K | 1 |
| Büch, M; Gerstberger, R; Paul, M; Rettig, R; Schnatterbeck, P | 1 |
| Jackson, AA; Langley-Evans, SC | 1 |
| Rucinska, EJ; Sweet, CS | 1 |
| Fukai, C; Furuta, K; Hase, K; Kosakai, K; Mochizuki, S; Ohkura, Y; Sato, T; Tomiyama, A; Wakabayashi, S | 1 |
| Ichikawa, M; Kumagai, H; Kumagai, K; Nishizawa, M; Ryuzaki, M; Saruta, T; Suzuki, H | 1 |
| Georgiev, VP; Kambourova, TS; Lazarova, MB | 1 |
| Inada, Y; Ishimura, Y; Kanagawa, R; Nishikawa, K; Wada, T | 1 |
| Fujishima, K; Hachisu, M; Hui, C; Katano, K; Kawano, K; Konno, F; Nagura, J; Ogino, H; Yamamoto, M; Yasuda, S | 1 |
| al-Barazanji, KA; Balment, RJ | 1 |
| Hase, NK; Murthy, KR | 1 |
| Hughes, AD; Ibrahim, J; Schachter, M; Sever, PS | 1 |
| Matsumori, A; Sasayama, S; Tanaka, A; Wang, W | 1 |
| Hanss, BG; Lewy, JE; Vari, RC | 1 |
| Botarelli, M; Corsico, N; Martelli, EA; Mattera, GG; Tobia, P; Vesci, L | 1 |
| Alhenc-Gelas, F; Arnal, JF; Challah, M; Corvol, P; Huang, H; Llorens-Cortes, C; Michel, JB | 1 |
| Pouleur, H | 1 |
| Ross, M | 1 |
| Berdeaux, A; Ghaleh, B; Giudicelli, JF; Richard, V | 1 |
| Diamant, D; Dzau, VJ; Ingelfinger, JR; Litwin, SE; Riegger, G; Schunkert, H; Tang, SS | 1 |
| Fujishima, M; Hirakata, H; Kanai, H; Kiyama, S; Okuda, S; Tomooka, S | 1 |
| Imura, Y; Kawamura, M; Nakao, M; Nishikawa, K; Okuda, H; Shino, A; Terashita, Z | 1 |
| Bader, M; Ganten, D; Hackenthal, E; Mullins, JJ; Münter, K; Peters, J | 1 |
| Guignard, JP; Huet, F; John, E; Semama, D | 1 |
| Higaki, J; Kaneda, Y; Mikami, H; Morishita, R; Ogihara, T; Tomita, N; Yu, H | 1 |
| Brune, ME; Buckner, SB; De, B; DeBernardis, JF; Kerkman, DJ; Lee, JY; Opgenorth, TJ; Warner, RB; Winn, M; Zydowsky, TM | 1 |
| Baudouin, SV; Evans, TW | 1 |
| Porter, JP; Toney, GM | 1 |
| Ichikawa, M; Jimbo, M; Kumagai, H; Matsumura, Y; Ryuzaki, M; Saruta, T; Suzuki, H | 1 |
| Elghozi, JL; Ponchon, P | 1 |
| Delbridge, LM; Harris, PJ; Morgan, TO | 1 |
| Acker, WR; Chang, RS; Drag, MD; Fujita, T; Greenlee, WJ; Holder, DJ; Huckle, WR; Johnson, RG; Kim, D; Mantlo, NB; McFall, RC; Ondeyka, DL; Powers, M; Reilly, CF; Schwartz, RS; Stabilito, II | 1 |
| Kass, DA; Recchia, FA; Saeki, A; Tunin, RS | 1 |
| Greene, EL; Hostetter, TH; Kren, S | 1 |
| Basinger, MA; Deegan, PM; Hande, KR; Jones, MM; Nolan, C; Ryan, MP | 1 |
| Esquerro, E; López-Novoa, JM; Rivas-Cabãnero, L | 1 |
| Hasegawa, S; Imai, S; Kanda, T; Kobayashi, I; Nagai, R; Nakano, M; Suzuki, T; Taniguchi, Y | 1 |
| Dumont, EC; Lambert, C; Lamontagne, D | 1 |
| Bizollon, CA; Gharib, C; Lantelme, P; Lo, M; Mullins, JJ; Sassard, J | 1 |
| Epstein, M; Forster, HG; Hohman, TC; ter Wee, PM | 1 |
| Fukamizu, A; Horiguchi, H; Ishida, J; Murakami, K; Sugiyama, F; Takimoto, E | 1 |
| Dusting, GJ; Hickey, H; Hyland, R; Makdissi, M; Wilks, D | 1 |
| Gura, T | 1 |
| Nasa, Y; Okumura, Y; Sanbe, A; Takeo, S; Toga, W | 1 |
| Blantz, RC; De Nicola, L; Gabbai, FB; Keiser, JA; Obagi, S; Peterson, OW; Thomson, SC; Tucker, BJ; Wilson, CB | 1 |
| Bohlender, J; Ganten, D; Ganten, U; Gross, V; Lippoldt, A; Luft, FC | 1 |
| Mohamed, EI; Remuzzi, A | 1 |
| Charlier, AA; Donckier, J; Hayashida, W; Pouleur, H; Van Mechelen, H | 1 |
| Cohen, A; Erlich, Y; Rosenmann, E; Rosenthal, T | 1 |
| Katori, M; Majima, M | 1 |
| Anderson, S; Kennefick, TM | 1 |
| Wolf, G; Ziyadeh, FN | 1 |
| Border, WA; Noble, NA | 2 |
| Böhm, M; Ettelbrück, S; Flesch, M; Knorr, A; Pinto, Y; Schiffer, F; Stasch, JP; Zolk, O | 1 |
| Miura, T; Nakano, A; Shimamoto, K; Suzuki, K; Ura, N | 1 |
| Albrecht, D; Ganten, D; Henklein, P | 1 |
| Hostetter, TH; Junaid, A; Rosenberg, ME | 1 |
| Allen-Mersh, TG; Carnochan, P; Dworkin, MJ | 1 |
| Bai, SA; Christ, DD; Hellyer, P; Lankford, SM; Plummer, D | 1 |
| Amano, H; Hashimoto, K; Hirata, T; Inokuma, K; Mikoshiba, I; Okuhira, M; Tamura, K | 1 |
| Herizi, A; Jover, B; Mimran, A | 1 |
| Anarat, A; Anarat, R; Duman, N; Kibar, M; Noyan, A | 1 |
| Ford, WR; Jugdutt, BI; Khan, MI | 1 |
| Kimura, M; Nakashima, M; Ohashi, K; Umemura, K | 1 |
| Cameron, EM; Fink, MP; Sellke, FW; Wang, SY | 1 |
| Angulo, J; López-Novoa, JM; Marín, J; Peiró, C; Regadera, J; Rodríguez-López, AM; Sánchez-Ferrer, CF | 1 |
| Charlier, AA; Donckier, JE; Heyndrickx, GR; Hodeige, DG; Ketelslegers, JM; Massart, PE; Van Mechelen, H | 1 |
| Braam, B; Koomans, HA; Turkstra, E | 1 |
| Chappell, MC; Dean, RH; Ferrario, CM; Iyer, SN | 1 |
| Brock, JW; Ichikawa, I; Miyazaki, Y; Nishimura, H; Tsuchida, S; Yerkes, E | 1 |
| Ogilvie, RI; Zborowska-Sluis, D | 1 |
| Akasu, M; Arakawa, K; Ideishi, M; Kinoshita, A; Sasaguri, M; Urata, H | 1 |
| du Cailar, G; Herizi, A; Jover, B; Mimran, A; Pasquié, JL | 1 |
| Au-Fliegner, M; Gosche, JR; Salami, S | 1 |
| Okumura, K; Ra, C; Ravetch, JV; Shirato, I; Suzuki, Y; Takai, T; Tomino, Y | 1 |
| Greene, AS | 1 |
| Greenland, BD; Grossman, W; Lynch, JJ; Shen, YT; Wiedmann, RT | 1 |
| Bauters, C; Bertrand, ME; Van Belle, E | 1 |
| Engler, S; Paul, M; Pinto, YM | 1 |
| Makimoto, K; Yamamoto, H | 1 |
| Bastien, N; Lambert, C | 1 |
| Moreau, P | 1 |
| Clair, MJ; de Gasparo, M; Hebbar, L; Hendrick, JW; Houck, WV; Kribbs, SB; Krombach, RS; Mukherjee, R; Rios, G; Spinale, FG; Whitebread, S | 1 |
| de Gasparo, M; Iannini, JP; Melton, DM; Mukherjee, R; Spinale, FG | 1 |
| Kawachi, H; Kimura, H; Nakamura, T; Obata, J; Ohno, S; Shimizu, F; Yoshida, Y | 1 |
| Brenner, BM; Dietz, R; Höhnel, K; Mackenzie, HS; Pagel, I; Scheuermann, M; Willenbrock, R | 1 |
| Herizi, A; Jover, B; Mimran, A; Pasquié, JL | 1 |
| Fierro, G; Ram, S; Venkata, C | 1 |
| Khirmanov, VN; Moiseeva, OM; Pinaev, GP; Polevaia, EV; Selivanova, GV; Semenova, EG; Vlasova, TD | 1 |
| Crespo, MJ | 1 |
| Chen, S; Hu, T; Li, G; Lu, E | 1 |
| Fogo, A; Ichikawa, I; Miyazaki, Y; Tsuchida, S | 1 |
| Oğütman, C; Ozdem, SS | 1 |
| Gard, PR; Mandy, A; Sutcliffe, MA | 1 |
| Goldsmith, SR | 1 |
| Baba, K; Fujita, T; Ikeda, J; Jin, D; Kirimura, K; Miyazaki, M; Sakaguchi, M; Takai, S | 1 |
| Meyers, CM | 1 |
| Brooks, DP; Ohlstein, EH; Ruffolo, RR | 1 |
| Gould, RJ; Grossman, W; Kusma, SE; Lynch, JJ; Painter, CA; Stump, GL; Thomas, JM; Wallace, AA | 1 |
| Abe, S; Fujiwara, H; Nakamura, M; Tanaka, M | 1 |
| Attias, J; Aviram, M; Coleman, R; Heinrich, R; Keidar, S | 1 |
| Barbe, F; Campbell, DJ; Crozatier, B; Hittinger, L; Su, JB | 1 |
| Açikgöz, B; Akpinar, G; Bingöl, N; Usseli, I | 1 |
| Ito, M; Koyama, H; Maeda, T; Ohshige, A; Okamura, H; Yoshimura, T | 1 |
| Basu, MK; Das, N; Raay, B | 1 |
| Browne, AE; Chatterjee, K; Chou, TM; Lee, RJ; Parmley, WW; Pulukurthy, S; Sievers, RE; Sudhir, K; Sun, Y; Zhu, B | 1 |
| Aizawa, T; Ingelfinger, JR; Ishizaka, N; Mori, I; Nagai, R; Ohno, M; Taguchi, Ji; Tang, SS | 1 |
| Edgington, TS | 1 |
| Croatt, AJ; Haugen, EN; Nath, KA | 1 |
| Kelleher, DK; Thews, O; Vaupel, P | 1 |
| Jones, EA; Shahed, A; Shoskes, DA | 1 |
| Lake-Bruse, KD; Sigmund, CD | 1 |
| Friberg, P; Johansson, M | 1 |
| Adams, MA; Friberg, P; Isgaard, J; Wåhlander, A; Wickman, A | 1 |
| Bandinelli, B; Bertolozzi, I; Boddi, M; Cecioni, I; Galanti, G; Liguori, P; Modesti, PA; Paniccia, R; Perna, A; Polidori, G; Serneri, GG; Vanni, S | 1 |
| Howard, EF; Landon, EJ; Myers, PR; Steimle, A; Takagi, T; Tamura, M; Tanner, M | 1 |
| Fleming, S | 1 |
| Bieringer, M; Dechend, R; Fiebeler, A; Ganten, D; Haller, H; Lindschau, C; Luft, FC; Mervaala, EM; Müller, DN; Park, JK; Schäfer, O; Schmidt, F; Schneider, W | 1 |
| Cooper, ME; Gilbert, RE; Huang, XR; Johnson, RJ; Lai, KN; Lan, HY; Wu, LL; Yang, N; Yu, XQ | 1 |
| Ji, H; Sandberg, K | 1 |
| Espiner, EA; Frampton, CM; Nicholls, MG; Powell, JD; Rademaker, MT; Richards, AM; Troughton, RW; Yandle, TG | 1 |
| Meyer, TW; Olson, JL; Sorooshian, M | 1 |
| Arakawa, K; Urata, H | 1 |
| Anderson, WP; Denton, KM; Edgley, AJ; Fitzgerald, SM; Kett, MM; Stevenson, KM | 1 |
| Anderson, WP; Bergström, G; Edgley, AJ; Kett, MM; Stevenson, KM; Worthy, K | 1 |
| Campese, VM; Gamburd, M; Mozayeni, P; Ye, S; Zhong, H | 1 |
| Iwao, H; Izumi, Y; Kim, S; Yano, M; Yasumoto, H; Zhan, Y | 1 |
| Artuso, A; Bouriquet, N; Casellas, D; Moore, LC; Walcott, B | 1 |
| Sandmann, S; Unger, T; Yu, M | 1 |
| Abraham, JA; Damm, D; Garrard, LJ; Henson, M; Joly, AH; Lam, A; Schreiner, GF; Stanton, LW; White, T | 1 |
| Chen, YF; Dell'Italia, LJ; Lucchesi, P; Mori, T; Oparil, S; Perry, GJ; Wei, CC; Xu, XY | 1 |
| Hong, KW; Kim, CD; Kim, HH; Kim, S; Kim, YK; Kwak, YK; Yoo, S | 1 |
| Rong, P; Skinner, SL; Wilkinson-Berka, JL | 1 |
| Berry, C; Brosnan, MJ; Dominiczak, AF; Fennell, J; Hamilton, CA | 1 |
| Francis, SC; Gelband, CH; Huentelman, MJ; Katovich, MJ; Pachori, AS; Raizada, MK | 1 |
| Alvarez, AL; Finkielman, S; García, SI; Garfunkel, VM; Pirola, CJ; Porto, PI | 1 |
| Cheng, ZJ; Fiebeler, A; Ganten, D; Ganten, U; Lapatto, R; Luft, FC; Mervaala, EM; Müller, DN; Nurminen, K; Tikkanen, I; Vapaatalo, H | 1 |
| Luft, FC | 1 |
| Cheng, CP; Cheng, HJ; Igawa, A; Little, WC; Ohte, N; Onishi, K; Suzuki, M; Tachibana, H; Ukai, T; Zhang, ZS | 1 |
| Kulkarni, SK; Raghavendra, V | 1 |
| Opie, LH; Sack, MN | 1 |
| Cooper, ME; de Gasparo, M; Webb, RL | 1 |
| Harrison-Bernard, LM; Kobori, H; Navar, LG | 1 |
| Derebail, VK; Pollock, DM; Pollock, JS; Yamamoto, T | 1 |
| Andrzejak, R; Skoczyńska, A; Wróbel, J | 1 |
| Chávez, M; Egido, J; Gómez-Garre, D; Gordon, K; Herrera-Acosta, J; Johnson, RJ; Largo, R; Parra, G; Pons, H; Quiroz, Y; Rincón, J; Rodríguez-Iturbe, B | 1 |
| Aikawa, M; Hill, CC; Lee, RT; Libby, P; Sakamoto, H; Taylor, WR; Weiss, D | 1 |
| Burnett , JC; Grande, JP; Hart, CY; Housmans, PR; Meyer, DM; Redfield, MM; Tazelaar, HD | 1 |
| Brooker, G; Fleming, S; Kantachuvesiri, S; Kotelevtsev, Y; Lammie, AG; McGrath, I; Mullins, JJ; Peters, B; Peters, J | 1 |
| Gaffney, FA; Ichihara, S; Ichiki, T; Inagami, T; Price, E; Senbonmatsu, T | 1 |
| Ambrosio, G; Levy, BI; Pries, AR; Struijker-Boudier, HA | 1 |
| Adam, A; Gagnon, C; Gosselin, H; Kapuku, G; Lambert, C; Meloche, S; Pelletier, S; Rouleau, JL | 1 |
| Bosch, RJ; Egido, J; Esbrit, P; Fernández-Agulló, T; Gazapo, R; Largo, R; Ortega, A; Santos, S | 1 |
| Guidi, E; Hollenberg, NK | 1 |
| Hanley, FL; He, YP; Malhotra, SP; Reddy, VM; Riemer, RK; Thelitz, S | 1 |
| Dobrian, AD; Prewitt, RL; Schriver, SD | 1 |
| Garvin, JL; Ortiz, PA | 1 |
| Aubert, JF; Brunner, H; Morgan, T | 1 |
| Newaz, MA; Oyekan, AO | 1 |
| Chao, CR; El-Haddad, H; El-Haddad, MA; Ross, MG; Sayed, AA | 1 |
| Buikema, H; Ganten, D; Hoffmann, S; Inagami, T; Krause, T; Lindschau, C; Pagel, I; Paul, M; Pinto, YM; Urata, H; van Geel, PP; van Gilst, WH; Willenbrock, R | 1 |
| Border, WA; Gaedeke, J; Noble, NA; Peters, H | 1 |
| Meyer, TW; Toke, A | 1 |
| Liang, X; Su, M; Xie, X; Yu, G; Zhao, S | 1 |
| Asakura, M; Asanuma, H; Beppu, S; Higashiyama, S; Hori, M; Ishiguro, H; Ishikura, F; Kitakaze, M; Liao, Y; Matsumura, Y; Node, K; Ohmoto, H; Sanada, S; Tada, M; Takashima, S; Takeda, H; Yoshinaka, T; Yoshino, K | 1 |
| Bishop, SP; Dell'Italia, LJ; Dillon, AR; Hankes, GH; Ideker, R; Powell, P; Rynders, P; Schultz, D; Spinale, FG; Su, X; Walcott, G; Wei, CC | 1 |
| Liu, Y; Wang, M; Xu, D | 1 |
| Dixon, D; Hercule, HC; Oyekan, AO; Pamugo, J | 1 |
| Brosnan, MJ; Dominiczak, AF; Graham, D; Hamilton, CA; Jardine, E; Lygate, CA | 1 |
| Ferrario, CM | 1 |
| Bofilis, E; Iliodromitis, EK; Karavolias, GK; Kremastinos, DT; Tasouli, A; Vlahakos, DV | 1 |
| Browne, AE; Chatterjee, K; Lee, RJ; Parmley, WW; Sievers, RE; Sun, Y; Zhu, B | 1 |
| Adler, GK; Martinez, DV; Matsumura, M; Ochoa-Maya, M; Oestreicher, E; Rocha, R; Roubsanthisuk, W; Williams, GH | 1 |
| Capdevila, JH; Hammock, BD; Imig, JD; Morisseau, C; Zhao, X | 1 |
| Benter, IF; Estes, A; Gaber, L; Karzoun, NA; Khandekar, Z; Ljuca, F; Malik, KU; Muthalif, MM; Uddin, MR | 1 |
| August, M; Bodenschatz, M; Förstermann, U; Griendling, K; Kleschyov, AL; Lassègue, B; Li, H; Meinertz, T; Mollnau, H; Münzel, T; Oelze, M; Schulz, E; Szöcs, K; Tsilimingas, N; Walter, U; Wendt, M | 1 |
| Asakawa, M; Hasegawa, H; Kadowaki, T; Komuro, I; Kubota, N; Masuda, Y; Nagai, T; Saito, T; Takano, H; Uozumi, H | 1 |
| Dell'Italia, LJ; Dillon, SR; Hankes, GH; Mukherjee, R; Perry, GJ; Rynders, P; Spinale, FG; Wei, CC | 1 |
| Assem, M; Bernard, C; Ecarnot-Laubriet, A; Lecour, S; Moisant, M; Poirson-Bichat, F; Rochette, L; Solary, E; Teyssier, JR | 1 |
| Belloni, AS; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rossi, GP; Sartore, S | 1 |
| Durie, M; Levy, BI; Silvestre, JS; Tamarat, R | 1 |
| Aoki, M; Hashiya, N; Hiraoka, K; Kaneda, Y; Matsumoto, K; Morishita, R; Nakamura, T; Ogihara, T; Taniyama, Y; Yamasaki, K | 1 |
| Eliahou, H; Iaina, A; Solomon, S | 1 |
| Heros, RC; Negoro, M; Zervas, NT | 1 |
| Corvol, P; Lagneau, P; Ménard, J; Plouin, PF | 1 |
| Besch, HR; Elharrar, V; Molello, J; Watanabe, AM; Zipes, DP | 1 |
| Nemeroff, CB; Prange, AJ | 1 |
| Cole, FE; Frolich, ED; MacPhee, AA | 1 |
| Casals-Stenzel, J; Lever, AF; Millar, JA; Morton, JJ; Riegger, AJ; Tree, M | 1 |
| Davis, JO; DeForrest, JM; Freeman, RH; Rowe, BP; Seymour, AA; Williams, GM | 1 |
| Baer, L; Brunner, HR; Bühler, FR; Gavras, H; Laragh, JH; Sealey, JE; Vaughan, ED | 1 |
| Harper, AM; Jones, JV; MacKenzie, ET; Strandgaard, S | 1 |
| Clunie, GJ | 1 |
| Davis, JO | 1 |
| Ober, WB | 1 |
| Zervas, NT | 1 |
| Reiner, NE; Thompson, WL | 1 |
| Dienemann, H; Helmchen, U; Kirchertz, EJ; Kneissler, U; Stahl, R | 1 |
| Melman, A | 1 |
| Arendell, R; Dean, RH; Hollifield, JW; Lawson, JD; Meacham, PW; Petracek, MR | 1 |
| Gepts, W; Lambert, PP; Potvliege, PR; Sadowski, J; Staroukine, M | 1 |
| Liard, JF | 1 |
| Artiukhina, NI; Gekht, KK; Kuvaeva, OF; Levshina, IP | 1 |
| Adams, DF; Hollenberg, NK | 1 |
| Ayers, CR; Carey, RM; Katholi, RE; Kimbrough, HM; Morton, CL; Vaughan, ED; Yancey, MR | 1 |
| Davis, JO; Morris, BJ; Williams, GM; Zatzman, ML | 1 |
| Feldhaus, RA; Isakson, PC; McKnight, RC; Needleman, P; Raz, A; Shofer, F | 1 |
| Morrison, A; Needleman, P; Nishikawa, K | 1 |
| Davis, JO; Freeman, RH; Lohmeier, TE; Watkins, BE | 1 |
| D'Agostini, RJ; Freedman, MT; Heptinstall, RH; Scott, WW; Siegelman, SS; Solez, K; Stawowy, L | 1 |
| Eliahou, HE; Gavendo, S; Iaina, A; Solomon, S | 1 |
| Dimitrov, T; Kiprov, D; Orbetzova, V | 1 |
| Kolloch, RE; Overlack, A; Stumpe, KO | 1 |
| Hashida, J; Kajiwara, N; Kita, T; Kobayashi, Y; Uchiyama, T | 1 |
| Becker, CH; Engler, E; Herrmann, HJ; Matthias, D; Wachtel, W; Wolf, I | 1 |
| Bumpus, FM; Helmchen, U; Khairallah, PA; Khosla, MC; Sen, S | 1 |
| Armstrong, FB; Brooks, B; Brown, P; Byers, LW; Germain, GS; Leach, BE; Muirhead, EE; Pitcock, JA | 1 |
| Farrar, JK; Graham, DI; Jones, JV; MacKenzie, ET; Strandgaard, S | 1 |
| Laragh, JH; Vaughan, EF | 1 |
| Romero, JC; Strong, CG; Torres, VE; Wilson, DM | 1 |
| Brunner, HR; Gavras, H; Laragh, JH; Thurston, H | 1 |
| Braverman, B; Davis, JO; Johnson, JA | 1 |
| Michailov, ML | 1 |
| Becker, CH; Engler, E; Hecht, K; Herrmann, HJ; Kreher, C; Matthias, D | 1 |
| Anderson, WJ; Manlove, A; Michelakis, AM; Oates, JA; Van Way, CW | 1 |
| Dach, JL; Kurtzman, NA | 1 |
| Ambrosioni, E; Bacchelli, S; Borghi, C; Degli Esposti, D | 1 |
| Kishi, K | 1 |
| Yamashita, T | 1 |
| Armstrong, PW; Forster, C; Larosa, G | 1 |
| Brilla, CG; Weber, KT | 1 |
| Firth, JD; Gove, CD; Panos, MZ; Raine, AE; Williams, R | 1 |
| Katzeff, IE; Norton, GR; Rosendorff, C; Woodiwiss, AJ | 1 |
| Bottari, SP; Obermüller, N; Qadri, F; Steckelings, UM; Unger, T; Veltmar, A | 1 |
| Ando, Y; Kusano, E | 1 |
| Panek, RL; Ryan, MJ; Taylor, DG; Weishaar, RE | 1 |
| Brilla, CG; Campbell, SE; Janicki, JS; Reddy, HK; Weber, KT | 1 |
| Riegger, AJ | 1 |
| Daugherty, S; Fonken, SJ; Goldman, S; Lee, RW; Morkin, E; Raya, TE; Timmermans, PB; Wong, PC | 1 |
| Bolton, WK; Brand-Elnaggar, J; Sadovnic, MJ | 1 |
| Blaine, EH; Koepke, JP; Smits, GJ | 1 |
| Campbell, KA; Li, SS; Sitzmann, JV; Wu, YP | 1 |
| Fukuchi, S; Mizuno, K; Niimura, S; Tani, M | 1 |
| Gromov, LA; Sereda, PI | 1 |
| Arnolda, L; Johnston, CI; McGrath, BP | 1 |
| Ganten, D; Mullins, JJ; Peters, J | 1 |
| Dunn, MJ | 1 |
| Sweet, CS | 1 |
| Brecher, P; Chobanian, AV; Sarzani, R; Takasaki, I | 1 |
| Inukai, T; Nakao, K; Yamamoto, S | 1 |
| Ladenson, PW; Lynch, DR; Wilson, SK | 1 |
| Boucek, MM; Chang, R; Synhorst, DP | 1 |
| Daniel, SS; James, S; Stark, RI; Tropper, PJ | 1 |
| Blantz, RC; Gabbai, FB; Wilson, CB | 1 |
| Heagerty, AM; Ollerenshaw, JD; Swales, JD; West, KP | 1 |
| Fejes-Tóth, G; Filep, J | 1 |
| Brosnihan, KB; Ferrario, CM; Saruta, T; Suzuki, H | 1 |
| Chevalier, RL; Peach, MJ | 1 |
| Guidi, E | 1 |
| Bailey, RW; Bulkley, GB; Oshima, A | 1 |
| Olson, NC | 1 |
| Dzau, VJ; Gibbons, GH; Nabel, EG | 1 |
| Gross, PM; Kadekaro, M | 1 |
| Branch, RA; Gerkens, JF; Heidemann, HT; Jackson, EK; Workman, RJ | 1 |
| Bacher, S; Beck, A; Grasmugg, B; Raberger, G; Singer, E | 1 |
| Di Pette, D; Watson, AJ | 1 |
| Ljunggvist, A; Ungerstedt, U | 1 |
| Gnüchtel, U; Nitschkoff, S; Wallrabe, D | 1 |
| Hoobler, SW; Lazar, JD; Romero, JC | 1 |
| Border, JR; Heyden, WC; Hopkinson, BR; Jacobs, RR; Schenk, WG | 1 |
| Boyd, GW; Louis, WJ; Macdonald, GJ; Peart, WS; Renzini, V | 1 |
| Ellis, FH; Hallermann, FJ; McCallister, BD; Pairolero, PC; Titus, JL | 1 |
| Baumber, JS; Davis, JO; Johnson, JA; Schneider, EG | 1 |
| Tanz, RD | 1 |
| Nosaka, S; Okamoto, K | 1 |
| Michailov, ML; Nitschkoff, S; Pohl, J | 1 |
| Denning, GS; Fessler, DC; Masucci, FD; Pals, DT; Sipos, F | 1 |
| Fyhrquist, F; Goodfriend, T | 1 |
| DiBona, GF; Sawin, LL | 1 |
| Fekete, A; Rényi-Vámos, A; Szitás, A | 1 |
| Churilova, AI; Suchkov, VV | 1 |
| Burstyn, PG; Horrobin, DF; Lloyd, IJ | 1 |
| Dennison, BH; Fuqua, JM; Hastings, FW; Malinin, TI; Speaker, DM; Weber, KT | 1 |
| Fukiyama, K; Omae, T | 1 |
| Baumann, H; Grieger, F; Wolf, I | 1 |
| Davis, JO; Johnson, JA; Prewitt, RL; Shade, RE; Witty, RT | 1 |
| Bernstein, MR; Hower, RD; Reichle, FA; Reichle, RM; Rosemond, GP | 1 |
| Brunner, HB; Gavras, H; Laragh, JH; Vaughan, ED | 1 |
| Baumann, H; Engler, E; Matthias, D; Wolf, I | 1 |
| Arora, KK; Brooks, B; Muirhead, EE | 1 |
| Dinsdale, HB; Haas, RA; Robertson, DM | 2 |
| Davis, JO; Freeman, RH; Johnson, JA; Spielman, WS | 1 |
| Ettinger, PO; Haider, B; Khan, MI; Lyons, MM; Oldewurtel, HA; Regan, TJ | 1 |
| Nitschkoff, S | 1 |
| Whitaker, AN | 1 |
| Brunner, HR; Gavras, H | 1 |
149 review(s) available for angiotensin ii and Disease Models, Animal
| Article | Year |
|---|---|
Twenty Years of Studying AngII (Angiotensin II)-Induced Abdominal Aortic Pathologies in Mice: Continuing Questions and Challenges to Provide Insight Into the Human Disease.
Topics: Age Factors; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Female; Heart Disease Risk Factors; Humans; Hypercholesterolemia; Male; Mice; Mice, Transgenic; Models, Cardiovascular; Receptors, Angiotensin; Sex Factors | 2022 |
Coronavirus Disease 2019: The Role of the Fibrinolytic System from Transmission to Organ Injury and Sequelae.
Topics: Angiotensin II; Animals; Antifibrinolytic Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Disease Models, Animal; Fibrinolysin; Fibrinolysis; Humans; Lung; Multiple Organ Failure; Pandemics; Plasminogen Activator Inhibitor 1; Pneumonia, Viral; Renin-Angiotensin System; SARS-CoV-2; Thrombophilia; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2020 |
Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Betacoronavirus; Bradykinin; Chick Embryo; Coronavirus Infections; COVID-19; Disease Models, Animal; Humans; Kininogens; Mice; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Pulmonary Edema; Renin-Angiotensin System; SARS-CoV-2 | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Endoplasmic Reticulum Stress, a Driver or an Innocent Bystander in Endothelial Dysfunction Associated with Hypertension?
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endoplasmic Reticulum Stress; Endothelium, Vascular; Humans; Hypertension; Vascular Diseases | 2017 |
Animal models in the research of abdominal aortic aneurysms development.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Female; Genetic Predisposition to Disease; Hemodynamics; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phenotype; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sus scrofa; Vascular Remodeling | 2017 |
Atrial thrombogenesis in atrial fibrillation : Results from atrial fibrillation models and AF-patients.
Topics: Age Factors; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticoagulants; Atrial Appendage; Atrial Fibrillation; Atrial Remodeling; Disease Models, Animal; Endocardium; Heart Atria; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice, Transgenic; Platelet Activation; Risk Assessment; Thromboembolism | 2018 |
Pathogenic and Therapeutic Significance of Angiotensin II Type I Receptor in Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Clinical Trials as Topic; Disease Models, Animal; Disease Progression; Humans; Receptor, Angiotensin, Type 1; Telmisartan; Valsartan | 2018 |
Therapeutic Vaccines for Hypertension: a New Option for Clinical Practice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Oligopeptides; Vaccines | 2018 |
Cognitive benefits of angiotensin IV and angiotensin-(1-7): A systematic review of experimental studies.
Topics: Angiotensin I; Angiotensin II; Animals; Cognition Disorders; Databases, Bibliographic; Dementia; Disease Models, Animal; Humans; Memory, Short-Term; Peptide Fragments | 2018 |
Intratubular and intracellular renin-angiotensin system in the kidney: a unifying perspective in blood pressure control.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Humans; Kidney; Kidney Tubules, Proximal; Liver; Mice; Renin; Renin-Angiotensin System | 2018 |
Regulation of sympathetic vasomotor activity by the hypothalamic paraventricular nucleus in normotensive and hypertensive states.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cardiovascular System; Disease Models, Animal; Excitatory Postsynaptic Potentials; Exercise Therapy; GABAergic Neurons; Glutamic Acid; Humans; Hypertension; Inflammation Mediators; Neural Inhibition; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Synaptic Transmission; Vasomotor System | 2018 |
[Behavioral and Molecular Pharmacological Study of the Role of Angiotensin II in Spinal Pain Transmission].
Topics: Angiotensin II; Animals; Brain; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain; Pain Perception; Peptidyl-Dipeptidase A; Phosphorylation; Spinal Cord; Synaptic Transmission; Up-Regulation | 2018 |
Temporal Frame of Immune Cell Infiltration during Heart Failure Establishment: Lessons from Animal Models.
Topics: Angiotensin II; Animals; Aorta; B-Lymphocytes; Cardiomegaly; Cell Movement; Constriction, Pathologic; Cytokines; Disease Models, Animal; Endomyocardial Fibrosis; Heart Failure; Humans; Hypertension; Mice; Monocytes; T-Lymphocytes; Time Factors; Ventricular Dysfunction, Left | 2018 |
The (pro)renin receptor: an emerging player in hypertension and metabolic syndrome.
Topics: Angiotensin II; Animals; Autophagy; Blood Pressure; Disease Models, Animal; Glucose; Humans; Hypertension; Lipid Metabolism; Metabolic Syndrome; Proton-Translocating ATPases; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Vacuolar Proton-Translocating ATPases; Wnt Signaling Pathway | 2019 |
[Renal adaptation after experimental nephrectomy in animals: a review].
Topics: Angiotensin II; Animals; Disease Models, Animal; Glomerular Filtration Rate; Hypertrophy; Insulin-Like Growth Factor I; Kidney; Kidney Glomerulus; Nephrectomy; Recovery of Function; Transforming Growth Factor beta1; Vasoconstrictor Agents | 2013 |
Animal models of scleroderma: current state and recent development.
Topics: Angiotensin II; Animals; Disease Models, Animal; DNA Topoisomerases, Type I; Fos-Related Antigen-2; Genetic Predisposition to Disease; Mice; Mice, Transgenic; Mutation; Proto-Oncogene Protein c-fli-1; Reactive Oxygen Species; Scleroderma, Systemic | 2013 |
Recent progress in the treatment of cardiovascular disease using olmesartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Coronary Artery Disease; Coronary Stenosis; Disease Models, Animal; Humans; Hypertension; Imidazoles; Plaque, Atherosclerotic; Tetrazoles | 2014 |
Molecular mechanism of aggravation of hypertensive organ damages by short-term blood pressure variability.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Humans; Hypertension; Myocarditis; Myocardium; Rats; Receptors, Mineralocorticoid; Renin-Angiotensin System; Risk Factors; Signal Transduction; Time Factors; Ventricular Dysfunction | 2014 |
Angiotensin and neurovascular coupling: beyond hypertension.
Topics: Alzheimer Disease; Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertension; NADPH Oxidases; Neurovascular Coupling; Receptor, Angiotensin, Type 1 | 2015 |
The roles of sensitization and neuroplasticity in the long-term regulation of blood pressure and hypertension.
Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Central Nervous System; Disease Models, Animal; Genetic Predisposition to Disease; Heredity; Humans; Hypertension; Neuronal Plasticity; Renin-Angiotensin System; Risk Factors; Signal Transduction; Time Factors | 2015 |
Dissecting abdominal aortic aneurysm in Angiotensin II-infused mice: the importance of imaging.
Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Disease Models, Animal; Hematoma; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Mice; Tomography, X-Ray Computed | 2015 |
Monocytes, Macrophages and Other Inflammatory Mediators of Abdominal Aortic Aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Inflammation Mediators; Macrophages; Mice; Monocytes; Spleen | 2015 |
Angiotensin II and Abdominal Aortic Aneurysms: An update.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Humans; Mice; Molecular Targeted Therapy | 2015 |
Incidence, severity, mortality, and confounding factors for dissecting AAA detection in angiotensin II-infused mice: a meta-analysis.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Disease Models, Animal; Female; Incidence; Male; Mice; Mice, Inbred C57BL | 2015 |
Angiotensin-II, the Brain, and Hypertension: An Update.
Topics: Angiotensin II; Animals; Brain; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; Hypertension; Oxidative Stress; Renin-Angiotensin System; Transcription Factors | 2015 |
Atherosclerosis and aortic aneurysm - is inflammation a common denominator?
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Cytokines; Diet, Western; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Risk Factors; Sedentary Behavior; Smoking | 2016 |
Critical Appraisal of the Utility and Limitations of Animal Models of Scleroderma.
Topics: Angiotensin II; Animals; Bleomycin; Disease Models, Animal; Genetic Predisposition to Disease; Graft vs Host Disease; Mice; Mice, Transgenic; Reactive Oxygen Species; Scleroderma, Systemic | 2016 |
Therapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Thoracic; Aortic Dissection; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Losartan; Marfan Syndrome; Mechanoreceptors; Mice; Muscle, Smooth, Vascular; Signal Transduction; Transforming Growth Factor beta | 2017 |
Recent Advances in Immunity and Hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Hypertension, Pregnancy-Induced; Immune System; Immunity, Innate; Inflammation Mediators; Rats, Inbred SHR; Risk Factors; Signal Transduction; Sodium Chloride, Dietary | 2017 |
The functional role of the renin-angiotensin system in pregnancy and preeclampsia.
Topics: Angiotensin II; Animals; Autoantibodies; Calcium; Disease Models, Animal; Female; Humans; Peptidyl-Dipeptidase A; Placenta; Placenta Diseases; Plasminogen Activator Inhibitor 1; Pre-Eclampsia; Pregnancy; Reactive Oxygen Species; Renin-Angiotensin System; Thromboplastin; Vascular Endothelial Growth Factor Receptor-1 | 2008 |
The preclinical basis of the therapeutic evaluation of losartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Disease Models, Animal; Humans; Hypertension; Losartan; Rats; Rats, Inbred SHR; Renal Insufficiency; Renin-Angiotensin System | 1995 |
Angiotensin II vaccine: a novel approach in the treatment of hypertension.
Topics: Adult; Angiotensin II; Animals; Blood Pressure; Clinical Trials as Topic; Disease Models, Animal; Humans; Hypertension; Immunization; Models, Biological; Rats; Recombinant Proteins; Renin-Angiotensin System; Vaccination; Vaccines | 2008 |
ACE inhibitors and angiotensin II receptor antagonists in Crohn's disease management.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Crohn Disease; Disease Models, Animal; Gastrointestinal Tract; Humans; Mice; Renin-Angiotensin System | 2008 |
Angiotensin II signaling and its implication in erectile dysfunction.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Endothelium, Vascular; Erectile Dysfunction; Humans; Male; Muscle, Smooth; Nitric Oxide Synthase; Penis; Renin-Angiotensin System; rho-Associated Kinases; Signal Transduction; Sympathetic Nervous System; Vasoconstriction; Vasopressins | 2009 |
CYT-006-AngQb, a vaccine against angiotensin II for the potential treatment of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Injections; Oligopeptides; Patents as Topic; Treatment Outcome; Vaccines, Synthetic | 2009 |
Region-specific changes in sympathetic nerve activity in angiotensin II-salt hypertension in the rat.
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertension; Kidney; Muscle, Skeletal; Rats; Sodium Chloride, Dietary; Sympathetic Nervous System; Viscera | 2010 |
Angiotensin II, mechanotransduction, and pulsatile arterial hemodynamics in hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiac Output; Disease Models, Animal; Elasticity; Humans; Hypertension; Mechanotransduction, Cellular; Pulsatile Flow; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors; Treatment Outcome; Vascular Resistance | 2009 |
Antagonists of the renin-angiotensin system and the prevention of obesity.
Topics: Adipose Tissue; Adiposity; Angiotensin II; Angiotensinogen; Animals; Body Weight; Disease Models, Animal; Humans; Obesity; Receptors, Angiotensin; Renin-Angiotensin System | 2009 |
Large blood pressure variability and hypertensive cardiac remodeling--role of cardiac inflammation.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Humans; Hypertension; Macrophages; Myocarditis; Myocardium; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sympathectomy; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2009 |
Regulation of GPCR signaling in hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Disease Models, Animal; GTP-Binding Proteins; Humans; Hypertension; Prevalence; Receptor Protein-Tyrosine Kinases; Receptors, G-Protein-Coupled; Signal Transduction; United States; Vasoconstriction; Vasodilation | 2010 |
Renal interactions of renin-angiotensin system, nitric oxide and superoxide anion: implications in the pathophysiology of salt-sensitivity and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Kidney; Nitric Oxide; Oxidative Stress; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Superoxides | 2009 |
Renal infiltration of immunocompetent cells: cause and effect of sodium-sensitive hypertension.
Topics: Adult; Angiotensin II; Animals; Autoimmunity; Disease Models, Animal; Heat-Shock Proteins; Humans; Hypertension; Immunocompetence; Inflammation; Kidney; Middle Aged; Nephritis; Oxidative Stress; Rats; Sodium; Sodium, Dietary | 2010 |
Brain angiotensin peptides regulate sympathetic tone and blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Medulla Oblongata; Nitric Oxide; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Vasomotor System | 2010 |
TGF-β signaling in aortic aneurysm: another round of controversy.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Disease Models, Animal; Humans; Signal Transduction; Smad Proteins; Transforming Growth Factor beta | 2010 |
A transgenic mouse model for studying the role of the parathyroid hormone-related protein system in renal injury.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertrophy; Kidney Diseases; Mice; Mice, Transgenic; Parathyroid Hormone-Related Protein; Proteinuria | 2011 |
Animal models of pre-eclampsia.
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Disease Models, Animal; Endothelium; Female; Humans; Kidney Glomerulus; Placental Circulation; Pre-Eclampsia; Pregnancy; Vascular Endothelial Growth Factor Receptor-1 | 2011 |
Oxidative stress and endothelial dysfunction in cerebrovascular disease.
Topics: Alzheimer Disease; Amidohydrolases; Angiotensin II; Animals; Brain Ischemia; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Mitochondria; Nitric Oxide; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Prostaglandin-Endoperoxide Synthases; Reperfusion Injury; Stroke; Subarachnoid Hemorrhage; Superoxide Dismutase | 2011 |
Lessons on the pathogenesis of aneurysm from heritable conditions.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Disease Models, Animal; Elastin; Humans; Muscle, Smooth, Vascular; Transforming Growth Factor beta | 2011 |
Local ocular renin-angiotensin system - a target for glaucoma therapy?
Topics: Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Renin-Angiotensin System; Species Specificity | 2011 |
This is not Dr. Conn's aldosterone anymore.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cytochrome P-450 CYP11B2; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Gene Expression Regulation; Humans; Hyperaldosteronism; Inflammation Mediators; Kidney; Ligands; Mice; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Receptors, Mineralocorticoid; Signal Transduction; Time Factors | 2011 |
Complex pathologies of angiotensin II-induced abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Connective Tissue; Disease Models, Animal; Disease Progression; Female; Humans; Hypercholesterolemia; Male; Mice; Peptides; Renin-Angiotensin System; Time Factors | 2011 |
Translational success stories: angiotensin receptor 1 antagonists in heart failure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Drug Design; Heart Failure; Humans; Myocardium; Renin-Angiotensin System; Signal Transduction; Translational Research, Biomedical; Ventricular Function, Left | 2011 |
Intracardiac intracellular angiotensin system in diabetes.
Topics: Angiotensin II; Animals; Cricetinae; Diabetes Mellitus; Diabetic Cardiomyopathies; Disease Models, Animal; Heart; Hyperglycemia; Mice; Myocardium; Rats; Renin-Angiotensin System | 2012 |
Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model.
Topics: Angiotensin II; Animals; Cell Nucleus; Cytoplasm; Disease Models, Animal; Hypertension; In Vitro Techniques; Mice; Mice, Transgenic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2012 |
Relevance of angiotensin II-induced aortic pathologies in mice to human aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Disease Models, Animal; Humans; Mice; Renin-Angiotensin System; Species Specificity | 2011 |
[In vitro and in vivo pharmacological profiles of a novel angiotensin type 1-receptor blocker, azilsartan].
Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Hypertension; Insulin Resistance; Obesity; Oxadiazoles | 2012 |
Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II-induced abdominal aortic aneurysm in mice.
Topics: Adventitia; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Chemokine CCL2; Disease Models, Animal; Female; Fibroblasts; Humans; Hyperhomocysteinemia; Incidence; Interleukin-6; Male; Mice; Mice, Mutant Strains; Middle Aged; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; Risk Factors; Signal Transduction; Smad2 Protein; Smad3 Protein; Vasculitis; Vasoconstrictor Agents | 2012 |
[Alcohol and acute respiratory distress syndrome: casuality or causality?].
Topics: Adaptive Immunity; Alcohol-Related Disorders; Alcoholism; Angiotensin II; Animals; Blood-Air Barrier; Causality; Cilia; Comorbidity; Cytokines; Disease Models, Animal; Disease Susceptibility; Humans; Inflammation Mediators; Liver Diseases, Alcoholic; Lung; Oxidative Stress; Phagocytosis; Pneumonia, Bacterial; Pulmonary Surfactants; Respiratory Distress Syndrome; Risk; Sepsis; Water-Electrolyte Imbalance; Wounds and Injuries; Zinc | 2013 |
Sympathetic nervous system and hypertension.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Carotid Body; Disease Models, Animal; Humans; Hypertension; Kidney; Obesity; Rabbits; Rats; Sympathetic Nervous System; Vasoconstrictor Agents | 2013 |
Dopamine and the kidney: a role in hypertension?
Topics: Angiotensin II; Animals; Disease Models, Animal; Disease Progression; Dopamine; Female; Humans; Hypertension; Kidney Diseases; Male; Mice; Polymorphism, Genetic; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Dopamine; Renin-Angiotensin System; Sensitivity and Specificity; Sodium Chloride | 2003 |
Contribution of salt intake to insulin resistance associated with hypertension.
Topics: Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Humans; Hypertension; Insulin; Insulin Resistance; Oxidative Stress; Potassium, Dietary; Rats; Rats, Inbred Dahl; Signal Transduction; Sodium Chloride, Dietary | 2003 |
[Hemodynamic factors].
Topics: Angiotensin II; Animals; Diabetes Mellitus; Disease Models, Animal; Humans; Hypertension; Insulin; Insulin Resistance; Oxidative Stress; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Signal Transduction | 2003 |
[Angiotensin II in organ organopathy].
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertension | 2004 |
Mouse models of abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Calcium Chloride; Cholesterol; Disease Models, Animal; Extracellular Matrix Proteins; Female; Genetic Engineering; Genetic Predisposition to Disease; Humans; Hyperlipidemias; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Knockout; Mice, Mutant Strains; Models, Animal; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pancreatic Elastase; Protease Inhibitors; Receptors, LDL; Renin; Species Specificity | 2004 |
Angiotensin II, PPAR-gamma and atherosclerosis.
Topics: Angiotensin II; Animals; Arteriosclerosis; Blood Vessels; Disease Models, Animal; Humans; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2004 |
Oxidative stress in hypertension and chronic kidney disease: role of angiotensin II.
Topics: Angiotensin II; Animals; Cells, Cultured; Chronic Disease; Disease Models, Animal; Humans; Hypertension; Infusion Pumps; Kidney Diseases; Oxidative Stress; Sodium Chloride, Dietary | 2004 |
Angiotensin II-mediated development of vascular diseases.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Arteriosclerosis; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Humans; Hyperlipidemias; Macrophages; Vascular Diseases | 2004 |
Combined blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists.
Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Agents; Diabetic Nephropathies; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Heart Failure; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Proteinuria; Rats; Renin-Angiotensin System; Ventricular Dysfunction, Left | 2004 |
Exercise training and sympathetic regulation in experimental heart failure.
Topics: Angiotensin II; Animals; Baroreflex; Disease Models, Animal; Heart Failure; Nitric Oxide; Nitric Oxide Synthase; Physical Conditioning, Animal; Rabbits; Receptor, Angiotensin, Type 1; Sympathetic Nervous System | 2004 |
Nitric oxide, angiotensin II, and hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Prognosis; Renal Circulation; Renin-Angiotensin System; Risk Factors | 2004 |
The therapeutic potential of hepatocyte growth factor for myocardial infarction and heart failure.
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart Failure; Hepatocyte Growth Factor; Humans; Myocardial Infarction | 2004 |
[Responsible genes for proteinuria and concept of the treatment for proteinuria].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Monoclonal; Disease Models, Animal; Humans; Membrane Proteins; Nephrotic Syndrome; Proteins; Proteinuria; Rats | 2004 |
[Natriuretic peptides and cardiomyopathy].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Biomarkers; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Disease Models, Animal; Humans; Natriuretic Peptide, Brain | 2004 |
Oxidative-nitrosative stress in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Membrane Transport Proteins; NADPH Oxidases; Phosphoproteins; Poly(ADP-ribose) Polymerases; Polymorphism, Genetic; Reactive Oxygen Species; Signal Transduction | 2005 |
Chronically increased intrarenal angiotensin II causes nephropathy in an animal model of type 2 diabetes.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Blood Pressure; Chromatography; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Fibronectins; Glucose; Hyperglycemia; Immunoblotting; Insulin; Insulin Resistance; Kidney; Male; Models, Statistical; Obesity; Proteinuria; Radioimmunoassay; Rats; Rats, Zucker; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2006 |
Angiotensin II--nitric oxide interactions in the control of sympathetic outflow in heart failure.
Topics: Angiotensin II; Animals; Baroreflex; Cardiac Output, Low; Disease Models, Animal; Excitatory Postsynaptic Potentials; Exercise; Heart Failure; Hemodynamics; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Risk Factors; Sensitivity and Specificity; Sympathetic Nervous System | 2000 |
Cardiac sympathetic afferent reflexes in heart failure.
Topics: Afferent Pathways; Angiotensin II; Animals; Baroreflex; Bradykinin; Capsaicin; Cardiac Output, Low; Disease Models, Animal; Dogs; Heart; Heart Failure; Nitric Oxide; Reference Values; Sensitivity and Specificity; Sympathetic Nervous System | 2000 |
Molecular mechanisms and therapeutic strategies of chronic renal injury: role of rho-kinase in the development of renal injury.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; Fibrosis; Glomerulosclerosis, Focal Segmental; Hypertension; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Microcirculation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents | 2006 |
Molecular mechanisms and therapeutic strategies of chronic renal injury: physiological role of angiotensin II-induced oxidative stress in renal medulla.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aortic Valve Stenosis; Blood Pressure; Diffusion; Disease Models, Animal; Humans; Hypertension; Kidney Diseases; Kidney Medulla; Kidney Tubular Necrosis, Acute; Nitric Oxide; Oxidative Stress; Pressure; Rats; Rats, Inbred Dahl; Renal Circulation; Sodium Chloride, Dietary; Superoxides; Vasoconstrictor Agents | 2006 |
The renin-angiotensin system in lupus: physiology, genes and practice, in animals and humans.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Autoimmune Diseases; Disease Models, Animal; Female; Humans; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Mice; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Rheumatic Diseases | 2006 |
[Development of animal models for the metabolic syndrome with hypertension].
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Insulin Resistance; Metabolic Syndrome; Mice; Mutation; Obesity; Rats; Rats, Inbred SHR; Receptors, Cell Surface; Receptors, Leptin; Tumor Necrosis Factor-alpha | 2006 |
Renal hemodynamics and permselectivity.
Topics: Angiotensin II; Animals; Diffusion; Disease Models, Animal; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Glomerulus; Permeability; Pressure; Proteinuria; Rats | 1990 |
Lipids and diabetic nephropathy.
Topics: Angiotensin II; Animals; Apolipoproteins E; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Dyslipidemias; Glycation End Products, Advanced; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Polymorphism, Genetic; Safety | 2006 |
Pathological involvement of chymase-dependent angiotensin II formation in the development of cardiovascular disease.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Chymases; Cricetinae; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Myocardium | 2000 |
Sex differences in angiotensin II- induced hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Estrogens; Female; Hypertension; Infusions, Intravenous; Male; Mice; Nitric Oxide Synthase; Ovariectomy; Reactive Oxygen Species; Sex Characteristics; Testosterone; Vasoconstrictor Agents | 2007 |
[Role of oxidative stress in angiotensin II-induced heart failure].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Heart Failure; Oxidative Stress; Rats; Rats, Inbred Dahl | 2007 |
Nitric oxide and superoxide interactions in the kidney and their implication in the development of salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Disease Models, Animal; Dogs; Enzyme Inhibitors; Hypertension; Kidney; Mice; Natriuresis; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Sodium Chloride; Superoxides | 2007 |
The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Chronic Disease; Disease Models, Animal; Humans; Hypertension; Hypertension, Renal; Kidney; Kidney Diseases; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2007 |
A clinical approach in regression of glomerulosclerosis.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Disease Progression; Glomerulosclerosis, Focal Segmental; Humans; Plasminogen Activator Inhibitor 1; Rats; Renin-Angiotensin System | 2007 |
Androgens stimulate proximal tubule transport.
Topics: Androgens; Angiotensin II; Animals; Blood Pressure; Dihydrotestosterone; Disease Models, Animal; Hypertension; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Up-Regulation | 2008 |
[Clinical pharmacology of renin-angiotensin system].
Topics: Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Endothelium, Vascular; Fatty Acids, Nonesterified; Humans; Insulin Resistance; Renin-Angiotensin System | 2008 |
Angiotensin-converting enzyme inhibitors: biochemical properties and biological actions.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Disease Models, Animal; Heart Failure; Humans; Hypertension; Kidney; Oligopeptides; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Structure-Activity Relationship; Substrate Specificity | 1984 |
Hypertension, the adrenal and the kidney: lessons from pharmacologic interruption of the renin-angiotensin system.
Topics: Adrenal Glands; Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Angiotensins; Animals; Blood Pressure; Disease Models, Animal; Humans; Hydrocortisone; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Kidney; Renin; Saralasin; Teprotide | 1980 |
Peptidergic and catecholaminergic mechanisms in central blood pressure control.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Catecholamines; Disease Models, Animal; Epinephrine; Humans; Hypertension; Kinins; Neurotransmitter Agents; Norepinephrine; Peptides; Pressoreceptors; Rats; Substance P | 1980 |
Peripheral neurogenic factors in acute and chronic alterations of arterial pressure.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Catecholamines; Desoxycorticosterone; Disease Models, Animal; Humans; Hypertension; Neurons; Norepinephrine; Peripheral Nerves; Rats; Receptors, Adrenergic, beta; Renin-Angiotensin System; Sympathetic Nervous System | 1983 |
Neural mechanisms in hypertension.
Topics: Angiotensin II; Animals; Brain; Catecholamines; Disease Models, Animal; Humans; Hypertension; Hypothalamus, Anterior; Pressoreceptors; Receptors, Angiotensin; Reflex; Renin; Vasopressins | 1980 |
Pressor and subpressor angiotensin II administration. Two experimental models of hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Humans; Hypertension | 1995 |
Losartan in heart failure: preclinical experiences and initial clinical outcomes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Heart Failure; Hemodynamics; Humans; Imidazoles; Losartan; Rats; Receptors, Angiotensin; Sheep; Tetrazoles | 1994 |
Scorpion envenoming and the role of insulin.
Topics: Angiotensin II; Animals; Catecholamines; Disease Models, Animal; Electrolytes; Humans; Insulin; Insulin Secretion; Multiple Organ Failure; Scorpion Stings; Scorpion Venoms; Scorpions | 1994 |
Role of neurohormones in ventricular adaptation and failure.
Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Hormones; Humans; Myocardial Infarction; Ventricular Function, Left | 1994 |
Acute renal failure.
Topics: Acute Disease; Acute Kidney Injury; Adenosine; Age Factors; Angiotensin II; Animals; Animals, Newborn; Blood Flow Velocity; Calcium Channels; Disease Models, Animal; Endothelins; Free Radicals; Glomerular Filtration Rate; Humans; Hypoxia; Infant, Newborn; Rabbits; Reactive Oxygen Species; Renal Circulation; Risk Factors | 1993 |
Impact of renin-angiotensin system blockade on structure and function of glomerular membrane components in animal models of kidney disease.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Basement Membrane; Capillaries; Disease Models, Animal; Kidney Diseases; Kidney Glomerulus; Renin-Angiotensin System | 1996 |
Role of angiotensin II in diabetic nephropathy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Enalapril; Hemodynamics; Plasma Volume; Rats; Renin-Angiotensin System | 1997 |
Renal tubular hypertrophy induced by angiotensin II.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cells, Cultured; Disease Models, Animal; Disease Progression; Hypertrophy; Kidney Diseases; Kidney Tubules; Rats; Renin-Angiotensin System | 1997 |
Angiotensin II in renal fibrosis: should TGF-beta rather than blood pressure be the therapeutic target?
Topics: Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Humans; Hypertension, Renal; Kidney Diseases; Transforming Growth Factor beta | 1997 |
Novel angiotensin peptides regulate blood pressure, endothelial function, and natriuresis.
Topics: Angiotensin II; Animals; Blood Pressure; Clinical Trials as Topic; Disease Models, Animal; Endothelium, Vascular; Humans; Natriuresis; Rats; Reference Values; Renin-Angiotensin System | 1998 |
Role of angiotensin in the congenital anomalies of the kidney and urinary tract in the mouse and the human.
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Kidney; Mice; Mice, Knockout; Receptors, Angiotensin; Ureteral Obstruction | 1998 |
Captopril and angiotensin II receptor antagonist therapy in a pacing model of heart failure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Heart Failure; Humans | 1998 |
Life and death in the microcirculation: a role for angiotensin II.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension, Renal; Microcirculation; Rats; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Sodium, Dietary | 1998 |
[From the angiogenic response to ischemia to the validation of the concept of "therapeutic angiogenesis"].
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Disease Models, Animal; Endothelial Growth Factors; Humans; Lymphokines; Myocardial Ischemia; Neovascularization, Physiologic; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
The TGR(mRen2)27 transgenic rat model of hypertension.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Disease Models, Animal; Gene Expression; Hypertension; Kidney; Myocardium; Phenotype; Rats; Renin-Angiotensin System | 1998 |
Effect of treatment on survival in an animal model of chronic heart failure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cricetinae; Disease Models, Animal; Heart Failure; Humans; Isoquinolines; Quinapril; Renin-Angiotensin System; Tetrahydroisoquinolines | 1998 |
Endothelin in hypertension: a role for receptor antagonists?
Topics: Angiotensin II; Animals; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Heart; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Diseases; Rats; Vascular Diseases; Vasoconstrictor Agents | 1998 |
The benefits of angiotensin II receptor blockers in patients with renal insufficiency or failure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Disease Models, Animal; Humans; Hypertension; Losartan; Rats; Renal Insufficiency; Renin-Angiotensin System; Treatment Outcome | 1998 |
Angiotensin II and sympathoactivation in heart failure.
Topics: Angiotensin II; Animals; Clinical Trials as Topic; Disease Models, Animal; Heart Failure; Hemodynamics; Humans; Prognosis; Rats; Renin-Angiotensin System; Vasoconstrictor Agents | 1999 |
New insights into the pathogenesis of interstitial nephritis.
Topics: Angiotensin II; Animals; Antibody Formation; B-Lymphocytes; Chemokines; Disease Models, Animal; Humans; Immune Tolerance; Immunity, Cellular; Interferon-gamma; Kidney Tubules; Nephritis, Interstitial; Nitric Oxide; Proteinuria; Transforming Growth Factor beta | 1999 |
Pharmacology of eprosartan, an angiotensin II receptor antagonist: exploring hypotheses from clinical data.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Disease Models, Animal; Humans; Hypertension; Imidazoles; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes | 1999 |
Endothelin: role in experimental hypertension.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Fructose; Hypertension; Insulin Resistance; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Dahl; Rats, Inbred SHR | 2000 |
Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways.
Topics: Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Humans; Hypertension; Mice; Mice, Knockout; Mice, Transgenic; Nitric Oxide; Peptidyl-Dipeptidase A; Receptors, Dopamine; Receptors, Neuropeptide; Renin-Angiotensin System | 2000 |
Role of the sympathetic nervous system in human renovascular hypertension.
Topics: Adrenergic Fibers; Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Humans; Hypertension, Renovascular; Ischemia; Kidney; Neurons, Afferent; Prognosis; Renin-Angiotensin System; Sympathetic Nervous System | 2000 |
Malignant hypertension - the role of the paracrine renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Disease Models, Animal; Female; Humans; Hypertension, Malignant; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 2000 |
Kidney angiotensin receptors and their role in renal pathophysiology.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Disease Models, Animal; Humans; Hypertension, Renovascular; Kidney Diseases; Receptors, Angiotensin; Renin-Angiotensin System | 2000 |
Oxidative stress and vascular damage in hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Vessels; Cardiovascular Diseases; Disease Models, Animal; Estrogens; Gene Transfer Techniques; Humans; Hydrogen Peroxide; Hypertension; Mitochondria; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitrates; Nitric Oxide Synthase; Oxidative Stress; Rats; Reactive Oxygen Species; Renin-Angiotensin System; Risk Factors; Signal Transduction; Superoxide Dismutase; Vitamins; Xanthine Oxidase | 2001 |
The future of hypertension therapy: sense, antisense, or nonsense?
Topics: Adenoviridae; Adrenomedullin; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Animal; DNA, Antisense; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; HIV; Humans; Hypertension; Kallikreins; Luminescent Proteins; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptides; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retroviridae; Transfection | 2001 |
Enhanced angiotensin II activity in heart failure: reevaluation of the counterregulatory hypothesis of receptor subtypes.
Topics: Angiotensin II; Animals; Apoptosis; Disease Models, Animal; Heart; Heart Failure; Humans; Mice; Myocardium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction | 2001 |
Angiotensin receptor blockers and the kidney: possible advantages over ACE inhibition?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus; Disease Models, Animal; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Failure, Chronic; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2001 |
Intrarenal transport and vasoactive substances in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biological Transport; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY | 2001 |
Angiotensin II, TGF-beta and renal fibrosis.
Topics: Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Humans; Kidney; Kidney Diseases; Rats; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Transforming Growth Factor beta | 2001 |
Hemodynamic effects of angiotensin II in the kidney.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hemodynamics; Humans; Kidney; Rats; Renin-Angiotensin System; Sensitivity and Specificity; Vasoconstriction | 2001 |
Use of angiotensin II receptor blockers in animal models of atherosclerosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteriosclerosis; Cholesterol, LDL; Disease Models, Animal; Endothelium, Vascular; Hypertension; Nitric Oxide; Renin-Angiotensin System | 2002 |
Cerebral vasospasm.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Platelets; Carbon Dioxide; Catecholamines; Chlorpromazine; Disease Models, Animal; Disulfiram; Humans; Ischemic Attack, Transient; Muscle Relaxants, Central; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandins; Serotonin; Serotonin Antagonists; Tyramine | 1976 |
[Renovascular hypertension. Concepts and reality].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Disease Models, Animal; Dogs; Humans; Hypertension, Renal; Hypertension, Renovascular; Rats; Renal Artery; Renal Artery Obstruction; Renin | 1979 |
Peptides and psychoneuroendocrinology. A perspective.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Behavior; Disease Models, Animal; Gonadotropin-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Hypothalamus; Mental Disorders; Pituitary Gland; Research Design; Thyroid Gland; Vasopressins | 1978 |
The renin axis and vasoconstriction volume analysis for understanding and treating renovascular and renal hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Disease Models, Animal; Diuresis; Humans; Hypertension, Renal; Ischemia; Kidney; Natriuresis; Propranolol; Rats; Renal Artery Obstruction; Renin; Secretory Rate; Snake Venoms; Vasomotor System | 1975 |
The pathogenesis of chronic renovascular hypertension.
Topics: Angiotensin II; Animals; Body Fluids; Cardiac Output; Chronic Disease; Disease Models, Animal; Homeostasis; Humans; Hypertension, Renal; Kallikreins; Kidney Medulla; Kinins; Muscle, Smooth; Prostaglandins A; Prostaglandins E; Renal Artery Obstruction; Renin; Sympathetic Nervous System; Transplantation, Autologous; Transplantation, Homologous | 1977 |
Experimental toxemia of pregnancy: review and speculation.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Dogs; Endocrine Glands; Female; Humans; Hypertension; Immunity; Ischemia; Kidney; Kidney Glomerulus; Liver; Placenta; Pre-Eclampsia; Pregnancy; Progesterone; Proteinuria; Rabbits; Rats; Renin; Uterus | 1977 |
Vasospasm: an update.
Topics: Angiotensin II; Animals; Blood; Cerebral Angiography; Cerebral Arteries; Diagnosis, Differential; Disease Models, Animal; Dopamine; Epinephrine; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Norepinephrine; Oxyhemoglobins; Physical Stimulation; Prostaglandins; Reserpine; Serotonin; Subarachnoid Hemorrhage; Syndrome | 1979 |
The renal circulation in hypertensive disease.
Topics: Angiotensin II; Animals; Body Fluids; Disease Models, Animal; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Kidney; Microcirculation; Rats; Regional Blood Flow; Sodium; Vasoconstrictor Agents; Vasodilator Agents | 1976 |
New concepts of the renin system and of vasoconstriction-volume mechanisms. Diagnosis and treatment of renovascular and renal hypertensions.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Humans; Hypertension, Renal; Propranolol; Renal Artery Obstruction; Renin; Sodium; Vasomotor System; Water-Electrolyte Balance | 1975 |
ACE-inhibitors and atherosclerosis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Diseases; Arteriosclerosis; Captopril; Cilazapril; Disease Models, Animal; Haplorhini; Hyperlipidemias; Lipid Metabolism; Peptidyl-Dipeptidase A; Pyridazines; Rabbits; Rats | 1992 |
Brain angiotensin: receptors, actions and possible role in hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Disease Models, Animal; Hypertension; Receptors, Angiotensin | 1992 |
Role of neuroendocrine mechanisms in the pathogenesis of heart failure.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Disease Models, Animal; Dogs; Heart Failure; Renin; Sympathetic Nervous System | 1991 |
The roles of angiotensin II and prostaglandins in the regulation of the glomerular filtration of albumin.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Glomerulus; Prostaglandins; Rats; Urodynamics | 1990 |
Issues surrounding a local cardiac renin system and the beneficial actions of angiotensin-converting enzyme inhibitors in ischemic myocardium.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Dogs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardial Infarction; Rats; Renin-Angiotensin System | 1990 |
Hypertension and the kidney: lessons learned from transplantation.
Topics: Angiotensin II; Animals; Disease Models, Animal; Graft Occlusion, Vascular; Graft Rejection; Humans; Hypertension; Hypertension, Renovascular; Kidney; Kidney Transplantation; Postoperative Complications; Rats; Steroids | 1987 |
Pathophysiology of experimental renovascular hypertension.
Topics: Acute Disease; Angiotensin II; Animals; Arterial Occlusive Diseases; Central Nervous System; Chronic Disease; Disease Models, Animal; Dogs; Hemodynamics; Hypertension, Renovascular; Kidney; Ouabain; Perfusion; Rats; Renin-Angiotensin System; Sympathetic Nervous System; Vasoconstriction; Vasopressins | 1985 |
[Experimental neurogenic hypertension].
Topics: Angiotensin II; Animals; Aorta; Autonomic Nervous System; Blood Pressure; Brachiocephalic Trunk; Carotid Arteries; Catecholamines; Cats; Cerebral Ventricles; Disease Models, Animal; Dogs; Haplorhini; Hemodynamics; Hot Temperature; Hypertension; Kaolin; Methods; Rabbits; Rats; Subclavian Artery; Sympathectomy; Vascular Diseases | 1972 |
Agents which block the action of the renin-angiotensin system.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Hydrocortisone; Hyperaldosteronism; Hypertension, Renal; Immune Sera; Immunization; Kidney; Peptides; Rats; Regional Blood Flow; Renin | 1974 |
5 trial(s) available for angiotensin ii and Disease Models, Animal
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Atorvastatin; Biomarkers; Cardiomegaly; Cells, Cultured; Cholesterol; Cholesterol, LDL; Coronary Vessels; Cross-Over Studies; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanine Nucleotide Exchange Factors; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Mice; Mice, Knockout; Neuropeptides; Oxidative Stress; Phosphatidylinositol 3-Kinase; Pravastatin; Proto-Oncogene Proteins c-akt; Pyrroles; Quinolines; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RNA Interference; Signal Transduction; Transfection | 2013 |
Myeloperoxidase is increased in human cerebral aneurysms and increases formation and rupture of cerebral aneurysms in mice.
Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Intracranial Aneurysm; Leukocyte Count; Male; Mice; Mice, Knockout; Pancreatic Elastase; Peroxidase; Vascular Cell Adhesion Molecule-1; Vasoconstrictor Agents | 2015 |
A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibody Specificity; Antihypertensive Agents; Autoantibodies; Blood Pressure; Disease Models, Animal; Double-Blind Method; Drug Evaluation, Preclinical; Humans; Hypertension; Male; Mice; Mice, Inbred BALB C; Middle Aged; Patient Compliance; Ramipril; Rats; Rats, Inbred SHR; Reference Values; Time Factors; Vaccines; Virion | 2007 |
Scorpion envenoming and the role of insulin.
Topics: Angiotensin II; Animals; Catecholamines; Disease Models, Animal; Electrolytes; Humans; Insulin; Insulin Secretion; Multiple Organ Failure; Scorpion Stings; Scorpion Venoms; Scorpions | 1994 |
2080 other study(ies) available for angiotensin ii and Disease Models, Animal
| Article | Year |
|---|---|
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
Baicalin attenuates angiotensin II-induced blood pressure elevation and modulates MLCK/p-MLC signaling pathway.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Calcium Signaling; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Flavonoids; Hypertension; Hypoglycemic Agents; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Rats, Wistar | 2021 |
Angiotensin-(3-7) alleviates isoprenaline-induced cardiac remodeling via attenuating cAMP-PKA and PI3K/Akt signaling pathways.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Agents; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Fibrosis; Isoproterenol; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Peptide Fragments; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Ventricular Remodeling | 2021 |
Angiotensin IV attenuates diabetic cardiomyopathy
Topics: Angiotensin II; Animals; Apoptosis; Autophagy; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Forkhead Box Protein O1; Glucose; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Quinolones; Signal Transduction; Streptozocin; Ventricular Dysfunction, Left | 2021 |
Overexpression of dimethylarginine dimethylaminohydrolase 1 protects from angiotensin II-induced cardiac hypertrophy and vascular remodeling.
Topics: Amidohydrolases; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Enzyme Induction; Fibrosis; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Transgenic; Time Factors; Vascular Remodeling; Vasodilation; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Aqueous extract of Solanum nigrum attenuates Angiotensin-II induced cardiac hypertrophy and improves cardiac function by repressing protein kinase C-ζ to restore HSF2 deSUMOlyation and Mel-18-IGF-IIR signaling suppression.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiotonic Agents; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Heat-Shock Proteins; Hypertension; Male; Myoblasts, Cardiac; Plant Extracts; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, IGF Type 2; Solanum nigrum; Transcription Factors | 2022 |
Inhibition on CXCL5 reduces aortic matrix metalloproteinase 9 expression and protects against acute aortic dissection.
Topics: Angiotensin II; Animals; Aorta; Aortic Dissection; Chemokine CXCL5; Disease Models, Animal; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL | 2021 |
Catalpol Alleviates Ang II-Induced Renal Injury Through NF-κB Pathway and TGF-β1/Smads Pathway.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Cell Line; Disease Models, Animal; Fibrosis; Humans; Inflammation Mediators; Iridoid Glucosides; Kidney; Male; Mice; Mice, Inbred C57BL; Nephritis; NF-kappa B; Rats; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1 | 2022 |
Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Choline O-Acetyltransferase; Disease Models, Animal; Heart Rate; Humans; Hypertension; Male; Mice, Inbred C57BL; Nitric Oxide; Polyethylene Glycols; Recombinant Proteins; Vasodilation | 2021 |
Characterization of a murine model of endothelial dysfunction induced by chronic intraperitoneal administration of angiotensin II.
Topics: Angiotensin II; Animals; Disease Models, Animal; Endothelium, Vascular; Infusions, Parenteral; Intercellular Adhesion Molecule-1; Interleukins; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vascular Diseases; Vascular Remodeling | 2021 |
miR-10b promotes aortic aneurysm formation and aortic rupture in angiotensin II-induced ApoE-deficient mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; MicroRNAs | 2021 |
Tianma Gouteng Decoction regulates oxidative stress and inflammation in AngII-induced hypertensive mice via transcription factor EB to exert anti-hypertension effect.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blood Pressure; Disease Models, Animal; Drugs, Chinese Herbal; Gene Knockdown Techniques; Heart Rate; Hypertension; Inflammation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Vascular Remodeling | 2022 |
Rosmarinic Acid Suppresses Abdominal Aortic Aneurysm Progression in Apolipoprotein E-deficient Mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Cinnamates; Depsides; Disease Models, Animal; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Rosmarinic Acid | 2022 |
STING protects against cardiac dysfunction and remodelling by blocking autophagy.
Topics: Angiotensin II; Animals; Apoptosis; Autophagy; Autophagy-Related Protein-1 Homolog; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Heart Failure; Humans; Membrane Proteins; Mice; Myocytes, Cardiac; Protective Agents; Signal Transduction; Sirolimus | 2021 |
Angiotensin II is a crucial factor in retinal aneurysm formation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood-Retinal Barrier; Blotting, Western; Coloring Agents; Disease Models, Animal; Fluorescein Angiography; Indocyanine Green; Interleukin-1beta; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Platelet-Derived Growth Factor beta; Retinal Arterial Macroaneurysm; Retinal Artery; Tetrazoles; Tomography, Optical Coherence; Vasoconstrictor Agents | 2021 |
ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury.
Topics: Acute Lung Injury; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Cricetinae; Disease Models, Animal; Female; Humans; Lung; Lung Injury; Male; Mice; Mice, Transgenic; Pulmonary Edema; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vero Cells; Virus Internalization | 2021 |
In Vivo Renin Activity Imaging in the Kidney of Progeroid
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; DNA Damage; DNA Repair; DNA-Binding Proteins; Endonucleases; Female; Gene Expression Regulation; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Losartan; Male; Mice; Mice, Knockout; Progeria; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Signal Transduction | 2021 |
The relationship of telmisartan with sclerostin in the osteoporosis model induced by ovariectomy in rats.
Topics: Adaptor Proteins, Signal Transducing; Alkaline Phosphatase; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Bone Density; Bone Density Conservation Agents; Bone Morphogenetic Proteins; Disease Models, Animal; Estrogens; Female; Genetic Markers; Osteocalcin; Osteogenesis; Osteopontin; Osteoporosis; Ovariectomy; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Tartrate-Resistant Acid Phosphatase; Telmisartan | 2021 |
The Receptor AT1 Appears to Be Important for the Maintenance of Bone Mass and AT2 Receptor Function in Periodontal Bone Loss Appears to Be Regulated by AT1 Receptor.
Topics: Alveolar Bone Loss; Angiotensin II; Animals; Disease Models, Animal; Male; Mandibular Diseases; Mice; Mice, Knockout; Periodontitis; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2021 |
Angiotensin Type 2 and Mas Receptor Activation Prevents Myocardial Fibrosis and Hypertrophy through the Reduction of Inflammatory Cell Infiltration and Local Sympathetic Activity in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Hypertension; Imidazoles; Injections, Intraperitoneal; Losartan; Male; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Tyrosine 3-Monooxygenase | 2021 |
MiR-410-3p facilitates Angiotensin II-induced cardiac hypertrophy by targeting Smad7.
Topics: 3' Untranslated Regions; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; HEK293 Cells; Humans; MicroRNAs; Myocytes, Cardiac; Primary Cell Culture; Rats; Smad7 Protein; Up-Regulation | 2022 |
AIM2 Inflammasome Activation Contributes to Aortic Dissection in a Sporadic Aortic Disease Mouse Model.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Aortic Dissection; Caspase 1; Disease Models, Animal; DNA-Binding Proteins; Humans; Inflammasomes; Mice; Mice, Inbred C57BL | 2022 |
Loss of the Protective Effect of Estrogen Contributes to Maternal Gestational Hypertension-Induced Hypertensive Response Sensitization Elicited by Postweaning High-Fat Diet in Female Offspring.
Topics: Angiotensin II; Animals; Diet, High-Fat; Disease Models, Animal; Estrogens; Female; Hypertension, Pregnancy-Induced; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2022 |
Platelet protects angiotensin II-driven abdominal aortic aneurysm formation through inhibition of inflammation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Platelets; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout | 2022 |
Angiotensin II enhances group 2 innate lymphoid cell responses via AT1a during airway inflammation.
Topics: Angiotensin II; Animals; Biomarkers; Bronchial Hyperreactivity; Disease Models, Animal; Disease Susceptibility; Immunity, Innate; Inflammation; Interleukin-33; Lymphocyte Subsets; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Respiratory Tract Diseases | 2022 |
Stromal cell-derived factor-1 exerts opposing roles through CXCR4 and CXCR7 in angiotensin II-induced adventitial remodeling.
Topics: Adventitia; Angiotensin II; Animals; Benzylamines; Cell Movement; Cell Proliferation; Chemokine CXCL12; Collagen; Cyclams; Disease Models, Animal; Fibroblasts; Fibrosis; Hypertension; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, CXCR; Receptors, CXCR4; Signal Transduction; Wound Healing | 2022 |
Allergic asthma aggravates angiotensin Ⅱ-induced cardiac remodeling in mice.
Topics: Angiotensin II; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cardiovascular Diseases; Disease Models, Animal; Heart Failure; Immunoglobulin E; Mice; Mice, Inbred BALB C; Nutrition Surveys; Ovalbumin; Ventricular Remodeling | 2022 |
Exacerbation of Thrombotic Responses to Silver Nanoparticles in Hypertensive Mouse Model.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Fibrinogen; Hypertension; Male; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Oxidative Stress; Partial Thromboplastin Time; Platelet Aggregation; Polyethylene Glycols; Prothrombin Time; Silver; von Willebrand Factor | 2022 |
Reduced blood pressure in sickle cell disease is associated with decreased angiotensin converting enzyme (ACE) activity and is not modulated by ACE inhibition.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diastole; Disease Models, Animal; Female; Humans; Hydroxyurea; Male; Mice; Mice, Inbred C57BL; Middle Aged; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Renin; Renin-Angiotensin System; Systole; Young Adult | 2022 |
mTOR inhibition prevents angiotensin II-induced aortic rupture and pseudoaneurysm but promotes dissection in Apoe-deficient mice.
Topics: Aneurysm, False; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Aortic Rupture; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; MTOR Inhibitors; RNA; TOR Serine-Threonine Kinases | 2022 |
CCN2 (Cellular Communication Network Factor 2) Deletion Alters Vascular Integrity and Function Predisposing to Aneurysm Formation.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Connective Tissue Growth Factor; Disease Models, Animal; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction; Up-Regulation | 2022 |
Trimethylamine N-Oxide Promotes Abdominal Aortic Aneurysm Formation by Aggravating Aortic Smooth Muscle Cell Senescence in Mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Disease Models, Animal; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle | 2022 |
Second Heart Field-Derived Cells Contribute to Angiotensin II-Mediated Ascending Aortopathies.
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Proteomics; Receptor, Transforming Growth Factor-beta Type II; RNA, Messenger; Transforming Growth Factors | 2022 |
Comparative analysis of hypertensive nephrosclerosis in animal models of hypertension and its relevance to human pathology. Glomerulopathy.
Topics: Angiotensin II; Animals; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Humans; Hypertension; Hypertension, Renal; Male; Nephritis; Nephrosclerosis; Rats; Rats, Inbred SHR; Vasoconstrictor Agents | 2022 |
Tolvaptan reduces angiotensin II-induced experimental abdominal aortic aneurysm and dissection.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Tolvaptan | 2022 |
Short-Term Pharmacological Induction of Arterial Stiffness and Hypertension with Angiotensin II Does Not Affect Learning and Memory and Cerebral Amyloid Load in Two Murine Models of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloidogenic Proteins; Amyloidosis; Angiotensin II; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypertension; Mice; Vascular Stiffness | 2022 |
Adipocyte-Derived Serum Amyloid A Promotes Angiotensin II-Induced Abdominal Aortic Aneurysms in Obese C57BL/6J Mice.
Topics: Adipocytes; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Doxycycline; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Obesity; Serum Amyloid A Protein | 2022 |
Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma.
Topics: Angiotensin II; Animals; Caspase 8; Disease Models, Animal; Glaucoma; Hypotension; Intraocular Pressure; Necroptosis; Neuroglia; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Tumor Necrosis Factor-alpha | 2022 |
Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin-Deficient Mice.
Topics: Angiotensin II; Animals; Aortic Dissection; Aortic Rupture; Disease Models, Animal; Elastin; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteoprotegerin; RANK Ligand | 2022 |
Cysteine-rich protein 2 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Cysteine; Disease Models, Animal; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle | 2022 |
Calcitriol Supplementation Protects Against Apoptosis and Alleviates the Severity of Abdominal Aortic Aneurysm Induced by Angiotensin II and Anti-TGFβ.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Calcitriol; Dietary Supplements; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Transforming Growth Factor beta | 2022 |
Single-Cell RNA Sequencing Technology Revealed the Pivotal Role of Fibroblast Heterogeneity in Angiotensin II-Induced Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Endothelial Cells; Fibroblasts; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Sequence Analysis, RNA | 2022 |
Tumor Necrosis Factor-
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Inflammation; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Statin therapy protects against abdominal aortic aneurysms by inducing the accumulation of regulatory T cells in ApoE
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Dysbiosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Knockout; Simvastatin; T-Lymphocytes, Regulatory | 2022 |
Postnatal Deletion of Bmal1 in Cardiomyocyte Promotes Pressure Overload Induced Cardiac Remodeling in Mice.
Topics: Angiotensin II; Animals; ARNTL Transcription Factors; Cardiomegaly; Disease Models, Animal; Fibrosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Ventricular Remodeling | 2022 |
Metabolomic Profiling of Angiotensin-II-Induced Abdominal Aortic Aneurysm in Ldlr
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Energy Metabolism; Glutamine; Glycine; Hypercholesterolemia; Hyperlipidemias; Lipids; Metabolomics; Mice; Mice, Inbred C57BL; Nitric Oxide; Receptors, LDL | 2022 |
ANGPTL8 is a negative regulator in pathological cardiac hypertrophy.
Topics: Angiopoietin-Like Protein 8; Angiopoietin-like Proteins; Angiotensin II; Animals; Antigens, CD; Cardiomegaly; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Heart Failure; Humans; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Peptide Hormones; Proto-Oncogene Proteins c-akt; Rats; Receptors, Immunologic; Signal Transduction | 2022 |
Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2.
Topics: Aconitate Hydratase; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Citric Acid Cycle; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Receptor Subfamily 1, Group D, Member 1 | 2022 |
Renin-Angiotensin System in Huntington's Disease: Evidence from Animal Models and Human Patients.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Humans; Huntington Disease; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2022 |
Of Mouse and Man: Cross-Species Characterization of Hypertensive Cardiac Remodeling.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Heart; Humans; Hypertension; Mice; Myocardium; Myocytes, Cardiac; Ventricular Remodeling | 2022 |
miR-21 upregulation exacerbates pressure overload-induced cardiac hypertrophy in aged hearts.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Humans; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Myocytes, Cardiac; Up-Regulation; Ventricular Remodeling | 2022 |
Gain-of-function, focal segmental glomerulosclerosis Trpc6 mutation minimally affects susceptibility to renal injury in several mouse models.
Topics: Albuminuria; Angiotensin II; Animals; Disease Models, Animal; Gain of Function Mutation; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Kidney Diseases; Mice; Mutation; Podocytes; TRPC6 Cation Channel | 2022 |
Genetic Deletion of Galectin-3 Exacerbates Age-Related Myocardial Hypertrophy and Fibrosis in Mice.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Galectin 3; Gene Deletion; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Sirtuin 1; Transforming Growth Factor beta; Ventricular Remodeling | 2022 |
Pharmaceutical Potential of Casein-Derived Tripeptide Met-Lys-Pro: Improvement in Cognitive Impairments and Suppression of Inflammation in APP/PS1 Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Caseins; Cognitive Dysfunction; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidases; Oligopeptides; Pharmaceutical Preparations; Presenilin-1; Receptors, Angiotensin; Tumor Necrosis Factor-alpha | 2022 |
Broad-acting therapeutic effects of miR-29b-chitosan on hypertension and diabetic complications.
Topics: Angiotensin II; Animals; Chitosan; Diabetes Complications; Diabetes Mellitus; Disease Models, Animal; Fibrosis; Humans; Hypertension; Mice; Mice, Inbred Strains; Mice, Knockout, ApoE; MicroRNAs; Thiolester Hydrolases | 2022 |
Angiotensin II enhances bacterial clearance via myeloid signaling in a murine sepsis model.
Topics: Angiotensin II; Animals; Bacteremia; Disease Models, Animal; Mice; Mice, Inbred C57BL; Myeloid Cells; Norepinephrine; Receptor, Angiotensin, Type 1; Sepsis; Signal Transduction | 2022 |
Drug Treatment by Central Venous Catheter in a Mouse Model of Angiotensin II Induced Abdominal Aortic Aneurysm and Monitoring by 3D Ultrasound.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Catheterization; Central Venous Catheters; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Ultrasonography | 2022 |
Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Angiotensinogen; Animals; Aortic Aneurysm, Thoracic; Aortic Rupture; Dilatation, Pathologic; Disease Models, Animal; Irbesartan; Losartan; Lysine; Male; Mice; Mice, Inbred C57BL; Protein-Lysine 6-Oxidase; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2022 |
BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Epigenesis, Genetic; Homeostasis; Humans; Inflammation; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle | 2022 |
Moxifloxacin induces aortic aneurysm and dissection by increasing osteopontin in mice.
Topics: Angiotensin II; Animals; Anti-Bacterial Agents; Aortic Aneurysm; Aortic Dissection; Disease Models, Animal; Elastin; Eosine Yellowish-(YS); Hematoxylin; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Moxifloxacin; Muscle Proteins; Myocytes, Smooth Muscle; Osteopontin; Rubber; Water | 2022 |
Myocardial effects of angiotensin II compared to norepinephrine in an animal model of septic shock.
Topics: Angiotensin II; Animals; Disease Models, Animal; Interleukin-1beta; Interleukin-6; Myocardium; Norepinephrine; Receptors, Interleukin-1; RNA, Messenger; Shock, Septic; Swine | 2022 |
Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; COVID-19; Cricetinae; Cytokines; Diet; Disease Models, Animal; Dyslipidemias; Humans; Inflammation; Mesocricetus; Non-alcoholic Fatty Liver Disease; Obesity; SARS-CoV-2 | 2022 |
EZH2 Regulates ANXA6 Expression via H3K27me3 and Is Involved in Angiotensin II-Induced Vascular Smooth Muscle Cell Senescence.
Topics: Angiotensin II; Animals; Cellular Senescence; Disease Models, Animal; Histones; Interleukin-8; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proteome; Reactive Oxygen Species; RNA, Messenger; Tumor Suppressor Protein p53 | 2022 |
Overexpressed DDX3x promotes abdominal aortic aneurysm formation and activates AKT in ApoE knockout mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; DEAD-box RNA Helicases; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Proto-Oncogene Proteins c-akt | 2022 |
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease Models, Animal; Elastin; Humans; Inflammation; Matrix Metalloproteinase 8; Mice; Mice, Knockout; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2022 |
Smooth Muscle Cell Relaxation Worsens Aortic Dilatation and Clinical Presentation in a BAPN/Angiotensin II-Induced Aortic Dissection Model in Rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Dilatation; Disease Models, Animal; Humans; Mice; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley | 2022 |
LOX-1 deficiency increases ruptured abdominal aortic aneurysm via thinning of adventitial collagen.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atherosclerosis; Collagen; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Scavenger Receptors, Class E | 2023 |
Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Folic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Nifedipine | 2022 |
Attenuation of Smooth Muscle Cell Phenotypic Switching by Angiotensin 1-7 Protects against Thoracic Aortic Aneurysm.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Phenotype | 2022 |
ADAR1 Non-Editing Function in Macrophage Activation and Abdominal Aortic Aneurysm.
Topics: Adenosine Deaminase; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; I-kappa B Kinase; Inflammation; Macrophage Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; NF-kappa B; RNA-Binding Proteins | 2023 |
Renin-angiotensin-aldosterone system function in the pig-to-baboon kidney xenotransplantation model.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Kidney; Papio; Potassium; Renin; Renin-Angiotensin System; Sodium; Swine; Transplantation, Heterologous | 2023 |
Administration of anti-inflammatory M2 macrophages suppresses progression of angiotensin II-induced aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm; Disease Models, Animal; Macrophages; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha | 2023 |
Interleukin-38 suppresses abdominal aortic aneurysm formation in mice by regulating macrophages in an IL1RL2-p38 pathway-dependent manner.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Interleukins; Macrophages; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Receptors, Interleukin | 2023 |
Hyperuricemia exacerbates abdominal aortic aneurysm formation through the URAT1/ERK/MMP-9 signaling pathway.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Hyperuricemia; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mice; Reactive Oxygen Species; Retrospective Studies; Signal Transduction; Uric Acid | 2023 |
Smooth muscle angiotensin II type 1A receptor is required for abdominal aortic aneurysm formation induced by angiotensin II plus β-aminopropionitrile.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Muscle, Smooth; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1 | 2023 |
Netrin-1 Monoclonal Antibody-Functionalized Nanoparticle Loaded with Metformin Prevents the Progression of Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Nanoparticles; Netrin-1; Phenotype | 2023 |
Targeting mitochondrial stress with Szeto-Schiller 31 prevents experimental abdominal aortic aneurysm: Crosstalk with endoplasmic reticulum stress.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Endoplasmic Reticulum Stress; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Reactive Oxygen Species | 2023 |
Gramine protects against pressure overload-induced pathological cardiac hypertrophy through Runx1-TGFBR1 signaling.
Topics: Angiotensin II; Animals; Cardiomegaly; Core Binding Factor Alpha 2 Subunit; Disease Models, Animal; Indole Alkaloids; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Rats; Receptor, Transforming Growth Factor-beta Type I; Signal Transduction; Transforming Growth Factor beta | 2023 |
CARMA3 Deficiency Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysm Development Interacting Between Endoplasmic Reticulum and Mitochondria.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; CARD Signaling Adaptor Proteins; Disease Models, Animal; Endoplasmic Reticulum; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria | 2023 |
Taxifolin ameliorates abdominal aortic aneurysm by preventing inflammation and apoptosis and extracellular matrix degradation via inactivating TLR4/NF-κB axis.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Disease Models, Animal; Extracellular Matrix; Humans; Inflammation; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; NF-kappa B; Toll-Like Receptor 4 | 2023 |
TRIM-containing 44 aggravates cardiac hypertrophy via TLR4/NOX4-induced ferroptosis.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Ferroptosis; Mice; Mice, Knockout; Myocytes, Cardiac; NADPH Oxidase 4; Toll-Like Receptor 4 | 2023 |
Tributyrin Intake Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm in
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Elastin; Epigenesis, Genetic; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout | 2023 |
Characterization of a robust mouse model of heart failure with preserved ejection fraction.
Topics: Angiotensin II; Animals; Cardiomyopathies; Disease Models, Animal; Fibrosis; Heart Failure; Mice; Phenylephrine; Stroke Volume; Ventricular Function, Left | 2023 |
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Scavenger | 2023 |
ANGPTL8 deletion attenuates abdominal aortic aneurysm formation in ApoE-/- mice.
Topics: Angiopoietin-Like Protein 8; Angiotensin II; Animals; Aorta; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Peptide Hormones | 2023 |
The Histone Methyltransferase SETDB2 Modulates Tissue Inhibitors of Metalloproteinase-Matrix Metalloproteinase Activity During Abdominal Aortic Aneurysm Development.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Histone Methyltransferases; Histones; Humans; Janus Kinases; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Tissue Inhibitor of Metalloproteinase-3 | 2023 |
Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Body Weight; Disease Models, Animal; Disulfiram; Gasdermins; Male; Mice; Mice, Inbred C57BL | 2023 |
Plasma Lipidomics Analysis Reveals the Potential Role of Lysophosphatidylcholines in Abdominal Aortic Aneurysm Progression and Formation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomarkers; Disease Models, Animal; Lipidomics; Lysophosphatidylcholines; Mice; Mice, Inbred C57BL | 2023 |
CD147 monoclonal antibody attenuates abdominal aortic aneurysm formation in angiotensin II-Infused apoE
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Proteomics | 2023 |
Vascular Ultrasound for In Vivo Assessment of Arterial Pathologies in a Murine Model of Atherosclerosis and Aortic Aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atherosclerosis; Carotid Intima-Media Thickness; Collagen; Disease Models, Animal; Mice; Mice, Inbred C57BL | 2023 |
Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis Regulatory Proteins; Disease Models, Animal; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Reactive Oxygen Species | 2023 |
Melanocortin-4 receptor in macrophages attenuated angiotensin II-induced abdominal aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Leptin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Obesity; Phosphatidylinositol 3-Kinases; Receptor, Melanocortin, Type 4 | 2023 |
Effect of Hydralazine on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Deficient Mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins; Apolipoproteins E; Apoptosis; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout | 2023 |
Involvement of an IgE/Mast cell/B cell amplification loop in abdominal aortic aneurysm progression.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Immunoglobulin E; Interleukin-4; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE | 2023 |
EZH2 as a novel therapeutic target for atrial fibrosis and atrial fibrillation.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Disease Models, Animal; Dogs; Enhancer of Zeste Homolog 2 Protein; Female; Fibroblasts; Fibrosis; Gene Expression Regulation; Heart Atria; Humans; Indoles; Male; Mice; Middle Aged; Pyridones | 2019 |
Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Agents; Case-Control Studies; Cells, Cultured; Disease Models, Animal; Drug Repositioning; Fibrosis; Gene Expression Regulation; Heart Failure; Humans; Integrin alphaVbeta3; Male; Mice; Myocytes, Cardiac; Neovascularization, Physiologic; Recovery of Function; Signal Transduction; Snake Venoms; Transcriptome | 2019 |
Novel Role for Pleckstrin Homology-Like Domain Family A, Member 3 in the Regulation of Pathological Cardiac Hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Gene Knockout Techniques; Glycogen Synthase Kinase 3 beta; Humans; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Myocytes, Cardiac; Nuclear Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Transgenic; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Ventricular Remodeling | 2019 |
Augmenting Renal Lymphatic Density Prevents Angiotensin II-Induced Hypertension in Male and Female Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Hypertension; Kidney; Lymphangiogenesis; Lymphatic Vessels; Macrophages, Peritoneal; Male; Mice, Inbred C57BL; Mice, Transgenic; Spleen; Vascular Endothelial Growth Factor D | 2020 |
Role of a RhoA/ROCK-Dependent Pathway on Renal Connexin43 Regulation in the Angiotensin II-Induced Renal Damage.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Connexin 43; Creatinine; Disease Models, Animal; Gene Expression Regulation; Kidney Diseases; Male; Oxidative Stress; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Time Factors | 2019 |
ATRQβ-001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Calcium Phosphates; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteopontin; Random Allocation; Vaccines, Virus-Like Particle; Vasoconstrictor Agents | 2019 |
Pharmacological inhibition of Notch signaling regresses pre-established abdominal aortic aneurysm.
Topics: ADP-ribosyl Cyclase 1; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Cells, Cultured; Collagen; Cytokines; Dipeptides; Disease Models, Animal; Extracellular Matrix; Gene Expression Regulation; Humans; Male; Membrane Glycoproteins; Mice; Myocytes, Smooth Muscle; Receptors, Notch; Signal Transduction | 2019 |
A knock-in mutation at cysteine 144 of TRIM72 is cardioprotective and reduces myocardial TRIM72 release.
Topics: Angiotensin II; Animals; Cardiomegaly; Coronary Artery Disease; Cysteine; Disease Models, Animal; Gene Knock-In Techniques; Insulin Resistance; Membrane Proteins; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Myocardial Reperfusion Injury; Myocardium | 2019 |
ACE2 and ADAM17 Interaction Regulates the Activity of Presympathetic Neurons.
Topics: ADAM17 Protein; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autonomic Nervous System; Disease Models, Animal; Enzyme Activation; GABAergic Neurons; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Optogenetics; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Random Allocation; Renin-Angiotensin System | 2019 |
Brain Prostaglandin D2 Increases Neurogenic Pressor Activity and Mean Arterial Pressure in Angiotensin II-Salt Hypertensive Rats.
Topics: Angiotensin II; Animals; Arterial Pressure; Biomarkers; Brain; Chromatography, Liquid; Cyclooxygenase Inhibitors; Disease Models, Animal; Hypertension; Ketorolac; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Reference Values; Risk Assessment; Sodium Chloride, Dietary; Tandem Mass Spectrometry | 2019 |
miR-154-5p Functions as an Important Regulator of Angiotensin II-Mediated Heart Remodeling.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Disease Models, Animal; Male; Mice; MicroRNAs; Myocytes, Cardiac | 2019 |
A bivalent antihypertensive vaccine targeting L-type calcium channels and angiotensin AT
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channels, L-Type; Disease Models, Animal; Epitopes; Hypertension; Male; Mice, Inbred BALB C; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Vaccination; Vaccines, Combined; Vaccines, Virus-Like Particle | 2020 |
Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Angiotensin II; Animals; Disease Models, Animal; Female; Gene Knockout Techniques; Genetic Vectors; Humans; Hypertensive Retinopathy; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Proteasome Endopeptidase Complex; Protein Subunits; Proteolysis; Receptor, Angiotensin, Type 1; Signal Transduction | 2020 |
Deficiency of MicroRNA miR-1954 Promotes Cardiac Remodeling and Fibrosis.
Topics: Actins; Angiotensin II; Animals; bcl-2 Homologous Antagonist-Killer Protein; Cardiomegaly; Caspase 3; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Collagen Type IV; Connective Tissue Growth Factor; Disease Models, Animal; Fibrosis; High-Throughput Nucleotide Sequencing; Interleukin-6; Mice, Transgenic; MicroRNAs; Myocardium; Organ Size; S100 Calcium-Binding Protein A4; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thrombospondin 1; Transforming Growth Factor beta1; Up-Regulation; Ventricular Remodeling | 2019 |
Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway
Topics: Acriflavine; ADAM17 Protein; Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease Models, Animal; Disease Progression; HEK293 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophages; Male; Mice, Inbred C57BL; Up-Regulation | 2019 |
Central angiotensin II-Protein inhibitor of neuronal nitric oxide synthase (PIN) axis contribute to neurogenic hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Infusions, Intraventricular; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 2020 |
Angiotensin-(1-7) mitigated angiotensin II-induced abdominal aortic aneurysms in apolipoprotein E-knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Peptide Fragments | 2020 |
Memory and cerebrovascular deficits recovered following angiotensin IV intervention in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Angiotensin II; Animals; Disease Models, Animal; Hippocampus; Humans; Infusions, Intraventricular; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurovascular Coupling | 2020 |
Downregulation of Brain Gα12 Attenuates Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Disease Models, Animal; GTP-Binding Protein alpha Subunits, G12-G13; Hypertension; Male; Oligodeoxyribonucleotides; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Ligustrazine prevents basilar artery remodeling in two-kidney-two-clip renovascular hypertension rats via suppressing PI3K/Akt signaling.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelin-1; Hypertension, Renovascular; Ligation; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Pyrazines; Rats, Sprague-Dawley; Renal Artery; Signal Transduction; Temporal Arteries; Vascular Remodeling | 2020 |
IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development.
Topics: Aneurysm; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Cell Differentiation; Cytokines; Disease Models, Animal; Female; Hematopoietic Stem Cells; Interleukin-27; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Myeloid Cells; Myelopoiesis; Receptors, Interleukin; Signal Transduction | 2019 |
Female Mice Exhibit Abdominal Aortic Aneurysm Protection in an Established Rupture Model.
Topics: Administration, Oral; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Knockout, ApoE; Protective Factors; Sex Factors | 2020 |
Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Male; Mice, Inbred C57BL; Mice, Knockout; NAD; Niacin; Niacinamide; Receptors, G-Protein-Coupled; Receptors, LDL; Signal Transduction; Sirtuin 1 | 2020 |
Tubular injury triggers podocyte dysfunction by β-catenin-driven release of MMP-7.
Topics: Angiotensin II; Animals; beta Catenin; Cells, Cultured; Disease Models, Animal; Doxorubicin; Humans; Kidney Tubules; Male; Matrix Metalloproteinase 7; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Podocytes; Primary Cell Culture; Proteolysis; Rats; Renal Insufficiency, Chronic | 2019 |
Corosolic acid ameliorates cardiac hypertrophy via regulating autophagy.
Topics: AMP-Activated Protein Kinase Kinases; Angiotensin II; Animals; Autophagosomes; Autophagy; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Humans; Mice; Microtubule-Associated Proteins; Myocytes, Cardiac; Protein Kinases; Rats; Signal Transduction; Triterpenes | 2019 |
Blockade of angiotensin-converting enzyme or tumor necrosis factor-α reverses maternal high-fat diet-induced sensitization of angiotensin II hypertension in male rat offspring.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animal Nutritional Physiological Phenomena; Animals; Antihypertensive Agents; Blood Pressure; Brain; Captopril; Diet, High-Fat; Disease Models, Animal; Female; Hypertension; Male; Maternal Nutritional Physiological Phenomena; Pentoxifylline; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Renin-Angiotensin System; Tumor Necrosis Factor Inhibitors | 2020 |
Inhibition of microRNA-146a attenuated heart failure in myocardial infarction rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Antagomirs; Atrial Remodeling; Disease Models, Animal; Heart; Heart Failure; Humans; MicroRNAs; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Rats; Rats, Sprague-Dawley; Ventricular Function, Left; Ventricular Remodeling | 2019 |
Classical Dendritic Cells Mediate Hypertension by Promoting Renal Oxidative Stress and Fluid Retention.
Topics: Angiotensin II; Animals; Dendritic Cells; Disease Models, Animal; Hypertension; Kidney; Membrane Proteins; Mice; Mice, Knockout; Oxidative Stress; T-Lymphocytes | 2020 |
Steroidogenic acute regulatory protein/aldosterone synthase mediates angiotensin II-induced cardiac fibrosis and hypertrophy.
Topics: Adrenal Glands; Angiotensin II; Animals; Biomarkers; Biopsy; Cardiomegaly; Cardiomyopathies; Collagen; Cytochrome P-450 CYP11B2; Disease Models, Animal; Disease Susceptibility; Fibrosis; Immunohistochemistry; Macrophages; Male; Models, Biological; Myocardium; Myofibroblasts; Phosphoproteins; Rats; Receptor, Angiotensin, Type 1; Signal Transduction; Smad2 Protein; Smad3 Protein | 2020 |
Pharmacological myeloperoxidase (MPO) inhibition in an obese/hypertensive mouse model attenuates obesity and liver damage, but not cardiac remodeling.
Topics: Angiotensin II; Animals; Diet, High-Fat; Disease Models, Animal; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Intra-Abdominal Fat; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Peroxidase; Severity of Illness Index; Thioxanthenes; Ventricular Remodeling | 2019 |
IL-5 overexpression attenuates aortic dissection by reducing inflammation and smooth muscle cell apoptosis.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Dissection; Apoptosis; Case-Control Studies; Disease Models, Animal; Female; Humans; Inflammation; Interleukin-5; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; Myocytes, Smooth Muscle; Prognosis | 2020 |
Imaging cellular activity and proliferation in the aortic wall.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cell Proliferation; Dideoxynucleosides; Disease Models, Animal; Fluorine Radioisotopes; Male; Mice; Mice, Knockout, ApoE; Positron Emission Tomography Computed Tomography; Reproducibility of Results; Time Factors | 2021 |
When the CAR Targets Scar.
Topics: Angiotensin II; Animals; Cardiomyopathies; Disease Models, Animal; Fibrosis; Immunotherapy, Adoptive; Mice; Mice, Mutant Strains; Myocardium; Phenylephrine; Receptors, Chimeric Antigen | 2019 |
PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Topics: Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Fibrosis; Flow Cytometry; Gene Expression Regulation; Male; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; PTEN Phosphohydrolase; Rats; RNA; Vascular Diseases; Vascular Remodeling | 2020 |
AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Imidazoles; Kidney Failure, Chronic; Kidney Tubules; Losartan; Male; Mice; Necroptosis; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction | 2019 |
Myeloid Differentiation Protein 2 Mediates Angiotensin II-Induced Liver Inflammation and Fibrosis in Mice.
Topics: Angiotensin II; Animals; Chalcones; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Gene Knockout Techniques; Injections, Subcutaneous; Lymphocyte Antigen 96; Male; Mice; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2019 |
Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hypertrophy, Right Ventricular; Hypoxia; Male; Medicine, Tibetan Traditional; Peptide Fragments; Peptidyl-Dipeptidase A; Plant Preparations; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ventricular Remodeling | 2020 |
Involvement of phosphatase and tensin homolog-induced putative kinase 1/Parkin-mediated autophagy in angiotensin II-induced cardiac hypertrophy in C57BL/6 mice.
Topics: Angiotensin II; Animals; Apoptosis; Autophagy; Cardiomegaly; Disease Models, Animal; Echocardiography; Heart Ventricles; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; Protein Kinases; Ubiquitin-Protein Ligases | 2020 |
Depletion of CD11c+ cell attenuates progression of abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Dendritic Cells; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout | 2020 |
Sodium-glucose cotransporter 2 inhibitor Dapagliflozin attenuates diabetic cardiomyopathy.
Topics: Angiotensin II; Animals; Benzhydryl Compounds; Biomarkers; Blood Glucose; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Diabetes Mellitus; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Glucosides; Inflammation Mediators; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sodium-Glucose Transporter 2 Inhibitors; Sodium-Hydrogen Exchanger 1; Ventricular Function, Left | 2020 |
Losartan promotes myocardial apoptosis after acute myocardial infarction in rats through inhibiting Ang II-induced JAK/STAT pathway.
Topics: Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Disease Models, Animal; Injections, Intraperitoneal; Janus Kinase 2; Losartan; Male; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Wistar; STAT3 Transcription Factor | 2020 |
MiR-326 targets MDK to regulate the progression of cardiac hypertrophy through blocking JAK/STAT and MAPK signaling pathways.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Line; Disease Models, Animal; Disease Progression; Down-Regulation; Humans; Janus Kinases; Male; MAP Kinase Signaling System; Mice; MicroRNAs; Midkine; Myocytes, Cardiac; Rats; STAT Transcription Factors | 2020 |
Neuron-derived orphan receptor-1 modulates cardiac gene expression and exacerbates angiotensin II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Biomarkers; Cardiomegaly; Collagen; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Disease Progression; Electrocardiography; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Inflammation; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Nuclear Receptor Subfamily 4, Group A, Member 3; Transcription, Genetic; Ventricular Remodeling | 2020 |
Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Formaldehyde; Humans; Injections, Spinal; Male; Mice; Microglia; Neurons; Nociception; p38 Mitogen-Activated Protein Kinases; Pain; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Spinal Cord | 2020 |
Pro-Renin Receptor Overexpression Promotes Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-Knockout Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Cytokines; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Macrophages; Male; Matrix Metalloproteinases; Mice; Mice, Knockout, ApoE; Myocytes, Smooth Muscle; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Signal Transduction; Vacuolar Proton-Translocating ATPases | 2020 |
Alterations in gut microbiota of abdominal aortic aneurysm mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Bacteria; Disease Models, Animal; Dysbiosis; Feces; Gastrointestinal Microbiome; Intestines; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Ribotyping | 2020 |
Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways.
Topics: Amides; Angiotensin II; Animals; Apoptosis; Blotting, Western; Cardiomegaly; Disease Models, Animal; Fibrosis; Flow Cytometry; Fumarates; Isoproterenol; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy.
Topics: Acetylation; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Emodin; Female; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Rheum | 2020 |
High content screening identifies licoisoflavone A as a bioactive compound of Tongmaiyangxin Pills to restrain cardiomyocyte hypertrophy via activating Sirt3.
Topics: Acetylation; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Isoflavones; Isoproterenol; Male; Mice, Inbred C57BL; Mitochondria, Heart; Myocytes, Cardiac; Phenylephrine; Rats; Sirtuin 3 | 2020 |
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
Topics: Angiotensin II; Animals; Cell Cycle Proteins; Disease Models, Animal; Down-Regulation; Fibroblasts; Fibrosis; Gene Expression; Heart Atria; Humans; Kruppel-Like Transcription Factors; Mice; MicroRNAs; Myocardium; Repressor Proteins; Up-Regulation | 2020 |
Sex-specific computational models for blood pressure regulation in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Computer Simulation; Disease Models, Animal; Female; Homeostasis; Hypertension; Kidney; Male; Models, Cardiovascular; Natriuresis; Rats, Sprague-Dawley; Rats, Wistar; Renal Artery; Renal Circulation; Sex Characteristics; Sex Factors; Sodium Chloride, Dietary; Sympathetic Nervous System | 2020 |
The association between microRNA-21 and hypertension-induced cardiac remodeling.
Topics: Aged; Angiotensin II; Animals; Animals, Newborn; Apoptosis Regulatory Proteins; Cardiomegaly; Disease Models, Animal; Female; Fibrosis; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Middle Aged; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Signal Transduction; Transcription Factor AP-1; Transforming Growth Factor beta1 | 2020 |
Amphetamine-induced sensitization of hypertension and lamina terminalis neuroinflammation.
Topics: Amphetamine; Angiotensin II; Animals; Blood Pressure; Central Nervous System Stimulants; Diet, High-Fat; Disease Models, Animal; Hypertension; Hypothalamus; Inflammation; Paraventricular Hypothalamic Nucleus; Rats | 2020 |
T-cell senescence accelerates angiotensin II-induced target organ damage.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta; Cardiovascular Diseases; Cell Line; Disease Models, Animal; Homeodomain Proteins; Humans; Hypertension; Immunosenescence; Inflammation Mediators; Interferon-gamma; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Oxidative Stress; Phenotype; Superoxides; T-Lymphocytes; Time Factors | 2021 |
Targeting vascular smooth muscle cell dysfunction with xanthine derivative KMUP-3 inhibits abdominal aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Apoptosis Regulatory Proteins; Cells, Cultured; Disease Models, Animal; Male; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Piperidines; Rats, Sprague-Dawley; Signal Transduction; Vascular Calcification; Xanthines | 2020 |
AVE0991, a nonpeptide angiotensin-(1-7) mimic, inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Disease Models, Animal; Humans; Imidazoles; Immunohistochemistry; Lipids; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Molecular Mimicry; Myocytes, Smooth Muscle; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments | 2020 |
The 3' Untranslated Region Protects the Heart from Angiotensin II-Induced Cardiac Dysfunction via AGGF1 Expression.
Topics: 3' Untranslated Regions; Angiogenic Proteins; Angiotensin II; Animals; Cells, Cultured; Dependovirus; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Heart Diseases; Heart Function Tests; HEK293 Cells; Humans; Male; Mice; MicroRNAs; Myeloid Cell Leukemia Sequence 1 Protein; Myocytes, Cardiac | 2020 |
A novel STAT3 inhibitor attenuates angiotensin II-induced abdominal aortic aneurysm progression in mice through modulating vascular inflammation and autophagy.
Topics: Aminosalicylic Acids; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Apoptosis; Autophagy; Autophagy-Related Proteins; Cells, Cultured; Disease Models, Animal; Janus Kinase 2; Male; Mice, Knockout, ApoE; NF-kappa B; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Vascular Remodeling | 2020 |
Hyperlipidemia inhibits the protective effect of lisinopril after myocardial infarction via activation of dendritic cells.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Apolipoproteins E; Dendritic Cells; Disease Models, Animal; Heart; Humans; Hyperlipidemias; Lipoproteins, LDL; Lisinopril; Mice; Mice, Knockout; Myeloid Differentiation Factor 88; Myocardial Infarction; Myocardium; NF-kappa B; Signal Transduction; Toll-Like Receptor 4; Ventricular Remodeling | 2020 |
Nox2+ myeloid cells drive vascular inflammation and endothelial dysfunction in heart failure after myocardial infarction via angiotensin II receptor type 1.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Disease Models, Animal; Endothelial Cells; Heart Failure; Leukocyte Rolling; Macrophages; Male; Mice, Inbred C57BL; Monocytes; Muramidase; Myeloid Cells; Myocardial Infarction; NADPH Oxidase 2; Oxidative Stress; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Vasculitis | 2021 |
Role of ADAM9 and miR-126 in the development of abdominal aortic aneurysm.
Topics: 3' Untranslated Regions; ADAM Proteins; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Binding Sites; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation, Enzymologic; Macrophages; Male; Membrane Proteins; Mice, Knockout, ApoE; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction | 2020 |
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension, Renal; Mice; Mice, Knockout; Nephritis; Receptors, Adrenergic, alpha-2; Sympathectomy; Sympathetic Nervous System; Synaptic Transmission | 2020 |
LncRNA AK045171 protects the heart from cardiac hypertrophy by regulating the SP1/MG53 signalling pathway.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Down-Regulation; Membrane Proteins; Mice; Myocardium; Myocytes, Cardiac; RNA, Long Noncoding; Signal Transduction; Sp1 Transcription Factor | 2020 |
B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart Failure; Hypertension; Male; Mice; Mice, Inbred C57BL; Paenibacillus; Peptidyl-Dipeptidase A; Recombinant Proteins | 2020 |
STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stress.
Topics: Angiotensin II; Animals; Biomarkers; Cardiomegaly; Disease Models, Animal; Disease Susceptibility; Echocardiography; Endoplasmic Reticulum Stress; Fibrosis; Gene Expression; Gene Knockdown Techniques; Immunohistochemistry; Inflammation; Male; Membrane Proteins; Mice; Myocytes, Cardiac; Rats; Signal Transduction | 2020 |
Inhibition of histone demethylase JMJD1C attenuates cardiac hypertrophy and fibrosis induced by angiotensin II.
Topics: Aminopyridines; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart; Humans; Hydrazones; Jumonji Domain-Containing Histone Demethylases; Myocardium; Myocytes, Cardiac; Oxidoreductases, N-Demethylating; Rats; RNA, Small Interfering; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1 | 2020 |
Evaluation of a smart activatable MRI nanoprobe to target matrix metalloproteinases in the early-stages of abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Contrast Media; Disease Models, Animal; Ferric Compounds; Gene Expression Regulation; Humans; Magnetic Resonance Imaging; Matrix Metalloproteinases; Mice; Nanoparticles | 2020 |
Qian Yang Yu Yin Granule protects against hypertension-induced renal injury by epigenetic mechanism linked to Nicotinamide N-Methyltransferase (NNMT) expression.
Topics: Acetylation; Angiotensin II; Animals; Cell Proliferation; Cortactin; Disease Models, Animal; DNA Methylation; Drugs, Chinese Herbal; Epigenesis, Genetic; Epithelial Cells; HEK293 Cells; Histones; Humans; Hypertension; Kidney; Kidney Diseases; Male; Nicotinamide N-Methyltransferase; Rats, Inbred SHR; Rats, Inbred WKY; S-Adenosylhomocysteine; Sirtuin 1 | 2020 |
A Modified Murine Abdominal Aortic Aneurysm Rupture Model Using Elastase Perfusion and Angiotensin II Infusion.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Inflammation Mediators; Male; Mice, Inbred C57BL; Pancreatic Elastase; Time Factors; Vascular Remodeling | 2020 |
Plasma vasopressin levels are closely associated with fetal hypotension and neuronal injury after hypoxia-ischemia in near-term fetal sheep.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Biomarkers; Blood Gas Analysis; Disease Models, Animal; Female; Fetal Hypoxia; Hydrogen-Ion Concentration; Hypotension; Hypoxia-Ischemia, Brain; Male; Nervous System Diseases; Neurons; Sheep; Umbilical Cord; Vasopressins | 2020 |
Qingda granule inhibits angiotensin Ⅱ induced VSMCs proliferation through MAPK and PI3K/AKT pathways.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Vascular Remodeling | 2020 |
Apelin-13 alleviated cardiac fibrosis via inhibiting the PI3K/Akt pathway to attenuate oxidative stress in rats with myocardial infarction-induced heart failure.
Topics: Angiotensin II; Animals; Disease Models, Animal; Echocardiography; Fibroblasts; Fibrosis; Heart; Heart Failure; Humans; Injections, Intraperitoneal; Intercellular Signaling Peptides and Proteins; Male; Myocardial Infarction; Myocardium; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction | 2020 |
MRTF-A promotes angiotensin II-induced inflammatory response and aortic dissection in mice.
Topics: Angiotensin II; Animals; Aortic Dissection; Apoptosis; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Mice; Stress, Mechanical; Trans-Activators; Transcriptome; Tumor Necrosis Factor-alpha | 2020 |
Runx2 (Runt-Related Transcription Factor 2)-Mediated Microcalcification Is a Novel Pathological Characteristic and Potential Mediator of Abdominal Aortic Aneurysm.
Topics: Adult; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Case-Control Studies; Core Binding Factor Alpha 1 Subunit; Dilatation, Pathologic; Disease Models, Animal; Durapatite; Female; Humans; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Middle Aged; Signal Transduction; Vascular Calcification; Vascular Remodeling | 2020 |
CRISPR/Cas9-Mediated miR-29b Editing as a Treatment of Different Types of Muscle Atrophy in Mice.
Topics: Angiotensin II; Animals; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Dependovirus; Disease Models, Animal; Gene Editing; Genetic Therapy; HEK293 Cells; Humans; Immobilization; Injections, Intramuscular; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle Denervation; Muscular Atrophy; Myoblasts, Skeletal; RNA, Guide, Kinetoplastida; RNA, Messenger; Signal Transduction; Treatment Outcome | 2020 |
Altered heart rate variability in angiotensin II-mediated hypertension is associated with impaired autonomic nervous system signaling and intrinsic sinoatrial node dysfunction.
Topics: Angiotensin II; Animals; Autonomic Nervous System; Disease Models, Animal; Electrocardiography; Heart Atria; Heart Rate; Hypertension; Male; Mice; Mice, Inbred C57BL; Sick Sinus Syndrome; Sinoatrial Node | 2020 |
Effects of Estrogen on Cardiac mRNA and LncRNA Expression Profiles in Hypertensive Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression Profiling; Hypertension; Mice, Inbred C57BL; Myocytes, Cardiac; Ovariectomy; Oxidative Stress; RNA, Long Noncoding; RNA, Messenger; Transcriptome; Ventricular Remodeling | 2021 |
Polyphyllin I attenuates pressure over-load induced cardiac hypertrophy via inhibition of Wnt/β-catenin signaling pathway.
Topics: Angiotensin II; Animals; Cardiomegaly; Diosgenin; Disease Models, Animal; Echocardiography; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Wnt Signaling Pathway | 2020 |
MiR-144-5p limits experimental abdominal aortic aneurysm formation by mitigating M1 macrophage-associated inflammation: Suppression of TLR2 and OLR1.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Line; Cell Plasticity; Disease Models, Animal; Disease Susceptibility; Gene Expression; Humans; Inflammation; Macrophage Activation; Macrophages; Mice; Mice, Knockout; MicroRNAs; RAW 264.7 Cells; RNA Interference; Scavenger Receptors, Class E; Toll-Like Receptor 2 | 2020 |
Purinergic P2X
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Male; Purinergic P2X Receptor Antagonists; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Purinergic P2X1; Receptors, Purinergic P2X7; Signal Transduction | 2020 |
Factor XII blockade inhibits aortic dilatation in angiotensin II-infused apolipoprotein E-deficient mice.
Topics: ADAM17 Protein; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Factor XII; Mice | 2020 |
The protein Deleted in Breast Cancer-1 (DBC1) regulates vascular response and formation of aortic dissection during Angiotensin II infusion.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Cell Cycle Proteins; Cell Proliferation; Disease Models, Animal; Humans; Hypertension; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Nerve Tissue Proteins; Vascular Endothelial Growth Factor A; Vascular System Injuries | 2020 |
Collagen fibril abnormalities in human and mice abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Collagen; Disease Models, Animal; Extracellular Matrix; Humans; Mice; Mice, Knockout | 2020 |
Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Aminopropionitrile; Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cholesterol; Disease Models, Animal; Down-Regulation; Drug Evaluation, Preclinical; Gain of Function Mutation; Gene Expression Regulation; Genetic Vectors; Humans; Loss of Function Mutation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Transcriptome | 2020 |
A novel interaction between soluble epoxide hydrolase and the AT1 receptor in retinal microvascular damage.
Topics: Angiotensin II; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Epoxide Hydrolases; Mice; Mice, Inbred C57BL; Mice, Knockout; Microvessels; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Retina | 2020 |
Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm.
Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Case-Control Studies; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Dynamins; Humans; Leukocytes; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Mitochondria, Muscle; Mitochondrial Dynamics; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxygen Consumption; Phosphorylation; Quinazolinones | 2021 |
Therapeutic Effect of Rapamycin on Aortic Dissection in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Cell Cycle Checkpoints; Cell Line; Disease Models, Animal; Gefitinib; Gene Expression Regulation; Gene Ontology; Gene Regulatory Networks; Male; Mice; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; STAT3 Transcription Factor; TOR Serine-Threonine Kinases | 2020 |
Quercetin Dihydrate inhibition of cardiac fibrosis induced by angiotensin II in vivo and in vitro.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiomyopathies; Collagen Type I; Collagen Type III; Disease Models, Animal; Disease Progression; Fibroblasts; Fibrosis; Male; Mice; Mice, Inbred C57BL; Myocardium; Quercetin; Rats | 2020 |
AT2R agonist NP-6A4 mitigates aortic stiffness and proteolytic activity in mouse model of aneurysm.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice, Knockout; Osteopontin; Phenotype; Proteolysis; Receptor, Angiotensin, Type 2; Vascular Stiffness | 2020 |
MiR-126a-5p limits the formation of abdominal aortic aneurysm in mice and decreases ADAMTS-4 expression.
Topics: ADAMTS4 Protein; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Biopsy; Cells, Cultured; Disease Models, Animal; Disease Susceptibility; Extracellular Matrix; Gene Expression Regulation; Humans; Mice; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA Interference | 2020 |
Group V secreted phospholipase A
Topics: Angiotensin II; Animals; Aorta; Aortic Dissection; Disease Models, Animal; Endoplasmic Reticulum Stress; Group V Phospholipases A2; Linoleic Acid; Mice; Mice, Knockout; Oleic Acid; Phospholipids | 2020 |
Phosphoinositide 3-kinase γ deficiency attenuates kidney injury and fibrosis in angiotensin II-induced hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Disease Models, Animal; Fibroblasts; Fibrosis; Hypertension; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; T-Lymphocytes; Vasoconstrictor Agents | 2020 |
Intermedin alleviates pathological cardiac remodeling by upregulating klotho.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Constriction; Disease Models, Animal; Fibrosis; Glucuronidase; Hypertrophy, Left Ventricular; Klotho Proteins; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Neuropeptides; Peptide Hormones; Phosphorylation; PPAR gamma; Rats, Sprague-Dawley; Signal Transduction; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Paired box 6 inhibits cardiac fibroblast differentiation.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Differentiation; Chemokine CXCL10; Disease Models, Animal; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Gene Expression Regulation; Gene Knockdown Techniques; Introns; Male; Mice; Mice, Inbred C57BL; Myocardium; PAX6 Transcription Factor; Promoter Regions, Genetic; Protein Binding; Receptors, Interleukin-1 Type II; RNA, Messenger; RNA, Small Interfering; Transforming Growth Factor beta1 | 2020 |
FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway.
Topics: AMP-Activated Protein Kinase Kinases; Angiotensin II; Animals; Aorta; Cell Line; Disease Models, Animal; Fibronectins; Humans; Hypertension; Inflammasomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Protein Kinases; Rats; Signal Transduction; Sirtuin 1 | 2020 |
Rivaroxaban ameliorates angiotensin II-induced cardiac remodeling by attenuating TXNIP/Trx2 interaction in KKAy mice.
Topics: Angiotensin II; Animals; Carrier Proteins; Disease Models, Animal; Mice; Mice, Knockout; Rivaroxaban; Thioredoxins; Ventricular Remodeling | 2020 |
Neohesperidin inhibits cardiac remodeling induced by Ang II in vivo and in vitro.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hesperidin; Hypertrophy, Left Ventricular; Inflammation Mediators; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Repositioning of pentoxifylline as an immunomodulator and regulator of the renin-angiotensin system in the treatment of COVID-19.
Topics: Alveolar Epithelial Cells; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Complement Activation; COVID-19; COVID-19 Drug Treatment; Cytokines; Disease Models, Animal; Drug Repositioning; Endothelial Cells; Gene Expression Regulation; Humans; Immunologic Factors; Inflammation; Lymphocyte Subsets; Microcirculation; Oxidative Stress; Pandemics; Pentoxifylline; Rats; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2; Signal Transduction; Venous Thromboembolism | 2020 |
LncRNA LBX2-AS1 facilitates abdominal aortic aneurysm through miR-4685-5p/LBX2 feedback loop.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Disease Progression; Feedback, Physiological; Female; Gene Expression Regulation; Homeodomain Proteins; Humans; Mice; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; Signal Transduction | 2020 |
Diallyl Trisulfide Suppresses Angiotensin II-Induced Vascular Remodeling Via Inhibition of Mitochondrial Fission.
Topics: Allyl Compounds; Angiotensin II; Animals; Cell Movement; Cell Plasticity; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dynamins; Hypertension; Male; Mice, Inbred C57BL; Mitochondria, Muscle; Mitochondrial Dynamics; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Phosphorylation; Reactive Oxygen Species; rho-Associated Kinases; Signal Transduction; Sulfides; Vascular Remodeling | 2020 |
Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Carboxy-Lyases; China; Disease Models, Animal; Humans; Inflammation; Kelch-Like ECH-Associated Protein 1; Macrophages; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NF-E2-Related Factor 2; Succinates | 2020 |
Therapeutic Targeting of Interleukin-11 Signalling Reduces Pressure Overload-Induced Cardiac Fibrosis in Mice.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aorta; Arterial Pressure; Cardiomyopathies; Collagen; Constriction; Disease Models, Animal; Fibronectins; Fibrosis; Hydroxyproline; Interleukin-11; Male; Mice, Inbred C57BL; Myocardium; Signal Transduction | 2021 |
Class switching and high-affinity immunoglobulin G production by B cells is dispensable for the development of hypertension in mice.
Topics: Angiotensin II; Animals; Antibody Affinity; Aorta; Blood Pressure; Cells, Cultured; Cytidine Deaminase; Desoxycorticosterone Acetate; Disease Models, Animal; Female; Hypertension; Immunoglobulin Class Switching; Immunoglobulin G; Immunoglobulin Heavy Chains; Immunoglobulin M; Kidney; Male; Memory B Cells; Mice, Inbred C57BL; Mice, Knockout; Sodium Chloride, Dietary | 2021 |
Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cholesterol; Collagen Type I; Disease Models, Animal; Fibrosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; Osteoprotegerin; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2020 |
The CX3CL1/CX3CR1 axis is upregulated in chronic kidney disease and contributes to angiotensin II-induced migration of vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Cell Line; Cell Movement; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Disease Models, Animal; Interleukin-6; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proto-Oncogene Proteins c-akt; Renal Insufficiency, Chronic; Signal Transduction; Up-Regulation; Uremia | 2020 |
All-trans retinoic acid attenuates the progression of Ang II-induced abdominal aortic aneurysms in ApoE
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Tretinoin | 2020 |
Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice-Brief Report.
Topics: Amino Acid Substitution; Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Blood Pressure; Disease Models, Animal; Female; Hepatocytes; Humans; Hypertension; Male; Mice, Knockout; Plaque, Atherosclerotic; Receptors, LDL; Renin; Species Specificity | 2020 |
Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes.
Topics: Adult; Angiotensin II; Animals; Anticholesteremic Agents; Biopsy; Case-Control Studies; Cell Line; Cholesterol; Datasets as Topic; Disease Models, Animal; Female; Gene Expression Profiling; Humans; Lipid Metabolism; Male; Mice; Mice, Knockout; Middle Aged; Oligonucleotide Array Sequence Analysis; Podocytes; Renal Insufficiency, Chronic; Sirtuins | 2020 |
Nitroxide-enhanced MRI of cardiovascular oxidative stress.
Topics: Adenosine; Angiotensin II; Animals; Cardiovascular System; Cyclic N-Oxides; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Myocardial Infarction; Nitrogen Oxides; Obesity; Oxidative Stress; Perfusion; Pyrrolidines | 2020 |
Angiotensin II Infusion Leads to Aortic Dissection in LRP8 Deficient Mice.
Topics: Acetylcholine; Angiotensin II; Animals; Aortic Dissection; Blood Pressure; Bone Marrow Transplantation; Cell Adhesion; Chemotaxis, Leukocyte; Disease Models, Animal; Gene Expression Regulation; Infusion Pumps; LDL-Receptor Related Proteins; Male; Mice; Microscopy, Video; Myeloid Cells; Radiation Chimera; RNA, Messenger; Vasodilation | 2020 |
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.
Topics: Angiotensin II; Aniline Compounds; Animals; Apoptosis; Cardiac Pacing, Artificial; Cardiomegaly; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Fibrosis; Heart Failure; Inflammation Mediators; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Rats, Sprague-Dawley; Stroke Volume; Sulfonamides; Tachycardia, Ventricular; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Levistilide A reverses rat hepatic fibrosis by suppressing angiotensin II‑induced hepatic stellate cells activation.
Topics: Actins; Angiotensin II; Animals; Carbon Tetrachloride; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Hepatic Stellate Cells; Heterocyclic Compounds, Bridged-Ring; Liver Cirrhosis; Male; Rats; Receptor, Angiotensin, Type 1; Signal Transduction; Up-Regulation | 2020 |
Alamandine attenuates angiotensin II-induced vascular fibrosis via inhibiting p38 MAPK pathway.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertension; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling | 2020 |
Ex vivo magnetic particle imaging of vascular inflammation in abdominal aortic aneurysm in a murine model.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Feasibility Studies; Humans; Inflammation; Magnetic Iron Oxide Nanoparticles; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout, ApoE | 2020 |
The ACE2-deficient mouse: A model for a cytokine storm-driven inflammation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cells, Cultured; Chemokines; Cornea; COVID-19; Cytokine Release Syndrome; Disease Models, Animal; Epithelial Cells; Humans; Interleukins; Mice; Mice, Inbred C57BL; Mice, Knockout; SARS-CoV-2; THP-1 Cells; Tumor Necrosis Factor-alpha | 2020 |
Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling.
Topics: Aldehyde Dehydrogenase, Mitochondrial; Angiotensin II; Animals; Animals, Newborn; Aorta; Apoptosis; Base Sequence; Cardiotonic Agents; Constriction, Pathologic; Disease Models, Animal; Fibrosis; Heart Failure; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Membrane Proteins; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Myocytes, Cardiac; Nuclear Respiratory Factor 1; Pressure; Rats; Signal Transduction; Thioctic Acid | 2020 |
Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Disease Progression; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging, Cine; Male; Mice, Inbred C57BL; Myocardium; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Ubiquitin-specific protease 19 blunts pathological cardiac hypertrophy via inhibition of the TAK1-dependent pathway.
Topics: Angiotensin II; Animals; Animals, Newborn; Aortic Valve Stenosis; Cardiomegaly; CRISPR-Cas Systems; Disease Models, Animal; Endopeptidases; Fibrosis; Inflammation; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phenylephrine; Pressure; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Ubiquitin-Protein Ligases; Ventricular Remodeling | 2020 |
Recognizing the evolving and beneficial role of regulatory T cells in aneurysm growth.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Mice; T-Lymphocytes, Regulatory | 2020 |
Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cognitive Dysfunction; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Macrophages; Male; Mice; Microglia; Organic Chemicals | 2020 |
The effects of liraglutide and dapagliflozin on cardiac function and structure in a multi-hit mouse model of heart failure with preserved ejection fraction.
Topics: Angiotensin II; Animals; Benzhydryl Compounds; Blood Glucose; Diet, High-Fat; Disease Models, Animal; Female; Fibrosis; Gene Expression Regulation; Glucagon-Like Peptide-1 Receptor; Glucosides; Heart Failure, Diastolic; Hypertrophy, Left Ventricular; Incretins; Liraglutide; Mice, Inbred C57BL; Myocardium; Signal Transduction; Sodium-Glucose Transporter 2 Inhibitors; Ventricular Function, Left; Ventricular Remodeling | 2021 |
MicroRNA-132 attenuated cardiac fibrosis in myocardial infarction-induced heart failure rats.
Topics: Angiotensin II; Animals; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Echocardiography; Fibroblasts; Fibrosis; Heart; Heart Failure; Humans; Male; MicroRNAs; Myocardial Infarction; Myocardium; Primary Cell Culture; Rats; Signal Transduction | 2020 |
LncRNA SENCR suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Cells, Cultured; Disease Models, Animal; Down-Regulation; Extracellular Matrix; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; Signal Transduction; Tissue Inhibitor of Metalloproteinases | 2021 |
Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation.
Topics: Aging; Angiotensin II; Animals; Arteries; Arteritis; Bone Marrow; Bone Marrow Transplantation; Cell Differentiation; Cell Lineage; Disease Models, Animal; Female; Hematopoietic Stem Cells; Homeostasis; Humans; Macrophages; Male; Mice; Mice, Transgenic; Regeneration; RNA-Seq; Single-Cell Analysis; Transplantation Chimera | 2020 |
Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Biomarkers; Biopsy; Cell Adhesion Molecules; Cytokines; Disease Models, Animal; Disease Susceptibility; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Mice; Mice, Knockout; Models, Biological; Myocytes, Smooth Muscle; Peroxiredoxins; Reactive Oxygen Species; Ultrasonography | 2020 |
Deficiency in Aim2 affects viability and calcification of vascular smooth muscle cells from murine aortas and angiotensin-II induced aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Calcinosis; Cell Proliferation; Cell Survival; Cellular Senescence; Disease Models, Animal; Disease Susceptibility; DNA-Binding Proteins; Inflammasomes; Mice; Mice, Knockout; Myocytes, Smooth Muscle | 2020 |
Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Blood Pressure; Caloric Restriction; Cholecalciferol; Dietary Supplements; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Humans; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Up-Regulation; Vitamin D Deficiency | 2020 |
Early Morphofunctional Changes in AngII-Infused Mice Contribute to Regional Onset of Aortic Aneurysm and Dissection.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortography; Computed Tomography Angiography; Dilatation, Pathologic; Disease Models, Animal; Endothelium, Vascular; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Time Factors; Vascular Remodeling; Vasoconstriction; X-Ray Microtomography | 2020 |
Different reactive species modulate the hypotensive effect triggered by angiotensins at CVLM of 2K1C hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Heart Rate; Hypertension, Renovascular; Male; Medulla Oblongata; Peptide Fragments; Rats; Reactive Oxygen Species; Renin-Angiotensin System; Vasoconstrictor Agents | 2020 |
Caveolin‑1 modulates hypertensive vascular remodeling via regulation of the Notch pathway.
Topics: Angiotensin II; Animals; Brain; Caveolin 1; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Gene Expression Regulation; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Rats; Receptor, Notch1; Signal Transduction; Up-Regulation; Vascular Remodeling | 2020 |
Hypoxia in utero increases the risk of pulmonary hypertension in rat offspring and is associated with vasopressin type‑2 receptor upregulation.
Topics: Angiotensin II; Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription Factors; Biomarkers; Disease Models, Animal; Female; Fetal Hypoxia; Fetal Weight; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Pulmonary Arterial Hypertension; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Tumor Necrosis Factor-alpha; Up-Regulation | 2020 |
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Atherosclerosis; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Mice; Protein-Lysine 6-Oxidase; Quercetin | 2020 |
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.
Topics: Airway Remodeling; Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Female; Imidazoles; Inflammation Mediators; Lung; Macrophages, Alveolar; Mice, Inbred BALB C; Neutrophils; Oxidative Stress; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Smoke; Sulfonamides; Thiophenes; Tobacco Products | 2020 |
The beneficial effects of angiotensin-converting enzyme II (ACE2) activator in pulmonary hypertension secondary to left ventricular dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activators; Humans; Hypertension, Pulmonary; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Ventricular Dysfunction, Left | 2020 |
Prevention of Progression of Aortic Aneurysm by Peptide Vaccine Against Ang II (Angiotensin II) in a Rat Model.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Hemocyanins; Immunoconjugates; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Rats, Wistar; Signal Transduction; Vaccines, Subunit | 2020 |
Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish.
Topics: Adult; Amino Acid Substitution; Angiotensin II; Animals; Animals, Genetically Modified; Cardiomyopathy, Hypertrophic, Familial; Child; Chlorocebus aethiops; Connexin 43; Connexins; COS Cells; Disease Models, Animal; DNA Mutational Analysis; Doxorubicin; Female; Gap Junctions; Gene Knockout Techniques; Genetic Testing; Heart Transplantation; Humans; Induced Pluripotent Stem Cells; Male; Mice; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Pedigree; Primary Cell Culture; Protein Domains; Rats; Zebrafish; Zebrafish Proteins | 2020 |
Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)-Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cells, Cultured; Disease Models, Animal; Fibroblasts; Growth Differentiation Factor 6; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 2; Paracrine Communication; Signal Transduction; Vascular Remodeling | 2021 |
Comparative effects of angiotensin II on the contractility of muscularis mucosae and detrusor in the pig urinary bladder.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Male; Mucous Membrane; Muscle, Smooth; Swine; Urinary Bladder | 2021 |
Protectin DX promotes epithelial injury repair and inhibits fibroproliferation partly via ALX/PI3K signalling pathway.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Anaplastic Lymphoma Kinase; Angiotensin II; Animals; Apoptosis; Cytokines; Disease Models, Animal; Docosahexaenoic Acids; Inflammation Mediators; Lipopolysaccharides; Mice; Phosphatidylinositol 3-Kinases; Rats | 2020 |
Gal-1 (Galectin-1) Upregulation Contributes to Abdominal Aortic Aneurysm Progression by Enhancing Vascular Inflammation.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Case-Control Studies; Cells, Cultured; Cytokines; Disease Models, Animal; Disease Progression; Extracellular Matrix; Fibroblasts; Galectin 1; Humans; Inflammation Mediators; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout, ApoE; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction; Up-Regulation; Vascular Remodeling | 2021 |
The Possible Regulatory Mechanisms of Aqueous, Ethyl Acetate and NHexane Fractions of the Ribes khorassanicum Extract on Acute Hypertension in Rats.
Topics: Acetates; Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Disease Models, Animal; Hexanes; Hypertension; Losartan; Male; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats; Rats, Wistar; Ribes; Signal Transduction; Water | 2021 |
Blockade of ERK1/2 activation with U0126 or PEP7 reduces sodium appetite and angiotensin II-induced pressor responses in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Appetite; Butadienes; Captopril; Disease Models, Animal; Furosemide; Humans; Hypertension; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sodium | 2021 |
Deubiquitinase Ubiquitin-Specific Protease 10 Deficiency Regulates Sirt6 signaling and Exacerbates Cardiac Hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Culture Techniques; Disease Models, Animal; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Signal Transduction; Sirtuins; Ubiquitin Thiolesterase | 2020 |
Specific inhibition of SHP2 suppressed abdominal aortic aneurysm formation in mice by augmenting the immunosuppressive function of MDSCs.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Benzenesulfonates; Disease Models, Animal; Hydrazones; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Myeloid-Derived Suppressor Cells; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Signal Transduction | 2021 |
C-C chemokine receptor 5 signaling contributes to cardiac remodeling and dysfunction under pressure overload.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cardiomyopathies; Cell Line; Chemokines, CC; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Hypertrophy, Left Ventricular; Immunoglobulin G; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Rats; Receptors, CCR5; Signal Transduction; Ventricular Remodeling | 2021 |
Predator Scent-Induced Sensitization of Hypertension and Anxiety-like Behaviors.
Topics: Angiotensin II; Animals; Anxiety; Disease Models, Animal; Hypertension; Odorants; Rats; Rats, Sprague-Dawley | 2022 |
Cardiac Pressure Overload Decreases ETV1 Expression in the Left Atrium, Contributing to Atrial Electrical and Structural Remodeling.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Arrhythmias, Cardiac; Disease Models, Animal; DNA-Binding Proteins; Down-Regulation; Female; Heart Atria; Heart Failure; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Neuregulin-1; Receptor, Transforming Growth Factor-beta Type I; Transcription Factors; Ventricular Remodeling; Young Adult | 2021 |
Factor Xa inhibitor rivaroxaban suppresses experimental abdominal aortic aneurysm progression via attenuating aortic inflammation.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Calcium Chloride; Cell Adhesion Molecules; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Factor Xa Inhibitors; Humans; Inflammation Mediators; Male; Mice, Knockout, ApoE; Retrospective Studies; Rivaroxaban; Signal Transduction; Vascular Remodeling | 2021 |
SIRT3 Deficiency Sensitizes Angiotensin-II-Induced Renal Fibrosis.
Topics: Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Humans; Hypertension; Kidney; Kidney Diseases; Mice; Sirtuin 3 | 2020 |
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Topics: Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Fibrosis; Gallic Acid; Male; Mice, Inbred C57BL; MicroRNAs; Myocardial Infarction; Myocardium; Transforming Growth Factor beta; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Prevention of CaCl
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Chemokine CCL3; Disease Models, Animal; Humans; Inflammation Mediators; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Receptors, CCR1; Receptors, CCR5; Signal Transduction; Specific Pathogen-Free Organisms | 2020 |
A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs).
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Disease Models, Animal; Estradiol; Estrogens; Female; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Myeloid Cells | 2020 |
Melatonin alleviates angiotensin-II-induced cardiac hypertrophy via activating MICU1 pathway.
Topics: Angiotensin II; Animals; Antioxidants; Calcium-Binding Proteins; Cardiomegaly; Disease Models, Animal; Gene Knockdown Techniques; Heart; In Vitro Techniques; Melatonin; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Myocardium; Myocytes, Cardiac; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Vasoconstrictor Agents | 2020 |
SIRT3 (Sirtuin-3) Prevents Ang II (Angiotensin II)-Induced Macrophage Metabolic Switch Improving Perivascular Adipose Tissue Function.
Topics: Acetylation; Adipose Tissue, Brown; Angiotensin II; Animals; Cell Plasticity; Disease Models, Animal; Energy Metabolism; Fibrosis; HEK293 Cells; Humans; Hypertension; Inflammasomes; Interleukin-1beta; Lactic Acid; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Panniculitis; Phenotype; Pyruvate Dehydrogenase (Lipoamide); Signal Transduction; Sirtuin 3 | 2021 |
Chronically infused angiotensin II induces depressive-like behavior via microglia activation.
Topics: Angiotensin II; Animals; Behavior, Animal; Depressive Disorder; Disease Models, Animal; Hindlimb Suspension; Hippocampus; Humans; Hypothalamo-Hypophyseal System; Interleukin-1beta; Mice; Mice, Inbred C57BL; Microglia; Pituitary-Adrenal System; Stress, Psychological | 2020 |
Urinary DPP4 correlates with renal dysfunction, and DPP4 inhibition protects against the reduction in megalin and podocin expression in experimental CKD.
Topics: Angiotensin II; Animals; Biomarkers; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Fibrosis; Intracellular Signaling Peptides and Proteins; Kidney; Low Density Lipoprotein Receptor-Related Protein-2; Male; Membrane Proteins; Proteinuria; Rats, Wistar; Renal Insufficiency, Chronic; Retinol-Binding Proteins, Plasma; Signal Transduction; Sitagliptin Phosphate | 2021 |
The C57Bl/6J mouse strain is more susceptible to angiotensin II-induced aortic aneurysm formation than C57Bl/6N.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Phenotype | 2021 |
High NOR-1 (Neuron-Derived Orphan Receptor 1) Expression Strengthens the Vascular Wall Response to Angiotensin II Leading to Aneurysm Formation in Mice.
Topics: Aneurysm; Angiotensin II; Animals; Disease Models, Animal; DNA-Binding Proteins; Elastin; Inflammation; Matrix Metalloproteinases; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Oxidative Stress; Receptors, Steroid; Receptors, Thyroid Hormone; Signal Transduction | 2021 |
Establishment and effect evaluation of an aortic dissection model induced by different doses of β-aminopropionitrile in rats.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Magnetic Resonance Imaging; Male; Rats, Sprague-Dawley; Time Factors; Vascular Remodeling | 2021 |
HDAC5 inhibition reduces angiotensin II-induced vascular contraction, hypertrophy, and oxidative stress in a mouse model.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; Benzamides; Cells, Cultured; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxadiazoles; Oxidative Stress; rho-Associated Kinases; rhoA GTP-Binding Protein; Vascular Remodeling; Vasoconstriction | 2021 |
The Histamine 3 Receptor Is Expressed in the Heart and Its Activation Opposes Adverse Cardiac Remodeling in the Angiotensin II Mouse Model.
Topics: Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Inflammation; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Ventricular Remodeling | 2020 |
Qingda granule attenuates angiotensin II-induced cardiac hypertrophy and apoptosis and modulates the PI3K/AKT pathway.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Cell Line; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Gene Regulatory Networks; Hypertension; Hypertrophy, Left Ventricular; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction | 2021 |
Involvement of circHIPK3 in the pathogenesis of diabetic cardiomyopathy in mice.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Collagen Type I, alpha 1 Chain; Collagen Type III; Diabetic Cardiomyopathies; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression Regulation; Male; Mice, Inbred C57BL; MicroRNAs; Myocardium; RNA, Circular; Signal Transduction | 2021 |
Metabolic Disorders Induced by Fructosedrinking Water Affect Angiotensin II-mediated Intestinal Contractility in Male Wistar Rats.
Topics: Angiotensin II; Animals; Disease Models, Animal; Fructose; Gastrointestinal Motility; Male; Metabolic Diseases; Muscle, Smooth; Rats; Rats, Wistar; Retrospective Studies; Vasoconstrictor Agents; Water | 2020 |
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Topics: Angiotensin II; Animals; Biomarkers; Cells, Cultured; Disease Models, Animal; Disease Susceptibility; Epithelial Cells; Fibrosis; Forkhead Box Protein M1; Gene Expression Regulation; Humans; Immunohistochemistry; Kidney Diseases; Kidney Tubules; Male; Mice; Wnt Proteins; Wnt Signaling Pathway | 2021 |
Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apoe
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Chemokine CCL2; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Monocytes; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolines | 2022 |
Two-hit mechanism of cardiac arrhythmias in diabetic hyperglycaemia: reduced repolarization reserve, neurohormonal stimulation, and heart failure exacerbate susceptibility.
Topics: Action Potentials; Angiotensin II; Animals; Arrhythmias, Cardiac; Blood Glucose; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Diabetes Mellitus; Disease Models, Animal; Heart Conduction System; Heart Failure; Heart Rate; Isoproterenol; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Potassium Channels; Rabbits; Ryanodine Receptor Calcium Release Channel | 2021 |
Chronic Naltrexone Therapy Is Associated with Improved Cardiac Function in Volume Overloaded Rats.
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart Function Tests; Myocytes, Cardiac; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, Opioid; Treatment Outcome; Ventricular Dysfunction, Left; Water Intoxication | 2021 |
Piperlongumine attenuates angiotensin-II-induced cardiac hypertrophy and fibrosis by inhibiting Akt-FoxO1 signalling.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cardiomyopathies; Dioxolanes; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Failure; Kruppel-Like Factor 4; Myocytes, Cardiac; Nerve Tissue Proteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction | 2021 |
Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway.
Topics: ADAM10 Protein; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Calcium Chloride; Cell Movement; Chromones; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Morpholines; Neuropeptides; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Hormones; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Notch1; Transcription Factor HES-1 | 2021 |
Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Aortic Rupture; Aortography; Computed Tomography Angiography; Contrast Media; Diet, High-Fat; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Early Diagnosis; Male; Mice, Inbred C57BL; Nanoparticles; Predictive Value of Tests; Time Factors; Triiodobenzoic Acids; X-Ray Microtomography | 2021 |
Inhibition of plasma kallikrein mitigates experimental hypertension-enhanced cerebral hematoma expansion.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Hemorrhage; Crotalid Venoms; Disease Models, Animal; Hypertension; Lectins, C-Type; Male; Mice; Plasma Kallikrein; Treatment Outcome | 2021 |
Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress.
Topics: Angiotensin II; Animals; Antioxidants; Biomarkers; Biopsy; Blood Pressure; Cardiomegaly; Collagen; Coumarins; Disease Management; Disease Models, Animal; Disease Susceptibility; Echocardiography; Fibroblasts; Immunohistochemistry; Male; Mice; Myocytes, Cardiac; Oxidative Stress; Rats | 2021 |
Angiotensin II receptor 1 controls profibrotic Wnt/β-catenin signalling in experimental autoimmune myocarditis.
Topics: Angiotensin II; Animals; Autoimmune Diseases; Autoimmunity; beta Catenin; CD4-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Fibrosis; Inflammation Mediators; Lymphocyte Activation; Mice, Inbred BALB C; Mice, Knockout; Myocarditis; Myocytes, Cardiac; Receptor, Angiotensin, Type 1; Wnt Proteins; Wnt Signaling Pathway; Wnt1 Protein | 2022 |
Inhibition of CXCR2 alleviates the development of abdominal aortic aneurysm in Apo E-/- mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Macrophages; Mice; Mice, Inbred C57BL; Receptors, Interleukin-8B | 2021 |
PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Humans; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Rats, Sprague-Dawley; Sirtuin 2; Transcription Factors; Ventricular Remodeling | 2021 |
Proximal Tubule-Specific Deletion of Angiotensin II Type 1a Receptors in the Kidney Attenuates Circulating and Intratubular Angiotensin II-Induced Hypertension in PT-
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Knockout Techniques; Glomerular Filtration Rate; Hypertension; Kidney Tubules, Proximal; Mice; Natriuresis; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Hydrogen Exchanger 3 | 2021 |
MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Trans-Activators | 2021 |
Divergent impact of gestational diabetes mellitus between the thoracic and abdominal rat aorta: Influence of endothelium and angiotensin II receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Aorta, Thoracic; Diabetes, Gestational; Disease Models, Animal; Endothelium, Vascular; Female; Pregnancy; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2021 |
Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Arterial Pressure; Captopril; Disease Models, Animal; Kidney; Liver; Losartan; Rats; Renal Insufficiency, Chronic; Renin-Angiotensin System; RNA, Small Interfering | 2021 |
High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons.
Topics: Angiotensin II; Animals; Cell Membrane; Cytoskeleton; Disease Models, Animal; Excitatory Postsynaptic Potentials; Hypertension; Male; Mechanotransduction, Cellular; Neurons; Osmosis; Probability; Rats, Wistar; Sodium Chloride, Dietary; Synapses; Vasopressins | 2021 |
MicroRNA-212-5p and its target PAFAH1B2 suppress vascular proliferation and contraction via the downregulation of RhoA.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Angiotensin II; Animals; Antagomirs; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclin D1; Disease Models, Animal; Down-Regulation; Hypertension; MicroRNAs; Muscle Contraction; Muscle, Smooth, Vascular; Rats; rhoA GTP-Binding Protein; RNA Interference; RNA, Small Interfering; Vascular Remodeling | 2021 |
Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice.
Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Calpain; Cells, Cultured; Cytoskeleton; Dilatation, Pathologic; Disease Models, Animal; Extracellular Matrix; Female; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Rats; Receptors, LDL; Vascular Remodeling | 2021 |
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Histone Demethylases; Inflammation; Inflammation Mediators; Jumonji Domain-Containing Histone Demethylases; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Up-Regulation | 2021 |
CRIP1 expression in monocytes related to hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Cell Differentiation; Cohort Studies; Disease Models, Animal; Humans; Hypertension; Macrophages; Male; Monocytes; NG-Nitroarginine Methyl Ester; Spleen; Transcriptome | 2021 |
Cardiac Oxidative Signaling and Physiological Hypertrophy in the Na/K-ATPase α1
Topics: Angiotensin II; Animals; Cardiac Glycosides; Cardiomegaly; Disease Models, Animal; Echocardiography; Heart; Male; Mice; Mutation; Myocardium; Ouabain; Protein Isoforms; Reactive Oxygen Species; RNA-Seq; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2021 |
Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin.
Topics: Angiotensin II; Animals; Antifibrotic Agents; Cardiomegaly; Cell Survival; Disease Models, Animal; Extracellular Matrix; Fibrosis; Gene Expression; Heart Failure; Humans; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Myofibroblasts; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Pyrans; rho-Associated Kinases; Ventricular Remodeling | 2021 |
Effects of Endogenous Angiotensin II on Abdominal Aortic Aneurysms and Atherosclerosis in Angiotensin II-Infused Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Disease Models, Animal; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Vasoconstrictor Agents | 2021 |
Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Kidney Diseases; Male; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Prorenin Receptor; Proton-Translocating ATPases; Receptors, Cell Surface; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation; Water-Electrolyte Balance | 2021 |
Computed tomography imaging of macrophage phagocytic activity in abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Macrophages; Male; Mice; Mice, Inbred C57BL; Phagocytes; Tomography, X-Ray Computed | 2021 |
Adventitial recruitment of Lyve-1- macrophages drives aortic aneurysm in an angiotensin-2-based murine model.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Inflammation Mediators; Macrophages; Membrane Transport Proteins; Mice; Signal Transduction | 2021 |
Developmental and lifelong dioxin exposure induces measurable changes in cardiac structure and function in adulthood.
Topics: Angiotensin II; Animals; Basic Helix-Loop-Helix Transcription Factors; Dioxins; Disease Models, Animal; Embryonic Development; Environmental Pollutants; Female; Heart; Heart Defects, Congenital; Humans; Hypertrophy; Male; Mice; Physical Conditioning, Animal; Pilot Projects; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Renin-Angiotensin System; Sex Characteristics | 2021 |
Senolytic agents lessen the severity of abdominal aortic aneurysm in aged mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout | 2021 |
Omentin attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice.
Topics: Adipokines; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cytokines; Disease Models, Animal; GPI-Linked Proteins; Lectins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins c-akt | 2022 |
CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice.
Topics: ADP-ribosyl Cyclase 1; Angiotensin II; Animals; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Extracellular Vesicles; Humans; Hypertension; Membrane Glycoproteins; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Signal Transduction; Vascular Remodeling | 2021 |
Dapagliflozin: a sodium-glucose cotransporter 2 inhibitor, attenuates angiotensin II-induced cardiac fibrotic remodeling by regulating TGFβ1/Smad signaling.
Topics: Angiotensin II; Animals; Antifibrotic Agents; Benzhydryl Compounds; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Glucosides; Hypertrophy, Left Ventricular; Male; Myocardium; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Sodium-Glucose Transporter 2 Inhibitors; Transforming Growth Factor beta1; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2021 |
MicroRNA-17-5p Promotes Cardiac Hypertrophy by Targeting Mfn2 to Inhibit Autophagy.
Topics: Angiotensin II; Animals; Autophagy; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; GTP Phosphohydrolases; Male; MicroRNAs; Mitochondrial Proteins; Myocytes, Cardiac; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases | 2021 |
Losartan Protects Podocytes against High Glucose-induced Injury by Inhibiting B7-1 Expression.
Topics: Angiotensin II; Animals; Apoptosis; B7-1 Antigen; Class I Phosphatidylinositol 3-Kinases; Diabetic Nephropathies; Disease Models, Animal; Glucose; Humans; Kidney; Losartan; Mice; Podocytes; Rats; Receptor, Angiotensin, Type 1; Streptozocin | 2021 |
Inactivation of Interleukin-4 Receptor α Signaling in Myeloid Cells Protects Mice From Angiotensin II/High Salt-Induced Cardiovascular Dysfunction Through Suppression of Fibrotic Remodeling.
Topics: Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Hypertension; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; Myocardium; Receptors, Cell Surface; Signal Transduction; Sodium Chloride, Dietary; Ventricular Remodeling | 2021 |
Megalin-mediated albumin endocytosis in renal proximal tubules is involved in the antiproteinuric effect of angiotensin II type 1 receptor blocker in a subclinical acute kidney injury animal model.
Topics: Acute Kidney Injury; Albumins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Disease Models, Animal; Endocytosis; Kidney Tubules, Proximal; Losartan; Low Density Lipoprotein Receptor-Related Protein-2; Male; Mice; Mice, Inbred C57BL | 2021 |
Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1/NF-κB pathway.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Cells, Cultured; Disease Models, Animal; Fibrosis; Ginsenosides; Humans; Hypertrophy; Immunomodulation; Inflammasomes; Myocardium; Myocytes, Cardiac; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Rats; Signal Transduction; Sirtuin 1 | 2021 |
Sirtuin 3 deficiency aggravates angiotensin II-induced hypertensive cardiac injury by the impairment of lymphangiogenesis.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Heart Injuries; Hypertension; Lymphangiogenesis; Male; Mice; Mice, Knockout; Sirtuin 3; Vascular Endothelial Growth Factor Receptor-3; Vasoconstrictor Agents | 2021 |
Artesunate Attenuated the Progression of Abdominal Aortic Aneurysm in a Mouse Model.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Artesunate; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL | 2021 |
IGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting αSMA.
Topics: Actins; Angiotensin II; Animals; Cardiomyopathies; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Infusions, Intravenous; Insulin-Like Growth Factor I; Male; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phenylephrine; Proto-Oncogene Proteins c-akt; Rats; Receptor, IGF Type 1; rho-Associated Kinases; Signal Transduction | 2021 |
Sex differences in angiotensin II-induced hypertension and kidney injury: role of AT1a receptors in the proximal tubule of the kidney.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterial Pressure; Disease Models, Animal; Female; Fibrosis; Hypertension; Kidney Diseases; Kidney Tubules, Proximal; Losartan; Male; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sex Characteristics; Sex Factors; Signal Transduction | 2021 |
Expression and role of lumican in acute aortic dissection: A human and mouse study.
Topics: Acute Disease; Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Dissection; Aortic Rupture; Biomarkers; Chronic Disease; Disease Models, Animal; Humans; Incidence; Kaplan-Meier Estimate; Lumican; Mice; Mice, Inbred C57BL; Mice, Knockout; Smad2 Protein; Transforming Growth Factor beta; Up-Regulation | 2021 |
The variations of endophilin A2-FoxO3a-autophagy signal in angiotensin II-induced dopaminergic neuron injury mouse model and by biochanin A.
Topics: Acyltransferases; Angiotensin II; Animals; Autophagy; Disease Models, Animal; Dopaminergic Neurons; Forkhead Box Protein O3; Gene Expression; Gene Expression Regulation; Genistein; Male; Mice, Inbred C57BL; Signal Transduction | 2021 |
Krüppel-Like Factor 15/Interleukin 11 Axis-Mediated Adventitial Remodeling Depends on Extracellular Signal-Regulated Kinases 1 and 2 Activation in Angiotensin II-Induced Hypertension.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Thoracic; Disease Models, Animal; Fibroblasts; Fibrosis; HEK293 Cells; Humans; Hypertension; Inflammation Mediators; Interleukin-11; Kruppel-Like Transcription Factors; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2021 |
Glucagon-like peptide-1 attenuates cardiac hypertrophy via the AngII/AT1R/ACE2 and AMPK/mTOR/p70S6K pathways.
Topics: Adenylate Kinase; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomegaly; Cardiotonic Agents; Cell Line; Disease Models, Animal; Glucagon-Like Peptide 1; Hypertension; Liraglutide; Male; Morpholines; Myocytes, Cardiac; Piperidines; Rats; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Triazines; Uracil | 2021 |
MiR-26a-5p alleviates cardiac hypertrophy and dysfunction via targeting ADAM17.
Topics: ADAM17 Protein; Angiotensin II; Animals; Autophagy; Cardiomegaly; Cell Line; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Myocytes, Cardiac; Signal Transduction | 2021 |
Angiotensin II promotes primary tumor growth and metastasis formation of murine TNBC 4T1 cells through the fibroblasts around cancer cells.
Topics: Angiotensin II; Animals; Cancer-Associated Fibroblasts; Cell Line, Tumor; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Humans; Lung; Lung Neoplasms; Mammary Glands, Animal; Mice; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2021 |
Resolvin-D1 attenuation of angiotensin II-induced cardiac inflammation in mice is associated with prevention of cardiac remodeling and hypertension.
Topics: Angiotensin II; Animals; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Docosahexaenoic Acids; Gene Expression Regulation; Humans; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Mice; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Ventricular Remodeling | 2021 |
Vitamin D suppresses bleomycin-induced pulmonary fibrosis by targeting the local renin-angiotensin system in the lung.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Bleomycin; Disease Models, Animal; Ergocalciferols; Losartan; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Transforming Growth Factor beta; Vitamin D | 2021 |
Allosteric activation of PP2A inhibits experimental abdominal aortic aneurysm.
Topics: Allosteric Regulation; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Case-Control Studies; Dilatation, Pathologic; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Extracellular Signal-Regulated MAP Kinases; Humans; Macrophages; Male; Mice; Mice, Knockout, ApoE; NF-kappa B; Protein Phosphatase 2; RAW 264.7 Cells; Vascular Remodeling | 2021 |
Blocking of interleukin-1 suppresses angiotensin II-induced renal injury.
Topics: Angiotensin II; Animals; Antibodies; Blood Pressure; Bosentan; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Fibrosis; Humans; Hypertension; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction | 2021 |
MiR-590-5p inhibits pathological hypertrophy mediated heart failure by targeting RTN4.
Topics: Angiotensin II; Animals; Apoptosis; Base Sequence; Biomarkers; Cardiomegaly; Cell Line; Disease Models, Animal; Down-Regulation; Heart Failure; Mice, Inbred C57BL; MicroRNAs; Nogo Proteins; Protein Binding | 2021 |
rAAV9-mediated supplementation of miR-29b improve angiotensin-II induced renal fibrosis in mice.
Topics: Angiotensin II; Animals; Cell Line; Dependovirus; Disease Models, Animal; Fibrosis; Gene Expression; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Immunohistochemistry; Kidney Diseases; Male; Mice; MicroRNAs; Transduction, Genetic | 2021 |
Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Fibrosis; Genomics; Humans; Mice; Mice, Inbred C57BL; Pancreatic Elastase; Swine | 2021 |
Thrombin Inhibition Prevents Endothelial Dysfunction and Reverses 20-HETE Overproduction without Affecting Blood Pressure in Angiotensin II-Induced Hypertension in Mice.
Topics: Angiotensin II; Animals; Antithrombins; Chromatography, Liquid; Dabigatran; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Hypertension; Intercellular Adhesion Molecule-1; Male; Mice; Nitric Oxide; Tandem Mass Spectrometry; Vascular Remodeling; von Willebrand Factor | 2021 |
Vinpocetine Attenuates Pathological Cardiac Remodeling by Inhibiting Cardiac Hypertrophy and Fibrosis.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiomyopathies; Cell Proliferation; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 1; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Phosphodiesterase Inhibitors; Signal Transduction; Ventricular Remodeling; Vinca Alkaloids | 2017 |
Angiotensin II induces kidney inflammatory injury and fibrosis through binding to myeloid differentiation protein-2 (MD2).
Topics: Angiotensin II; Animals; Biopsy; Cytokines; Disease Models, Animal; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Inflammation Mediators; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Lymphocyte Antigen 96; Mice; Mice, Knockout; NF-kappa B; Protein Binding; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Angiotensin II promotes the anticoagulant effects of rivaroxaban via angiotensin type 2 receptor signaling in mice.
Topics: Angiotensin II; Animals; Cells, Cultured; Cytokines; Diabetes Mellitus, Type 2; Disease Models, Animal; Factor Xa Inhibitors; Glycation End Products, Advanced; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Mice, Inbred C57BL; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Rivaroxaban; Signal Transduction | 2017 |
Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress.
Topics: Angiotensin II; Animals; Antibodies; Brain Ischemia; Disease Models, Animal; Immunotherapy, Active; Infarction, Middle Cerebral Artery; Male; Oxidative Stress; Rats; Rats, Wistar; Renin-Angiotensin System; Stroke; Vaccines, Subunit | 2017 |
High serum thrombospondin-1 concentration is associated with slower abdominal aortic aneurysm growth and deficiency of thrombospondin-1 promotes angiotensin II induced aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Cells, Cultured; Collagen Type III; Disease Models, Animal; Disease Progression; Elastin; Genetic Predisposition to Disease; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Male; Matrix Metalloproteinase 9; Mice, Knockout; Odds Ratio; Phenotype; Proteolysis; Receptors, LDL; Risk Factors; Thrombospondin 1; Time Factors; Tumor Suppressor Proteins; Ultrasonography; Vascular Remodeling | 2017 |
Inhibition of endoplasmic reticulum stress signaling pathway: A new mechanism of statins to suppress the development of abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Atorvastatin; Calcium Chloride; Cell Line; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Random Allocation | 2017 |
ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.
Topics: Angiotensin II; Animals; Aorta; Apelin Receptors; Arterial Pressure; Cardiotonic Agents; Constriction; Disease Models, Animal; Fibrosis; Forkhead Box Protein M1; Gene Expression Regulation; Heart Failure; HEK293 Cells; Humans; Hypertension; Hypertrophy, Left Ventricular; Infusions, Subcutaneous; Ligands; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardium; Peptide Hormones; Peptidyl-Dipeptidase A; Signal Transduction; Transfection; Ventricular Dysfunction, Left; Ventricular Function, Left | 2017 |
Critical Role of ADAMTS2 (A Disintegrin and Metalloproteinase With Thrombospondin Motifs 2) in Cardiac Hypertrophy Induced by Pressure Overload.
Topics: ADAMTS Proteins; Angiotensin II; Animals; Biopsy, Needle; Cardiomegaly; Disease Models, Animal; Disintegrins; Gene Expression Regulation; Humans; Metalloproteases; Mice; Mice, Transgenic; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Random Allocation; Signal Transduction; Thrombospondins; Tissue Culture Techniques; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Remodeling | 2017 |
Intracellular Angiotensin-II Interacts With Nuclear Angiotensin Receptors in Cardiac Fibroblasts and Regulates RNA Synthesis, Cell Proliferation, and Collagen Secretion.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Calcium; Cell Nucleus; Cell Proliferation; Collagen; Collagen Type I; Disease Models, Animal; Dogs; Fibroblasts; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein beta Subunits; Heart Atria; Heart Failure; Immunoblotting; Inositol 1,4,5-Trisphosphate Receptors; Microscopy, Fluorescence; Nitric Oxide; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Transcription, Genetic | 2017 |
Brain Renin-Angiotensin System: Does It Exist?
Topics: Amides; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Desoxycorticosterone Acetate; Disease Models, Animal; Fumarates; Hypertension; Mice; Mice, Knockout; Random Allocation; Rats; Rats, Inbred SHR; Reference Values; Renin-Angiotensin System | 2017 |
Resistance to hypertension mediated by intercalated cells of the collecting duct.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Hypertension; Kidney Tubules, Collecting; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1 | 2017 |
2-Methoxyestradiol Reduces Angiotensin II-Induced Hypertension and Renal Dysfunction in Ovariectomized Female and Intact Male Mice.
Topics: 2-Methoxyestradiol; Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Cytochrome P-450 CYP1B1; Disease Models, Animal; Estradiol; Female; Hypertension; Kidney Diseases; Kidney Function Tests; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovariectomy; Random Allocation; Reactive Oxygen Species; Sensitivity and Specificity; Sex Factors | 2017 |
Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Angiotensin II; Animals; Behavior, Animal; Blood Pressure; Brain; Cognition; Disease Models, Animal; Hippocampus; Inflammation; Infusions, Intraventricular; Male; Mice; Mice, Transgenic; Muscle, Skeletal; Muscular Atrophy; Oxidative Stress; Sarcopenia; Vasoconstrictor Agents | 2017 |
β-Aminoisobutyric acid ameliorates the renal fibrosis in mouse obstructed kidneys via inhibition of renal fibroblast activation and fibrosis.
Topics: Aminoisobutyric Acids; Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Fibrosis; Interleukin-17; Kidney; Male; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Insufficiency, Chronic; Signal Transduction | 2017 |
The NRF2 activator DH404 attenuates adverse ventricular remodeling post-myocardial infarction by modifying redox signalling.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cells, Cultured; Disease Models, Animal; Fibronectins; Glutaredoxins; Heart; Humans; Male; Myocardial Infarction; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Oleanolic Acid; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Ventricular Remodeling | 2017 |
Crucial Role of ROCK2-Mediated Phosphorylation and Upregulation of FHOD3 in the Pathogenesis of Angiotensin II-Induced Cardiac Hypertrophy.
Topics: Amides; Analysis of Variance; Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Formins; Male; Microfilament Proteins; Myocytes, Cardiac; Phosphorylation; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; rho-Associated Kinases; Signal Transduction; Up-Regulation | 2017 |
Azilsartan ameliorates apoptosis of dopaminergic neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinson's disease.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Behavior, Animal; Benzimidazoles; Disease Models, Animal; Dopaminergic Neurons; Humans; Male; Oxadiazoles; Parkinson Disease; Rats; Receptor, Angiotensin, Type 1; Substantia Nigra | 2017 |
Pressure-overload-induced angiotensin-mediated early remodeling in mouse heart.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Disease Models, Animal; Heart Diseases; Hypertrophy; Membrane Potentials; Mice, Inbred C57BL; Myocytes, Cardiac; Patch-Clamp Techniques; Pressure; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Saralasin; Stress, Physiological | 2017 |
SIRT3-KLF15 signaling ameliorates kidney injury induced by hypertension.
Topics: Acetylation; Angiotensin II; Animals; Biphenyl Compounds; Disease Models, Animal; Fibrosis; Gene Expression; Gene Expression Regulation; Hypertension, Renal; Kidney; Kruppel-Like Transcription Factors; Lignans; Mice; Mice, Knockout; Models, Biological; Nephritis; Nuclear Proteins; Podocytes; Protein Binding; Signal Transduction; Sirtuin 3 | 2017 |
Micturition dysfunction in four-month old ovariectomized rats: Effects of testosterone replacement.
Topics: Acetanilides; Androgens; Angiotensin II; Animals; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Letrozole; Muscle, Smooth; Nitriles; Ovariectomy; Postmenopause; Rats; Rats, Sprague-Dawley; Testosterone; Thiazoles; Triazoles; Urethra; Urination Disorders | 2017 |
Colchicine attenuates renal fibrosis in a murine unilateral ureteral obstruction model.
Topics: Angiotensin II; Animals; Biomarkers; Cell Line; Cell Movement; Cell Survival; Colchicine; Disease Models, Animal; Fibroblasts; Fibrosis; Immunohistochemistry; Kidney Diseases; Male; Mice; Rats; rhoA GTP-Binding Protein; Ureteral Obstruction | 2017 |
Use of a Fluorescent Substrate to Measure ACE2 Activity in the Mouse Abdominal Aorta.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Disease Models, Animal; Fluorescent Antibody Technique; Fluorescent Dyes; Hyperlipidemias; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Receptors, LDL; Sodium Chloride; Vasoconstrictor Agents | 2017 |
Recombinant adeno-associated virus vector carrying the thrombomodulin lectin-like domain for the treatment of abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Cytokines; Dependovirus; Disease Models, Animal; Elastin; Genetic Therapy; Genetic Vectors; HMGB1 Protein; Macrophages; Male; Matrix Metalloproteinases; Mice, Knockout, ApoE; Oxidative Stress; Protein Domains; Receptor for Advanced Glycation End Products; Thrombomodulin; Vascular Remodeling | 2017 |
Adipose angiotensin II type 1 receptor-associated protein ameliorates metabolic disorders via promoting adipose tissue adipogenesis and browning.
Topics: Adaptor Proteins, Signal Transducing; Adipocytes; Adipogenesis; Adipokines; Adipose Tissue; Angiotensin II; Animals; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation; Humans; Insulin; Metabolic Diseases; Mice; Mice, Transgenic | 2017 |
Chronic administration of sodium nitrite prevents hypertension and protects arterial endothelial function by reducing oxidative stress in angiotensin II-infused mice.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta, Thoracic; Arterial Pressure; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidase 4; Nitric Oxide; Oxidative Stress; Renal Artery; Sodium Nitrite; Tyrosine; Vasodilation | 2018 |
Gingival fibroblasts protect against experimental abdominal aortic aneurysm development and rupture through tissue inhibitor of metalloproteinase-1 production.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Gingiva; Mice, Inbred C57BL; Mice, Knockout; Protective Agents; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta | 2017 |
Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis.
Topics: Actins; Angiotensin II; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cells, Cultured; Connective Tissue Growth Factor; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Scleroderma, Systemic; Skin | 2017 |
The loss of Krüppel-like factor 15 in Foxd1
Topics: Angiotensin II; Animals; beta Catenin; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Disease Progression; DNA-Binding Proteins; Fibrosis; Forkhead Transcription Factors; Gene Expression Regulation; Gene Knockdown Techniques; Kidney; Kidney Diseases; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Myofibroblasts; Phosphorylation; RNA, Messenger; Stromal Cells; Transcription Factors; Wnt Signaling Pathway; Wnt1 Protein | 2017 |
2K1C-activated Angiotensin II (Ang II) exacerbates vascular damage in a rat model of arthritis through the ATR/ERK1/2 signaling pathway.
Topics: Angiotensin II; Animals; Arthritis; Ataxia Telangiectasia Mutated Proteins; Blood Pressure; Blood Vessels; Capillary Tubing; Cell Movement; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Hypertension, Renovascular; Male; MAP Kinase Signaling System; NF-kappa B; Rats; Rats, Sprague-Dawley | 2017 |
Tail-Cuff Technique and Its Influence on Central Blood Pressure in the Mouse.
Topics: Angiotensin II; Animals; Behavior, Animal; Blood Pressure; Blood Pressure Determination; Body Temperature Regulation; Disease Models, Animal; Female; Habituation, Psychophysiologic; Handling, Psychological; Heart Rate; Humans; Hypertension; Male; Mice, Inbred C57BL; Plethysmography; Predictive Value of Tests; Regional Blood Flow; Reproducibility of Results; Restraint, Physical; Stress, Psychological; Tail; Telemetry; Time Factors | 2017 |
Vaccarin administration ameliorates hypertension and cardiovascular remodeling in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Flavonoids; Gene Expression Regulation; Glycosides; Hypertension; Male; Norepinephrine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin; Ventricular Remodeling | 2018 |
STAT3 balances myocyte hypertrophy vis-à-vis autophagy in response to Angiotensin II by modulating the AMPKα/mTOR axis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Angiotensin II; Animals; Autophagy; Disease Models, Animal; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Hypertrophy; Myocytes, Cardiac; Pyridines; Rats; Signal Transduction; STAT3 Transcription Factor; TOR Serine-Threonine Kinases; Tyrphostins | 2017 |
Phospholipase Cγ1 Mediates Intima Formation Through Akt-Notch1 Signaling Independent of the Phospholipase Activity.
Topics: Angiotensin II; Animals; Apoptosis; Carotid Artery Injuries; Cell Dedifferentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Phospholipase C gamma; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Rats; Receptor, Notch1; RNA Interference; Signal Transduction; Time Factors; Transfection; Vascular Remodeling | 2017 |
Melatonin protects against the pathological cardiac hypertrophy induced by transverse aortic constriction through activating PGC-1β: In vivo and in vitro studies.
Topics: Angiotensin II; Animals; Antioxidants; Cardiomegaly; Disease Models, Animal; Drug Evaluation, Preclinical; Fibrosis; Heart; Lung Diseases; Male; Melatonin; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Primary Cell Culture; Transcriptional Activation | 2017 |
Angiotensin II responsiveness after preeclampsia: translational data from an experimental rat model and early-onset human preeclampsia.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Female; Humans; Kidney; Postpartum Period; Pre-Eclampsia; Pregnancy; Rats | 2017 |
Role of the histone deacetylase inhibitor valproic acid in high-fat diet-induced hypertension via inhibition of HDAC1/angiotensin II axis.
Topics: Angiotensin II; Animals; Blotting, Western; Diet, High-Fat; Disease Models, Animal; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Hypertension; Male; Mice; Mice, Inbred C57BL; Valproic Acid | 2017 |
TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms.
Topics: Adventitia; Angiotensin II; Animals; Antibodies; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Phenotype; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Severity of Illness Index; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Transforming Growth Factor beta3; Tunica Media; Vascular Remodeling | 2017 |
Nitroxyl Anion Mediates Relaxation in Mesenteric Arteries from Angiotensin II Hypertensive Mice.
Topics: 4-Aminopyridine; Acetylcholine; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; Nitrogen Oxides; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2017 |
Effect of uric acid on inflammatory COX-2 and ROS pathways in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Disease Models, Animal; Humans; Hypertension; Inflammation; Losartan; Muscle, Smooth, Vascular; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; Receptor Protein-Tyrosine Kinases; Signal Transduction; Superoxides; Uric Acid | 2017 |
Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Atherosclerosis; Disease Models, Animal; Heparin-binding EGF-like Growth Factor; Hyperlipidemias; Liver; Male; Mice; Receptors, LDL | 2017 |
Primary Cilia Deficiency Induces Intracranial Aneurysm.
Topics: Angiotensin II; Animals; Cells, Cultured; Cilia; Disease Models, Animal; Humans; Intracranial Aneurysm; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; TRPP Cation Channels | 2018 |
Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Epithelial Sodium Channels; Genetic Predisposition to Disease; Hypertension; Kidney Tubules, Collecting; Mice, Inbred C57BL; Mice, Knockout; Natriuresis; Phenotype; Proteinuria; Proton-Translocating ATPases; Receptors, Cell Surface; Renal Elimination; Renin; Sodium; Sodium Chloride, Dietary; Time Factors | 2017 |
Adaptive responses of rat descending vasa recta to ischemia.
Topics: Adaptation, Physiological; Amidines; Angiotensin II; Animals; Arterioles; Benzylamines; Constriction; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Humans; Ischemia; Kidney; Membrane Potentials; Nitric Oxide; Nitric Oxide Synthase Type II; Pericytes; Rats, Sprague-Dawley; Renal Artery; Renal Circulation; Vasoconstriction; Vasoconstrictor Agents | 2018 |
Evidence for Prohypertensive, Proinflammatory Effect of Interleukin-10 During Chronic High Salt Intake in the Condition of Elevated Angiotensin II Level.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Interleukin-10; Kidney; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Sodium Chloride, Dietary | 2017 |
Ultraviolet B Exposure Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice by Expanding CD4
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Cell Proliferation; Cholesterol, Dietary; Disease Models, Animal; Forkhead Transcription Factors; Lymph Nodes; Lymphocyte Activation; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phenotype; T-Lymphocytes, Regulatory; Time Factors; Ultraviolet Therapy | 2017 |
A Systems Biology Approach to Investigating Sex Differences in Cardiac Hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Female; Gene Expression Regulation; Gene Regulatory Networks; Male; Mice, Inbred C57BL; MicroRNAs; Myocardium; Oxazoles; PPAR alpha; Protein Interaction Maps; RNA, Messenger; Sex Characteristics; Sex Factors; Signal Transduction; Systems Biology; Time Factors; Tyrosine | 2017 |
Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis.
Topics: Acetylation; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Collagen Type I; Collagen Type III; Disease Models, Animal; Disease Progression; Fibrosis; Genetic Predisposition to Disease; Hypertension; Mice, 129 Strain; Mice, Knockout; Mitochondria, Heart; Mitophagy; Myocardium; Neovascularization, Physiologic; Oxidative Stress; Phenotype; Protein Kinases; Signal Transduction; Sirtuin 3; Time Factors; Tissue Culture Techniques; Ubiquitin-Protein Ligases; Ventricular Remodeling | 2017 |
Acute simvastatin treatment restores cerebral functional capillary density and attenuates angiotensin II-induced microcirculatory changes in a model of primary hypertension.
Topics: Angiotensin II; Animals; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Male; Microcirculation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Simvastatin | 2017 |
Angiotensin II induces cholesterol accumulation and injury in podocytes.
Topics: Angiotensin II; Animals; Apoptosis; Cholesterol; Cytoskeleton; Disease Models, Animal; Gene Expression; Lipid Metabolism; Perilipin-2; Podocytes; Renal Insufficiency, Chronic; Simvastatin | 2017 |
Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Apolipoproteins E; Bone Marrow Transplantation; Calcium Chloride; Cell Line; Chemokine CCL2; Cholesterol, HDL; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Humans; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phenotype; Signal Transduction; Time Factors; Transfection; Vascular Remodeling | 2017 |
MAPK activation patterns of AT1R and CB1R in SHR versus Wistar astrocytes: Evidence of CB1R hypofunction and crosstalk between AT1R and CB1R.
Topics: Angiotensin II; Animals; Arachidonic Acids; Astrocytes; Blood Pressure; Cannabinoids; Disease Models, Animal; Humans; Hypertension; MAP Kinase Kinase 1; Phosphorylation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, Cannabinoid | 2017 |
Angiotensin II infusion into ApoE-/- mice: a model for aortic dissection rather than abdominal aortic aneurysm?
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortography; Computed Tomography Angiography; Disease Models, Animal; Disease Progression; Hematoma; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Time Factors; Ultrasonography, Doppler, Pulsed; Vascular Remodeling; X-Ray Microtomography | 2017 |
Treatment of hypertension by increasing impaired endothelial TRPV4-KCa2.3 interaction.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Fluorescence; Mutagenesis; Nitroprusside; Plasmids; Potassium Channels, Calcium-Activated; TRPV Cation Channels; Vasodilation | 2017 |
Stimulation of ganglionated plexus attenuates cardiac neural remodeling and heart failure progression in a canine model of acute heart failure post-myocardial infarction.
Topics: Angiotensin II; Animals; Biomarkers; Disease Models, Animal; Disease Progression; Dogs; Electric Stimulation Therapy; GAP-43 Protein; Heart; Heart Failure; Male; Myocardial Infarction; Natriuretic Peptide, Brain; Nerve Growth Factor; Norepinephrine; Parasympathetic Nervous System; Proto-Oncogene Proteins c-fos; Random Allocation; Tyrosine 3-Monooxygenase | 2017 |
Icariin improves acute kidney injury and proteinuria in a rat model of pregnancy‑induced hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Down-Regulation; Female; Flavonoids; Gestational Age; Hypertension, Pregnancy-Induced; Kidney; Membrane Proteins; NG-Nitroarginine Methyl Ester; Pregnancy; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System; Reproduction; Up-Regulation | 2017 |
Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice.
Topics: ADAMTS4 Protein; Aged; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Thoracic; Aortic Dissection; Apoptosis; Diet, High-Fat; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myocytes, Smooth Muscle; Proteolysis; Versicans | 2017 |
Effects of early overnutrition on the renal response to Ang II and expression of RAAS components in rat renal tissue.
Topics: Adipose Tissue; Age Factors; Angiotensin II; Animal Nutritional Physiological Phenomena; Animals; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Kidney; Nitric Oxide Synthase Type III; Nutritional Status; Overnutrition; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; Renin-Angiotensin System; RNA, Messenger; Tumor Necrosis Factor-alpha; Vasoconstriction; Vasoconstrictor Agents | 2017 |
Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine.
Topics: Angiotensin II; Animals; Antioxidants; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Disease Models, Animal; Gene Deletion; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Neutrophils; Oxidative Stress; Pancreatic Elastase; Peroxidase; Reactive Oxygen Species; Serum Amyloid A Protein; Taurine | 2017 |
Interleukin 22 Promotes Blood Pressure Elevation and Endothelial Dysfunction in Angiotensin II-Treated Mice.
Topics: Adult; Aged; Angiotensin II; Animals; Antibodies, Monoclonal; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation Mediators; Interleukin-22; Interleukins; Male; Mice, Inbred C57BL; Middle Aged; Nitric Oxide Synthase Type III; Phosphorylation; Recombinant Proteins; STAT3 Transcription Factor; Time Factors; Vasodilation; Vasodilator Agents | 2017 |
Apelin Is a Negative Regulator of Angiotensin II-Mediated Adverse Myocardial Remodeling and Dysfunction.
Topics: Angiotensin II; Animals; Animals, Newborn; Apelin; Apoptosis; Cells, Cultured; Disease Models, Animal; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Knockout; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Ventricular Remodeling | 2017 |
Endothelial Mineralocorticoid Receptor Mediates Parenchymal Arteriole and Posterior Cerebral Artery Remodeling During Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Hypertension; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Posterior Cerebral Artery; Receptors, Mineralocorticoid; Vascular Remodeling | 2017 |
Topics: Actins; Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Movement; Cells, Cultured; Disease Models, Animal; Genotype; Hypertension; Male; Mice; Mutation, Missense; Myosin Heavy Chains; Nephrectomy; Nonmuscle Myosin Type IIA; Podocytes; Primary Cell Culture; Renal Insufficiency, Chronic; Sodium Chloride, Dietary; Stress Fibers; Tetrazoles | 2018 |
Sex Differences in Vascular Reactivity to Angiotensin II During the Evolution of Myocardial Infarction.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Disease Models, Animal; Female; Male; Myocardial Infarction; Rats, Wistar; Receptor, Angiotensin, Type 1; Sex Factors; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2018 |
Sex differences in maternal gestational hypertension-induced sensitization of angiotensin II hypertension in rat offspring: the protective effect of estrogen.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression Regulation; Gestational Age; Hypertension; Hypertension, Pregnancy-Induced; Male; NADPH Oxidase 2; Orchiectomy; Ovariectomy; Pregnancy; Prenatal Exposure Delayed Effects; Protective Factors; Rats, Sprague-Dawley; Renin-Angiotensin System; Risk Factors; Sex Factors | 2018 |
New Mouse Model of Abdominal Aortic Aneurysm: Put Out to Expand.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice | 2017 |
Urinary Oxygenation as a Surrogate Measure of Medullary Oxygenation During Angiotensin II Therapy in Septic Acute Kidney Injury.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Biomarkers; Blood Pressure; Cytokines; Disease Models, Animal; Female; Hemodynamics; Kidney Function Tests; Kidney Medulla; Oxygen; Sepsis; Sheep | 2018 |
Sex Chromosome Complement Defines Diffuse Versus Focal Angiotensin II-Induced Aortic Pathology.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Phenotype; Receptors, LDL; Sex Characteristics; Sex Factors; Sex-Determining Region Y Protein; Testosterone; Vascular Remodeling; Vascular Stiffness; X Chromosome; Y Chromosome | 2018 |
Elevated Wall Tension Initiates Interleukin-6 Expression and Abdominal Aortic Dilation.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Arterial Pressure; CD11b Antigen; Cells, Cultured; Chemokine CCL2; Dilatation, Pathologic; Disease Models, Animal; Female; Interleukin-6; Macrophages; Male; Mechanotransduction, Cellular; Mice; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; STAT3 Transcription Factor; Stress, Mechanical | 2018 |
Inhibition of angiotensin II and calpain attenuates pleural fibrosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bleomycin; Calpain; Carbon; Cell Line; Collagen Type I; Dipeptides; Disease Models, Animal; Fibrosis; Humans; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pleural Diseases | 2018 |
Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.
Topics: Angiotensin II; Animals; Biomarkers; Blood Glucose; Blood Pressure; Cardiomegaly; Diet, High-Fat; Disease Models, Animal; Female; Fibrosis; Genetic Predisposition to Disease; Heart Rate; Hypertension; Male; Metabolic Syndrome; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NADPH Oxidase 4; Phenotype; Reactive Oxygen Species; Time Factors; Triglycerides; Ventricular Remodeling | 2018 |
MicroRNA-130a, a Potential Antifibrotic Target in Cardiac Fibrosis.
Topics: Angiotensin II; Animals; Blotting, Western; Cardiomyopathies; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Immunohistochemistry; Male; Mice; Mice, Transgenic; MicroRNAs; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; RNA; Up-Regulation | 2017 |
Central and peripheral slow-pressor mechanisms contributing to Angiotensin II-salt hypertension in rats.
Topics: Aldosterone; Angiotensin II; Animals; Arterial Pressure; Brain; Cardenolides; Cardiovascular System; Cytochrome P-450 CYP11B2; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Male; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Renin-Angiotensin System; Saponins; Sodium Chloride, Dietary; Sodium-Calcium Exchanger; Sympathetic Nervous System; Time Factors | 2018 |
Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis.
Topics: Angiotensin II; Animals; Atherosclerosis; Disease Models, Animal; Inflammation; Leukocytes; Mice; Mice, Knockout; Receptors, LDL; Rho Guanine Nucleotide Exchange Factors; Vasculitis | 2017 |
Identifications of potential therapeutic targets and drugs in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Gene Expression Profiling; Gene Ontology; Hypertension; Mice; MicroRNAs; Molecular Targeted Therapy | 2017 |
Time course of angiotensin II dependent vascular and metabolic effects of preeclampsia.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Female; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar | 2017 |
Recombinant Decorin Fusion Protein Attenuates Murine Abdominal Aortic Aneurysm Formation and Rupture.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Decorin; Disease Models, Animal; Humans; Mice; Mice, Knockout; Recombinant Proteins | 2017 |
Angiotensin II Infusion Does Not Cause Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Rats.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol; Disease Models, Animal; Gene Knockout Techniques; Genetic Predisposition to Disease; Phenotype; Rats, Sprague-Dawley; Rats, Transgenic; Time Factors; Ultrasonography, Doppler | 2018 |
Burst patterning of hypothalamic paraventricular nucleus-driven sympathetic nerve activity in ANG II-salt hypertension.
Topics: Angiotensin II; Animals; Arterial Pressure; Baroreflex; Disease Models, Animal; GABA-A Receptor Agonists; Heart; Heart Rate; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Periodicity; Phrenic Nerve; Rats, Sprague-Dawley; Respiratory Rate; Sodium Chloride, Dietary; Splanchnic Nerves; Sympathetic Nervous System; Time Factors | 2018 |
Upregulation of Cabin1 During Injury to Renal Tubular Epithelial Cells in Rats.
Topics: Angiotensin II; Animals; Apoptosis Regulatory Proteins; Cadherins; Cell Line; Disease Models, Animal; Epithelial Cells; Fibrosis; Kidney Diseases; Kidney Tubules; Mitochondria; Mitochondrial Swelling; Nephrectomy; Rats, Sprague-Dawley; Smad Proteins; Time Factors; Up-Regulation | 2017 |
A novel reproducible model of aortic aneurysm rupture.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Rupture; Cytokines; Disease Models, Animal; Male; Mice; Mice, Knockout, ApoE | 2018 |
DKK3 overexpression attenuates cardiac hypertrophy and fibrosis in an angiotensin-perfused animal model by regulating the ADAM17/ACE2 and GSK-3β/β-catenin pathways.
Topics: ADAM17 Protein; Adaptor Proteins, Signal Transducing; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Apoptosis; beta Catenin; Cardiomegaly; Cell Proliferation; Disease Models, Animal; Fibroblasts; Fibrosis; Glycogen Synthase Kinase 3 beta; Inflammation; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinases; Mice, Inbred C57BL; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Phosphorylation; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2018 |
Loss of Vascular Myogenic Tone in miR-143/145 Knockout Mice Is Associated With Hypertension-Induced Vascular Lesions in Small Mesenteric Arteries.
Topics: Actin Cytoskeleton; Angiotensin II; Animals; Arterial Pressure; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Elastic Tissue; Female; Fibrosis; Gene Knockout Techniques; Hyperplasia; Hypertension; Male; Mesenteric Arteries; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Neointima; Vascular Remodeling; Vascular Resistance; Vasoconstriction | 2018 |
Losartan suppresses the kainate-induced changes of angiotensin AT
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Blood Pressure; Comorbidity; Disease Models, Animal; Epilepsy; Gene Expression; Hippocampus; Hypertension; Kainic Acid; Limbic System; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2018 |
Cortistatin attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the ERK1/2 signaling pathways.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Cell Line; Disease Models, Animal; Elastin; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Myocytes, Smooth Muscle; Neuropeptides; Proteolysis; Reactive Oxygen Species | 2018 |
Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cadherins; Cell Proliferation; Disease Models, Animal; Humans; Male; Matrix Metalloproteinase 7; Mice; Mice, Inbred C57BL; Mice, Knockout; Severity of Illness Index; Signal Transduction | 2017 |
Cardiac and respiratory-gated volumetric murine ultrasound.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Biomechanical Phenomena; Cardiac-Gated Imaging Techniques; Disease Models, Animal; Echocardiography, Four-Dimensional; Heart Ventricles; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Myocardial Infarction; Predictive Value of Tests; Reproducibility of Results; Respiratory-Gated Imaging Techniques; Vascular Stiffness; Ventricular Function, Left | 2018 |
MiR-181a mediates Ang II-induced myocardial hypertrophy by mediating autophagy.
Topics: Adenine; Angiotensin II; Animals; Autophagy; Autophagy-Related Protein 5; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Down-Regulation; Male; MicroRNAs; Microtubule-Associated Proteins; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley | 2017 |
The novel organic mononitrate NDHP attenuates hypertension and endothelial dysfunction in hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Humans; Hypertension; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Nitro Compounds; Oxidative Stress; Rats; Rats, Inbred Dahl; Xanthine Dehydrogenase | 2018 |
Cellular mechanisms of metabolic syndrome-related atrial decompensation in a rat model of HFpEF.
Topics: Angiotensin II; Animals; Atrial Remodeling; Calcium; Calcium Signaling; Cell Nucleus; Cytosol; Disease Models, Animal; Excitation Contraction Coupling; Heart Atria; Heart Failure; Heart Ventricles; Hypertension; Metabolic Syndrome; Myocytes, Cardiac; Rats; Sarcoplasmic Reticulum; Stroke Volume | 2018 |
Fucoidan attenuates angiotensin II-induced abdominal aortic aneurysms through the inhibition of c-Jun N-terminal kinase and nuclear factor κB activation.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cells, Cultured; Collagenases; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phosphorylation; Polysaccharides; Protein Kinase Inhibitors; Signal Transduction; Transcription Factor RelA; Vascular Remodeling | 2018 |
A novel hamster nonalcoholic steatohepatitis model induced by a high-fat and high-cholesterol diet.
Topics: Angiotensin II; Animals; Body Weight; Cholesterol, Dietary; Chymases; Cricetinae; Diet, High-Fat; Disease Models, Animal; Liver; Liver Cirrhosis; Male; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Organ Size; Transforming Growth Factor beta | 2018 |
Modulating Role of Ang1-7 in Control of Blood Pressure and Renal Function in AngII-infused Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Male; Natriuresis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Urodynamics | 2018 |
Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Hypertension; Infusions, Intraventricular; Male; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 4; Neurons; Promoter Regions, Genetic; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Signal Transduction; Synapsins; Up-Regulation; Vacuolar Proton-Translocating ATPases | 2018 |
Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway.
Topics: Angiotensin II; Animals; Diabetic Cardiomyopathies; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Heart; Humans; Isothiocyanates; Male; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; Signal Transduction; Sulfoxides | 2018 |
Maternal high-fat diet acts on the brain to induce baroreflex dysfunction and sensitization of angiotensin II-induced hypertension in adult offspring.
Topics: Angiotensin II; Animal Nutritional Physiological Phenomena; Animals; Baroreflex; Blood Pressure; Brain; Cytokines; Diet, High-Fat; Disease Models, Animal; Female; Heart; Hypertension; Inflammation Mediators; Male; Maternal Nutritional Physiological Phenomena; NADPH Oxidases; Nutritional Status; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstriction | 2018 |
Myeloid CD11c
Topics: Angiotensin II; Animals; Antigen-Presenting Cells; Blood Pressure; CD11c Antigen; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Inflammation; Ion Transport; Mice; Mice, Transgenic; Myeloid Cells; Sodium Chloride, Dietary | 2018 |
Mouse macrophage specific knockout of SIRT1 influences macrophage polarization and promotes angiotensin II-induced abdominal aortic aneurysm formation.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Arginase; Cell Polarity; Disease Models, Animal; Humans; Lectins, C-Type; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Knockout; Nitric Oxide Synthase Type II; Receptors, Cell Surface; Signal Transduction; Sirtuin 1 | 2018 |
Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; Disease Models, Animal; Imaging, Three-Dimensional; Male; Mice; Mice, Inbred C57BL; Microscopy, Phase-Contrast; Synchrotrons | 2018 |
Osteoglycin attenuates cardiac fibrosis by suppressing cardiac myofibroblast proliferation and migration through antagonizing lysophosphatidic acid 3/matrix metalloproteinase 2/epidermal growth factor receptor signalling.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; ErbB Receptors; Fibrosis; Hypertension; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Myofibroblasts; Receptor Cross-Talk; Receptors, Lysophosphatidic Acid; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Ventricular Remodeling | 2018 |
Dose-Effect of Irbesartan on Cyclooxygenase-2 and Matrix Metalloproteinase-9 Expression in Rabbit Atherosclerosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Aortic Diseases; Atherosclerosis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Irbesartan; Lipids; Male; Matrix Metalloproteinase 9; NF-kappa B; Plaque, Atherosclerotic; Rabbits; Signal Transduction | 2018 |
Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm.
Topics: Acetates; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Chemokine CCL3; Cyclopropanes; Disease Models, Animal; Leukotriene Antagonists; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Quinolines; Receptors, Leukotriene; Sulfides | 2018 |
Cilostazol Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysms but Not Atherosclerosis in Apolipoprotein E-Deficient Mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atherosclerosis; Cell Adhesion Molecules; Cells, Cultured; Cilostazol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Endothelial Cells; Male; Mice, Knockout, ApoE; Phosphodiesterase 3 Inhibitors; Signal Transduction | 2018 |
Deletion of BMAL1 in Smooth Muscle Cells Protects Mice From Abdominal Aortic Aneurysms.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; ARNTL Transcription Factors; Binding Sites; Desoxycorticosterone Acetate; Dilatation, Pathologic; Disease Models, Animal; Elastin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Sodium Chloride, Dietary; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic | 2018 |
High fat diet-induced metabolically obese and normal weight rabbit model shows early vascular dysfunction: mechanisms involved.
Topics: Angiotensin II; Animals; Blood Glucose; Body Weight; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Male; Obesity; Rabbits; Random Allocation; Vasodilation | 2018 |
Lipid-Lowering Therapy With Ezetimibe Decreases Spontaneous Atherothrombotic Occlusions in a Rabbit Model of Plaque Erosion: A Role of Serum Oxysterols.
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Arterial Occlusive Diseases; Atherosclerosis; Biomarkers; Cells, Cultured; Cholesterol, Dietary; Diet, High-Fat; Disease Models, Animal; Down-Regulation; Ezetimibe; Femoral Artery; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Oxysterols; Plaque, Atherosclerotic; Rabbits; Rats; Rosuvastatin Calcium; Signal Transduction; Thrombosis; Vascular System Injuries | 2018 |
Inhibition of miR-155 attenuates abdominal aortic aneurysm in mice by regulating macrophage-mediated inflammation.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Movement; Cell Proliferation; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; MicroRNAs; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type II | 2018 |
Angiotensin II-induced Hypertension is Reduced by Deficiency of P-selectin Glycoprotein Ligand-1.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Interleukin-17; Membrane Glycoproteins; Mice; Mice, Knockout; Vasoconstrictor Agents | 2018 |
Abnormal Downregulation of Caveolin-3 Mediates the Pro-Fibrotic Action of MicroRNA-22 in a Model of Myocardial Infarction.
Topics: Actins; Angiotensin II; Animals; Base Sequence; Caveolin 3; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Disease Models, Animal; Down-Regulation; Fibroblasts; Fibrosis; Male; Mice; MicroRNAs; Myocardial Infarction; Myocardium; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; RNA Interference | 2018 |
Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Cell Survival; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Indoleamine-Pyrrole 2,3,-Dioxygenase; Macrophages; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, LDL; T-Lymphocytes | 2018 |
Ursolic acid prevents angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-knockout mice.
Topics: ADAM17 Protein; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Line; Cell Proliferation; Disease Models, Animal; Elastin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Ursolic Acid; Vascular Remodeling; Wound Healing | 2018 |
Acetone fraction from Sechium edule (Jacq.) S.w. edible roots exhibits anti-endothelial dysfunction activity.
Topics: Acetone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cinnamates; Cucurbitaceae; Disease Models, Animal; Endothelium, Vascular; Fatty Acids; Female; Losartan; Mexico; Mice; Mice, Inbred C57BL; Plant Extracts; Plant Roots; Vascular Diseases | 2018 |
Novel Role for the Immunoproteasome Subunit PSMB10 in Angiotensin II-Induced Atrial Fibrillation in Mice.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Cysteine Endopeptidases; Disease Models, Animal; Gene Expression Regulation; I-kappa B Kinase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Proteasome Endopeptidase Complex; Random Allocation; Reactive Oxygen Species; Reference Values; Sensitivity and Specificity; Signal Transduction; Up-Regulation | 2018 |
TRPM7 regulates angiotensin II-induced sinoatrial node fibrosis in sick sinus syndrome rats by mediating Smad signaling.
Topics: Angiotensin II; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fibrosis; Gene Expression Regulation; Immunohistochemistry; Male; Myocardium; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA; Sick Sinus Syndrome; Signal Transduction; Sinoatrial Node; Smad2 Protein; TRPM Cation Channels | 2018 |
Aspirin Reduces Cardiac Interstitial Fibrosis by Inhibiting Erk1/2-Serpine2 and P-Akt Signalling Pathways.
Topics: Actins; Angiotensin II; Animals; Aspirin; beta Catenin; Cell Line; Collagen Type I; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Phosphorylation; Proto-Oncogene Proteins c-akt; Serpin E2; Signal Transduction | 2018 |
CD40L Deficiency Protects Against Aneurysm Formation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; CD40 Ligand; Chemokines; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Humans; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout, ApoE; Tissue Inhibitor of Metalloproteinase-3 | 2018 |
MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-β-SMAD3 Signaling.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic Rupture; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Genetic Predisposition to Disease; JNK Mitogen-Activated Protein Kinases; Male; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Phosphorylation; Signal Transduction; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta | 2018 |
HDAC4 regulates vascular inflammation via activation of autophagy.
Topics: Acetylation; Angiotensin II; Animals; Autophagy; Cells, Cultured; Disease Models, Animal; Forkhead Box Protein O3; Histone Deacetylases; Male; Mice, Inbred C57BL; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasculitis | 2018 |
The oral administration of clarithromycin prevents the progression and rupture of aortic aneurysm.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Cells, Cultured; Clarithromycin; Disease Models, Animal; Elastin; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Macrophages; Male; Matrix Metalloproteinases, Secreted; Mice, Inbred C57BL; Mice, Knockout, ApoE; NF-kappa B; Phosphorylation; Vascular Remodeling | 2018 |
Atorvastatin Attenuates Metabolic Remodeling in Ischemic Myocardium through the Downregulation of UCP2 Expression.
Topics: Angiotensin II; Animals; Atorvastatin; Coronary Vessels; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Rats; Uncoupling Protein 2 | 2018 |
Co-administration of resveratrol with doxorubicin in young mice attenuates detrimental late-occurring cardiovascular changes.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Blood Pressure; Cardiotoxicity; Disease Models, Animal; Doxorubicin; Enzyme Activation; Heart Diseases; Hypertension; Male; Mice, Inbred C57BL; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Signal Transduction; Time Factors; Ventricular Remodeling | 2018 |
Mercaptoethanol Protects the Aorta from Dissection by Inhibiting Oxidative Stress, Inflammation, and Extracellular Matrix Degeneration in a Mouse Model.
Topics: Angiotensin II; Animals; Aorta; Aortic Dissection; Disease Models, Animal; Extracellular Matrix; Glutamate-Cysteine Ligase; Inflammation; Inflammation Mediators; Interleukin-1beta; Male; Mercaptoethanol; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Signal Transduction; Superoxide Dismutase-1; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2018 |
Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling.
Topics: ADAMTS1 Protein; ADAMTS5 Protein; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Extracellular Matrix; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, LDL; Tumor Suppressor Proteins; Vascular Remodeling; Versicans | 2018 |
Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium Signaling; Cell Line; Disease Models, Animal; Hypertension; Male; Mesenteric Arteries; Mice, Knockout, ApoE; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphorylation; Receptor, Angiotensin, Type 1; RGS Proteins; Vasoconstriction; Vasodilation | 2018 |
Plasma cholesterol lowering in an AngII‑infused atherosclerotic mouse model with moderate hypercholesterolemia.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoprotein B-100; Atherosclerosis; Cholesterol; Disease Models, Animal; Gene Expression Regulation; Hypercholesterolemia; Integrases; Male; Receptors, LDL | 2018 |
Angiotensin II Short-Loop Feedback: Is There a Role of Ang II for the Regulation of the Renin System In Vivo?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Female; Hypertension; Immunohistochemistry; Male; Mice; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2018 |
H19 Induces Abdominal Aortic Aneurysm Development and Progression.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Case-Control Studies; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pancreatic Elastase; Receptors, LDL; RNA, Long Noncoding; Swine; Swine, Miniature; Tumor Suppressor Protein p53; Up-Regulation | 2018 |
Acute Hyperthermia Inhibits TGF-β1-induced Cardiac Fibroblast Activation via Suppression of Akt Signaling.
Topics: Actins; Acute Disease; Angiotensin II; Animals; Disease Models, Animal; Fever; Fibroblasts; Humans; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Myocardium; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta1 | 2018 |
RANKL-mediated osteoclastogenic differentiation of macrophages in the abdominal aorta of angiotensin II-infused apolipoprotein E knockout mice.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Cell Transdifferentiation; Disease Models, Animal; Janus Kinase 2; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteoclasts; Osteogenesis; RANK Ligand; RAW 264.7 Cells; Signal Transduction; STAT5 Transcription Factor | 2018 |
Angiotensin II Promotes K
Topics: Angiotensin II; Animals; Blotting, Western; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; HSP90 Heat-Shock Proteins; Hypertension; KCNQ Potassium Channels; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Wistar; Vasodilation | 2018 |
Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Female; Humans; Hypertension; Male; Middle Aged; Rats; Rats, Wistar; Renin-Angiotensin System; Sex Factors; Zona Glomerulosa | 2018 |
Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Line; Disease Models, Animal; Female; Half-Life; Humans; Hypertension; Immunoglobulin Fc Fragments; Mice; Mice, Inbred BALB C; Peptidyl-Dipeptidase A; Recombinant Fusion Proteins; Renin; Renin-Angiotensin System; Treatment Outcome | 2018 |
Development and growth trends in angiotensin II-induced murine dissecting abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Apolipoproteins E; Disease Models, Animal; Disease Progression; Male; Mice; Ultrasonography | 2018 |
MicroRNA 199a-5p induces apoptosis by targeting JunB.
Topics: Angiotensin II; Animals; Apoptosis; Cell Line; Disease Models, Animal; Gene Expression Regulation; Heart Failure; MicroRNAs; Myocardial Infarction; Myocytes, Cardiac; Rats | 2018 |
Role of Wnt4/β-catenin, Ang II/TGFβ, ACE2, NF-κB, and IL-18 in attenuating renal ischemia/reperfusion-induced injury in rats treated with Vit D and pioglitazone.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; beta Catenin; Cytoprotection; Disease Models, Animal; Hydroxycholecalciferols; Intercellular Adhesion Molecule-1; Interleukin-18; Kidney; Kidney Diseases; Male; Neutrophil Infiltration; NF-kappa B; Peptidyl-Dipeptidase A; Peroxidase; Pioglitazone; Rats, Sprague-Dawley; Reperfusion Injury; Thiazolidinediones; Time Factors; Transforming Growth Factor beta; Wnt Signaling Pathway; Wnt4 Protein | 2018 |
C1QTNF1 attenuates angiotensin II-induced cardiac hypertrophy via activation of the AMPKa pathway.
Topics: Adipokines; AMP-Activated Protein Kinase Kinases; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Fibrosis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstrictor Agents | 2018 |
Aliskiren: Preclinical evidence for the treatment of hyperproliferative skin disorders.
Topics: Amides; Angiotensin II; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Cardiovascular System; Disease Models, Animal; Female; Fumarates; Inflammation; Keratinocytes; Mice; Psoriasis; Renin; Renin-Angiotensin System; Skin Diseases | 2018 |
Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor.
Topics: Angiotensin II; Animals; Collagen; Dipeptides; Disease Models, Animal; Fibrosis; GTP-Binding Proteins; Human Umbilical Vein Endothelial Cells; Humans; Mice; Myocardium; Myofibroblasts; Protein Glutamine gamma Glutamyltransferase 2; Small Molecule Libraries; Transforming Growth Factor beta1; Transglutaminases | 2018 |
Functional role of endothelial CXCL16/CXCR6-platelet-leucocyte axis in angiotensin II-associated metabolic disorders.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Aneurysm; Blood Platelets; Case-Control Studies; Cell Adhesion; Cells, Cultured; Chemokine CXCL16; Coculture Techniques; Disease Models, Animal; Endothelial Cells; Female; Humans; Leukocytes; Male; Metabolic Syndrome; Mice, Inbred C57BL; Mice, Knockout, ApoE; Middle Aged; Platelet Activation; Receptors, CXCR6; Signal Transduction | 2018 |
Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide.
Topics: Aged; Angiotensin II; Animals; Blood Pressure; Case-Control Studies; Cell Communication; Cell Differentiation; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Endothelial Cells; Female; Humans; Hydrogen Peroxide; Hypertension; Interleukin-6; Male; Mechanotransduction, Cellular; Mice, Inbred C57BL; Middle Aged; Monocytes; Nitric Oxide; Phenotype; STAT3 Transcription Factor; Stress, Mechanical | 2018 |
PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; beta-Galactosidase; Biomarkers; Cell Line; Chemokine CCL2; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Elastin; Humans; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Particulate Matter; Reactive Oxygen Species | 2018 |
Selective Insulin-like Growth Factor Resistance Associated with Heart Hemorrhages and Poor Prognosis in a Novel Preclinical Model of the Hematopoietic Acute Radiation Syndrome.
Topics: Acute Radiation Syndrome; Angiotensin II; Animals; Biopterins; C-Reactive Protein; Disease Models, Animal; Heart; Hematopoietic System; Hemorrhage; Insulin-Like Growth Factor I; Male; Nitric Oxide Synthase Type III; Prognosis; Radiation Tolerance; Signal Transduction; Swine; Swine, Miniature | 2018 |
The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Genetic Predisposition to Disease; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phenotype; Receptors, G-Protein-Coupled; Ventricular Dysfunction, Left; Ventricular Function, Left | 2018 |
Angiotensin II-Induced End-Organ Damage in Mice Is Attenuated by Human Exosomes and by an Exosomal Y RNA Fragment.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Exosomes; Humans; Hypertension; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; RNA | 2018 |
Adiponectin attenuates kidney injury and fibrosis in deoxycorticosterone acetate-salt and angiotensin II-induced CKD mice.
Topics: Adiponectin; Angiotensin II; Animals; Cell Proliferation; Desoxycorticosterone Acetate; Disease Models, Animal; Fibrosis; Hepatitis A Virus Cellular Receptor 1; Kidney; Lipocalin-2; Low Density Lipoprotein Receptor-Related Protein-2; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidases; Nephrectomy; Receptors, Cell Surface; Renal Insufficiency, Chronic; Signal Transduction; Transcription Factor RelA; Up-Regulation | 2018 |
IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
Topics: Aging; Angiotensin II; Animals; Cerebral Arteries; Cerebral Hemorrhage; Disease Models, Animal; Hypertension; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL | 2019 |
Drebrin regulates angiotensin II-induced aortic remodelling.
Topics: Angiotensin II; Animals; Aorta; Aortic Diseases; Arterial Pressure; Cell Proliferation; Disease Models, Animal; Extracellular Matrix; HEK293 Cells; Humans; Hypertension; Inflammation Mediators; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Neuropeptides; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling | 2018 |
CD1d-dependent natural killer T cells attenuate angiotensin II-induced cardiac remodelling via IL-10 signalling in mice.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antigens, CD1d; Cardiomegaly; Cells, Cultured; Coculture Techniques; Dendritic Cells; Disease Models, Animal; Fibrosis; Galactosylceramides; Hypertension; Inflammation Mediators; Interleukin-10; Male; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Natural Killer T-Cells; NF-kappa B; Signal Transduction; STAT3 Transcription Factor; Transforming Growth Factor beta1; Ventricular Remodeling | 2019 |
Modulation of synaptic inputs in magnocellular neurones in a rat model of cancer cachexia.
Topics: Angiotensin II; Animals; Cachexia; Cell Line, Tumor; Disease Models, Animal; Excitatory Postsynaptic Potentials; Male; Mannitol; Miniature Postsynaptic Potentials; Neoplasm Transplantation; Neoplasms; Neurons; Patch-Clamp Techniques; Rats; Supraoptic Nucleus | 2018 |
Median preoptic nucleus excitatory neurotransmitters in the maintenance of hypertensive state.
Topics: Angiotensin II; Animals; Disease Models, Animal; Glutamic Acid; Hypertension; Male; Preoptic Area; Rats, Inbred SHR; Rats, Wistar; Receptors, Neurotransmitter | 2018 |
Embelin inhibits abdominal aortic aneurysm through decreasing IL‑6‑induced STAT3 and NF‑κB inactivation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Benzoquinones; Disease Models, Animal; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Humans; Interleukin-6; Mice; NF-kappa B; Phosphorylation; STAT3 Transcription Factor | 2018 |
Benzbromarone Attenuates Oxidative Stress in Angiotensin II- and Salt-Induced Hypertensive Model Rats.
Topics: Angiotensin II; Animals; Antioxidants; Benzbromarone; Disease Models, Animal; Hypertension; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sodium Chloride, Dietary | 2018 |
Lipoxin A
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Line, Tumor; Disease Models, Animal; Humans; Imidazoles; Leucine; Lipopolysaccharides; Lipoxins; Male; Mice; NF-kappa B; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
Telmisartan protects chronic intermittent hypoxic mice via modulating cardiac renin-angiotensin system activity.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Chronic Disease; Disease Models, Animal; Endothelial Cells; Heart Diseases; Hypoxia; Male; Mice, Inbred C57BL; Mitochondria, Heart; Myocardium; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Telmisartan | 2018 |
α1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Aorta; Aortic Diseases; Cells, Cultured; Cytokines; Disease Models, Animal; Gene Deletion; Genetic Predisposition to Disease; Inflammation Mediators; Macrophages; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Phenotype; Signal Transduction; Vasodilation | 2018 |
Effect of a SGLT2 inhibitor on the systemic and intrarenal renin-angiotensin system in subtotally nephrectomized rats.
Topics: Administration, Oral; Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Glucosides; Glycosuria; Indoles; Kidney; Male; Nephrectomy; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2018 |
Network-based predictions of in vivo cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Computational Biology; Disease Models, Animal; Heart Failure; Humans; Mice; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Signal Transduction | 2018 |
A blockade of PI3Kγ signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model.
Topics: Angiotensin II; Animals; Cell Proliferation; Class Ib Phosphatidylinositol 3-Kinase; Cytokines; Disease Models, Animal; Fibroblasts; Fibrosis; Kidney; Mice; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinoxalines; Renal Insufficiency, Chronic; Thiazolidinediones | 2018 |
Effect of irradiation and bone marrow transplantation on angiotensin II-induced aortic inflammation in ApoE knockout mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Rupture; Aortitis; Atherosclerosis; Bone Marrow Transplantation; Disease Models, Animal; Macrophages; Male; Mice, Knockout, ApoE; Monocytes; Plaque, Atherosclerotic; Whole-Body Irradiation | 2018 |
PPARγ agonist rosiglitazone alters the temporal and spatial distribution of inflammation during abdominal aortic aneurysm formation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Disease Models, Animal; Inflammation; Male; Mice; Mice, Knockout; Models, Biological; PPAR gamma; Rosiglitazone; Th2 Cells; Thiazolidinediones; Vasodilator Agents | 2018 |
Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving 'SIRT1 and PGC-1α'.
Topics: Angiotensin II; Animals; Caloric Restriction; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Fibrosis; Hypertension; Male; Mice, Inbred C57BL; Myocardium; Obesity; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Ventricular Remodeling | 2018 |
Anti-hypertrophy effect of atorvastatin on myocardium depends on AMPK activation-induced miR-143-3p suppression via Foxo1.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Apoptosis; Atorvastatin; Cell Line; Cell Survival; Disease Models, Animal; Hypertrophy, Left Ventricular; Male; MicroRNAs; Myocytes, Cardiac; Nerve Tissue Proteins; Rats, Sprague-Dawley; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Cardiovascular Interactions between Fibroblast Growth Factor-23 and Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiovascular Diseases; Disease Models, Animal; Echocardiography; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Gene Expression; Male; Mice; Mice, Knockout; Myocardium; Rats; Rodentia; Signal Transduction | 2018 |
Hypertension-induced cognitive impairment: insights from prolonged angiotensin II infusion in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cognitive Dysfunction; Disease Models, Animal; Hypertension; Male; Memory, Short-Term; Mice; Motor Activity | 2018 |
Hydroxysafflor yellow A protects against angiotensin II‑induced hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Line; Chalcone; Disease Models, Animal; Heme Oxygenase-1; Male; Myocardial Infarction; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Protective Agents; Quinones; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Cilostazol ameliorates heart failure with preserved ejection fraction and diastolic dysfunction in obese and non-obese hypertensive mice.
Topics: Angiotensin II; Animals; Biomarkers; Biopsy; Blood Pressure; Cilostazol; Diastole; Disease Models, Animal; Disease Progression; Echocardiography; Energy Metabolism; Fibrosis; Heart Failure; Hypertension; Immunohistochemistry; Male; Mice; Renin; Stroke Volume; Vasodilator Agents; Ventricular Dysfunction, Left | 2018 |
A diet enriched with tree nuts reduces severity of atherosclerosis but not abdominal aneurysm in angiotensin II-infused apolipoprotein E deficient mice.
Topics: Angiotensin II; Animal Feed; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Diseases; Atherosclerosis; Brachiocephalic Trunk; Dilatation, Pathologic; Disease Models, Animal; Fatty Acids, Omega-3; Male; Mice, Knockout, ApoE; Nutritive Value; Nuts; Plaque, Atherosclerotic; Polyphenols; Severity of Illness Index; Time Factors | 2018 |
Reduction of cardiac TGFβ-mediated profibrotic events by inhibition of Hsp90 with engineered protein.
Topics: Angiotensin II; Animals; Cell Survival; Cells, Cultured; Collagen; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Fibrosis; Fluorescent Antibody Technique; HSP90 Heat-Shock Proteins; Mice; Mice, Knockout; Microscopy, Confocal; Models, Molecular; Myocardium; Peptides; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Signal Transduction; Transforming Growth Factor beta | 2018 |
The angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Kidney; Losartan; Malaria; Male; Mice, Inbred C57BL; Plasmodium berghei; Random Allocation; Receptor, Angiotensin, Type 1 | 2018 |
Local angiotensin II contributes to tumor resistance to checkpoint immunotherapy.
Topics: Angiotensin II; Animals; Antineoplastic Agents, Immunological; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cytokines; Disease Models, Animal; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Silencing; Humans; Immunotherapy; Inflammation Mediators; Mice; Molecular Targeted Therapy; Neoplasms; Signal Transduction; Tumor Escape; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2018 |
Telmisartan attenuates kidney apoptosis and autophagy-related protein expression levels in an intermittent hypoxia mouse model.
Topics: Angiotensin II; Animals; Apoptosis; Autophagy-Related Proteins; Blood Urea Nitrogen; Body Weight; Creatinine; Disease Models, Animal; Hypoxia; In Situ Nick-End Labeling; Kidney; Male; Mice; Mice, Inbred C57BL; Telmisartan | 2019 |
Angiotensin II upregulates CYP4A isoform expression in the rat kidney through angiotensin II type 1 receptor.
Topics: Angiotensin II; Animals; Arachidonic Acid; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cytochrome P-450 CYP4A; Disease Models, Animal; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Protein Isoforms; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles | 2018 |
Mechanism of vasoactive peptide intermedin in vascular collagen remodeling during angiotensin II-induced hypertention.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Collagen; Disease Models, Animal; Hypertension; Mitogen-Activated Protein Kinases; Peptide Hormones; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Vascular Remodeling | 2018 |
Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation.
Topics: Aminopropionitrile; Angiotensin II; Animals; Antigens, Differentiation; Antioxidants; Aortic Aneurysm; Chemokine CCL2; Cyclophilins; Disease Models, Animal; Elastin; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; Matrix Metalloproteinase 2; Mice; Nifedipine; Nitroso Compounds; Oxidative Stress; Photolysis; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2018 |
Angiotensin II requires an intact cardiac thyrotropin-releasing hormone (TRH) system to induce cardiac hypertrophy in mouse.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Disease Susceptibility; Drinking; Fibrosis; Gene Expression Profiling; Hypertrophy, Left Ventricular; Immunohistochemistry; Mice; Myocardium; NIH 3T3 Cells; Phenotype; Rats; RNA Interference; RNA, Small Interfering; Thyrotropin-Releasing Hormone | 2018 |
The mechanisms of Ang II-induced hypertensive vascular remodeling under suppression of CD68 in macrophages.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Disease Models, Animal; Hypertension; Macrophages; Male; Mice; Mice, Inbred C57BL; Vascular Remodeling | 2018 |
The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Phosphoprotein Phosphatases; Transforming Growth Factor beta1; Vascular Remodeling | 2019 |
MiR-101a ameliorates AngII-mediated hypertensive nephropathy by blockade of TGFβ/Smad3 and NF-κB signalling in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Base Sequence; Cell Line; Disease Models, Animal; Fibrosis; Hypertension, Renal; Kidney; Male; Mice; MicroRNAs; Nephritis; NF-kappa B; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta | 2019 |
Vascular angiotensin AT1 receptor neuromodulation in fetal programming of hypertension.
Topics: Angiotensin II; Animal Nutritional Physiological Phenomena; Animals; Arterial Pressure; Disease Models, Animal; Female; Gestational Age; Hypertension; Malnutrition; Maternal Nutritional Physiological Phenomena; Mesenteric Arteries; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System | 2019 |
NFAT5 regulates renal gene expression in response to angiotensin II through Annexin-A2-mediated posttranscriptional regulation in hypertensive rats.
Topics: Angiotensin II; Animals; Annexin A2; Arterial Pressure; Disease Models, Animal; Hypertension; Kidney; Male; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA Processing, Post-Transcriptional; Signal Transduction; Transcription Factors; Up-Regulation | 2019 |
LNK deficiency promotes acute aortic dissection and rupture.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta; Aortic Dissection; Aortic Rupture; Disease Models, Animal; Female; Genetic Predisposition to Disease; Homeodomain Proteins; Humans; Male; Mice; Mice, Knockout | 2018 |
IGF-1 regulates Ang II and VEGF signaling pathways in retinal neovascularization.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Insulin-Like Growth Factor I; Male; Mice, Inbred C57BL; Regional Blood Flow; Retinal Neovascularization; Retinal Vessels; RNA, Small Interfering; RNAi Therapeutics; Signal Transduction; Vascular Endothelial Growth Factor A | 2018 |
Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis.
Topics: Actins; Adventitia; Angiotensin II; Animals; Aorta; Aortic Diseases; Disease Models, Animal; Febuxostat; Fibroblasts; Fibrosis; Gout Suppressants; Hypertension; Macrophages; Male; Mice, Inbred C57BL; Transforming Growth Factor beta1; Vascular Remodeling; Xanthine Oxidase | 2019 |
Endocrine Effects of Simulated Complete and Partial Aortic Occlusion in a Swine Model of Hemorrhagic Shock.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Balloon Occlusion; Disease Models, Animal; Endocrine System; Hydrocortisone; Renin; Statistics, Nonparametric; Swine | 2019 |
Long-Term Effects of the Abdominal Aortic Aneurysm Model in Rabbits Prepared by Pancreatic Elastase Combined With Angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Hemodynamics; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pancreatic Elastase; Rabbits; Time Factors; Ultrasonography, Doppler, Color; Vascular Remodeling | 2019 |
Icariin ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting Nox2-containing NADPH oxidase activation.
Topics: Angiotensin II; Animals; Basilar Artery; Brain; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Flavonoids; Humans; Hyperplasia; Hypertension; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Phytotherapy; Rats, Sprague-Dawley; Reactive Oxygen Species; Stroke; Vascular Remodeling | 2019 |
MiR-130a-5p prevents angiotensin II-induced podocyte apoptosis by modulating M-type phospholipase A2 receptor.
Topics: Angiotensin II; Animals; Antagomirs; Apoptosis; Case-Control Studies; Cell Line; Disease Models, Animal; Female; Glomerulonephritis, Membranous; Humans; Mice, Inbred BALB C; MicroRNAs; Podocytes; Receptors, Phospholipase A2; Signal Transduction | 2018 |
Interleukin-12p35 knockout promotes macrophage differentiation, aggravates vascular dysfunction, and elevates blood pressure in angiotensin II-infused mice.
Topics: Adult; Aged; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Case-Control Studies; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Female; Humans; Hypertension; Interleukin-12; Interleukin-12 Subunit p35; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Phenotype; Signal Transduction; Vasoconstriction; Vasodilation | 2019 |
von Willebrand factor deficiency does not influence angiotensin II-induced abdominal aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Vasoconstrictor Agents; von Willebrand Factor | 2018 |
Licochalcone A attenuates abdominal aortic aneurysm induced by angiotensin II via regulating the miR-181b/SIRT1/HO-1 signaling.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Chalcones; Cytokines; Disease Models, Animal; Heme Oxygenase-1; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; MicroRNAs; Signal Transduction; Sirtuin 1 | 2019 |
Hyperoside Protects Against Pressure Overload-Induced Cardiac Remodeling via the AKT Signaling Pathway.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Oxidative Stress; Protective Agents; Proto-Oncogene Proteins c-akt; Quercetin; Rats; Signal Transduction; Superoxide Dismutase; Ventricular Remodeling | 2018 |
Testin protects against cardiac hypertrophy by targeting a calcineurin-dependent signalling pathway.
Topics: Adult; Aged; Angiotensin II; Animals; Calcineurin; Cardiomegaly; Cardiomyopathy, Dilated; Case-Control Studies; Cytoskeletal Proteins; Disease Models, Animal; Female; Humans; Male; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Cardiac; NFATC Transcription Factors; RNA-Binding Proteins | 2019 |
Active-site directed peptide l-Phe-d-His-l-Leu inhibits angiotensin converting enzyme activity and dexamethasone-induced hypertension in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Catalytic Domain; Dexamethasone; Disease Models, Animal; Hypertension; Kinetics; Male; Molecular Docking Simulation; Oligopeptides; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System | 2019 |
YAP activation promotes the transdifferentiation of cardiac fibroblasts to myofibroblasts in matrix remodeling of dilated cardiomyopathy.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Blotting, Western; Cardiomyopathy, Dilated; Cell Cycle Proteins; Cell Differentiation; Cell Transdifferentiation; Disease Models, Animal; Echocardiography; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Myofibroblasts; Phosphoproteins; Rats; Rats, Sprague-Dawley; Swine; YAP-Signaling Proteins | 2018 |
Chemokine (C-X-C motif) receptor 2 blockade by SB265610 inhibited angiotensin II-induced abdominal aortic aneurysm in Apo E
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Macrophages; Male; Mice; Mice, Knockout, ApoE; Phenylurea Compounds; Receptors, Interleukin-8B; Signal Transduction; Triazoles | 2019 |
The miRNA-184 drives renal fibrosis by targeting HIF1AN in vitro and in vivo.
Topics: Actins; Angiotensin II; Animals; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Databases, Genetic; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Kidney; Mice; MicroRNAs; Mixed Function Oxygenases; Rats; Renal Insufficiency, Chronic; RNA, Messenger; Ureteral Obstruction | 2019 |
Immunoproteasome Subunit β5i Promotes Ang II (Angiotensin II)-Induced Atrial Fibrillation by Targeting ATRAP (Ang II Type I Receptor-Associated Protein) Degradation in Mice.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Atrial Remodeling; Disease Models, Animal; Fibrosis; Heart Atria; Immunoproteins; Mice; Oxidative Stress; Proteasome Endopeptidase Complex; Receptor, Angiotensin, Type 1 | 2019 |
Fibroblast growth factor-21 protects against fibrosis in hypertensive heart disease.
Topics: Angiotensin II; Animals; Biopsy; Blood Pressure; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Fibroblast Growth Factors; Fibrosis; Gene Expression Regulation; Heart Rate; Heart Ventricles; Humans; Hypertension; Mice, Knockout; Myocardium; Rats, Sprague-Dawley; RNA, Messenger | 2019 |
Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Diseases; Arrhythmias, Cardiac; Arterial Pressure; Atherosclerosis; Cardiomegaly; Disease Models, Animal; Hypertension; Male; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Propionates; T-Lymphocytes, Regulatory; Th17 Cells | 2019 |
Microglial Cells Impact Gut Microbiota and Gut Pathology in Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Arterial Pressure; Autonomic Nervous System; Disease Models, Animal; Gastrointestinal Microbiome; Hypertension; Infusions, Intraventricular; Intestines; Male; Microglia; Paraventricular Hypothalamic Nucleus; Rats, Inbred SHR; Rats, Inbred WKY; Tetracyclines | 2019 |
Circular RNA microarray expression profile in 3,4-benzopyrene/angiotensin II-induced abdominal aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Benzo(a)pyrene; Disease Models, Animal; Gene Ontology; Gene Regulatory Networks; Male; Mice, Inbred C57BL; MicroRNAs; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Reproducibility of Results; RNA, Circular; Transcriptome | 2019 |
MicroRNA-375-3p inhibitor suppresses angiotensin II-induced cardiomyocyte hypertrophy by promoting lactate dehydrogenase B expression.
Topics: Angiotensin II; Animals; Aorta; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Gene Knockdown Techniques; Heart Failure; Humans; Isoenzymes; L-Lactate Dehydrogenase; MicroRNAs; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; Primary Cell Culture; Rats; Signal Transduction | 2019 |
Cerebral and skeletal muscle feed artery vasoconstrictor responses in a mouse model with greater large elastic artery stiffness.
Topics: Angiotensin II; Animals; Cerebral Arteries; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; Losartan; Male; Mice; Muscle, Skeletal; Norepinephrine; Receptor, Angiotensin, Type 1; Vascular Stiffness; Vasoconstriction; Vasoconstrictor Agents | 2019 |
Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Apelin; Biopsy; Cardiomegaly; Disease Models, Animal; Echocardiography; Fibrosis; Heart Failure; Hypertension; Mice; Mice, Knockout; Myocardial Contraction; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Ventricular Dysfunction; Ventricular Remodeling | 2019 |
NPR-C (Natriuretic Peptide Receptor-C) Modulates the Progression of Angiotensin II-Mediated Atrial Fibrillation and Atrial Remodeling in Mice.
Topics: Action Potentials; Angiotensin II; Animals; Atrial Fibrillation; Atrial Remodeling; Disease Models, Animal; Disease Progression; Fibrosis; Heart Atria; Heart Rate; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Receptors, Atrial Natriuretic Factor; Time Factors | 2019 |
SP1-SYNE1-AS1-miR-525-5p feedback loop regulates Ang-II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Proliferation; Cytoskeletal Proteins; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Humans; Mice; MicroRNAs; Myocytes, Cardiac; Nerve Tissue Proteins; RNA, Long Noncoding; Sp1 Transcription Factor; Transcriptional Activation | 2019 |
Interleukin-6 Receptor Signaling and Abdominal Aortic Aneurysm Growth Rates.
Topics: Alleles; Angiotensin II; Animals; Antibodies; Aortic Aneurysm, Abdominal; Biomarkers; Disease Models, Animal; Humans; Interleukin-6; Linear Models; Mice; Polymorphism, Single Nucleotide; Receptors, Interleukin-6; Signal Transduction; Survival Rate; Transforming Growth Factor beta | 2019 |
A novel role for myeloid endothelin-B receptors in hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Endocytosis; Endothelin-1; Humans; Hypertension; Macrophages; Mice; Receptor, Endothelin A; Receptor, Endothelin B | 2019 |
Down-regulation of miR-200c attenuates AngII-induced cardiac hypertrophy via targeting the MLCK-mediated pathway.
Topics: Angiotensin II; Animals; Antagomirs; Aorta; Apoptosis; Cardiomegaly; Constriction, Pathologic; Disease Models, Animal; Echocardiography; Gene Expression Regulation; Male; MicroRNAs; Myocytes, Cardiac; Myosin-Light-Chain Kinase; Oligoribonucleotides; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2019 |
Caloric Restriction Exacerbates Angiotensin II-Induced Abdominal Aortic Aneurysm in the Absence of p53.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Caloric Restriction; Disease Models, Animal; Energy Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Signal Transduction; Tumor Suppressor Protein p53 | 2019 |
CSN5 attenuates Ang II-induced cardiac hypertrophy through stabilizing LKB1.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Angiotensin II; Animals; Cardiomegaly; COP9 Signalosome Complex; Disease Models, Animal; Gene Expression Regulation; Humans; Mice; Myocytes, Cardiac; Peptide Hydrolases; Protein Binding; Protein Interaction Maps; Protein Kinases; Protein Serine-Threonine Kinases | 2019 |
Wnt/β-catenin regulates blood pressure and kidney injury in rats.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; beta Catenin; Blood Pressure; Blood Urea Nitrogen; Bridged Bicyclo Compounds, Heterocyclic; Collagen Type I; Creatinine; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Fibronectins; Gene Expression Regulation; Hypertension; Kidney; Male; Nephrectomy; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Wnt Proteins; Wnt Signaling Pathway | 2019 |
Dietary Nitrate Reduces Blood Pressure in Rats With Angiotensin II-Induced Hypertension via Mechanisms That Involve Reduction of Sympathetic Hyperactivity.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Dietary Supplements; Disease Models, Animal; Hypertension; Male; Nitrates; Nitric Oxide; Rats; Rats, Wistar; Sympathetic Nervous System | 2019 |
Knockdown of lncRNA
Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Disease Models, Animal; Extracellular Matrix; Gene Knockdown Techniques; Humans; Inflammation; Mice; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; RNA, Small Interfering | 2019 |
Novel Role of T Cells and IL-6 (Interleukin-6) in Angiotensin II-Induced Microvascular Dysfunction.
Topics: Adaptive Immunity; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Flow Cytometry; Hypertension; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Signal Transduction; T-Lymphocytes; Thrombosis | 2019 |
Complex Role for E-Prostanoid 4 Receptors in Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Dinoprostone; Disease Models, Animal; Hypertension; Infusions, Intravenous; Mice; Mice, Transgenic; Receptors, Prostaglandin E, EP4 Subtype; Rest; Signal Transduction; Vasoconstrictor Agents; Vasodilation | 2019 |
Angiotensin II-induced hypertension and cardiac hypertrophy are differentially mediated by TLR3- and TLR4-dependent pathways.
Topics: Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Hypertension; Immunity, Innate; Inflammation Mediators; Kidney; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptor, Angiotensin, Type 1; Signal Transduction; Toll-Like Receptor 3; Toll-Like Receptor 4 | 2019 |
DNA Damage Response Mediates Pressure Overload-Induced Cardiomyocyte Hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Cycle; Disease Models, Animal; DNA Damage; Mice; Myocytes, Cardiac | 2019 |
Monoamine oxidase inhibitors protect against coronary heart disease in rodent rat models: A pilot study.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Hemodynamics; Male; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Rats, Wistar | 2019 |
Sialyltransferase7A promotes angiotensin II-induced cardiomyocyte hypertrophy via HIF-1α-TAK1 signalling pathway.
Topics: Angiotensin II; Animals; Cell Line; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Humans; Hypertrophy, Left Ventricular; Hypoxia-Inducible Factor 1, alpha Subunit; Male; MAP Kinase Kinase Kinases; Myocytes, Cardiac; Rats, Wistar; RNA Interference; Sialyltransferases; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction.
Topics: Aging; Angiotensin II; Animals; Antigens, Differentiation; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Calcium-Binding Proteins; Cognitive Dysfunction; Disease Models, Animal; Genes, MHC Class II; Hippocampus; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia | 2019 |
c‑Jun/Ap‑1 is upregulated in an Ang II‑induced abdominal aortic aneurysm formation model and mediates Chop expression in mouse aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Gene Silencing; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Transcription Factor AP-1; Transcription Factor CHOP | 2019 |
Concurrent Molecular Magnetic Resonance Imaging of Inflammatory Activity and Extracellular Matrix Degradation for the Prediction of Aneurysm Rupture.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Contrast Media; Disease Models, Animal; Disease Progression; Elastin; Extracellular Matrix; Feasibility Studies; Ferrosoferric Oxide; Gadolinium DTPA; Inflammation Mediators; Magnetic Resonance Imaging; Male; Mice, Knockout, ApoE; Molecular Imaging; Predictive Value of Tests; Reproducibility of Results; Time Factors | 2019 |
ATG5-mediated autophagy suppresses NF-κB signaling to limit epithelial inflammatory response to kidney injury.
Topics: Angiotensin II; Animals; Autophagy; Autophagy-Related Protein 5; Cells, Cultured; Cytokines; Disease Models, Animal; Fibrosis; G2 Phase Cell Cycle Checkpoints; HEK293 Cells; Humans; Inflammation; Kidney; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Signal Transduction; Ureteral Obstruction | 2019 |
Angiotensin type 1a receptors in the median preoptic nucleus support intermittent hypoxia-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Hypoxia; Injections, Intraventricular; Male; Oxidative Stress; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2019 |
RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity.
Topics: Angiotensin II; Animals; Cullin Proteins; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; HEK293 Cells; Humans; Hypertension; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Nitric Oxide; rho GTP-Binding Proteins; rho-Associated Kinases; Vascular Stiffness; Vasodilation | 2019 |
Pancreatic AT1aR Deficiency Decreases Insulin Secretion in Obese C57BL/6 Mice.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Biomarkers; Blood Glucose; Diet, Fat-Restricted; Diet, High-Fat; Disease Models, Animal; Insulin; Insulin Resistance; Islets of Langerhans; Male; Mice, Inbred C57BL; Mice, Knockout; Obesity; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Secretory Pathway | 2019 |
MiR-204 regulates type 1 IP
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Humans; Hypertension; Inositol 1,4,5-Trisphosphate Receptors; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Muscle Contraction; Muscle, Smooth, Vascular; Vasoconstriction | 2019 |
MicroRNA-31 Regulates Immunosuppression in Ang II (Angiotensin II)-induced Hypertension by Targeting Ppp6C (Protein Phosphatase 6c).
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Hypertension; Immunity, Cellular; Immunosuppression Therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Phosphoprotein Phosphatases; RNA; T-Lymphocytes, Regulatory | 2019 |
miR-431-5p Knockdown Protects Against Angiotensin II-Induced Hypertension and Vascular Injury.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Hypertension; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; RNA; T-Lymphocytes, Regulatory; Vascular System Injuries | 2019 |
Kangxianling decoction prevents renal fibrosis in rats with 5/6 nephrectomy and inhibits Ang II-induced ECM production in glomerular mesangial cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Collagen; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Fibronectins; Fibrosis; Glomerular Mesangium; Kidney; Kidney Diseases; Male; MAP Kinase Signaling System; Mesangial Cells; Nephrectomy; Rats, Sprague-Dawley; Transforming Growth Factor beta; Up-Regulation | 2019 |
Smooth muscle-specific LKB1 deletion exaggerates angiotensin II-induced abdominal aortic aneurysm in mice.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Gene Deletion; Humans; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Sp1 Transcription Factor | 2019 |
Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms.
Topics: Adult; Aged; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Autophagy; Autophagy-Related Protein 5; Cell Lineage; Cell Plasticity; Cells, Cultured; Disease Models, Animal; Endoribonucleases; Female; Humans; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout, ApoE; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Protein Serine-Threonine Kinases; Signal Transduction | 2019 |
Connexin37-Dependent Mechanisms Selectively Contribute to Modulate Angiotensin II -Mediated Hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Connexins; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gap Junction alpha-4 Protein; Hypertension; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; NG-Nitroarginine Methyl Ester; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 2; Renin; Vasoconstrictor Agents | 2019 |
COA-Cl prevented TGF-β1-induced CTGF expression by Akt dephosphorylation in normal human dermal fibroblasts, and it attenuated skin fibrosis in mice models of systemic sclerosis.
Topics: Adenosine; Angiotensin II; Animals; Cell Line; Connective Tissue Growth Factor; Disease Models, Animal; Drug Evaluation, Preclinical; Fibroblasts; Fibrosis; Humans; Male; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt; Scleroderma, Systemic; Skin; Transforming Growth Factor beta1 | 2019 |
Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction.
Topics: Anemia, Megaloblastic; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Genetic Loci; Hypertension; Macrophages; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Mitochondria; Phenotype; Tetrahydrofolate Dehydrogenase; Ultrasonography | 2019 |
Chronic Angiotensin 1-7 Infusion Prevents Angiotensin-II-Induced Cognitive Dysfunction and Skeletal Muscle Injury in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Cerebrovascular Circulation; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Maze Learning; Mice; Muscle, Skeletal; Peptide Fragments; Rotarod Performance Test | 2019 |
Inhibition of STAT3 activation mediated by toll-like receptor 4 attenuates angiotensin II-induced renal fibrosis and dysfunction.
Topics: Aminosalicylic Acids; Angiotensin II; Animals; Benzenesulfonates; Cells, Cultured; Disease Models, Animal; Fibrosis; Humans; Hypertension, Renal; Infusions, Subcutaneous; Kidney Diseases; Mice; Mice, Inbred C57BL; Nephritis; RNA, Small Interfering; STAT3 Transcription Factor; Toll-Like Receptor 4 | 2019 |
Myocardin ablation in a cardiac-renal rat model.
Topics: Angiotensin II; Animals; Cardio-Renal Syndrome; Cardiomyopathy, Dilated; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Ventricles; Male; Myocytes, Cardiac; Nuclear Proteins; Rats; RNA Interference; RNA, Small Interfering; Trans-Activators; Transforming Growth Factor beta; Ventricular Function | 2019 |
Blood pressure lowering effect of Ficus deltoidea var kunstleri in spontaneously hypertensive rats: possible involvement of renin-angiotensin-aldosterone system, endothelial function and anti-oxidant system.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Captopril; Disease Models, Animal; Drugs, Chinese Herbal; Ficus; Hypertension; Losartan; Male; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Plant Extracts; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 2019 |
LncRNA H19 promotes vascular inflammation and abdominal aortic aneurysm formation by functioning as a competing endogenous RNA.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; Signal Transduction; Transcription, Genetic; Up-Regulation | 2019 |
Activation of ADAM17 (A Disintegrin and Metalloprotease 17) on Glutamatergic Neurons Selectively Promotes Sympathoexcitation.
Topics: ADAM17 Protein; Angiotensin II; Animals; Autonomic Nervous System; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Paraventricular Hypothalamic Nucleus; Sodium Chloride, Dietary | 2019 |
Testosterone inhibits aneurysm formation and vascular inflammation in male mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Flutamide; Inflammation; Interleukin-1beta; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Androgen; Testosterone | 2019 |
FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy.
Topics: Angiotensin II; Animals; Case-Control Studies; Cells, Cultured; Cytoskeleton; Disease Models, Animal; Focal Adhesion Kinase 1; Glomerular Filtration Barrier; Humans; Hypertension, Renal; Kidney; LIM-Homeodomain Proteins; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Nephritis; Neuropeptides; Podocytes; Proteinuria; rac1 GTP-Binding Protein; Transcription Factors | 2019 |
Stress-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Blockade of Angiotensin-Converting Enzyme or Tumor Necrosis Factor-α.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain; Captopril; Cytokines; Disease Models, Animal; Hypertension; Inflammation Mediators; Male; Microglia; Pentoxifylline; Rats, Long-Evans; Rats, Sprague-Dawley; Renin-Angiotensin System; Stress Disorders, Post-Traumatic; Tumor Necrosis Factor Inhibitors | 2019 |
Circulating miR-103a-3p contributes to angiotensin II-induced renal inflammation and fibrosis via a SNRK/NF-κB/p65 regulatory axis.
Topics: Adult; Angiotensin II; Animals; Case-Control Studies; Cells, Cultured; Disease Models, Animal; Female; Fibrosis; Glomerulonephritis; Healthy Volunteers; Humans; Hypertension, Renal; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Middle Aged; Nephritis; Primary Cell Culture; Protein Serine-Threonine Kinases; Transcription Factor RelA | 2019 |
Effect of captopril on the apoptosis of lung tissue induced by high tidal volume ventilation in vivo.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Captopril; Disease Models, Animal; Lung; Male; Rats, Wistar; Renin-Angiotensin System; Respiration, Artificial; Tidal Volume; Ventilator-Induced Lung Injury | 2020 |
Quantitative trait loci associated with angiotensin II and high-salt diet induced acute decompensated heart failure in Balb/CJ mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Chromosome Mapping; Diet; Disease Models, Animal; Echocardiography; Female; Genetic Linkage; Genetic Predisposition to Disease; Heart Failure; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Oligonucleotide Array Sequence Analysis; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Sodium Chloride, Dietary; Species Specificity; Thiobarbituric Acid Reactive Substances | 2019 |
Oridonin protects against cardiac hypertrophy by promoting P21-related autophagy.
Topics: Angiotensin II; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Autophagy; Cardiomegaly; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Diterpenes, Kaurane; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; RNA, Small Interfering | 2019 |
Renal Sympathetic Denervation Improves Outcomes in a Canine Myocardial Infarction Model.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Disease Models, Animal; Dogs; Echocardiography; Female; Heart; Heart Failure; Kidney; Male; Myocardial Infarction; Myocardium; Renal Artery; Renin-Angiotensin System; Sympathectomy; Sympathetic Nervous System; Ventricular Function, Left | 2019 |
Schizandrin B attenuates angiotensin II induced endothelial to mesenchymal transition in vascular endothelium by suppressing NF-κB activation.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclooctanes; Cytokines; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Gene Expression Regulation; Inflammation; Lignans; Male; Mice; Mice, Inbred C57BL; NF-kappa B p50 Subunit; Oxidative Stress; Phenotype; Polycyclic Compounds; Signal Transduction; Vascular Remodeling | 2019 |
Elevated bone marrow sympathetic drive precedes systemic inflammation in angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Bone Marrow; CD4-Positive T-Lymphocytes; Disease Models, Animal; Femur; Hypertension; Inflammation; Male; Microglia; Neuroimmunomodulation; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors | 2019 |
Gut Microbiota Plays a Central Role to Modulate the Plasma and Fecal Metabolomes in Response to Angiotensin II.
Topics: Angiotensin II; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Feces; Female; Gastrointestinal Microbiome; Hypertension; Metabolome; Mice; Mice, Inbred C57BL; Plasma; Random Allocation; Role | 2019 |
The role of monocyte chemotactic protein-induced protein 1 (MCPIP1) in angiotensin II-induced macrophage apoptosis and vulnerable plaque formation.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Disease Models, Animal; Endoplasmic Reticulum Stress; Losartan; Macrophages, Peritoneal; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Plaque, Atherosclerotic; RAW 264.7 Cells; Receptor, Angiotensin, Type 1; Ribonucleases; RNA, Small Interfering | 2019 |
High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension.
Topics: Adolescent; Adoptive Transfer; Adult; Angiotensin II; Animals; Aorta; Bacteria; Blood Pressure; CD11c Antigen; Colon; Cytokines; Dendritic Cells; Disease Models, Animal; Dysbiosis; Female; Gastrointestinal Microbiome; Humans; Hypertension; Inflammation; Lipids; Lymph Nodes; Male; Mice; Mice, Inbred C57BL; Middle Aged; Myeloid Cells; Peyer's Patches; RNA, Ribosomal, 16S; Sodium Chloride; Sodium Chloride, Dietary; Young Adult | 2019 |
Human umbilical cord mesenchymal stem cells pretreated with Angiotensin-II attenuate pancreas injury of rats with severe acute pancreatitis.
Topics: Acute Disease; Angiotensin II; Animals; Apoptosis; Culture Media, Conditioned; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Models, Biological; Neovascularization, Physiologic; Pancreas; Pancreatitis; Paracrine Communication; Rats; Umbilical Cord; Vascular Endothelial Growth Factor Receptor-2 | 2019 |
Endothelial Forkhead Box Transcription Factor P1 Regulates Pathological Cardiac Remodeling Through Transforming Growth Factor-β1-Endothelin-1 Signal Pathway.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; Fibrosis; Forkhead Transcription Factors; Heart Failure; Humans; Mice; Mice, Knockout; Myocardium; Nanotubes, Peptide; Repressor Proteins; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta1; Ventricular Remodeling | 2019 |
Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anthracosis; Captopril; Cell Differentiation; Cell Line; Collagen; Disease Models, Animal; Female; Hedgehog Proteins; Humans; Lung; Male; Middle Aged; Myofibroblasts; Oligopeptides; Peptide Fragments; Pulmonary Fibrosis; Rats, Wistar; Renin-Angiotensin System; Signal Transduction; Silicosis | 2019 |
Radiological assessment of effectiveness of soluble RAGE in attenuating Angiotensin II-induced LVH mouse model using in vivo 9.4T MRI.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertrophy, Left Ventricular; Linear Models; Magnetic Resonance Imaging, Cine; Male; Mice, Inbred C57BL; Receptor for Advanced Glycation End Products; Solubility | 2019 |
Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apelin; Apoptosis; Cardiovascular Agents; Diet, High-Fat; Disease Models, Animal; Female; Gene Knockdown Techniques; Humans; Male; Mice, Transgenic; Middle Aged; Myocytes, Smooth Muscle; Neprilysin; Oxidative Stress; Peptidyl-Dipeptidase A; Phenylephrine; Primary Cell Culture; Proteolysis; Receptors, LDL; RNA, Small Interfering; Vascular Remodeling | 2019 |
ERK1/2 communicates GPCR and EGFR signaling pathways to promote CTGF-mediated hypertrophic cardiomyopathy upon Ang-II stimulation.
Topics: Angiotensin II; Animals; Butadienes; Cardiomegaly; Cardiomyopathy, Hypertrophic; Cell Enlargement; Cell Line; Connective Tissue Growth Factor; Disease Models, Animal; ErbB Receptors; Heart Ventricles; MAP Kinase Signaling System; Myocytes, Cardiac; Nitriles; Phosphorylation; Rats; Receptors, G-Protein-Coupled; Signal Transduction | 2019 |
Protective effect of apelin preconditioning in a rat model of hepatic ischemia reperfusion injury; possible interaction between the apelin/APJ system, Ang II/AT1R system and eNOS.
Topics: Alanine Transaminase; Angiotensin II; Animals; Apelin; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Gene Expression; Ischemic Preconditioning; Liver; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Reperfusion Injury | 2019 |
Alteration of the IL-33-sST2 pathway in hypertensive patients and a mouse model.
Topics: Angiotensin II; Animals; Aorta; Case-Control Studies; Disease Models, Animal; Female; Humans; Hypertension; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred C57BL; Middle Aged; Receptors, Interleukin-1 | 2019 |
B-cell lymphoma/leukaemia 10 and angiotensin II-induced kidney injury.
Topics: Acute Kidney Injury; Albuminuria; Angiotensin II; Animals; B-Cell CLL-Lymphoma 10 Protein; Cell Movement; Disease Models, Animal; Fibrosis; Hepatitis A Virus Cellular Receptor 1; Kidney; Kidney Transplantation; Lipocalin-2; Macrophages; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Podocytes; T-Lymphocyte Subsets; Time Factors | 2020 |
Protective Effect of Angiotensin (1-7) on Silicotic Fibrosis in Rats.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Collagen Type I; Disease Models, Animal; Lung; Myofibroblasts; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Silicosis | 2019 |
Accelerated Marfan syndrome model recapitulates established signaling pathways.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Cardiomyopathies; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Fibrillin-1; Genetic Predisposition to Disease; Heterozygote; Marfan Syndrome; Mice, Mutant Strains; Mutation; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenotype; Phosphorylation; Signal Transduction; Smad2 Protein; Time Factors; Transforming Growth Factor beta | 2020 |
Tropoelastin: an in vivo imaging marker of dysfunctional matrix turnover during abdominal aortic dilation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Biomarkers; Contrast Media; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Extracellular Matrix; Humans; Magnetic Resonance Imaging; Mice, Knockout, ApoE; Predictive Value of Tests; Proof of Concept Study; Time Factors; Tropoelastin; Up-Regulation; Vascular Remodeling | 2020 |
MicroRNA-92b-3p suppresses angiotensin II-induced cardiomyocyte hypertrophy via targeting HAND2.
Topics: 3' Untranslated Regions; Angiotensin II; Animals; Basic Helix-Loop-Helix Transcription Factors; Cardiomegaly; Cardiomyopathy, Hypertrophic; Disease Models, Animal; Heart Defects, Congenital; Heart Failure; Heart Ventricles; Mice; Mice, Inbred C57BL; MicroRNAs; Myocardium; Myocytes, Cardiac; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2019 |
Sex-related differences in the intratubular renin-angiotensin system in two-kidney, one-clip hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Constriction; Disease Models, Animal; Estrogens; Female; Hypertension; Hypertrophy, Left Ventricular; Kidney Tubules; Macrophages; Male; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renal Artery; Renin-Angiotensin System; Sex Factors; Signal Transduction | 2019 |
A virus-induced kidney disease model based on organ-on-a-chip: Pathogenesis exploration of virus-related renal dysfunctions.
Topics: Absorption, Physiological; Angiotensin II; Animals; Cell Polarity; Disease Models, Animal; Dogs; Herpesvirus 1, Suid; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Lab-On-A-Chip Devices; Madin Darby Canine Kidney Cells; Microfluidics; Sodium | 2019 |
Targeting HSP90 attenuates angiotensin II-induced adventitial remodelling via suppression of mitochondrial fission.
Topics: Adventitia; Angiotensin II; Animals; Aorta, Thoracic; Benzoquinones; Calcineurin; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dynamins; Fibroblasts; HSP90 Heat-Shock Proteins; Hypertension; Lactams, Macrocyclic; Male; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Molecular Targeted Therapy; Phenotype; Reactive Oxygen Species; Signal Transduction; Vascular Remodeling | 2020 |
Kaempferol Prevents Against Ang II-induced Cardiac Remodeling Through Attenuating Ang II-induced Inflammation and Oxidative Stress.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Failure; Inflammation Mediators; Kaempferols; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2019 |
G-Protein-Coupled Estrogen Receptor Agonist G1 Improves Diastolic Function and Attenuates Cardiac Renin-Angiotensin System Activation in Estrogen-Deficient Hypertensive Rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cyclopentanes; Diastole; Disease Models, Animal; Estrogens; Female; Hypertension; Myocardium; Ovariectomy; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Quinolines; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Ventricular Dysfunction, Left; Ventricular Function, Left | 2019 |
Role of sodium/glucose cotransporter inhibition on a rat model of angiotensin II-dependent kidney damage.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzhydryl Compounds; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Glucose; Glucosides; Hypertension; Losartan; Male; Microvilli; Proteinuria; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2019 |
Role of leptin signaling in the pathogenesis of angiotensin II-mediated atrial fibrosis and fibrillation.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Atria; Leptin; Male; Mice; Mice, Inbred C57BL; Myocardium; Rats; Rats, Sprague-Dawley; Rats, Zucker; Signal Transduction | 2013 |
Effects of irbesartan on gene expression revealed by transcriptome analysis of left atrial tissue in a porcine model of acute rapid pacing in vivo.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Fibrillation; Biphenyl Compounds; Blotting, Western; Cell Line; Connective Tissue Growth Factor; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Heart Atria; Heart Rate; Irbesartan; Mice; Microarray Analysis; Myocytes, Cardiac; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Tetrazoles | 2013 |
Early interference with p44/42 mitogen-activated protein kinase signaling in hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Hypertension; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2013 |
Low-dose angiotensin II infusion restores vascular function in cerebral arteries of high salt-fed rats by increasing copper/zinc superoxide dimutase expression.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Cerebral Arteries; Copper; Disease Models, Animal; Hypertension; Infusions, Intravenous; Male; Rats; Rats, Inbred BN; Recovery of Function; Superoxide Dismutase; Vasoconstrictor Agents; Vasodilation | 2013 |
Glomerular repair retardation via blocking of angiotensin II type 1a receptor pathway in a mouse glomerulonephritis model.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Collagen Type IV; Crotalid Venoms; Disease Models, Animal; Glomerulonephritis; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Trimeresurus; Vascular Endothelial Growth Factor A | 2012 |
Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred Lew; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Tetrazoles | 2013 |
Antihypertensive actions of moderate hyperbilirubinemia: role of superoxide inhibition.
Topics: Acetophenones; Angiotensin II; Animals; Bilirubin; Blood Pressure; Disease Models, Animal; Drug Implants; Enzyme Inhibitors; Hyperbilirubinemia; Hypertension; Male; Mice; Mice, Inbred C57BL; Superoxides; Vasoconstrictor Agents | 2013 |
Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity.
Topics: Action Potentials; Adipose Tissue; Adrenal Glands; Analysis of Variance; Angiotensin II; Animals; Basic Helix-Loop-Helix Transcription Factors; Body Composition; Body Weight; Brain; Calorimetry; Cardiovascular System; Diet, High-Fat; Disease Models, Animal; Drinking; Eating; Energy Metabolism; Female; Gene Expression Regulation; In Vitro Techniques; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Obesity; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Receptor, Angiotensin, Type 1; Repressor Proteins; RNA, Messenger; Sodium Chloride; Telemetry | 2013 |
Central mineralocorticoid receptors and the role of angiotensin II and glutamate in the paraventricular nucleus of rats with angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Eplerenone; Glutamic Acid; Heart Rate; Hypertension; Infusions, Intravenous; Infusions, Intraventricular; Kynurenic Acid; Male; Mineralocorticoid Receptor Antagonists; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Glutamate; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone; Tetrazoles | 2013 |
An important role of matrix metalloproteinase-8 in angiogenesis in vitro and in vivo.
Topics: Aneurysm; Angiotensin I; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; beta Catenin; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Matrix Metalloproteinase 8; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Neovascularization, Physiologic; Plaque, Atherosclerotic; Platelet Endothelial Cell Adhesion Molecule-1; RNA Interference; Time Factors; Transfection | 2013 |
Angiotensin II-induced vascular dysfunction depends on interferon-γ-driven immune cell recruitment and mutual activation of monocytes and NK-cells.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Endothelium, Vascular; Interferon-gamma; Killer Cells, Natural; Male; Mice; Mice, Inbred C57BL; Monocytes; Oxidative Stress; Random Allocation; Reference Values; Vascular Diseases | 2013 |
Angiotensin II's role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic.
Topics: Amygdala; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Cholera Toxin; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Heart Rate; Imidazoles; Male; Microinjections; Neural Pathways; Pain; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium Lactate; Urocortins | 2013 |
TIMP3 is the primary TIMP to regulate agonist-induced vascular remodelling and hypertension.
Topics: Angiotensin II; Animals; Arterial Pressure; Carotid Arteries; Collagen; Disease Models, Animal; Elastin; Gelatinases; Hypertension; Matrix Metalloproteinase Inhibitors; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Vasoconstriction; Vasodilation | 2013 |
β-Arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arrestins; Benzamides; beta-Arrestin 2; beta-Arrestins; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinases; Chemokine CCL2; Chemokine CCL3; Cyclooxygenase 2; Disease Models, Animal; Elastic Tissue; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; Time Factors | 2013 |
Additional antihypertensive effect of magnesium supplementation with an angiotensin II receptor blocker in hypomagnesemic rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Dietary Supplements; Disease Models, Animal; Hypertension; Kidney; Magnesium; Magnesium Deficiency; Male; Rats; Rats, Sprague-Dawley; Systole; Time Factors | 2013 |
Enhanced angiotensin receptor-associated protein in renal tubule suppresses angiotensin-dependent hypertension.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; DNA; Gene Expression Regulation; Hypertension; Kidney Tubules, Distal; Male; Mice; Mice, Transgenic; Polymerase Chain Reaction; Renin-Angiotensin System | 2013 |
Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects.
Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Disease Progression; Inflammation Mediators; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Sirtuin 1; Time Factors; Tumor Necrosis Factor-alpha | 2013 |
Resveratrol suppresses microcirculatory disturbance in a rat model of severe acute pancreatitis.
Topics: Acute Disease; Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Endothelins; Microcirculation; Nitric Oxide; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Renin; Resveratrol; Stilbenes; Taurocholic Acid | 2013 |
Chemerin connects fat to arterial contraction.
Topics: Adipokines; Adipose Tissue; Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Chemokines; Disease Models, Animal; Gene Expression Regulation; Humans; Hypertension; Immunochemistry; Intercellular Signaling Peptides and Proteins; Mesenteric Arteries; Muscle, Smooth, Vascular; Obesity; Phenylephrine; Rats; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Vasoconstriction | 2013 |
Angiotensin II stimulates basolateral 10-pS Cl channels in the thick ascending limb.
Topics: Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Chloride Channels; Disease Models, Animal; Female; Hypertension; Loop of Henle; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2013 |
Real-time electrochemical detection of ATP and H₂O₂ release in freshly isolated kidneys.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Biosensing Techniques; Blood Pressure; Diet, Sodium-Restricted; Disease Models, Animal; Electrochemical Techniques; Equipment Design; Hydrogen Peroxide; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Microelectrodes; Perfusion; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary; Time Factors | 2013 |
Novel mechanism for disrupted circadian blood pressure rhythm in a rat model of metabolic syndrome--the critical role of angiotensin II.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Circadian Rhythm; Disease Models, Animal; Hypertension; Male; Metabolic Syndrome; Rats, Inbred SHR; Rats, Inbred WKY | 2013 |
Angiotensin II promotes thoracic aortic dissections and ruptures in Col3a1 haploinsufficient mice.
Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aorta, Thoracic; Aortic Dissection; Aortic Rupture; Collagen Type III; Disease Models, Animal; DNA; DNA Mutational Analysis; Dose-Response Relationship, Drug; Ehlers-Danlos Syndrome; Haploinsufficiency; Infusions, Intravenous; Mice; Mutation | 2013 |
Emerging role of angiotensin type 2 receptor (AT2R)/Akt/NO pathway in vascular smooth muscle cell in the hyperthyroidism.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Gene Expression Regulation; Hyperthyroidism; Male; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Proto-Oncogene Proteins c-akt; Rats; Receptor, Angiotensin, Type 2; Signal Transduction; Triiodothyronine; Vasoconstriction | 2013 |
Ang(1-7) treatment attenuates β-cell dysfunction by improving pancreatic microcirculation in a rat model of Type 2 diabetes.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type III; Pancreas; Peptide Fragments; Rats; Rats, Wistar | 2013 |
Angiotensin II is a new component involved in splenic T lymphocyte responses during Plasmodium berghei ANKA infection.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Adhesion; Cell Line; Cell Movement; Cytokines; Disease Models, Animal; Inflammation Mediators; Lymphocyte Activation; Malaria; Malaria, Cerebral; Mice; Plasmodium berghei; Spleen; T-Lymphocyte Subsets | 2013 |
Telmisartan inhibits AGE-induced podocyte damage and detachment.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blotting, Western; Cell Adhesion; Diabetic Nephropathies; Disease Models, Animal; DNA Damage; Glycation End Products, Advanced; L-Lactate Dehydrogenase; Mice; Podocytes; Telmisartan | 2013 |
ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Cytoprotection; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Naphthalenes; Neointima; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Resorcinols; Severity of Illness Index; Time Factors; Vasodilation | 2013 |
Antinociceptive response in transgenic mice expressing rat tonin.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Behavior, Animal; Disease Models, Animal; Losartan; Male; Mice; Mice, Transgenic; Nociception; Nociceptive Pain; Pain Measurement; Peptide Fragments; Rats; Receptors, G-Protein-Coupled; Tissue Kallikreins | 2013 |
Monoamine oxidases are mediators of endothelial dysfunction in the mouse aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation; Humans; Immunohistochemistry; Mice; Monoamine Oxidase; Oxidative Stress; Real-Time Polymerase Chain Reaction; RNA, Messenger; Umbilical Veins; Vascular Diseases; Vasodilation | 2013 |
Exploration of the mechanisms by which 3,4-benzopyrene promotes angiotensin II-induced abdominal aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Benzo(a)pyrene; Disease Models, Animal; Drug Administration Schedule; Injections, Intraperitoneal; Macrophages; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NF-kappa B; Smoking; Time Factors | 2014 |
Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Combined Modality Therapy; Dietary Supplements; Disease Models, Animal; Enzyme Inhibitors; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Epoxide Hydrolases; Fatty Acids, Omega-3; Hypertension, Renal; Inflammation Mediators; Kidney; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; Peptidyl-Dipeptidase A; Random Allocation; Solubility | 2013 |
Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin II via the T-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aorta; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation Mediators; Interleukin-17; Interleukin-6; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Th17 Cells; Tissue Culture Techniques | 2013 |
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Caspase 3; Cell Count; Diminazene; Disease Models, Animal; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glaucoma; Immunoenzyme Techniques; Intraocular Pressure; Male; Nerve Fibers; Ophthalmic Solutions; Optic Nerve; Peptide Fragments; Peptidyl-Dipeptidase A; Radionuclide Imaging; Rats; Rats, Wistar; Renin-Angiotensin System; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Tonometry, Ocular | 2013 |
Angiotensin II regulates microRNA-132/-212 in hypertensive rats and humans.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Endothelin-1; Female; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Mice; Mice, Inbred C57BL; MicroRNAs; Oligonucleotide Array Sequence Analysis; Organ Specificity; Rats, Sprague-Dawley; Reproducibility of Results; Vasoconstrictor Agents | 2013 |
Deficiency of senescence marker protein 30 exacerbates angiotensin II-induced cardiac remodelling.
Topics: Aging; Angiotensin II; Animals; Apoptosis; Ascorbic Acid; bcl-2-Associated X Protein; Biomarkers; Calcium-Binding Proteins; Cardiomegaly; Caspase 3; Disease Models, Animal; Fibrosis; Heart Failure; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Ventricular Remodeling | 2013 |
Prevention of TGFβ induction attenuates angII-stimulated vascular biglycan and atherosclerosis in Ldlr-/- mice.
Topics: Angiotensin II; Animals; Atherosclerosis; Biglycan; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Receptors, LDL; Transforming Growth Factor beta | 2013 |
Concentration of tissue angiotensin II increases with severity of experimental pancreatitis.
Topics: Acute Disease; Amylases; Angiotensin II; Animals; Disease Models, Animal; Male; Models, Biological; Pancreatitis; Rats; Severity of Illness Index; Taurocholic Acid; Time Factors | 2013 |
An ethanolic extract of Lindera obtusiloba stems, YJP-14, improves endothelial dysfunction, metabolic parameters and physical performance in diabetic db/db mice.
Topics: Albuminuria; Angiotensin II; Animals; Aorta; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium, Vascular; Ethanol; Exercise Tolerance; Gene Expression; Humans; Hyperglycemia; Hypoglycemic Agents; Lindera; Male; Mice; Mice, Transgenic; NADPH Oxidases; Nitric Oxide Synthase Type III; Pioglitazone; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Receptor, Angiotensin, Type 1; Thiazolidinediones | 2013 |
Essential role of angiotensin receptors in the modulation of intestinal epithelial cell apoptosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Apoptosis Regulatory Proteins; Disease Models, Animal; Enterocytes; Gene Expression Regulation; HT29 Cells; Humans; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Short Bowel Syndrome; Signal Transduction | 2013 |
The renin angiotensin system regulates Kupffer cells in colorectal liver metastases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colorectal Neoplasms; Disease Models, Animal; Gadolinium; Kupffer Cells; Liver Neoplasms; Macrophages; Male; Mice; Mice, Inbred CBA; Peptide Fragments; Renin-Angiotensin System | 2013 |
Critical role of matrix metalloproteinase-9 in acute cold exposure-induced stroke in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Brain; Disease Models, Animal; Doxycycline; Hypertension, Renovascular; Hypothermia, Induced; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Stroke; Time Factors | 2013 |
Periaortic adipose tissue-specific activation of the renin-angiotensin system contributes to atherosclerosis development in uninephrectomized apoE-/- mice.
Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensinogen; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Cholesterol, Dietary; Disease Models, Animal; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; PPAR gamma; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2013 |
A modified rat model of exercise-induced renal injury and the protective effects of losartan and yishen huanji decoction.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Urea Nitrogen; Disease Models, Animal; Drugs, Chinese Herbal; Environment; Losartan; Male; Motor Activity; Protective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome; Urinalysis | 2013 |
Blood pressure-renal blood flow relationships in conscious angiotensin II- and phenylephrine-infused rats.
Topics: Angiotensin II; Animals; Blood Pressure; Consciousness; Disease Models, Animal; Heart Rate; Hemodynamics; Hypertension; Infusions, Intravenous; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Renal Circulation; Telemetry; Vasoconstrictor Agents | 2013 |
β-Carotene Attenuates Angiotensin II-Induced Aortic Aneurysm by Alleviating Macrophage Recruitment in Apoe(-/-) Mice.
Topics: alpha-Tocopherol; Angiotensin II; Animals; Antioxidants; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; beta Carotene; Cholesterol, LDL; Dietary Supplements; Disease Models, Animal; Lymphocytes; Macrophages; Male; Mice, Knockout; Organ Size; Plaque, Atherosclerotic | 2013 |
Angiotensin II inhibits satellite cell proliferation and prevents skeletal muscle regeneration.
Topics: Angiotensin II; Animals; Cell Count; Cell Cycle Proteins; Cell Proliferation; Disease Models, Animal; Heart Failure; Mice; Muscle, Skeletal; Receptor, Angiotensin, Type 1; Receptors, Notch; Regeneration; Satellite Cells, Skeletal Muscle; Signal Transduction; Wasting Syndrome | 2013 |
Fluorofenidone inhibits nicotinamide adeninedinucleotide phosphate oxidase via PI3K/Akt pathway in the pathogenesis of renal interstitial fibrosis.
Topics: Angiotensin II; Animals; Antioxidants; Cell Line; Class Ia Phosphatidylinositol 3-Kinase; Collagen Type I; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; Kidney Diseases; Kidney Tubules; Lipid Peroxidation; Losartan; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridones; Rats; Rats, Sprague-Dawley; Signal Transduction; Transfection; Ureteral Obstruction | 2013 |
Contributions of leukocyte angiotensin-converting enzyme to development of atherosclerosis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atherosclerosis; Bone Marrow Transplantation; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Enalapril; Hypercholesterolemia; Leukocytes; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Receptors, LDL; Transplantation Chimera | 2013 |
[Effects of sapindus saponins on inflammatory response mediated by Ang II/p38MAPK pathway and cardiac hypertrophy in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Sapindus; Saponins | 2013 |
Upregulation of Nox4 promotes angiotensin II-induced epidermal growth factor receptor activation and subsequent cardiac hypertrophy by increasing ADAM17 expression.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Male; Myocardium; NADPH Oxidase 4; NADPH Oxidases; Rats; Rats, Sprague-Dawley; RNA; Signal Transduction; Transcriptional Activation; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
MicroRNA-22 downregulation by atorvastatin in a mouse model of cardiac hypertrophy: a new mechanism for antihypertrophic intervention.
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Atorvastatin; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Down-Regulation; Heptanoic Acids; Male; Mice; MicroRNAs; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; Oligonucleotides, Antisense; Phosphoric Monoester Hydrolases; PTEN Phosphohydrolase; Pyrroles; Rats | 2013 |
AVE 0991, a non-peptide mimic of angiotensin-(1-7) effects, attenuates pulmonary remodelling in a model of chronic asthma.
Topics: Airway Remodeling; Angiotensin I; Angiotensin II; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chronic Disease; Cytokines; Disease Models, Animal; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Mice; Mice, Inbred BALB C; Molecular Mimicry; Ovalbumin; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Artery; Pulmonary Veins; Receptors, G-Protein-Coupled; Time Factors | 2013 |
Metformin treatment improves erectile function in an angiotensin II model of erectile dysfunction.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Antihypertensive Agents; Arterial Pressure; Disease Models, Animal; Erectile Dysfunction; Humans; Hypertension; Male; Metformin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penile Erection; Penis; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Lipopolysaccharides; Losartan; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Vasodilator Agents | 2013 |
Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Down-Regulation; Fibrosis; Heart; Hypertension; Inflammation; Male; Mice; Mice, Knockout; MicroRNAs; Myocardium; NF-kappa B; Signal Transduction; Smad7 Protein | 2013 |
Protective effects of angiotensin-(1-7) administrated with an angiotensin-receptor blocker in a rat model of chronic kidney disease.
Topics: Angiopoietins; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Fibronectins; Losartan; Male; Nephrectomy; Peptide Fragments; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Receptor, TIE-2; Renal Insufficiency, Chronic; Systole | 2013 |
Natural regulatory T cells limit angiotensin II-induced aneurysm formation and rupture in mice.
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; B7-1 Antigen; B7-2 Antigen; CD28 Antigens; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Inflammation Mediators; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Leukocyte Reduction Procedures; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; T-Lymphocytes, Regulatory; Time Factors | 2013 |
AT1 receptors prevent salt-induced vascular dysfunction in isolated middle cerebral arteries of 2 kidney-1 clip hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Endothelium, Vascular; Hypertension, Renovascular; Male; Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Sodium Chloride; Vasoconstrictor Agents; Vasodilator Agents | 2013 |
Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
Topics: Actins; Adaptation, Physiological; Aging; Angiotensin II; Animals; Behavior, Animal; Blood-Brain Barrier; Cerebrovascular Circulation; Cytokines; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microvessels; Middle Cerebral Artery; TRPC Cation Channels; TRPC6 Cation Channel; Up-Regulation | 2013 |
Immunosuppressive drug azathioprine reduces aneurysm progression through inhibition of Rac1 and c-Jun-terminal-N-kinase in endothelial cells.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm; Aortic Rupture; Apolipoproteins E; Azathioprine; Cell Line, Tumor; Coculture Techniques; Disease Models, Animal; Disease Progression; Endothelial Cells; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Immunosuppressive Agents; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Mercaptopurine; Mice; Mice, Knockout; Monocytes; Neuropeptides; Phosphorylation; Protein Kinase Inhibitors; rac1 GTP-Binding Protein; Signal Transduction | 2013 |
ACE inhibition with captopril retards the development of signs of neurodegeneration in an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Regeneration; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Plaque, Amyloid; Protein Transport; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Transcriptome; Up-Regulation | 2013 |
Effects of nicotine on cardiovascular remodeling in a mouse model of systemic hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Disease Models, Animal; Hypertension; Infusion Pumps; Male; Mice; Mice, Inbred C57BL; Nicotine; Treatment Outcome; Ventricular Remodeling | 2013 |
Combination therapy with atorvastatin and amlodipine suppresses angiotensin II-induced aortic aneurysm formation.
Topics: Amlodipine; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Atorvastatin; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Drug Therapy, Combination; Enzyme Activation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Pyrroles; rho-Associated Kinases | 2013 |
Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Loop of Henle; Male; Ouabain; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase | 2013 |
Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Ganglionic Blockers; Hypertension; Ketoprofen; Male; Membrane Proteins; Norepinephrine; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sulfonamides; Sympathetic Nervous System; Time Factors | 2013 |
Brain angiotensin-converting enzyme type 2 shedding contributes to the development of neurogenic hypertension.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Autonomic Nervous System; Baroreflex; Blood Pressure; Brain; Desoxycorticosterone Acetate; Disease Models, Animal; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA Interference; Time Factors | 2013 |
Effect of aerobic exercise on miRNA-TLR4 signaling in atherosclerosis.
Topics: Angiotensin II; Animals; Atherosclerosis; Disease Models, Animal; Endothelin-1; Epidermal Growth Factor; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; MicroRNAs; NF-kappa B; Physical Conditioning, Animal; Signal Transduction; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4 | 2014 |
Upregulation of M₃ muscarinic receptor inhibits cardiac hypertrophy induced by angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiomegaly; Disease Models, Animal; Down-Regulation; Enzyme Activation; Heart Rate; MAP Kinase Signaling System; Mice; Mice, Transgenic; Myocardium; Organ Specificity; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Muscarinic M3; Up-Regulation | 2013 |
A novel heart failure mice model of hypertensive heart disease by angiotensin II infusion, nephrectomy, and salt loading.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Cells, Cultured; Disease Models, Animal; Disease Progression; Fibrosis; Gene Expression Regulation; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Myocardium; Nephrectomy; Neuropeptides; Oxidative Stress; Pulmonary Edema; rac1 GTP-Binding Protein; Rats; Rats, Wistar; Sodium Chloride, Dietary; Time Factors; Ventricular Function, Left | 2013 |
Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension.
Topics: Angiotensin II; Animals; CSK Tyrosine-Protein Kinase; Cyclic N-Oxides; Cytoplasm; Disease Models, Animal; Electron Transport; Endothelial Cells; Gene Silencing; Humans; Hydrogen Peroxide; Hypertension; Malates; Membrane Glycoproteins; Mice; Mice, Knockout; Mitochondria, Heart; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Protein Isoforms; Protein Transport; Reactive Oxygen Species; RNA Interference; src-Family Kinases; Superoxides | 2014 |
L-type calcium channel inhibitor diltiazem prevents aneurysm formation by blood pressure-independent anti-inflammatory effects.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm; Apolipoproteins E; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Diltiazem; Disease Models, Animal; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Transcription Factor AP-1 | 2013 |
Inhalation of diesel exhaust does not exacerbate cardiac hypertrophy or heart failure in two mouse models of cardiac hypertrophy.
Topics: Air Pollutants; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Disease Progression; Echocardiography; Heart Failure; Heart Rate; Inhalation Exposure; Male; Mice; Mice, Inbred C57BL; Particle Size; Particulate Matter; Time Factors; Vehicle Emissions | 2013 |
Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading.
Topics: Albuminuria; Amides; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cytoprotection; Disease Models, Animal; Disease Progression; Down-Regulation; Fumarates; Humans; Hydralazine; Hypertension; Kidney; Kidney Diseases; Mice; Mice, Transgenic; Ramipril; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2014 |
The protective effect of Liu-Wei-Di-Huang-Fang in salt-sensitive hypertension rats.
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Insulin; Male; Rats; Rats, Sprague-Dawley; Renin; Sodium Chloride, Dietary | 2014 |
Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; bcl-X Protein; Bleomycin; Cells, Cultured; Collagen Type I; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Infusions, Subcutaneous; Lung; Male; MAP Kinase Signaling System; NF-kappa B; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Pneumonia; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2014 |
Activation of angiotensin II type 1 receptor-associated protein exerts an inhibitory effect on vascular hypertrophy and oxidative stress in angiotensin II-mediated hypertension.
Topics: Adaptor Proteins, Signal Transducing; Aldehydes; Angiotensin II; Animals; Aorta; Cells, Cultured; Cytochrome b Group; Disease Models, Animal; Hypertension; Hypertrophy; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection | 2013 |
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
Topics: Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Heart Ventricles; Humans; Hypertrophy; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Neurotransmitter Agents; Nitric Oxide Synthase; Receptors, Adrenergic, beta-3; Signal Transduction; Ventricular Remodeling | 2014 |
Angiotensin-(1-7) modulates renal vascular resistance through inhibition of p38 mitogen-activated protein kinase in apolipoprotein E-deficient mice.
Topics: Angiotensin I; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Female; Hypertension, Renal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthalenes; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyrazoles; Receptors, G-Protein-Coupled; Renal Circulation; Vascular Resistance | 2014 |
Deletion of angiotensin-converting enzyme 2 promotes the development of atherosclerosis and arterial neointima formation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Femoral Artery; Gene Deletion; Genetic Predisposition to Disease; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Peptidyl-Dipeptidase A; Phenotype; Plaque, Atherosclerotic; Protein Kinase Inhibitors; RNA Interference; Signal Transduction; Transfection; Vascular System Injuries | 2014 |
Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading.
Topics: Angiotensin II; Animals; Autophagy; Autophagy-Related Protein 5; Cardiomegaly; Disease Models, Animal; Heart Ventricles; Mice; Mice, Mutant Strains; Microtubule-Associated Proteins | 2013 |
Angiotensin type 1a receptor-deficient mice develop diabetes-induced cardiac dysfunction, which is prevented by renin-angiotensin system inhibitors.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Down-Regulation; Fumarates; Kallikreins; Kininogens; Kinins; Mice; Mice, Knockout; Myocytes, Cardiac; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles; Ultrasonography; Valine; Valsartan | 2013 |
Endothelium-dependent relaxation and angiotensin II sensitivity in experimental preeclampsia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Female; Imidazoles; Lipopolysaccharides; Losartan; Nitric Oxide Synthase Type II; Pre-Eclampsia; Pregnancy; Prostaglandins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilator Agents | 2013 |
Zoledronate attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of Rho/ROCK-dependent JNK and NF-κB pathway.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Adhesion; Cell Line; Coculture Techniques; Dilatation, Pathologic; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Elastin; Endothelial Cells; Enzyme Activation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; NF-kappa B; Phosphorylation; Receptors, LDL; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vascular Cell Adhesion Molecule-1; Zoledronic Acid | 2013 |
Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na⁺-HCO₃⁻ cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: role of the renin-angiotensin system.
Topics: Ammonium Compounds; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Bicarbonates; Cardiomegaly; Disease Models, Animal; Down-Regulation; Endosomes; Hydrogen-Ion Concentration; Hyperkalemia; Hypertension; Losartan; Male; Myocytes, Cardiac; Potassium; Protein Transport; Rats; Rats, Inbred SHR; Rats, Wistar; Renin-Angiotensin System; Sarcolemma; Sodium-Bicarbonate Symporters; Time Factors | 2014 |
Podocyte injury enhances filtration of liver-derived angiotensinogen and renal angiotensin II generation.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antibodies, Monoclonal; Disease Models, Animal; Exotoxins; Genotype; Kidney Diseases; Kidney Tubules, Proximal; Liver; Membrane Proteins; Mice, Knockout; Phenotype; Podocytes; RNA, Messenger; Sodium; Time Factors; Up-Regulation | 2014 |
Ang II-salt hypertension depends on neuronal activity in the hypothalamic paraventricular nucleus but not on local actions of tumor necrosis factor-α.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; GABA-A Receptor Agonists; Hypertension; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tumor Necrosis Factor-alpha | 2014 |
Telmisartan ameliorates fibrocystic liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease.
Topics: Angiotensin II; Animals; Benzimidazoles; Benzoates; Blood Pressure; Cell Proliferation; Cysts; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Hepatocytes; Humans; Kidney Function Tests; Liver; Liver Diseases; Liver Function Tests; Male; Organ Size; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Transforming Growth Factor beta | 2013 |
Endogenous endothelin 1 mediates angiotensin II-induced hypertrophy in electrically paced cardiac myocytes through EGFR transactivation, reactive oxygen species and NHE-1.
Topics: Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Cats; Disease Models, Animal; Electric Stimulation; Endothelin-1; ErbB Receptors; Hypertrophy; Myocytes, Cardiac; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Signal Transduction; Sodium-Hydrogen Exchangers; Transcriptional Activation | 2014 |
COX2 inhibition during nephrogenic period induces ANG II hypertension and sex-dependent changes in renal function during aging.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Female; Glomerular Filtration Rate; Hypertension; Kidney; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2014 |
Mechanisms with clinical implications for atrial fibrillation-associated remodeling: cathepsin K expression, regulation, and therapeutic target and biomarker.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Atrial Fibrillation; Biomarkers; Cardiac Pacing, Artificial; Case-Control Studies; Cathepsin K; Cells, Cultured; Disease Models, Animal; Female; Fibrosis; Heart Atria; Humans; Male; Middle Aged; Myocytes, Cardiac; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphopeptides; Phosphorylation; Procollagen; Protein Kinase Inhibitors; Rabbits; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Signal Transduction; Superoxides; Up-Regulation | 2013 |
Circulating angiotensin II gains access to the hypothalamus and brain stem during hypertension via breakdown of the blood-brain barrier.
Topics: Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain Stem; Disease Models, Animal; Hypertension; Hypothalamus; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 2014 |
Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aortic Diseases; CD4 Antigens; CD8 Antigens; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Fibroblasts; Homeodomain Proteins; Hypertension; Inflammation; Interleukin-17; Male; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Stress, Mechanical; T-Lymphocytes; Vascular Stiffness; Vasculitis; Vasoconstrictor Agents | 2014 |
Notch γ-secretase inhibitor dibenzazepine attenuates angiotensin II-induced abdominal aortic aneurysm in ApoE knockout mice by multiple mechanisms.
Topics: Amyloid Precursor Protein Secretases; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Dibenzazepines; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Notch1; Signal Transduction | 2013 |
Fructose stimulates Na/H exchange activity and sensitizes the proximal tubule to angiotensin II.
Topics: Angiotensin II; Animals; Biological Transport; Disease Models, Animal; Fructose; Hydrogen-Ion Concentration; Hypertension; Kidney Tubules, Proximal; Rats; Sodium-Hydrogen Exchangers; Sweetening Agents | 2014 |
M-atrial natriuretic peptide and nitroglycerin in a canine model of experimental acute hypertensive heart failure: differential actions of 2 cGMP activating therapeutics.
Topics: Aldosterone; Angiotensin II; Animals; Arterial Pressure; Atrial Natriuretic Factor; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Enzyme Activation; Enzyme Activators; Guanylate Cyclase; Heart Failure; Hypertension; Male; Natriuresis; Nitroglycerin; Pulmonary Wedge Pressure; Receptors, Cytoplasmic and Nuclear; Renal Circulation; Soluble Guanylyl Cyclase; Time Factors | 2014 |
Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Hypertrophy; I-kappa B Kinase; In Vitro Techniques; Interferon Regulatory Factor-7; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; NF-kappa B; Signal Transduction | 2014 |
Altered reactivity of resistance vasculature contributes to hypertension in elastin insufficiency.
Topics: Angiotensin II; Animals; Arterial Pressure; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Elastin; Endothelium, Vascular; Genetic Predisposition to Disease; Haploinsufficiency; Hemizygote; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 2; rho-Associated Kinases; Signal Transduction; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2014 |
Angiotensin-converting enzyme (ACE and ACE2) imbalance correlates with the severity of cerulein-induced acute pancreatitis in mice.
Topics: Acute Disease; Amylases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Ceruletide; Disease Models, Animal; Genotype; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Pancreas; Pancreatitis; Peptide Fragments; Peptidyl-Dipeptidase A; Phenotype; Severity of Illness Index; Time Factors | 2014 |
Antagonist of C5aR prevents cardiac remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Agents; Collagen; Connective Tissue Growth Factor; Cytokines; Disease Models, Animal; Fibrosis; Hypertension; Mice, Inbred C57BL; Myocardium; Peptides, Cyclic; Receptor, Anaphylatoxin C5a; RNA, Messenger; Time Factors; Transforming Growth Factor beta1; Ventricular Remodeling | 2014 |
Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertension.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Autocrine Communication; Disease Models, Animal; Fibrosis; Hypertension; Kidney; Male; Myocardium; Paracrine Communication; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Ventricular Remodeling | 2014 |
Castration of male mice prevents the progression of established angiotensin II-induced abdominal aortic aneurysms.
Topics: Actins; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Cells, Cultured; Collagen; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Male; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Risk Factors; Sex Factors; Testosterone; Time Factors; Ultrasonography; Vascular Remodeling | 2015 |
Angiotensin-converting enzyme 2-independent action of presumed angiotensin-converting enzyme 2 activators: studies in vivo, ex vivo, and in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diminazene; Disease Models, Animal; Glutamyl Aminopeptidase; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Xanthones | 2014 |
Deletion of soluble epoxide hydrolase attenuates cardiac hypertrophy via down-regulation of cardiac fibroblasts-derived fibroblast growth factor-2.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Epoxide Hydrolases; Fibroblast Growth Factor 2; Fibroblasts; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Myocardium; Myocytes, Cardiac; Prospective Studies; Real-Time Polymerase Chain Reaction; Vasoconstrictor Agents | 2014 |
Phosphoinositide kinases play key roles in norepinephrine- and angiotensin II-induced increase in phosphatidylinositol 4,5-bisphosphate and modulation of cardiac function.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Myocytes, Cardiac; Norepinephrine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol-4-Phosphate 3-Kinase; Rats; Rats, Sprague-Dawley | 2014 |
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Cardiovascular Diseases; Disease Models, Animal; Echocardiography; Endothelium, Vascular; Heart Ventricles; Hemodynamics; Hypertension; Imidazoles; Male; Oxidative Stress; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley | 2014 |
Novel role of aminopeptidase-A in angiotensin-(1-7) metabolism post myocardial infarction.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Enzyme Inhibitors; Glutamyl Aminopeptidase; Kinetics; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Tandem Mass Spectrometry; Ventricular Remodeling | 2014 |
Adiponectin expression protects against angiotensin II-mediated inflammation and accelerated atherosclerosis.
Topics: Adiponectin; Angiotensin II; Animals; Apolipoproteins; Atherosclerosis; Blood Pressure; Cholesterol; Disease Models, Animal; Gene Expression; Hypertension; Inflammation; Liver; Macrophages; Male; Mice; Mice, Knockout; Protein Multimerization; Protein Transport; Receptors, Adiponectin; Receptors, LDL; Receptors, Scavenger | 2014 |
Aliskiren limits abdominal aortic aneurysm, ventricular hypertrophy and atherosclerosis in an apolipoprotein-E-deficient mouse model.
Topics: Amides; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Fumarates; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; Mice, Knockout | 2014 |
Effects of a domain-selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Cardiomegaly; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Hypertension; Hypertrophy; Kidney; Lisinopril; Mice; Mice, Transgenic | 2014 |
Obesity induces neuroinflammation mediated by altered expression of the renin-angiotensin system in mouse forebrain nuclei.
Topics: Adiposity; Angiotensin II; Animals; Apoptosis Regulatory Proteins; Basic Helix-Loop-Helix Transcription Factors; Body Mass Index; Calcium-Binding Proteins; Cytokines; Diet, High-Fat; Disease Models, Animal; Encephalitis; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Neuroglia; Obesity; Prosencephalon; Renin-Angiotensin System; Repressor Proteins | 2014 |
Smad7 inhibits AngII-mediated hypertensive nephropathy in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Gene Transfer Techniques; Genetic Therapy; Hypertension, Renal; Immunohistochemistry; Interleukin-1beta; Kidney; Kidney Diseases; Macrophages; Male; Mice; Mice, Inbred Strains; Nephritis; NF-kappa B; Real-Time Polymerase Chain Reaction; Signal Transduction; Smad7 Protein; Tumor Necrosis Factor-alpha | 2014 |
Tenascin C protects aorta from acute dissection in mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Calcium Chloride; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Hemodynamics; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Signal Transduction; Tenascin; Transforming Growth Factor beta | 2014 |
An ongoing role of α-calcitonin gene-related peptide as part of a protective network against hypertension, vascular hypertrophy, and oxidative stress.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Endothelins; Hypertension; Hypertrophy; Mesentery; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Signal Transduction; Vasodilation | 2014 |
Glucocorticoids activate the local renin-angiotensin system in bone: possible mechanism for glucocorticoid-induced osteoporosis.
Topics: Angiotensin II; Animals; Bone and Bones; Dexamethasone; Disease Models, Animal; Glucocorticoids; Male; Osteoporosis; Peptidyl-Dipeptidase A; Rabbits; Renin-Angiotensin System | 2014 |
Inhibition of farnesyl pyrophosphate synthase prevents angiotensin II-induced cardiac fibrosis in vitro.
Topics: Angiotensin II; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Enzyme Activation; Fibroblasts; Fibrosis; Gene Expression; Gene Knockout Techniques; Geranyltranstransferase; Myocardium; Protein Prenylation; Rats; rhoA GTP-Binding Protein; RNA Interference; Transforming Growth Factor beta1 | 2014 |
The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Fibroblasts; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; MicroRNAs; Myeloid Differentiation Factor 88; Oligonucleotides; RNA Interference; RNA, Long Noncoding; Time Factors; Transfection | 2014 |
miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling.
Topics: Angiotensin II; Animals; Disease Models, Animal; Endomyocardial Fibrosis; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Hypertension; Mice; MicroRNAs; Molecular Targeted Therapy; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta | 2014 |
Increasing cGMP-dependent protein kinase activity attenuates unilateral ureteral obstruction-induced renal fibrosis.
Topics: Actins; Angiotensin II; Animals; Cadherins; Cells, Cultured; Culture Media, Conditioned; Cyclic GMP-Dependent Protein Kinase Type I; Cytokines; Disease Models, Animal; Fibrosis; Inflammation Mediators; Kidney Diseases; Kidney Tubules, Proximal; Macrophages; Male; Mice; Mice, Transgenic; Phosphodiesterase 5 Inhibitors; Phosphorylation; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Smad2 Protein; Sulfones; Time Factors; Transforming Growth Factor beta1; Up-Regulation; Ureteral Obstruction | 2014 |
Heterogeneous downregulation of angiotensin II AT1-A and AT1-B receptors in arterioles in STZ-induced diabetic rat kidneys.
Topics: Angiotensin II; Animals; Arterioles; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Kidney; Myocytes, Smooth Muscle; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin | 2014 |
Puerarin inhibits angiotensin II-induced cardiac hypertrophy via the redox-sensitive ERK1/2, p38 and NF-κB pathways.
Topics: Administration, Oral; Angiotensin II; Animals; Antioxidants; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypertrophy, Left Ventricular; Isoflavones; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NF-kappa B; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Reactive Oxygen Species; Signal Transduction; Tetrazoles; Ultrasonography; Valine; Valsartan; Ventricular Remodeling | 2014 |
Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis.
Topics: Angiotensin II; Animals; Bile Ducts; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hepatic Stellate Cells; Humans; Janus Kinase 2; Ligation; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Thioacetamide | 2014 |
Ulinastatin activates the renin-angiotensin system to ameliorate the pathophysiology of severe acute pancreatitis.
Topics: Acute Disease; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Ceruletide; Disease Models, Animal; Gene Expression; Glycoproteins; Lipopolysaccharides; Mice, Inbred C57BL; Molecular Targeted Therapy; Pancreatitis; Peptide Fragments; Peptidyl-Dipeptidase A; Prospective Studies; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Severity of Illness Index | 2014 |
Phosphodiesterase 3A1 protects the heart against angiotensin II-induced cardiac remodeling through regulation of transforming growth factor-β expression.
Topics: Angiotensin II; Animals; Blotting, Western; Cardiomyopathy, Hypertrophic; Cyclic Nucleotide Phosphodiesterases, Type 3; Disease Models, Animal; Echocardiography; Heart Ventricles; Mice; Mice, Transgenic; Transforming Growth Factor beta; Vasoconstrictor Agents; Ventricular Remodeling | 2014 |
Female spontaneously hypertensive rats are more dependent on ANG (1-7) to mediate effects of low-dose AT1 receptor blockade than males.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Adhesion Molecules; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Male; Membrane Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sex Factors; Tetrazoles | 2014 |
Effects of renal denervation on regional hemodynamics and kidney function in experimental hyperdynamic sepsis.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Creatinine; Denervation; Disease Models, Animal; Escherichia coli Infections; Female; Glomerular Filtration Rate; Hemodynamics; Kidney; Norepinephrine; Renal Artery; Renal Circulation; Sepsis; Sheep; Sympathetic Nervous System | 2014 |
CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Brain-Derived Neurotrophic Factor; Central Nervous System; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Hexamethonium; Hypertension; Male; Neuronal Plasticity; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2014 |
Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis.
Topics: Angiotensin II; Animals; Animals, Newborn; Arachidonic Acids; Biomarkers; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Epoxide Hydrolases; Fibrosis; Hypertension; Interleukin-6; Male; Metabolome; Mice; Mice, Inbred C57BL; Myocardium; Myofibroblasts; Ventricular Remodeling | 2014 |
Cardiac hypertrophy is negatively regulated by miR-541.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Male; Mice, Inbred C57BL; Mice, Transgenic; Microphthalmia-Associated Transcription Factor; MicroRNAs; Transcription, Genetic | 2014 |
miR-34a modulates angiotensin II-induced myocardial hypertrophy by direct inhibition of ATG9A expression and autophagic activity.
Topics: Angiotensin II; Animals; Autophagy; Base Sequence; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Membrane Proteins; MicroRNAs; Molecular Sequence Data; Myocardium; Myocytes, Cardiac; Rats, Sprague-Dawley; RNA, Small Interfering; Systole; Vacuoles | 2014 |
COX-2 mediates angiotensin II-induced (pro)renin receptor expression in the rat renal medulla.
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin | 2014 |
Enhanced expression of Gqα and PLC-β1 proteins contributes to vascular smooth muscle cell hypertrophy in SHR: role of endogenous angiotensin II and endothelin-1.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Phospholipase C beta; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; RNA Interference; Signal Transduction; Transcription Factor AP-1; Transfection; Up-Regulation | 2014 |
Angiotensin II in septic shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cell Respiration; Disease Models, Animal; Dose-Response Relationship, Drug; Fluid Therapy; Hemodynamics; Hypotension; Male; Mitochondria; Norepinephrine; Peritonitis; Random Allocation; Renin-Angiotensin System; Shock, Septic; Swine; Vasoconstrictor Agents | 2014 |
Antihypertensive and vascular remodelling effects of the imperatorin derivative OW1 in renovascular hypertension rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Calcitonin Gene-Related Peptide; Collagen Type I; Collagen Type III; Disease Models, Animal; Furocoumarins; Hypertension, Renovascular; Kidney; Male; Mesenteric Arteries; Random Allocation; Rats; Rats, Sprague-Dawley; Renal Artery; Vascular Remodeling; Vasodilator Agents | 2014 |
Endothelial cell-specific reactive oxygen species production increases susceptibility to aortic dissection.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Cyclophilins; Disease Models, Animal; Disease Susceptibility; Endothelium, Vascular; Male; Matrix Metalloproteinases; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Reactive Oxygen Species; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2014 |
Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cytoskeletal Proteins; Disease Models, Animal; DNA-Binding Proteins; LIM Domain Proteins; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Proteins; Mice, Knockout; Phosphoproteins; Reactive Oxygen Species; Signal Transduction | 2014 |
Prevention of abdominal aortic aneurysm by anti-microRNA-712 or anti-microRNA-205 in angiotensin II-infused mice.
Topics: Adult; Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Case-Control Studies; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Gene Expression Profiling; GPI-Linked Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Middle Aged; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Time Factors; Tissue Inhibitor of Metalloproteinase-3; Up-Regulation | 2014 |
Calcitriol supplementation improves endothelium-dependent vasodilation in rat hypertensive renal injury.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Calcitriol; Dietary Supplements; Dinoprost; Disease Models, Animal; Endothelium, Vascular; Glucuronidase; Hypertension; Irbesartan; Kidney; Kidney Diseases; Klotho Proteins; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Tetrazoles; Vasodilation; Vitamins | 2014 |
A comparison of the efficacy of surgical renal denervation and pharmacologic therapies in post-myocardial infarction heart failure.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Denervation; Disease Models, Animal; Endothelins; Heart Failure; Heart Rate; Hemodynamics; Kidney; Male; Myocardial Infarction; Natriuretic Peptide, Brain; Norepinephrine; Rats; Rats, Wistar; Renin; Treatment Outcome; Ventricular Function, Left | 2014 |
Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cellulase; Diet, Mediterranean; Disease Models, Animal; Epoxide Hydrolases; Fatty Acids; Gene Knock-In Techniques; Hypertension; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitrates; Nitrites; Sulfhydryl Compounds; Vasoconstrictor Agents; Vasodilation | 2014 |
CXCR6 plays a critical role in angiotensin II-induced renal injury and fibrosis.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Bone Marrow Transplantation; Cytokines; Disease Models, Animal; Fibrosis; Green Fluorescent Proteins; Hypertension; Inflammation Mediators; Kidney; Kidney Diseases; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myofibroblasts; Receptors, CXCR; Receptors, CXCR6; Signal Transduction; T-Lymphocytes; Time Factors | 2014 |
Gestational exposure to elevated testosterone levels induces hypertension via heightened vascular angiotensin II type 1 receptor signaling in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Female; Hypertension, Pregnancy-Induced; Losartan; Mesenteric Arteries; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Testosterone | 2014 |
Estrogen regulation of the brain renin-angiotensin system in protection against angiotensin II-induced sensitization of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Brain; Disease Models, Animal; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression Regulation; Hypertension; Infusions, Intraventricular; Male; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger; Sex Factors; Telemetry; Time Factors | 2014 |
A method for noninvasive longitudinal measurements of [Ca2+] in arterioles of hypertensive optical biosensor mice.
Topics: Angiotensin II; Animals; Arterial Pressure; Arterioles; Biosensing Techniques; Calcium; Calcium Signaling; Disease Models, Animal; Fluorescence Resonance Energy Transfer; Hypertension; Mice; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Skin; Sodium Chloride, Dietary; Time Factors | 2014 |
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart Failure; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Indoles; Male; Mice; Mice, Knockout; Muscle, Skeletal; Muscular Atrophy; Myocardium; Signal Transduction; Stroke Volume; Systole; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2014 |
Class A scavenger receptor deficiency augments angiotensin II-induced vascular remodeling.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Vessels; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Coculture Techniques; Crosses, Genetic; Disease Models, Animal; Hypertension; Infusions, Intravenous; Macrophages; Male; Mice; Mice, 129 Strain; Mice, Inbred ICR; Mice, Knockout; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Scavenger Receptors, Class A; Transplantation Chimera | 2014 |
Administration of angiotensin II and a bradykinin B2 receptor blocker in midpregnancy impairs gestational outcome in guinea pigs.
Topics: Angiotensin II; Animals; Bradykinin B2 Receptor Antagonists; Disease Models, Animal; Feasibility Studies; Female; Fetal Development; Guinea Pigs; Infusions, Subcutaneous; Kallikrein-Kinin System; Kidney; Organ Size; Placenta; Placentation; Pre-Eclampsia; Pregnancy; Pregnancy Maintenance; Pyrrolidines; Receptor, Bradykinin B2; Renin-Angiotensin System; Thiosemicarbazones; Uterus; Vascular Remodeling | 2014 |
Humid heat exposure induced oxidative stress and apoptosis in cardiomyocytes through the angiotensin II signaling pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Female; Heat Stress Disorders; HEK293 Cells; Hot Temperature; Humans; Humidity; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction; Time Factors; Valsartan | 2015 |
Salvianolic acid A, a matrix metalloproteinase-9 inhibitor of Salvia miltiorrhiza, attenuates aortic aneurysm formation in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Lactates; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Knockout; Salvia miltiorrhiza | 2014 |
Sex-specific T-cell regulation of angiotensin II-dependent hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Female; Heart Rate; Homeodomain Proteins; Hypertension; Interleukin-10; Interleukin-17; Male; Mice; Mice, Knockout; Sex Factors; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2014 |
Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis.
Topics: Amidohydrolases; Angiotensin II; Animals; Arachidonic Acids; Benzamides; Benzodioxoles; Blood Pressure; Carbamates; Disease Models, Animal; Endocannabinoids; Female; Glycerides; Humans; Hydrolysis; Hypertension, Pregnancy-Induced; Male; Monoglycerides; Piperidines; Polyunsaturated Alkamides; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Uterine Artery; Vasoconstriction | 2014 |
[Protective effect of acupuncture on heart in mice with hyperlipemia and its mechanism].
Topics: Acupuncture Points; Acupuncture Therapy; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Heart; Heart Diseases; Humans; Hyperlipidemias; Male; Mice; Mice, Inbred C57BL; Myocardium | 2014 |
Exogenous administration of thiosulfate, a donor of hydrogen sulfide, attenuates angiotensin II-induced hypertensive heart disease in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hydrogen Sulfide; Hypertension; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sulfides; Thiosulfates | 2015 |
AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.
Topics: A Kinase Anchor Proteins; Angiotensin II; Animals; Calcium Signaling; Disease Models, Animal; Endothelium, Vascular; Hypertension; Ion Channel Gating; Mice; Mice, Knockout; TRPV Cation Channels; Vasoconstrictor Agents; Vasodilation | 2014 |
Angiotensin II induces region-specific medial disruption during evolution of ascending aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Tunica Media | 2014 |
Renal sympathetic denervation suppresses ventricular substrate remodelling in a canine high-rate pacing model.
Topics: Aldosterone; Angiotensin II; Animals; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Catheter Ablation; Disease Models, Animal; Disease Progression; Dogs; Female; Fibrosis; Heart Failure; Heart Ventricles; Kidney; Male; Natriuretic Peptide, Brain; Sympathectomy; Time Factors; Transforming Growth Factor beta; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2014 |
Murine pressure overload models: a 30-MHz look brings a whole new "sound" into data interpretation.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cardiomegaly; Constriction, Pathologic; Data Interpretation, Statistical; Disease Models, Animal; Echocardiography; Echocardiography, Doppler; Mice; Mice, Inbred C57BL; Pressure; Vasoconstrictor Agents | 2014 |
Osteopontin-CD44v6 interaction mediates calcium deposition via phospho-Akt in valve interstitial cells from patients with noncalcified aortic valve sclerosis.
Topics: Angiotensin II; Animals; Aortic Valve; Aortic Valve Stenosis; Bioreactors; Bone Morphogenetic Protein 4; Calcinosis; Calcium; Cell Transdifferentiation; Disease Models, Animal; Disease Progression; Humans; Hyaluronan Receptors; Male; Mice; Mice, Inbred C57BL; Osteogenesis; Osteopontin; Phosphorylation; Protein Interaction Mapping; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Signal Transduction | 2014 |
Differences in cell-type-specific responses to angiotensin II explain cardiac remodeling differences in C57BL/6 mouse substrains.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Fibrosis; Galectin 3; Heart; Heart Ventricles; Hypertrophy, Left Ventricular; In Vitro Techniques; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocardium; Osteopontin; Ventricular Remodeling | 2014 |
Mechanisms of renal control of potassium homeostasis in complete aldosterone deficiency.
Topics: Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Disease Models, Animal; Epithelial Sodium Channels; Homeostasis; Hypoaldosteronism; Kidney; Male; Mice; Mice, Knockout; Potassium; Potassium Channels; Potassium, Dietary | 2015 |
Oxidative status in the macula densa modulates tubuloglomerular feedback responsiveness in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney Glomerulus; Kidney Tubules; Mice, Inbred C57BL; Nephrons; Nitric Oxide; Oxidative Stress; Vasoconstrictor Agents | 2015 |
Hydrogen sulfide treatment reduces blood pressure and oxidative stress in angiotensin II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cystathionine gamma-Lyase; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Hydrogen Sulfide; Hypertension; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Superoxides | 2015 |
Effect of angiotensin II and small GTPase Ras signaling pathway inhibition on early renal changes in a murine model of obstructive nephropathy.
Topics: Angiotensin II; Animals; Atorvastatin; Disease Models, Animal; Fibrosis; Heptanoic Acids; Humans; Kidney; Kidney Diseases; Mice; Monomeric GTP-Binding Proteins; Pyrroles; Receptor, Angiotensin, Type 1; Signal Transduction; Ureteral Obstruction | 2014 |
[Effect of compound qingqin liquid on the expression levels of ang II and COX-2 mRNA transcription and protein expression in the renal tissue of uric acid nephropathy rats: an experimental study].
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Disease Models, Animal; Drugs, Chinese Herbal; Kidney; Kidney Diseases; Male; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Uric Acid | 2014 |
The effect of baicalin in a mouse model of retinopathy of prematurity.
Topics: Angiotensin II; Animals; Disease Models, Animal; Down-Regulation; Flavonoids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Retinopathy of Prematurity; Vascular Endothelial Growth Factor A | 2015 |
Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Atrial Remodeling; B-Cell CLL-Lymphoma 10 Protein; Cell Adhesion; Cell Movement; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Heart Diseases; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Myocardium; NF-kappa B | 2014 |
Tumor necrosis factor-α produced in the kidney contributes to angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Renal Insufficiency, Chronic; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2014 |
NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice.
Topics: Angiotensin II; Animals; Antibodies; Aortic Aneurysm, Abdominal; Disease Models, Animal; Interleukin-1beta; Macrophages; Matrix Metalloproteinase 12; Matrix Metalloproteinase 9; Membrane Glycoproteins; Mice; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Reactive Oxygen Species | 2014 |
Combined suppression of the intrarenal and circulating vasoconstrictor renin-ACE-ANG II axis and augmentation of the vasodilator ACE2-ANG 1-7-Mas axis attenuates the systemic hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Topics: Age Factors; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Hypoxia; Kidney; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation | 2015 |
Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation | 2015 |
Elimination of vitamin D receptor in vascular endothelial cells alters vascular function.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Blotting, Western; Disease Models, Animal; DNA; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Humans; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Natriuretic Peptide, Brain; Rats; Receptors, Calcitriol; Vasodilation | 2014 |
The renin-angiotensin system mediates EGF receptor-vitamin d receptor cross-talk in colitis-associated colon cancer.
Topics: Angiotensin II; Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colitis; Colonic Neoplasms; Disease Models, Animal; ErbB Receptors; Female; Humans; Macrophages; Mice; Mice, Knockout; Proto-Oncogene Proteins p21(ras); Receptor Cross-Talk; Receptors, Calcitriol; Renin-Angiotensin System; Signal Transduction; Snail Family Transcription Factors; Transcription Factors | 2014 |
Reduced plasma angiotensin II levels are reversed by hydroxyurea treatment in mice with sickle cell disease.
Topics: Anemia, Sickle Cell; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hydroxyurea; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2014 |
[Protective effect of an angiotensin-converting-enzyme inhibitor on neurogenic pulmonary edema in rabbits].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Enalaprilat; Female; Fibrinogen; Gene Expression Regulation, Enzymologic; Lung; Male; Peptidyl-Dipeptidase A; Pulmonary Edema; Rabbits; Random Allocation; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2014 |
Angiotensin II mediates angiotensin converting enzyme type 2 internalization and degradation through an angiotensin II type I receptor-dependent mechanism.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1 | 2014 |
Inhibiting the Th17/IL-17A-related inflammatory responses with digoxin confers protection against experimental abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cardiotonic Agents; Digoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Receptor Subfamily 1, Group F, Member 3; Pancreatic Elastase; Survival Rate; Swine; Th17 Cells | 2014 |
IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
Topics: Aging; Angiotensin II; Animals; Biomarkers; Blood-Brain Barrier; Cerebrovascular Circulation; Dementia; Disease Models, Animal; Encephalitis; Hippocampus; Homeostasis; Hypertension; Insulin-Like Growth Factor I; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Microglia; Middle Cerebral Artery; TRPC Cation Channels; Vasoconstrictor Agents | 2014 |
Oligoclonal CD8+ T cells play a critical role in the development of hypertension.
Topics: Adaptive Immunity; Angiotensin II; Animals; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; CD8-Positive T-Lymphocytes; Disease Models, Animal; Endothelium, Vascular; Homeodomain Proteins; Hypertension; Kidney; Major Histocompatibility Complex; Male; Mice; Mice, Knockout; Oligoclonal Bands; Vascular Remodeling | 2014 |
Chronic central nervous system MC3/4R blockade attenuates hypertension induced by nitric oxide synthase inhibition but not by angiotensin II infusion.
Topics: Angiotensin II; Animals; Blood Pressure; Central Nervous System; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Infusions, Intravenous; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4 | 2015 |
Mesenchymal Stem Cells Overexpressing Angiotensin-Converting Enzyme 2 Rescue Lipopolysaccharide-Induced Lung Injury.
Topics: Acute Lung Injury; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Bone Marrow Cells; Cells, Cultured; Disease Models, Animal; HEK293 Cells; Humans; Lipopolysaccharides; Lung; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Permeability; Spectroscopy, Near-Infrared; Spleen | 2015 |
The angiotensin-(1-7)/Mas axis reduces myonuclear apoptosis during recovery from angiotensin II-induced skeletal muscle atrophy in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Disease Models, Animal; Immunoblotting; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Atrophy; Peptide Fragments; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2015 |
Changes in levels of angiotensin II and its receptors in a model of inverted stress-induced cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomyopathies; Disease Models, Animal; Female; Myocardium; Peptide Fragments; Rabbits; Receptors, Angiotensin; Renin-Angiotensin System; Stress, Physiological | 2014 |
Serelaxin reduces oxidative stress and asymmetric dimethylarginine in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Arginine; Arterial Pressure; Dinoprost; Disease Models, Animal; Down-Regulation; Humans; Hypertension; Injections, Subcutaneous; Kidney; Liver; Male; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Proteinuria; Rats, Sprague-Dawley; Recombinant Proteins; Relaxin; Thiobarbituric Acid Reactive Substances | 2014 |
Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aortic Aneurysm, Abdominal; Diminazene; Disease Models, Animal; Enzyme Activation; Female; Humans; Hypercholesterolemia; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Peptidyl-Dipeptidase A; Receptors, LDL; Renin-Angiotensin System; RNA, Messenger | 2014 |
Osteoprotegerin deficiency limits angiotensin II-induced aortic dilatation and rupture in the apolipoprotein E-knockout mouse.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Blood Pressure; Cathepsins; Dilatation, Pathologic; Disease Models, Animal; Humans; Inflammation Mediators; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Osteoprotegerin; Pancreatic Elastase; Proteolysis | 2014 |
Direct pro-inflammatory effects of prorenin on microglia.
Topics: Angiotensin II; Animals; Brain; Cell Line; Cells, Cultured; Cytokines; Disease Models, Animal; Gene Expression; Humans; Hypertension; Inflammation Mediators; Male; Mice; Mice, Transgenic; Microglia; Minocycline; NF-kappa B; ras Proteins; Rats; Rats, Inbred SHR; Renin | 2014 |
5-Lipoxygenase pathway in experimental abdominal aortic aneurysms.
Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Arachidonate 5-Lipoxygenase; Bone Marrow Transplantation; Disease Models, Animal; Disease Progression; Humans; Hypercholesterolemia; Lipoxygenase Inhibitors; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Neutrophil Infiltration; Pancreatic Elastase; Receptors, LDL; Signal Transduction; Transplantation Chimera | 2014 |
[Protective effects and mechanism of congguiyishen capsules on diabetic nephropathy rats].
Topics: Angiotensin II; Animals; Blood Glucose; Capsules; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Female; Hypoglycemic Agents; Kidney; Male; Plants, Medicinal; Proteinuria; Random Allocation; Rats; Rats, Sprague-Dawley; Streptozocin | 2014 |
Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model.
Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Differentiation; Cells, Cultured; Collagen; Dipeptides; Disease Models, Animal; Disease Progression; Elastin; Gene Expression Regulation; Humans; Macrophages; Male; Matrix Metalloproteinases; Mice, Knockout; Middle Aged; Receptor, Notch1; Signal Transduction; Time Factors; Transforming Growth Factor beta2 | 2014 |
GABA(A) receptor overexpression in the lateral hypothalamic area attenuates gastric ischemia‑reperfusion injury in rats.
Topics: Adenoviridae; Angiotensin II; Animals; Blood Flow Velocity; Disease Models, Animal; Gastric Mucosa; Genetic Vectors; Hypothalamic Area, Lateral; Immunohistochemistry; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reperfusion Injury; Splanchnic Nerves; Stomach | 2015 |
Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
Topics: Angiotensin II; Animals; Binding Sites; CCCTC-Binding Factor; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; DNA Methylation; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Male; Mice, Inbred C57BL; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; S-Adenosylmethionine; Sp1 Transcription Factor; Telomerase; Telomere; Telomere Shortening; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2015 |
Baicalein attenuates angiotensin II-induced cardiac remodeling via inhibition of AKT/mTOR, ERK1/2, NF-κB, and calcineurin signaling pathways in mice.
Topics: Angiotensin II; Animals; Calcineurin Inhibitors; Cytokines; Disease Models, Animal; Enzyme Activation; Fibrosis; Flavanones; Gene Expression Regulation; Hypertension; Hypertrophy, Left Ventricular; Inflammation Mediators; Lipoxygenase Inhibitors; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; NF-kappa B; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Ventricular Function, Left; Ventricular Remodeling | 2015 |
Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.
Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Cells, Cultured; Disease Models, Animal; Female; Fibrosis; Humans; Inflammasomes; Inflammation Mediators; Interleukin-1beta; Macrophage Activation; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Time Factors | 2015 |
Electroacupuncture improves cerebral blood flow and attenuates moderate ischemic injury via Angiotensin II its receptors-mediated mechanism in rats.
Topics: Angiotensin II; Animals; Brain Ischemia; Cerebral Infarction; Cerebrum; Disease Models, Animal; Electroacupuncture; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Wistar; Receptors, Angiotensin; Regional Blood Flow; Up-Regulation | 2014 |
Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms.
Topics: Aneurysm; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Arterial Pressure; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Elastin; Gene Deletion; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Male; Matrix Metalloproteinase 2; Mesenteric Artery, Superior; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Norepinephrine; Receptors, LDL; RNA, Messenger; Tumor Suppressor Proteins; Urokinase-Type Plasminogen Activator | 2015 |
Benefical therapeutic effect of Chinese Herbal Xinji'erkang formula on hypertension-induced renal injury in the 2-kidney-1-clip hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Kidney; Kidney Diseases; Magnoliopsida; Male; Organ Size; Phytotherapy; Rats, Sprague-Dawley; Renal Artery; Surgical Instruments; Transforming Growth Factor beta1 | 2014 |
Arrest of progression of pre-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by low level laser phototherapy.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Lasers, Semiconductor; Low-Level Light Therapy; Mice; Mice, Inbred C57BL | 2014 |
Pentoxifylline alleviates hypertension in metabolic syndrome: effect on low-grade inflammation and angiotensin system.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Inflammation; Male; Metabolic Syndrome; Pentoxifylline; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Vasodilator Agents | 2015 |
Preventive effect of gomisin J from Schisandra chinensis on angiotensin II-induced hypertension via an increased nitric oxide bioavailability.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biological Availability; Blood Pressure; Cyclooctanes; Dioxoles; Disease Models, Animal; Hypertension; Lignans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Plant Extracts; Polycyclic Compounds; Reactive Oxygen Species; Schisandra; Treatment Outcome; Vasodilator Agents | 2015 |
Endothelial MRTF-A mediates angiotensin II induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Line; Disease Models, Animal; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Epigenesis, Genetic; Fibrosis; Gene Expression Regulation; Humans; Mice; Models, Biological; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Trans-Activators; Transcriptional Activation | 2015 |
Bone marrow from blotchy mice is dispensable to regulate blood copper and aortic pathologies but required for inflammatory mediator production in LDLR-deficient mice during chronic angiotensin II infusion.
Topics: Adenosine Triphosphatases; Angiotensin II; Animals; Aortic Aneurysm; Aortic Rupture; Biomarkers; Bone Marrow; Bone Marrow Transplantation; Cardiovascular Agents; Cation Transport Proteins; Copper; Copper-Transporting ATPases; Cytokines; Disease Models, Animal; Enzymes; Female; Lipids; Male; Mice; Mice, Inbred Strains; Receptors, LDL | 2015 |
Trimethylamine-N-oxide: a carnitine-derived metabolite that prolongs the hypertensive effect of angiotensin II in rats.
Topics: Angiotensin II; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Hypertension; Male; Methylamines; Oxidants; Rats; Rats, Sprague-Dawley | 2014 |
Sirtuin-6 inhibits cardiac fibroblasts differentiation into myofibroblasts via inactivation of nuclear factor κB signaling.
Topics: Angiotensin II; Animals; Cell Differentiation; Cell Proliferation; Constriction, Pathologic; Disease Models, Animal; Extracellular Matrix; Fibrosis; Focal Adhesions; Gene Silencing; Male; Myocardium; Myofibroblasts; NF-kappa B; Rats, Sprague-Dawley; Signal Transduction; Sirtuins; Transcription, Genetic; Up-Regulation | 2015 |
Hemodynamic basis for the limited renal injury in rats with angiotensin II-induced hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hemodynamics; Hypertension; Kidney; Male; Rats, Sprague-Dawley; Renal Circulation | 2015 |
Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling | 2015 |
A peptide antagonist of thrombospondin-1 promotes abdominal aortic aneurysm progression in the angiotensin II-infused apolipoprotein-E-deficient mouse.
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cytokines; Disease Models, Animal; Disease Progression; Elastin; Inflammation Mediators; Injections, Intraperitoneal; Male; Mice, Knockout; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Smad2 Protein; Smad3 Protein; Thrombospondin 1; Time Factors; Transforming Growth Factor beta1 | 2015 |
Angiotensin II mobilizes spleen monocytes to promote the development of abdominal aortic aneurysm in Apoe-/- mice.
Topics: Angiotensin II; Animals; Antigens, Ly; Aortic Aneurysm, Abdominal; Apolipoproteins E; B-Lymphocytes; Bone Marrow Transplantation; Cell Movement; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Hypercholesterolemia; Male; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Spleen; Splenectomy; Time Factors | 2015 |
Angiotensin II-mediated GFR decline in subtotal nephrectomy is due to acid retention associated with reduced GFR.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Disease Models, Animal; Female; Glomerular Filtration Rate; Kidney; Male; Microdialysis; Nephrectomy; Protons; Rats; Rats, Wistar; Sodium Bicarbonate; Tetrazoles; Valine; Valsartan | 2015 |
Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Cells, Cultured; Cytoprotection; Disease Models, Animal; Endoplasmic Reticulum Stress; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Matrix; Humans; Interleukin-6; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Protein Kinase Inhibitors; Quinazolines; Rats, Sprague-Dawley; Time Factors | 2015 |
Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation.
Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Dissection; Contrast Media; Dilatation, Pathologic; Disease Models, Animal; Male; Mice, Inbred C57BL | 2015 |
Imaging vessel wall biology to predict outcome in abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Aortography; Biomarkers; Disease Models, Animal; Disease Progression; Enzyme Activation; Feasibility Studies; Male; Matrix Metalloproteinases; Mice, Inbred C57BL; Mice, Transgenic; Molecular Imaging; Multimodal Imaging; Predictive Value of Tests; Radiopharmaceuticals; Risk Assessment; Risk Factors; Time Factors; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2015 |
Genetic knockdown of estrogen receptor-alpha in the subfornical organ augments ANG II-induced hypertension in female mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Estrogen Receptor alpha; Female; Ganglionic Blockers; Gene Knockdown Techniques; Genotype; Heart Rate; Hypertension; Male; Mice, Knockout; Nestin; Phenotype; Subfornical Organ; Sympathetic Nervous System | 2015 |
Esophagoprotective activity of angiotensin-(1-7) in experimental model of acute reflux esophagitis. Evidence for the role of nitric oxide, sensory nerves, hypoxia-inducible factor-1alpha and proinflammatory cytokines.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclooxygenase 2; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-1beta; Male; Mucous Membrane; Nitric Oxide; Peptide Fragments; Protective Agents; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Wistar; Receptors, G-Protein-Coupled; Regional Blood Flow; RNA, Messenger; Sensory Receptor Cells; Tumor Necrosis Factor-alpha | 2014 |
Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.
Topics: Acute Disease; Adventitia; Aged; Aminopropionitrile; Angiotensin II; Animals; Antibodies, Monoclonal; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic Rupture; Aortography; Chemokine CXCL1; Chemokine CXCL12; Chemotaxis, Leukocyte; Dilatation, Pathologic; Disease Models, Animal; Female; Granulocyte Colony-Stimulating Factor; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Neutrophil Activation; Neutrophil Infiltration; Neutrophils; Receptors, Interleukin-8B; Signal Transduction; Time Factors | 2015 |
Angiotensin II as a morphogenic cytokine stimulating fibrogenesis of human tenon's capsule fibroblasts.
Topics: Angiotensin II; Animals; Aqueous Humor; Blotting, Western; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gene Expression Regulation; Glaucoma; Immunohistochemistry; Rabbits; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tenon Capsule; Trabeculectomy; Wound Healing | 2015 |
Deficiency of endothelium-specific transcription factor Sox17 induces intracranial aneurysm.
Topics: Adult; Aged; Angiotensin II; Animals; Aorta; Cells, Cultured; Cerebral Arteries; Cyclin-Dependent Kinase Inhibitor Proteins; Dilatation, Pathologic; Disease Models, Animal; Endothelium, Vascular; Female; HMGB Proteins; Humans; Hypertension; Intracranial Aneurysm; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myocytes, Smooth Muscle; Paracrine Communication; RNA Interference; SOXF Transcription Factors; Specific Pathogen-Free Organisms; Subarachnoid Hemorrhage; Transcription, Genetic; Up-Regulation; Veins | 2015 |
Foxp3+ regulatory T cells play a protective role in angiotensin II-induced aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Flow Cytometry; Forkhead Transcription Factors; Immunity, Cellular; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory | 2015 |
Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice.
Topics: Angiotensin II; Animals; Biological Transport; Blood Pressure; Disease Models, Animal; Epithelial Sodium Channels; Genotype; Hypertension; Interferon-gamma; Interleukin-17; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL; Mice, Knockout; Sodium; Sodium Chloride Symporters; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Solute Carrier Family 12, Member 1 | 2015 |
Nox4 is a major source of superoxide production in human brain pericytes.
Topics: Angiotensin II; Animals; Brain; Cell Hypoxia; Cell Membrane; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Humans; Infarction, Middle Cerebral Artery; Male; Mice; Microvessels; NADPH Oxidase 4; NADPH Oxidases; Pericytes; Receptors, Angiotensin; RNA Interference; Superoxides; Time Factors; Transfection | 2014 |
Gene expression profile in the early stage of angiotensin II-induced cardiac remodeling: a time series microarray study in a mouse model.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Myocardium; Oligonucleotide Array Sequence Analysis; Serpin E2; Time Factors | 2015 |
SIRT1 functions as an important regulator of estrogen-mediated cardiomyocyte protection in angiotensin II-induced heart hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Estradiol; Female; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1 | 2014 |
Cardiomyocyte-specific expression of CYP2J2 prevents development of cardiac remodelling induced by angiotensin II.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Animals; Cells, Cultured; Coculture Techniques; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Disease Models, Animal; Hypertrophy, Left Ventricular; Male; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Cardiac; Oxidative Stress; PPAR gamma; Rats; Signal Transduction; Transcription Factor RelA; Ventricular Function, Left; Ventricular Remodeling | 2015 |
PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension.
Topics: Amiloride; Angiotensin II; Animals; Arteries; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Epithelial Sodium Channels; Female; Hypertension; Kidney; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Proprotein Convertase 9; Proprotein Convertases; Serine Endopeptidases; Sodium; Sodium Chloride, Dietary | 2015 |
Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bexarotene; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Rosuvastatin Calcium; Signal Transduction; Tetrahydronaphthalenes | 2015 |
Divergent roles of matrix metalloproteinase 2 in pathogenesis of thoracic aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Calcium Chloride; Cells, Cultured; Collagen; Dilatation, Pathologic; Disease Models, Animal; Elastin; Genotype; Male; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Ultrasonography; Vascular Remodeling | 2015 |
Protective effects of diltiazem against vascular endothelial cell injury induced by angiotensin-II and hypoxia.
Topics: Angiotensin II; Animals; Apoptosis; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cytoprotection; Diltiazem; Disease Models, Animal; Endothelial Cells; Endothelin-1; Humans; Hypoxia; Male; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Wistar; Vascular Diseases | 2015 |
Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology.
Topics: Angiotensin II; Animals; Blood Pressure; Cytosol; Disease Models, Animal; Gene Expression Regulation; Group IV Phospholipases A2; Hypertension; Lipid Metabolism; Mice; Mice, Inbred BALB C; Myocardium; Oxidative Stress; Real-Time Polymerase Chain Reaction; RNA | 2015 |
Angiotensin II type 2-receptor: new clinically validated target in the treatment of neuropathic pain.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Benzhydryl Compounds; Disease Models, Animal; Humans; Isoquinolines; Models, Neurological; Molecular Targeted Therapy; Neuralgia; Receptor, Angiotensin, Type 2; Reproducibility of Results | 2015 |
Unilateral ureteral obstruction attenuates intrarenal angiotensin II generation induced by podocyte injury.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antibodies, Monoclonal; Disease Models, Animal; Down-Regulation; Exotoxins; Female; Glomerular Filtration Rate; Humans; Interleukin-2 Receptor alpha Subunit; Kidney Diseases; Mice, Inbred C57BL; Mice, Transgenic; Podocytes; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Time Factors; Ureteral Obstruction | 2015 |
ApoB-100-related peptide vaccine protects against angiotensin II-induced aortic aneurysm formation and rupture.
Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoprotein B-100; Disease Models, Animal; Immunity, Cellular; Macrophages; Male; Mice; Mice, Knockout; T-Lymphocytes; Vaccines | 2015 |
Activation of the renin-angiotensin system stimulates biliary hyperplasia during cholestasis induced by extrahepatic bile duct ligation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bile Ducts, Extrahepatic; Cell Line; Cell Proliferation; Cholestasis, Extrahepatic; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hyperplasia; Ligation; Losartan; Male; Rats, Inbred F344; Renin-Angiotensin System; Signal Transduction | 2015 |
Valsartan Attenuates Atherosclerosis via Upregulating the Th2 Immune Response in Prolonged Angiotensin II-Treated ApoE(-/-) Mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies, Monoclonal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Disease Models, Animal; Inflammation; Interleukin-5; Lipids; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; T-Lymphocyte Subsets; Th2 Cells; Valsartan | 2015 |
[Up-regulation of intrarenal renin-angiotensin system contributes to renal damage in high-salt induced hypertension rats].
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Male; Proteinuria; Rats; Rats, Inbred WKY; Real-Time Polymerase Chain Reaction; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Up-Regulation | 2015 |
Cys18-Cys137 disulfide bond in mouse angiotensinogen does not affect AngII-dependent functions in vivo.
Topics: Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Blood Pressure; Disease Models, Animal; DNA; DNA Mutational Analysis; Mice; Mutation; Renin; Renin-Angiotensin System | 2015 |
Disruption of the cytochrome P-450 1B1 gene exacerbates renal dysfunction and damage associated with angiotensin II-induced hypertension in female mice.
Topics: Angiotensin II; Animals; Catalase; Cytochrome P-450 CYP1B1; Disease Models, Animal; Drinking; Estradiol; Female; Fibrosis; Genotype; Hypertension; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Natriuresis; Oxidative Stress; Phenotype; Renin-Angiotensin System; Sex Factors; Superoxide Dismutase; Superoxides; Tyrosine; Urination | 2015 |
Angiotensin processing activities in the venom of Thalassophryne nattereri.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Batrachoidiformes; Bradykinin; Brazil; Chromatography, High Pressure Liquid; Disease Models, Animal; Fish Venoms; Fishes, Poisonous; Mice | 2015 |
Investigation of changes in apelin receptor mRNA and protein expression in the myocardium and aorta of rats with two-kidney, one-clip (2K1C) Goldblatt hypertension.
Topics: Angiotensin II; Animals; Aorta; Apelin; Apelin Receptors; Blood Pressure; Disease Models, Animal; Heart Failure; Heart Ventricles; Hypertension, Renovascular; Intercellular Signaling Peptides and Proteins; Kidney; Male; Myocardium; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Surgical Instruments | 2015 |
A crosstalk between chromatin remodeling and histone H3K4 methyltransferase complexes in endothelial cells regulates angiotensin II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Line, Transformed; Chromatin Assembly and Disassembly; Disease Models, Animal; DNA Helicases; Endothelial Cells; Endothelin-1; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Male; Mice; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Signal Transduction; Trans-Activators; Transcription Factors | 2015 |
ACE2 and Ang-(1-7) protect endothelial cell function and prevent early atherosclerosis by inhibiting inflammatory response.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Atherosclerosis; Cell Adhesion; Cell Movement; Chemokine CCL2; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Gene Transfer Techniques; Humans; In Vitro Techniques; Inflammation; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2015 |
Epidermal growth factor receptor is critical for angiotensin II-mediated hypertrophy in cerebral arterioles.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; ErbB Receptors; Female; Gene Expression Regulation; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; RNA; Signal Transduction; Vascular Remodeling | 2015 |
Overexpression of ANO1/TMEM16A, an arterial Ca2+-activated Cl- channel, contributes to spontaneous hypertension.
Topics: Angiotensin II; Animals; Anoctamin-1; Arteries; Blood Pressure; Cell Proliferation; Chloride Channels; Disease Models, Animal; Excitation Contraction Coupling; Gene Expression; Gene Knockdown Techniques; Glycosylation; Male; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Signal Transduction | 2015 |
The role of mAKAPβ in the process of cardiomyocyte hypertrophy induced by angiotensin II.
Topics: A Kinase Anchor Proteins; Angiotensin II; Animals; Biomarkers; Cardiomegaly; Disease Models, Animal; Gene Expression; Hypertrophy; Male; Mitogen-Activated Protein Kinase 1; Myocytes, Cardiac; Rats; RNA Interference; RNA, Small Interfering | 2015 |
Deficiency of Endogenous Acute-Phase Serum Amyloid A Protects apoE-/- Mice From Angiotensin II-Induced Abdominal Aortic Aneurysm Formation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Disease Models, Animal; Elastin; Macrophages; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Random Allocation; Sensitivity and Specificity; Serum Amyloid A Protein | 2015 |
Involvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT2R agonist effectively attenuates growth of PDAC grafts in mice.
Topics: Angiotensin II; Animals; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Gene Expression; Humans; Immunohistochemistry; Mice; Pancreatic Neoplasms; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Transplantation, Isogeneic; Tumor Burden; Tumor Stem Cell Assay | 2015 |
Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Captopril; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Gene Expression Regulation; Hypertension, Renal; Kidney Cortex; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Random Allocation; Rats, Wistar; Renin; RNA, Messenger | 2015 |
ApoA-I/HDL-C levels are inversely associated with abdominal aortic aneurysm progression.
Topics: Aged; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoprotein A-I; Apolipoproteins E; Biomarkers; Cholesterol, HDL; Chromatography, Liquid; Denmark; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Humans; Linear Models; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Multivariate Analysis; Nanotechnology; Peptides; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Proteomics; Registries; Spain; Tandem Mass Spectrometry | 2015 |
Renal tubule angiotensin II type 1 receptor-associated protein promotes natriuresis and inhibits salt-sensitive blood pressure elevation.
Topics: Adaptor Proteins, Signal Transducing; Amiloride; Angiotensin II; Animals; Biomarkers; Blood Pressure; Cell Membrane; Disease Models, Animal; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Hypertension; Kidney Tubules, Distal; Mice, Inbred C57BL; Mice, Transgenic; Natriuresis; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2015 |
Amelioration of Atherosclerosis by the New Medicinal Mushroom Grifola gargal Singer.
Topics: Agaricales; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Biological Products; Blood Vessels; Chemokine CCL2; Chemokine CXCL12; Disease Models, Animal; Fibroblasts; Granulocytes; Grifola; Heart; Injections, Intraperitoneal; Mice; T-Lymphocytes, Regulatory; Transforming Growth Factor beta1; Treatment Outcome; Vascular Endothelial Growth Factor A | 2015 |
Pregnant rats treated with a high-fat/prooxidant Western diet with ANG II and TNF-α are resistant to elevations in blood pressure and renal oxidative stress.
Topics: Angiotensin II; Animals; Antioxidants; Aorta; Arterial Pressure; Birth Weight; Diet, High-Fat; Diet, Western; Disease Models, Animal; Female; Hypertension; Kidney Cortex; Litter Size; Nitric Oxide; Oxidative Stress; Pregnancy; Rats, Sprague-Dawley; Telemetry; Time Factors; Tumor Necrosis Factor-alpha | 2015 |
Histone Methyltransferase SET1 Mediates Angiotensin II-Induced Endothelin-1 Transcription and Cardiac Hypertrophy in Mice.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Endothelin-1; Epigenomics; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Mice; Myocytes, Cardiac | 2015 |
An animal-specific FSI model of the abdominal aorta in anesthetized mice.
Topics: Anesthesia; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Knockout; Models, Cardiovascular | 2015 |
Effect of angiotensin II on voltage-gated sodium currents in aortic baroreceptor neurons and arterial baroreflex sensitivity in heart failure rats.
Topics: Angiotensin II; Animals; Aorta; Arteries; Baroreflex; Chronic Disease; Disease Models, Animal; Heart Failure; Losartan; Male; Neurons; Nodose Ganglion; Pressoreceptors; Rats; Rats, Sprague-Dawley; Sodium; Voltage-Gated Sodium Channels | 2015 |
Sympathoexcitation in ANG II-salt hypertension involves reduced SK channel function in the hypothalamic paraventricular nucleus.
Topics: Action Potentials; Angiotensin II; Animals; Arterial Pressure; Disease Models, Animal; Down-Regulation; Heart Rate; Hypertension; Kidney; Male; Paraventricular Hypothalamic Nucleus; Potassium Channel Blockers; Rats, Sprague-Dawley; Small-Conductance Calcium-Activated Potassium Channels; Sodium Chloride, Dietary; Splanchnic Nerves; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System; Time Factors | 2015 |
Effects of angiotensin II intervention on MMP-2, MMP-9, TIMP-1, and collagen expression in rats with pulmonary hypertension.
Topics: Angiotensin II; Animals; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type IV; Disease Models, Animal; Hypertension, Pulmonary; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2015 |
6β-hydroxytestosterone, a cytochrome P450 1B1 metabolite of testosterone, contributes to angiotensin II-induced hypertension and its pathogenesis in male mice.
Topics: Angiotensin II; Animals; Cardiomegaly; Castration; Cytochrome P-450 CYP1B1; Disease Models, Animal; Gene Expression Regulation; Hydroxytestosterones; Hypertension; Male; Mice; Random Allocation; Reactive Oxygen Species; Reference Values | 2015 |
Systemic Aldosterone, But Not Angiotensin II, Plays a Pivotal Role in the Pathogenesis of Renal Injury in Chronic Nitric Oxide-Deficient Male Rats.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Chemokine CCL2; Disease Models, Animal; Enzyme Inhibitors; Kidney; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Osteopontin; Rats; Renal Insufficiency, Chronic; Renin-Angiotensin System; RNA, Messenger; Time Factors; Transforming Growth Factor beta1 | 2015 |
Pretreatment of mesenchymal stem cells with angiotensin II enhances paracrine effects, angiogenesis, gap junction formation and therapeutic efficacy for myocardial infarction.
Topics: Analysis of Variance; Angiotensin II; Animals; Biopsy, Needle; Blotting, Western; Cell Survival; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Echocardiography; Female; Gap Junctions; Immunohistochemistry; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Infarction; Neovascularization, Physiologic; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Transplantation Conditioning; Treatment Outcome; Vascular Endothelial Growth Factor A | 2015 |
Integrative network analysis reveals molecular mechanisms of blood pressure regulation.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Angiotensin II; Animals; Blood Pressure; Body Mass Index; Cohort Studies; Disease Models, Animal; Female; Gene Regulatory Networks; Genetic Loci; Genome-Wide Association Study; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Linear Models; Male; Membrane Proteins; Mice; Mice, Knockout; Middle Aged; Polymorphism, Single Nucleotide; Protein Interaction Domains and Motifs; RNA, Messenger; Sequence Analysis, RNA; Systems Biology; Transcriptome; Young Adult | 2015 |
Renal denervation suppresses atrial fibrillation in a model of renal impairment.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Fibrillation; Autonomic Denervation; C-Reactive Protein; Catheter Ablation; Disease Models, Animal; Dogs; Fibrosis; Heart Atria; Hemodynamics; Interleukin-6; Ischemia; Kidney; Models, Cardiovascular; Norepinephrine; Renal Artery; Renal Artery Obstruction; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 2015 |
Ginsenoside Rb1 attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the JNK and p38 signaling pathways.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Apoptosis; Disease Models, Animal; Enzyme Activators; Extracellular Matrix; Ginsenosides; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Severity of Illness Index; Signal Transduction; Vascular Remodeling | 2015 |
Targeting γ-secretases protect against angiotensin II-induced cardiac hypertrophy.
Topics: Amyloid Precursor Protein Secretases; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Dibenzazepines; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Middle Aged; Muscle, Smooth, Vascular; Signal Transduction | 2015 |
Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Disease Models, Animal; Endoplasmic Reticulum Stress; Endothelium, Vascular; ErbB Receptors; Erlotinib Hydrochloride; Hypertension; Hypertrophy; Mice; Muscle, Smooth, Vascular; Phenylbutyrates; Quinazolines; Random Allocation; Role; Sensitivity and Specificity; Signal Transduction; Vascular Remodeling | 2015 |
Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Angiotensin II; Animals; Blood Pressure; Cerebral Amyloid Angiopathy; Cerebrovascular Circulation; CHO Cells; Cricetulus; Disease Models, Animal; Hypertension; Male; Mice, Inbred C57BL; Mice, Transgenic | 2016 |
Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Male; Mice, Transgenic; Microvessels; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Time Factors; Vascular Remodeling | 2015 |
Thrombospondin-1 (TSP1) contributes to the development of vascular inflammation by regulating monocytic cell motility in mouse models of abdominal aortic aneurysm.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bone Marrow Transplantation; Calcium Phosphates; Cell Line; Cell Movement; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Pancreatic Elastase; Radiation Chimera; Recombinant Proteins; Thrombospondin 1; Up-Regulation | 2015 |
Investigations in foot shock stress of variable intensity in mice: Adaptation and role of angiotensin II.
Topics: Adaptation, Psychological; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Behavior, Animal; Corticosterone; Disease Models, Animal; Electroshock; Exploratory Behavior; Foot; Mice; Motor Activity; Protective Factors; Severity of Illness Index; Stress, Psychological; Time Factors | 2015 |
Activation of the Neuroprotective Angiotensin-Converting Enzyme 2 in Rat Ischemic Stroke.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Corpus Striatum; Diminazene; Disease Models, Animal; Endothelin-1; Enzyme Activation; Imidazoles; Infarction, Middle Cerebral Artery; Infusions, Intraventricular; Leucine; Male; Neuroprotective Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger | 2015 |
Angiotensin receptors alter myocardial infarction-induced remodeling of the guinea pig cardiac plexus.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Disease Models, Animal; Electric Stimulation; Evoked Potentials; Guinea Pigs; Heart; Male; Myocardial Infarction; Norepinephrine; Presynaptic Terminals; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Presynaptic; Signal Transduction; Time Factors | 2015 |
Angiotensin II regulates brain (pro)renin receptor expression through activation of cAMP response element-binding protein.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Cell Line; CREB-Binding Protein; Desoxycorticosterone Acetate; Disease Models, Animal; Hypertension; Infusions, Intraventricular; Mice, Inbred C57BL; Paraventricular Hypothalamic Nucleus; Phosphorylation; Promoter Regions, Genetic; Prorenin Receptor; Proton-Translocating ATPases; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin-Angiotensin System; RNA Interference; RNA, Messenger; Signal Transduction; Sodium Chloride; Time Factors; Transcription Factor AP-1; Transfection; Up-Regulation | 2015 |
ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cytokines; Dependovirus; Disease Models, Animal; Enzyme Activation; Gene Expression; Genetic Therapy; Genetic Vectors; Hepatic Stellate Cells; Inflammation Mediators; Injections, Intraperitoneal; Lipid Peroxidation; Liver Cirrhosis; Liver Function Tests; Male; MAP Kinase Signaling System; Methoxamine; Mice; NADPH Oxidases; Neovascularization, Pathologic; Organ Specificity; Oxidative Stress; Peptidyl-Dipeptidase A; RNA, Messenger | 2015 |
Tumor necrosis factor receptor-associated factor 3 is a positive regulator of pathological cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Female; Humans; Hypertrophy; Male; Mice; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; Phenylephrine; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TNF Receptor-Associated Factor 3; Up-Regulation | 2015 |
Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice.
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Apolipoproteins E; Azetidines; Diet, Western; Disease Models, Animal; Ezetimibe; Female; Hypercholesterolemia; Male; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL; Sex Factors | 2015 |
Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzoates; Disease Models, Animal; Drug Evaluation, Preclinical; Epoxide Hydrolases; Epoxy Compounds; Heart Failure; Kidney; Male; Myocardium; Peptide Fragments; Random Allocation; Rats; Renal Insufficiency; Renin-Angiotensin System; Ultrasonography; Urea | 2015 |
Microglia participate in neurogenic regulation of hypertension.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Diphtheria Toxin; Disease Models, Animal; Hypertension; Infusions, Intraventricular; Mice; Mice, Inbred C57BL; Microglia; NG-Nitroarginine Methyl Ester; Sympathetic Nervous System | 2015 |
Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD.
Topics: Angiotensin II; Animals; Desoxycorticosterone Acetate; Disease Models, Animal; Disease Progression; Female; Humans; Male; Mice; Renal Insufficiency, Chronic | 2015 |
Morphological and Biomechanical Differences in the Elastase and AngII apoE(-/-) Rodent Models of Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Blood Flow Velocity; Blood Pressure; Disease Models, Animal; Disease Progression; Humans; Mice; Mice, Knockout; Pancreatic Elastase; Rats | 2015 |
TMEM16A and myocardin form a positive feedback loop that is disrupted by KLF5 during Ang II-induced vascular remodeling.
Topics: Angiotensin II; Animals; Anoctamin-1; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chloride Channels; Disease Models, Animal; Feedback, Physiological; Humans; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Neoplasm Proteins; Nuclear Proteins; Rats; Trans-Activators; Vascular Remodeling | 2015 |
Effects of long-term chloroquine administration on the natural history of aortic aneurysms in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Autophagy; Chloroquine; Collagen; Disease Models, Animal; Disease Progression; Elastin; Male; Mice, Inbred C57BL; Mice, Knockout; Time Factors | 2015 |
Activation of central PPAR-γ attenuates angiotensin II-induced hypertension.
Topics: Angiotensin II; Anilides; Animals; Blood Pressure; Brain; Disease Models, Animal; Hypertension; Infusions, Intraventricular; Infusions, Subcutaneous; Male; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathetic Nervous System; Thiazolidinediones; Ventricular Remodeling | 2015 |
Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria.
Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Line; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Doxorubicin; Epigenesis, Genetic; Irbesartan; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Podocytes; Promoter Regions, Genetic; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Time Factors; Transfection | 2015 |
Augmented Blood Pressure Variability in Hypertension Induced by Angiotensin II in Rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Rats, Inbred SHR; Rats, Wistar | 2016 |
Pioglitazone Identifies a New Target for Aneurysm Treatment: Role of Egr1 in an Experimental Murine Model of Aortic Aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Base Sequence; Binding Sites; Calcium Chloride; Cell Line, Tumor; Disease Models, Animal; Early Growth Response Protein 1; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Macrophages; Male; Mice, Knockout; Molecular Sequence Data; Pioglitazone; PPAR gamma; Promoter Regions, Genetic; RNA Interference; Signal Transduction; Thiazolidinediones; Time Factors; Transfection; TRPP Cation Channels | 2015 |
Thirst and sodium appetite in rats with experimental nephrotic syndrome.
Topics: Angiotensin II; Animals; Antibiotics, Antineoplastic; Appetite; Blood Pressure; Bronchodilator Agents; Captopril; Disease Models, Animal; Diuretics; Doxorubicin; Drinking; Furosemide; Isoproterenol; Male; Nephrotic Syndrome; Rats; Rats, Sprague-Dawley; Renin; Sodium; Thirst; Vasoconstrictor Agents | 2015 |
Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice.
Topics: Angiotensin II; Animals; Apolipoprotein B-100; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression; Hypertension; Immunization; Kidney Diseases; Lymphocyte Depletion; Male; Mice; Mice, Knockout; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Peptides; Reactive Oxygen Species; T-Lymphocyte Subsets; Vaccines, Subunit | 2015 |
Angiotensin II increases secreted frizzled-related protein 5 (sFRP5) expression through AT1 receptor/Rho/ROCK1/JNK signaling in cardiomyocytes.
Topics: Adipokines; Amides; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Proteins; Myocytes, Cardiac; Pyridines; Rats; Tumor Necrosis Factor-alpha | 2015 |
Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm.
Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Platelet Aggregation Inhibitors | 2015 |
The effect of angoroside C on pressure overload-induced ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Captopril; Collagen; Constriction, Pathologic; Coumaric Acids; Disease Models, Animal; Endothelin-1; Heart; Heart Rate; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Scrophularia; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Trisaccharides; Ventricular Remodeling | 2015 |
Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Kidney; Mice; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Sodium Chloride, Dietary | 2015 |
Conditional knockout of collecting duct bradykinin B2 receptors exacerbates angiotensin II-induced hypertension during high salt intake.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Knockout Techniques; Hypertension; Kidney Tubules, Collecting; Male; Mice; Receptor, Bradykinin B2; Sodium Chloride, Dietary | 2016 |
Angiotensin type 1a receptor deficiency decreases amyloid β-protein generation and ameliorates brain amyloid pathology.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Angiotensin II; Animals; Brain; Disease Models, Animal; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Plaque, Amyloid; Protein Aggregation, Pathological; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Signal Transduction | 2015 |
Fibroblast Angiotensin II Type 1a Receptors Contribute to Angiotensin II-Induced Medial Hyperplasia in the Ascending Aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Atherosclerosis; Disease Models, Animal; DNA; Fibroblasts; Gene Expression Regulation; Genotype; Hyperplasia; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; RNA, Messenger; Tunica Media | 2015 |
Contractile Function During Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation.
Topics: Angiotensin II; Animals; Calcium; Calcium-Binding Proteins; Cardiovascular Diseases; Disease Models, Animal; Membrane Glycoproteins; Mice; Mice, Transgenic; Models, Cardiovascular; Myocardial Contraction; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Phosphorylation; Reactive Oxygen Species; Renin-Angiotensin System; Sarcoplasmic Reticulum | 2015 |
A mouse model of heart failure with preserved ejection fraction due to chronic infusion of a low subpressor dose of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Heart Failure; Infusions, Subcutaneous; Male; Mice; Stroke Volume | 2015 |
Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Cytoprotection; Disease Models, Animal; Disease Progression; Fibrosis; Kidney; Losartan; Lymphocyte Activation; Male; Nephrectomy; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sodium Chloride, Dietary; Th17 Cells; Time Factors | 2015 |
Involvement of p38 MAPK activation mediated through AT1 receptors on spinal astrocytes and neurons in angiotensin II- and III-induced nociceptive behavior in mice.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Astrocytes; Disease Models, Animal; Lumbar Vertebrae; Male; MAP Kinase Kinase 4; Mice; Neurons; Nociceptive Pain; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spinal Cord | 2015 |
Angiotensin and mineralocorticoid receptor antagonism attenuates cardiac oxidative stress in angiotensin II-infused rats.
Topics: Adrenal Glands; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Eplerenone; Heart Diseases; Hypertension; Lipid Peroxidation; Losartan; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Oxidative Stress; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction; Spironolactone; Time Factors; Tyrosine | 2015 |
Yiqi Huaju formula, a Chinese herbal medicine, reduces arterial pressure in salt‑sensitive hypertension by inhibiting renin‑angiotensin system activation.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression; Hypertension; Kidney; Male; Rats; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 2015 |
Long-term intracerebroventricular infusion of angiotensin II after kainate-induced status epilepticus: Effects on epileptogenesis, brain damage, and diurnal behavioral changes.
Topics: Angiotensin II; Animals; Anticonvulsants; Behavior, Animal; CA1 Region, Hippocampal; Circadian Rhythm; Disease Models, Animal; Infusions, Intraventricular; Kainic Acid; Male; Neuroprotective Agents; Rats; Rats, Wistar; Spatial Memory; Status Epilepticus | 2015 |
AT2R autoantibodies block angiotensin II and AT1R autoantibody-induced vasoconstriction.
Topics: Angiotensin II; Animals; Antibodies, Blocking; Arterioles; Autoantibodies; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Male; Rabbits; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstriction | 2015 |
Angiotensin-(1-7) counteracts the effects of Ang II on vascular smooth muscle cells, vascular remodeling and hemorrhagic stroke: Role of the NFкB inflammatory pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Inflammation Mediators; Intracranial Hemorrhages; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Wound Healing | 2015 |
Maternal hyperthyroidism increases the susceptibility of rat adult offspring to cardiovascular disorders.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Disease Models, Animal; Disease Susceptibility; Female; Hypertension; Hyperthyroidism; Male; Myocardial Reperfusion Injury; Plethysmography; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Thyroxine | 2015 |
Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in Hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antigens, Ly; Blood Pressure; CD11b Antigen; Cells, Cultured; Disease Models, Animal; Hydrogen Peroxide; Hypertension; Immune Tolerance; Inflammation Mediators; Lymphocyte Activation; Male; Membrane Glycoproteins; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells; NADPH Oxidase 2; NADPH Oxidases; Nephritis; NG-Nitroarginine Methyl Ester; Signal Transduction; Sodium, Dietary; T-Lymphocytes; Time Factors | 2015 |
Angiotensin II-induced TLR4 mediated abdominal aortic aneurysm in apolipoprotein E knockout mice is dependent on STAT3.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Gene Expression Regulation; Humans; Macrophages; Male; Mice; Mice, Knockout; Signal Transduction; STAT3 Transcription Factor; Toll-Like Receptor 4 | 2015 |
Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Carotid Arteries; Collagen; Diminazene; Disease Models, Animal; Intercellular Adhesion Molecule-1; Macrophages; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A; Plaque, Atherosclerotic; Vascular Cell Adhesion Molecule-1 | 2015 |
Sex differences in NMDA GluN1 plasticity in rostral ventrolateral medulla neurons containing corticotropin-releasing factor type 1 receptor following slow-pressor angiotensin II hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Gene Expression Regulation; Green Fluorescent Proteins; Hypertension; Male; Medulla Oblongata; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Receptors, Corticotropin-Releasing Hormone; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sex Characteristics; Stilbamidines; Subcellular Fractions; Tyrosine 3-Monooxygenase | 2015 |
Apocynin improving cardiac remodeling in chronic renal failure disease is associated with up-regulation of epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Acetophenones; Aged; Angiotensin II; Animals; Cardio-Renal Syndrome; Cardiotonic Agents; Cell Line; Disease Models, Animal; Epoxide Hydrolases; Female; Fibrosis; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myocytes, Cardiac; Rats, Sprague-Dawley; Stroke Volume; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling | 2015 |
Membrane-Bound Thrombomodulin Regulates Macrophage Inflammation in Abdominal Aortic Aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Calcium Chloride; Cell Membrane; Cells, Cultured; Chemotaxis; Disease Models, Animal; Elastin; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Macrophages, Peritoneal; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Retrospective Studies; RNA Interference; Signal Transduction; Thrombomodulin; Time Factors; Transfection | 2015 |
Obligatory Role for B Cells in the Development of Angiotensin II-Dependent Hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antibodies, Anti-Idiotypic; Antigens, CD20; B-Cell Activation Factor Receptor; B-Lymphocytes; Cell Proliferation; Disease Models, Animal; Hypertension; Immunoglobulin G; Mice; Mice, Knockout; Spleen; Transforming Growth Factor beta; Vascular Stiffness | 2015 |
Transfer of regulatory T cells into abortion-prone mice promotes the expansion of uterine mast cells and normalizes early pregnancy angiogenesis.
Topics: Abortion, Spontaneous; Adoptive Transfer; Angiotensin II; Animals; Cell Count; Disease Models, Animal; Female; Fetal Death; Mast Cells; Membrane Proteins; Mice; Neovascularization, Physiologic; Placenta; Pregnancy; T-Lymphocytes, Regulatory; Uterus | 2015 |
NLRP3 Deficiency Improves Angiotensin II-Induced Hypertension But Not Fetal Growth Restriction During Pregnancy.
Topics: Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Disease Models, Animal; Female; Fetal Growth Retardation; Hypertension; Hypertension, Pregnancy-Induced; Inflammasomes; Interleukin-6; Kidney; Mice; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Placenta; Pregnancy | 2015 |
Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice.
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Malaria; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Parasitemia; Plasmodium berghei; Vasoconstrictor Agents | 2015 |
Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Cells, Cultured; Cyclic N-Oxides; Disease Models, Animal; Elastic Tissue; Elastin; Free Radical Scavengers; Hypertension; Matrix Metalloproteinases; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Sirtuin 1; Spin Labels; Time Factors | 2015 |
Local corticosterone production and angiotensin-I converting enzyme shedding in a mouse model of intestinal inflammation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colitis; Colon; Corticosterone; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Enteritis; Intestinal Mucosa; Jejunal Diseases; Jejunum; Male; Mice, Inbred BALB C; Peptidyl-Dipeptidase A; Pyridines | 2015 |
Vaccination against type 1 angiotensin receptor prevents streptozotocin-induced diabetic nephropathy.
Topics: Angiotensin II; Animals; Biomarkers; Blood Chemical Analysis; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Fibrosis; Kidney Function Tests; Male; Peptide Fragments; Podocytes; Rats; Receptor, Angiotensin, Type 1; Renin; Signal Transduction; Smad3 Protein; Streptozocin; Transforming Growth Factor beta1; Vaccines | 2016 |
Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis.
Topics: Aging; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Chemokine CCL2; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Glucagon-Like Peptide-1 Receptor; Heart; Heart Diseases; Hypertension; I-kappa B Proteins; Immunohistochemistry; Incretins; Inflammation; Interleukin-10; Liraglutide; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocardium; NF-kappa B p50 Subunit; Obesity; Oxidative Stress; Real-Time Polymerase Chain Reaction; Vasoconstrictor Agents; Vimentin | 2016 |
Angiotensin-(1-7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Drug Interactions; Hypertension, Renovascular; Losartan; Male; Medulla Oblongata; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System; Treatment Outcome | 2015 |
A dilated cardiomyopathy mutation blunts adrenergic response and induces contractile dysfunction under chronic angiotensin II stress.
Topics: Actins; Adrenergic beta-1 Receptor Agonists; Age Factors; Angiotensin II; Animals; Calcium; Cardiomyopathy, Dilated; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Excitation Contraction Coupling; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mutation; Myocardial Contraction; Papillary Muscles; Phenotype; Phosphorylation; Troponin I; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure | 2015 |
Depressor effect of chymase inhibitor in mice with high salt-induced moderate hypertension.
Topics: Albuminuria; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chymases; Disease Models, Animal; Diuretics; Heart Rate; Hypertension; Male; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Serine Proteinase Inhibitors; Sodium Chloride, Dietary; Time Factors | 2015 |
Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Apolipoproteins E; Disease Models, Animal; Female; Humans; Hypercholesterolemia; Infusion Pumps, Implantable; Male; Mice; Mice, Transgenic | 2015 |
Consequences of postnatal vascular smooth muscle EGFR deletion on acute angiotensin II action.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Dose-Response Relationship, Drug; ErbB Receptors; Gene Deletion; Humans; Hypertension; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Plasminogen Activator Inhibitor 1; Signal Transduction; Time Factors; Vascular Remodeling; Vasoconstrictor Agents | 2016 |
Differential activation of renal sympathetic burst amplitude and frequency during hypoxia, stress and baroreflexes with chronic angiotensin treatment.
Topics: Action Potentials; Angiotensin II; Animals; Baroreflex; Blood Pressure; Carbon Dioxide; Chemoreceptor Cells; Disease Models, Animal; Heart Rate; Hypertension; Hypoxia; Kidney; Male; Oxygen; Pressoreceptors; Rabbits; Stress, Physiological; Sympathetic Nervous System; Time Factors | 2015 |
ANG II-induced hypertension in the VCD mouse model of menopause is prevented by estrogen replacement during perimenopause.
Topics: Angiotensin II; Animals; Aquaporin 2; Arterial Pressure; Cell Proliferation; Cyclohexenes; Disease Models, Animal; Drug Administration Schedule; Estradiol; Estrogen Replacement Therapy; Female; Hypertension; Injections, Intraperitoneal; Kidney Cortex; Menopause; Mice, Inbred C57BL; Perimenopause; Risk Factors; Time Factors; Vinyl Compounds | 2015 |
Hypertension Impairs Cerebral Blood Flow in a Mouse Model for Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Angiotensin II; Animals; Blood Pressure; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Essential Hypertension; Hippocampus; Humans; Hypertension; Male; Mice, Inbred C57BL; Mice, Transgenic; Presenilin-1; Thalamus | 2015 |
Aspirin Attenuates Angiotensin II-induced Cardiomyocyte Hypertrophy by Inhibiting the Ca(2+)/Calcineurin-NFAT Signaling Pathway.
Topics: Angiotensin II; Animals; Animals, Newborn; Aspirin; Atrial Natriuretic Factor; Calcineurin; Calcium; Calcium Signaling; Cardiovascular Agents; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypertrophy, Left Ventricular; Male; Mice; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; NFATC Transcription Factors; Phosphorylation; Stroke Volume; Ventricular Function, Left | 2016 |
Inhibition of Proteasome Activity by Low-dose Bortezomib Attenuates Angiotensin II-induced Abdominal Aortic Aneurysm in Apo E(-/-) Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bortezomib; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Proteasome Endopeptidase Complex; Proteasome Inhibitors | 2015 |
Allergic Lung Inflammation Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice.
Topics: Angiotensin II; Animals; Anti-Allergic Agents; Antibodies, Monoclonal; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Calcium Chloride; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Immunoglobulin E; Inflammation Mediators; Lung; Macrophages; Male; Mast Cells; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Pneumonia; Respiratory Hypersensitivity; Risk Factors; Signal Transduction; Vascular Remodeling | 2016 |
Cardiac stem cells transplantation enhances the expression of connexin 43 via the ANG II/AT1R/TGF-beta1 signaling pathway in a rat model of myocardial infarction.
Topics: Angiotensin II; Animals; Connexin 43; Disease Models, Animal; Male; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Stem Cell Transplantation; Transforming Growth Factor beta1 | 2015 |
A disintegrin and metalloproteinase with thrombospondin motif 1 (ADAMTS1) expression increases in acute aortic dissection.
Topics: ADAM Proteins; ADAMTS1 Protein; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Case-Control Studies; Disease Models, Animal; Female; Humans; Immunohistochemistry; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; Neutrophils; RNA, Messenger; Up-Regulation; Versicans | 2016 |
Sildenafil Protects against Myocardial Ischemia-Reperfusion Injury Following Cardiac Arrest in a Porcine Model: Possible Role of the Renin-Angiotensin System.
Topics: Angiotensin II; Animals; Apoptosis; Cardiopulmonary Resuscitation; Cardiotonic Agents; Cyclic GMP; Disease Models, Animal; Gene Expression Regulation; Heart Arrest; Hemodynamics; Male; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Phosphodiesterase 5 Inhibitors; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sildenafil Citrate; Swine | 2015 |
Central Renin-Angiotensin System Activation and Inflammation Induced by High-Fat Diet Sensitize Angiotensin II-Elicited Hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Hypertension; Inflammation; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2016 |
Hemodynamic and neural responses to renal denervation of the nerve to the clipped kidney by cryoablation in two-kidney, one-clip hypertensive rats.
Topics: Angiotensin II; Animals; Arterial Pressure; Baroreflex; Biomarkers; Constriction; Cryosurgery; Disease Models, Animal; Hemodynamics; Hypertension, Renovascular; Kidney; Male; Norepinephrine; Rats, Sprague-Dawley; Renal Artery; Renal Artery Obstruction; Sodium Chloride, Dietary; Sympathectomy; Sympathetic Nervous System; Time Factors | 2016 |
Orphan Nuclear Receptor Nur77 Inhibits Angiotensin II-Induced Vascular Remodeling via Downregulation of β-Catenin.
Topics: Angiotensin II; Animals; beta Catenin; Cardiovascular Diseases; Disease Models, Animal; DNA; Down-Regulation; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Nuclear Receptor Subfamily 4, Group A, Member 1; Vascular Remodeling | 2016 |
Voluntary Exercise Stabilizes Established Angiotensin II-Dependent Atherosclerosis in Mice through Systemic Anti-Inflammatory Effects.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Apolipoproteins E; Atherosclerosis; Biomarkers; CD4-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Inflammation Mediators; Macrophages; Mice; Mice, Knockout; Phenotype; Physical Conditioning, Animal; Plaque, Atherosclerotic | 2015 |
Differential regulation of angiotensin II-induced extracellular signal regulated kinase-1/2 and -5 in progressive glomerulonephritis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Fibrosis; Glomerular Mesangium; Glomerulonephritis; Inflammation; Mitogen-Activated Protein Kinase 3; Rats; Renin-Angiotensin System; Signal Transduction | 2016 |
Podocyte injury in diabetic nephropathy: implications of angiotensin II-dependent activation of TRPC channels.
Topics: Albuminuria; Angiotensin II; Animals; Calcium; Diabetic Nephropathies; Disease Models, Animal; Gene Expression; Podocytes; Rats; Rats, Inbred Dahl; TRPC Cation Channels | 2015 |
Alterations in the subcellular distribution of NADPH oxidase p47(phox) in hypothalamic paraventricular neurons following slow-pressor angiotensin II hypertension in female mice with accelerated ovarian failure.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; NADPH Oxidases; Neurons; Paraventricular Hypothalamic Nucleus; Postmenopause; Sex Characteristics | 2016 |
Intrarenal renin-angiotensin system mediates fatty acid-induced ER stress in the kidney.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Blood Glucose; Cell Line; Cell Survival; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Fumarates; Gene Expression Regulation; Heat-Shock Proteins; Humans; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Palmitic Acid; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Transcription Factor CHOP; Tunicamycin; Unfolded Protein Response; Valsartan | 2016 |
Angiotensinogen Exerts Effects Independent of Angiotensin II.
Topics: Amides; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Blood Pressure; Conserved Sequence; Dependovirus; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Fumarates; Genetic Vectors; Genotype; Hepatocytes; Hypertension; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Oligonucleotides, Antisense; Phenotype; Protein Binding; Protein Interaction Domains and Motifs; Receptors, LDL; Renin; Signal Transduction; Time Factors; Transduction, Genetic; Weight Gain | 2016 |
Sympathoexcitation in Rats With Chronic Heart Failure Depends on Homeobox D10 and MicroRNA-7b Inhibiting GABBR1 Translation in Paraventricular Nucleus.
Topics: 3' Untranslated Regions; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Binding Sites; Chronic Disease; Disease Models, Animal; Gene Expression Regulation; Heart Failure; HEK293 Cells; Homeodomain Proteins; Humans; Losartan; Male; Mice; MicroRNAs; Oligonucleotides, Antisense; Paraventricular Hypothalamic Nucleus; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, GABA-B; RNA Interference; Sympathetic Nervous System; Transcription Factors; Transfection | 2016 |
Fructus mume Ethanol Extract Prevents Inflammation and Normalizes the Septohippocampal Cholinergic System in a Rat Model of Chronic Cerebral Hypoperfusion.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Brain Ischemia; Choline O-Acetyltransferase; Cholinergic Agents; Chronic Disease; Cytokines; Disease Models, Animal; Fruit; Hippocampus; Infarction, Middle Cerebral Artery; Inflammation; Male; Mitogen-Activated Protein Kinases; Neuroglia; Plant Extracts; Prunus; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products | 2016 |
Chronic Metabolic Acidosis Activates Renal Tubular Sodium Chloride Cotransporter through Angiotension II-dependent WNK4-SPAK Phosphorylation Pathway.
Topics: Acidosis; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Chemical Analysis; Disease Models, Animal; Diuretics; Gene Expression; Hydrochlorothiazide; Kidney Tubules; Mice; Mice, Knockout; Phosphorylation; Protein Serine-Threonine Kinases; Renin-Angiotensin System; Signal Transduction; Sodium; Sodium Chloride Symporters; Urinalysis | 2016 |
Augmented circadian rhythm of the intrarenal renin-angiotensin systems in anti-thymocyte serum nephritis rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Antilymphocyte Serum; Circadian Rhythm; Disease Models, Animal; Hydralazine; Kidney; Lymphocytes; Male; Nephritis; Olmesartan Medoxomil; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2016 |
Mitigation of myocardial fibrosis by molecular cardiac surgery-mediated gene overexpression.
Topics: Angiotensin II; Animals; Calcium; Cardiomyopathies; Collagen; Disease Models, Animal; Enzyme Induction; Fibronectins; Fibrosis; Genetic Therapy; Heart Failure; Hemodynamics; Male; Myocardial Infarction; Myocardium; Myofibroblasts; Receptor, Angiotensin, Type 1; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sheep; Time Factors; Transforming Growth Factor beta | 2016 |
Full Expression of Cardiomyopathy Is Partly Dependent on B-Cells: A Pathway That Involves Cytokine Activation, Immunoglobulin Deposition, and Activation of Apoptosis.
Topics: Angiotensin II; Animals; Apoptosis; B-Lymphocytes; Cardiomyopathies; Collagen; Cytokines; Disease Models, Animal; Fibroblasts; Fibrosis; Genetic Predisposition to Disease; Heart Failure; Hypertrophy, Left Ventricular; Immunoglobulin G; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, SCID; Myocardium; NG-Nitroarginine Methyl Ester; Phenotype; Sialic Acid Binding Ig-like Lectin 2; Signal Transduction; Sodium Chloride; Stroke Volume; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2016 |
Hypercholesterolemia blunts the oxidative stress elicited by hypertension in venules through angiotensin II type-2 receptors.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apolipoproteins E; Cell Adhesion; Chemotaxis, Leukocyte; Cholesterol, Dietary; Disease Models, Animal; Hypercholesterolemia; Hypertension; Leukocytes; Male; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Receptor, Angiotensin, Type 2; Signal Transduction; Venules | 2016 |
Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice.
Topics: Angiotensin II; Animals; Blood Pressure; Circadian Rhythm; Diet, Sodium-Restricted; Disease Models, Animal; Hypertension; Male; Mice; Mice, Knockout; Sodium Chloride, Dietary | 2016 |
Angiotensin II Regulation of Proliferation, Differentiation, and Engraftment of Hematopoietic Stem Cells.
Topics: Angiotensin II; Animals; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Hypertension; Male; Mice; Mice, Inbred BALB C; Video Recording | 2016 |
Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts.
Topics: Angiotensin II; Animals; Disease Models, Animal; Extracellular Matrix Proteins; Fibroblasts; Gene Expression Regulation; Kidney Diseases; MAP Kinase Signaling System; Metformin; Mice; Transforming Growth Factor beta; Ureteral Obstruction | 2016 |
Pioglitazone-Incorporated Nanoparticles Prevent Plaque Destabilization and Rupture by Regulating Monocyte/Macrophage Differentiation in ApoE-/- Mice.
Topics: Administration, Intravenous; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Brachiocephalic Trunk; Cardiovascular Agents; Cathepsins; Cell Differentiation; Cells, Cultured; Chemistry, Pharmaceutical; Cytokines; Diet, High-Fat; Disease Models, Animal; Disease Progression; Drug Carriers; Inflammation Mediators; Lactic Acid; Macrophages, Peritoneal; Male; Matrix Metalloproteinases; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Nanoparticles; Phenotype; Pioglitazone; Plaque, Atherosclerotic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rupture, Spontaneous; Thiazolidinediones | 2016 |
Mechanism of IFN-γ in regulating OPN/Th17 pathway during vascular collagen remodeling of hypertension induced by ANG II.
Topics: Angiotensin II; Animals; Blood Pressure; Cell Differentiation; Cells, Cultured; Collagen Type I; Collagen Type III; Disease Models, Animal; Hypertension; Inflammation Mediators; Interferon-gamma; Interleukin-10; Interleukin-23; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 1; Nuclear Receptor Subfamily 1, Group F, Member 3; Osteopontin; Procollagen; Spleen; Th17 Cells; Transforming Growth Factor beta; Vascular Remodeling | 2015 |
Roles of Caveolin-1 in Angiotensin II-Induced Hypertrophy and Inward Remodeling of Cerebral Pial Arterioles.
Topics: Angiotensin II; Animals; Arterioles; Caveolin 1; Disease Models, Animal; Gene Expression Regulation; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; RNA; Vascular Remodeling | 2016 |
Adiponectin Upregulates MiR-133a in Cardiac Hypertrophy through AMPK Activation and Reduced ERK1/2 Phosphorylation.
Topics: Adiponectin; AMP-Activated Protein Kinases; Angiotensin II; Animals; Cardiomegaly; Connective Tissue Growth Factor; Disease Models, Animal; Echocardiography; Gene Expression; Gene Expression Regulation; Genetic Vectors; Lentivirus; Male; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Phosphorylation; Rats; Receptors, Adiponectin; Signal Transduction; Transduction, Genetic; Up-Regulation | 2016 |
Mesenchymal Stromal Cells Prevent Renal Fibrosis in a Rat Model of Unilateral Ureteral Obstruction by Suppressing the Renin-Angiotensin System via HuR.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Apoptosis; Cell Differentiation; Cell Line; Disease Models, Animal; ELAV-Like Protein 1; Fibrosis; Green Fluorescent Proteins; Humans; Immunophenotyping; Interleukin-10; Kidney; Kidney Tubules; Male; Mesenchymal Stem Cells; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Transforming Growth Factor beta; Ureteral Obstruction | 2016 |
GPER activation ameliorates aortic remodeling induced by salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Animals, Congenic; Aorta; Blood Pressure; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Genotype; Glycosaminoglycans; Hypertension; Lipid Peroxidation; Oxidative Stress; Phenylephrine; Quinolines; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin; Sodium Chloride, Dietary; Time Factors; Vascular Remodeling | 2016 |
BMP type I receptor ALK2 is required for angiotensin II-induced cardiac hypertrophy.
Topics: Activin Receptors, Type I; Activin Receptors, Type II; Angiotensin II; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein Receptors, Type I; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Inhibitor of Differentiation Protein 1; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; NFATC Transcription Factors; Phenylephrine; Phosphorylation; Pyrazoles; Pyrimidines; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Smad Proteins; Time Factors; Transfection | 2016 |
Unique Expression of Angiotensin Type-2 Receptor in Sex-Specific Distribution of Myelinated Ah-Type Baroreceptor Neuron Contributing to Sex-Dimorphic Neurocontrol of Circulation.
Topics: Action Potentials; Afferent Pathways; Analysis of Variance; Angiotensin II; Animals; Baroreflex; Blood Pressure; Disease Models, Animal; Female; Male; Nodose Ganglion; Ovariectomy; Pressoreceptors; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Sex Characteristics | 2016 |
MiR-30a regulates the atrial fibrillation-induced myocardial fibrosis by targeting snail 1.
Topics: 3' Untranslated Regions; Angiotensin II; Animals; Atrial Fibrillation; Binding Sites; Cardiomyopathies; Cell Adhesion Molecules; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression Regulation; Male; MicroRNAs; Myocardium; Rabbits; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Snail Family Transcription Factors; Time Factors; Transcription Factors; Transfection | 2015 |
Ascending Aortic Aneurysm in Angiotensin II-Infused Mice: Formation, Progression, and the Role of Focal Dissections.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; Aortic Valve Insufficiency; Aortography; Apolipoproteins E; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Elastic Tissue; Male; Mice, Inbred C57BL; Mice, Knockout; Time Factors; Ultrasonography, Doppler, Pulsed; Vascular Remodeling; X-Ray Microtomography | 2016 |
Overexpression of microRNA-99a Attenuates Cardiac Hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Enlargement; Cells, Cultured; Disease Models, Animal; Genetic Therapy; Heart Failure; Humans; Isoproterenol; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Myocytes, Cardiac; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2016 |
Basigin Promotes Cardiac Fibrosis and Failure in Response to Chronic Pressure Overload in Mice.
Topics: Angiotensin II; Animals; Animals, Newborn; Aortic Diseases; Basigin; Blood Proteins; Cells, Cultured; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibrosis; Heart Failure; Hypertrophy, Left Ventricular; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinases; Mechanotransduction, Cellular; Mice, Knockout; Myocardium; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2016 |
Comparison of sympathetic nerve activity normalization procedures in conscious rabbits.
Topics: Action Potentials; Angiotensin II; Animals; Arterial Pressure; Baroreflex; Blood Pressure Determination; Calibration; Consciousness; Constriction; Diet, High-Fat; Disease Models, Animal; Electrodiagnosis; Heart Rate; Hypertension; Kidney; Male; Models, Animal; Muscle, Skeletal; Nasopharynx; Rabbits; Renal Artery; Reproducibility of Results; Signal Processing, Computer-Assisted; Sympathetic Nervous System; Telemetry; Time Factors | 2016 |
Transient Receptor Potential Melastatin 7 Cation Channel Kinase: New Player in Angiotensin II-Induced Hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Random Allocation; Reactive Oxygen Species; Risk Assessment; TRPM Cation Channels; Up-Regulation; Ventricular Dysfunction, Left | 2016 |
6β-Hydroxytestosterone, a Cytochrome P450 1B1-Testosterone-Metabolite, Mediates Angiotensin II-Induced Renal Dysfunction in Male Mice.
Topics: Analysis of Variance; Angiotensin II; Animals; Biopsy, Needle; Castration; Cytochrome P-450 CYP1B1; Disease Models, Animal; Hydroxytestosterones; Hypertension; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Male; Mice; Oxidative Stress; Random Allocation; Reactive Oxygen Species; Reference Values; Risk Factors; RNA, Messenger | 2016 |
Concomitant inhibition of renin angiotensin system and Toll-like receptor 2 attenuates renal injury in unilateral ureteral obstructed mice.
Topics: Amides; Angiotensin II; Animals; Disease Models, Animal; Fibrosis; Fumarates; Kidney; Male; Mice, Inbred C57BL; Mice, Knockout; Nephritis, Interstitial; Renin; Renin-Angiotensin System; RNA, Messenger; Toll-Like Receptor 2; Ureteral Obstruction | 2016 |
Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34.
Topics: Angiotensin II; Animals; Behavior, Animal; Cell Line; Cerebellum; Disease Models, Animal; DNA Damage; DNA Glycosylases; Female; Frataxin; Friedreich Ataxia; Gene Expression; Gene Expression Regulation; Gene Knockdown Techniques; Inflammation; Iron-Binding Proteins; Lipopolysaccharides; Mice; Microglia; Oxidative Stress; Phenanthrenes; Poly(ADP-ribose) Polymerases; RNA, Small Interfering | 2016 |
TMEM16A contributes to angiotensin II-induced cerebral vasoconstriction via the RhoA/ROCK signaling pathway.
Topics: Amides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anoctamin-1; Basilar Artery; Cells, Cultured; Chloride Channels; Disease Models, Animal; Evoked Potentials; Hypertension; Male; Muscle, Smooth, Vascular; Protein Phosphatase 1; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstriction | 2016 |
Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II-Infused Apolipoprotein E-Deficient Mouse.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Bradykinin; Bradykinin B2 Receptor Antagonists; Calcium Phosphates; Dilatation, Pathologic; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Knockout; Neutrophil Activation; Osteopontin; Osteoprotegerin; Phenotype; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Signal Transduction; Time Factors; Tissue Culture Techniques | 2016 |
Leukocyte Calpain Deficiency Reduces Angiotensin II-Induced Inflammation and Atherosclerosis But Not Abdominal Aortic Aneurysms in Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Bone Marrow Transplantation; Calcium-Binding Proteins; Calpain; Cell Adhesion; Cell Movement; Cells, Cultured; Coculture Techniques; Cysteine Proteinase Inhibitors; Diet, High-Fat; Disease Models, Animal; Endothelial Cells; Genetic Predisposition to Disease; Inflammation; Leukocytes; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Phenotype; Receptors, LDL; Whole-Body Irradiation | 2016 |
Thrombospondin-4 knockout in hypertension protects small-artery endothelial function but induces aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Cardiomegaly; Collagen; Dilatation, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Genetic Predisposition to Disease; Hypertension; Mesenteric Arteries; Mice, Knockout; Microscopy, Electron; Phenotype; Thrombospondins; Vascular Resistance; Vasodilation; Vasodilator Agents | 2016 |
Matricellular protein CCN3 mitigates abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Elastin; Gene Deletion; Humans; MAP Kinase Signaling System; Mice; Mice, Knockout; Nephroblastoma Overexpressed Protein; Pancreatic Elastase | 2016 |
Mast Cell Inhibition Attenuates Cardiac Remodeling and Diastolic Dysfunction in Middle-aged, Ovariectomized Fischer 344 × Brown Norway Rats.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Chymases; Cromolyn Sodium; Crosses, Genetic; Diastole; Disease Models, Animal; Estrogens; Female; Fibrosis; Heart Ventricles; Hypertrophy, Left Ventricular; Infusions, Subcutaneous; Mast Cells; Ovariectomy; Rats, Inbred BN; Rats, Inbred F344; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure; Ventricular Remodeling | 2016 |
Angiotensin II Destabilizes Coronary Plaques in Watanabe Heritable Hyperlipidemic Rabbits.
Topics: Angiotensin II; Animals; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Genetic Predisposition to Disease; Heredity; Hyperlipoproteinemia Type II; Infusion Pumps, Implantable; Infusions, Subcutaneous; Myocardial Infarction; Phenotype; Plaque, Atherosclerotic; Rabbits; Time Factors | 2016 |
Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Collagen; Disease Models, Animal; Disease Progression; Elastin; Enzyme Induction; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Severity of Illness Index; Up-Regulation | 2016 |
Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation.
Topics: Angiotensin II; Animals; Blood Pressure; CD36 Antigens; Chemokine CXCL1; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Fibrosis; Fluorescent Dyes; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1beta; Interleukin-6; Kidney; Male; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; NLR Family, Pyrin Domain-Containing 3 Protein; Peptides; Renal Insufficiency, Chronic; Ureteral Obstruction | 2016 |
Angiotensin II Stimulation of Cardiac Hypertrophy and Functional Decompensation in Osteoprotegerin-Deficient Mice.
Topics: Angiotensin II; Animals; Disease Models, Animal; Follow-Up Studies; Heart Failure, Systolic; Hypertrophy, Left Ventricular; Male; Mice; Mice, Transgenic; Osteoprotegerin; Random Allocation; Rats; Rats, Wistar; Renin-Angiotensin System; Ventricular Remodeling | 2016 |
Excessive Adventitial Remodeling Leads to Early Aortic Maladaptation in Angiotensin-Induced Hypertension.
Topics: Adventitia; Analysis of Variance; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mice; Mice, Inbred C57BL; Random Allocation; Stress, Physiological; Vascular Remodeling; Vascular Stiffness | 2016 |
Cardiac-Specific EPI64C Blunts Pressure Overload-Induced Cardiac Hypertrophy.
Topics: Angiotensin II; Animals; Blotting, Western; Calcineurin; Cardiac Output, High; Cardiomegaly; Disease Models, Animal; GTPase-Activating Proteins; Haplorhini; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; Pressure; Random Allocation; Recovery of Function; Risk Assessment; Sensitivity and Specificity; Signal Transduction | 2016 |
Leptin Mediates High-Fat Diet Sensitization of Angiotensin II-Elicited Hypertension by Upregulating the Brain Renin-Angiotensin System and Inflammation.
Topics: Angiotensin II; Animals; Blood Pressure Determination; Cytokines; Diet, High-Fat; Disease Models, Animal; Hypertension; Inflammation; Leptin; Male; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Renin-Angiotensin System; RNA, Messenger; Up-Regulation | 2016 |
Ursodeoxycholic Acid Attenuates Acute Aortic Dissection Formation in Angiotensin II-Infused Apolipoprotein E-Deficient Mice Associated with Reduced ROS and Increased Nrf2 Levels.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Cholagogues and Choleretics; Disease Models, Animal; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Up-Regulation; Ursodeoxycholic Acid | 2016 |
Hypertensive retinopathy in a transgenic angiotensin-based model.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Hypertensive Retinopathy; Male; Rats, Transgenic; Renin; Renin-Angiotensin System | 2016 |
Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats.
Topics: Action Potentials; Angiotensin II; Animals; Atrial Fibrillation; Atrial Function, Left; Atrial Remodeling; Bradykinin; Cathepsin A; Connexin 43; Diabetes Mellitus, Type 2; Disease Models, Animal; Fibrosis; Heart Rate; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Protease Inhibitors; Rats, Zucker; Time Factors | 2016 |
The Expression Profile of Complement Components in Podocytes.
Topics: Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Complement System Proteins; Diabetic Nephropathies; Disease Models, Animal; Humans; Interleukin-6; Male; Microfilament Proteins; Microscopy, Confocal; Podocytes; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Tandem Mass Spectrometry; Transcriptome; Transforming Growth Factor beta | 2016 |
Peroxisome Proliferator-Activated Receptor γ Level Contributes to Structural Integrity and Component Production of Elastic Fibers in the Aorta.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Elastin; Gene Expression Regulation; Humans; Inflammation; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Middle Aged; Muscle, Smooth, Vascular; PPAR gamma | 2016 |
The complement receptor C5aR1 contributes to renal damage but protects the heart in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Hypertension; Kidney; Mice; Mice, Knockout; Myocardium; Receptor, Anaphylatoxin C5a | 2016 |
Mitochondrial Cyclophilin D in Vascular Oxidative Stress and Hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Biomarkers; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclophilins; Disease Models, Animal; Endothelium, Vascular; Hypertension; Lactones; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Random Allocation; Spiro Compounds; Superoxides; Vasodilation | 2016 |
Redistribution of NMDA Receptors in Estrogen-Receptor-β-Containing Paraventricular Hypothalamic Neurons following Slow-Pressor Angiotensin II Hypertension in Female Mice with Accelerated Ovarian Failure.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclohexenes; Disease Models, Animal; Estrous Cycle; Female; Green Fluorescent Proteins; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; Nerve Tissue Proteins; Neurons; Ovarian Diseases; Paraventricular Hypothalamic Nucleus; Reactive Oxygen Species; Receptors, Estrogen; Receptors, N-Methyl-D-Aspartate; Vinyl Compounds | 2017 |
Down-regulation of Fibulin-5 is associated with aortic dilation: role of inflammation and epigenetics.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Binding Sites; Case-Control Studies; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Down-Regulation; Epigenesis, Genetic; Extracellular Matrix Proteins; Histone Deacetylase Inhibitors; Humans; Inflammation Mediators; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Recombinant Proteins; RNA Interference; SOX9 Transcription Factor; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 2016 |
Context-dependent effects of SOCS3 in angiotensin II-induced vascular dysfunction and hypertension in mice: mechanisms and role of bone marrow-derived cells.
Topics: Angiotensin II; Animals; Aorta; Basilar Artery; Bone Marrow Cells; Bone Marrow Transplantation; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Genotype; Hypertension; Interleukin-6; Male; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Organ Culture Techniques; Phenotype; Signal Transduction; STAT3 Transcription Factor; Superoxides; Suppressor of Cytokine Signaling 3 Protein; Vasodilation; Vasodilator Agents | 2016 |
Fibulin-2 is essential for angiotensin II-induced myocardial fibrosis mediated by transforming growth factor (TGF)-β.
Topics: Angiotensin II; Animals; Calcium-Binding Proteins; Cardiomegaly; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Cardiovascular; Myocardium; Signal Transduction; Transforming Growth Factor beta1; Ventricular Remodeling | 2016 |
P‑selectin increases angiotensin II‑induced cardiac inflammation and fibrosis via platelet activation.
Topics: Angiotensin II; Animals; Blood Platelets; Disease Models, Animal; Endothelial Cells; Fibrosis; Gene Expression; Hypertension; Immunohistochemistry; Male; Mice; Mice, Knockout; Myocarditis; Myocardium; P-Selectin; Platelet Activation | 2016 |
Maternal corticosterone exposure in the mouse programs sex-specific renal adaptations in the renin-angiotensin-aldosterone system in 6-month offspring.
Topics: Angiotensin II; Animals; Blotting, Western; Corticosterone; Disease Models, Animal; Female; Kidney; Male; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Mas; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics | 2016 |
Impact of Angiotensin Type 1A Receptors in Principal Cells of the Collecting Duct on Blood Pressure and Hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Hypertension; Kidney Tubules, Collecting; Mice; Random Allocation; Receptor, Angiotensin, Type 1; Reference Values; Renin-Angiotensin System | 2016 |
Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension.
Topics: Acute Kidney Injury; Analysis of Variance; Angiotensin II; Animals; Blood Pressure Determination; Cells, Cultured; Disease Models, Animal; Hypertension; Immunoblotting; Interleukin-17; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Random Allocation; Real-Time Polymerase Chain Reaction; Sensitivity and Specificity; Sodium Chloride Symporters; Solute Carrier Family 12, Member 3 | 2016 |
Estrogen therapy may counterbalance eutrophic remodeling of coronary arteries and increase bradykinin relaxation in a rat model of menopausal hypertension.
Topics: Angiotensin II; Animals; Bradykinin; Coronary Vessels; Disease Models, Animal; Estrogen Replacement Therapy; Estrogens; Female; Hypertension; Menopause; Ovariectomy; Rats; Rats, Sprague-Dawley; Vascular Remodeling; Vasoconstrictor Agents; Vasodilator Agents | 2016 |
Simultaneous exposure to nitric oxide inhibition and angiotensin II overload: is it a murine model of mitochondrial dysfunction in nonischemic heart failure?
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart Failure; Mice; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress | 2016 |
The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas axes in pressure overload-induced cardiac remodeling in male mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Echocardiography; Hemodynamics; Hypertension; Male; Mice; Mice, Knockout; Myocardium; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction; Ventricular Remodeling | 2016 |
Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans.
Topics: Adult; Analysis of Variance; Angiotensin II; Animals; Antibodies, Monoclonal, Humanized; Cells, Cultured; Chi-Square Distribution; Disease Models, Animal; Humans; Hypertension; Kidney; Lymphocyte Activation; Mice; Middle Aged; Random Allocation; Reference Values; Sampling Studies; Statistics, Nonparametric; T-Lymphocytes, Regulatory | 2016 |
Long-Term Supplementation of Microencapsulated ursodeoxycholic Acid Prevents Hypertension in a Mouse Model of Insulin Resistance.
Topics: Angiotensin II; Animals; Capsules; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Disease Models, Animal; Hypertension; Insulin Resistance; Male; Mice; Time Factors; Ursodeoxycholic Acid | 2017 |
Periostin expression induced by oxidative stress contributes to myocardial fibrosis in a rat model of high salt-induced hypertension.
Topics: Angiotensin II; Animals; Biomarkers; Blood Pressure; Cardiomyopathies; Cell Adhesion Molecules; Disease Models, Animal; Fibrosis; Gene Expression; Gene Expression Regulation; Hypertension; Male; Oxidative Stress; Rats; Reactive Oxygen Species; Sodium Chloride, Dietary | 2016 |
Melatonin protects podocytes from angiotensin II-induced injury in an in vitro diabetic nephropathy model.
Topics: Angiotensin II; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Survival; Diabetic Nephropathies; Disease Models, Animal; In Vitro Techniques; Janus Kinases; Melatonin; Membrane Potential, Mitochondrial; Mice; Mitochondria; Oxidative Stress; Podocytes; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; STAT Transcription Factors | 2016 |
Daidzein attenuates abdominal aortic aneurysm through NF-κB, p38MAPK and TGF-β1 pathways.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Gene Expression; Isoflavones; Male; Matrix Metalloproteinase 2; Mice; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2016 |
Possible role for brain prostanoid pathways in the development of angiotensin II-salt hypertension in rats.
Topics: Angiotensin II; Animals; Brain; Disease Models, Animal; Hypertension; Male; Neurovascular Coupling; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride, Dietary | 2016 |
Whey peptide Isoleucine-Tryptophan inhibits expression and activity of matrix metalloproteinase-2 in rat aorta.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dipeptides; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Losartan; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Rats; Renin-Angiotensin System; Vascular Stiffness; Whey Proteins | 2016 |
Vascular Smooth Muscle-Specific EP4 Receptor Deletion in Mice Exacerbates Angiotensin II-Induced Renal Injury.
Topics: Angiotensin II; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Kidney Diseases; Mesenteric Arteries; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Oxidative Stress; Receptors, Prostaglandin E, EP4 Subtype; Renal Circulation | 2016 |
Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia.
Topics: Angiotensin II; Angiotensins; Animals; Blood Pressure; Disease Models, Animal; Female; Humans; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy, Animal; Signal Transduction; Sildenafil Citrate; Treatment Outcome; Vascular Endothelial Growth Factor Receptor-1 | 2016 |
p38 MAPK Inhibition Improves Synaptic Plasticity and Memory in Angiotensin II-dependent Hypertensive Mice.
Topics: Angiotensin II; Animals; Dendritic Spines; Disease Models, Animal; Hippocampus; Humans; Hypertension; Imidazoles; Long-Term Potentiation; Mice; Neuronal Plasticity; p38 Mitogen-Activated Protein Kinases; Pyramidal Cells; Signal Transduction; Thiazoles | 2016 |
Vitamin D Receptor Activation Reduces Angiotensin-II-Induced Dissecting Abdominal Aortic Aneurysm in Apolipoprotein E-Knockout Mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Apolipoproteins E; Calcitriol; Cells, Cultured; Chemokines; Chemotaxis, Leukocyte; Disease Models, Animal; Genetic Predisposition to Disease; Human Umbilical Vein Endothelial Cells; Humans; Ligands; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Phenotype; Receptors, Calcitriol; Retinoid X Receptor alpha; RNA Interference; Signal Transduction; Transfection; Vascular Endothelial Growth Factor A | 2016 |
Renal denervation significantly attenuates cardiorenal fibrosis in rats with sustained pressure overload.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Cardiomyopathies; Disease Models, Animal; Fibrosis; Heart Atria; Heart Ventricles; Humans; Kidney; Losartan; Myocardium; Natriuretic Peptide, Brain; Peptide Fragments; Procollagen; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathectomy | 2016 |
Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cytochrome P-450 CYP1B1; Disease Models, Animal; Flow Cytometry; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Oxidative Stress; Real-Time Polymerase Chain Reaction | 2016 |
Estrogen receptor beta signals to inhibition of cardiac fibrosis.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Collagen Type I; Collagen Type III; Disease Models, Animal; Estrogen Receptor beta; Fibrosis; Male; Mice; Myofibroblasts; Rats; Signal Transduction | 2016 |
The effect of resveratrol on angiotensin II levels and the rate of transcription of its receptors in the rat cardiac hypertrophy model.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Heart; Male; Myocardium; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Stilbenes; Transcription, Genetic | 2017 |
β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice.
Topics: Actins; Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Blood Pressure; Body Weight; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Humans; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Myosin Heavy Chains; Phenotype | 2016 |
α7 Nicotinic Acetylcholine Receptor Relieves Angiotensin II-Induced Senescence in Vascular Smooth Muscle Cells by Raising Nicotinamide Adenine Dinucleotide-Dependent SIRT1 Activity.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Genotype; Histone Deacetylase Inhibitors; Humans; Hypertension; Mice, Knockout; Muscle, Smooth, Vascular; NAD; Nicotinic Agonists; Oxidative Stress; Phenotype; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Sirtuin 1; Time Factors; Transfection; Up-Regulation | 2016 |
Altered PPARγ Coactivator-1 Alpha Expression in Abdominal Aortic Aneurysm: Possible Effects on Mitochondrial Biogenesis.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Citrate (si)-Synthase; Disease Models, Animal; Gene Expression Regulation; Humans; Mice, Knockout; Mitochondria; Mitochondrial Proton-Translocating ATPases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Voltage-Dependent Anion Channels | 2016 |
Effect of foxtail millet protein hydrolysates on lowering blood pressure in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Body Weight; Disease Models, Animal; Hypolipidemic Agents; Male; Organ Size; Peptidyl-Dipeptidase A; Plant Extracts; Plant Proteins; Protein Hydrolysates; Rats; Rats, Inbred SHR; Setaria Plant; Thiobarbituric Acid Reactive Substances | 2017 |
MicroRNA-214 exerts a Cardio-protective effect by inhibition of fibrosis.
Topics: Angiotensin II; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Fibroblasts; Fibrosis; Heart; Male; MicroRNAs; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Transfection; Transforming Growth Factor beta1 | 2016 |
A dipeptidyl peptidase-4 inhibitor ameliorates hypertensive cardiac remodeling via angiotensin-II/sodium-proton pump exchanger-1 axis.
Topics: Angiotensin II; Animals; Blood Pressure; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Echocardiography; Heart Failure; Hypertension; Male; Myocytes, Cardiac; Pyrazoles; Rats; Rats, Inbred SHR; Signal Transduction; Sodium-Hydrogen Exchangers; Thiazolidines; Vasodilation; Ventricular Remodeling | 2016 |
Partial inhibition of activin receptor-like kinase 4 attenuates pressure overload-induced cardiac fibrosis and improves cardiac function.
Topics: Activin Receptors, Type I; Angiotensin II; Animals; Aorta; Apoptosis; Blood Pressure; Cardiomegaly; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; Fibrosis; Haploinsufficiency; Heterozygote; Male; Mice; Myocardium; Myocytes, Cardiac; Signal Transduction; Smad2 Protein; Smad3 Protein; Stroke Volume; Transforming Growth Factor beta; Up-Regulation; Ventricular Dysfunction, Left | 2016 |
Osteoclastogenic Differentiation of Macrophages in the Development of Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Calcium Phosphates; Calcium Signaling; Cell Transdifferentiation; Diphosphonates; Disease Models, Animal; Humans; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; RAW 264.7 Cells; Tartrate-Resistant Acid Phosphatase; Time Factors; Tumor Necrosis Factor-alpha; Vascular Calcification | 2016 |
Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular Function.
Topics: Acetylcholine; Analysis of Variance; Angiotensin II; Animals; Carotid Arteries; Cerebral Arteries; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; Mice; Mice, Inbred C57BL; Nitroprusside; Random Allocation; Reference Values; rho-Associated Kinases; Vasoconstriction | 2016 |
Tert-butylhydroquinone lowers blood pressure in AngII-induced hypertension in mice via proteasome-PTEN-Akt-eNOS pathway.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hydroquinones; Hypertension; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase | 2016 |
Dysregulation of the renin-angiotensin system during lung ischemia-reperfusion injury.
Topics: Angiotensin II; Animals; Carboxypeptidases; Disease Models, Animal; Female; Lung; Lung Injury; Mice; Prolyl Oligopeptidases; Renin-Angiotensin System; Reperfusion Injury; Serine Endopeptidases | 2016 |
Qingxuan Jiangya Decoction Reverses Vascular Remodeling by Inducing Vascular Smooth Muscle Cell Apoptosis in Spontaneously Hypertensive Rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred SHR; Vascular Remodeling | 2016 |
Novel Therapeutic Role for Dipeptidyl Peptidase III in the Treatment of Hypertension.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Disease Models, Animal; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Hypertension; Mice; Mice, Inbred ICR; Random Allocation; Role; Sensitivity and Specificity; Treatment Outcome | 2016 |
Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Biomarkers; Cholesterol; Dependovirus; Disease Models, Animal; Gene Transfer Techniques; Genetic Predisposition to Disease; Genetic Vectors; Hypercholesterolemia; Male; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mutation; Oligonucleotides, Antisense; Proprotein Convertase 9; Receptors, LDL; Species Specificity; Time Factors | 2016 |
Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Fibrosis; Genetic Predisposition to Disease; Hypertension; Male; Mice, Knockout; Muscle, Smooth, Vascular; Myocardium; NADPH Oxidases; Nitric Oxide Synthase Type III; Nitrites; Phenotype; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Stromal Interaction Molecule 1; Time Factors; Transcription Factor CHOP; Transforming Growth Factor beta; Vasodilation; Vasodilator Agents | 2016 |
Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II.
Topics: ADAM17 Protein; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; ErbB Receptors; Fibrosis; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; Myocytes, Cardiac; Random Allocation; Renin-Angiotensin System; Sensitivity and Specificity; Signal Transduction; Vascular Remodeling; Ventricular Remodeling | 2016 |
Silencing of hypoxia inducible factor-1α gene attenuated angiotensin Ⅱ-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Gene Silencing; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Lentivirus; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Microcirculation; RNA Interference; RNA, Small Interfering; Signal Transduction; Time Factors; Up-Regulation | 2016 |
MicroRNA-21 Mediates Angiotensin II-Induced Liver Fibrosis by Activating NLRP3 Inflammasome/IL-1β Axis via Targeting Smad7 and Spry1.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Inflammasomes; Interleukin-1beta; Liver Cirrhosis; Membrane Proteins; MicroRNAs; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphoproteins; Rats; Smad7 Protein | 2017 |
Low-level carotid baroreflex stimulation suppresses atrial fibrillation by inhibiting left stellate ganglion activity in an acute canine model.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Atrial Remodeling; Baroreflex; Cardiac Pacing, Artificial; Carotid Arteries; Disease Models, Animal; Dogs; Electric Stimulation; Heart Atria; Models, Cardiovascular; Norepinephrine; Stellate Ganglion | 2016 |
Inhibition of BET bromodomain attenuates angiotensin II induced abdominal aortic aneurysm in ApoE
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Azepines; Cells, Cultured; Disease Models, Animal; Extracellular Matrix; Female; Gene Expression Regulation; Humans; Male; Metalloproteases; Mice; Mice, Inbred C57BL; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA; Triazoles | 2016 |
Intracellular renin increases the inward calcium current in smooth muscle cells of mesenteric artery of SHR. Implications for hypertension and vascular remodeling.
Topics: Amides; Angiotensin II; Animals; Calcium; Calcium Signaling; Disease Models, Animal; Fumarates; Humans; Hypertension; Mesenteric Arteries; Myocytes, Smooth Muscle; Rats; Renin; Vascular Remodeling; Verapamil | 2016 |
A Disintegrin and Metalloprotease-17 Regulates Pressure Overload-Induced Myocardial Hypertrophy and Dysfunction Through Proteolytic Processing of Integrin β1.
Topics: ADAM17 Protein; Angiotensin II; Animals; Cardiomyopathy, Hypertrophic; Cells, Cultured; Disease Models, Animal; Disintegrins; Echocardiography, Doppler; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Knockout; Myocytes, Cardiac; Proteolysis; Random Allocation; Rats; Ventricular Dysfunction, Left | 2016 |
Hypoxia-Inducible Factor-1α in Smooth Muscle Cells Protects Against Aortic Aneurysms-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Elastic Tissue; Genetic Predisposition to Disease; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Protein-Lysine 6-Oxidase; Tropoelastin; Vascular Remodeling | 2016 |
Novel Protective Role for Ubiquitin-Specific Protease 18 in Pathological Cardiac Remodeling.
Topics: Analysis of Variance; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Heart Failure; Mice; Mice, Knockout; Myocytes, Cardiac; Random Allocation; Role; Sensitivity and Specificity; Signal Transduction; Ubiquitin Thiolesterase; Ventricular Remodeling | 2016 |
Angiotensin II increases coronary fibrosis, cardiac hypertrophy and the incidence of myocardial infarctions in ApoE
Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Cardiomegaly; Disease Models, Animal; Fibrillin-1; Mice; Myocardial Infarction; Myocardium; Organ Size; Peptide Fragments; Treatment Outcome | 2016 |
Angiotensin II, hypertension and angiotensin II receptor antagonism: Roles in the behavioural and brain pathology of a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Blood Pressure; Brain; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Imidazoles; Maze Learning; Mice, Transgenic; Spatial Learning; Thiophenes | 2017 |
Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Epithelial Sodium Channels; Hypertension; Infusions, Intravenous; Kidney Function Tests; Male; Multivariate Analysis; Phosphorylation; Potassium Deficiency; Potassium, Dietary; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Chloride Symporters; Sodium-Hydrogen Exchangers; Water-Electrolyte Balance | 2016 |
Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the endothelial Brg1-FoxM1 complex.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiomegaly; Disease Models, Animal; DNA Helicases; Endothelial Cells; Forkhead Box Protein M1; Heart Failure; Humans; Mice; Multiprotein Complexes; Myocardium; Nuclear Proteins; Peptidyl-Dipeptidase A; Thiostrepton; Transcription Factors | 2016 |
The Role of the Rho/ROCK Pathway in Ang II and TGF-β1-Induced Atrial Remodeling.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Atrial Remodeling; Connective Tissue Growth Factor; Disease Models, Animal; Dogs; Female; Male; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Transforming Growth Factor beta1 | 2016 |
Enalapril protects against myocardial ischemia/reperfusion injury in a swine model of cardiac arrest and resuscitation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Cardiopulmonary Resuscitation; Cardiotonic Agents; Disease Models, Animal; Enalapril; Gene Expression; Heart; Heart Arrest; Humans; Immunohistochemistry; Male; Microscopy, Electron, Transmission; Myocardial Reperfusion Injury; Myocardium; Peptidyl-Dipeptidase A; Random Allocation; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Swine; Time Factors; Ventricular Fibrillation | 2016 |
B-Cell Depletion Promotes Aortic Infiltration of Immunosuppressive Cells and Is Protective of Experimental Aortic Aneurysm.
Topics: Angiotensin II; Animals; Antibodies; Antigens, CD20; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; B-Lymphocytes; Biomarkers; Cells, Cultured; Cellular Microenvironment; Coculture Techniques; Cytokines; Dendritic Cells; Disease Models, Animal; Down-Regulation; Genetic Predisposition to Disease; Immunoglobulin M; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Lymphocyte Depletion; Male; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phenotype; T-Lymphocytes, Regulatory | 2016 |
Endogenous angiotensin II in the paraventricular nucleus regulates arterial pressure during hypotension in rat, a single-unit study.
Topics: Action Potentials; Analysis of Variance; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hemorrhage; Hypotension; Imidazoles; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Wistar; Time Factors | 2017 |
Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm.
Topics: Aging; Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortitis; Apolipoproteins E; Calcium Chloride; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; NF-kappa B; Sirtuin 1 | 2016 |
Involvement of vascular peroxidase 1 in angiotensin II-induced hypertrophy of H9c2 cells.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Cell Line; Disease Models, Animal; Endothelium, Vascular; Gene Knockdown Techniques; Hemeproteins; Hydrogen Peroxide; Hypertension; Hypertrophy; Hypochlorous Acid; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NADPH Oxidase 2; Onium Compounds; Oxidative Stress; Peroxidases; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2017 |
Zofenopril exerts a cardiovascular protective effect on rats infused with angiotensin II beyond angiotensin-converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Cardiomegaly; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hydroxyproline; Hypertension; Male; Myocardium; Rats, Wistar; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2016 |
Central Angiotensin-II Increases Blood Pressure and Sympathetic Outflow via Rho Kinase Activation in Conscious Rabbits.
Topics: Analysis of Variance; Angiotensin II; Animals; Baroreflex; Consciousness; Disease Models, Animal; Hypertension; Male; Rabbits; Random Allocation; Renin-Angiotensin System; rho-Associated Kinases; Sympathetic Nervous System | 2016 |
Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular Dysfunction.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension; Male; Mice; Mice, Knockout; Receptors, Interleukin-8B; Up-Regulation; Vascular Remodeling | 2016 |
Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion.
Topics: Acetyl-CoA Carboxylase; Angiotensin II; Animals; Cardiomegaly; Diastole; Disease Models, Animal; Echocardiography; Energy Metabolism; Fatty Acids; Fibrosis; Gene Deletion; Magnetic Resonance Imaging; Male; Mice; Mice, Knockout; Myocardium; Organelle Biogenesis; Oxidation-Reduction; Oxidative Stress; Ventricular Dysfunction | 2016 |
Mnk1 (Mitogen-Activated Protein Kinase-Interacting Kinase 1) Deficiency Aggravates Cardiac Remodeling in Mice.
Topics: Analysis of Variance; Angiotensin II; Animals; Biomarkers; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Protein Serine-Threonine Kinases; Random Allocation; Signal Transduction; Ventricular Remodeling | 2016 |
Low-protein diet supplemented with ketoacids ameliorates proteinuria in 3/4 nephrectomised rats by directly inhibiting the intrarenal renin-angiotensin system.
Topics: Angiotensin II; Animals; Cell Line; Diet, Protein-Restricted; Dietary Supplements; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; Insulin Resistance; Keto Acids; Kidney; Male; Mesangial Cells; Nephrectomy; Oxidative Stress; Proteinuria; Proteomics; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Uremia | 2016 |
Effect of testosterone on the proliferation and collagen synthesis of cardiac fibroblasts induced by angiotensin II in neonatal rat.
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomyopathies; Cell Cycle; Cell Proliferation; Cells, Cultured; Collagen; Disease Models, Animal; Fibroblasts; MAP Kinase Signaling System; Myocardium; Phosphorylation; Rats; Testosterone | 2017 |
Myocyte-specific enhancer factor 2C: a novel target gene of miR-214-3p in suppressing angiotensin II-induced cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Antagomirs; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Heart Ventricles; Male; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; MicroRNAs; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; NF-kappa B; RNA Interference; Signal Transduction; Up-Regulation | 2016 |
Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).
Topics: alpha-Globins; Angiotensin II; Animals; Blood Flow Velocity; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Humans; Hypertension; Mice; Nitric Oxide Synthase; Random Allocation; Vascular Resistance; Vasodilator Agents | 2016 |
Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts.
Topics: 3' Untranslated Regions; Angiotensin II; Animals; Binding Sites; Cardiomyopathies; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Fibrosis; Gene Expression Regulation; Male; Mice, Inbred C57BL; MicroRNAs; Myocardium; Myofibroblasts; NF-kappa B; Oligonucleotides; Polycomb Repressive Complex 2; PPAR gamma; RNA Interference; Signal Transduction; Transfection | 2016 |
Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension.
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Cognitive Dysfunction; Disease Models, Animal; Hypertension; Macrophages; Male; Membrane Glycoproteins; Mice; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1 | 2016 |
Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte Apoptosis.
Topics: Albuminuria; Angiotensin II; Animals; Apoptosis; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Imidazoles; Male; Mice; Mice, Inbred Strains; p38 Mitogen-Activated Protein Kinases; Podocytes; Sirtuin 1; Tetrazoles | 2016 |
Structural and functional brain alterations in a murine model of Angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Brain; Disease Models, Animal; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Random Allocation | 2017 |
Overexpression of SerpinE2/protease nexin-1 Contribute to Pathological Cardiac Fibrosis via increasing Collagen Deposition.
Topics: Angiotensin II; Animals; Aorta; Collagen; Constriction; Disease Models, Animal; ets-Domain Protein Elk-1; Fibrosis; Gene Knockdown Techniques; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Models, Biological; Myocardium; Myofibroblasts; RNA, Messenger; Serpin E2; Transforming Growth Factor beta | 2016 |
Mineralocorticoid Receptor Deficiency in Macrophages Inhibits Atherosclerosis by Affecting Foam Cell Formation and Efferocytosis.
Topics: Angiotensin II; Animals; Apoptosis; Atherosclerosis; Cholesterol; Disease Models, Animal; Female; Foam Cells; Male; Mice; Mice, Knockout; Receptors, Mineralocorticoid; Up-Regulation | 2017 |
Caveolin-1 Deletion Prevents Hypertensive Vascular Remodeling Induced by Angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Caveolin 1; Disease Models, Animal; Gene Deletion; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2017 |
The Paraoxonase Gene Cluster Protects Against Abdominal Aortic Aneurysm Formation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Aryldialkylphosphatase; Cells, Cultured; Disease Models, Animal; Elastin; Extracellular Matrix; Genetic Predisposition to Disease; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Multigene Family; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Phenotype; Proteolysis; Reactive Oxygen Species; Signal Transduction | 2017 |
MicroRNA-145 Mediates the Formation of Angiotensin II-Induced Murine Abdominal Aortic Aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Disease Models, Animal; Elastin; Gene Expression Regulation, Enzymologic; Lentivirus; Matrix Metalloproteinase 2; Mice; Mice, Knockout; MicroRNAs; Transduction, Genetic; Up-Regulation | 2017 |
Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity.
Topics: Angiotensin II; Animals; Arterial Pressure; Disease Models, Animal; Epithelial Sodium Channels; Gene Expression Regulation, Enzymologic; Hypertension; Kidney Tubules; Liver; Mice, Transgenic; Natriuresis; NG-Nitroarginine Methyl Ester; Peptidyl-Dipeptidase A; Renal Elimination; Renin-Angiotensin System; Sodium Chloride, Dietary; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 3; Time Factors | 2017 |
Differential hypertensive protease expression in the thoracic versus abdominal aorta.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Pressure; Cathepsin K; Cathepsin L; Cathepsins; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypertension; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; RNA, Messenger; Vascular Remodeling | 2017 |
Fenofibrate Therapy Restores Antioxidant Protection and Improves Myocardial Insulin Resistance in a Rat Model of Metabolic Syndrome and Myocardial Ischemia: The Role of Angiotensin II.
Topics: Angiotensin II; Animals; Antioxidants; Catalase; Disease Models, Animal; Fenofibrate; Insulin; Insulin Resistance; Male; Metabolic Syndrome; Myocardial Infarction; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Superoxide Dismutase; Superoxide Dismutase-1; Triglycerides | 2016 |
Hydrochlorothiazide modulates ischemic heart failure-induced cardiac remodeling via inhibiting angiotensin II type 1 receptor pathway in rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; Diuretics; Fibroblasts; Fibrosis; Furosemide; Heart Failure; Heart Ventricles; Hydrochlorothiazide; Male; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Recovery of Function; Signal Transduction; Smad2 Protein; Stroke Volume; Transforming Growth Factor beta1; Valsartan; Ventricular Function, Left; Ventricular Remodeling | 2017 |
Phosphodiesterase 5 inhibition ameliorates angiotensin II-dependent hypertension and renal vascular dysfunction.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphodiesterase 5 Inhibitors; Renal Artery; Renal Circulation; Sildenafil Citrate; Vasodilation; Vasodilator Agents; Vinca Alkaloids | 2017 |
Cellular Repressor of E1A-Stimulated Genes Is a Critical Determinant of Vascular Remodeling in Response to Angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Protein c-ets-1; Rats, Inbred Dahl; Recombinant Proteins; Repressor Proteins; RNA Interference; Signal Transduction; Sodium Chloride, Dietary; Time Factors; Transfection; Vascular Remodeling | 2017 |
Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension.
Topics: Adoptive Transfer; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bone Marrow Transplantation; Cell Movement; Disease Models, Animal; Fingolimod Hydrochloride; Genetic Predisposition to Disease; Hypertension; Inflammation Mediators; Lymph Nodes; Lysophospholipids; Mesenteric Arteries; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysosphingolipid; Signal Transduction; Sphingosine; T-Lymphocytes; Time Factors; Vascular Remodeling | 2017 |
Nicotinamide nucleotide transhydrogenase activity impacts mitochondrial redox balance and the development of hypertension in mice.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Carotid Arteries; Cells, Cultured; Disease Models, Animal; Endothelium; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Proteins; Myography; NADP Transhydrogenase, AB-Specific; Nitric Oxide; Organophosphorus Compounds; Oxidation-Reduction; Oxidative Stress; Piperidines; Primary Cell Culture; Superoxide Dismutase; Superoxides; Vasoconstrictor Agents | 2017 |
RACK1 regulates angiotensin II-induced contractions of SHR preglomerular vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Membrane; Cells, Cultured; Disease Models, Animal; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; GTP-Binding Proteins; Hypertension; Juxtaglomerular Apparatus; Male; Microvessels; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neuropeptide Y; Phospholipase C beta; Protein Binding; Protein Transport; Rats, Inbred SHR; Rats, Inbred WKY; Receptors for Activated C Kinase; RNA Interference; Signal Transduction; Transfection; Vasoconstriction; Vasoconstrictor Agents | 2017 |
microRNA-10a Targets T-box 5 to Inhibit the Development of Cardiac Hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Gene Knockdown Techniques; Male; MicroRNAs; Random Allocation; Rats, Wistar; T-Box Domain Proteins | 2017 |
Angiotensin-Converting Enzyme 2 Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice.
Topics: Adenoviridae; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Disease Models, Animal; Gene Expression Regulation; Genetic Vectors; Green Fluorescent Proteins; Humans; Immunohistochemistry; Macrophages; Male; Matrix Metalloproteinase 13; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Peptidyl-Dipeptidase A; Signal Transduction | 2018 |
Anti-Fibrotic Effect of Losartan, an Angiotensin II Receptor Blocker, Is Mediated through Inhibition of ER Stress via Up-Regulation of SIRT1, Followed by Induction of HO-1 and Thioredoxin.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Epithelial Cells; Gene Expression; Heme Oxygenase-1; Kidney Diseases; Losartan; Mice; Sirtuin 1; Thioredoxins; Transforming Growth Factor beta; Tunicamycin | 2017 |
Endoplasmic reticulum stress inhibition attenuates hypertensive chronic kidney disease through reduction in proteinuria.
Topics: Angiotensin II; Animals; Apoptosis; Biopsy; Blood Pressure; Disease Models, Animal; Endoplasmic Reticulum Stress; Fibrosis; Gene Expression Profiling; Humans; Hypertension; Inflammation; Male; Mice; Mice, Knockout; Nephrosclerosis; Phenylbutyrates; Proteinuria; Renal Insufficiency, Chronic; Transcription Factor CHOP; Transcriptome; Urinalysis | 2017 |
NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation.
Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Dissection; Biomechanical Phenomena; Caspase 1; Cells, Cultured; Disease Models, Animal; Female; Genetic Predisposition to Disease; Glyburide; Humans; Inflammasomes; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NLR Family, Pyrin Domain-Containing 3 Protein; Phenotype; Proteolysis; Vasoconstriction | 2017 |
Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regulation; Hypertension; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Remodeling | 2017 |
The activation of the kynurenine pathway in a rat model with renovascular hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypertension, Renovascular; Kynurenine; Male; Metabolic Networks and Pathways; Rats; Rats, Wistar; Tryptophan | 2017 |
Melatonin attenuates angiotensin II-induced abdominal aortic aneurysm through the down-regulation of matrix metalloproteinases.
Topics: Angiotensin II; Animals; Antioxidants; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Melatonin; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2017 |
Pravastatin activates activator protein 2 alpha to augment the angiotensin II-induced abdominal aortic aneurysms.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Anticholesteremic Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Phosphorylation; Pravastatin; Signal Transduction; Transcription Factor AP-2 | 2017 |
Intracellular Staining and Flow Cytometry to Identify Lymphocyte Subsets within Murine Aorta, Kidney and Lymph Nodes in a Model of Hypertension.
Topics: Angiotensin II; Animals; Aorta; Cytokines; Disease Models, Animal; Flow Cytometry; Hypertension; Kidney; Lymph Nodes; Mice; Staining and Labeling; T-Lymphocyte Subsets | 2017 |
Sulforaphane Prevents Angiotensin II-Induced Testicular Cell Death via Activation of NRF2.
Topics: Angiotensin II; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Disease Models, Animal; Immunohistochemistry; Infertility, Male; Isothiocyanates; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Sulfoxides; Testis | 2017 |
Effects of the Activin A-Follistatin System on Myocardial Cell Apoptosis through the Endoplasmic Reticulum Stress Pathway in Heart Failure.
Topics: Activins; Angiotensin II; Animals; Apoptosis; Biomarkers; Caspase 3; Cell Line; Disease Models, Animal; Endoplasmic Reticulum Stress; Female; Follistatin; Heart Failure; Heart Ventricles; Hemodynamics; Immunohistochemistry; Myocytes, Cardiac; Natriuretic Peptide, Brain; Rats; Signal Transduction; Transcription Factor CHOP | 2017 |
Maternal Gestational Hypertension-Induced Sensitization of Angiotensin II Hypertension Is Reversed by Renal Denervation or Angiotensin-Converting Enzyme Inhibition in Rat Offspring.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Blood Pressure; Disease Models, Animal; Female; Hypertension; Hypertension, Pregnancy-Induced; Kidney; Male; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathectomy | 2017 |
Elevated Serotonin Interacts with Angiotensin-II to Result in Altered Valve Interstitial Cell Contractility and Remodeling.
Topics: Angiotensin II; Animals; Aortic Valve; Blood Pressure; Cell Proliferation; Cells, Cultured; Cytoskeleton; Disease Models, Animal; Female; Fibrillar Collagens; Fibrosis; Heart Valve Diseases; Hypertension; Mechanotransduction, Cellular; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Serotonin; Stroke Volume; Sus scrofa; Ventricular Function, Left | 2018 |
Cardiac Fibroblast-Specific Activating Transcription Factor 3 Protects Against Heart Failure by Suppressing MAP2K3-p38 Signaling.
Topics: Acetylation; Activating Transcription Factor 3; Angiotensin II; Animals; Binding Sites; Cells, Cultured; Disease Models, Animal; Fibroblasts; Fibrosis; Genetic Predisposition to Disease; Heart Failure; Histone Deacetylase 1; Histones; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; MAP Kinase Kinase 3; Mice, Knockout; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenotype; Promoter Regions, Genetic; Protein Kinase Inhibitors; Signal Transduction; Time Factors; Transforming Growth Factor beta; Ventricular Function, Left; Ventricular Remodeling | 2017 |
A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction.
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart Failure; Myocardial Infarction; Rats; Treatment Outcome; Vaccines, Subunit; Vasoconstrictor Agents | 2017 |
β-Arrestin-biased AT1R stimulation promotes extracellular matrix synthesis in renal fibrosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; beta-Arrestin 1; beta-Arrestin 2; Biphenyl Compounds; Cell Line; Collagen Type I; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Fibronectins; Fibrosis; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; RNA Interference; Signal Transduction; Tetrazoles; Time Factors; Transfection; Ureteral Obstruction | 2017 |
Angiotensin-(1-7) regulates angiotensin II-induced matrix metalloproteinase-8 in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Humans; Matrix Metalloproteinase 8; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Plaque, Atherosclerotic; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Time Factors | 2017 |
Emerin plays a crucial role in nuclear invagination and in the nuclear calcium transient.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Aniline Compounds; Animals; Atrial Remodeling; Calcium; Cardiomegaly; Cytoplasm; Disease Models, Animal; Endothelin-1; Fluorescent Dyes; Gene Expression Regulation; Heterocyclic Compounds, 3-Ring; Humans; Membrane Proteins; Muscular Dystrophy, Emery-Dreifuss; Myocardium; Myocytes, Cardiac; Nuclear Envelope; Nuclear Proteins; Phenylephrine; Primary Cell Culture; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Ventricular Remodeling; Xanthenes | 2017 |
Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
Topics: Aging; Angiotensin II; Animals; Cerebral Hemorrhage; Disease Models, Animal; Extracellular Matrix; Gait; Hypertension; Infusion Pumps, Implantable; Insulin-Like Growth Factor I; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Oxidative Stress; Phenotype; Psychomotor Performance | 2017 |
Angiotensin II-induced hypertension differentially affects estrogen and progestin receptors in central autonomic regulatory areas of female rats.
Topics: Angiotensin II; Animals; Autonomic Nervous System; Catecholamines; Disease Models, Animal; Female; Gene Expression Regulation; Hypertension; Hypothalamus; Infusion Pumps, Implantable; Medulla Oblongata; Microscopy, Immunoelectron; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Tyrosine 3-Monooxygenase | 2008 |
The flame that lights the fire: oxidative stress, inflammation, and renal damage in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypertension; Inflammation; Inflammation Mediators; Kidney Diseases; Mice; Mice, Knockout; Oxidative Stress | 2008 |
Role of inflammation in the development of renal damage and dysfunction in angiotensin II-induced hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Blotting, Western; Cell Movement; Cell Proliferation; Disease Models, Animal; Glomerular Filtration Rate; Hypertension; Immunohistochemistry; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrosclerosis; Probability; Random Allocation; Reactive Oxygen Species; Receptors, Chemokine; Reference Values; Sensitivity and Specificity | 2008 |
Paradoxical mineralocorticoid receptor activation and left ventricular diastolic dysfunction under high oxidative stress conditions.
Topics: Angiotensin II; Animals; Antioxidants; Cyclic N-Oxides; Diastole; Disease Models, Animal; Eplerenone; Male; Mineralocorticoid Receptor Antagonists; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Spin Labels; Spironolactone; Vasoconstrictor Agents; Ventricular Dysfunction, Left | 2008 |
Role of oxidant stress on AT1 receptor expression in neurons of rabbits with heart failure and in cultured neurons.
Topics: Angiotensin II; Animals; Antioxidants; Cells, Cultured; Chronic Disease; Cyclic N-Oxides; Disease Models, Animal; Heart Failure; Male; MAP Kinase Kinase 4; NADPH Oxidases; Neurons; Oxidative Stress; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rabbits; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; RNA, Messenger; Spin Labels; Superoxides; Transcription Factor AP-1 | 2008 |
Characterization of angiotensin II antagonism displayed by Ib, a novel nonpeptide angiotensin AT(1) receptor antagonist.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Cattle; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Injections, Intravenous; Liver; Losartan; Male; Protein Binding; Pyrroles; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Time Factors; Triazoles; Vasoconstriction | 2008 |
Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats.
Topics: Acute Disease; Analysis of Variance; Angiotensin II; Animals; Chronic Disease; Disease Models, Animal; Flavonoids; Fluorescent Antibody Technique; Heart Failure; Hemodynamics; Immunohistochemistry; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Sympathetic Nervous System | 2008 |
Exercise training improves peripheral chemoreflex function in heart failure rabbits.
Topics: Action Potentials; Angiotensin II; Animals; Cardiac Pacing, Artificial; Carotid Body; Chronic Disease; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Exercise Therapy; Heart Failure; Hemodynamics; Hypoxia; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Physical Exertion; Rabbits; Receptor, Angiotensin, Type 1; Reflex; Signal Transduction; Sympathetic Nervous System; Thiourea | 2008 |
Importance of vagally mediated bradycardia for the induction of torsade de pointes in an in vivo model.
Topics: Action Potentials; Adrenergic alpha-Agonists; Angiotensin II; Animals; Anti-Arrhythmia Agents; Blood Pressure; Bradycardia; Carbon Dioxide; Disease Models, Animal; Electrocardiography; Heart; Heart Rate; Hydrogen-Ion Concentration; Male; Oxygen; Phenylephrine; Potassium; Quaternary Ammonium Compounds; Rabbits; Reflex; Time Factors; Torsades de Pointes; Vagotomy; Vagus Nerve | 2008 |
Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Echocardiography, Doppler; Indoles; Isoproterenol; Mice; Mice, Inbred Strains; NADP; Probability; Quinolines; Random Allocation; Reactive Oxygen Species; Receptor, Serotonin, 5-HT2B; Reference Values; Sensitivity and Specificity; Serotonin Antagonists; Superoxides | 2008 |
Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK.
Topics: Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Blood Pressure; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Infusion Pumps, Implantable; Inhalation Exposure; Male; Myosin Light Chains; NADPH Oxidases; Nitric Oxide Synthase; Particle Size; Particulate Matter; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Time Factors; Vasoconstriction | 2008 |
Area-specific differences in transmitter release in central catecholaminergic neurons of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Brain Stem; Catecholamines; Disease Models, Animal; Dopamine beta-Hydroxylase; Electrophysiology; Hypertension; Losartan; Neurons; Norepinephrine; Phenethylamines; Probability; Random Allocation; Rats; Rats, Inbred SHR; Rats, Wistar; Reference Values; Sensitivity and Specificity | 2008 |
Angiotensin II increases intrarenal transforming growth factor-beta1 in rats submitted to sodium overload independently of blood pressure.
Topics: Actins; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Hypertension, Renal; Kidney; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Sodium Chloride; Transforming Growth Factor beta1; Vasoconstrictor Agents | 2008 |
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Dietary Fats; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Genetic Therapy; Humans; Male; Mice; Mice, Knockout; Neovascularization, Physiologic; Peptidyl-Dipeptidase A; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Transduction, Genetic; Vasodilation | 2008 |
Perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure sensitizes offspring to angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Carcinogens, Environmental; Cardiomegaly; Collagen; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Gestational Age; Hypertension; Kidney; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidases; Polychlorinated Dibenzodioxins; Pregnancy; Prenatal Exposure Delayed Effects; Procollagen; Renin-Angiotensin System; RNA, Messenger; Telemetry; Time Factors; Ultrasonography | 2008 |
Cardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopause.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Blotting, Western; Cardiomegaly; Collagen; Disease Models, Animal; Female; Follicle Stimulating Hormone; Hypertension; MAP Kinase Kinase Kinase 5; Menopause; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Oxidative Stress; Phosphorylation; Receptor, Angiotensin, Type 1; Signal Transduction; Superoxide Dismutase; Thioredoxins; Time Factors | 2008 |
Gene targeting and heme oxygenase-1 expression in prevention of hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Targeting; Heme Oxygenase-1; Hypertension, Renovascular; Mice; Mice, Inbred C57BL; Rats; Vasoconstrictor Agents | 2008 |
Kidney-specific induction of heme oxygenase-1 prevents angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Induction; Heme; Heme Oxygenase-1; Hypertension; Infusion Pumps; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Protoporphyrins; Spectrophotometry; Treatment Outcome | 2008 |
Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia.
Topics: Aldehydes; Angiotensin II; Animals; Antioxidants; Arterioles; Body Weight; Cyclic N-Oxides; Disease Models, Animal; Glomerular Filtration Rate; Hypertension, Renal; Hyperuricemia; Kidney Glomerulus; Male; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Oxonic Acid; Rats; Rats, Sprague-Dawley; Renal Circulation; Spin Labels; Superoxides; Tyrosine | 2008 |
Enhanced angiotensin II type 2 receptor mechanisms mediate decreases in arterial pressure attributable to chronic low-dose angiotensin II in female rats.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Heart Ventricles; Hypertension; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Vasodilation | 2008 |
Inhibition of ADP-ribosyl cyclase attenuates angiotensin II-induced cardiac hypertrophy.
Topics: ADP-ribosyl Cyclase; Angiotensin II; Animals; Azo Compounds; Calcium; Calcium Signaling; Cardiomegaly; Cell Size; Cyclic ADP-Ribose; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Renovascular; Male; Myocytes, Cardiac; Nephrectomy; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Renal Artery; src-Family Kinases | 2009 |
Inhibition of vascular smooth muscle G protein-coupled receptor kinase 2 enhances alpha1D-adrenergic receptor constriction.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Aorta; Blood Pressure; Cattle; Disease Models, Animal; Dose-Response Relationship, Drug; G-Protein-Coupled Receptor Kinase 2; Hypertension, Renovascular; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; Norepinephrine; Receptors, Adrenergic, alpha-1; Renal Artery Obstruction; Vasoconstriction | 2008 |
Intact renal afferent arteriolar autoregulatory responsiveness in db/db mice.
Topics: Albuminuria; Angiotensin II; Animals; Arterioles; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Heart Rate; Homeostasis; Male; Mannitol; Mice; Mice, Obese; Motor Activity; Receptors, Leptin; Renal Circulation; Renin-Angiotensin System; Telemetry | 2008 |
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy.
Topics: Angiotensin II; Animals; Blood Pressure; Capillaries; Cardiomegaly; Cardiomyopathies; Cell Size; Ceramides; Coronary Vessels; Disease Models, Animal; Heart Rate; Humans; Hypertension; Lipid Metabolism; Mice; Mice, Transgenic; Mitochondria, Heart; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Neovascularization, Physiologic; Oxidation-Reduction; Promoter Regions, Genetic; Skin; Time Factors; Triglycerides; Up-Regulation; Vascular Endothelial Growth Factor B; Ventricular Function, Left; Ventricular Myosins | 2008 |
Role of Menkes ATPase in angiotensin II-induced hypertension: a key modulator for extracellular superoxide dismutase function.
Topics: Acetylcholine; Adenosine Triphosphatases; Angiotensin II; Animals; Antioxidants; Aorta; Blood Pressure; Cation Transport Proteins; Copper-Transporting ATPases; Cyclic N-Oxides; Disease Models, Animal; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Spin Labels; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Vasodilation | 2008 |
A novel transcript of mouse interleukin-20 receptor acts on glomerular mesangial cells as an aggravating factor in lupus nephritis.
Topics: Angiotensin II; Animals; Cytokines; Disease Models, Animal; Glomerular Mesangium; Lipopolysaccharides; Lupus Nephritis; Mesangial Cells; Mice; Mice, Inbred DBA; Mice, Inbred NZB; Platelet-Derived Growth Factor; Reactive Oxygen Species; Receptors, Interleukin | 2008 |
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis.
Topics: Adipokines; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aortic Aneurysm, Abdominal; Apelin; Apelin Receptors; Atherosclerosis; Blood Vessels; Carrier Proteins; Cell Nucleus; Diet; Disease Models, Animal; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Nitric Oxide; Reactive Oxygen Species; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Signal Transduction; Vasoconstrictor Agents | 2008 |
Subfornical organ differentially modulates baroreflex function in normotensive and two-kidney, one-clip hypertensive rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Denervation; Disease Models, Animal; Heart Rate; Hypertension, Renal; Kidney; Male; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Subfornical Organ; Surgical Instruments; Sympathetic Nervous System; Sympathomimetics; Vasodilator Agents; Water-Electrolyte Balance | 2008 |
Expression of renin-angiotensin system and peroxisome proliferator-activated receptors in alcoholic cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Biphenyl Compounds; Cardiomyopathy, Alcoholic; Disease Models, Animal; Flavonoids; Irbesartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptidyl-Dipeptidase A; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Tetrazoles; Ventricular Remodeling | 2008 |
Cardioprotective effects of granulocyte colony-stimulating factor in angiotensin II-induced cardiac remodelling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Fibrosis; Granulocyte Colony-Stimulating Factor; Heart Rate; Humans; Hypertension; Hypertrophy, Left Ventricular; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Myocardium; Osteopontin; Peptidyl-Dipeptidase A; Phosphorylation; Recombinant Proteins; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Ventricular Function, Left; Ventricular Remodeling | 2009 |
Soluble epoxide hydrolase inhibitors reduce the development of atherosclerosis in apolipoprotein e-knockout mouse model.
Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Diet, Atherogenic; Disease Models, Animal; Epoxide Hydrolases; Inhibitory Concentration 50; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Molecular Weight; Pilot Projects; Solubility | 2008 |
Use of angiotensin II antagonists in human heart failure: function of the subtype 1 receptor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Down-Regulation; Heart Failure; Humans; Losartan; Myocardium; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System | 1995 |
Role of angiotensin II, endothelin-1 and L-type calcium channel in the development of glomerular, tubulointerstitial and perivascular fibrosis.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Calcium Channels, L-Type; Disease Models, Animal; Endothelin-1; Fibrosis; Kidney Failure, Chronic; Kidney Glomerulus; Kidney Tubules; Male; Rats | 2008 |
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Blood Pressure; Cardiomegaly; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Muscle, Smooth, Vascular; Nitroprusside; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Vasodilator Agents | 2008 |
Regulation of oxygen utilization by angiotensin II in chronic kidney disease.
Topics: Angiotensin II; Animals; Captopril; Disease Models, Animal; Kidney Diseases; Losartan; Nitric Oxide Synthase; Oxygen Consumption; Rats; Sodium | 2009 |
Changes in hemodynamic and neurohumoral control cause cardiac damage in one-kidney, one-clip hypertensive mice.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Baroreflex; Blood Pressure; Cardiomegaly; Constriction; Disease Models, Animal; Fibrosis; Heart Rate; Hemodynamics; Hypertension, Renovascular; Kidney Cortex; Male; Mice; Muscarinic Antagonists; Renal Artery; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Time Factors; Vagus Nerve | 2008 |
Nerve stimulation induced overflow of neuropeptide Y and modulation by angiotensin II in spontaneously hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Captopril; Disease Models, Animal; Electric Stimulation; Hypertension; Imidazoles; Mesenteric Arteries; Neuropeptide Y; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Splanchnic Circulation; Sympathetic Nervous System | 2008 |
Inflammation, angiotensin II, and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Immunosuppressive Agents; Inflammation; Mice; Mice, Knockout; Oxidative Stress; Rats; Rats, Inbred Dahl; Receptors, CCR2 | 2008 |
Differential [Ca2+]i signaling of vasoconstriction in mesenteric microvessels of normal and reduced uterine perfusion pregnant rats.
Topics: Angiotensin II; Animals; Calcium Signaling; Disease Models, Animal; Endothelin-1; Feedback, Physiological; Female; Hypertension, Pregnancy-Induced; Litter Size; Mesentery; Microcirculation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Uterus; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Tetradecylthioacetic acid downregulates cyclooxygenase 2 in the renal cortex of two-kidney, one-clip hypertensive rats.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Constriction; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, Animal; Down-Regulation; Hypertension, Renovascular; Infusions, Subcutaneous; Injections, Intra-Arterial; Kidney Cortex; Male; Membrane Proteins; Peroxisome Proliferator-Activated Receptors; Rats; Rats, Wistar; Renal Artery; Renal Circulation; Sulfides; Time Factors | 2008 |
Involvement of angiotensin II-dependent vascular endothelial growth factor gene expression via NADPH oxidase in the retina in a type 2 diabetic rat model.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation; NADPH Oxidases; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Retina; RNA, Messenger; Tetrazoles; Vascular Endothelial Growth Factor A | 2008 |
Genetically hypertensive Brown Norway congenic rat strains suggest intermediate traits underlying genetic hypertension.
Topics: Angiotensin II; Animals; Animals, Congenic; Blood Pressure; Disease Models, Animal; Female; Genetic Linkage; Genetic Markers; Hypertension; Male; Phenotype; Pressoreceptors; Quantitative Trait Loci; Rats; Rats, Inbred BN; Risk Factors | 2008 |
Effect of unilateral ureteral obstruction and anti-angiotensin II treatment on renal tubule and interstitial cell apoptosis in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Caspase 3; Cell Proliferation; Cell Survival; Cell Transdifferentiation; Cilazapril; Disease Models, Animal; Epithelial Cells; Kidney Tubules; Losartan; Male; Rats; Rats, Wistar; Ureteral Obstruction | 2008 |
[Angiotensin II type 2 receptor expression and its modulation in angiotensin II induced acute lung injury in rat].
Topics: Acute Lung Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Losartan; Lung; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger | 2008 |
Angiotensin II-induced contraction is attenuated by nitric oxide in afferent arterioles from the nonclipped kidney in 2K1C.
Topics: Amidohydrolases; Angiotensin II; Animals; Arginase; Arterioles; Calcium; Calcium Channels; Calcium Signaling; Disease Models, Animal; Hypertension, Renovascular; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; RNA, Messenger; TRPV Cation Channels; Vasoconstriction | 2009 |
Cardiovascular homeostasis in hypotension associated with initial stages of severe acute pancreatitis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Homeostasis; Hypotension; Male; Nitric Oxide Synthase; Pancreatitis, Acute Necrotizing; Rats; Rats, Wistar; Severity of Illness Index; Taurocholic Acid; Vasoconstriction; Vasodilation | 2008 |
Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction.
Topics: Adenylyl Cyclases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aquaporin 2; Benzimidazoles; Biphenyl Compounds; Colforsin; Cyclic AMP; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gs; Kidney Medulla; Male; Rats; Rats, Wistar; Receptors, Vasopressin; RNA, Messenger; Sodium Fluoride; Tetrazoles; Ureteral Obstruction | 2009 |
Role of NOX2 in the regulation of afferent arteriole responsiveness.
Topics: Acetophenones; Adenosine; Angiotensin II; Animals; Arterioles; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypertension; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney Cortex; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Renal Circulation; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice.
Topics: Acetamides; Administration, Oral; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Cholesterol; Chymases; Disease Models, Animal; Enzyme Activation; Enzyme Precursors; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Pyrimidines; Serine Proteinase Inhibitors | 2009 |
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Angiotensins; Animals; Cells, Cultured; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; Hypertension; Hyperuricemia; KATP Channels; Kidney; Kidney Diseases; Male; Nitric Oxide; Oxonic Acid; Propylamines; Rats; Rats, Sprague-Dawley; Urate Oxidase; Uric Acid; Xanthine Oxidase | 2008 |
Candesartan ameliorates cardiac dysfunction observed in angiotensin-converting enzyme 2-deficient mice.
Topics: Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Benzimidazoles; Biphenyl Compounds; Cardiomegaly; Disease Models, Animal; Echocardiography; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardium; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Tetrazoles | 2008 |
Benazepril, an angiotensin-converting enzyme inhibitor, alleviates renal injury in spontaneously hypertensive rats by inhibiting advanced glycation end-product-mediated pathways.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Disease Models, Animal; Female; Glycation End Products, Advanced; Hypertension; Kidney Cortex; Kidney Diseases; Male; NADPH Oxidases; Oxidative Stress; Phosphorylation; Platelet-Derived Growth Factor; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction; Transcription Factor RelA; Transforming Growth Factor beta1; Vascular Cell Adhesion Molecule-1 | 2009 |
Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Carboxypeptidases; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Renovascular; Hypertrophy; Indole Alkaloids; Kallikreins; Losartan; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Quinazolines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2009 |
Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neutrophil Infiltration; NF-kappa B; Pancreatic Elastase; Rats; Rats, Wistar; Tetrazoles; Ultrasonography; Valine; Valsartan | 2008 |
The endothelin receptor antagonist tezosentan improves renal microcirculation in a porcine model of endotoxemic shock.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Endothelin Receptor Antagonists; Endotoxemia; Female; Hemodynamics; Interleukins; Kidney; Microcirculation; Osmolar Concentration; Pyridines; Random Allocation; Swine; Tetrazoles; Treatment Outcome; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2008 |
Roles of endothelial oxidases in endothelium-derived hyperpolarizing factor responses in mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biological Factors; Blood Pressure; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glutathione Peroxidase; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidoreductases; Superoxide Dismutase; Superoxides; Vasodilation; Vasodilator Agents | 2008 |
Experimental induction of salt-sensitive hypertension is associated with lymphocyte proliferative response to HSP70.
Topics: Angiotensin II; Animals; Autoimmunity; Cell Proliferation; Cells, Cultured; Disease Models, Animal; HSP70 Heat-Shock Proteins; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Sprague-Dawley; Salt Tolerance; T-Lymphocytes | 2008 |
Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Betamethasone; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetal Development; Glucocorticoids; Hypertension; Kidney Tubules, Proximal; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Sheep | 2009 |
Hepatocyte growth factor, but not vascular endothelial growth factor, attenuates angiotensin II-induced endothelial progenitor cell senescence.
Topics: Angiotensin II; Animals; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Endothelium, Vascular; Hepatocyte Growth Factor; Hindlimb; Humans; Ischemia; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Neovascularization, Physiologic; Oxidative Stress; Phosphatidylinositol Phosphates; rac1 GTP-Binding Protein; Signal Transduction; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents | 2009 |
Impaired insulin-mediated vasorelaxation in diabetic Goto-Kakizaki rats is caused by impaired Akt phosphorylation.
Topics: Adenoviridae; Angiotensin II; Animals; Aorta; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Genetic Vectors; Humans; Insulin; Insulin Resistance; Male; Microtubule-Associated Proteins; Muscle, Smooth, Vascular; Myography; Nitric Oxide Synthase Type II; Phosphorylation; Protein Phosphatase 1; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred WKY; Recombinant Proteins; RNA Interference; Signal Transduction; Survivin; Transfection; Vasoconstriction; Vasodilation | 2009 |
Atorvastatin attenuates angiotensin II-induced inflammatory actions in the liver.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Atorvastatin; Carbon Tetrachloride; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Hepatic Stellate Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Infusion Pumps, Implantable; Intercellular Adhesion Molecule-1; Interleukin-6; Liver; Male; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Transforming Growth Factor beta1 | 2009 |
Angiotensin-converting enzyme-derived angiotensin II formation during angiotensin II-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Lisinopril; Male; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A | 2009 |
Expression and tissue localization of beta-catenin, alpha-actinin and chondroitin sulfate proteoglycan 6 is modulated during rat and human left ventricular hypertrophy.
Topics: Actinin; Angiotensin II; Animals; beta Catenin; Cell Cycle Proteins; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Chromosomal Proteins, Non-Histone; Disease Models, Animal; Extracellular Matrix; Gene Expression Profiling; Humans; Hypertrophy, Left Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 7; Myocardium; Oligonucleotide Array Sequence Analysis; Osteonectin; Rats; Rats, Sprague-Dawley; Ventricular Remodeling; Versicans | 2009 |
EGCG inhibits proliferation of cardiac fibroblasts in rats with cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antioxidants; Atrial Natriuretic Factor; Camellia sinensis; Cardiomegaly; Catechin; Cell Proliferation; Disease Models, Animal; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelins; Enzyme Inhibitors; Fibroblasts; Fibrosis; Hydroxyproline; Male; Myocardium; Nitric Oxide Synthase Type II; Nitrites; Organ Size; Plant Extracts; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transcription Factors | 2009 |
Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Arterioles; Calcium Channels; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Hydrolysis; Hypertension; Male; Mesentery; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation Coupling Factors; Proton-Translocating ATPases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; src-Family Kinases; Time Factors; Vascular Resistance; Vasoconstriction | 2009 |
The Ca(v)3.2 T-type Ca(2+) channel is required for pressure overload-induced cardiac hypertrophy in mice.
Topics: Angiotensin II; Animals; Animals, Newborn; Aorta; Blood Pressure; Calcineurin; Calcium Channel Blockers; Calcium Channels, T-Type; Calcium Signaling; Cardiomegaly; Cells, Cultured; Constriction; Disease Models, Animal; Ethosuximide; Genes, Reporter; Hypertension; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NFATC Transcription Factors; Time Factors | 2009 |
[Effects of Xiongshao capsule on the proliferation of vascular smooth muscle cells in rabbits with atherosclerosis].
Topics: Angiotensin II; Animals; Atherosclerosis; Capsules; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Male; Muscle, Smooth, Vascular; Proliferating Cell Nuclear Antigen; Rabbits | 2008 |
Plasma kallikrein mediates angiotensin II type 1 receptor-stimulated retinal vascular permeability.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood-Retinal Barrier; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Hypertension; Kallikreins; Kinins; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Retinal Artery; Streptozocin; Tetrazoles | 2009 |
Exercise training reduces cardiac angiotensin II levels and prevents cardiac dysfunction in a genetic model of sympathetic hyperactivity-induced heart failure in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Heart; Heart Failure; Heart Rate; Male; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Models, Genetic; Myocardium; Physical Conditioning, Animal; Receptors, Adrenergic, alpha-2; Renin-Angiotensin System; Sympathetic Nervous System; Ventricular Dysfunction | 2009 |
Hypertension in mice lacking the CXCR3 chemokine receptor.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Hypertension; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Muscarinic Antagonists; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Receptor, Muscarinic M3; Receptors, CXCR3; Sodium Chloride; Sp1 Transcription Factor; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Ang-II-induced Ca(2+) influx is mediated by the 1/4/5 subgroup of the transient receptor potential proteins in cultured aortic smooth muscle cells from diabetic Goto-Kakizaki rats.
Topics: Angiotensin II; Animals; Aorta; Blotting, Western; Calcium; Calcium Signaling; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Muscle, Smooth, Vascular; Polymerase Chain Reaction; Rats; Rats, Inbred WKY; RNA, Messenger; Transient Receptor Potential Channels; TRPC Cation Channels | 2009 |
Angiotensin II receptor blockade inhibits acute glomerular injuries with the alteration of receptor expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Becaplermin; Biomarkers; Blood Pressure; Cell Proliferation; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Imidazoles; Kidney Glomerulus; Male; Platelet-Derived Growth Factor; Proteinuria; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Thy-1 Antigens | 2009 |
The bone morphogenetic protein antagonist gremlin promotes vascular smooth muscle cell apoptosis.
Topics: Angioplasty, Balloon; Angiotensin II; Animals; Apoptosis; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Carotid Artery Injuries; Caspase 3; Cell Proliferation; Cells, Cultured; Chromatin Assembly and Disassembly; Cytokines; Disease Models, Animal; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Proteins; Rabbits; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Transforming Growth Factor beta1 | 2009 |
Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles.
Topics: Acute Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cell Fractionation; Cell Membrane; Cytoplasmic Vesicles; Disease Models, Animal; Diuresis; Hypertension; Infusions, Intravenous; Kidney Tubules, Distal; Male; Microscopy, Immunoelectron; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Drug; Sodium Chloride Symporters; Solute Carrier Family 12, Member 3; Symporters; Time Factors | 2009 |
Role of angiotensin II and oxidative stress in vascular insulin resistance linked to hypertension.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; C-Reactive Protein; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Insulin; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Signal Transduction; Sodium Chloride, Dietary; Spin Labels; Superoxide Dismutase; Tetrazoles; Vasodilation; Vasodilator Agents | 2009 |
Energy metabolism in human renin-gene transgenic rats: does renin contribute to obesity?
Topics: Adipocytes; Amides; Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Energy Metabolism; Fumarates; Humans; Leptin; Lipid Metabolism; Male; Obesity; Phenotype; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Thermogenesis | 2009 |
Dietary fish oil is antihypertrophic but does not enhance postischemic myocardial function in female mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Arrhythmias, Cardiac; Dietary Fats, Unsaturated; Disease Models, Animal; Estrogens; Female; Fish Oils; Genetic Predisposition to Disease; Hypertrophy; Mice; Mice, Transgenic; Myocardial Ischemia; Myocardium; Ovariectomy; Reperfusion Injury | 2009 |
The development of abdominal aortic aneurysms in mice is enhanced by benzo(a)pyrene.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Rupture; Benzo(a)pyrene; Disease Models, Animal; Elastic Tissue; Macrophages; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Smoking | 2008 |
Fluvastatin prevents podocyte injury in a murine model of HIV-associated nephropathy.
Topics: AIDS-Associated Nephropathy; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Fatty Acids, Monounsaturated; Fluorescent Antibody Technique; Fluvastatin; Genes, Wilms Tumor; Glomerulosclerosis, Focal Segmental; Immunoenzyme Techniques; Indoles; Kidney; Male; Membrane Proteins; Mice; Mice, Transgenic; Microfilament Proteins; Nephrectomy; Phenotype; Podocytes; Proteinuria | 2009 |
Red wine polyphenols prevent acceleration of neovascularization by angiotensin II in the ischemic rat hindlimb.
Topics: Angiography; Angiotensin II; Animals; Blotting, Western; Disease Models, Animal; Flavonoids; Hindlimb; Ischemia; Male; Neovascularization, Pathologic; Nitric Oxide Synthase Type III; Phenols; Polyphenols; Rats; Rats, Wistar; Vascular Endothelial Growth Factor A; Wine | 2009 |
Androgen-androgen receptor system protects against angiotensin II-induced vascular remodeling.
Topics: Androgens; Angiotensin II; Animals; Aorta, Thoracic; Atherosclerosis; Coronary Vessels; Disease Models, Animal; Lipid Peroxidation; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Androgen; Superoxides; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta1; Vasoconstrictor Agents | 2009 |
Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling.
Topics: Adenoviridae; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Collagen; Disease Models, Animal; Echocardiography; ErbB Receptors; Fibrosis; Intracellular Signaling Peptides and Proteins; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Signal Transduction | 2009 |
Cardiovascular and autonomic phenotype of db/db diabetic mice.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Cardiovascular System; Circadian Rhythm; Diabetes Complications; Diabetes Mellitus, Type 2; Disease Models, Animal; Heart Rate; Hypertension; Losartan; Male; Mice; Mice, Mutant Strains; Motor Activity; Peptidyl-Dipeptidase A; Phenotype; Receptor, Angiotensin, Type 1; Receptors, Leptin | 2009 |
Development and characterization of a mouse in vitro model of ischaemia-induced ventricular fibrillation.
Topics: Angiotensin II; Animals; Cardiac Pacing, Artificial; Catecholamines; Disease Models, Animal; Electrocardiography; Heart Rate; Male; Mice; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Perfusion; Time Factors; Ventricular Fibrillation | 2009 |
Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotype.
Topics: Angiotensin II; Animals; Apolipoproteins E; Blood Pressure; Carotid Artery Diseases; Carotid Artery, Common; Collagen Type I; Disease Models, Animal; Enzyme Activation; Fibrosis; Gene Expression Profiling; Hemorrhage; Infusion Pumps, Implantable; Infusions, Subcutaneous; Macrophages; Matrix Metalloproteinase 13; Matrix Metalloproteinase 8; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Procollagen; Severity of Illness Index; Tissue Inhibitor of Metalloproteinases | 2009 |
Effects of apocynin and losartan treatment on renal oxidative stress in a rat model of calcium oxalate nephrolithiasis.
Topics: Acetophenones; Analysis of Variance; Angiotensin II; Animals; Antioxidants; Biopsy, Needle; Blotting, Western; Calcium Oxalate; Disease Models, Animal; Immunohistochemistry; Losartan; Male; NADPH Oxidases; Nephrolithiasis; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Urinalysis | 2009 |
Augmentation of endogenous intrarenal angiotensin II levels in Val5-ANG II-infused rats.
Topics: Angiotensin II; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Hypertension, Renal; Infusion Pumps, Implantable; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstrictor Agents | 2009 |
Direct renin inhibition improves systemic insulin resistance and skeletal muscle glucose transport in a transgenic rodent model of tissue renin overexpression.
Topics: Amides; Angiotensin II; Animals; Animals, Genetically Modified; Disease Models, Animal; Fumarates; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Muscle, Skeletal; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Renin | 2009 |
ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol, Dietary; Disease Models, Animal; Hydralazine; Hypercholesterolemia; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Receptors, LDL; Risk Factors; Time Factors | 2009 |
Rosuvastatin protects against angiotensin II-induced renal injury in a dose-dependent fashion.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Collagen Type IV; Disease Models, Animal; Dose-Response Relationship, Drug; Fibronectins; Fluorescent Antibody Technique, Indirect; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Kidney Cortex; Kidney Medulla; Male; Monocytes; Necrosis; Neutrophil Infiltration; Nitric Oxide Synthase Type II; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Rosuvastatin Calcium; Sulfonamides | 2009 |
Pulse wave imaging of normal and aneurysmal abdominal aortas in vivo.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Computer Simulation; Data Interpretation, Statistical; Disease Models, Animal; Electrocardiography; Humans; Image Interpretation, Computer-Assisted; Linear Models; Mice; Mice, Inbred C57BL; Signal Processing, Computer-Assisted; Time Factors; Ultrasonography | 2009 |
Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Atmosphere Exposure Chambers; Blood Pressure; Cardiomegaly; Collagen; Disease Models, Animal; Guanine Nucleotide Exchange Factors; Hypertension; Infusion Pumps; Inhalation Exposure; Injections, Intraperitoneal; Male; Matrix Metalloproteinases, Secreted; Mice; Mice, Inbred C57BL; Myocardium; Particulate Matter; Protein Kinase Inhibitors; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstriction; Vasodilation; Ventricular Remodeling | 2009 |
Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Butadienes; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Male; MAP Kinase Kinase Kinases; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitriles; Nitroarginine; Nitroprusside; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Vasoconstriction; Vasodilation | 2009 |
Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Diabetes Mellitus; Dinoprostone; Disease Models, Animal; Hypertension; Male; Mice; Mice, Mutant Strains; Muscle, Skeletal; Prostaglandin Antagonists; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Vascular Resistance; Vasoconstrictor Agents; Xanthones | 2009 |
Acquisition of brain Na sensitivity contributes to salt-induced sympathoexcitation and cardiac dysfunction in mice with pressure overload.
Topics: Anesthesia, General; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain; Disease Models, Animal; Epinephrine; Epithelial Sodium Channels; Heart; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Infusions, Parenteral; Male; Mice; Mice, Inbred ICR; Microfilament Proteins; Myocardial Contraction; Norepinephrine; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Sodium Channel Blockers; Sodium Chloride, Dietary; Sympathetic Nervous System; Telemetry; Time Factors | 2009 |
Angiotensin II activates I kappaB kinase phosphorylation of RelA at Ser 536 to promote myofibroblast survival and liver fibrosis.
Topics: Analysis of Variance; Angiotensin II; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Hepatocytes; Humans; Immunohistochemistry; Liver Cirrhosis; Male; Microscopy, Confocal; NF-kappa B; Phosphorylation; Probability; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Transfer, Ser; Sensitivity and Specificity; Signal Transduction; Transcription Factor RelA | 2009 |
Angiotensin II regulation of renal vascular ENaC proteins.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Epithelial Sodium Channels; Hypertension, Renovascular; Infusions, Intravenous; Male; Mice; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Renal Artery; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Noninvasive imaging of angiotensin receptors after myocardial infarction.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Binding Sites; Biomarkers; Disease Models, Animal; Feasibility Studies; Fluorescent Dyes; Heart Failure; Losartan; Male; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Microscopy, Fluorescence, Multiphoton; Microscopy, Video; Myocardial Infarction; Myocardium; Radiopharmaceuticals; Receptors, Angiotensin; Technetium; Time Factors; Tomography, Emission-Computed, Single-Photon; Ventricular Remodeling; X-Ray Microtomography | 2008 |
AT(1) receptor activation regulates the mRNA expression of CAT1, CAT2, arginase-1, and DDAH2 in preglomerular vessels from angiotensin II hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arginase; Arterioles; Calcium Channels; Disease Models, Animal; Hypertension; Kidney Glomerulus; Losartan; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; TRPV Cation Channels | 2009 |
Impact of early onset obesity and hypertension on the unfolded protein response in renal tissues of juvenile sheep.
Topics: Analysis of Variance; Angiotensin II; Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; Disease Progression; Female; Hypertension; Immunohistochemistry; Kidney; Kidney Diseases; Male; Nitric Oxide; Obesity; Proteins; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Sheep; Statistics, Nonparametric; Tissue Culture Techniques | 2009 |
Cytomegalovirus infection causes an increase of arterial blood pressure.
Topics: Angiotensin II; Animals; Aorta; Atherosclerosis; Blood Pressure; Blood Vessels; Cell Line; Chi-Square Distribution; Cytokines; Cytomegalovirus Infections; Diet, Atherogenic; Disease Models, Animal; DNA, Viral; Enzyme-Linked Immunosorbent Assay; Herpesviridae Infections; Humans; Mice; Mice, Inbred C57BL; Models, Biological; Muromegalovirus; Polymerase Chain Reaction; Renin; RNA, Viral; Virus Replication | 2009 |
Chymase activity is closely related with plaque vulnerability in a hamster model of atherosclerosis.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Apoptosis; Atherosclerosis; Body Weight; Cell Degranulation; Cholesterol; Chymases; Cricetinae; Disease Models, Animal; Disease Progression; Immunohistochemistry; Inflammation; Inflammation Mediators; Lipids; Male; Mast Cells; Mesocricetus; Microscopy, Electron, Transmission; ortho-Aminobenzoates; Ovalbumin; Peptidyl-Dipeptidase A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rupture; Time Factors; Ultrasonography, Doppler, Duplex | 2009 |
PPARgamma agonist, rosiglitazone, regulates angiotensin II-induced vascular inflammation through the TLR4-dependent signaling pathway.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cell Survival; Cells, Cultured; Disease Models, Animal; Gene Expression; Gene Silencing; Hypoglycemic Agents; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Rosiglitazone; Signal Transduction; Thiazolidinediones; Toll-Like Receptor 4; Vasculitis | 2009 |
Mitochondrial Thioredoxin: novel regulator for NADPH oxidase and angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Mice; Mice, Transgenic; Mitochondria; NADPH Oxidases; Random Allocation; Reactive Oxygen Species; Sensitivity and Specificity; Thioredoxins | 2009 |
Estrous cycle-dependent neurovascular dysfunction induced by angiotensin II in the mouse neocortex.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Estrogen Receptor alpha; Estrous Cycle; Female; Free Radicals; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Neocortex; Oxidative Stress; Probability; Random Allocation; Reference Values; Risk Factors; Sensitivity and Specificity; Sex Factors | 2009 |
Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of Thioredoxin 2.
Topics: Analysis of Variance; Angiotensin II; Animals; Animals, Newborn; Blood Pressure Determination; Cardiomegaly; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxygen Consumption; Random Allocation; Reactive Oxygen Species; Reference Values; Risk Factors; Thioredoxins; Vascular Resistance; Vasoconstriction; Vasodilation | 2009 |
Ventral lamina terminalis mediates enhanced cardiovascular responses of rostral ventrolateral medulla neurons during increased dietary salt.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure Determination; Cardiovascular Diseases; Disease Models, Animal; Hemodynamics; Hypertension; Hypothalamus; Male; Medulla Oblongata; Neural Inhibition; Neurons; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors; Sensitivity and Specificity; Sodium Chloride, Dietary; Sympathetic Nervous System | 2009 |
Rosiglitazone reduces the development and rupture of experimental aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Blood Glucose; Body Weight; Cholesterol; Disease Models, Animal; E-Selectin; Humans; Hypercholesterolemia; Hypoglycemic Agents; Interleukin-6; Mice; Mice, Knockout; PPAR gamma; Receptors, Angiotensin; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2009 |
Protective effects of vasonatrin peptide against hypobaric hypoxia-induced pulmonary hypertension in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Atmospheric Pressure; Atrial Natriuretic Factor; Disease Models, Animal; Endothelin-1; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor | 2010 |
Inhibition of bilirubin metabolism induces moderate hyperbilirubinemia and attenuates ANG II-dependent hypertension in mice.
Topics: Angiotensin II; Animals; Bilirubin; Blood Pressure; Cardiomegaly; Disease Models, Animal; Glucuronosyltransferase; Hyperbilirubinemia; Hypertension; Indinavir; Male; Mice; Mice, Inbred C57BL; Nitrates; Nitrites; Organic Cation Transport Proteins; Oxidative Stress | 2009 |
Endogenous angiotensin II modulates nNOS expression in renovascular hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclic N-Oxides; Disease Models, Animal; Hypertension, Renovascular; Losartan; Male; NADPH Oxidases; Nitric Oxide Synthase Type I; Oxidative Stress; Rats; Rats, Wistar; Spin Labels | 2009 |
Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Gene Expression; Genome-Wide Association Study; Humans; Male; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Up-Regulation | 2009 |
Impairment of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Disease Progression; Hypertension, Renovascular; Infusion Pumps, Implantable; Peptide Fragments; Rats; Rats, Transgenic; Surgical Instruments; Telemetry; Vasodilator Agents | 2009 |
NF-kappaB activation is required for adaptive cardiac hypertrophy.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Disease Models, Animal; Female; Fibrosis; I-kappa B Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; NF-kappa B; NF-KappaB Inhibitor alpha; Receptor, Angiotensin, Type 1; Sex Characteristics; Signal Transduction; Ventricular Remodeling | 2009 |
Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and FasL-Fas engagement.
Topics: Angiotensin II; Animals; Apoptosis; Base Sequence; Binding Sites; Carotid Artery Injuries; Caspase 8; Cells, Cultured; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; fas Receptor; GATA6 Transcription Factor; Humans; Male; MAP Kinase Kinase Kinases; Molecular Sequence Data; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA Interference; Signal Transduction; Time Factors; Transcription, Genetic; Transfection; Up-Regulation | 2009 |
Assessment of macrophage infiltration in a murine model of abdominal aortic aneurysm.
Topics: Analysis of Variance; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Contrast Media; Dextrans; Disease Models, Animal; Ferrosoferric Oxide; Image Processing, Computer-Assisted; Inflammation; Infusion Pumps, Implantable; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice | 2009 |
Comparative antihypertensive activities of losartan and HM70186 in rats with hepatic dysfunction.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Liver Diseases; Losartan; Male; Rats; Rats, Wistar; Time Factors | 2009 |
Inhibition of soluble epoxide hydrolase attenuated atherosclerosis, abdominal aortic aneurysm formation, and dyslipidemia.
Topics: Administration, Oral; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Biological Availability; Carotid Arteries; Cholesterol; Disease Models, Animal; Down-Regulation; Dyslipidemias; Enzyme Inhibitors; Epoxide Hydrolases; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-1alpha; Interleukin-6; Interleukin-8; Ligation; Male; Mice; Mice, Knockout; Vascular Cell Adhesion Molecule-1 | 2009 |
Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3.
Topics: Angiotensin II; Animals; Cell Line; Collagen Type I; Connective Tissue Growth Factor; Disease Models, Animal; Epithelial Cells; Hypertension; Kidney Diseases; Kidney Tubules; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta; Up-Regulation | 2009 |
Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Hypertension; Infusions, Intravenous; Male; Middle Cerebral Artery; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Vasodilation; Vasodilator Agents | 2009 |
Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Heart Diseases; Heart Ventricles; Hypertension; Hypertrophy; Inflammation; Macrophages; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta; Ventricular Remodeling | 2009 |
Enhanced angiotensin-mediated excitation of renal sympathetic nerve activity within the paraventricular nucleus of anesthetized rats with heart failure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Heart Failure; Heart Rate; Kidney; Ligation; Losartan; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA, Messenger; Sympathetic Nervous System; Unconsciousness; Vasoconstrictor Agents | 2009 |
Simvastatin inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice: possible role of ERK.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Benzamides; Blood Pressure; Blotting, Western; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; MAP Kinase Kinase Kinase 3; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Random Allocation; Reference Values; Renin-Angiotensin System; Simvastatin | 2009 |
Protective actions of estrogen on angiotensin II-induced hypertension: role of central nitric oxide.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Estrogens; Female; Ganglionic Blockers; Hexamethonium; Hypertension; Immunohistochemistry; Infusion Pumps, Implantable; Infusions, Subcutaneous; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Orchiectomy; Ornithine; Ovariectomy; Paraventricular Hypothalamic Nucleus; Receptors, Estrogen; Sex Factors; Subfornical Organ; Sympathetic Nervous System; Telemetry; Time Factors; Up-Regulation | 2009 |
A role of matrix metalloproteinase-8 in atherosclerosis.
Topics: Angiotensin II; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Blood Pressure; Carotid Artery Diseases; Collagen; Coronary Stenosis; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Gene Frequency; Genetic Predisposition to Disease; Humans; Leukocyte Rolling; Macrophages; Male; Matrix Metalloproteinase 8; Mice; Mice, Knockout; Polymorphism, Single Nucleotide; Prospective Studies; Severity of Illness Index; Vascular Cell Adhesion Molecule-1 | 2009 |
Ablation of angiotensin IV receptor attenuates hypofibrinolysis via PAI-1 downregulation and reduces occlusive arterial thrombosis.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Down-Regulation; Endothelial Cells; Fibrinolysis; Hemodynamics; Hemostasis; Kidney Glomerulus; Lipopolysaccharides; Mice; Mice, Knockout; Receptors, Angiotensin; RNA, Messenger; Serpin E2; Serpins; Signal Transduction; Thrombosis; Tissue Plasminogen Activator | 2009 |
Angiotensin III modulates the nociceptive control mediated by the periaqueductal gray matter.
Topics: Analgesics; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Disease Models, Animal; Drug Interactions; Efferent Pathways; Glutamyl Aminopeptidase; Losartan; Male; Microinjections; Neural Inhibition; Nociceptors; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptides; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Angiotensin | 2009 |
Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.
Topics: Angiotensin II; Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Disease Models, Animal; GABA Agonists; GABA Antagonists; Hypertension; Infusion Pumps, Implantable; Male; Microinjections; Muscimol; NG-Nitroarginine Methyl Ester; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Time Factors; Up-Regulation | 2009 |
Ischemia-induced brain damage is enhanced in human renin and angiotensinogen double-transgenic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Pressure; Brain; Brain Ischemia; Cell Death; Disease Models, Animal; Humans; Infarction, Middle Cerebral Artery; Losartan; Male; Mice; Mice, Transgenic; Receptor, Angiotensin, Type 1; Regional Blood Flow; Renin; Severity of Illness Index; Signal Transduction | 2009 |
Shear stress regulates angiotensin type 1 receptor expression in endothelial cells.
Topics: Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Down-Regulation; Endothelial Cells; Humans; Inflammation; Injections, Intravenous; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Protein Kinase Inhibitors; Pulsatile Flow; Receptor, Angiotensin, Type 1; Regional Blood Flow; RNA, Messenger; Signal Transduction; Stress, Mechanical; Time Factors; Vascular Cell Adhesion Molecule-1 | 2009 |
Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Antioxidants; Blood Pressure; Blood Vessels; Catalase; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Homeostasis; Humans; Hydrogen Peroxide; Hypertension; Imidazoles; Ion Channels; Male; Medulla Oblongata; Microinjections; Mitochondria; Mitochondrial Proteins; NADPH Oxidases; Onium Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Rosiglitazone; Spin Labels; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Sympathetic Nervous System; Thiazolidinediones; Time Factors; Transcription Factors; Transcriptional Activation; Transduction, Genetic; Uncoupling Protein 2; Up-Regulation | 2009 |
Modulation of hepatic fibrosis by c-Jun-N-terminal kinase inhibition.
Topics: Angiotensin II; Animals; Anthracenes; Carrier Proteins; Cell Division; Cells, Cultured; Disease Models, Animal; Fatty Liver; Fibroblasts; Hepatic Stellate Cells; Hepatitis C, Chronic; Humans; Liver Cirrhosis; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Mitogen-Activated Protein Kinase 9; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Transforming Growth Factor beta | 2010 |
Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Electrocardiography; Electrophysiologic Techniques, Cardiac; Endocardium; Female; Imidazoles; Infusions, Intravenous; Losartan; Male; Myocardial Ischemia; Myocardium; Purkinje Fibers; Pyridines; Receptor, Angiotensin, Type 2; Signal Transduction; Tachycardia, Ventricular; Time Factors | 2009 |
Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II.
Topics: Adenoviridae; Angiotensin II; Animals; Brain Chemistry; Disease Models, Animal; Drinking; Gene Expression Regulation; Genetic Vectors; Hypertension; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NADPH Oxidases; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Superoxides | 2009 |
Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Disease Models, Animal; Enzyme Activation; Inflammation Mediators; Irbesartan; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardium; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Receptor, Angiotensin, Type 1; RNA, Messenger; Superoxides; Tetrazoles; Time Factors; Ultrasonography; Ventricular Remodeling | 2009 |
Early diabetes in WKY and SHR produces decrease of the responses to angiotensin II and 5-HT and changes in the NO-GMPc pathway.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Cyclic GMP; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Nitric Oxide; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Signal Transduction; Streptozocin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2009 |
Regular exercise produced cardioprotective effects on rat's heart with hypertension induced by L-NAME administration.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Body Weight; Disease Models, Animal; Heart; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Physical Conditioning, Animal; Rats | 2009 |
Major role for ACE-independent intrarenal ANG II formation in type II diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Arterioles; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Kidney; Male; Mice; Mice, Mutant Strains; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Serine Proteases; Signal Transduction; Vasoconstriction | 2010 |
Intrarenal mouse renin-angiotensin system during ANG II-induced hypertension and ACE inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Disease Models, Animal; Hypertension; Kidney; Lisinopril; Male; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 2010 |
ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis.
Topics: Angiotensin II; Animals; Cell Survival; Cells, Cultured; Collagen; Disease Models, Animal; Disease Progression; Extracellular Matrix; Glomerulonephritis; Hydrogen Peroxide; Mesangial Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 7; Phosphorylation; Rats; Rats, Inbred Strains | 2010 |
Blood pressure and renal blow flow responses in heme oxygenase-2 knockout mice.
Topics: Administration, Oral; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Female; Heme Oxygenase (Decyclizing); Hypertension; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Renal Circulation; Vascular Resistance; Vasoconstriction | 2009 |
Shift to an involvement of phosphatidylinositol 3-kinase in angiotensin II actions on nucleus tractus solitarii neurons of the spontaneously hypertensive rat.
Topics: Action Potentials; Angiotensin II; Animals; Baroreflex; Cells, Cultured; Disease Models, Animal; Heart; Hypertension; Microinjections; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Reproducibility of Results; Signal Transduction; Solitary Nucleus; Sympathetic Nervous System; Transduction, Genetic | 2009 |
Matrix metalloproteinase-8 and the regulation of blood pressure, vascular inflammation, and atherosclerotic lesion growth.
Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Disease Progression; Humans; Inflammation; Matrix Metalloproteinase 8; Mice; Mice, Knockout; Vascular Cell Adhesion Molecule-1 | 2009 |
Pressure-induced renal injury in angiotensin II versus norepinephrine-induced hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Catheterization; Disease Models, Animal; Fibrosis; Glomerulosclerosis, Focal Segmental; Heart Rate; Hypertension, Renal; Kidney Cortex Necrosis; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Sodium Chloride, Dietary; Vasoconstrictor Agents | 2009 |
Protection of angiotensin II-induced vascular hypertrophy in vascular smooth muscle-targeted receptor activity-modifying protein 2 transgenic mice.
Topics: Adrenomedullin; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Female; Hypertension; Hypertrophy; Hypotension; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Vasculitis | 2009 |
Elastase-induced intracranial aneurysms in hypertensive mice.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Enzyme Inhibitors; Hypertension; Injections; Intracranial Aneurysm; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Subarachnoid Space; Vasoconstrictor Agents | 2009 |
Cardioprotection by CaMKII-deltaB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70.
Topics: Angiotensin II; Animals; Apoptosis; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; DNA-Binding Proteins; Gene Expression Regulation; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factors | 2010 |
17beta-Estradiol induces protein S-nitrosylation in the endothelium.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Cysteine; Disease Models, Animal; Endothelial Cells; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrogen; Rats; Rats, Sprague-Dawley; Umbilical Veins; Vasoconstrictor Agents | 2010 |
Chronic vagus nerve stimulation improves autonomic control and attenuates systemic inflammation and heart failure progression in a canine high-rate pacing model.
Topics: Angiotensin II; Animals; Baroreflex; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Female; Heart Failure; Heart Rate; Male; Norepinephrine; Stroke Volume; Sympathetic Nervous System; Systemic Inflammatory Response Syndrome; Time Factors; Vagus Nerve; Vagus Nerve Stimulation; Ventricular Function, Left | 2009 |
An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Base Sequence; Chemokine CCL2; Coculture Techniques; Connective Tissue; Disease Models, Animal; DNA Primers; Humans; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, CCR2; Signal Transduction | 2009 |
Influence of hypercholesterolemia and hypertension on the integrity of the blood-brain barrier in rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood-Brain Barrier; Body Weight; Catalase; Cholesterol; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glutathione; Hypercholesterolemia; Hypertension; Lipoproteins, LDL; Male; Malondialdehyde; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phosphoproteins; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Zonula Occludens-1 Protein | 2009 |
Chymase: the other ACE?
Topics: Angiotensin II; Animals; Chymases; Diabetes Complications; Diabetic Nephropathies; Disease Models, Animal; Humans; Hypertension; Kidney; Mice; Peptidyl-Dipeptidase A; Receptors, Leptin; Signal Transduction | 2010 |
Alteration of perivascular adipose tissue function in angiotensin II-induced hypertension.
Topics: Adipose Tissue; Angiotensin II; Animals; Aorta, Thoracic; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Rate; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Wistar; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Influence of exercise and perivascular adipose tissue on coronary artery vasomotor function in a familial hypercholesterolemic porcine atherosclerosis model.
Topics: Adipose Tissue; Angiotensin II; Animals; Atherosclerosis; Bradykinin; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Hyperlipoproteinemia Type II; Male; Nitroprusside; Physical Exertion; Sedentary Behavior; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2010 |
Mechanisms of blood pressure reduction by prolonged activation of the baroreflex.
Topics: Afferent Pathways; Angiotensin II; Animals; Baroreflex; Blood Pressure; Clinical Trials as Topic; Disease Models, Animal; Dogs; Electric Stimulation Therapy; Humans; Hypertension; Nerve Fibers | 2009 |
Pharmacological inhibition of C-C chemokine receptor 2 decreases macrophage infiltration in the aortic root of the human C-C chemokine receptor 2/apolipoprotein E-/- mouse: magnetic resonance imaging assessment.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Contrast Media; Dextrans; Dietary Fats; Disease Models, Animal; Ferrosoferric Oxide; Humans; Immunohistochemistry; Infusion Pumps, Implantable; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Mice, Knockout; Mice, Transgenic; Naphthyridines; Peritonitis; Receptors, CCR2; Time Factors | 2010 |
Angiotensin II type 1 and type 2 receptors regulate basal skeletal muscle microvascular volume and glucose use.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Flow Velocity; Blood Glucose; Blood Pressure Determination; Blood Volume; Disease Models, Animal; Imidazoles; Infusions, Intravenous; Losartan; Male; Microcirculation; Muscle, Skeletal; Probability; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Vasoconstrictor Agents | 2010 |
Induction of hypertension and peripheral inflammation by reduction of extracellular superoxide dismutase in the central nervous system.
Topics: Adenoviridae; Angiotensin II; Animals; Blood Pressure Determination; Central Nervous System; Disease Models, Animal; Heart Rate; Hypertension; Inflammation; Inflammation Mediators; Integrases; Mice; Mice, Inbred C57BL; Oxidative Stress; Random Allocation; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase | 2010 |
Autonomic dysregulation in ob/ob mice is improved by inhibition of angiotensin-converting enzyme.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Disease Models, Animal; Fourier Analysis; Hypertension; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2010 |
HIVAN phenotype: consequence of epithelial mesenchymal transdifferentiation.
Topics: Actins; AIDS-Associated Nephropathy; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cadherins; Calcium-Binding Proteins; Cell Proliferation; Cell Transdifferentiation; Disease Models, Animal; Epithelial Cells; Fibroblasts; HIV-1; Infusions, Subcutaneous; Kidney Glomerulus; Kidney Tubules; Macrophages; Mice; Mice, Transgenic; Phenotype; Podocytes; Proliferating Cell Nuclear Antigen; Receptor, Angiotensin, Type 1; RNA, Messenger; S100 Calcium-Binding Protein A4; S100 Proteins; T-Lymphocytes; Telmisartan | 2010 |
Alterations in the renin-angiotensin system in a rat model of human preeclampsia.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Female; Humans; Male; Placenta; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2010 |
Calmodulin kinase II is required for angiotensin II-mediated vascular smooth muscle hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Benzylamines; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carrier Proteins; Cells, Cultured; Disease Models, Animal; Histone Deacetylases; Hypertrophy; MADS Domain Proteins; Male; MEF2 Transcription Factors; Muscle, Smooth, Vascular; Myogenic Regulatory Factors; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides | 2010 |
Effects of angiotensin metabolites in the coronary vascular bed of the spontaneously hypertensive rat: loss of angiotensin II type 2 receptor-mediated vasodilation.
Topics: Analysis of Variance; Angiotensin II; Angiotensin III; Animals; Aorta, Abdominal; Biphenyl Compounds; Coronary Circulation; Disease Models, Animal; Iliac Artery; Imidazoles; Irbesartan; Male; Probability; Pyridines; Random Allocation; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 2; Reference Values; Tetrazoles; Vasoconstriction; Vasodilation | 2010 |
Early life stress sensitizes rats to angiotensin II-induced hypertension and vascular inflammation in adult life.
Topics: Angiotensin II; Animals; Animals, Newborn; Baroreflex; Blood Pressure Determination; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension; Infusions, Intravenous; Male; Random Allocation; Rats; Rats, Inbred WKY; Reference Values; Renin-Angiotensin System; Stress, Psychological; Vasculitis; Vasoconstrictor Agents | 2010 |
Infusion of angiotensin-(1-7) reduces glomerulosclerosis through counteracting angiotensin II in experimental glomerulonephritis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Proliferation; Cells, Cultured; Collagen Type I; Disease Models, Animal; Dose-Response Relationship, Drug; Fibronectins; Fibrosis; Gene Expression Regulation; Glomerulonephritis; Infusion Pumps, Implantable; Infusions, Subcutaneous; Isoantibodies; Kidney; Male; Mesangial Cells; Peptide Fragments; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Time Factors; Transforming Growth Factor beta1 | 2010 |
Increased angiotensin II in the mesometrial triangle of a transgenic rat model of preeclampsia.
Topics: Analysis of Variance; Angiotensin II; Animals; Biomarkers; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Placenta; Pre-Eclampsia; Pregnancy; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin-Angiotensin System; RNA, Messenger | 2010 |
Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Cohort Studies; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Humans; Hypertension; Interleukin-17; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Probability; Random Allocation; Reference Values; T-Lymphocytes; Vascular Diseases | 2010 |
Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Blood Pressure; Cell Proliferation; Cells, Cultured; Chronic Disease; Collagen; Disease Models, Animal; Fibrinolysin; Fibrosis; Glomerular Filtration Rate; Imidazoles; Kidney; Kidney Diseases; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nephrectomy; Phosphorylation; Plasminogen Activator Inhibitor 1; Podocytes; Proteinuria; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Time Factors | 2010 |
Downregulated Kv4.3 expression in the RVLM as a potential mechanism for sympathoexcitation in rats with chronic heart failure.
Topics: Angiotensin II; Animals; Body Weight; Chronic Disease; Disease Models, Animal; Down-Regulation; Heart Failure; Hemodynamics; Male; Medulla Oblongata; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Shal Potassium Channels; Signal Transduction; Sympathetic Nervous System | 2010 |
Sympathetic nervous system modulation of inflammation and remodeling in the hypertensive heart.
Topics: Analysis of Variance; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypertension; Inflammation Mediators; Male; Myocytes, Cardiac; Probability; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Substance P; Sympathectomy; Sympathetic Nervous System; Ventricular Remodeling | 2010 |
Syndecan-1 amplifies angiotensin II-induced cardiac fibrosis.
Topics: Angiotensin II; Animals; Blotting, Western; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hypertension; Male; Mice; Mice, Inbred BALB C; Myocardium; Probability; Random Allocation; RNA, Messenger; Smad2 Protein; Syndecan-1 | 2010 |
Angiotensin II inhibits neuronal nitric oxide synthase activation through the ERK1/2-RSK signaling pathway to modulate central control of blood pressure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Enzyme Activation; Flavonoids; Hypertension; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Ribosomal Protein S6 Kinases; Signal Transduction; Solitary Nucleus; Spin Labels; Time Factors | 2010 |
Angiotensin-(1-7) improves cardiac remodeling and inhibits growth-promoting pathways in the heart of fructose-fed rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dietary Carbohydrates; Disease Models, Animal; Fructose; Hypertension; Hypertrophy, Left Ventricular; Insulin; Insulin Resistance; Male; Peptide Fragments; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2010 |
The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.
Topics: Albuminuria; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Dinoprostone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hypertension; Intramolecular Oxidoreductases; Kidney; Mice; Mice, Inbred DBA; Mice, Knockout; Microsomes; Probability; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2010 |
Proton magnetic resonance spectroscopy detection of neurotransmitters in dorsomedial medulla correlate with spontaneous baroreceptor reflex function.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure Determination; Disease Models, Animal; Glutamic Acid; Heart Rate; Magnetic Resonance Spectroscopy; Male; Medulla Oblongata; Neurochemistry; Neurotransmitter Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Vagus Nerve | 2010 |
Metabolomics in angiotensin II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Cardiomegaly; Disease Models, Animal; Fatty Acids; Female; Humans; Hypoxanthine; Linoleic Acids; Male; Metabolomics; Mitochondria, Heart; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sirtuin 1; Survival Rate; Tetrazoles; Valine; Valsartan | 2010 |
Role of c-Jun N-terminal kinase in the regulation of vascular tone.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; JNK Mitogen-Activated Protein Kinases; Male; Norepinephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Effects of caspase inhibitor on angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice.
Topics: Amino Acid Chloromethyl Ketones; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Caspase Inhibitors; Caspases; Cells, Cultured; Chemokine CCL2; Chemotaxis; Culture Media, Conditioned; Disease Models, Animal; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protease Inhibitors; Quinolines; Severity of Illness Index; Time Factors | 2010 |
Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-/- mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Blood Pressure; Body Weight; Cholesterol; Disease Models, Animal; Hypercholesterolemia; Lipids; Male; Mice; Mice, Knockout; Receptors, CCR2; Vasodilation | 2010 |
Modulation of angiotensin II-mediated cardiac remodeling by the MEF2A target gene Xirp2.
Topics: Angiotensin II; Animals; Apoptosis; Binding Sites; Cardiomegaly; Cytoskeletal Proteins; Disease Models, Animal; DNA-Binding Proteins; Fibrosis; Gene Expression Regulation; Infusion Pumps, Implantable; Infusions, Subcutaneous; LIM Domain Proteins; MEF2 Transcription Factors; Mice; Mice, Transgenic; Myocardium; Myogenic Regulatory Factors; Myosin Heavy Chains; Nuclear Proteins; Promoter Regions, Genetic; Signal Transduction; Transcriptional Activation; Ventricular Myosins; Ventricular Remodeling | 2010 |
An angiotensin II- and NF-kappaB-dependent mechanism increases connexin 43 in murine arteries targeted by renin-dependent hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Binding Sites; Blood Pressure; Carotid Arteries; Cell Line; Connexin 43; Connexins; Disease Models, Animal; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Gap Junction alpha-5 Protein; Genes, Reporter; Hypertension, Renovascular; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Nephrectomy; NF-kappa B; NG-Nitroarginine Methyl Ester; Phosphorylation; Promoter Regions, Genetic; Rats; Renin; Time Factors; Transfection; Up-Regulation | 2010 |
Ibudilast inhibits cerebral aneurysms by down-regulating inflammation-related molecules in the vascular wall of rats.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Line, Transformed; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Female; Humans; Intercellular Adhesion Molecule-1; Intracranial Aneurysm; Matrix Metalloproteinase 9; P-Selectin; Phosphodiesterase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2010 |
Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Disease Models, Animal; Heart Diseases; Hyperthyroidism; Hypertrophy; Imidazoles; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Thyroxine | 2010 |
Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse.
Topics: Adipokines; Angiotensin II; Animals; Aortic Diseases; Apelin; Apelin Receptors; Apolipoproteins E; Carotid Artery Diseases; Carotid Artery, Common; Carrier Proteins; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Intercellular Signaling Peptides and Proteins; Ligation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Paracrine Communication; Rats; Receptors, G-Protein-Coupled; RNA, Messenger; Time Factors; Tunica Intima; Up-Regulation | 2010 |
High fat diet containing cholesterol induce aortic aneurysm through recruitment and proliferation of circulating agranulocytes in apoE knock out mice model.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Apolipoproteins E; Biomarkers; Blood Pressure; Cell Movement; Cell Proliferation; Chemokine CCL2; Cholesterol, Dietary; Disease Models, Animal; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation; Granulocytes; Hypercholesterolemia; Intercellular Adhesion Molecule-1; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Time Factors; Vascular Cell Adhesion Molecule-1; Weight Gain | 2010 |
Biomechanics of resistance artery wall remodeling in angiotensin-II hypertension and subsequent recovery.
Topics: Angiotensin II; Animals; Biomechanical Phenomena; Blood Pressure; Carotid Arteries; Disease Models, Animal; Elasticity; Endothelium, Vascular; Hypertension, Renal; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Recovery of Function; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Parathyroid hormone-related protein induces hypertrophy in podocytes via TGF-beta(1) and p27(Kip1): implications for diabetic nephropathy.
Topics: Angiotensin II; Animals; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Nephropathies; Disease Models, Animal; Glucose; Hypertrophy; Mice; Parathyroid Hormone-Related Protein; Peptide Fragments; Podocytes; Signal Transduction; Transforming Growth Factor beta1 | 2010 |
Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Astrocytes; Biosensing Techniques; Blood Pressure; Calcium Signaling; Catecholamines; Disease Models, Animal; Genes, Reporter; Hypertension; Losartan; Medulla Oblongata; Membrane Potentials; Microscopy, Confocal; Patch-Clamp Techniques; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Tissue Culture Techniques | 2010 |
Pentosan polysulfate treatment preserves renal autoregulation in ANG II-infused hypertensive rats via normalization of P2X1 receptor activation.
Topics: Actins; Adenosine Triphosphate; Angiotensin II; Animals; Anti-Inflammatory Agents; Arterioles; Blood Pressure; Disease Models, Animal; Homeostasis; Hypertension; Kidney; Male; Pentosan Sulfuric Polyester; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X1; Transforming Growth Factor beta1; Vasoconstriction | 2010 |
[Effect of electroacupuncture of different acupoints on blood pressure, plasma angiotensin II, aldosterone and atrial natriuretic peptide in spontaneous hypertension rats].
Topics: Acupuncture Points; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Animal; Electroacupuncture; Humans; Hypertension; Male; Random Allocation; Rats; Rats, Wistar | 2009 |
Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Arthritis, Experimental; Biphenyl Compounds; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Hypertrophy; Irbesartan; Losartan; Male; Oxidative Stress; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Reduction Behavior; Tetrazoles; Vasoconstrictor Agents | 2010 |
Cellular phenotype transformation occurs during thoracic aortic aneurysm development.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Calcium Chloride; Cells, Cultured; Disease Models, Animal; Disease Progression; Endothelin-1; Extracellular Matrix Proteins; Female; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Genotype; Male; Mice; Mice, Inbred C57BL; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2010 |
Different protective actions of losartan and tempol on the renal inflammatory response to acute sodium overload.
Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Pressure; Chemokine CCL5; Cyclic N-Oxides; Disease Models, Animal; Glomerular Filtration Rate; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Kidney; Losartan; Male; Natriuresis; Nephritis; NF-kappa B; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Spin Labels; Time Factors; Transforming Growth Factor beta1; Water-Electrolyte Imbalance | 2010 |
Weight loss in obese C57BL/6 mice limits adventitial expansion of established angiotensin II-induced abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Connective Tissue; Dietary Fats; Disease Models, Animal; Disease Progression; Endoglin; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Obesity; RNA, Messenger; Weight Loss | 2010 |
Loss of STAT1 is associated with increased aortic rupture in an experimental model of aortic dissection and aneurysm formation.
Topics: Aged; Analysis of Variance; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; Apolipoproteins E; Chi-Square Distribution; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Mice; Mice, Knockout; Phosphorylation; RNA, Messenger; Severity of Illness Index; Sex Factors; STAT1 Transcription Factor; Time Factors | 2010 |
Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters.
Topics: Angiotensin II; Animals; Blotting, Western; Chymases; Cricetinae; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hypertension, Pulmonary; Hypertrophy; Immunoassay; Immunohistochemistry; Male; Oligopeptides; Pulmonary Artery; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Smad Proteins; Smoking; Time Factors; Transforming Growth Factor beta1; Up-Regulation; Ventricular Function, Right; Ventricular Pressure | 2010 |
Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Chronic Disease; Disease Models, Animal; Glomerular Filtration Rate; Hematocrit; Imidazoles; Infusion Pumps; Injections, Subcutaneous; Inulin; Kidney; Kidney Diseases; Leucine; Losartan; Male; Mice; Nephrectomy; Organ Size; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Time Factors | 2010 |
Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Female; Fibroblasts; Green Fluorescent Proteins; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; Thrombotic Microangiopathies | 2010 |
Renin-angiotensin system activation in congenital hepatic fibrosis in the PCK rat model of autosomal recessive polycystic kidney disease.
Topics: Angiotensin II; Animals; Collagen; Disease Models, Animal; Disease Progression; Gene Expression; Liver; Liver Cirrhosis; Male; Peptidyl-Dipeptidase A; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Transforming Growth Factor beta | 2010 |
Role of renal perfusion pressure versus angiotensin II on renal oxidative stress in angiotensin II-induced hypertensive rats.
Topics: Albuminuria; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Infusions, Intravenous; Kidney Cortex; Kidney Function Tests; Kidney Medulla; Linear Models; Male; Malondialdehyde; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation; Superoxides; Urinalysis; Vasoconstrictor Agents | 2010 |
Angiotensin II signaling through the AT1a and AT1b receptors does not have a role in the development of cerulein-induced chronic pancreatitis in the mouse.
Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrophy; Ceruletide; Collagen; Disease Models, Animal; Fibrosis; Losartan; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreas; Pancreatitis, Chronic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Severity of Illness Index; Signal Transduction | 2010 |
Evidence for the involvement of NADPH oxidase in ischemia/reperfusion-induced gastric damage via angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Enalapril; Enzyme Inhibitors; Gastric Mucosa; Hydrogen Peroxide; Male; NADPH Oxidases; Onium Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury | 2010 |
Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2010 |
Antihypertensive effects of Ocimum basilicum L. (OBL) on blood pressure in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Blood Pressure; Captopril; Cardiomegaly; Disease Models, Animal; Endothelin-1; Endothelin-Converting Enzymes; Hypertension, Renovascular; Kidney; Male; Metalloendopeptidases; Ocimum basilicum; Plant Extracts; Rats; Rats, Wistar | 2010 |
Vascular endothelial growth factor enhances angiotensin II-induced aneurysm formation in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Body Weight; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Enzymologic; Humans; Infusion Pumps, Implantable; Injections, Intraperitoneal; Magnetic Resonance Angiography; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Recombinant Proteins; Time Factors; Vascular Endothelial Growth Factor A | 2010 |
Antihypertensive activity of Salvia elegans Vahl. (Lamiaceae): ACE inhibition and angiotensin II antagonism.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Chromatography, Thin Layer; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Injections, Intravenous; Kinetics; Lisinopril; Losartan; Mice; Mice, Inbred ICR; Peptidyl-Dipeptidase A; Plant Components, Aerial; Plant Extracts; Salvia; Spectrophotometry, Ultraviolet | 2010 |
ACE2 overexpression ameliorates left ventricular remodeling and dysfunction in a rat model of myocardial infarction.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Fibrosis; Gene Expression; Male; Myocardial Infarction; Myocardium; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Inbred WKY; Ventricular Remodeling | 2010 |
Effects of angiotensin receptor blockade on atrial electrical remodelling and the 'second factor' in a goat burst-paced model of atrial fibrillation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Electrophysiological Phenomena; Female; Goats; Heart Atria; Receptors, Angiotensin; Tetrazoles; Time Factors; Ventricular Function | 2010 |
Angiotensin II type 1a-deficient bone marrow-derived dendritic cells produce higher levels of monocyte chemoattractant protein 1.
Topics: Angiotensin II; Animals; Bone Marrow; Chemokine CCL2; Dendritic Cells; Disease Models, Animal; Glomerulonephritis; Hypertension; Immunity, Cellular; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1 | 2010 |
Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase-ROS-CTGF pathway.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cell Proliferation; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Fibroblasts; Fibrosis; Hypertension; Male; Malondialdehyde; Myocardium; NADPH Oxidases; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors; Trimetazidine; Vasodilator Agents | 2010 |
Intracellular or extracellular heat shock protein 70 differentially regulates cardiac remodelling in pressure overload mice.
Topics: Angiotensin II; Animals; Antibodies; Benzhydryl Compounds; Blood Pressure; Cardiomegaly; Chemokine CCL2; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibrosis; HSP70 Heat-Shock Proteins; Hypertension; Male; Mice; Mice, Inbred ICR; Myocardium; p38 Mitogen-Activated Protein Kinases; Protein Transport; Pyrrolidinones; Signal Transduction; Time Factors; Toll-Like Receptor 4; Transcription, Genetic; Transforming Growth Factor beta1; Ventricular Remodeling | 2010 |
A new approach to assessing the structural total peripheral resistance amplifier in renal (Page) hypertension in conscious rabbits.
Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Blood Vessels; Cellophane; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ganglionic Blockers; Hypertension, Renal; Male; Methoxamine; Rabbits; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2010 |
Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction.
Topics: Amides; Angiotensin II; Animals; Base Sequence; Cell Transdifferentiation; Chlorocebus aethiops; Collagen; Collagen Type I; COS Cells; Disease Models, Animal; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Male; Mice; Mice, Knockout; Molecular Sequence Data; Myocardial Infarction; Myocardium; Myocytes, Smooth Muscle; Phenotype; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Transforming Growth Factor beta1; Ventricular Remodeling | 2010 |
Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension.
Topics: Administration, Oral; Adoptive Transfer; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Genes, T-Cell Receptor alpha; Genes, T-Cell Receptor beta; Homeodomain Proteins; Hydralazine; Hypertension; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Norepinephrine; Receptors, Antigen, T-Cell, alpha-beta; Superoxides; T-Lymphocytes; Third Ventricle; Time Factors; Vasculitis | 2010 |
The IP3 receptor regulates cardiac hypertrophy in response to select stimuli.
Topics: Age Factors; Angiotensin II; Animals; Arrhythmias, Cardiac; Calcineurin; Calcium Signaling; Cardiomegaly; Disease Models, Animal; Endothelin-1; GTP-Binding Protein alpha Subunits, Gq-G11; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; Phenotype; Physical Exertion | 2010 |
Inflammation and neurogenic hypertension: a new role for the circumventricular organs?
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Lymphocyte Activation; Mice; Norepinephrine; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes; Third Ventricle; Vasculitis | 2010 |
Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cerebral Arterial Diseases; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitroprusside; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Superoxides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2010 |
Coronary vascular dysfunction promoted by oxidative-nitrative stress in SHRSP.Z-Lepr(fa) /IzmDmcr rats with metabolic syndrome.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Vessels; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Insulin; Lipids; Metabolic Syndrome; Nitric Oxide; Nitroprusside; Oxidative Stress; Rats; Rats, Inbred Strains; Vasodilation | 2010 |
Renal autoregulation and passive pressure-flow relationships in diabetes and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Female; Homeostasis; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; Nephrons; Papaverine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renin; Streptozocin; Vasodilator Agents | 2010 |
[Effect of angiotensin II on the expression of aquaporin 1 in lung of rats following acute lung injury].
Topics: Acute Lung Injury; Angiotensin II; Animals; Aquaporin 1; Disease Models, Animal; Lung; Rats; Rats, Sprague-Dawley | 2010 |
Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats.
Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Down-Regulation; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fumarates; Hypertension; Kidney; Losartan; Male; Mice; Pilot Projects; Radioimmunoassay; Rats; Rats, Transgenic; Renin; Time Factors | 2010 |
Persistent antihypertensive effect of aliskiren is accompanied by reduced proteinuria and normalization of glomerular area in Ren-2 transgenic rats.
Topics: Amides; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fumarates; Heart Rate; Hypertension; Kidney Glomerulus; Losartan; Male; Proteinuria; Rats; Rats, Transgenic; Renin; Time Factors | 2010 |
Hyperglycemia limits experimental aortic aneurysm progression.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Hypoglycemic Agents; Insulin; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Pancreatic Elastase; Peritonitis; Thioglycolates; Time Factors; Ultrasonography; Vascular Endothelial Growth Factor A | 2010 |
Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase.
Topics: Albuminuria; Angiotensin II; Animals; Antioxidants; Bilirubin; Biliverdine; Blood Glucose; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Endothelial Cells; Glomerular Mesangium; Glucose; Humans; Hyperbilirubinemia, Hereditary; Male; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Rats; Rats, Gunn; Superoxides; Time Factors; Transforming Growth Factor beta1 | 2010 |
Adenoviral inhibition of AT1a receptors in the paraventricular nucleus inhibits acute increases in mean arterial blood pressure in the rat.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Transfer Techniques; Genetic Vectors; Heart Rate; Hypertension; Male; Microinjections; Muscle, Smooth, Vascular; Paraventricular Hypothalamic Nucleus; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering; Telemetry; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2010 |
Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockade.
Topics: Albuminuria; Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Kidney; Kidney Glomerulus; Male; Podocytes; Rats; Rats, Long-Evans; Remission Induction; Sclerosis; Treatment Outcome | 2010 |
Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Cardiovascular Diseases; Cell Communication; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Female; Humans; Inflammation Mediators; Male; NF-kappa B; Ovariectomy; PPAR gamma; Rats; Rats, Sprague-Dawley; Resveratrol; Stereoisomerism; Stilbenes; Up-Regulation | 2010 |
Salt-induced cardiac hypertrophy and interstitial fibrosis are due to a blood pressure-independent mechanism in Wistar rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Collagen Type I; Collagen Type III; Disease Models, Animal; Drinking; Eating; Echocardiography; Fibrosis; Gene Expression; Heart Ventricles; Hydralazine; Hypertension; Losartan; Male; Myocardium; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Transforming Growth Factor beta; Urine | 2010 |
Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in rats.
Topics: Adenoviridae; Angiotensin II; Animals; Animals, Genetically Modified; Apoptosis; Capillaries; Cell Proliferation; Disease Models, Animal; Fibrosis; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Heart Failure, Diastolic; Humans; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Rats; Recombinant Proteins; RNA, Messenger; Vascular Endothelial Growth Factor B | 2011 |
Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model.
Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chronic Disease; Desoxycorticosterone; Disease Models, Animal; Disease Progression; Fibrosis; Genetic Predisposition to Disease; Glomerulonephritis; Heart Diseases; Hydralazine; Hypertension; Imidazoles; Infusion Pumps, Implantable; Infusions, Subcutaneous; Kidney; Kidney Diseases; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Nephrectomy; Sodium Chloride, Dietary; Species Specificity; Telemetry; Tetrazoles; Time Factors; X-Ray Microtomography | 2010 |
The renin-angiotensin system and hypertension in autosomal recessive polycystic kidney disease.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Hypertension; Kidney; Male; Mutation; Peptidyl-Dipeptidase A; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Time Factors | 2010 |
Gene silencing of myofibrillogenesis regulator-1 by adenovirus-delivered small interfering RNA suppresses cardiac hypertrophy induced by angiotensin II in mice.
Topics: Adenoviridae; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Extracellular Matrix; Gene Silencing; Gene Transfer Techniques; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Muscle Proteins; RNA, Small Interfering; Signal Transduction; Tissue Inhibitor of Metalloproteinase-2 | 2010 |
Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure.
Topics: Angiotensin II; Angiotensinogen; Animals; bcl-2-Associated X Protein; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Heart; Heart Failure; Heart Rate; Humans; Hydrazones; Hypertension; Major Histocompatibility Complex; Male; Pyridazines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Simendan | 2010 |
Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Angiotensin II; Animals; Blotting, Western; Chronic Disease; Cyclosporine; Deoxyguanosine; Disease Models, Animal; Glucuronidase; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Diseases; Klotho Proteins; Male; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Vasoconstrictor Agents | 2011 |
Cardiac angiotensin II: does it have a function?
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart; Hypertension; Mice; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Ventricular Remodeling | 2010 |
Local angiotensin II aggravates cardiac remodeling in hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Collagen; Desoxycorticosterone; Dinoprost; Disease Models, Animal; Heart Rate; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, Transgenic; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2010 |
Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension.
Topics: Adiponectin; Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Genetic Therapy; Genetic Vectors; HEK293 Cells; Heme Oxygenase-1; Humans; Hypertension; Inflammation; Kidney; Lentivirus; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Vasodilation | 2011 |
Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy.
Topics: Age Factors; Aging; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomyopathies; Collagen; Coronary Circulation; Disease Models, Animal; Echocardiography; Elasticity; Enzyme Inhibitors; Extracellular Matrix; Female; Gene Expression Profiling; Gene Expression Regulation; Genotype; Heart Ventricles; Hemodynamics; Hypertension; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Microscopy, Electron; Microscopy, Video; Myocardium; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenotype; Polymerase Chain Reaction; RNA, Messenger; Telemetry; Ventricular Remodeling | 2010 |
Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Proliferation; Cells, Cultured; CSK Tyrosine-Protein Kinase; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Free Radical Scavengers; Hyperplasia; Hypertension; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; src-Family Kinases; Superoxides | 2010 |
Cigarette smoke enhances abdominal aortic aneurysm formation in angiotensin II-treated apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Body Weight; Disease Models, Animal; Male; Matrix Metalloproteinases; Mice; Nicotiana; Smoke; Tissue Inhibitor of Metalloproteinases | 2010 |
Retinoic acid receptor-mediated signaling protects cardiomyocytes from hyperglycemia induced apoptosis: role of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Apoptosis; Blood Glucose; Cells, Cultured; Diabetes Mellitus; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hyperglycemia; Hypoglycemic Agents; Male; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Zucker; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Retinoic Acid; Renin-Angiotensin System; Retinoic Acid Receptor alpha; Retinoid X Receptor alpha; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors; Tretinoin | 2011 |
Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sleep Apnea Syndromes | 2011 |
Renoprotective effect of Tanshinone IIA, an active component of Salvia miltiorrhiza, on rats with chronic kidney disease.
Topics: Abietanes; Administration, Oral; Angiotensin II; Animals; Collagen Type IV; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Kidney; Male; Phenanthrenes; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Salvia miltiorrhiza; Transforming Growth Factor beta1 | 2010 |
Role of blood flow in carotid body chemoreflex function in heart failure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Flow Velocity; Cardiac Pacing, Artificial; Carotid Arteries; Carotid Body; Chemoreceptor Cells; Constriction; Disease Models, Animal; Heart Failure; Kidney; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Potassium; Rabbits; Receptor, Angiotensin, Type 1; Reflex; Regional Blood Flow; Spectrometry, Fluorescence; Sympathetic Nervous System; Time Factors; Ventricular Function, Left | 2011 |
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acids; Benzoates; Blood Pressure; Cytochrome P-450 CYP1A1; Disease Models, Animal; Enzyme Inhibitors; Epoxide Hydrolases; Glomerular Filtration Rate; Hydroxyeicosatetraenoic Acids; Hypertension; Kidney; Male; Mice; Promoter Regions, Genetic; Proteinuria; Rats; Renal Plasma Flow; Renin; Sodium; Time Factors; Urea | 2011 |
The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Culture Techniques; Cell Line; Disease Models, Animal; Endothelin-1; Humans; Myoblasts, Cardiac; Myocytes, Cardiac; Rats | 2011 |
[Value of in vivo monitoring of abdominal aortic atherosclerosis by high field magnetic resonance imaging in apoE-/- mice fed a high fat diet or infused with angiotensin II].
Topics: Angiotensin II; Animals; Aorta, Abdominal; Apolipoproteins E; Arteriosclerosis; Diet; Dietary Fats; Disease Models, Animal; Magnetic Resonance Imaging; Male; Mice; Mice, Knockout | 2010 |
Supramolecular interactions between losartan and hydroxypropyl-β-CD: ESI mass-spectrometry, NMR techniques, phase solubility, isothermal titration calorimetry and anti-hypertensive studies.
Topics: Administration, Oral; alpha-Cyclodextrins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Calorimetry; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Carriers; Drug Compounding; Hypertension; Kinetics; Losartan; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Solubility; Spectrometry, Mass, Electrospray Ionization; Technology, Pharmaceutical | 2011 |
High density lipoprotein downregulates angiotensin II type 1 receptor and inhibits angiotensin II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Down-Regulation; Lipoproteins, HDL; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Receptor, Angiotensin, Type 1 | 2011 |
Critical roles of macrophages in the formation of intracranial aneurysm.
Topics: Angiotensin II; Animals; Chemokine CCL2; Disease Models, Animal; Female; Humans; Intracranial Aneurysm; Macrophages; Male; Matrix Metalloproteinase 12; Mice; Mice, Knockout; Pancreatic Elastase; Vasoconstrictor Agents | 2011 |
Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Female; Hypertension; Infusions, Subcutaneous; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1 | 2011 |
Adventitia-derived hydrogen peroxide impairs relaxation of the rat carotid artery via smooth muscle cell p38 mitogen-activated protein kinase.
Topics: Angiotensin II; Animals; Carotid Arteries; Catalase; Connective Tissue; Disease Models, Animal; Hydrogen Peroxide; Imidazoles; Male; Muscle Relaxation; Myocytes, Smooth Muscle; Myography; p38 Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyridines; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vascular Diseases | 2011 |
[Effect of Chrysanthemum indicum on ventricular remodeling in rats].
Topics: Aldosterone; Angiotensin II; Animals; Chrysanthemum; Disease Models, Animal; Drugs, Chinese Herbal; Heart Ventricles; Hypertrophy, Left Ventricular; Immunohistochemistry; Isoproterenol; Male; Mice; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; Thyroxine; Tumor Necrosis Factor-alpha; Ventricular Function, Left; Ventricular Remodeling | 2010 |
Impairment of cardiac function and remodeling induced by myocardial infarction in rats are attenuated by the nonpeptide angiotensin-(1-7) analog AVE 0991.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiotonic Agents; Collagen; Disease Models, Animal; Hemodynamics; Imidazoles; Male; Myocardial Contraction; Myocardial Infarction; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Stroke Volume; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Ventricular Function, Left; Ventricular Remodeling | 2012 |
Gene expression, function and ischemia tolerance in male and female rat hearts after sub-toxic levels of angiotensin II.
Topics: Angiotensin II; Animals; Apoptosis; Collagen; Disease Models, Animal; Female; Fibrosis; Gene Expression Regulation; Infusion Pumps, Implantable; Infusions, Subcutaneous; Male; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred BN; Rats, Inbred F344; Recovery of Function; Sex Factors; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2011 |
[Protective effects of captopril against lung injury in rats with severe acute pancreatitis].
Topics: Amylases; Angiotensin II; Animals; Captopril; Disease Models, Animal; Lung; Lung Injury; Male; Pancreatitis; Peroxidase; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2010 |
Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7.
Topics: Adenoviridae; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Cyclin D2; Disease Models, Animal; Mice; Mice, Transgenic; MicroRNAs; Myocytes, Cardiac; Rats; Rats, Wistar; Signal Transduction; Thioredoxins; Up-Regulation | 2011 |
Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renovascular; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Collecting; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin; RNA, Messenger | 2011 |
1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.
Topics: Adamantane; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Disease Models, Animal; Enzyme Inhibitors; Epoxide Hydrolases; Hypertension; Insulin Resistance; Mice; Obesity; Rats; Urea | 2011 |
Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Atherosclerosis; Bone Marrow Cells; Bone Marrow Transplantation; Cell Adhesion; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Cytokines; Dietary Fats; Disease Models, Animal; Endothelial Cells; Humans; Inflammation Mediators; Losartan; Macrophages; Male; Mice; Mice, Knockout; Monocytes; Peptide Fragments; Peptidyl-Dipeptidase A; Receptors, LDL | 2011 |
Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Autoradiography; Contrast Media; Disease Models, Animal; Female; Flow Cytometry; Fluorodeoxyglucose F18; Macrophages; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Reproducibility of Results; Splenectomy; Time Factors; X-Ray Microtomography | 2011 |
Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Cell Communication; Disease Models, Animal; Endothelial Cells; Macrophages; Mice; Mice, Knockout; Mice, Mutant Strains; Mutation; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1; Receptors, LDL | 2011 |
TRPC6 enhances angiotensin II-induced albuminuria.
Topics: Albuminuria; Angiotensin II; Animals; Calcium; Disease Models, Animal; Hypertension; Injections, Subcutaneous; Kidney; Male; Mice; Mice, Knockout; Patch-Clamp Techniques; Podocytes; TRPC Cation Channels; TRPC6 Cation Channel | 2011 |
Vasculoprotective effects of rosiglitazone through modulating renin-angiotensin system in vivo and vitro.
Topics: Angiotensin II; Animals; Aortic Diseases; Atherosclerosis; Blotting, Western; Cardiovascular Agents; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Hypercholesterolemia; Immunohistochemistry; Lipids; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Radioimmunoassay; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Time Factors | 2011 |
Therapeutic effects of continuous infusion of brain natriuretic peptides on postmyocardial infarction ventricular remodelling in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Agents; Collagen; Cyclic GMP; Disease Models, Animal; Enalapril; Hemodynamics; I-kappa B Proteins; Inflammation Mediators; Infusion Pumps, Implantable; Infusions, Intravenous; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardium; Natriuretic Peptide, Brain; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Phosphorylation; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transcription Factor RelA; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Addition of angiotensin II type 1 receptor blocker to CCR2 antagonist markedly attenuates crescentic glomerulonephritis.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Glomerular Basement Membrane Disease; Blood Pressure; Cell Proliferation; Chemokine CCL2; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Kidney; Macrophages; Male; Rats; Rats, Inbred WKY; Receptors, CCR2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta1 | 2011 |
The cardiovascular mighty mini-ruler.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Carotid Arteries; Carotid Body; Disease Models, Animal; Heart Failure; Hypoxia; Nitric Oxide; Nitric Oxide Synthase Type III; Physical Conditioning, Animal; Rabbits; Reactive Oxygen Species; Regional Blood Flow; Sympathetic Nervous System | 2011 |
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomyopathy, Dilated; Disease Models, Animal; Enzyme Activation; Extracellular Matrix; Heart Failure; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Stress, Mechanical; Superoxides; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Involvement of vascular peroxidase 1 in angiotensin II-induced vascular smooth muscle cell proliferation.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix Proteins; Free Radical Scavengers; Hydrogen Peroxide; Hypertension; Hypochlorous Acid; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Peroxidase; Peroxidasin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors | 2011 |
Restriction of big hearts by a small RNA.
Topics: Angiotensin II; Animals; Cardiomegaly; Cyclin D2; Disease Models, Animal; Mice; MicroRNAs; Oxidation-Reduction; Signal Transduction; Thioredoxins | 2011 |
Intrarenal transfer of an intracellular fluorescent fusion of angiotensin II selectively in proximal tubules increases blood pressure in rats and mice.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cells, Cultured; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Hypertension; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Natriuresis; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Time Factors; Transduction, Genetic; Transfection; Up-Regulation; Urination | 2011 |
Pivotal role of protein kinase Cdelta in angiotensin II-induced endothelial cyclooxygenase-2 expression: a link to vascular inflammation.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Blotting, Western; Cells, Cultured; Chemokine CCL2; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Inflammation; Inflammation Mediators; Male; Mesenteric Arteries; Middle Aged; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; RNA Interference; Signal Transduction; Time Factors; Tissue Culture Techniques; Up-Regulation | 2011 |
Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Animals, Newborn; Apolipoproteins E; Bone Marrow Cells; Bone Marrow Transplantation; Cardiomegaly; Cell Communication; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclophilin A; Disease Models, Animal; Fibroblasts; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recombinant Proteins; Time Factors | 2011 |
Renin angiotensin system and cardiac hypertrophy after sinoaortic denervation in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carotid Sinus; Collagen; Denervation; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Renin-Angiotensin System | 2010 |
c-Src in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Capsaicin; CSK Tyrosine-Protein Kinase; Disease Models, Animal; Hypertension, Renovascular; Indoles; Male; NADPH Oxidases; Neurons, Afferent; Paraventricular Hypothalamic Nucleus; Protein-Tyrosine Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reflex; src-Family Kinases; Sulfonamides; Superoxides; Sympathetic Nervous System | 2011 |
Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Hydrogen Peroxide; Hypertension; Janus Kinase 2; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; rho-Associated Kinases; Time Factors; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2011 |
Direct renin inhibition with aliskiren normalizes blood pressure in Cyp1a1-Ren2 transgenic rats with inducible angiotensin ii-dependent malignant hypertension.
Topics: Amides; Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP1A1; Disease Models, Animal; Fumarates; Glomerular Filtration Rate; Hypertension, Malignant; Kidney; Male; Rats; Rats, Transgenic; Regional Blood Flow; Renin; Vascular Resistance | 2011 |
Trapping intracellular ANG II to the proximal tubule: powerful in vivo effects on sodium handling and blood pressure.
Topics: Adenoviridae; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Hypertension; Kidney Tubules, Proximal; Mice; Natriuresis; Rats; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Transduction, Genetic; Up-Regulation; Urination | 2011 |
Parsing aortic aneurysms: more surprises.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cell Communication; Disease Models, Animal; Endothelial Cells; Incidence; Macrophages; Mice; Mice, Knockout; Mice, Mutant Strains; Mutation; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1; Receptors, LDL | 2011 |
Effect of myricetin on deoxycorticosterone acetate (DOCA)-salt-hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Catalase; Desoxycorticosterone; Disease Models, Animal; Female; Flavonoids; Glutathione; Heart Rate; Hypertension; Oxidative Stress; Rats; Rats, Wistar; Serotonin; Sodium Chloride; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitaceae | 2011 |
Icariin attenuates cardiac remodelling through down-regulating myocardial apoptosis and matrix metalloproteinase activity in rats with congestive heart failure.
Topics: Angiotensin II; Animals; Apoptosis; Cardiotonic Agents; Disease Models, Animal; Down-Regulation; Flavonoids; Heart Failure; Hemodynamics; Isoproterenol; Male; Matrix Metalloproteinases; Mitochondria; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Norepinephrine; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2011 |
Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Antihypertensive Agents; Antioxidants; Apoptosis; Cardiomyopathies; Caspase 3; Cells, Cultured; Collagen Type I; Disease Models, Animal; Enzyme Activation; Fibrosis; Heme Oxygenase (Decyclizing); Hemin; Hemodynamics; Hypertension, Renovascular; Losartan; Male; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; Rats; Rats, Wistar; rhoA GTP-Binding Protein; Signal Transduction; Time Factors; Ventricular Function, Left | 2011 |
A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Arachidonate 5-Lipoxygenase; Cardiotonic Agents; Cardiovascular System; Cell Line; Cyclooxygenase Inhibitors; Disease Models, Animal; Epoxide Hydrolases; Injections, Subcutaneous; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-E Synthases; Pyrimidines | 2011 |
Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice.
Topics: Actins; Angiotensin II; Animals; Apoptosis; Cell Movement; Cell Proliferation; Cell Survival; Disease Models, Animal; Female; Fibrosis; Janus Kinase 2; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Neointima; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Vascular System Injuries | 2011 |
Improved cardiac function after sarcoplasmic reticulum Ca(2+)-ATPase gene transfer in a heart failure model induced by chronic myocardial ischaemia.
Topics: Adenoviridae; Angiotensin II; Animals; Disease Models, Animal; Endothelin-1; Fluorescent Dyes; Gene Transfer Techniques; Genetic Therapy; Green Fluorescent Proteins; Heart Failure; Interleukin-6; Male; Myocardial Infarction; Myocardium; Natriuretic Peptide, Brain; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stroke Volume; Swine; Swine, Miniature; Tumor Necrosis Factor-alpha | 2011 |
Autonomic control of the heart is altered in Sprague-Dawley rats with spontaneous hydronephrosis.
Topics: Angiotensin II; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Disease Models, Animal; Heart; Heart Rate; Hydronephrosis; Kidney Medulla; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2011 |
Inward remodeling of resistance arteries requires reactive oxygen species-dependent activation of matrix metalloproteinases.
Topics: Angiotensin II; Animals; Arterioles; Disease Models, Animal; Hypertension; Male; Matrix Metalloproteinases; Norepinephrine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Resistance; Vasoconstriction | 2011 |
Effect of pregnancy and diabetes on vascular receptors for angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes, Gestational; Disease Models, Animal; Endothelium, Vascular; Female; Hypertension; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Risk Factors; Streptozocin; Vasoconstriction | 2011 |
Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice.
Topics: Aged; Angiotensin II; Animals; Antibodies, Neutralizing; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Cells, Cultured; Dendritic Cells; Dietary Fats; Disease Models, Animal; Female; Humans; Inflammation; Interferon-gamma; Interleukin-17; Ligation; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Nitric Oxide; Spleen; Superoxides; Time Factors | 2011 |
Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Disease Models, Animal; Disease Progression; Enalapril; Losartan; MAP Kinase Signaling System; Marfan Syndrome; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, Angiotensin, Type 2; Signal Transduction; Transforming Growth Factor beta | 2011 |
Exacerbation of thrombotic events by diesel exhaust particle in mouse model of hypertension.
Topics: Air Pollutants; Angiotensin II; Animals; Blood Platelets; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Mice; Oxygen; Partial Thromboplastin Time; Particulate Matter; Platelet Aggregation; Prothrombin Time; Thrombosis; Vehicle Emissions | 2011 |
An ethanolic extract of Lindera obtusiloba stems causes NO-mediated endothelium-dependent relaxations in rat aortic rings and prevents angiotensin II-induced hypertension and endothelial dysfunction in rats.
Topics: Angiotensin II; Animals; Aorta; Cattle; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Ethanol; Hypertension; Lindera; Male; Medicine, East Asian Traditional; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Extracts; Plant Stems; Rats; Rats, Sprague-Dawley | 2011 |
Catalase overexpression in aortic smooth muscle prevents pathological mechanical changes underlying abdominal aortic aneurysm formation.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Blood Pressure; Catalase; Collagen; Disease Models, Animal; Elastin; Hydrogen Peroxide; Mice; Mice, Knockout; Mice, Transgenic; Stress, Mechanical; Time Factors; Up-Regulation | 2011 |
Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Connexin 43; Disease Models, Animal; Electrocardiography; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Phosphorylation; Renin-Angiotensin System; Risk; Tachycardia, Ventricular | 2011 |
Intramyocardial BNP gene delivery improves cardiac function through distinct context-dependent mechanisms.
Topics: Adenoviridae; Angiotensin II; Animals; Collagen Type III; Disease Models, Animal; Fibrosis; Gene Transfer Techniques; Genetic Therapy; Humans; Hypertension; Ligation; Male; Myocardial Infarction; Natriuretic Peptide, Brain; Neovascularization, Physiologic; Organothiophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Dysfunction, Left; Ventricular Remodeling | 2011 |
CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis.
Topics: Analysis of Variance; Angiotensin II; Animals; Biomarkers; Blood Pressure; Bone Marrow Cells; Cardiomegaly; Cell Movement; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Diseases; Heart Rate; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptors, CCR2; Stem Cells; Stroke Volume; Time Factors; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Elevated expression of connective tissue growth factor in human atrial fibrillation and angiotensin II-treated cardiomyocytes.
Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Atrial Fibrillation; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Disease Models, Animal; Extracellular Matrix; Female; Fibroblasts; Heart Atria; Humans; Male; Middle Aged; Myocytes, Cardiac; Rats; Rats, Wistar; RNA, Messenger; Swine | 2011 |
Angiotensin-converting enzyme inhibition augments the expression of rat elastase-2, an angiotensin II-forming enzyme.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Disease Models, Animal; Enalapril; Hypertension; Immunohistochemistry; Male; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; Rats, Wistar; RNA, Messenger; Serine Endopeptidases; Time Factors; Up-Regulation; Vasoconstriction | 2011 |
Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fibrinolysin; Fibrosis; Glomerulonephritis; Heart Diseases; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Plasminogen; Plasminogen Activator Inhibitor 1; Prevalence; Risk Factors; Tissue Plasminogen Activator | 2011 |
Effects of losartan, in monotherapy or in association with hydrochlorothiazide, in chronic nephropathy resulting from losartan treatment during lactation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Blood Pressure; Chronic Disease; Disease Models, Animal; Diuretics; Drug Therapy, Combination; Female; Hydrochlorothiazide; Kidney; Kidney Diseases; Lactation; Losartan; Male; Nephrons; Rats; Rats, Inbred Strains | 2011 |
Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling.
Topics: Adiponectin; AMP-Activated Protein Kinases; Analysis of Variance; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Genes, Reporter; Hydrogen Peroxide; Hypertrophy, Left Ventricular; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; NADPH Oxidases; Natriuretic Peptide, Brain; NF-kappa B; Oxidants; Oxidative Stress; Phosphorylation; Rats; Reactive Oxygen Species; Recombinant Proteins; RNA, Messenger; Signal Transduction; Time Factors; Transfection; Ventricular Remodeling | 2011 |
Effects of chronic dietary salt loading on the renin angiotensin and adrenergic systems of rainbow trout (Oncorhynchus mykiss).
Topics: Adrenergic alpha-Antagonists; Adrenergic Fibers; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Chromaffin Cells; Disease Models, Animal; Epinephrine; Female; Hypertension; Hypotension; Hypoxia; Male; Norepinephrine; Oncorhynchus mykiss; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2011 |
Role of angiotensin-(1-7) in rostral ventrolateral medulla in blood pressure regulation via sympathetic nerve activity in Wistar-Kyoto and spontaneous hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan | 2011 |
Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin.
Topics: Angiotensin II; Animals; Cholesterol; Disease Models, Animal; Doxorubicin; Endothelin-1; Fluorescent Antibody Technique; Inflammation; Inflammation Mediators; Kidney; Losartan; Male; Nephrosis; Proteinuria; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides; Weight Gain | 2011 |
Novel mechanism of salt-induced glomerular injury: critical role of eNOS and angiotensin II.
Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Glomerulonephritis; Irbesartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Sodium Chloride, Dietary; Spin Labels; Tetrazoles | 2011 |
Experimental depression induces renal oxidative stress in rats.
Topics: Angiotensin II; Animals; Depression; Disease Models, Animal; Glutathione; Kidney; Macrophages; Male; Malondialdehyde; Monocytes; Motor Activity; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Swimming; Time Factors | 2011 |
Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation.
Topics: Actins; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Becaplermin; Binding Sites; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Cells, Cultured; Chromatin Immunoprecipitation; Coculture Techniques; Computational Biology; Disease Models, Animal; Gene Expression Regulation; Genes, Reporter; Humans; Hyperplasia; Introns; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NFATC Transcription Factors; Phenotype; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein Transport; Proto-Oncogene Proteins c-sis; Rats; RNA Interference; RNA, Messenger; Transcription Factors; Transfection; Tunica Intima | 2011 |
Aorta from angiotensin II hypertensive mice exhibit preserved nitroxyl anion mediated relaxation responses.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Free Radical Scavengers; Guanylate Cyclase; Hypertension; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrites; Nitrogen Oxides; Potassium Channel Blockers; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2012 |
Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failure.
Topics: Angiotensin II; Animals; Cell Nucleus; Cytoplasm; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 5; Green Fluorescent Proteins; GTP-Binding Protein alpha Subunits, Gq-G11; Heart Failure; Histone Deacetylases; Humans; Mice; Mice, Knockout; Mice, Transgenic; Phosphorylation; Sequence Analysis, RNA; Transcription, Genetic | 2011 |
Azelnidipine is a calcium blocker that attenuates liver fibrosis and may increase antioxidant defence.
Topics: Angiotensin II; Animals; Antioxidants; Azetidinecarboxylic Acid; Calcium; Calcium Channel Blockers; Carbon Tetrachloride; Cell Line; Cell Survival; Collagen Type I; Collagen Type I, alpha 1 Chain; Dihydropyridines; Disease Models, Animal; Gene Expression Regulation; Humans; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; RNA, Messenger; Thioacetamide; Transforming Growth Factor beta1 | 2012 |
Activation of the renin-angiotensin system in hyperoxia-induced lung fibrosis in neonatal rats.
Topics: Angiotensin II; Animals; Animals, Newborn; Biomarkers; Collagen Type I; Disease Models, Animal; Gene Expression Regulation, Developmental; Hyperoxia; Lung; MAP Kinase Signaling System; Oxygen; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2012 |
Mechanisms mediating sodium-induced pressor responses in the PVN of Dahl rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Hypertension; Infusions, Intraventricular; Male; Mineralocorticoid Receptor Antagonists; Neurons; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Dahl; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Signal Transduction; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium Chloride, Dietary; Time Factors | 2011 |
Angiotensin II utilizes Janus kinase 2 in hypertension, but not in the physiological control of blood pressure, during low-salt intake.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, Sodium-Restricted; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension; Infusions, Intravenous; Janus Kinase 2; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Tyrphostins | 2011 |
Interleukin-10 released by CD4(+)CD25(+) natural regulatory T cells improves microvascular endothelial function through inhibition of NADPH oxidase activity in hypertensive mice.
Topics: Acetylcholine; Angiotensin II; Animals; CD4 Antigens; Cell- and Tissue-Based Therapy; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Hypertension; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microvessels; NADPH Oxidases; T-Lymphocytes, Regulatory; Vasodilation; Vasodilator Agents | 2011 |
Decreased nNOS in the PVN leads to increased sympathoexcitation in chronic heart failure: role for CAPON and Ang II.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line, Tumor; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Heart Failure; Hemodynamics; Immunohistochemistry; Kidney; Losartan; Male; Microinjections; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, N-Methyl-D-Aspartate; RNA Interference; RNA, Messenger; Sympathetic Nervous System; Time Factors | 2011 |
Central angiotensin (1-7) enhances baroreflex gain in conscious rabbits with heart failure.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Chronic Disease; Consciousness; Disease Models, Animal; Heart Failure; Heart Rate; Infusions, Intraventricular; Kidney; Male; Metoprolol; Peptide Fragments; Rabbits; Sympathetic Nervous System; Vagus Nerve | 2011 |
Urokinase-type plasminogen activator deficiency in bone marrow-derived cells augments rupture of angiotensin II-induced abdominal aortic aneurysms.
Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bone Marrow Cells; Disease Models, Animal; Hypercholesterolemia; Incidence; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL; Receptors, Urokinase Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2011 |
Early life stress enhances angiotensin II-mediated vasoconstriction by reduced endothelial nitric oxide buffering capacity.
Topics: Angiotensin II; Animals; Animals, Newborn; Aorta, Thoracic; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; Maternal Deprivation; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Signal Transduction; Stress, Physiological; Vasoconstriction | 2011 |
Silencing of hypoxia-inducible factor-1α gene attenuated angiotensin II-induced renal injury in Sprague-Dawley rats.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Chronic Disease; Creatinine; Disease Models, Animal; Gene Expression Regulation; Gene Silencing; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Diseases; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Vascular Endothelial Growth Factor A | 2011 |
Blood pressure and renal hemodynamic responses to acute angiotensin II infusion are enhanced in a female mouse model of systemic lupus erythematosus.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Female; Hypertension; Infusions, Intra-Arterial; Kidney; Losartan; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; RNA, Messenger; Vascular Resistance; Vasoconstriction | 2011 |
Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm.
Topics: Acute-Phase Proteins; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Collagen; Decorin; Disease Models, Animal; Granzymes; Mice; Mice, Knockout; Protein Processing, Post-Translational; Recombinant Proteins; Serpins | 2011 |
MicroRNA-29 in aortic dilation: implications for aneurysm formation.
Topics: Aging; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Biopsy; Dilatation, Pathologic; Disease Models, Animal; Extracellular Matrix Proteins; Gene Expression Profiling; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Mutation; Oligoribonucleotides, Antisense | 2011 |
Mesenchymal stem cells attenuate angiotensin II-induced aortic aneurysm growth in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Apolipoproteins E; Cell Culture Techniques; Coculture Techniques; Disease Models, Animal; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Vasoconstrictor Agents | 2011 |
Role of T lymphocytes in angiotensin II-mediated microvascular thrombosis.
Topics: Adoptive Transfer; Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Female; Hypertension; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; NADPH Oxidases; Random Allocation; Reactive Oxygen Species; Sensitivity and Specificity; T-Lymphocytes; Thrombosis | 2011 |
Vascular hyporeactivity to angiotensin II and noradrenaline in a rabbit model of obesity.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Glucose; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Glucose Tolerance Test; In Vitro Techniques; Insulin; Isometric Contraction; Lipids; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nitrites; Norepinephrine; Obesity; Rabbits; Vasodilation | 2012 |
Losartan improves aortic endothelium-dependent relaxation via proline-rich tyrosine kinase 2/Src/Akt pathway in type 2 diabetic Goto-Kakizaki rats.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blotting, Western; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Focal Adhesion Kinase 2; Immunohistochemistry; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Losartan; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; src-Family Kinases; Vasodilation; Vasodilator Agents | 2011 |
Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Humans; Intracellular Signaling Peptides and Proteins; Kidney Failure, Chronic; Kidney Glomerulus; Male; Membrane Proteins; Podocytes; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Rats, Transgenic; RNA, Messenger | 2012 |
Candesartan restored cardiac Hsp72 expression and tolerance against reperfusion injury in hereditary insulin-resistant rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cells, Cultured; Dietary Fats; Disease Models, Animal; Genetic Predisposition to Disease; Glucose Tolerance Test; Glucose Transporter Type 4; Heredity; HSP72 Heat-Shock Proteins; Hyperthermia, Induced; Insulin Resistance; Male; Myocardial Reperfusion Injury; Myocardium; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Recovery of Function; Tetrazoles; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2011 |
ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension.
Topics: Adenoviridae; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Hypertension; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Telemetry; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through Toll-like receptors 2 and 4.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Leukocytes; Male; Mice; Mice, Knockout; Myeloid Differentiation Factor 88; Receptors, LDL; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2011 |
Niaspan enhances vascular remodeling after stroke in type 1 diabetic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Blood-Brain Barrier; Cerebral Hemorrhage; Cerebrovascular Circulation; Cholesterol, HDL; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Niacin; Rats; Rats, Wistar; Vasodilator Agents | 2011 |
Calpain inhibition attenuates angiotensin II-induced abdominal aortic aneurysms and atherosclerosis in low-density lipoprotein receptor-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Blotting, Western; Calpain; Cysteine Proteinase Inhibitors; Diet, High-Fat; Disease Models, Animal; Hypercholesterolemia; Male; Mice; Mice, Knockout; Receptors, LDL; Sulfonamides | 2012 |
Macrophage polarization by angiotensin II-type 1 receptor aggravates renal injury-acceleration of atherosclerosis.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; Cell Polarity; Disease Models, Animal; Female; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Phenotype; Receptor, Angiotensin, Type 1 | 2011 |
Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.
Topics: Actins; Alveolar Epithelial Cells; Angiotensin II; Animals; Antibiotics, Antineoplastic; Benzamides; Bleomycin; Cells, Cultured; Collagen Type I; Dioxoles; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Ligands; Male; Mice; Mice, Knockout; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Vimentin | 2012 |
L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Down-Regulation; Hypertension; Injections, Intravenous; Male; Nifedipine; Rats; Rats, Inbred SHR; Reflex; Renin-Angiotensin System | 2012 |
Blood-borne angiotensin II acts in the brain to influence behavioral and endocrine responses to psychogenic stress.
Topics: Analysis of Variance; Angiotensin II; Animals; Behavior, Animal; Disease Models, Animal; Endocrine System; Green Fluorescent Proteins; Hormones; Male; Phytohemagglutinins; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Stress, Psychological; Subfornical Organ; Time Factors; Transduction, Genetic | 2011 |
Augmented S-nitrosylation contributes to impaired relaxation in angiotensin II hypertensive mouse aorta: role of thioredoxin reductase.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cyclic GMP; Cysteine; Dinitrochlorobenzene; Disease Models, Animal; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Phenylephrine; S-Nitrosothiols; Thioredoxin-Disulfide Reductase; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
High-salt diet increases glomerular ACE/ACE2 ratio leading to oxidative stress and kidney damage.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Kidney Diseases; Kidney Glomerulus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System; Sodium Chloride, Dietary | 2012 |
Influence of myocardial infarction on changes in the expression of angiotensin type 1 receptor in the rat prostate.
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Male; Myocardial Infarction; Prostate; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2011 |
Myocardial performance and its acute response to angiotensin II infusion in fetal sheep adapted to chronic anemia.
Topics: Anemia; Angiotensin II; Animals; Cardiotonic Agents; Disease Models, Animal; Female; Fetal Diseases; Pregnancy; Sheep, Domestic; Vasoconstrictor Agents; Ventricular Function; Ventricular Remodeling | 2012 |
Hyperglycaemia emerging during general anaesthesia induces rat acute kidney injury via impaired microcirculation, augmented apoptosis and inhibited cell proliferation.
Topics: Acute Kidney Injury; Anesthesia, General; Angiotensin II; Animals; Apoptosis; Biomarkers; Blood Glucose; Blood Pressure; Cell Proliferation; Cystatin C; Disease Models, Animal; Glucose; Hyperglycemia; Insulin; Kidney; Microcirculation; Rats; Rats, Sprague-Dawley; Renal Circulation; Time Factors; Urea | 2012 |
Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Female; Fingolimod Hydrochloride; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; NFATC Transcription Factors; p21-Activated Kinases; Propylene Glycols; Rats; Signal Transduction; Sphingosine; Stress, Physiological | 2011 |
Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acid.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Biopterins; Blood Pressure; Disease Models, Animal; Folic Acid; Genetic Therapy; GTP Cyclohydrolase; Hypertension; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Mutant Strains; Nitric Oxide; Nitric Oxide Synthase Type III; Tetrahydrofolate Dehydrogenase; Vasoconstrictor Agents; Vitamin B Complex | 2012 |
Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death.
Topics: Angiotensin II; Animals; Blotting, Western; Connexin 43; CSK Tyrosine-Protein Kinase; Death, Sudden, Cardiac; Disease Models, Animal; Enzyme Inhibitors; Gap Junctions; Immunohistochemistry; Mice; Mice, Transgenic; Phosphorylation; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; src-Family Kinases; Tachycardia, Ventricular; Telemetry; Ventricular Fibrillation | 2011 |
Loss of receptor activity-modifying protein 3 exacerbates cardiac hypertrophy and transition to heart failure in a sex-dependent manner.
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Diseases; Disease Models, Animal; Female; Gene Expression; Gene Expression Profiling; Gene Knockout Techniques; Genetic Association Studies; Heart Failure; Hypertension; Hypertrophy, Right Ventricular; Kidney Diseases; Male; Mice; Mice, Knockout; Phenotype; Proto-Oncogene Proteins c-akt; Receptor Activity-Modifying Protein 3; Renin; Sex Factors | 2012 |
Angiotensin II receptor activation in youth triggers persistent insulin resistance and hypertension--a legacy effect?
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Body Weight; Chemokine CCL2; Disease Models, Animal; Hypertension; Insulin Resistance; Muscle, Skeletal; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Angiotensin; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2012 |
Cooperative interaction between reactive oxygen species and Ca2+ signals contributes to angiotensin II-induced hypertrophy in adult rat cardiomyocytes.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Cells, Cultured; Disease Models, Animal; Down-Regulation; Hypertrophy; Male; Myocytes, Cardiac; NADPH Oxidases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Superoxides | 2012 |
Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Bone Marrow Cells; Bone Marrow Transplantation; Cells, Cultured; Cholesterol; Disease Models, Animal; Hypercholesterolemia; LDL-Receptor Related Protein-Associated Protein; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, LDL; Tumor Suppressor Proteins | 2012 |
Drugs of the future for Peyronie's disease.
Topics: Adult; Angiotensin II; Animals; Connective Tissue Growth Factor; Disease Models, Animal; Drug Design; Drug Therapy; Endothelin-1; Fibrosis; Humans; Inflammation; Male; Middle Aged; Penile Induration; Platelet-Derived Growth Factor; Transforming Growth Factor beta1; Wound Healing | 2012 |
Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice.
Topics: Angiotensin II; Animals; Aryl Hydrocarbon Hydroxylases; Blood Pressure; CSK Tyrosine-Protein Kinase; Cytochrome P-450 CYP1B1; Disease Models, Animal; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Hypertension; Kidney; Male; Mice; Mice, Knockout; NADPH Oxidases; Protein-Tyrosine Kinases; Reactive Oxygen Species; Sodium; src-Family Kinases; Vascular Resistance | 2012 |
p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Reactive Oxygen Species; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2012 |
The effects of angiotensin II on the coupled microstructural and biomechanical response of C57BL/6 mouse aorta.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Collagen; Disease Models, Animal; Extracellular Matrix; Mice; Mice, Inbred C57BL | 2012 |
Increased angiotensin II-induced hypertension and inflammatory cytokines in mice lacking angiotensin-converting enzyme N domain activity.
Topics: Angiotensin II; Animals; Blood Pressure; Cytokines; Disease Models, Animal; Hypertension; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Tumor Necrosis Factor-alpha | 2012 |
Sensitization of slow pressor angiotensin II (Ang II)-initiated hypertension: induction of sensitization by prior Ang II treatment.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger | 2012 |
Fibroblast progenitor cells are recruited into the myocardium prior to the development of myocardial fibrosis.
Topics: AC133 Antigen; Actins; Angiotensin II; Animals; Antigens, CD; Biomarkers; Cell Movement; Cells, Cultured; Chemokine CCL2; Chemokines; Collagen; Disease Models, Animal; Ectodysplasins; Extracellular Matrix; Fibroblasts; Fibrosis; Glycoproteins; Heart; Male; Mesenchymal Stem Cells; Myocardium; Myocytes, Cardiac; Peptides; Rats; Rats, Inbred Lew | 2012 |
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.
Topics: Adolescent; Aged; Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Disease Models, Animal; Disease Progression; Elastin; Gene Expression; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Middle Aged; Pancreatic Elastase; Protein Isoforms; Swine; Young Adult | 2012 |
High dietary salt and angiotensin II chronically increase renal sympathetic nerve activity: a direct telemetric study.
Topics: Action Potentials; Angiotensin II; Animals; Baroreflex; Blood Pressure; Chronic Disease; Disease Models, Animal; Female; Follow-Up Studies; Hypertension; Kidney; Male; Rabbits; Sodium Chloride, Dietary; Sympathetic Nervous System; Telemetry | 2012 |
Pioglitazone ameliorates systolic and diastolic cardiac dysfunction in rat model of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Diastole; Disease Models, Animal; Heart Diseases; Hypertension; Hypoglycemic Agents; Male; Pioglitazone; Rats; Rats, Sprague-Dawley; Systole; Thiazolidinediones | 2013 |
Partial restoration of cardio-vascular defects in a rescued severe model of spinal muscular atrophy.
Topics: Angiotensin II; Animals; Coronary Vessels; Disease Models, Animal; Fibrosis; Genetic Therapy; Heart; Heart Ventricles; Mice; Mice, Knockout; Muscular Atrophy, Spinal; NADPH Oxidases; Oxidative Stress; Receptor, Angiotensin, Type 1; Spinal Cord; Survival of Motor Neuron 1 Protein; Ventricular Remodeling | 2012 |
Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE⁻/⁻ mice.
Topics: Angiotensin II; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Blood Pressure; Chemotaxis; Disease Models, Animal; Disease Progression; Endothelial Cells; Humans; Macrophages; Membrane Glycoproteins; Mice; Mice, Knockout; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidases; Signal Transduction; Superoxides; Time Factors; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2012 |
Role of angiotensin II-mediated AMPK inactivation on obesity-related salt-sensitive hypertension.
Topics: AMP-Activated Protein Kinases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Hypertension; Kidney; Losartan; Metabolic Syndrome; Metformin; Mice; Mice, Inbred C57BL; Obesity; Phosphorylation; Sodium; Sodium, Dietary | 2012 |
A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm, Abdominal; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Lymphocyte Activation; Macrophage Activation; Male; Mice; Mice, Knockout; Peptides; Platelet Endothelial Cell Adhesion Molecule-1; Receptors, Antigen, T-Cell; T-Lymphocytes; Time Factors | 2012 |
Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Blood Pressure; Cardiomegaly; Constriction, Pathologic; Disease Models, Animal; Elastin; Enzyme Activation; Enzyme Inhibitors; Humans; Hypertension; Losartan; Mice; NADPH Oxidases; Oxidative Stress; Sequence Deletion; Williams Syndrome | 2012 |
Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephritis; NF-kappa B; Peptidyl-Dipeptidase A; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta; Ubiquitin-Protein Ligases; Ureteral Obstruction | 2012 |
ET-1 from endothelial cells is required for complete angiotensin II-induced cardiac fibrosis and hypertrophy.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Northern; Blotting, Western; Cardiomegaly; Disease Models, Animal; Endothelial Cells; Endothelin-1; Fibrosis; Gene Expression Regulation; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Polymerase Chain Reaction; Protein Kinase C-delta; Protein Kinase C-epsilon | 2012 |
Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain.
Topics: Angiotensin II; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Hydrazines; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazepines; Reactive Oxygen Species; Receptor Cross-Talk; Receptors, Prostaglandin E, EP1 Subtype; Signal Transduction; Subfornical Organ | 2012 |
Reduction of renal lipid content and proteinuria by a PPAR-γ agonist in a rat model of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Ferritins; Gene Expression Regulation; Heme Oxygenase-1; Hypertension; Iron; Kidney; Lipid Metabolism; Male; Pioglitazone; PPAR gamma; Proteinuria; Rats; Rats, Sprague-Dawley; Thiazolidinediones | 2012 |
Heart angiotensin II-induced cardiomyocyte hypertrophy suppresses coronary angiogenesis and progresses diabetic cardiomyopathy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apoptosis; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Hypertrophy; Hypertrophy, Left Ventricular; Imidazoles; Male; Myocytes, Cardiac; Neovascularization, Physiologic; Olmesartan Medoxomil; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Tetrazoles; Thrombospondin 1; Vascular Endothelial Growth Factor A; Ventricular Dysfunction, Left | 2012 |
Control of hypertension in rats using volatile components of leaves of Taxus chinensis var. mairei.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Chromatography, Supercritical Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Hydrochlorothiazide; Hypertension; Lipids; Male; Nitric Oxide; Nitroarginine; Phytotherapy; Plant Leaves; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Taxus; Time Factors; Volatilization | 2012 |
Antihypertensive effect of long-term oral administration of jellyfish (Rhopilema esculentum) collagen peptides on renovascular hypertension.
Topics: Administration, Oral; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypertension, Renovascular; Kidney; Male; Peptide Fragments; Rats; Rats, Wistar; Scyphozoa; Time Factors | 2012 |
Cardiac remodeling is not modulated by overexpression of muscle LIM protein (MLP).
Topics: Angiotensin II; Animals; Animals, Newborn; Aorta; Blood Pressure; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Genotype; Ligation; LIM Domain Proteins; Mice; Mice, 129 Strain; Mice, Transgenic; Muscle Proteins; Myocardial Contraction; Myocardium; Phenotype; Rats; Rats, Wistar; Ultrasonography; Ventricular Function, Left; Ventricular Remodeling | 2012 |
Angiotensin II- and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation.
Topics: Acute Kidney Injury; Adrenalectomy; Aldosterone; Analysis of Variance; Angiotensin II; Animals; Blotting, Western; Disease Models, Animal; Eplerenone; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; rac1 GTP-Binding Protein; Random Allocation; Real-Time Polymerase Chain Reaction; Receptors, Mineralocorticoid; Signal Transduction; Sodium Chloride, Dietary; Spironolactone; Statistics, Nonparametric | 2012 |
In vivo imaging of macrophages during the early-stages of abdominal aortic aneurysm using high resolution MRI in ApoE mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Cytokines; Dextrans; Disease Models, Animal; Humans; Lipids; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phagocytosis | 2012 |
Angiotensin II-mediated up-regulation of connective tissue growth factor promotes atrial tissue fibrosis in the canine atrial fibrillation model.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Blotting, Western; Connective Tissue Growth Factor; Disease Models, Animal; Dogs; Extracellular Matrix; Female; Heart Atria; Imidazoles; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetrazoles; Up-Regulation | 2012 |
Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.
Topics: Angiotensin II; Animals; Antioxidants; Apoptosis; Boranes; Carbon Dioxide; Carbonates; Catalase; Cells, Cultured; Cytoprotection; Disease Models, Animal; Endothelial Cells; Heme Oxygenase-1; Hemin; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypertension; Hypertrophy; Ischemia; Lung; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Physiologic; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Organometallic Compounds; Oxidative Stress; Polyethylene Glycols; RNA, Messenger; Time Factors; Transfection | 2012 |
Deletion of the angiotensin II type 1a receptor prevents atherosclerotic plaque rupture in apolipoprotein E-/- mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Carotid Artery Diseases; Carotid Artery, Common; CD36 Antigens; Disease Models, Animal; Disease Progression; Focal Adhesion Kinase 1; Gene Deletion; JNK Mitogen-Activated Protein Kinases; Lipids; Lipoproteins, LDL; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 1; Rupture, Spontaneous; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan | 2012 |
Angiotensin converting enzyme 2 contributes to sex differences in the development of obesity hypertension in C57BL/6 mice.
Topics: 3T3-L1 Cells; Adipocytes; Adiposity; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Estrogens; Female; Gene Expression Regulation, Enzymologic; Hypertension; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Progesterone; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Risk Factors; RNA, Messenger; Sex Factors; Testosterone; Time Factors; Weight Gain | 2012 |
Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Flavonoids; Losartan; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phosphorylation; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 2; Signal Transduction; Time Factors; Vasodilation; Vasodilator Agents | 2012 |
Enhanced sensitivity of aged fibrotic hearts to angiotensin II- and hypokalemia-induced early afterdepolarization-mediated ventricular arrhythmias.
Topics: Aging; Angiotensin II; Animals; Arrhythmias, Cardiac; Disease Models, Animal; Fibrosis; Heart; Hypokalemia; Male; Myocardium; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; Patch-Clamp Techniques; Rats; Rats, Inbred F344; Reactive Oxygen Species; Ventricular Fibrillation | 2012 |
Role of heart rate reduction in the prevention of experimental heart failure: comparison between If-channel blockade and β-receptor blockade.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin II; Animals; Apoptosis; Benzazepines; Cyclic Nucleotide-Gated Cation Channels; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Failure; Heart Rate; Immunohistochemistry; In Situ Nick-End Labeling; Ivabradine; Male; Metoprolol; Mice; Mice, Inbred C57BL; Multivariate Analysis; Random Allocation; Sensitivity and Specificity; Statistics, Nonparametric; Tachycardia; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Remodeling | 2012 |
TASK-3 channel deletion in mice recapitulates low-renin essential hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Gene Expression Regulation; Humans; Hyperaldosteronism; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium Channels; Random Allocation; Real-Time Polymerase Chain Reaction; Renin-Angiotensin System; Sensitivity and Specificity; Sequence Deletion; Sodium | 2012 |
Angiotensin II plays a critical role in alcohol-induced cardiac nitrative damage, cell death, remodeling, and cardiomyopathy in a protein kinase C/nicotinamide adenine dinucleotide phosphate oxidase-dependent manner.
Topics: Angiotensin II; Animals; Cardiomyopathy, Alcoholic; Cell Death; Disease Models, Animal; Disease Progression; Ethanol; Heart Ventricles; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NADP; Oxidative Stress; Protein Kinase C; Ventricular Remodeling | 2012 |
Inhibition of development of abdominal aortic aneurysm by glycolysis restriction.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Calcium Chloride; Cell Adhesion; Cell Proliferation; Cell Survival; Deoxyglucose; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Fluorodeoxyglucose F18; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Glycolysis; Humans; Inflammation Mediators; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Positron-Emission Tomography; Radiopharmaceuticals; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells; Up-Regulation | 2012 |
Additive amelioration of oxidative stress and cardiac function by combined mineralocorticoid and angiotensin receptor blockers in postinfarct failing hearts.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; Drug Therapy, Combination; Heart Failure; Hemodynamics; Imidazoles; Lipid Peroxidation; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone; Tetrazoles; Ventricular Function, Left | 2012 |
Remodeling of intramural thrombus and collagen in an Ang-II infusion ApoE-/- model of dissecting aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Apolipoproteins E; Collagen; Disease Models, Animal; Humans; Infusions, Intra-Arterial; Male; Mice; Mice, Knockout; Thrombosis; Vasodilator Agents | 2012 |
Inhibition of EP4 signaling attenuates aortic aneurysm formation.
Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Line; Disease Models, Animal; Enzyme Activation; Female; Gene Deletion; Humans; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mice; Mice, Knockout; Middle Aged; Myocytes, Smooth Muscle; Naphthalenes; Phenylbutyrates; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Tissue Culture Techniques; Up-Regulation | 2012 |
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Captopril; Cardiovascular System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelin-1; Hyperglycemia; Kidney; Losartan; Male; NADPH Oxidases; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury | 2012 |
Repression of cardiac hypertrophy by KLF15: underlying mechanisms and therapeutic implications.
Topics: Angiotensin II; Animals; Binding Sites; Cardiomegaly; Cell Differentiation; COS Cells; Disease Models, Animal; DNA-Binding Proteins; Gene Expression Regulation; Genetic Therapy; Humans; Kruppel-Like Transcription Factors; Mice; Mutant Proteins; Nuclear Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Trans-Activators; Transcription Factors | 2012 |
Angiotensin II increases corpus cavernosal contractility and oxidative stress in partial bladder outlet obstructed rabbits: relevance to erectile dysfunction.
Topics: Angiotensin II; Animals; Disease Models, Animal; Electric Stimulation; Erectile Dysfunction; Imidazoles; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxidative Stress; Penis; Phosphodiesterase 5 Inhibitors; Piperazines; Rabbits; Sulfones; Triazines; Urinary Bladder Neck Obstruction; Vardenafil Dihydrochloride | 2013 |
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Biomarkers; Blood Pressure; Cytochrome P-450 CYP11B2; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Diseases; Inflammation; Kidney Diseases; Kidney Glomerulus; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Myocardium; Receptors, Mineralocorticoid; Renin-Angiotensin System; Sodium Chloride, Dietary; Spironolactone; Time Factors; Vascular Diseases | 2012 |
Chronic infusion of angiotensin-(1-7) into the lateral ventricle of the brain attenuates hypertension in DOCA-salt rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Collagen Type I; Collagen Type III; Desoxycorticosterone; Disease Models, Animal; Heart Rate; Heart Ventricles; Hypertension; Infusions, Intraventricular; Kidney; Lateral Ventricles; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathetic Nervous System; Time Factors | 2012 |
[Hypertension-induced fibrosis: a balance story].
Topics: Aldosterone; Angiotensin II; Animals; Bone Morphogenetic Proteins; Cardiomegaly; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Failure; Hypertension; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Natriuretic Peptide, Brain; Renin; Renin-Angiotensin System | 2012 |
Role of specific T-type calcium channel blocker R(-) efonidipine in the regulation of renal medullary circulation.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Calcium Channel Blockers; Calcium Channels, T-Type; Dihydropyridines; Disease Models, Animal; Drug Antagonism; Infusions, Intravenous; Ischemia; Kidney Medulla; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitrogen Dioxide; Nitrogen Oxides; Nitrophenols; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstrictor Agents | 2012 |
Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model.
Topics: Angiotensin II; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apoptosis; Azo Compounds; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Endothelial Cells; Fenofibrate; Inflammation; Kidney; Lipoproteins, HDL; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; Sphingosine; Treatment Outcome; Up-Regulation | 2012 |
Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity.
Topics: Acetylcholine; Angiotensin II; Animals; Body Weight; Diet, High-Fat; Disease Models, Animal; Eating; Endothelium, Vascular; Male; Middle Cerebral Artery; Obesity; Rats; Rats, Inbred Dahl; Renin; Renin-Angiotensin System; Vasodilation; Vasodilator Agents | 2012 |
Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model.
Topics: Angiotensin II; Animals; Arterioles; Blood Pressure; Cell Line; Cyclic GMP; Cysteine; Disease Models, Animal; Enzyme Activation; Guanylate Cyclase; Hypertension; Male; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Nitrosation; Oxidative Stress; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Time Factors; Transfection; Vascular Resistance; Vasodilation | 2012 |
Role of copper transport protein antioxidant 1 in angiotensin II-induced hypertension: a key regulator of extracellular superoxide dismutase.
Topics: Adenosine Triphosphatases; Angiotensin II; Animals; Aorta; Blood Pressure; Cation Transport Proteins; Copper; Copper Transport Proteins; Copper-Transporting ATPases; Disease Models, Animal; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Chaperones; Muscle, Smooth, Vascular; Oxygen; Superoxide Dismutase | 2012 |
Parallel changes in neuronal AT1R and GRK5 expression following exercise training in heart failure.
Topics: Angiotensin II; Animals; Cells, Cultured; Chronic Disease; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 5; Heart Failure; Male; Medulla Oblongata; Neurons; NF-kappa B; Paraventricular Hypothalamic Nucleus; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Up-Regulation | 2012 |
Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Echocardiography; Endothelin-1; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Cardiac; Rats; Rats, Wistar | 2012 |
Murine recombinant angiotensin-converting enzyme 2: effect on angiotensin II-dependent hypertension and distinctive angiotensin-converting enzyme 2 inhibitor characteristics on rodent and human angiotensin-converting enzyme 2.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Humans; Hydrolysis; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Leucine; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Recombinant Proteins | 2012 |
The effects of phentolamine on fructose-fed rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Fructose; Hypertension; Insulin; Male; Metabolic Syndrome; Norepinephrine; Phentolamine; Rats; Rats, Wistar; Reactive Nitrogen Species; Uric Acid | 2012 |
Angiotensin II contributes to renal fibrosis independently of Notch pathway activation.
Topics: Angiotensin II; Animals; Calcium-Binding Proteins; Cell Line; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Hydronephrosis; Hypertension; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Kidney; Kidney Tubules; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Podocytes; Rats; Receptor, Angiotensin, Type 1; Receptors, Notch; Serrate-Jagged Proteins; Signal Transduction; Transforming Growth Factor beta1 | 2012 |
Sexual dimorphism in urinary angiotensinogen excretion during chronic angiotensin II-salt hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension; Kidney; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sex Factors; Sodium Chloride, Dietary | 2012 |
Rosuvastatin prevents angiotensin II-induced vascular changes by inhibition of NAD(P)H oxidase and COX-1.
Topics: Angiotensin II; Animals; Atherosclerosis; Cyclooxygenase 1; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Extracellular Matrix; Fibrosis; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mechanical Phenomena; Membrane Proteins; Mesenteric Arteries; NADPH Oxidase 4; NADPH Oxidases; Phosphorylation; Protein Processing, Post-Translational; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Sulfonamides; Vascular Resistance; Vasodilation | 2013 |
Influence of arterial hypertension on colonic healing in rats.
Topics: Anastomosis, Surgical; Angiotensin II; Animals; Blood Pressure; Collagen; Colon; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hypertension; Male; Postoperative Period; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Surgical Wound Dehiscence; Time Factors; Wound Healing | 2012 |
Inhibition of neointimal hyperplasia in the rat carotid artery injury model by a HMGB1 inhibitor.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Cardiovascular Agents; Carotid Arteries; Carotid Artery Injuries; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Glycyrrhizic Acid; HMGB1 Protein; Hyperplasia; Inflammation Mediators; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenotype; Rats; Rats, Sprague-Dawley; Receptors, Notch; Signal Transduction; Time Factors | 2012 |
Effect of renal sympathetic denervation on the inducibility of atrial fibrillation during rapid atrial pacing.
Topics: Aldosterone; Analysis of Variance; Angiography; Angiotensin II; Animals; Atrial Fibrillation; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Heart Atria; Heart Conduction System; Kidney; Renin; Renin-Angiotensin System; Sympathectomy | 2012 |
Chemokine (C-C motif) receptor 2 mediates mast cell migration to abdominal aortic aneurysm lesions in mice.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cell Proliferation; Cells, Cultured; Chemotaxis; Disease Models, Animal; Elastin; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Proto-Oncogene Proteins c-kit; Receptors, CCR2 | 2012 |
Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cathepsin K; Cathepsins; CD3 Complex; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; T-Lymphocytes; Time Factors | 2012 |
Neurohormonal modulation of the innate immune system is proinflammatory in the prehypertensive spontaneously hypertensive rat, a genetic model of essential hypertension.
Topics: Angiotensin II; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Hypertension; Immunity, Innate; Inflammation; Macrophages; Male; Neurotransmitter Agents; Nicotine; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spleen | 2012 |
The role of lysyl oxidase family members in the stabilization of abdominal aortic aneurysms.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Diet, High-Fat; Disease Models, Animal; Extracellular Matrix; Extracellular Matrix Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Protein-Lysine 6-Oxidase; RNA, Messenger; Vasoconstrictor Agents | 2012 |
Endogenous renovascular hypertension combined with low shear stress induces plaque rupture in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Apolipoproteins E; Blood Pressure; Carotid Artery Diseases; Carotid Artery, Common; Collagen; Collagenases; Disease Models, Animal; Female; Hemorrhage; Hypertension, Renovascular; Incidence; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; Stress, Mechanical | 2012 |
Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Fibrosis; Humans; Male; Mice; Mice, Inbred C57BL; Skin Diseases | 2012 |
Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Dual Specificity Phosphatase 1; Gene Expression Regulation; Hypertension; Ion Channels; JNK Mitogen-Activated Protein Kinases; Male; Medulla Oblongata; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Oligonucleotides, Antisense; Oxidative Stress; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Signal Transduction; Uncoupling Protein 2 | 2012 |
Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterial Pressure; Biomarkers; Blood Vessels; Case-Control Studies; Cell Adhesion Molecules; Cell Line; Disease Models, Animal; Humans; Hydralazine; Hypertension; Hypertension, Renovascular; Losartan; Male; Morpholinos; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cell Surface; RNA, Messenger; Time Factors; Up-Regulation; Vasodilator Agents | 2012 |
Remodeling of intrinsic cardiac neurons: effects of β-adrenergic receptor blockade in guinea pig models of chronic heart disease.
Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Cholinergic Agents; Chronic Disease; Disease Models, Animal; Evoked Potentials; Guinea Pigs; Heart; Heart Diseases; Male; Myocardial Infarction; Neurons; Receptors, Adrenergic, beta; Timolol | 2012 |
Early molecular responses of bone to obstructive nephropathy induced by unilateral ureteral obstruction in mice.
Topics: Angiotensin II; Animals; Blotting, Western; Bone Remodeling; Calcium; Chondrocytes; Chronic Kidney Disease-Mineral and Bone Disorder; Disease Models, Animal; Gene Expression Regulation; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tibia; Time Factors; Ureteral Obstruction | 2012 |
Effectiveness of cyclooxygenase-2 inhibition in limiting abdominal aortic aneurysm progression in mice correlates with a differentiated smooth muscle cell phenotype.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Biomarkers; Celecoxib; Cell Differentiation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Pyrazoles; RNA, Messenger; Severity of Illness Index; Sulfonamides; Time Factors | 2012 |
Expression of endothelial lipase correlates with the size of neointima in a murine model of vascular remodeling.
Topics: Angiotensin II; Animals; Carotid Artery, Common; Cell Adhesion; Cell Movement; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Lipase; Lipoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Neointima; Oxidative Stress | 2012 |
Preconditioning protects the heart in a prolonged uremic condition.
Topics: Angiotensin II; Animals; Biomarkers; Creatinine; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Stroke Volume; Time Factors; Tyrosine; Ultrasonography; Urea; Uremia; Uric Acid; Ventricular Function, Left | 2012 |
EP1 disruption attenuates end-organ damage in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Female; Humans; Hydralazine; Hypertension; Kaplan-Meier Estimate; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Receptors, Prostaglandin E, EP1 Subtype | 2012 |
Importance of endothelial NF-κB signalling in vascular remodelling and aortic aneurysm formation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Disease Models, Animal; Endothelium, Vascular; Femoral Artery; Humans; Hyperplasia; I-kappa B Proteins; Inflammation Mediators; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Signal Transduction; Vascular System Injuries | 2013 |
Elevation of plasma high-density lipoproteins inhibits development of experimental abdominal aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Autophagy; Calcium Chloride; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Hypercholesterolemia; Injections, Subcutaneous; JNK Mitogen-Activated Protein Kinases; Lipoproteins, HDL; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Time Factors; Up-Regulation | 2012 |
Treatment with activated protein C (aPC) is protective during the development of myocardial fibrosis: an angiotensin II infusion model in mice.
Topics: Angiotensin II; Animals; Base Sequence; Cytokines; Disease Models, Animal; DNA Primers; Fibrosis; Fluorescent Antibody Technique; Heart Diseases; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Protein C; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice.
Topics: Administration, Oral; Angiotensin II; Animals; Anti-Bacterial Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Blood Pressure; Cholesterol; Diet, High-Fat; Disease Models, Animal; Doxycycline; Infusion Pumps, Implantable; Male; Mice; Mice, Knockout; Receptors, LDL; Vasoconstrictor Agents | 2012 |
Cellular repressor E1A-stimulated genes controls phenotypic switching of adventitial fibroblasts by blocking p38MAPK activation.
Topics: Actins; Adventitia; Angiotensin II; Animals; Biomarkers; Carotid Arteries; Carotid Artery Injuries; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Separation; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Fibroblasts; Flow Cytometry; Fluorescent Antibody Technique; Genotype; Humans; Mice; Microscopy, Fluorescence; p38 Mitogen-Activated Protein Kinases; Phenotype; Protein Kinase Inhibitors; Repressor Proteins; Time Factors; Transfection | 2012 |
Absence of Rgs5 prolongs cardiac repolarization and predisposes to ventricular tachyarrhythmia in mice.
Topics: Action Potentials; Angiotensin II; Animals; Disease Models, Animal; Electrocardiography; Genetic Predisposition to Disease; Heart; In Vitro Techniques; Male; Mice; Mice, Knockout; Myocardium; Potassium; Potassium Channels; Receptor, Angiotensin, Type 1; RGS Proteins; Tachycardia, Ventricular | 2012 |
Oxidative stress exaggerates skeletal muscle contraction-evoked reflex sympathoexcitation in rats with hypertension induced by angiotensin II.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Afferent Pathways; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Pressure; Blotting, Western; Cardiovascular System; Cyclic N-Oxides; Decerebrate State; Disease Models, Animal; Electric Stimulation; Heart Rate; Hindlimb; Hypertension; Injections, Intra-Articular; Kidney; Losartan; Male; Membrane Glycoproteins; Muscle Contraction; Muscle, Skeletal; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reflex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spin Labels; Superoxides; Sympathetic Nervous System; Time Factors | 2013 |
Inhibition of Notch1 signaling reduces abdominal aortic aneurysm in mice by attenuating macrophage-mediated inflammation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteritis; Dipeptides; Disease Models, Animal; Haploinsufficiency; Humans; Macrophages; Male; Mice; Mice, Knockout; Receptor, Notch1; Signal Transduction | 2012 |
Chronic perfusion of angiotensin II causes cognitive dysfunctions and anxiety in mice.
Topics: Angiotensin II; Animals; Anxiety; Blood Pressure; Cognition Disorders; Disease Models, Animal; Drug Delivery Systems; Exploratory Behavior; Male; Maze Learning; Mice; Mice, Inbred C57BL; Time Factors; Vasoconstrictor Agents | 2013 |
Angiotensin II impairs glucose utilization in obese Zucker rats by increasing HPA activity via an adrenal-dependent mechanism.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Angiotensin II; Animals; Blood Glucose; Corticosterone; Disease Models, Animal; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Hypothalamo-Hypophyseal System; Insulin; Insulin Secretion; Male; Metabolic Syndrome; Obesity; Pituitary-Adrenal System; Random Allocation; Rats; Rats, Zucker; Up-Regulation | 2013 |
Arterial and venous endothelia display differential functional fractalkine (CX3CL1) expression by angiotensin-II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Arteries; Arterioles; Atherosclerosis; Cell Adhesion; Cells, Cultured; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Disease Models, Animal; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Female; Human Umbilical Vein Endothelial Cells; Humans; Interferon-gamma; Leukocyte Rolling; Leukocytes; Losartan; Male; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidase 5; NADPH Oxidases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Receptors, Chemokine; RNA Interference; Signal Transduction; Time Factors; Transfection; Tumor Necrosis Factor-alpha; Veins; Venules | 2013 |
Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection.
Topics: Acute Disease; Aged; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Disease Models, Animal; Female; Humans; Male; Matrix Metalloproteinase 9; Mice; Middle Aged; Neutrophil Infiltration; Neutrophils | 2012 |
Proteasome inhibition attenuates heart failure during the late stages of pressure overload through alterations in collagen expression.
Topics: Angiotensin II; Animals; Cells, Cultured; Collagen; Disease Models, Animal; Down-Regulation; Fibrosis; Heart Failure; Heart Ventricles; Hypertension; Leupeptins; Male; Proteasome Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Severity of Illness Index; Signal Transduction; Transforming Growth Factor beta1; Ubiquitin; Ventricular Dysfunction, Left | 2013 |
Aged rats are susceptible to nephrotoxicity induced by iodinated contrast media.
Topics: Aging; Angiotensin II; Animals; Contrast Media; Diatrizoate Meglumine; Disease Models, Animal; Kidney; Kidney Diseases; Male; Malondialdehyde; NADP; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Superoxide Dismutase | 2013 |
Impact of ACE2 deficiency and oxidative stress on cerebrovascular function with aging.
Topics: Acetylcholine; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Male; Mice; Mice, Knockout; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger; Vasculitis; Vasodilation; Vasodilator Agents | 2012 |
Effects of endothelin receptor antagonists on renal hemodynamics in angiotensin II-infused rats on high NaCl intake.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelin Receptor Antagonists; Hemodynamics; Hypertension; Kidney; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sodium Chloride, Dietary | 2012 |
Early life stress induces renal dysfunction in adult male rats but not female rats.
Topics: Age Factors; Aging; Angiotensin II; Animals; Anxiety, Separation; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Creatinine; Disease Models, Animal; Estradiol; Female; Hypertension; Kidney; Kidney Diseases; Male; Maternal Deprivation; Orchiectomy; Proteinuria; Rats; Rats, Inbred WKY; Sex Factors; Stress, Psychological; Telemetry; Testosterone | 2013 |
Antidepressant-like effects of oxytocin in mice are dependent on the presence of insulin-regulated aminopeptidase.
Topics: Age Factors; Aminopeptidases; Angiotensin II; Animals; Antidepressive Agents; Cell Membrane; Cerebral Cortex; Cystinyl Aminopeptidase; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Imipramine; Immobility Response, Tonic; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Oxytocin | 2013 |
Olmesartan attenuates cardiac remodeling through DLL4/Notch1 pathway activation in pressure overload mice.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcium-Binding Proteins; Dipeptides; Disease Models, Animal; Fibrosis; Hypertrophy, Left Ventricular; Imidazoles; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microcirculation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, Notch1; Tetrazoles; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Remodeling | 2013 |
Locally applied leptin induces regional aortic wall degeneration preceding aneurysm formation in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Delayed-Action Preparations; Dilatation, Pathologic; Disease Models, Animal; Humans; Leptin; Macrophages; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Leptin; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Ultrasonography | 2013 |
[Effect of TGRJ on blood press, NO and Ang II in renal hypertensive rats].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Cells, Cultured; Disease Models, Animal; Drugs, Chinese Herbal; Female; Glycosides; Hypertension, Renal; Kidney; Male; Myocytes, Smooth Muscle; Nitric Oxide; Ranunculus; Rats; Rats, Sprague-Dawley | 2012 |
Protective role of vascular smooth muscle cell PPARγ in angiotensin II-induced vascular disease.
Topics: Angiotensin II; Animals; Chemokine CCL2; Disease Models, Animal; Endothelium, Vascular; Hypertension; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; NADP; Oxidative Stress; PPAR gamma; Superoxide Dismutase; Vascular Diseases | 2013 |
Atrial natriuretic peptide exerts protective action against angiotensin II-induced cardiac remodeling by attenuating inflammation via endothelin-1/endothelin receptor A cascade.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Endothelin-1; Fibrillar Collagens; Fibroblasts; Fibrosis; Heart Diseases; Inflammation; Inflammation Mediators; Infusions, Intravenous; Macrophages; Male; Mitral Valve; Myocardial Contraction; Myocardium; Rats; Rats, Inbred WKY; Receptor, Endothelin A; Signal Transduction; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2013 |
Mild hypercholesterolemia blunts the proinflammatory and prothrombotic effects of hypertension on the cerebral microcirculation.
Topics: Angiotensin II; Animals; Apolipoprotein A-I; Blood-Brain Barrier; Cerebrovascular Circulation; Disease Models, Animal; Humans; Hypercholesterolemia; Hypertension; Lipoproteins, HDL; Male; Mice; Mice, Transgenic; Microcirculation; Vasoconstrictor Agents; Venules | 2013 |
Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cells, Cultured; Chemokine CCL5; Chemotaxis, Leukocyte; Disease Models, Animal; Disease Progression; Injections, Intravenous; Leukocytes; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Oligopeptides; Pancreatic Elastase; Platelet Factor 4; Receptors, CCR5; Time Factors | 2013 |
Aberrant endoplasmic reticulum stress in vascular smooth muscle increases vascular contractility and blood pressure in mice deficient of AMP-activated protein kinase-α2 in vivo.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Enzyme Activation; Enzyme Activators; Humans; Hypertension; Leupeptins; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myosin Light Chains; Nitric Oxide Synthase Type III; Phenylbutyrates; Phenylephrine; Phosphorylation; Ribonucleotides; Taurochenodeoxycholic Acid; Time Factors; Tunicamycin; Vasoconstriction; Vasoconstrictor Agents | 2013 |
Angiotensin-(1-7) inhibits vascular calcification in rats.
Topics: Actins; Alkaline Phosphatase; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Calcium-Binding Proteins; Calponins; Cholecalciferol; Cytoskeletal Proteins; Disease Models, Animal; Gene Expression Regulation; Male; Microfilament Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Nicotine; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Vascular Calcification | 2013 |
[Effects of liver hydrolysate on the blood glucose in metabolic syndrome model rats (SHR/NDmcr-cp)].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Blood Glucose; Depression, Chemical; Disease Models, Animal; Glucose Tolerance Test; Glycated Hemoglobin; Insulin Resistance; Liver; Male; Metabolic Syndrome; Oxidative Stress; Protein Hydrolysates; Rats; Rats, Inbred SHR | 2013 |
Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Communication; Disease Models, Animal; Disease Progression; DNA Primers; Dose-Response Relationship, Drug; Fatty Liver; Gene Expression; Hepatic Stellate Cells; Liver Cirrhosis; Losartan; Male; NF-kappa B; Non-alcoholic Fatty Liver Disease; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Toll-Like Receptor 4; Transforming Growth Factor beta | 2013 |
[Adenosine receptors agonists mitigated PAH of rats induced by chronic hypoxia through reduction of renin activity/angiotensin II levels and increase of inducible nitric oxide synthase-nitric oxide levels].
Topics: Adenosine; Angiotensin II; Animals; Disease Models, Animal; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Proliferating Cell Nuclear Antigen; Pulmonary Artery; Purinergic P1 Receptor Agonists; Random Allocation; Rats; Rats, Sprague-Dawley; Renin | 2012 |
Chronic angiotensin-II treatment potentiates HR slowing in Sprague-Dawley rat during acute behavioral stress.
Topics: Angiotensin II; Animals; Avoidance Learning; Behavior, Animal; Blood Pressure; Bradycardia; Cardiovascular System; Disease Models, Animal; Drug Implants; Heart Rate; Hypertension; Male; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Stress, Psychological | 2013 |
Overexpression of SOCS3 in T lymphocytes leads to impaired interleukin-17 production and severe aortic aneurysm formation in mice--brief report.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aortic Aneurysm, Abdominal; Aortic Rupture; Bone Marrow Transplantation; Cells, Cultured; Disease Models, Animal; Genotype; Interleukin-17; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neutrophils; Phenotype; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Th17 Cells; Time Factors; Transforming Growth Factor beta; Up-Regulation; Whole-Body Irradiation | 2013 |
Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Movement; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Everolimus; Flow Cytometry; Infusion Pumps, Implantable; Infusions, Subcutaneous; Interferon-gamma; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Protein Kinase Inhibitors; Receptor, Macrophage Colony-Stimulating Factor; Receptors, CCR2; Sirolimus; TOR Serine-Threonine Kinases | 2013 |
ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Echocardiography; Energy Metabolism; Fatty Acids; Glucose; Glucose Tolerance Test; Heart; Heart Failure, Diastolic; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Oxidation-Reduction; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Renin-Angiotensin System; Sirtuin 3 | 2013 |
Salusin-β in paraventricular nucleus increases blood pressure and sympathetic outflow via vasopressin in hypertensive rats.
Topics: Angiotensin II; Animals; Antibodies; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Arterial Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hormone Antagonists; Hypertension, Renovascular; Intercellular Signaling Peptides and Proteins; Kidney; Male; Medulla Oblongata; Microinjections; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Sympathetic Nervous System; Time Factors | 2013 |
Angiotensin II regulation of vascular endothelial growth factor and receptors Flt-1 and KDR/Flk-1 in cyclosporine nephrotoxicity.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cyclosporine; Disease Models, Animal; Enalapril; Endothelial Growth Factors; Extracellular Matrix Proteins; Gene Expression; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Kidney Diseases; Losartan; Lymphokines; Male; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors | 2002 |
Growth characteristics, angiotensin II generation, and microarray-determined gene expression in vascular smooth muscle cells from young spontaneously hypertensive rats.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Gene Expression Profiling; Genetic Markers; Genetic Predisposition to Disease; Intercellular Signaling Peptides and Proteins; Male; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Phenotype; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Systole; Transcription, Genetic | 2002 |
Tempol selectively attenuates angiotensin II evoked vasoconstrictor responses in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Luminescent Measurements; Male; Mesenteric Arteries; Models, Cardiovascular; NG-Nitroarginine Methyl Ester; Perfusion; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Spin Labels; Superoxides; Vasoconstriction | 2002 |
Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor.
Topics: Adrenomedullin; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzazepines; Biomarkers; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Heart; Hypertension; Male; Models, Cardiovascular; Neprilysin; Organ Size; Peptides; Pyridines; Ramipril; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, Bradykinin; Severity of Illness Index; Systole; Treatment Outcome; Vasoconstrictor Agents | 2002 |
Upregulation of autocrine-paracrine renin-angiotensin systems in chronic renovascular hypertension.
Topics: Adrenal Glands; Angiotensin II; Animals; Autocrine Communication; Chronic Disease; Disease Models, Animal; Hypertension, Renovascular; Immunohistochemistry; Kidney; Kidney Tubules, Proximal; Radioimmunoassay; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Up-Regulation | 2002 |
L-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure.
Topics: Angiotensin II; Animals; Apoptosis; Carnitine; Caspase 3; Caspase 9; Caspases; Cell Nucleus; Cells, Cultured; Cytoprotection; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Glucose Transporter Type 4; Heart Failure; In Situ Nick-End Labeling; Liver Function Tests; Male; Monocrotaline; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Muscular Disorders, Atrophic; Myosin Heavy Chains; Protein Isoforms; Rats; Rats, Sprague-Dawley; Sphingolipids; Staurosporine; Tumor Necrosis Factor-alpha | 2002 |
Vasoactive peptides in a pulmonary embolism model.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Disease Models, Animal; Dogs; Pulmonary Embolism; Vasoconstriction | 2002 |
Distinct role of intrarenal cyclooxygenase-1/2 in chronic unilateral renal ischemia.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Dogs; Glomerular Filtration Rate; Ischemia; Isoenzymes; Kidney; Kidney Failure, Chronic; Male; Prostaglandin-Endoperoxide Synthases; Renal Circulation; Sodium | 2002 |
Lengthy suppression of vascular proliferation by a chymase inhibitor in dog grafted veins.
Topics: Angiotensin II; Animals; Chymases; Coronary Artery Bypass; Disease Models, Animal; Dogs; Femoral Vein; Hyperplasia; Japan; Models, Cardiovascular; Oligopeptides; Peptidyl-Dipeptidase A; Serine Endopeptidases; Treatment Outcome; Tunica Intima | 2002 |
Role of ANG II in coronary capillary angiogenesis at the insulin-resistant stage of a NIDDM rat model.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Capillaries; Coronary Circulation; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Growth Factors; Extracellular Matrix Proteins; Gene Expression; Glycation End Products, Advanced; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin Resistance; Lymphokines; Male; Neovascularization, Physiologic; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Receptor Protein-Tyrosine Kinases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Tetrazoles; Transcription Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Iron overload augments angiotensin II-induced cardiac fibrosis and promotes neointima formation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Blotting, Western; Disease Models, Animal; Drug Synergism; Fibrosis; Heart; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hypertension; Immunohistochemistry; Iron Chelating Agents; Iron Overload; Iron-Dextran Complex; Losartan; Male; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tunica Intima; Vasodilator Agents | 2002 |
[Regulation of cyclin-dependent kinase inhibitors by mitogen-activated protein kinase in angiotensin II-stimulated vascular smooth muscle cell hypertrophy].
Topics: Angiotensin II; Animals; Cardiomyopathy, Hypertrophic; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Disease Models, Animal; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Tumor Suppressor Proteins | 2002 |
Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cells, Cultured; Chemokines; Cytokines; Disease Models, Animal; Female; Immune Complex Diseases; Inflammation Mediators; Infusion Pumps; Infusions, Parenteral; Kidney; Mesangial Cells; Nephritis; Quinapril; Rats; Rats, Wistar; RNA, Messenger; Tetrahydroisoquinolines; Tumor Necrosis Factor-alpha; Up-Regulation | 2002 |
Angiotensin blockade prevents type 2 diabetes by formation of fat cells.
Topics: Adipocytes; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Cell Differentiation; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Telmisartan | 2002 |
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis | 2002 |
Release of preformed Ang II from myocytes mediates angiotensinogen and ET-1 gene overexpression in vivo via AT1 receptor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Aortic Valve Stenosis; Cardiac Catheterization; Cytoplasm; Disease Models, Animal; Endothelin-1; Gene Expression Regulation; Heart; Insulin-Like Growth Factor I; Microscopy, Confocal; Myocardium; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Stress, Mechanical; Swine; Systole; Tetrazoles; Valine; Valsartan | 2002 |
Time-dependent expression of chymase and angiotensin converting enzyme in the hamster heart under pressure overload.
Topics: Angiotensin II; Animals; Cardiomegaly; Chymases; Cricetinae; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypertension, Renal; Male; Myocardium; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Serine Endopeptidases; Time Factors; Transcription, Genetic; Ventricular Pressure | 2002 |
Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation.
Topics: Angiotensin II; Animals; Basic Helix-Loop-Helix Transcription Factors; Calcium-Binding Proteins; Carotid Arteries; Carotid Artery Diseases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; DNA-Binding Proteins; Down-Regulation; Drosophila Proteins; Glycosylation; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Insect Proteins; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Male; Membrane Proteins; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nuclear Proteins; Platelet-Derived Growth Factor; Proteins; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Receptor, Notch2; Receptors, Cell Surface; RNA, Messenger; Serrate-Jagged Proteins; Signal Transduction; Transcription Factors; Tumor Suppressor Proteins | 2002 |
Expression and regulation of ST2, an interleukin-1 receptor family member, in cardiomyocytes and myocardial infarction.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Biomarkers; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Humans; Imidazoles; Interleukin-1; Interleukin-1 Receptor-Like 1 Protein; Interleukin-4; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Nuclease Protection Assays; Phorbol Esters; Promoter Regions, Genetic; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Receptors, Interleukin; Receptors, Interleukin-1; RNA, Messenger; Stress, Mechanical; Stroke Volume | 2002 |
The predominant role of brain angiotensinogen and angiotensin in environmentally induced hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Cold Temperature; Disease Models, Animal; Hypertension; Hypothalamus; Liver; Male; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Time Factors | 2002 |
Angiotensin II and oxidative stress in Dahl Salt-sensitive rat with heart failure.
Topics: Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Disease Models, Animal; Gene Expression; Heart Failure; Heart Ventricles; Hydrogen Peroxide; Imidazoles; Imidazolidines; Kidney; Male; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Rats; Rats, Inbred Dahl; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Aorta; Aspartic Acid Endopeptidases; Disease Models, Animal; Echocardiography; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Extracellular Matrix; Fibroblast Growth Factor 2; Fibronectins; Heart Diseases; Heart Ventricles; Humans; Immunohistochemistry; Kidney; Male; Metalloendopeptidases; Prodrugs; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 2002 |
Increase in Cx45 gap junction channels in cerebral smooth muscle cells from SHR.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Brain; Cell Line; Cerebral Arteries; Connexin 43; Connexins; Disease Models, Animal; Enzyme Inhibitors; Female; Femoral Artery; Gap Junctions; Humans; Hypertension; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Patch-Clamp Techniques; Quinine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2002 |
Inhaled nitric oxide modifies left ventricular diastolic stress in the presence of vasoactive agents in heart failure.
Topics: Acetylcholine; Administration, Inhalation; Angiotensin II; Animals; Diastole; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Heart Failure; Hemodynamics; Infusions, Intravenous; Isoproterenol; Male; Nitric Oxide; Nitroglycerin; Norepinephrine; Procainamide; Pulmonary Circulation; Random Allocation; Stroke Volume; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents; Ventricular Function, Left | 2003 |
Angiotensin II: a vasoactive hormone with ever-increasing biological roles.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Hormones; Humans; Muscle, Smooth, Vascular; Oligonucleotide Array Sequence Analysis; Proteome; Rats; Reproducibility of Results | 2003 |
Cardiorenal and humoral properties of a novel direct soluble guanylate cyclase stimulator BAY 41-2272 in experimental congestive heart failure.
Topics: Aldosterone; Angiotensin II; Animals; Cardiac Output; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Glomerular Filtration Rate; Guanylate Cyclase; Heart; Heart Failure; Heart Function Tests; Hemodynamics; Injections, Intravenous; Kidney; Kidney Function Tests; Male; Nitroglycerin; Pyrazoles; Pyridines; Receptors, Cytoplasmic and Nuclear; Renin; Renin-Angiotensin System; Soluble Guanylyl Cyclase | 2003 |
Sympatho-inhibitory actions of irbesartan in pithed spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Decerebrate State; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hypertension; Irbesartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Species Specificity; Sympathetic Nervous System; Sympatholytics; Tetrazoles | 2003 |
Cardiac fibrosis occurs early and involves endothelin and AT-1 receptors in hypertension due to endogenous angiotensin II.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Bosentan; Cardiomyopathies; Dansyl Compounds; Disease Models, Animal; Endothelin-1; Fibrosis; Hypertension; Irbesartan; Male; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Sulfonamides; Tetrazoles; Time Factors; Vasoconstrictor Agents | 2003 |
Angiotensins in plasma of hypertensive rats and human.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Disease Models, Animal; Enalapril; Humans; Hypertension; Male; Middle Aged; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar | 2003 |
The effects of sarmesin, an Angiotensin II analogue on seizure susceptibility, memory retention and nociception.
Topics: Angiotensin II; Animals; Avoidance Learning; Disease Models, Animal; Drug Combinations; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Losartan; Male; Memory; Mice; Pain Measurement; Pentylenetetrazole; Pyridines; Seizures; Tail | 2003 |
Hypoxia, angiotensin-II, and norepinephrine mediated apoptosis is stimulus specific in canine failed cardiomyocytes: a role for p38 MAPK, Fas-L and cyclin D1.
Topics: Angiotensin II; Animals; Apoptosis; Cyclin D1; Disease Models, Animal; Dogs; Fas Ligand Protein; Follow-Up Studies; Heart Failure; Hypoxia; Incidence; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Models, Cardiovascular; Myocytes, Cardiac; Norepinephrine; p38 Mitogen-Activated Protein Kinases | 2003 |
Cardiac interstitial bradykinin and mast cells modulate pattern of LV remodeling in volume overload in rats.
Topics: Acute Disease; Angiotensin II; Animals; Aorta; Arteriovenous Fistula; Bradykinin; Cardiac Volume; Cell Count; Chymases; Consciousness; Disease Models, Animal; Extracellular Space; Mast Cells; Microdialysis; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Vena Cava, Inferior; Ventricular Remodeling | 2003 |
[Dexamethasone regulate the neuropeptide expression in rabbit's brain injury induced by endotoxin].
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Atrial Natriuretic Factor; Brain Edema; Brain Injuries; Calcitonin Gene-Related Peptide; Dexamethasone; Disease Models, Animal; Endothelins; Endotoxins; Female; Male; Neuropeptides; Rabbits | 2002 |
Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Captopril; Disease Models, Animal; Endothelium, Vascular; Female; Hemodynamics; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Vasodilation; Ventricular Fibrillation | 2003 |
Expression of the translational repressor NAT1 in experimental models of cardiac hypertrophy.
Topics: Acetyltransferases; Angiotensin II; Animals; Arylamine N-Acetyltransferase; Body Weight; Cardiomegaly; Carrier Proteins; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Hypertension; Isoenzymes; Male; Molecular Weight; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; RNA Processing, Post-Transcriptional | 2003 |
NAD(P)H oxidase activation by angiotensin II is dependent on p42/44 ERK-MAPK pathway activation in rat's vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Hypertension; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Superoxides; Thioctic Acid; Vasoconstrictor Agents | 2003 |
Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure.
Topics: Angiotensin II; Animals; Chymases; Collagen Type I; Collagen Type III; Diastole; Disease Models, Animal; Disease Progression; Dogs; Enzyme Inhibitors; Fibrosis; Heart Failure; Hemodynamics; Mast Cells; Myocardium; Peptidyl-Dipeptidase A; RNA, Messenger; Serine Endopeptidases; Transforming Growth Factor beta; Ventricular Dysfunction, Left | 2003 |
Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Buthionine Sulfoximine; Cyclic AMP; Cyclic GMP; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; F2-Isoprostanes; Glutathione; Heart Rate; Hypertension; Kidney; Losartan; Male; Models, Cardiovascular; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Thromboxane A2; Treatment Outcome | 2003 |
Role for chymase in heart failure: angiotensin II-dependent or -independent mechanisms?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Chymases; Disease Models, Animal; Dogs; Enzyme Inhibitors; Extracellular Space; Heart Failure; Humans; In Vitro Techniques; Mast Cells; Mice; Myocardium; Peptidyl-Dipeptidase A; Serine Endopeptidases; Transforming Growth Factor beta | 2003 |
Beta1-adrenergic receptor blockade attenuates angiotensin II-mediated catecholamine release into the cardiac interstitium in mitral regurgitation.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Catecholamines; Collagen; Disease Models, Animal; Dogs; Drug Administration Routes; Epinephrine; Extracellular Space; Female; Heart; Hemodynamics; Male; Metoprolol; Mitral Valve Insufficiency; Myocardium; Neurons; Norepinephrine; Ventricular Function, Left | 2003 |
Induction of left ventricular remodeling and dysfunction in the recipient heart after donor heart myocardial infarction: new insights into the pathologic role of tumor necrosis factor-alpha from a novel heterotopic transplant-coronary ligation rat model.
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart Transplantation; Immunohistochemistry; Male; Rats; Rats, Inbred Lew; Receptors, Tumor Necrosis Factor; Stroke Volume; Transplantation, Heterotopic; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Remodeling | 2003 |
17 Beta-estradiol attenuates development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Estradiol; Female; Inflammation; Male; Mice | 2003 |
Study of the hypothalamic angiotensin system in aortic coarctated rats using the reverse microdialysis technique.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Coarctation; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Hydroxyindoleacetic Acid; Hypothalamus, Anterior; Hypothalamus, Posterior; Irbesartan; Male; Microdialysis; Perfusion; Rats; Rats, Wistar; Receptors, Angiotensin; Serotonin; Tetrazoles | 2003 |
The role of inducible nitric oxide synthase inhibitor on the arteriolar hyporesponsiveness in hemorrhagic-shocked rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance | 2003 |
Expression of bradykinin receptors in the left ventricles of rats with pressure overload hypertrophy and heart failure.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Echocardiography; Fibrosis; Gene Expression; Heart Failure; Hypertrophy, Left Ventricular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Bradykinin B2; Receptors, Bradykinin; RNA, Messenger; Vasoconstrictor Agents | 2003 |
Angiotensin II inhibition increases cellular glucose transport during reperfusion but not ischemia in pig hearts.
Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiac Pacing, Artificial; Cell Membrane; Disease Models, Animal; Female; Glucose; Glucose Transporter Type 4; Glycogen; Heart Rate; Infusions, Intravenous; Insulin; Male; Models, Cardiovascular; Monosaccharide Transport Proteins; Muscle Proteins; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Renin; Swine; Systole; Time Factors | 2003 |
Anti-monocyte chemoattractant protein-1 gene therapy attenuates left ventricular remodeling and failure after experimental myocardial infarction.
Topics: Angiotensin II; Animals; Chemokine CCL2; Cytokines; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Genetic Therapy; Heart Failure; Humans; Immunohistochemistry; Male; Matrix Metalloproteinases; Mice; Muscle, Skeletal; Myocardial Infarction; Myocardium; Sequence Deletion; Survival Rate; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Remodeling | 2003 |
End-organ susceptibility as a determinant of renal disease in hypertension.
Topics: Aged; Angiotensin II; Animals; Disease Models, Animal; Disease Susceptibility; Female; Humans; Hypertension, Renal; Kidney Diseases; Middle Aged; Nitric Oxide; Rats; Rats, Inbred Dahl; Rats, Inbred SHR | 2003 |
Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Aorta; Bacterial Proteins; Blood Pressure; Cardiomegaly; Constriction, Pathologic; Disease Models, Animal; Disease Progression; Hypertension; Isoenzymes; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Myocardium; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species | 2003 |
Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Body Weight; Cardiomegaly; Coronary Vessels; Disease Models, Animal; Disease Progression; Fibrosis; Gene Expression; Heart Rate; Infusion Pumps, Implantable; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardium; Receptor, Angiotensin, Type 1; Superoxides; Ventricular Remodeling | 2003 |
Ultrastructural changes in the remnant kidney (after 5/6 nephrectomy) glomerulus after losartan and atenolol treatment.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atenolol; Basement Membrane; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Hypertrophy; Kidney Failure, Chronic; Kidney Glomerulus; Losartan; Male; Microscopy, Electron; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Systole; Time Factors | 2003 |
Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury.
Topics: Aldosterone; Angiotensin II; Animals; Cardiovascular Diseases; Coronary Artery Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Myocardium; NG-Nitroarginine Methyl Ester; Plasminogen Activator Inhibitor 1; Proteinuria; Sodium, Dietary; Spironolactone | 2003 |
Reinduction of T-type calcium channels by endothelin-1 in failing hearts in vivo and in adult rat ventricular myocytes in vitro.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Calcium Channels, T-Type; Cells, Cultured; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Heart Ventricles; Male; Myocytes, Cardiac; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sulfonamides | 2003 |
Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomarkers; Captopril; Disease Models, Animal; Echocardiography; Endothelin-1; Genetic Markers; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Receptors, Aryl Hydrocarbon; RNA, Messenger; Ventricular Myosins | 2003 |
Pharmacokinetics and the cardiovascular effects of irbesartan in aortic coarctated rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Aortic Coarctation; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Female; Heart Rate; Hypothalamus, Anterior; Injections, Intraperitoneal; Injections, Intravenous; Irbesartan; Metabolic Clearance Rate; Microdialysis; Protein Binding; Rats; Rats, Wistar; Tetrazoles; Time Factors; Tissue Distribution | 2004 |
Entacapone protects from angiotensin II-induced inflammation and renal injury.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Blood Pressure; Cardiomegaly; Catechol O-Methyltransferase; Catechols; Creatinine; Dinoprost; Disease Models, Animal; Dopamine; Enzyme Inhibitors; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; Leukocytes; Male; Models, Cardiovascular; Nitriles; Norepinephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2003 |
Compared to angiotensin II, epinephrine is associated with high myocardial blood flow following return of spontaneous circulation after cardiac arrest.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Flow Velocity; Cardiopulmonary Resuscitation; Coronary Circulation; Disease Models, Animal; Drug Therapy, Combination; Epinephrine; Female; Heart Arrest; Hemodynamics; Male; Probability; Reference Values; Sensitivity and Specificity; Sus scrofa | 2003 |
Enhanced oxidative stress and impaired thioredoxin expression in spontaneously hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II; Animals; Blotting, Western; Deoxyguanosine; Disease Models, Animal; Gene Expression Regulation; Hypertension; Immunohistochemistry; Monocytes; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thioredoxins | 2004 |
[Renal protective effect of angiotensin II receptor antagonist on growth hormone-treated nephrotic rats].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibiotics, Antineoplastic; Biphenyl Compounds; Blood Urea Nitrogen; Collagen Type IV; Creatinine; Disease Models, Animal; Doxorubicin; Fibronectins; Growth Hormone; Immunohistochemistry; Irbesartan; Kidney Diseases; Kidney Glomerulus; Male; Peptidyl-Dipeptidase A; Proteinuria; Random Allocation; Rats; Rats, Sprague-Dawley; Serum Albumin; Tetrazoles; Transforming Growth Factor beta; Triglycerides | 2003 |
Tissue angiotensin II in the regulation of inflammatory and fibrogenic components of repair in the rat heart.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Collagen Type I; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Heart; In Situ Hybridization; Infusions, Parenteral; Male; Myocardium; Nephrectomy; NF-kappa B; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan | 2004 |
Sub-depressor dose of angiotensin type-1 receptor blocker inhibits transforming growth factor-beta-mediated perivascular fibrosis in hypertensive rat hearts.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Collagen; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; Endomyocardial Fibrosis; Fibroblasts; Hypertension; Male; Myocytes, Cardiac; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Transforming Growth Factor beta; Ventricular Remodeling | 2003 |
How does angiotensin II cause renal injury?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Disease Progression; Humans; Hypertension; Hypertension, Renal; Kidney Diseases; Kidney Glomerulus; Models, Biological; Peptidyl-Dipeptidase A; Rats; Renal Circulation; Renal Insufficiency; Renin-Angiotensin System; Vasoconstriction | 2004 |
Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon.
Topics: Allopurinol; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Capillaries; Captopril; Cell Adhesion; Chemokines; Chemotaxis, Leukocyte; Colon; Constriction; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Gene Expression Regulation; Inflammation; Ischemia; Leukocyte Count; Leukocytes; Losartan; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2004 |
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Cardiomyopathy, Hypertrophic; Coronary Vessels; Disease Models, Animal; Enzyme Induction; Imidazoles; Ligation; Losartan; Male; Myocardial Infarction; Myocardium; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Ventricular Remodeling | 2004 |
gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcholine; Angiotensin II; Animals; Antioxidants; Aorta; Bacterial Toxins; Cardiomyopathy, Hypertrophic; Cytochromes b; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; ErbB Receptors; Glycoproteins; Hypertension, Renovascular; Indoles; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Organ Culture Techniques; Polyethylene Glycols; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; Superoxide Dismutase; Superoxides; Tyrphostins; Vasodilation; Vasodilator Agents | 2004 |
Evidence of the role of angiotensin AT(1) receptors in remote renal preconditioning of myocardium.
Topics: Angiotensin II; Animals; Blood Pressure; Body Temperature; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Ischemia; Ischemic Preconditioning, Myocardial; Kidney; Losartan; Male; Myocardial Infarction; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renal Artery; Reperfusion; Time Factors | 2004 |
Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Brain Chemistry; Captopril; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hindlimb; Histamine; Histamine N-Methyltransferase; Hypotension; Hypothalamus; Imidazoles; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Male; Medulla Oblongata; Naphthyridines; Pyridines; Pyrimethamine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Resuscitation; Shock, Hemorrhagic; Time Factors; Vascular Resistance | 2004 |
Small artery mechanics in hyperhomocysteinemic mice: effects of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Collagen; Disease Models, Animal; Elastin; Female; Homocysteine; Hyperhomocysteinemia; Male; Mesenteric Arteries; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Knockout; Vasoconstrictor Agents | 2004 |
Nitric oxide synthase inhibition accelerates the pressor response to low-dose angiotensin II, exacerbates target organ damage, and induces renin escape.
Topics: Angiotensin II; Animals; Biomarkers; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrosis; Infusions, Intravenous; Kidney; Models, Cardiovascular; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Sprague-Dawley; Renin; Time Factors; Troponin T; Vasoconstrictor Agents | 2004 |
Osteopontin modulates angiotensin II-induced fibrosis in the intact murine heart.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Blotting, Northern; Cardiomegaly; Cell Adhesion; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Matrix; Fibroblasts; Fibrosis; Mice; Mice, Knockout; Models, Cardiovascular; Muscle Proteins; Myocardium; Nuclear Proteins; Osteopontin; Repressor Proteins; Sialoglycoproteins; Up-Regulation; Vasoconstrictor Agents | 2004 |
Thioredoxin-interacting protein controls cardiac hypertrophy through regulation of thioredoxin activity.
Topics: Angiotensin II; Animals; Aortic Diseases; Cardiomegaly; Carrier Proteins; Cell Cycle Proteins; Cell Size; Cells, Cultured; Constriction, Pathologic; Disease Models, Animal; Genetic Vectors; Heart; Ligation; Male; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Phenylephrine; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Single-Blind Method; Stress, Mechanical; Thioredoxins; Transcriptional Activation | 2004 |
Sildenafil alters calcium signaling and vascular tone in pulmonary arteries from chronically hypoxic rats.
Topics: Angiotensin II; Animals; Caffeine; Calcium; Calcium Signaling; Chronic Disease; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Male; Muscle, Smooth, Vascular; Phenylephrine; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Cardiomyopathies; Cell Differentiation; Cell Division; Cells, Cultured; Collagen; Cyclic AMP; Disease Models, Animal; Fibroblasts; Fibrosis; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Muscle, Smooth, Vascular; Myocytes, Cardiac; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Receptors, G-Protein-Coupled; Receptors, Peptide; Relaxin; RNA, Messenger; Transforming Growth Factor beta; Vasoconstrictor Agents | 2004 |
Comparative effects of quinapril with enalapril in rats with heart failure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomyopathy, Dilated; Collagen Type III; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Fibrosis; Male; Myocardium; Quinapril; Rats; Rats, Inbred Lew; RNA, Messenger; Survival Rate; Tetrahydroisoquinolines; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Function, Left; Ventricular Pressure | 2004 |
Angiotensin deficiency in mice leads to dilated cardiomyopathy.
Topics: Angiotensin II; Angiotensinogen; Animals; Cardiomyopathy, Dilated; Disease Models, Animal; Echocardiography; Hemodynamics; Hypotension; Male; Mice; Mice, Knockout; Netherlands; Receptors, Angiotensin; Stroke Volume; Ventricular Function, Left | 2004 |
The upregulation of ICAM-1 and P-selectin requires high blood pressure but not circulating renin-angiotensin system in vivo.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cell Adhesion; Disease Models, Animal; Endothelium, Vascular; Hypertension; Intercellular Adhesion Molecule-1; Macrophages; Male; Monocytes; NF-kappa B; P-Selectin; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Transcription Factor RelA; Up-Regulation | 2004 |
The renin-angiotensin system: a 21st century perspective.
Topics: Angiotensin II; Animals; Diabetes Mellitus; Disease Models, Animal; Humans; NG-Nitroarginine Methyl Ester; Reactive Oxygen Species; Renin; Renin-Angiotensin System | 2004 |
Differential gene expression of adrenomedullin receptors in pressure- and volume-overloaded heart--role of angiotensin II.
Topics: Angiotensin II; Animals; Calcitonin Receptor-Like Protein; Disease Models, Animal; Gene Expression Regulation; Heart; Hemodynamics; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Nuclear Proteins; Pressure; Rats; Rats, Wistar; Receptor Activity-Modifying Protein 2; Receptor Activity-Modifying Protein 3; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Calcitonin; Receptors, Peptide; RNA, Messenger; Ubiquitin-Protein Ligases | 2004 |
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Valve Stenosis; Apoptosis; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Disease Progression; Endoplasmic Reticulum; Gene Expression Regulation; Heart Failure; Humans; Imidazoles; Ligation; Male; Mice; Mice, Inbred C57BL; Molecular Chaperones; Myocytes, Cardiac; Natriuretic Peptide, Brain; Olmesartan Medoxomil; Rats; Rats, Inbred WKY; RNA, Messenger; Signal Transduction; Stress, Physiological; Tetrazoles; Thapsigargin; Tunicamycin | 2004 |
Hypertension: a novel regulator of adaptive immunity in atherosclerosis?
Topics: Adaptation, Physiological; Angiotensin II; Animals; Apolipoproteins E; Arteriosclerosis; Collagen; Disease Models, Animal; Fibrosis; Humans; Hypertension; Hypertension, Renovascular; Inflammation; Ligation; Lipids; Macrophages; Mice; Nephrectomy; Phenotype; Rabbits; Renal Artery; Renin-Angiotensin System; Th1 Cells; Th2 Cells | 2004 |
Extracellular signal regulated kinase and SMAD signaling both mediate the angiotensin II driven progression towards overt heart failure in homozygous TGR(mRen2)27.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Atrial Natriuretic Factor; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Collagen Type I; Disease Models, Animal; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Fibrosis; Heart Failure; Homozygote; Hypertrophy, Left Ventricular; Imidazoles; Immunohistochemistry; Male; Mitogen-Activated Protein Kinases; Myocardium; Protein-Tyrosine Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Smad Proteins; Tetrazoles; Time Factors; Trans-Activators; Tyrphostins | 2004 |
Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death.
Topics: Angiotensin II; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Blood Pressure; Bradykinin; Death, Sudden; Disease Models, Animal; Female; Gene Targeting; Heart Block; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myosin Heavy Chains; Peptidyl-Dipeptidase A; Promoter Regions, Genetic; Recombination, Genetic; Tissue Distribution | 2004 |
Angiotensin II amplifies macrophage-driven atherosclerosis.
Topics: Angiotensin II; Animals; Apolipoproteins E; Arteriosclerosis; Bone Marrow Transplantation; Cell Movement; Cholesterol; Disease Models, Animal; Female; Infusion Pumps, Implantable; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL | 2004 |
Enhanced activity of central adrenergic neurons in two-kidney, one clip hypertension in Sprague-Dawley rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cell Count; Disease Models, Animal; Heart Rate; Hypertension, Renovascular; Immunohistochemistry; Male; Neurons; Nitroprusside; Phenylethanolamine N-Methyltransferase; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Renal Artery Obstruction; Vasoconstrictor Agents | 2004 |
In vivo administration of D-arginine: effects on blood pressure and vascular function in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Arginine; Disease Models, Animal; Hypertension; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vascular Resistance | 2004 |
Angiotensin II type 2 receptor gene transfer elicits cardioprotective effects in an angiotensin II infusion rat model of hypertension.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiomyopathies; Cardiotonic Agents; Disease Models, Animal; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Hypertension; Hypertrophy, Left Ventricular; Infusion Pumps, Implantable; Lentivirus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2 | 2004 |
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclic N-Oxides; Disease Models, Animal; Glucose; Hypertension; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan | 2005 |
Angiotensin II mediates acinar cell apoptosis during the development of rat pancreatic fibrosis by AT1R.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Disease Models, Animal; Fibrosis; Gene Expression Regulation; In Situ Nick-End Labeling; Losartan; Male; Pancreas; Pancreatic Ducts; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid | 2004 |
Contractile response of femoral arteries in pigs with acute liver failure.
Topics: Angiotensin II; Animals; Disease Models, Animal; Female; Femoral Artery; Heart Function Tests; Hemodynamics; Liver Failure, Acute; Muscle, Smooth, Vascular; Norepinephrine; Probability; Random Allocation; Sensitivity and Specificity; Swine; Vasoconstriction; Vasodilation | 2004 |
Salt-sensitive hypertension develops after transient induction of ANG II-dependent hypertension in Cyp1a1-Ren2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; Cytochrome P-450 CYP1A1; Disease Models, Animal; Glomerular Filtration Rate; Hypertension, Renal; Indoles; Mice; Rats; Renal Circulation; Renin; Sodium Chloride, Dietary | 2005 |
[Role of calcium desensitization in vascular hyporeactivity in hemorrhagic shock].
Topics: Angiotensin II; Animals; Calcium; Disease Models, Animal; Female; Insulin; Male; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Norepinephrine; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; Shock, Hemorrhagic; Vasoconstriction | 2005 |
Vascular smooth muscle cell NAD(P)H oxidase activity during the development of hypertension: Effect of angiotensin II and role of insulinlike growth factor-1 receptor transactivation.
Topics: Age Factors; Angiotensin II; Animals; Blood Pressure; Cell Culture Techniques; Disease Models, Animal; Hypertension; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NADPH Oxidases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Receptor, IGF Type 1; Transcriptional Activation; Vasoconstrictor Agents | 2005 |
Hypoxia-inducible factor-1alpha is involved in the attenuation of experimentally induced rat glomerulonephritis.
Topics: Angiotensin II; Animals; Cell Survival; Crotalid Venoms; Disease Models, Animal; Disease Progression; Glomerulonephritis; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Rats; Rats, Wistar; Trimeresurus | 2005 |
Critical role of angiotensin II in excess salt-induced brain oxidative stress of stroke-prone spontaneously hypertensive rats.
Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood-Brain Barrier; Calcium Channel Blockers; Cell Proliferation; Cerebral Arteries; Cerebral Cortex; Disease Models, Animal; Hippocampus; Hypertensive Encephalopathy; Male; Neurons; Oxidative Stress; Rats; Rats, Inbred SHR; Sodium Chloride; Stroke; Superoxides; Tetrazoles | 2005 |
EGF receptor transactivation in angiotensin II and endothelin control of vascular protein synthesis in vivo.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelins; ErbB Receptors; Heart Rate; Hypertension; Infusion Pumps, Implantable; Mesenteric Arteries; Protein Biosynthesis; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tyrphostins | 2004 |
Effects of endothelin receptor antagonist on expression of AT1 and AT2 receptors in the heart of SHR-SP.
Topics: Angiotensin II; Animals; Coronary Vessels; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Hypertension; Indans; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Stroke | 2004 |
Enhanced expression of fibrillin-1, a constituent of the myocardial extracellular matrix in fibrosis.
Topics: Angiotensin II; Animals; Cells, Cultured; Desoxycorticosterone; Disease Models, Animal; Endomyocardial Fibrosis; Extracellular Matrix; Fibrillin-1; Fibrillins; Fibroblasts; Integrins; Male; Mice; Mice, Transgenic; Microfilament Proteins; Myocardium; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents | 2005 |
Effects of alpha-lipoic acid on kinin B1 and B2 receptor binding sites in the spinal cord of chronically angiotensin-treated rats.
Topics: Angiotensin II; Animals; Binding Sites; Blood Glucose; Blood Pressure; Body Weight; Chronic Disease; Diet; Disease Models, Animal; Insulin; Rats; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Spinal Cord; Superoxides; Thioctic Acid | 2005 |
The angiotensin II type 2 receptor and improved adjacent region function post-MI.
Topics: Angiotensin II; Animals; Collagen; Contrast Media; Disease Models, Animal; Gadolinium DTPA; Heart Ventricles; Image Processing, Computer-Assisted; Magnetic Resonance Imaging, Cine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocytes, Cardiac; Receptor, Angiotensin, Type 2; Stroke Volume; Systole; Ventricular Dysfunction, Left; Ventricular Remodeling | 2005 |
Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Body Weight; Deoxyguanosine; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin; Islets of Langerhans; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Tetrazoles; Time Factors; Valine; Valsartan | 2005 |
Glomerular permeability defect in hypertension is dependent on renin angiotensin system activation.
Topics: Albumins; Angiotensin II; Animals; Blood Pressure; Cell Membrane Permeability; Desoxycorticosterone; Disease Models, Animal; Follow-Up Studies; Glomerular Filtration Rate; Hypertension; Kidney Glomerulus; Male; Radioimmunoassay; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Wistar; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 2005 |
Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Aorta, Thoracic; Biopterins; Cardiomegaly; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Male; NADPH Oxidases; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides; Time Factors; Tyrosine; Up-Regulation | 2005 |
[Protective effects of taurine on myocardial injury in severely burned rats].
Topics: Angiotensin II; Animals; Burns; Calcium; Disease Models, Animal; Female; Male; Malondialdehyde; Myocardium; Rats; Rats, Wistar; Taurine; Troponin T; Tumor Necrosis Factor-alpha | 2005 |
Angiotensin-converting enzyme 2 protects from severe acute lung failure.
Topics: Acids; Acute Disease; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Capillary Permeability; Carboxypeptidases; Disease Models, Animal; Gene Deletion; Humans; Lung; Lung Diseases; Mice; Mice, Knockout; Mice, Transgenic; Oxygen; Peptidyl-Dipeptidase A; Pulmonary Edema; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Respiratory Distress Syndrome; Sepsis; Transgenes | 2005 |
Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Apolipoproteins E; Atherosclerosis; Chemokine CCL2; Disease Models, Animal; Female; Follow-Up Studies; Hyperlipidemias; Immunohistochemistry; Infusions, Intravenous; Mice; Mice, Inbred C57BL; Receptors, CCR2; Receptors, Chemokine; RNA | 2006 |
Blood pressure variability, cardiac baroreflex sensitivity and organ damage in experimentally hypertensive rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Blood Pressure Determination; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Hypertension; Hypertension, Renovascular; Interleukin-1; Kidney Glomerulus; Male; Myocardium; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Berberine inhibits rat vascular smooth muscle cell proliferation and migration in vitro and improves neointima formation after balloon injury in vivo. Berberine improves neointima formation in a rat model.
Topics: Angioplasty, Balloon; Angiotensin II; Animals; Aorta, Thoracic; Berberine; Blotting, Western; Carotid Artery Injuries; Carotid Artery, Common; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Epidermal Growth Factor; Heparin-binding EGF-like Growth Factor; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Tunica Intima | 2006 |
Hypertension in Page (cellophane-wrapped) kidney is due to interstitial nephritis.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cellophane; Disease Models, Animal; Glutathione; Hypertension, Renal; Immunosuppressive Agents; Ischemia; Kidney; Kidney Function Tests; Male; Malondialdehyde; Mycophenolic Acid; Nephritis, Interstitial; Pressure; Rats; Rats, Sprague-Dawley | 2005 |
Animal models of cardiac fibrosis.
Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Diseases; Heart Ventricles; Humans; Immunohistochemistry; In Situ Hybridization; Isoproterenol; Male; Myocardial Infarction; Myocardium; Phenotype; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2005 |
Pitavastatin inhibits cardiac hypertrophy in a rat model of progressive renal injury.
Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Kidney; Male; Myocytes, Cardiac; Nephrectomy; Phosphorylation; Quinolines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents | 2005 |
Transforming growth factor-beta1 upregulation is independent of angiotensin in paraquat-induced lung fibrosis.
Topics: Actins; Angiotensin II; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydroxyproline; Lung; Male; Microscopy, Polarization; Paraquat; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-myc; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Toxicity Tests; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2005 |
Angiotensin II sensitivity of afferent glomerular arterioles in endothelin-1 transgenic mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gene Expression; In Vitro Techniques; Kidney Glomerulus; Male; Mice; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Polymerase Chain Reaction; Receptors, Angiotensin; Renal Artery; Renin; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Mechanical stretch-induced hypertrophy of neonatal rat ventricular myocytes is mediated by beta(1)-integrin-microtubule signaling pathways.
Topics: Angiotensin II; Animals; Animals, Newborn; Antibodies; Cardiomegaly; Cells, Cultured; Colchicine; Disease Models, Animal; In Vitro Techniques; Integrin beta1; Microscopy, Confocal; Microtubules; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Mechanical | 2006 |
A centrally acting, anxiolytic angiotensin II AT1 receptor antagonist prevents the isolation stress-induced decrease in cortical CRF1 receptor and benzodiazepine binding.
Topics: Amphibian Proteins; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autoradiography; Behavior, Animal; Benzimidazoles; Benzodiazepines; Biphenyl Compounds; Cerebral Cortex; Disease Models, Animal; Flunitrazepam; GABA Modulators; In Situ Hybridization; Male; Maze Learning; Peptide Hormones; Peptides; Protein Binding; Pyrimidines; Pyrroles; Rats; Receptor, Angiotensin, Type 2; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Social Isolation; Stress, Physiological; Tetrazoles; Tyrosine 3-Monooxygenase | 2006 |
Nephron function in transgenic mice with selective vascular or tubular expression of Angiotensin-converting enzyme.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Female; Glomerular Filtration Rate; Immunohistochemistry; Injections, Intravenous; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Nephrons; Peptidyl-Dipeptidase A; Species Specificity | 2005 |
Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice.
Topics: Angiotensin II; Animals; Biological Availability; Blood Pressure; Disease Models, Animal; Heart Rate; Hypertension; Mice; Mice, Inbred Strains; Mice, Knockout; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide; Reactive Oxygen Species | 2005 |
Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis.
Topics: Actins; Angiotensin II; Animals; Atrophy; Crotalid Venoms; Disease Models, Animal; Epithelial Cells; Extracellular Matrix; Fibroblasts; Fibrosis; Kidney; Kidney Diseases; Kidney Tubules; Male; Microscopy, Electron; Microscopy, Fluorescence; Myocytes, Smooth Muscle; Rats; Sodium-Potassium-Exchanging ATPase | 2005 |
[Study of effects of drugs on myocardial hypertrophy due to overload].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Carbazoles; Disease Models, Animal; Endothelin-1; Hypertrophy, Left Ventricular; Imidazolidines; Myocardium; Propanolamines; Random Allocation; Rats; Tumor Necrosis Factor-alpha | 2005 |
Angiotensin II-dependent vascular alterations in young cardiomyopathic hamsters: role for oxidative stress.
Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aorta; Blood Pressure; Cardiomyopathies; Cricetinae; Disease Models, Animal; Losartan; Male; Mesocricetus; NADPH Oxidases; Oxidative Stress; Superoxides | 2006 |
Angiotensin II and endothelin in the renal cortex during the evolution of glycerol-induced acute tubular necrosis.
Topics: Analysis of Variance; Angiotensin II; Animals; Biomarkers; Biopsy, Needle; Disease Models, Animal; Endothelins; Glycerol; Immunohistochemistry; Kidney Cortex; Kidney Function Tests; Kidney Tubular Necrosis, Acute; Male; Microscopy; Probability; Random Allocation; Rats; Rats, Wistar; Risk Factors; Sensitivity and Specificity | 2005 |
Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding.
Topics: Angiotensin II; Animals; Aortic Valve Stenosis; Biomarkers; Cardiomegaly; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2006 |
Angiotensin II via AT1 receptor accelerates arterial thrombosis in renovascular hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Artery Thrombosis; Carotid Artery, Common; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Fibrinolysis; Hemostasis; Hypertension, Renovascular; Infusions, Intravenous; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Time Factors; Vasoconstrictor Agents | 2005 |
Effect of tempol on altered angiotensin II and acetylcholine-mediated vascular responses in thoracic aorta isolated from rats with insulin resistance.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cyclic N-Oxides; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Insulin Resistance; Male; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Renal vascular responses in an experimental model of preeclampsia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Coarctation; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Losartan; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation | 2005 |
Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells.
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Blood Glucose; Cells, Cultured; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Janus Kinase 2; Male; Mesangial Cells; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Signal Transduction; Simvastatin; STAT1 Transcription Factor; STAT3 Transcription Factor; Terpenes | 2006 |
Increased vascular angiotensin II binding capacity and ET-1 release in young cardiomyopathic hamsters.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Binding, Competitive; Cardiomyopathies; Cricetinae; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin-1; In Vitro Techniques; Losartan; Male; Mesocricetus; Peptides, Cyclic; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Neuronal nitric oxide synthase and cyclooxygenase-2 in diabetic nephropathy of type 2 diabetic OLETF rats.
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Kidney; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Long-Evans; Renin | 2006 |
Prevention and reversal by enalapril of target organ damage in angiotensin II hypertension.
Topics: Acetophenones; Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Enalapril; Hypertension; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2005 |
Effects of enalapril, tempol, and eplerenone on salt-induced hypertension in dahl salt-sensitive rats.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enalapril; Eplerenone; Epoprostenol; Hypertension; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred Dahl; Sodium Chloride; Spin Labels; Spironolactone; Treatment Outcome | 2006 |
Cardiac remodeling and angiotensin II-forming enzyme activity of the left ventricle in hamsters with chronic pressure overload induced by ascending aortic stenosis.
Topics: Angiotensin II; Animals; Aortic Valve Stenosis; Body Weight; Chymases; Cricetinae; Disease Models, Animal; Dog Diseases; Dogs; Echocardiography; Heart Failure; Heart Ventricles; Histocytochemistry; Male; Mesocricetus; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Serine Endopeptidases; Ventricular Remodeling | 2006 |
Oxidant stress and blood pressure responses to angiotensin II administration in rats fed varying salt diets.
Topics: Acetophenones; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Diet, Sodium-Restricted; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Infusions, Intravenous; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents | 2006 |
Time course analysis of tyrosine hydroxylase and angiotensinogen mRNA expression in central nervous system of rats submitted to experimental hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Aortic Coarctation; Blood Pressure; Brain; Brain Stem; Catecholamines; Disease Models, Animal; Gene Expression; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred WKY; RNA, Messenger; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation | 2006 |
Loss of angiotensin-converting enzyme-2 leads to the late development of angiotensin II-dependent glomerulosclerosis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Collagen; Disease Models, Animal; Female; Fibronectins; Glomerulosclerosis, Focal Segmental; Kidney Diseases; Kidney Glomerulus; Male; MAP Kinase Signaling System; Mice; Mice, Transgenic; Peptidyl-Dipeptidase A | 2006 |
Enhanced sensitivity of Kv channels to hypoxia in the rabbit carotid body in heart failure: role of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Body; Cell Hypoxia; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Failure; Imidazoles; Male; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Rabbits; Tetrazoles | 2006 |
Regulation of angiogenic factors in angiotensin II infusion model in association with tubulointerstitial injuries.
Topics: Angiopoietin-1; Angiopoietin-2; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Infusions, Parenteral; Kidney Diseases; Kidney Tubules; Macrophages; Male; Monocytes; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; Vascular Endothelial Growth Factor A | 2006 |
Lack of flow-mediated dilation and enhanced angiotensin II-induced constriction in skeletal muscle arterioles of lupus-prone autoimmune mice.
Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Antibodies, Antinuclear; Arterioles; Blood Pressure; Bradykinin; Disease Models, Animal; Endothelium, Vascular; Female; Hemorheology; Lupus Erythematosus, Systemic; Mice; Mice, Inbred MRL lpr; Muscle, Skeletal; Nitroprusside; Serotonin; Vasoconstriction; Vasodilation; Vasodilator Agents | 2006 |
The inhibitory effect of leptin on angiotensin II-induced vasoconstriction is blunted in spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta; Biomarkers; Blotting, Western; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Leptin; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Isoforms; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Cell Surface; Receptors, Leptin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstriction | 2006 |
Irbesartan restores the in-vivo insulin signaling pathway leading to Akt activation in obese Zucker rats.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Enzyme Activation; Fatty Liver; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Irbesartan; Male; Mitogen-Activated Protein Kinase 3; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetrazoles | 2006 |
Angiotensin II induces histomorphologic features of unstable plaque in a murine model of accelerated atherosclerosis.
Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Chemokine CCL2; Disease Models, Animal; Foam Cells; Immunohistochemistry; Ligation; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Tunica Intima; Vascular Cell Adhesion Molecule-1 | 2006 |
Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway.
Topics: Aging, Premature; Angiotensin II; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cells, Cultured; Disease Models, Animal; Genes, Reporter; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Transfection | 2006 |
Chronic low-dose angiotensin II infusion increases venomotor tone by neurogenic mechanisms.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sympathetic Nervous System; Venous Pressure | 2006 |
The role of angiotensin II in stress urinary incontinence: A rat model.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Female; Imidazoles; Losartan; Peripheral Nerve Injuries; Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Urethra; Urinary Bladder; Urinary Incontinence, Stress; Vasoconstrictor Agents | 2007 |
Cerebroprotective effect of angiotensin IV in experimental ischemic stroke in the rat mediated by AT(4) receptors.
Topics: Analysis of Variance; Angiotensin II; Animals; Brain; Brain Ischemia; Cerebral Angiography; Disease Models, Animal; Dose-Response Relationship, Drug; Intracranial Embolism; Male; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Regional Blood Flow; Stroke; Vasoconstriction | 2006 |
The nonpeptide angiotensin-(1-7) receptor Mas agonist AVE-0991 attenuates heart failure induced by myocardial infarction.
Topics: Angiotensin II; Animals; Cardiac Output, Low; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Rate; Heart Ventricles; Imidazoles; Ligation; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Time Factors; Vasoconstriction; Vasodilator Agents; Ventricular Function, Left | 2007 |
Effects of angiotensin II on NO bioavailability evaluated using a catheter-type NO sensor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Catheterization; Cyclic N-Oxides; Disease Models, Animal; Hydralazine; Male; Nitric Oxide; Oxidants; Oxidative Stress; Rabbits; Spin Labels; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Chronic angiotensin II stimulation in the heart produces an acquired long QT syndrome associated with IK1 potassium current downregulation.
Topics: Action Potentials; Angiotensin II; Animals; Base Sequence; Cardiomegaly; Disease Models, Animal; DNA Primers; Down-Regulation; Electrocardiography; Humans; In Vitro Techniques; Intermediate-Conductance Calcium-Activated Potassium Channels; Long QT Syndrome; Male; Mice; Mice, Transgenic; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; RNA, Messenger | 2007 |
Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Genetic Vectors; Hypertension; Imidazoles; Losartan; Male; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Time Factors; Transduction, Genetic; Up-Regulation | 2007 |
Discoidin domain receptor 1 null mice are protected against hypertension-induced renal disease.
Topics: Angiotensin II; Animals; Chemokine CCL2; Collagen Type I; Collagen Type IV; Cytokines; Discoidin Domain Receptors; Disease Models, Animal; Fibrosis; Hypertension; Inflammation; Kidney Failure, Chronic; Kidney Glomerulus; Lipopolysaccharides; Male; Mice; Mice, Transgenic; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; Shock, Septic; Vasoconstrictor Agents | 2006 |
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7).
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart; Hypertension; Male; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Time Factors; Transforming Growth Factor beta; Ventricular Remodeling | 2007 |
Telmisartan attenuates chronic ciclosporin A nephrotoxicity in a pig model.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Biopsy; Blood Flow Velocity; Blood Pressure; Cyclosporine; Disease Models, Animal; Female; Follow-Up Studies; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Failure, Chronic; Magnetic Resonance Imaging; Renal Circulation; Swine; Telmisartan; Treatment Outcome | 2007 |
Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Bradykinin; Chronic Disease; Cyclic N-Oxides; Dinoprost; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enalapril; Hydrogen Peroxide; Hypertension; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Spin Labels; Superoxides; Time Factors | 2007 |
Forced swimming test increases superoxide anion positive cells and angiotensin II positive cells in the cerebrum and cerebellum of the rat.
Topics: Angiotensin II; Animals; Body Weight; Brain; Cell Count; Cerebellum; Cerebral Arteries; Depressive Disorder; Disease Models, Animal; Endothelial Cells; Immunohistochemistry; Male; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stress, Psychological; Superoxides; Swimming; Telencephalon; Up-Regulation | 2006 |
Blood pressure early in diabetes depends on a balance between glomerular filtration rate and the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Nephrectomy; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium; Time Factors | 2006 |
Endogenous angiotensin II enhances atherogenesis in apoprotein E-deficient mice with renovascular hypertension through activation of vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Cell Line; Culture Media, Conditioned; Disease Models, Animal; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Foam Cells; Gene Silencing; Hypertension, Renovascular; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Sinus of Valsalva | 2007 |
Combined effects of low-dose spironolactone and captopril therapy in a rat model of genetic hypertrophic cardiomyopathy.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Congenic; Atrial Natriuretic Factor; Blood Pressure; Captopril; Cardiomyopathy, Hypertrophic; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Injections, Subcutaneous; Myocardium; Organ Size; Random Allocation; Rats; Rats, Inbred Strains; Spironolactone; Ventricular Function, Left; Weight Loss | 2006 |
p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Cardiovascular Diseases; Disease Models, Animal; Kidney Diseases; Male; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyrazoles; Rats; Rats, Sprague-Dawley; Renin | 2007 |
Adapter molecule DOC-2 is differentially expressed in pressure and volume overload hypertrophy and inhibits collagen synthesis in cardiac fibroblasts.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Aorta, Abdominal; Arteriovenous Shunt, Surgical; Cardiomegaly; Cells, Cultured; Collagen; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gene Expression; Ligation; Myocytes, Cardiac; Phorbol Esters; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Transfection; Ventricular Remodeling | 2007 |
Lack of macrophage migration inhibitory factor regulation is linked to the increased chronotropic action of angiotensin II in SHR neurons.
Topics: Angiotensin II; Animals; Brain Stem; Cells, Cultured; Disease Models, Animal; Female; Hypertension; Hypothalamus; Macrophage Migration-Inhibitory Factors; Male; Neurons; Periodicity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Thrombopoietin | 2007 |
Involvement of endogenous ouabain-like compound in the cardiac hypertrophic process in vivo.
Topics: Adrenalectomy; Angiotensin II; Animals; Atrial Natriuretic Factor; Blotting, Northern; Cardenolides; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; Norepinephrine; Organ Size; Rats; Rats, Sprague-Dawley; RNA, Messenger; Saponins; Up-Regulation; Vasoconstrictor Agents | 2007 |
PTEN reduces cuff-induced neointima formation and proinflammatory cytokines.
Topics: Adenoviridae; Angiotensin II; Animals; Apoptosis; Atherosclerosis; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Cytokines; Disease Models, Animal; Femoral Artery; Genetic Therapy; Genetic Vectors; I-kappa B Proteins; Inflammation; Interleukin-1beta; Macrophages; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-KappaB Inhibitor alpha; Phosphorylation; PTEN Phosphohydrolase; Rats; Rats, Wistar; RNA, Messenger; Transfection; Tumor Necrosis Factor-alpha; Tunica Intima | 2007 |
Angiotensin II mediates postischemic leukocyte-endothelial interactions: role of calcitonin gene-related peptide.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcitonin Gene-Related Peptide; Captopril; Cell Adhesion; Chymases; Disease Models, Animal; Endothelial Cells; Imidazoles; Intestines; Ischemia; Leukocyte Rolling; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; NADPH Oxidases; Pyridines; Pyrimidinones; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Calcitonin Gene-Related Peptide; Reperfusion Injury; Tetrazoles; Valine; Valsartan; Venules | 2007 |
Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Cardiomegaly; Disease Models, Animal; Half-Life; Hypertension; Imidazoles; Kinetics; Leucine; Male; Mice; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin | 2007 |
ERK activation contributes to regulation of spontaneous contractile tone via superoxide anion in isolated rat aorta of angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Butadienes; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Flavonoids; Hypertension; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Superoxides; Vasoconstriction | 2007 |
Angiotensin II, focal adhesion kinase, and PRX1 enhance smooth muscle expression of lipoma preferred partner and its newly identified binding partner palladin to promote cell migration.
Topics: Actins; Angiotensin II; Animals; Aorta; Blotting, Western; Cell Line; Cell Movement; Cytoskeletal Proteins; Disease Models, Animal; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gene Expression Regulation; Gene Transfer Techniques; Homeodomain Proteins; Humans; LIM Domain Proteins; Mice; Muscle, Smooth, Vascular; Organ Specificity; Phosphoproteins; Protein Structure, Tertiary; Pseudopodia; Rats; Rats, Sprague-Dawley; Two-Hybrid System Techniques | 2007 |
Contribution of different Nox homologues to cardiac remodeling in two-kidney two-clip renovascular hypertensive rats: effect of valsartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension, Renovascular; Ligation; Male; Malondialdehyde; Membrane Glycoproteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Renal Artery; Superoxides; Tetrazoles; Valine; Valsartan; Ventricular Function, Left; Ventricular Remodeling | 2007 |
Influence of transplantation of allogenic bone marrow mononuclear cells on the left ventricular remodeling of rat after acute myocardial infarction.
Topics: Angiotensin II; Animals; Bone Marrow Transplantation; Collagen Type I; Disease Models, Animal; Leukocytes, Mononuclear; Male; Myocardial Infarction; Osteopontin; Rats; Rats, Wistar; Ventricular Remodeling | 2006 |
PPAR gamma agonists partially restores hyperglycemia induced aggravation of vascular dysfunction to angiotensin II in thoracic aorta isolated from rats with insulin resistance.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Male; Pioglitazone; PPAR gamma; Prediabetic State; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Rosiglitazone; Streptozocin; Thiazolidinediones; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Angiotensin II-induced sudden arrhythmic death and electrical remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cardiac Pacing, Artificial; Cardiomegaly; Connexin 43; Death, Sudden, Cardiac; Disease Models, Animal; Electrocardiography; Heart Conduction System; Hypertension; Losartan; Male; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Shal Potassium Channels; Tachycardia, Ventricular; Telemetry; Time Factors; Ventricular Remodeling | 2007 |
An angiotensin II receptor blocker increases sexual behavior in type 2 diabetic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Exploratory Behavior; Female; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Inbred Strains; Motor Activity; Reaction Time; Receptor, Angiotensin, Type 1; Sexual Behavior, Animal; Sexual Dysfunction, Physiological; Species Specificity; Tetrazoles; Time Factors | 2007 |
Genetic and dietary interactions: role of angiotensin AT1a receptors in response to a high-fructose diet.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Circadian Rhythm; Dietary Carbohydrates; Disease Models, Animal; Fructose; Glucose Intolerance; Heart Rate; Hypertension; Insulin Resistance; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prazosin; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha-1; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System; Time Factors | 2007 |
Novel mechanisms of valsartan on the treatment of acute myocardial infarction through inhibition of the antiadhesion molecule periostin.
Topics: Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Cell Adhesion Molecules; Cell Communication; Cells, Cultured; Disease Models, Animal; Fibroblasts; Gene Expression Regulation; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Random Allocation; Rats; Rats, Inbred Lew; Rats, Wistar; Stress, Mechanical; Tetrazoles; Valine; Valsartan; Ventricular Remodeling | 2007 |
Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation.
Topics: Aldosterone; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Body Weight; Cytokines; Disease Models, Animal; Eplerenone; Female; Fibroblasts; Fibrosis; Hypertension; Immunohistochemistry; In Situ Hybridization; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Inbred BALB C; Mineralocorticoid Receptor Antagonists; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; Spironolactone; Tenascin; Up-Regulation; Vasoconstrictor Agents | 2007 |
Increased inhibition of inward rectifier K+ channels by angiotensin II in small-diameter coronary artery of isoproterenol-induced hypertrophied model.
Topics: Angiotensin II; Animals; Blotting, Western; Cardiomyopathy, Hypertrophic; Cells, Cultured; Coronary Vessels; Disease Models, Animal; Electrophysiology; Endothelium, Vascular; Male; Muscle, Smooth, Vascular; Potassium Channels, Inwardly Rectifying; Probability; Rabbits; Random Allocation; Reference Values; Sensitivity and Specificity; Vasoconstrictor Agents; Vasodilation | 2007 |
The significance of chymase in the progression of abdominal aortic aneurysms in dogs.
Topics: Acetamides; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Count; Chymases; Disease Models, Animal; Disease Progression; Dogs; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neutrophils; Pyrimidines; Tunica Media; Ultrasonography | 2007 |
Angiotensin II plays a role in acute murine experimental autoimmune cystitis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Autoimmune Diseases; Cystitis, Interstitial; Disease Models, Animal; Female; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Treatment Outcome | 2007 |
Effect of chronic IL-6 infusion on acute pressor responses to vasoconstrictors in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Heart Rate; Hypertension; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pressoreceptors; Vasoconstrictor Agents | 2007 |
Effects of acute stress on the day of proestrus on sexual behavior and ovulation in female rats: participation of the angiotensinergic system.
Topics: Acute Disease; Analysis of Variance; Angiotensin II; Animals; Circadian Rhythm; Corticosterone; Disease Models, Animal; Female; Luteinizing Hormone; Oocytes; Ovulation; Proestrus; Progesterone; Prolactin; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sexual Behavior, Animal; Statistics, Nonparametric; Stress, Psychological | 2007 |
[Relationship between angiotensin converting enzyme gene and ischemic stroke].
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Asphyxia; Brain Ischemia; Disease Models, Animal; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypoxia; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Risk Factors; Stroke | 2007 |
HMG-CoA reductase inhibitors decrease angiotensin II-induced vascular fibrosis: role of RhoA/ROCK and MAPK pathways.
Topics: Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Connective Tissue Growth Factor; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Sensitivity and Specificity; Signal Transduction | 2007 |
Self-terminating AF depends on electrical remodeling while persistent AF depends on additional structural changes in a rapid atrially paced sheep model.
Topics: Angiotensin II; Animals; Atrial Fibrillation; Bundle of His; Cardiac Output; Cardiac Pacing, Artificial; Disease Models, Animal; Female; Kaplan-Meier Estimate; Matrix Metalloproteinases; Myocytes, Cardiac; Refractory Period, Electrophysiological; Renin-Angiotensin System; Sheep; Time Factors; Tissue Inhibitor of Metalloproteinases | 2007 |
Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function.
Topics: Angiotensin I; Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Erectile Dysfunction; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Sodium Chloride, Dietary; Vasodilator Agents | 2007 |
Assessing bias in experiment design for large scale mass spectrometry-based quantitative proteomics.
Topics: Angiotensin II; Animals; Bias; Biomarkers; Cell Cycle; Chromatography, Liquid; Disease Models, Animal; Freezing; Humans; Huntington Disease; Mass Spectrometry; Mice; Proteomics; Reproducibility of Results; Research Design; Saccharomyces cerevisiae; Time Factors | 2007 |
Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Congenic; Blood Pressure; C-Reactive Protein; Cell Adhesion Molecules; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Membrane Proteins; Ovariectomy; Peptide Fragments; Proteinuria; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 2007 |
Renal inflammation is modulated by potassium in chronic kidney disease: possible role of Smad7.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Chronic Disease; Creatinine; Disease Models, Animal; Kidney; Kidney Diseases; Male; Nephritis; NF-kappa B; Potassium; Potassium, Dietary; Rats; Rats, Sprague-Dawley; Smad7 Protein; Sodium; Transforming Growth Factor beta | 2007 |
Regulator of G protein signalling 2 ameliorates angiotensin II-induced hypertension in mice.
Topics: Angiotensin II; Animals; Arterioles; Baroreflex; Blood Pressure; Disease Models, Animal; Endothelin-1; Epinephrine; Heart Rate; Hypertension; Male; Mice; Mice, Knockout; Norepinephrine; Phenylephrine; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RGS Proteins; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Angiotensin II provokes podocyte injury in murine model of HIV-associated nephropathy.
Topics: AIDS-Associated Nephropathy; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Gene Products, vpr; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Transgenic; Norepinephrine; Phenotype; Podocytes; Receptor, Angiotensin, Type 1 | 2007 |
Antiangiogenic role of somatostatin receptor 2 in a model of hypoxia-induced neovascularization in the retina: results from transgenic mice.
Topics: Angiotensin I; Angiotensin II; Animals; Capillaries; Disease Models, Animal; Hypoxia; Insulin-Like Growth Factor I; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Receptor, IGF Type 1; Receptor, TIE-1; Receptor, TIE-2; Receptors, Somatostatin; Retinal Diseases; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2007 |
Reduced cardiovascular reactivity to stress but not feeding in renin enhancer knockout mice.
Topics: Acetylcholine; Angiotensin II; Animal Feed; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Heart Rate; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Renin; Restraint, Physical; Risk Factors; Stress, Psychological; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Hepatic conversion of angiotensin I and the portal hypertensive response to angiotensin II in normal and regenerating liver.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Hypertension, Portal; Kinetics; Liver; Liver Circulation; Liver Regeneration; Rats; Rats, Wistar | 2007 |
Obesity augments vasoconstrictor reactivity to angiotensin II in the renal circulation of the Zucker rat.
Topics: Angiotensin II; Animals; Blood Pressure; Diet, Sodium-Restricted; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Insulin Resistance; Kidney Diseases; Mesenteric Artery, Superior; Norepinephrine; Obesity; Prediabetic State; Rats; Rats, Zucker; Renal Artery; Renal Circulation; Renin; Renin-Angiotensin System; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Angiotensin II receptor blocker inhibits neointimal hyperplasia through regulation of smooth muscle-like progenitor cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Femoral Artery; Humans; Imidazoles; Mice; Mice, Transgenic; Myocytes, Smooth Muscle; Peripheral Vascular Diseases; Pyridines | 2007 |
Plasticity and impact of the central renin-angiotensin system during development of ethanol dependence.
Topics: Adaptation, Physiological; Alcoholism; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Genetically Modified; Central Nervous System; Disease Models, Animal; Enalapril; Ethanol; Humans; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Antisense | 2007 |
Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage.
Topics: Angiotensin II; Animals; Autoradiography; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Endothelin B; Receptor, Serotonin, 5-HT1B; RNA, Messenger; Serotonin; Subarachnoid Hemorrhage; Time Factors; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Angiotensin II receptors subtypes mediate diverse gene expression profile in adult hypertrophic cardiomyocytes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Imidazoles; Interleukin-1beta; Interleukin-6; Ligation; Losartan; Male; Myocytes, Cardiac; Oligonucleotide Array Sequence Analysis; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Effects of resibufogenin in experimental hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Bufanolides; Creatinine; Desoxycorticosterone; Disease Models, Animal; Hypertension, Renal; Male; Mineralocorticoids; Proteinuria; Rats; Rats, Inbred Strains; Sodium Chloride; Superoxides; Vasoconstrictor Agents | 2008 |
Absence of peroxisome proliferator-activated receptor-alpha abolishes hypertension and attenuates atherosclerosis in the Tsukuba hypertensive mouse.
Topics: Aldosterone; Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Cardiomegaly; Diet, Atherogenic; Disease Models, Animal; Fenofibrate; Genotype; Humans; Hypertension; Hypolipidemic Agents; Mice; Mice, Knockout; Mice, Transgenic; PPAR alpha; Renin; Renin-Angiotensin System | 2007 |
Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis.
Topics: Alanine Transaminase; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aspartate Aminotransferases; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Choline Deficiency; Disease Models, Animal; DNA Damage; Fatty Liver; Liver; Liver Cirrhosis; Male; Organ Size; Oxidative Stress; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Signal Transduction; Tetrazoles; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Effects of angiotensin II blockade on the development of autoimmune thyroiditis in nonobese diabetic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Enalapril; Hashimoto Disease; Losartan; Mice; Mice, Inbred NOD; Sodium Iodide; Thyroglobulin | 2008 |
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.
Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Biopterins; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Endothelium, Vascular; Heart Failure, Diastolic; Hydralazine; Hypertension; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilation | 2007 |
Renal interstitial adenosine is increased in angiotensin II-induced hypertensive rats.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney Cortex; Male; Proteinuria; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; RNA, Messenger; Vasoconstrictor Agents | 2008 |
The progression of inflammation parallels the dermal angiogenesis in a keratin 14 IL-4-transgenic model of atopic dermatitis.
Topics: Angiotensin I; Angiotensin II; Animals; Antigens, CD; Cadherins; Cells, Cultured; Dermatitis, Atopic; Dermis; Disease Models, Animal; GTP-Binding Proteins; Interferon-gamma; Interleukin-4; Interleukin-6; Keratin-14; Keratinocytes; Mice; Mice, Transgenic; Microcirculation; Neovascularization, Pathologic; Up-Regulation; Vascular Endothelial Growth Factor A | 2008 |
A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protease Inhibitors; Rats; Sulfonamides | 2008 |
ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin.
Topics: Angiotensin II; Animals; Apoptosis; Bradykinin; Bronchoalveolar Lavage Fluid; Captopril; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation Mediators; Losartan; Lung Diseases; Male; Peptidyl-Dipeptidase A; Pulmonary Gas Exchange; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Respiration, Artificial; Sensitivity and Specificity | 2008 |
NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells.
Topics: Acetophenones; Actins; Angiotensin II; Animals; Becaplermin; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Chemokine CXCL1; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibrosis; Humans; Interleukin-1beta; Male; Mitogen-Activated Protein Kinases; NADPH Oxidases; NF-kappa B; Onium Compounds; Organotin Compounds; Pancreas; Pancreatitis, Chronic; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Inbred Lew; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Time Factors; Transcription Factor AP-1; Transfection | 2008 |
The mechanistic basis for the disparate effects of angiotensin II on coronary collateral growth.
Topics: Angiotensin II; Animals; Coronary Occlusion; Disease Models, Animal; Hemorheology; Ischemia; Male; Neovascularization, Physiologic; Oxidative Stress; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Vasoconstrictor Agents | 2008 |
Critical role of bone marrow angiotensin II type 1 receptor in the pathogenesis of atherosclerosis in apolipoprotein E deficient mice.
Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Bone Marrow Transplantation; Disease Models, Animal; Male; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1; Transplantation Chimera | 2008 |
Role of angiotensin II in endothelial dysfunction induced by lipopolysaccharide in mice.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; Endotoxemia; Imidazoles; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Nitroprusside; Oxidative Stress; Renin-Angiotensin System; Superoxides; Tetrazoles; Vasodilation; Vasodilator Agents | 2007 |
ACE2 and ANG-(1-7) in the rat uterus during early and late gestation.
Topics: Amnion; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Decidua; Disease Models, Animal; Epithelial Cells; Female; Hypertension, Pregnancy-Induced; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Uterus; Yolk Sac | 2008 |
The role of local and systemic renin angiotensin system activation in a genetic model of sympathetic hyperactivity-induced heart failure in mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Heart Failure; Heart Rate; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Genetic; Myocytes, Cardiac; Norepinephrine; Physical Conditioning, Animal; Receptors, Adrenergic, alpha-2; Renin-Angiotensin System; Sympathetic Nervous System | 2008 |
The neurovascular dysfunction induced by angiotensin II in the mouse neocortex is sexually dimorphic.
Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Disease Susceptibility; Estradiol; Estrogen Replacement Therapy; Female; Hypertension; Infusion Pumps, Implantable; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Neocortex; Ovariectomy; Reflex; Sex Factors; Stroke; Time Factors; Vasodilator Agents; Vibrissae | 2008 |
Purinergic receptors contribute to early mesangial cell transformation and renal vessel hypertrophy during angiotensin II-induced hypertension.
Topics: Actins; Adenosine Triphosphate; Angiotensin II; Animals; Arterioles; Blood Pressure; Cell Proliferation; Clopidogrel; Disease Models, Animal; Hypertension; Hypertrophy; Kidney; Male; Membrane Proteins; Mesangial Cells; Purinergic Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Renin; Ticlopidine | 2008 |
Ultrastructural islet study of early fibrosis in the Ren2 rat model of hypertension. Emerging role of the islet pancreatic pericyte-stellate cell.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Glucose; Blood Pressure; Body Weight; Cell Communication; Disease Models, Animal; Extracellular Matrix; Fibrosis; Hypertension; Islets of Langerhans; Male; Oxidative Stress; Pericytes; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2007 |
Effects of p38 mitogen-activated protein kinase inhibition on blood pressure, renal hemodynamics, and renal vascular reactivity in normal and diabetic rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Glomerular Filtration Rate; Hemodynamics; Kidney Function Tests; Male; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Renin; Streptozocin; Vascular Resistance; Vasoconstriction; Vasodilation | 2007 |
Rapid development of severe end-organ damage in C57BL/6 mice by combining DOCA salt and angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Disease Models, Animal; Hypertension; Kidney Failure, Chronic; Kidney Glomerulus; Male; Mice; Mineralocorticoids; Myocardium; Proteinuria; Vasoconstrictor Agents | 2008 |
Pressor and non-pressor effects of sodium loading on stroke in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Brain; Disease Models, Animal; Female; Heart Rate; Hypertension; Interleukin-1beta; Interleukin-6; Intracranial Aneurysm; Rats; Rats, Inbred SHR; Regression Analysis; Sodium Chloride, Dietary; Stroke; Time Factors; Tumor Necrosis Factor-alpha | 2008 |
"Don't flog the heart!" - development of specific drug therapies for heart failure.
Topics: Angiotensin II; Animals; Disease Models, Animal; Heart Failure; Humans; Myocardial Contraction; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Receptors, Adrenergic, beta-3; Renin-Angiotensin System; Sodium-Potassium-Exchanging ATPase; Up-Regulation | 2007 |
Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in mice.
Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Female; Hypercholesterolemia; Interleukin-4; Male; Mice; Mice, Mutant Strains; Receptors, LDL | 2007 |
Exercise training enhances baroreflex sensitivity by an angiotensin II-dependent mechanism in chronic heart failure.
Topics: Angiotensin II; Animals; Baroreflex; Chronic Disease; Disease Models, Animal; Down-Regulation; Exercise Therapy; Heart Failure; Hemodynamics; Infusion Pumps, Implantable; Kidney; Male; Medulla Oblongata; Nitroprusside; Phenylephrine; Physical Conditioning, Animal; Rabbits; Receptor, Angiotensin, Type 1; RNA, Messenger; Sympathetic Nervous System; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
[Expression of angiotensin converting enzyme and angiotensin II receptor in rabbits with hyperthyroid cardiomyopathy].
Topics: Angiotensin II; Animals; Cardiomyopathies; Disease Models, Animal; Female; Hyperparathyroidism; Male; Myocardium; Peptidyl-Dipeptidase A; Rabbits; Random Allocation; Receptors, Angiotensin; RNA, Messenger | 2007 |
Angiotensin II and new vessel formation: aiming for the right oxidative window.
Topics: Angiotensin II; Animals; Disease Models, Animal; Ischemia; Neovascularization, Physiologic; Oxidative Stress; Rats | 2008 |
Exercise training in heart failure: reduction in angiotensin II, sympathetic nerve activity, and baroreflex control.
Topics: Angiotensin II; Animals; Baroreflex; Chronic Disease; Disease Models, Animal; Down-Regulation; Exercise Therapy; Heart Failure; Hemodynamics; Humans; Kidney; Medulla Oblongata; Receptor, Angiotensin, Type 1; RNA, Messenger; Sympathetic Nervous System | 2008 |
Knockout of beta(1)- and beta(2)-adrenoceptors attenuates pressure overload-induced cardiac hypertrophy and fibrosis.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Aorta; Blood Pressure; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Genotype; Hypertrophy, Left Ventricular; Inflammation; Intercellular Signaling Peptides and Proteins; Ligation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Phenotype; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Signal Transduction; Time Factors; Ventricular Function, Left | 2008 |
Pravastatin attenuates left ventricular remodeling and diastolic dysfunction in angiotensin II-induced hypertensive mice.
Topics: Angiotensin II; Animals; Blood Pressure; Cholesterol; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Failure, Diastolic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Pravastatin; rho-Associated Kinases; Ventricular Remodeling | 2008 |
New twist to the role of the renin-angiotensin system in heart failure: aldosterone upregulates renin-angiotensin system components in the brain.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Disease Models, Animal; Heart Failure; Hemostasis; Rats; Renin-Angiotensin System; Up-Regulation | 2008 |
Hyperinsulinemic rats are normotensive but sensitized to angiotensin II.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Disease Models, Animal; Female; Ganglia, Sympathetic; Ganglionic Blockers; Glucose; Heart Rate; Hexamethonium; Hyperinsulinism; Hypertension; Insulin; Insulin Infusion Systems; Losartan; Myography; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Telemetry; Time Factors; Vasodilation; Vasodilator Agents | 2008 |
Sympathetic nerve activity in the superior cervical ganglia increases in response to imposed increases in arterial pressure.
Topics: Action Potentials; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Catheterization; Cerebral Arteries; Cerebral Veins; Cerebrovascular Circulation; Disease Models, Animal; Epinephrine; Humans; Hypertension; Hypotension; Male; Microelectrodes; Nitroprusside; Phenylephrine; Sheep; Superior Cervical Ganglion; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Does aldosterone upregulate the brain renin-angiotensin system in rats with heart failure?
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Disease Models, Animal; Heart Failure; Hemostasis; Hypothalamus; Male; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Renin-Angiotensin System; Superoxides; Up-Regulation | 2008 |
ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats.
Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Disease Models, Animal; Fatty Liver; Interleukin-6; Irbesartan; Liver; Liver Cirrhosis; Male; Metabolic Syndrome; Obesity; Perindopril; Rats; Rats, Zucker; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2008 |
Pioglitazone opposes neurogenic vascular dysfunction associated with chronic hyperinsulinaemia.
Topics: Administration, Oral; Angiotensin II; Animals; Blood Glucose; Blood Pressure; Chronic Disease; Disease Models, Animal; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Norepinephrine; Pioglitazone; Random Allocation; Rats; Rats, Wistar; Thiazolidinediones; Triglycerides; Vasoconstriction | 2008 |
Whole body norepinephrine kinetics in ANG II-salt hypertension in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Heart Rate; Hypertension; Infusion Pumps, Implantable; Kinetics; Male; Norepinephrine; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Sympathetic Nervous System; Tritium | 2008 |
Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1.
Topics: Angiotensin II; Animals; Antibodies; Carotid Artery Diseases; Catheterization; Cells, Cultured; Disease Models, Animal; Humans; Lymphokines; Muscle, Smooth, Vascular; Mutagenesis; Phosphorylation; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein Kinase C; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Serine; Sp1 Transcription Factor; Spectrometry, Mass, Electrospray Ionization; Threonine; Transcription, Genetic; Vasoconstrictor Agents; Zinc Fingers | 2008 |
Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Calcium-Binding Proteins; Calpain; Cysteine Proteinase Inhibitors; Disease Models, Animal; Fibrosis; Genetic Therapy; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; Inflammation; Infusion Pumps, Implantable; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocardium; NF-kappa B; NFATC Transcription Factors; Renal Artery; Time Factors; Ventricular Remodeling | 2008 |
Age- and sodium-sensitive hypertension and sex-dependent renal changes in rats with a reduced nephron number.
Topics: Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Dietary Proteins; Disease Models, Animal; Female; Glomerular Filtration Rate; Hypertension, Renal; Male; Nephrons; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sex Factors; Sodium Chloride, Dietary | 2008 |
Angiotensin II upregulates LDL receptor-related protein (LRP1) expression in the vascular wall: a new pro-atherogenic mechanism of hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atherosclerosis; Cells, Cultured; Cholesterol Esters; Disease Models, Animal; Humans; Hypertension; Imidazoles; Lactoferrin; Losartan; Low Density Lipoprotein Receptor-Related Protein-1; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Up-Regulation | 2008 |
Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress.
Topics: Angiogenic Proteins; Angiotensin II; Animals; Aorta, Thoracic; Apoptosis; Blotting, Western; Constriction; Disease Models, Animal; Disease Progression; Energy Metabolism; Fibrosis; Heart Failure; Hypertrophy, Left Ventricular; Male; Mechanotransduction, Cellular; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardium; Neovascularization, Physiologic; Phosphorylation; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; Stress, Mechanical; Ventricular Function, Left; Ventricular Remodeling | 2008 |
Angiotensin IV-evoked vasoprotection is conserved in advanced atheroma.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Diet, Atherogenic; Disease Models, Animal; Endothelial Cells; Imidazoles; Male; Mice; Mice, Knockout; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyridines; Receptors, Angiotensin; Superoxides; Up-Regulation | 2008 |
Role of angiotensin II in the enhancement of ammonia production and secretion by the proximal tubule in metabolic acidosis.
Topics: Acidosis; Ammonia; Ammonium Chloride; Angiotensin II; Animals; Disease Models, Animal; Kidney Cortex; Kidney Tubules, Proximal; Losartan; Male; Mice; Perfusion | 2008 |
Renin-angiotensin system component expression in the HL-1 atrial cell line and in a pig model of atrial fibrillation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Fibrillation; Cell Line; Disease Models, Animal; Electric Stimulation; Gene Expression; Myocytes, Cardiac; Renin-Angiotensin System; Swine; Up-Regulation | 2008 |
Integrative control of coronary resistance vessel tone by endothelin and angiotensin II is altered in swine with a recent myocardial infarction.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Hemodynamics; Irbesartan; Myocardial Infarction; Oxygen; Physical Exertion; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Tetrazoles; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation; Ventricular Function, Left; Ventricular Remodeling | 2008 |
Chronic hypoxia increases fetoplacental vascular resistance and vasoconstrictor reactivity in the rat.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetal Growth Retardation; Gestational Age; Hypoxia; Nitroprusside; Placental Circulation; Pregnancy; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
The renin-angiotensin system contributes to renal fibrosis through regulation of fibrocytes.
Topics: Angiotensin II; Animals; Blood Pressure; Bone Marrow; Cells, Cultured; Chemokine CCL21; Collagen Type I; Disease Models, Animal; Fibroblasts; Fibrosis; Hypertension, Renal; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Monocyte Chemoattractant Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1; Ureteral Obstruction; Vasoconstrictor Agents | 2008 |
Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estradiol; Female; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovariectomy; Phenylephrine; Rats; Rats, Sprague-Dawley; Renin; Serotonin; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Inhibition of vascular angiotensin-converting enzyme by telmisartan via the peroxisome proliferator-activated receptor gamma agonistic property in rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Carotid Arteries; Disease Models, Animal; Hypertension; Male; NADPH Oxidases; Peptidyl-Dipeptidase A; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilation; Vasodilator Agents | 2007 |
Gene polymorphism of myospryn (cardiomyopathy-associated 5) is associated with left ventricular wall thickness in patients with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Case-Control Studies; Cells, Cultured; Disease Models, Animal; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Linkage Disequilibrium; Male; Mice; Mice, Inbred C57BL; Middle Aged; Muscle Proteins; Myocytes, Cardiac; Polymorphism, Single Nucleotide; Rats; Rats, Sprague-Dawley; Ultrasonography; Vasoconstrictor Agents | 2007 |
Angiotensin II induces the vascular expression of VEGF and MMP-2 in vivo: preventive effect of red wine polyphenols.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Hypertension; Male; Matrix Metalloproteinase 2; Metalloporphyrins; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Peroxynitrous Acid; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A; Wine | 2008 |
Effect of perindopril on renal medullary blood flow: comparison with other antihypertensive treatments.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Kidney Medulla; Male; Nitric Oxide; Perindopril; Rats | 2008 |
Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Disease Models, Animal; Hypertension; Male; Myocardium; Peptide Fragments; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Time Factors | 2008 |
Aminopeptidase A: could it be a novel target for neurogenic hypertension?
Topics: Angiotensin II; Angiotensin III; Animals; Blood Pressure; Blood-Brain Barrier; Disease Models, Animal; Enzyme Inhibitors; Glutamyl Aminopeptidase; Humans; Hypertension; Rats; Renin-Angiotensin System; Sulfonic Acids | 2008 |
Effects of maternal undernutrition on renal angiotensin II and chymase in hypertensive offspring.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Chymases; Disease Models, Animal; Female; Hypertension; Kidney; Kidney Glomerulus; Malnutrition; Organ Size; Peptidyl-Dipeptidase A; Placenta; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Reference Values | 2008 |
Nitric oxide deficiency and increased adenosine response of afferent arterioles in hydronephrotic mice with hypertension.
Topics: Adenosine; Angiotensin II; Animals; Arterioles; Disease Models, Animal; Enzyme Inhibitors; Hydronephrosis; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Superoxide Dismutase; Superoxide Dismutase-1; Transforming Growth Factors; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Angiotensin II type 1 receptor antagonist improves the prognosis in rats displaying liver cirrhosis induced by a choline-deficient diet.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Choline; Disease Models, Animal; Imidazoles; Lipid Peroxidation; Liver Cirrhosis; Male; Pyridines; Rats; Rats, Inbred F344; Tetrazoles; Vasoconstrictor Agents | 2008 |
Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis.
Topics: Adenoviridae; Angioplasty, Balloon; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Atherosclerosis; Cell Line; Cells, Cultured; Collagen; Diet, Atherogenic; Dietary Fats; Disease Models, Animal; Disease Progression; Genetic Vectors; Humans; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled; Time Factors; Transduction, Genetic; Up-Regulation | 2008 |
The collecting duct is the major source of prorenin in diabetes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Hypertension, Renal; Imidazoles; Immunohistochemistry; Juxtaglomerular Apparatus; Kidney Tubules, Collecting; Microscopy, Fluorescence; Quinacrine; Rats; Rats, Wistar; Renin; Tetrazoles; Trypsin; Vasoconstrictor Agents | 2008 |
Reduced levels of cyclic AMP contribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Angiotensin II; Animals; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Disease Models, Animal; Down-Regulation; Enzyme Activation; Enzyme Activators; Hypertension; Isoproterenol; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides | 2008 |
[An experimental study of expression of angiotension converting enzyme 2 in myocardium and effect of telmisartan treatment in pressure-overloaded rats].
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aortic Coarctation; Benzimidazoles; Benzoates; Disease Models, Animal; Male; Myocardium; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Telmisartan | 2008 |
SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Hypertension; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Niacinamide; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Resveratrol; RNA, Messenger; Sirtuin 1; Sirtuins; Sp1 Transcription Factor; Stilbenes; Time Factors; Transcription, Genetic; Transfection | 2008 |
Angiotensin II increases GABAB receptor expression in nucleus tractus solitarii of rats.
Topics: Action Potentials; Angiotensin II; Animals; Animals, Newborn; Baclofen; Baroreflex; Blood Pressure; Blotting, Western; Cells, Cultured; Disease Models, Animal; GABA Agonists; GABA-B Receptor Agonists; Hypertension; Infusions, Parenteral; Male; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, GABA-A; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solitary Nucleus; Time Factors; Up-Regulation | 2008 |
Collecting duct renin is upregulated in both kidneys of 2-kidney, 1-clip goldblatt hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Hypertension, Renovascular; Immunohistochemistry; Juxtaglomerular Apparatus; Kidney Cortex; Kidney Medulla; Kidney Tubules, Collecting; Male; Rats; Rats, Sprague-Dawley; Renal Artery; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Surgical Instruments; Up-Regulation; Vasoconstrictor Agents | 2008 |
Alpha2-antiplasmin is a critical regulator of angiotensin II-mediated vascular remodeling.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Collagen Type I; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Eye Proteins; Fibrosis; Gelatinases; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nerve Growth Factors; NG-Nitroarginine Methyl Ester; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Serpins; Thoracic Arteries; Tumor Suppressor Protein p53 | 2008 |
Angiotensin II and tumor necrosis factor-alpha synergistically promote monocyte chemoattractant protein-1 expression: roles of NF-kappaB, p38, and reactive oxygen species.
Topics: Angiotensin II; Animals; Antioxidants; Cells, Cultured; Chemokine CCL2; Disease Models, Animal; Femoral Artery; Gene Transfer Techniques; I-kappa B Proteins; Macrophages; Male; Muscle, Smooth, Vascular; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Tunica Intima; Up-Regulation; Vasculitis | 2008 |
Administration of angiotensin II in the paraventricular nucleus protects gastric mucosa from ischemia-reperfusion injury.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Losartan; Male; Paraventricular Hypothalamic Nucleus; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sympathectomy; Time Factors; Vasoconstrictor Agents | 2008 |
Androgen increases AT1a receptor expression in abdominal aortas to promote angiotensin II-induced AAAs in apolipoprotein E-deficient mice.
Topics: Androgens; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Ovariectomy; Receptor, Angiotensin, Type 1; RNA, Messenger; Sex Factors; Time Factors; Up-Regulation | 2008 |
Sex differences in circulating and renal angiotensins of hypertensive mRen(2). Lewis but not normotensive Lewis rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Blood Pressure; Disease Models, Animal; Female; Hypertension; Kidney; Male; Mice; Myocardium; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sex Factors | 2008 |
A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.
Topics: Angiotensin II; Animals; Captopril; Disease Models, Animal; Gene Expression Regulation; Hypertension; Intellectual Disability; Kidney; Mice; Mutation; Phenotype; ras Proteins; Recombination, Genetic; Signal Transduction; Syndrome | 2008 |
Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Antioxidants; Apoptosis; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Fatty Liver; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan | 2008 |
Inhibition of brain proinflammatory cytokine synthesis reduces hypothalamic excitation in rats with ischemia-induced heart failure.
Topics: Action Potentials; Adrenocorticotropic Hormone; Angiotensin II; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Heart Failure; Hypothalamo-Hypophyseal System; Hypothalamus; Inflammation Mediators; Infusions, Parenteral; Interleukin-1beta; Male; Myocardial Ischemia; Norepinephrine; Paraventricular Hypothalamic Nucleus; Pentoxifylline; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Superoxides; Tumor Necrosis Factor-alpha; Ultrasonography | 2008 |
Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Cardiomegaly; Cell Proliferation; Cytoskeleton; Disease Models, Animal; Hypertension; Immunosuppressive Agents; Interferon-gamma; Kidney Diseases; Male; Mice; Mice, Knockout; Mycophenolic Acid; Sodium Chloride, Dietary; T-Lymphocytes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2008 |
AT1 receptor participates in the cardiac hypertrophy induced by resistance training in rats.
Topics: Adaptation, Physiological; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Body Weight; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hemodynamics; Hypertrophy, Left Ventricular; Losartan; Male; Muscle Strength; Myocardium; Physical Exertion; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary; Up-Regulation | 2008 |
Upregulation of interleukin-8/CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Hypertension; Interleukin-8; Losartan; Male; Muscle, Smooth, Vascular; NF-kappa B; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Signal Transduction; Transfection; Up-Regulation; Vasoconstrictor Agents | 2008 |
Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Blood Pressure; Carotid Arteries; Catheterization; Disease Models, Animal; Heart Rate; Hyperplasia; Hypertension; Imidazoles; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tunica Intima | 2008 |
Prolonged increases in vein wall tension increase matrix metalloproteinases and decrease constriction in rat vena cava: Potential implications in varicose veins.
Topics: Angiotensin II; Animals; Biomarkers; Disease Models, Animal; Endothelium, Vascular; Immunoblotting; Immunohistochemistry; Isometric Contraction; Male; Matrix Metalloproteinases; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Factors; Sensitivity and Specificity; Time Factors; Tissue Culture Techniques; Tissue Inhibitor of Metalloproteinase-1; Varicose Veins; Vasoconstriction; Vasodilation; Vena Cava, Inferior; Venous Pressure | 2008 |
Angiotensin-mediated alterations in nephron function in Goldblatt hypertensive rats.
Topics: Administration, Topical; Angiotensin II; Animals; Anti-Inflammatory Agents; Blood Pressure; Chlorides; Disease Models, Animal; Glomerular Filtration Rate; Glucocorticoids; Hypertension, Renal; Kidney Tubules, Distal; Kidney Tubules, Proximal; Nephrons; Rats; Rats, Inbred Strains; Teprotide | 1982 |
Alterations in responses to bradykinin, angiotensin I, and angiotensin II during the induction phase of one-kidney, one-wrapped hypertension and associated arterial disease in rabbits.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Disease Models, Animal; Hypertension, Renal; Hypertension, Renovascular; Male; Nephrectomy; Peptidyl-Dipeptidase A; Perinephritis; Rabbits; Renin | 1980 |
Effect of converting enzyme and angiotensin II inhibitors in chronic one kidney bipolar ligated hypertension.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Hypertension, Renal; Hypertension, Renovascular; Male; Proline; Rats; Renin | 1981 |
Decreased adrenal responsiveness to angiotensin II: a defect present in spontaneously hypertensive rats. A possible model of human essential hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Corticosterone; Disease Models, Animal; Female; Hypertension; Potassium; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Sodium | 1982 |
Delayed reversal of Goldblatt hypertension by angiotensin II infusion in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Carotid Arteries; Disease Models, Animal; Female; Hypertension, Renovascular; Norepinephrine; Rats; Rats, Inbred Strains; Renin | 1984 |
Effect of induced hypertension on experimentally-induced cerebral arterial spasm.
Topics: Angiotensin II; Animals; Basilar Artery; Blood Pressure; Calcium Gluconate; Cats; Disease Models, Animal; Hypertension; Ischemic Attack, Transient; Norepinephrine | 1984 |
Effect of an increased cardiac output on vascular responses to vasoactive agents in two-kidney, one-clip Goldblatt hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Female; Heart Rate; Hemodynamics; Hypertension, Renal; Hypertension, Renovascular; Male; Nitroglycerin; Norepinephrine; Serotonin; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1982 |
Vasodepressor property of the converting enzyme inhibitor captopril (SQ 14 225): the role of factors other than renin-angiotensin blockade in the rat.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Disease Models, Animal; Female; Hypertension; Nephrectomy; Proline; Rats; Renin; Saralasin | 1980 |
HgCl2-induced acute renal failure in the developing rat.
Topics: Acute Kidney Injury; Age Factors; Angiotensin II; Animals; Disease Models, Animal; Female; Male; Mercury; Rats; Renin | 1980 |
Kallikrein-kinin and renin-angiotensin systems in renovascular hypertension in rats.
Topics: Angiotensin II; Animals; Disease Models, Animal; Hypertension, Renal; Hypertension, Renovascular; Kallikreins; Kinins; Male; Rats; Renin | 1980 |
Role of renin-angiotensin system in response to hemorrhage in fetal sheep.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Female; Fetal Blood; Fetal Diseases; Fetus; Heart Rate; Hematocrit; Hemorrhage; Pregnancy; Renin; Saralasin; Sheep | 1981 |
Absence of an antihypertensive effect of 12 hour infusions of an angiotensin antagonist in chronic renal hypertensive rabbits.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Blood Urea Nitrogen; Disease Models, Animal; Hypertension; Hypertension, Renal; Male; Rabbits; Renin; Renin-Angiotensin System; Sodium Chloride | 1981 |
Vincristine reduces damage of the blood-brain barrier induced by high intravascular pressure.
Topics: Angiotensin II; Animals; Blood-Brain Barrier; Brain Diseases; Disease Models, Animal; Hypertension; Male; Rats; Rats, Inbred Strains; Vincristine | 1980 |
One-clip, one-kidney hypertension in rats with hereditary hypothalamic diabetes insipidus.
Topics: Angiotensin II; Animals; Blood Pressure; Diabetes Insipidus; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Renal; Hypertension, Renovascular; Hypothalamic Diseases; Male; Muridae; Saralasin; Vasopressins; Water-Electrolyte Balance | 1982 |
Development of a severe model of early coronary artery ligation-induced dysrhythmias in the anaesthetized rat.
Topics: Androstanols; Angiotensin II; Animals; Arrhythmias, Cardiac; Atropine; Catecholamines; Coronary Vessels; Disease Models, Animal; Disopyramide; Epinephrine; Isoproterenol; Norepinephrine; Phenylephrine; Practolol; Rats; Ventricular Fibrillation | 1981 |
Renal vascular resistance and reactivity in the neurogenic hypertensive rat.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Hemodynamics; Hypertension; Kidney; Male; Norepinephrine; Pressoreceptors; Rats; Vascular Resistance | 1980 |
Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Disease Models, Animal; Endothelins; Endothelium, Vascular; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vascular Resistance | 1994 |
Intrapericardial basic fibroblast growth factor induces myocardial angiogenesis in a rabbit model of chronic ischemia.
Topics: Analysis of Variance; Angiotensin II; Animals; Chronic Disease; Disease Models, Animal; Fibroblast Growth Factor 2; Hypertrophy, Left Ventricular; Infusion Pumps, Implantable; Male; Myocardial Ischemia; Neovascularization, Pathologic; Pericardium; Rabbits; Statistics, Nonparametric; Stimulation, Chemical | 1995 |
SB 203220: a novel angiotensin II receptor antagonist and renoprotective agent.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Kidney Failure, Chronic; Male; Naphthalenes; Nephrectomy; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Thiophenes | 1995 |
Effects of U-97018 on pressor responses to intracerebroventricularly administered angiotensin II in conscious normotensive rats.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Injections, Intravenous; Injections, Intraventricular; Losartan; Male; Pyridazines; Pyridines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Saralasin; Tetrazoles | 1995 |
Prevention by blockade of angiotensin subtype1-receptors of the development of genetic hypertension but not its heritability.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Body Weight; Disease Models, Animal; Diuresis; Female; Genetic Diseases, Inborn; Heart; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Nicotinic Acids; Organ Size; Phenotype; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Tetrazoles | 1995 |
Angiotensin-converting enzyme inhibition in infarct-induced heart failure in rats: bradykinin versus angiotensin II.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Disease Models, Animal; Heart; Heart Failure; Hemodynamics; Imidazoles; Isoquinolines; Losartan; Male; Myocardial Contraction; Myocardial Infarction; Myocardium; Organ Size; Rats; Rats, Wistar; Tetrahydroisoquinolines; Tetrazoles | 1994 |
Sympathetic nerve activity in conscious renal hypertensive rats treated with an angiotensin converting enzyme inhibitor or an angiotensin II antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Heart Rate; Hypertension, Renal; Imidazoles; Lisinopril; Losartan; Male; Nitroprusside; Rats; Rats, Wistar; Renin-Angiotensin System; Splanchnic Nerves; Sympathetic Nervous System; Tetrazoles | 1995 |
Pulmonary edema induced by angiotensin II in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Epinephrine; Imidazoles; Injections, Intravenous; Male; Nitroglycerin; Phentolamine; Pilot Projects; Pulmonary Edema; Pyridines; Rats; Rats, Wistar | 1995 |
Cardiac renin-angiotensin system: role in development of pressure-overload hypertrophy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Stenosis; Blood Pressure; Cardiomegaly; Disease Models, Animal; Heart Failure; Humans; Myocardial Contraction; Rats; Renin-Angiotensin System; Ventricular Function, Left | 1995 |
Potentiation by hypoxia of contractions caused by angiotensin II in dog and monkey cerebral arteries.
Topics: Angiotensin II; Animals; Cerebral Arteries; Constriction, Pathologic; Cyclooxygenase Inhibitors; Dinoprost; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Hypoxia; Macaca; Male; Substance P | 1993 |
Effects of kidney transplantation on the renin-angiotensin systems of the recipients.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Hybridization, Genetic; Hypertension; Kidney; Kidney Transplantation; Male; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 1994 |
Captopril normalises systolic blood pressure in rats with hypertension induced by fetal exposure to maternal low protein diets.
Topics: Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Captopril; Diet, Protein-Restricted; Disease Models, Animal; Female; Hypertension; Lung; Peptidyl-Dipeptidase A; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Renin; Renin-Angiotensin System | 1995 |
Pharmacological properties of KT3-671, a novel nonpeptide angiotensin II receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Binding, Competitive; Blood Pressure; Bradykinin; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hypertension; Imidazoles; In Vitro Techniques; Liver; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Artery; Tetrazoles | 1995 |
Different responses of renal blood flow and sympathetic nerve activity to captopril and nicardipine in conscious renal hypertensive rabbits.
Topics: Analysis of Variance; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Disease Models, Animal; Female; Heart Rate; Hypertension, Renal; Kidney; Nicardipine; Norepinephrine; Rabbits; Regional Blood Flow; Renal Circulation; Sympathetic Nervous System; Vascular Resistance; Vasodilation | 1995 |
Further evidence for the interactions between angiotensin II and GABAergic transmission in pentylenetetrazol kindling seizures in mice.
Topics: Angiotensin II; Animals; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Phenylurea Compounds; Receptors, GABA; Seizures | 1995 |
Role of angiotensin II in cerebrovascular and renal damage in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Desoxycorticosterone; Disease Models, Animal; Enalapril; Hypertension; Kidney; Male; Rats; Rats, Wistar; Receptors, GABA-A; Renin-Angiotensin System; Sodium Chloride; Tetrazoles | 1995 |
Pharmacological profile of ME3221, a novel angiotensin II receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Bradykinin; Callithrix; Disease Models, Animal; Drug Evaluation; Female; Femoral Artery; Heart Rate; Hypertension, Renal; Imidazoles; Losartan; Male; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Species Specificity; Tetrazoles | 1995 |
Renal, endocrine and vascular effects of atrial natriuretic peptide in a novel vasopressin-deficient genetically hypertensive strain of rat.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Animal; Endocrine Glands; Heart Rate; Hypertension; Kidney; Male; Rats; Rats, Inbred Strains; Sodium; Vasopressins; Water | 1995 |
Role of polyamines in hypertension induced by angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Cardiomegaly; Disease Models, Animal; Heart Ventricles; Hypertension; Liver; Male; Mesenteric Arteries; Myocardium; Polyamines; Putrescine; Rats; Rats, Inbred WKY; Spermidine; Spermine | 1995 |
An angiotensin II receptor antagonist reduces myocardial damage in an animal model of myocarditis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; Cardiovirus Infections; Disease Models, Animal; Encephalomyocarditis virus; Heart; Male; Mice; Mice, Inbred DBA; Myocarditis; Myocardium; Organ Size; Survival Analysis; Tetrazoles; Virus Replication | 1994 |
Alterations in glomerular dynamics in congenital, unilateral hydronephrosis.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Fatty Acids, Unsaturated; Glomerular Filtration Rate; Hydrazines; Hydronephrosis; Imidazoles; Kidney Glomerulus; Losartan; Male; Rats; Rats, Inbred Strains; Rats, Wistar; Saralasin; Tetrazoles; Thromboxane A2 | 1994 |
Decreased density of endothelin binding sites in adrenal glands but not in aorta, of long term infarcted rats.
Topics: Adrenal Glands; Angiotensin II; Animals; Aorta, Thoracic; Binding Sites; Disease Models, Animal; Endothelins; Male; Myocardial Ischemia; Rats; Time Factors | 1994 |
Discrepancy between plasma and lung angiotensin-converting enzyme activity in experimental congestive heart failure. A novel aspect of endothelium dysfunction.
Topics: Analysis of Variance; Angiotensin II; Animals; Atrial Natriuretic Factor; Cell Membrane; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Heart; Heart Failure; Kidney; Lung; Male; Myocardial Infarction; Organ Size; Peptidyl-Dipeptidase A; Pleural Effusion; Rats; Rats, Wistar; Renin; RNA, Messenger | 1994 |
Learning from rats to reduce people's desire for alcohol.
Topics: Alcoholism; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Rats; Thirst | 1993 |
Comparison of the effects of EXP3174, an angiotensin II antagonist and enalaprilat on myocardial infarct size in anaesthetized dogs.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Disease Models, Animal; Dogs; Enalaprilat; Female; Furosemide; Heart Rate; Imidazoles; Injections, Intravenous; Losartan; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Renin-Angiotensin System; Tetrazoles | 1993 |
Regulation of intrarenal and circulating renin-angiotensin systems in severe heart failure in the rat.
Topics: Angiotensin II; Angiotensinogen; Animals; Blotting, Northern; Disease Models, Animal; Heart Failure; Kidney; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 1993 |
Effects of endothelin and angiotensin II on renal hemodynamics in experimental mesangial proliferative nephritis.
Topics: Angiotensin II; Animals; Antilymphocyte Serum; Disease Models, Animal; Endothelins; Glomerular Mesangium; Glomerulonephritis, Membranoproliferative; Hypertension, Renal; Rats; Rats, Wistar; Renal Circulation | 1993 |
TCV-116, a novel angiotensin II receptor antagonist, prevents intimal thickening and impairment of vascular function after carotid injury in rats.
Topics: Acetylcholine; Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Carotid Arteries; Carotid Artery Diseases; Catheterization; Cell Division; Disease Models, Animal; DNA; Endothelium, Vascular; Male; Microscopy, Electron, Scanning; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Tetrazoles; Tunica Intima | 1993 |
Increased adrenal renin in transgenic hypertensive rats, TGR(mREN2)27, and its regulation by cAMP, angiotensin II, and calcium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Glands; Angiotensin II; Animals; Animals, Genetically Modified; Calcimycin; Calcium; Cyclic AMP; Disease Models, Animal; Enzyme Precursors; Female; Hypertension; Male; Mice; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1993 |
Hypertensive rats produced by in vivo introduction of the human renin gene.
Topics: Angiotensin II; Animals; Disease Models, Animal; Gene Transfer Techniques; Histidine; Humans; Hypertension; Male; Morpholines; Rats; Rats, Wistar; Renin | 1993 |
Antihypertensive activity of ABBOTT-81282, a nonpeptide angiotensin II antagonist, in the renal hypertensive rat.
Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Consciousness; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hypertension, Renovascular; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 1993 |
Action of carbon dioxide on hypoxic pulmonary vasoconstriction in the rat lung: evidence against specific endothelium-derived relaxing factor-mediated vasodilation.
Topics: Angiotensin II; Animals; Arginine; Blood Gas Analysis; Carbon Dioxide; Constriction, Pathologic; Disease Models, Animal; Drug Evaluation, Preclinical; Hypercapnia; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Pulmonary Wedge Pressure; Random Allocation; Rats; Rats, Wistar; Respiration, Artificial; Vascular Resistance | 1993 |
Functional roles of brain AT1 and AT2 receptors in the central angiotensin II pressor response in conscious young spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Brain; Disease Models, Animal; Heart Rate; Hypertension; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Vasopressins | 1993 |
Central and peripheral vasopressin interact differently with sympathetic nervous system and renin-angiotensin system in renal hypertensive rabbits.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Clonidine; Disease Models, Animal; Female; Hypertension, Renovascular; Kidney; Nicardipine; Norepinephrine; Rabbits; Renin-Angiotensin System; Sympathetic Nervous System | 1993 |
[Hormonal contribution to short-term variability of blood pressure in a renovascular hypertension model].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Disease Models, Animal; Heart Rate; Hypertension, Renovascular; Imidazoles; Kallikrein-Kinin System; Losartan; Male; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Signal Processing, Computer-Assisted; Tetrazoles | 1995 |
Effects of endothelin-1 on the contractility of cardiomyocytes from the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelins; Heart Ventricles; Hypertension; Isotonic Contraction; Myocardial Contraction; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents | 1995 |
Effects of subtype-selective and balanced angiotensin II receptor antagonists in a porcine coronary artery model of vascular restenosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Coronary Disease; Coronary Vessels; Disease Models, Animal; Imidazoles; Rats; Recurrence; Sulfonamides; Swine; Tetrazoles | 1996 |
Adverse influence of systemic vascular stiffening on cardiac dysfunction and adaptation to acute coronary occlusion.
Topics: Acute Disease; Angiotensin II; Animals; Blood Vessels; Cardiac Output; Compliance; Coronary Circulation; Disease Models, Animal; Dogs; Female; Hemodynamics; Hypertension; Male; Myocardial Infarction; Myocardial Ischemia; Vascular Resistance | 1996 |
Role of aldosterone in the remnant kidney model in the rat.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Body Weight; Disease Models, Animal; Enalapril; Imidazoles; Kidney; Kidney Diseases; Losartan; Male; Mineralocorticoid Receptor Antagonists; Nephrectomy; Organ Size; Rats; Rats, Sprague-Dawley; Spironolactone; Tetrazoles | 1996 |
The role of the renin-angiotensin system in cisplatin nephrotoxicity.
Topics: Angiotensin II; Animals; Antineoplastic Agents; Biphenyl Compounds; Blood Urea Nitrogen; Cisplatin; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Injections, Intraperitoneal; Kidney; Kidney Function Tests; Losartan; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles | 1995 |
Glomerular angiotensin II receptors in gentamicin-induced renal failure in the rat.
Topics: Acute Kidney Injury; Analysis of Variance; Angiotensin II; Animals; Anti-Bacterial Agents; Creatinine; Disease Models, Animal; Female; Gentamicins; Kidney Glomerulus; Rats; Rats, Wistar; Receptors, Angiotensin | 1995 |
Beneficial effect of amiloride, A Na(+)-H+ exchange blocker, in a murine model of dilated cardiomyopathy.
Topics: Amiloride; Angiotensin II; Animals; Body Weight; Cardiomyopathy, Dilated; Disease Models, Animal; Diuretics; Female; Furosemide; Heart; Mice; Mice, Inbred DBA; Myocardium; Organ Size; Sodium-Hydrogen Exchangers | 1996 |
Modification of aortic contractility in the cardiomyopathic hamster.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Potassium Chloride; Protein Kinase C; Signal Transduction; Sodium Fluoride; Vasoconstrictor Agents | 1996 |
Comparison between chronic converting enzyme inhibition and AT1 blockade in mRen2 transgenic rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Isoquinolines; Losartan; Male; Natriuresis; Quinapril; Rats; Tetrahydroisoquinolines; Tetrazoles | 1996 |
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat is prevented by tolrestat.
Topics: Aldehyde Reductase; Angiotensin II; Animals; Arterioles; Blood Pressure; Cohort Studies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Galactitol; Galactose; Image Processing, Computer-Assisted; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Naphthalenes; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 1996 |
Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Crosses, Genetic; Disease Models, Animal; Female; Humans; Hypertension; Kidney Glomerulus; Male; Mice; Mice, Transgenic; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1996 |
Perindopril treatment prevents the loss of endothelial nitric oxide function and development of neo-intima in rabbits.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Carotid Arteries; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; In Vitro Techniques; Indoles; Nitric Oxide; Peptidyl-Dipeptidase A; Perindopril; Rabbits; Serotonin; Vasoconstriction; Vasodilation | 1996 |
Mouse model for pregnancy problem?
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Crosses, Genetic; Disease Models, Animal; Female; Humans; Hypertension; Male; Mice; Mice, Transgenic; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1996 |
Effects of long-term treatment with trandolapril on augmented vasoconstriction in rats with chronic heart failure.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Coronary Vessels; Culture Techniques; Disease Models, Animal; Drug Interactions; Heart Failure; Hemodynamics; Indoles; Male; Muscle, Smooth, Vascular; Norepinephrine; Prostaglandins F; Rats; Rats, Wistar; Reference Values; Vasoconstriction; Vasoconstrictor Agents | 1996 |
Renal response to blood pressure elevation in normal and glomerulonephritic rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Glomerulonephritis; Hypertension, Renovascular; Kidney; Kidney Glomerulus; Male; Rats; Rats, Wistar; Regression Analysis | 1996 |
The renin-angiotensin system and renal function in transgenic (mRen2)27 rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Disease Models, Animal; Hypertension, Renal; Kidney; Mice; Natriuresis; Pressure; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 1996 |
Diastolic properties in canine hypertensive left ventricular hypertrophy: effects of angiotensin converting enzyme inhibition and angiotensin II type-1 receptor blockade.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Diastole; Disease Models, Animal; Dogs; Enalaprilat; Hypertension, Renal; Hypertrophy, Left Ventricular; Imidazoles; Receptors, Angiotensin; Tetrazoles; Ventricular Function, Left | 1997 |
Effects of enalapril, losartan, and verapamil on blood pressure and glucose metabolism in the Cohen-Rosenthal diabetic hypertensive rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Disease Models, Animal; Enalapril; Glucose; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred Strains; Tetrazoles; Verapamil | 1997 |
Role of the renal kallikrein-kinin system in the development of hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Bradykinin; Disease Models, Animal; Hypertension; Infusions, Intra-Arterial; Injections, Subcutaneous; Kallikrein-Kinin System; Kidney Tubules; Kininogens; Lactones; Molecular Weight; Norepinephrine; Rats; Rats, Inbred BN; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium Chloride; Sodium, Dietary | 1997 |
Angiotensin receptor antagonism and angiotensin converting enzyme inhibition improve diastolic dysfunction and Ca(2+)-ATPase expression in the sarcoplasmic reticulum in hypertensive cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blotting, Northern; Blotting, Western; Calcium-Transporting ATPases; Captopril; Cardiomyopathy, Hypertrophic; Diastole; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Mice; Mice, Transgenic; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sarcoplasmic Reticulum; Tetrazoles | 1997 |
Role of the angiotensin II type 1 receptor in preconditioning against infarction.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Rabbits; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 1997 |
Actions of angiotensin and lisinopril on thalamic somatosensory neurons in normotensive, non-transgenic and hypertensive, transgenic rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Disease Models, Animal; Electroencephalography; Hypertension; Imidazoles; Lisinopril; Losartan; Male; Neurons, Afferent; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thalamus; Vasoconstrictor Agents | 1997 |
Interaction of angiotensin II and TGF-beta 1 in the rat remnant kidney.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Culture Techniques; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Kidney; Kidney Glomerulus; Losartan; Male; Nephrectomy; Organ Size; Rats; Rats, Sprague-Dawley; Reference Values; RNA; Transforming Growth Factor beta | 1997 |
Effect of continuous regional vasoactive agent infusion on liver metastasis blood flow.
Topics: Angiotensin II; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Endothelin-1; Infusions, Intra-Arterial; Laser-Doppler Flowmetry; Liver Circulation; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 1997 |
Pharmacokinetic-pharmacodynamic relations of losartan and EXP3174 in a porcine animal model.
Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Area Under Curve; Blood Pressure; Disease Models, Animal; Half-Life; Hypertension; Imidazoles; Infusions, Intravenous; Losartan; Receptors, Angiotensin; Swine; Tetrazoles | 1997 |
Pharmacologic profiles of KRH-594, a novel nonpeptide angiotensin II-receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Cattle; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Liver; Losartan; Male; Rabbits; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles; Thiadiazoles | 1997 |
[Bosentan attenuates the hypertensive effect of angiotensin II in rats].
Topics: Angiotensin II; Animals; Blood Pressure; Bosentan; Disease Models, Animal; Drug Interactions; Endothelin Receptor Antagonists; Endothelins; Hemodynamics; Hypertension; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Sulfonamides | 1997 |
The role of endothelin in radiocontrast nephropathy.
Topics: Angiotensin II; Animals; Blood Urea Nitrogen; Contrast Media; Diatrizoate; Diatrizoate Meglumine; Disease Models, Animal; Drug Combinations; Endothelins; Infusions, Intravenous; Iodine; Kidney; Kidney Diseases; Male; Nephrectomy; Radioimmunoassay; Radioisotopes; Random Allocation; Rats; Rats, Wistar; Reference Values | 1997 |
Effect of the novel angiotensin II type 1 receptor antagonist L-158,809 on acute infarct expansion and acute anterior myocardial infarction in the dog.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Disease Models, Animal; Dogs; Echocardiography; Imidazoles; Myocardial Infarction; Random Allocation; Tetrazoles; Ventricular Function, Left | 1998 |
Effect of ecadotril, a neutral endopeptidase inhibitor, on myocardial hypertrophy in the rat aortic insufficiency model.
Topics: Angiotensin II; Animals; Aortic Diseases; Blood Pressure; Cardiomegaly; Disease Models, Animal; Guanosine Monophosphate; Male; Protease Inhibitors; Rats; Rats, Wistar; Thiorphan | 1998 |
Mesenteric and skeletal muscle microvascular responsiveness in subacute sepsis.
Topics: Angiotensin II; Animals; Blood Vessels; Disease Models, Animal; Hemodynamics; Male; Microcirculation; Microscopy, Video; Muscle, Skeletal; Peritonitis; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Sepsis; Splanchnic Circulation; Staurosporine; Vascular Resistance | 1998 |
Endogenous angiotensin II and cell hypertrophy in vascular smooth muscle cultures from hypertensive Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cell Division; Cell Size; Cells, Cultured; Disease Models, Animal; Femoral Artery; Gene Expression Regulation; Genes, fos; Genes, jun; Hypertension; Hypertrophy; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Renin; Tunica Media | 1998 |
Angiotensin II and endothelin-1 receptor antagonists have cumulative hypotensive effects in canine Page hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bosentan; Disease Models, Animal; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Renovascular; Infusions, Intravenous; Losartan; Radioimmunoassay; Receptor, Endothelin A; Sulfonamides; Vascular Resistance | 1998 |
Nitric oxide release as an essential mitigating step in tubuloglomerular feedback: observations during intrarenal nitric oxide clamp.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Enalapril; Enzyme Inhibitors; Feedback; Glomerular Filtration Rate; Kidney Glomerulus; Kidney Tubules; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pressoreceptors; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation | 1998 |
Differences in tissue angiotensin II-forming pathways by species and organs in vitro.
Topics: Aged; Angiotensin II; Animals; Aorta; Chymases; Disease Models, Animal; Female; Humans; Lung; Male; Mammals; Middle Aged; Myocardium; Peptidyl-Dipeptidase A; Serine Endopeptidases; Species Specificity | 1998 |
[Effect of chronic bradykinin infusion on angiotensin II hypertension in rats].
Topics: Angiotensin II; Animals; Bradykinin; Disease Models, Animal; Hypertension; Hypertrophy, Left Ventricular; Male; Rats; Rats, Sprague-Dawley | 1998 |
Pulmonary arterioles from rats with congenital diaphragmatic hernias are hypoplastic but not hyperresponsive.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Angiotensin II; Animals; Arterioles; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetus; Herbicides; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Phenyl Ethers; Phenylephrine; Pregnancy; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Serotonin; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Basement Membrane; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; Female; Glomerulonephritis; Kidney Glomerulus; Macrophages; Male; Mice; Mice, Knockout; Monocytes; Proteinuria; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, IgG; Tetrazoles | 1998 |
Combined effects of angiotensin converting enzyme inhibition and angiotensin II receptor antagonism in conscious pigs with congestive heart failure.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalaprilat; Female; Heart Failure; Hemodynamics; Imidazoles; Male; Swine; Tetrazoles | 1998 |
Response of EP and cochlear blood flow to angiotensin II during hypoxic condition.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Cochlea; Disease Models, Animal; Glycolysis; Guinea Pigs; Hypoxia; Oxygen Consumption; Stria Vascularis; Vasoconstrictor Agents | 1998 |
AT1 angiotensin II receptor inhibition in pacing-induced heart failure: effects on left ventricular performance and regional blood flow patterns.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Cardiac Pacing, Artificial; Coronary Vessels; Disease Models, Animal; Exercise Test; Heart Failure; Hemodynamics; Male; Regional Blood Flow; Swine; Tetrazoles; Valine; Valsartan; Vascular Resistance; Ventricular Function, Left | 1998 |
Angiotensin AT1 receptor inhibition, angiotensin-converting enzyme inhibition, and combination therapy with developing heart failure: cellular mechanisms of action.
Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Cardiac Pacing, Artificial; Disease Models, Animal; Drug Therapy, Combination; Evaluation Studies as Topic; Heart Failure; Myocardium; Random Allocation; Swine; Ventricular Function, Left | 1998 |
Blocking angiotensin II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Cilazapril; Collagen; Disease Models, Animal; Glomerulonephritis, Membranoproliferative; Hydralazine; Kidney Failure, Chronic; Male; Proteinuria; Rats; Rats, Wistar; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta | 1999 |
Renal function in high-output heart failure in rats: role of endogenous natriuretic peptides.
Topics: Analysis of Variance; Angiotensin II; Animals; Atrial Natriuretic Factor; Cyclic GMP; Disease Models, Animal; Glomerular Filtration Rate; Heart Failure; Kidney Function Tests; Male; Polysaccharides; Rats; Rats, Wistar; Reference Values; Renal Circulation; Statistics, Nonparametric; Urodynamics | 1999 |
Chronic bradykinin infusion and receptor blockade in angiotensin II hypertension in rats.
Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Disease Models, Animal; Hemodynamics; Hypertension; Kidney; Male; Organ Size; Potassium; Rats; Rats, Sprague-Dawley | 1999 |
[Modelling of myocardial hypertrophy in vitro for solving problems of medicinal correction].
Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Blood Physiological Phenomena; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Fibroblasts; Models, Biological; Norepinephrine; Protein Biosynthesis; Rats; Stimulation, Chemical; Surface Properties | 1998 |
Vascular alterations during the development and progression of experimental heart failure.
Topics: Angiotensin II; Animals; Cricetinae; Disease Models, Animal; Disease Progression; Heart Failure; Male; Mesocricetus; Norepinephrine; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Protective effects of ischemic preconditioning on lung ischemia reperfusion injury: an in-vivo rabbit study.
Topics: Angiotensin II; Animals; Blood Gas Analysis; Disease Models, Animal; Follow-Up Studies; Ischemic Preconditioning; Lung; Lung Diseases; Male; Malondialdehyde; Rabbits; Random Allocation; Reperfusion Injury; Superoxide Dismutase; Treatment Outcome | 1999 |
The renal lesions that develop in neonatal mice during angiotensin inhibition mimic obstructive nephropathy.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Newborn; Apoptosis; Cell Division; Disease Models, Animal; Epidermal Growth Factor; Gene Expression Regulation, Developmental; In Situ Hybridization; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Kidney Diseases; Kidney Medulla; Kidney Pelvis; Macrophages; Mice; Mice, Knockout; Muscle, Smooth; Peptidyl-Dipeptidase A; Platelet-Derived Growth Factor; Pressure; RNA, Messenger; Transforming Growth Factor beta; Ureter; Ureteral Obstruction | 1999 |
The effects of short-term nifedipine treatment on responsiveness of aortic rings of cadmium-hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cadmium Chloride; Calcium Channel Blockers; Disease Models, Animal; Endothelin-1; Follow-Up Studies; Hypertension; Male; Nifedipine; Norepinephrine; Random Allocation; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Evidence of a possible role of altered angiotensin function in the treatment, but not etiology, of depression.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Binding Sites; Cell Culture Techniques; Depression, Postpartum; Desipramine; Disease Models, Animal; Female; Fluoxetine; Humans; Losartan; Male; Mice; Receptors, Angiotensin; Tranylcypromine | 1999 |
[Combined blockade of the renin-angiotensin system].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Humans; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System | 1999 |
Effects of a lipoxygenase inhibitor, panaxynol, on vascular contraction induced by angiotensin II.
Topics: Alkynes; Angiotensin II; Animals; Blood Pressure; Cricetinae; Disease Models, Animal; Diynes; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Fatty Alcohols; Hypertension; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Vasoconstriction | 1999 |
EXP3174, the AII antagonist human metabolite of losartan, but not losartan nor the angiotensin-converting enzyme inhibitor captopril, prevents the development of lethal ischemic ventricular arrhythmias in a canine model of recent myocardial infarction.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Captopril; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Heart Ventricles; Humans; Imidazoles; Losartan; Male; Myocardial Infarction; Myocardial Ischemia; Tetrazoles; Time Factors | 1999 |
Sudden pressure elevation can trigger acute muscle cell death of the heart and aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Apoptosis; Blood Pressure; Cell Survival; Cells, Cultured; Disease Models, Animal; Drug Interactions; Hypertension; In Situ Nick-End Labeling; Injections, Intravenous; Male; Muscle, Smooth, Vascular; Myocardium; Necrosis; Rabbits; Reference Values; Statistics, Nonparametric; Viper Venoms | 1999 |
Angiotensin II atherogenicity in apolipoprotein E deficient mice is associated with increased cellular cholesterol biosynthesis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Apolipoproteins E; Arteriosclerosis; Cell Line; Cholesterol; Disease Models, Animal; DNA Primers; Gene Expression; Humans; Hydroxymethylglutaryl CoA Reductases; Injections, Intraperitoneal; Macrophages, Peritoneal; Mice; Monocytes; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Vasoconstrictor Agents | 1999 |
Increased bradykinin levels accompany the hemodynamic response to acute inhibition of angiotensin-converting enzyme in dogs with heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Cardiac Output; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Enalaprilat; Heart Failure; Indoles; Norepinephrine; Peptide Fragments; Ventricular Function, Left | 1999 |
Angiotensin II receptor content within the circumventricular organs increases after experimental hydrocephalus in rats.
Topics: Angiotensin II; Animals; Autoradiography; Cerebral Ventricles; Disease Models, Animal; Hydrocephalus; Male; Rats; Receptors, Angiotensin | 1999 |
Nitric oxide affects angiotensin II pressor response: possible mechanism of attenuated pressor response during pregnancy and etiology of pregnancy-induced hypertension.
Topics: Angiotensin II; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Female; Hypertension; Injections, Intraperitoneal; Nitric Oxide; omega-N-Methylarginine; Pregnancy; Pregnancy Complications, Cardiovascular; Pressoreceptors; Probability; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Software; Vasoconstrictor Agents | 2000 |
Effect of angiotensin II on liposome uptake by the rat brain in vivo.
Topics: Angiotensin II; Animals; Area Under Curve; Blood-Brain Barrier; Brain; Disease Models, Animal; Drug Carriers; Hypertension; Liposomes; Rats | 1999 |
Comparative effects of pretreatment with captopril and losartan on cardiovascular protection in a rat model of ischemia-reperfusion.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Captopril; Disease Models, Animal; Electrocardiography; Female; Heart Rate; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Sprague-Dawley; Renin; Treatment Outcome; Ventricular Fibrillation | 2000 |
Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cell Line, Transformed; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glomerular Filtration Rate; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Hydralazine; Hypertension; Immunohistochemistry; Kidney Tubules, Proximal; Losartan; Norepinephrine; Oxidative Stress; Proteinuria; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Effect of maximal reduction of angiotensin in renal fibrosis: bad news-good news from a pediatric mouse.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Disease Models, Animal; Fibrosis; Kidney Diseases; Mice; Plasminogen Activator Inhibitor 1; Renin-Angiotensin System; Transforming Growth Factor beta; Ureteral Obstruction | 2000 |
Association between the molecular pathobiology of essential hypertension and thrombotic diseases.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Coronary Disease; Disease Models, Animal; Humans; Hypertension; Mice; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Thromboplastin; Thrombosis | 2000 |
Angiotensin II induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Blotting, Northern; Desoxycorticosterone; Disease Models, Animal; Enzyme Activation; Epithelial Cells; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hypertension, Renal; In Vitro Techniques; Kidney Failure, Chronic; Kidney Tubules; LLC-PK1 Cells; Male; Nephrectomy; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; RNA, Messenger; Swine; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents | 2000 |
Disparate responses of tumour vessels to angiotensin II: tumour volume-dependent effects on perfusion and oxygenation.
Topics: Angiotensin II; Animals; Disease Models, Animal; Laser-Doppler Flowmetry; Male; Neoplasms, Experimental; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasoconstrictor Agents | 2000 |
Modulation of apoptotic and inflammatory genes by bioflavonoids and angiotensin II inhibition in ureteral obstruction.
Topics: Angiotensin II; Animals; Apoptosis; Chemokines; Curcumin; Disease Models, Animal; Flavonoids; Gene Expression; Kidney Diseases; Male; Nephritis; Quercetin; Rats; Rats, Sprague-Dawley; Ureteral Obstruction | 2000 |
Inhibited expression of insulin-like growth factor I mRNA and attenuated cardiac hypertrophy in volume overloaded hearts treated with difluoromethylornithine.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Eflornithine; Gene Expression Regulation; Hypertrophy, Right Ventricular; Insulin-Like Growth Factor I; Male; Organ Size; Ornithine Decarboxylase Inhibitors; Rats; Rats, Wistar; RNA, Messenger | 1998 |
Early sequence of cardiac adaptations and growth factor formation in pressure- and volume-overload hypertrophy.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Blood Pressure; Cardiac Volume; Cardiomegaly; Disease Models, Animal; Echocardiography; Endothelin-1; Female; Hemodynamics; In Situ Hybridization; Insulin-Like Growth Factor I; Male; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine | 2000 |
Induction of angiotensin II subtype 2 receptor-mediated blood pressure regulation in synthetic diet-fed rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Captopril; Cardiac Glycosides; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Gene Expression; Imidazoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Weight Gain | 2000 |
Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cell Division; Cholesterol; Creatinine; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Kidney; Kidney Failure, Chronic; Leukocytes; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organ Size; Phosphorylation; Plasminogen Activators; Pyridines; Rats; Rats, Sprague-Dawley; Renin; Thromboplastin; Transcription Factor AP-1; Urea; Vascular Cell Adhesion Molecule-1; Vasoconstrictor Agents | 2000 |
Osteopontin expression in progressive renal injury in remnant kidney: role of angiotensin II.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Disease Models, Animal; Gene Expression; In Situ Hybridization; Kidney; Macrophages; Male; Nephrectomy; Nephritis, Interstitial; Osteopontin; Ramipril; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Tetrazoles; Valine; Valsartan | 2000 |
Beneficial renal and hemodynamic effects of omapatrilat in mild and severe heart failure.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output; Cardiovascular Agents; Cross-Over Studies; Cyclic GMP; Disease Models, Animal; Glomerular Filtration Rate; Heart Failure; Hemodynamics; Injections, Intravenous; Kidney; Natriuretic Peptide, Brain; Pyridines; Renin; Sheep; Sodium; Thiazepines | 2000 |
Effect of angiotensin II blockade on renal injury in mineralocorticoid-salt hypertension.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Disease Models, Animal; Enalapril; Hypertension, Renal; Kidney; Kidney Function Tests; Losartan; Male; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Renal Insufficiency; Sodium Chloride | 2000 |
Hypothesis regarding the pathophysiological role of alternative pathways of angiotensin II formation in atherosclerosis.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Chymases; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Mesocricetus; Renin; Renin-Angiotensin System; Serine Endopeptidases | 2000 |
Renovascular hypertension: structural changes in the renal vasculature.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension, Renovascular; Kidney; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renal Artery Obstruction; Vascular Resistance | 2000 |
Angiotensin II infused intrarenally causes preglomerular vascular changes and hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hypertension; Infusions, Intra-Arterial; Kidney; Losartan; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Renal Artery; Renal Circulation; Vascular Resistance | 2000 |
Interleukin-1beta and neurogenic control of blood pressure in normal rats and rats with chronic renal failure.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Antibodies; Blood Pressure; Creatinine; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Hypothalamus, Posterior; Interleukin-1; Kidney Failure, Chronic; Male; Nephrectomy; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Phentolamine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathetic Nervous System; Vasoconstrictor Agents | 2000 |
In vivo activation of rat aortic platelet-derived growth factor and epidermal growth factor receptors by angiotensin II and hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Enalapril; ErbB Receptors; Hypertension; Infusions, Intravenous; Male; Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Perindopril; Phosphorylation; Rats; Rats, Inbred SHR; Receptors, Platelet-Derived Growth Factor | 2000 |
New method for imaging innervation of the renal preglomerular vasculature. Alterations in hypertensive rats.
Topics: Adrenergic Fibers; Angiotensin II; Animals; Arteries; Disease Models, Animal; Hypertension; Immunohistochemistry; Kidney; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Synaptophysin | 2000 |
Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction--effects of AT(1) and AT(2) receptor antagonists and ACE inhibitor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium-Binding Proteins; Calpain; Disease Models, Animal; Gene Expression Regulation; Heart; Heart Rate; Imidazoles; Male; Myocardial Infarction; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transcription, Genetic; Valine; Valsartan | 2001 |
Insulin-like growth factor-binding protein-3 induces fetalization in neonatal rat cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Coronary Vessels; Disease Models, Animal; Disease Progression; Endothelin-1; Gene Expression Profiling; Gene Expression Regulation; Heart Ventricles; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Myocardial Infarction; Myocardium; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Oligonucleotide Array Sequence Analysis; Rats; RNA, Messenger; Transforming Growth Factor beta; Troponin I | 2000 |
Genetic variation in angiotensin-converting enzyme does not prevent development of cardiac hypertrophy or upregulation of angiotensin II in response to aortocaval fistula.
Topics: Angiotensin II; Animals; Aorta; Arteriovenous Fistula; Cardiomegaly; Chymases; Disease Models, Animal; Genetic Variation; Male; Mice; Mice, Knockout; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Serine Endopeptidases; Up-Regulation; Vena Cava, Inferior; Ventricular Dysfunction, Left | 2001 |
Antiangiogenic effect of KR31372 in rat sponge implant model.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Benzopyrans; Disease Models, Animal; Drug Interactions; Endothelial Growth Factors; Glyburide; Humans; Hypoglycemic Agents; Lymphokines; Models, Biological; Neovascularization, Pathologic; Prostheses and Implants; Rats; Surgical Sponges; Technetium; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Control of renin secretion from adrenal gland in transgenic Ren-2 and normal rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Disease Models, Animal; Enalapril; Enzyme Precursors; Female; Ganglionic Blockers; Gene Dosage; Hexamethonium; Histamine; Hypertension; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renin; Vasoconstrictor Agents | 2001 |
Antisense inhibition of thyrotropin-releasing hormone reduces arterial blood pressure in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cerebral Ventricles; Disease Models, Animal; DNA, Antisense; Hypertension; Male; Oligonucleotides, Antisense; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Thyroid Hormones; Thyrotropin-Releasing Hormone | 2001 |
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
Topics: Acetylcholine; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Dinoprost; Disease Models, Animal; Endothelium, Vascular; F2-Isoprostanes; Humans; Hypertension; Ketone Oxidoreductases; Male; Nitrates; Nitrites; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Renin; Superoxide Dismutase; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilation | 2001 |
Workshop: mechanisms and cardiovascular damage in hypertension.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Cardiovascular System; Cell Nucleus; Disease Models, Animal; Hypertension; I-kappa B Kinase; Inflammation; Models, Chemical; Muscle, Smooth, Vascular; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Renin-Angiotensin System; Signal Transduction | 2001 |
The role of ANG II and endothelin-1 in exercise-induced diastolic dysfunction in heart failure.
Topics: Acetamides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Function, Left; Diastole; Disease Models, Animal; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Losartan; Nitroprusside; Physical Exertion; Reference Values; Vasodilation; Ventricular Function, Left | 2001 |
AT1 receptor antagonism enhances angiotensin-II-facilitated carrageenan-induced paw edema.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carrageenan; Disease Models, Animal; Drug Synergism; Edema; Extremities; Inflammation; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Vasoconstrictor Agents | 2000 |
Enhancement of angiotensinogen expression in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensins; Animals; Blood Pressure; Blotting, Western; Body Weight; Diet; Disease Models, Animal; Hypertension; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sodium, Dietary | 2001 |
Combined effects of AT(1) and ET(A) receptor antagonists, candesartan, and A-127722 in DOCA-salt hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Desoxycorticosterone; Disease Models, Animal; Drug Therapy, Combination; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Natriuresis; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2000 |
Lead-cadmium interaction effect on the responsiveness of rat mesenteric vessels to norepinephrine and angiotensin II.
Topics: Analysis of Variance; Angiotensin II; Animals; Cadmium Poisoning; Calcium; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Ketoprofen; Lead Poisoning; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Papaverine; Potassium Chloride; Rats; Rats, Inbred BUF; Receptors, Angiotensin; Vasoconstriction; Vasoconstrictor Agents; Verapamil | 2001 |
Mycophenolate mofetil prevents salt-sensitive hypertension resulting from angiotensin II exposure.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Cell Division; Creatinine; Disease Models, Animal; Fibronectins; Hypertension, Renal; Kidney; Leukocytes, Mononuclear; Lipid Peroxidation; Male; Malondialdehyde; Mycophenolic Acid; Osteopontin; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sialoglycoproteins; Superoxides; Vasoconstrictor Agents | 2001 |
Biomechanical strain induces class a scavenger receptor expression in human monocyte/macrophages and THP-1 cells: a potential mechanism of increased atherosclerosis in hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Apolipoproteins E; Arteriosclerosis; CD36 Antigens; Cell Adhesion; Cell Differentiation; Cells, Cultured; Cholesterol, Dietary; Disease Models, Animal; Humans; Hypertension; Immunohistochemistry; Losartan; Macrophages; Male; Membrane Proteins; Mice; Mice, Knockout; Monocytes; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Scavenger Receptors, Class A; Scavenger Receptors, Class B; Stress, Mechanical; Tetradecanoylphorbol Acetate; Transcription Factors | 2001 |
Load versus humoral activation in the genesis of early hypertensive heart disease.
Topics: Angiotensin II; Animals; Catecholamines; Diastole; Disease Models, Animal; Dogs; Endothelin-1; Heart Ventricles; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Kidney; Natriuretic Peptide, Brain; Propranolol; Renin; Systole; Ventricular Dysfunction, Left | 2001 |
Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Precursors; Hypertension; In Situ Hybridization; Indoles; Kidney; Kinetics; Mice; Pedigree; Peptidyl-Dipeptidase A; Precipitin Tests; Promoter Regions, Genetic; Rats; Rats, Inbred Strains; Renin; Time Factors; Transcription, Genetic; Transgenes | 2001 |
Angiotensin II type 2 receptor is essential for left ventricular hypertrophy and cardiac fibrosis in chronic angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Chronic Disease; Collagen; Diastole; Disease Models, Animal; Echocardiography; Echocardiography, Doppler; Endomyocardial Fibrosis; Fibronectins; Hypertension; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Systole; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Microcirculation in hypertension: a new target for treatment?
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Diuretics; Humans; Hypertension; Microcirculation; Rats; Rats, Inbred SHR | 2001 |
Cardioprotective effects of ramipril and losartan in right ventricular pressure overload in the rabbit: importance of kinins and influence on angiotensin II type 1 receptor signaling pathway.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin Receptor Antagonists; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; GTP-Binding Proteins; Hemodynamics; In Vitro Techniques; Kinins; Losartan; Male; Myocardial Contraction; Myocardium; Organ Size; Papillary Muscles; Protein Subunits; Pulmonary Artery; Rabbits; Ramipril; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Ventricular Dysfunction, Right | 2001 |
Up-regulation of parathyroid hormone-related protein in folic acid-induced acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Cell Division; Disease Models, Animal; Endothelin-1; Endothelins; Epithelial Cells; Folic Acid; Immunohistochemistry; Kidney Cortex; Kidney Tubules; Male; Parathyroid Hormone-Related Protein; Peptidyl-Dipeptidase A; Protein Precursors; Proteins; Rats; Rats, Wistar; Regeneration; Up-Regulation | 2001 |
Different reactivity to angiotensin II of peripheral and renal arteries in spontaneously hypertensive rats: effect of acute and chronic angiotensin converting enzyme inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Sodium, Dietary | 1986 |
Superior cavopulmonary anastomosis suppresses the activity and expression of pulmonary angiotensin-converting enzyme.
Topics: Angiotensin II; Animals; Arteriovenous Malformations; Biopsy; Blotting, Western; Disease Models, Animal; Echocardiography; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Heart Bypass, Right; Peptidyl-Dipeptidase A; Pulmonary Artery; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sheep; Time Factors | 2001 |
Role of angiotensin II and free radicals in blood pressure regulation in a rat model of renal hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Blotting, Western; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Hypertension, Renovascular; Losartan; Male; Nephrectomy; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; Renin; Spin Labels; Superoxides; Systole; Time Factors; Tyrosine | 2001 |
Interaction between sodium intake, angiotensin II, and blood pressure as a cause of cardiac hypertrophy.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiomegaly; Circadian Rhythm; Cross-Over Studies; Disease Models, Animal; France; Heart; Hypertension, Renovascular; Kidney; Losartan; Models, Cardiovascular; Organ Size; Rats; Rats, Wistar; Renin; Sodium, Dietary; Telemetry | 2001 |
Vascular responses to endothelin-1, angiotensin-II, and U46619 in glycerol-induced acute renal failure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Glycerol; In Vitro Techniques; Male; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Effects of central angiotensin II receptor antagonism on fetal swallowing and cardiovascular activity.
Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiovascular System; Deglutition; Disease Models, Animal; Female; Fetal Blood; Fetus; Heart Rate; Injections, Intraventricular; Pregnancy; Pregnancy, Animal; Probability; Receptors, Angiotensin; Reference Values; Saralasin; Sensitivity and Specificity; Sheep | 2001 |
Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Animals, Newborn; Binding, Competitive; Blood Pressure; Calcium; Cardiomegaly; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Heart Ventricles; Hemodynamics; Humans; Membranes; Myocardium; Organ Size; Perfusion; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Time Factors; Transgenes | 2001 |
Diverse effects of chronic treatment with losartan, fosinopril, and amlodipine on apoptosis, angiotensin II in the left ventricle of hypertensive rats.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; China; Disease Models, Animal; Fosinopril; Heart Ventricles; Hypertrophy, Left Ventricular; Losartan; Models, Cardiovascular; Myocardium; Random Allocation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1 | 2001 |
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy.
Topics: ADAM Proteins; ADAM12 Protein; Angiotensin II; Animals; Aorta, Thoracic; Cardiomegaly; Disease Models, Animal; Disintegrins; Epidermal Growth Factor; ErbB Receptors; Glycine; GTP-Binding Proteins; Heart Ventricles; Heparin-binding EGF-like Growth Factor; Hydroxamic Acids; Hypertension; Intercellular Signaling Peptides and Proteins; Male; Membrane Proteins; Metalloendopeptidases; Phenylephrine; Protease Inhibitors; Protein Processing, Post-Translational; Rats; Signal Transduction; Systole; Transcriptional Activation | 2002 |
Downregulation of ANG II receptor is associated with compensated pressure-overload hypertrophy in the young dog.
Topics: Adaptation, Physiological; Age Factors; Angiotensin II; Animals; Aorta; Arrhythmias, Cardiac; Blood Pressure; Cardiac Volume; Cardiomegaly; Disease Models, Animal; Dogs; Down-Regulation; Electrophysiology; Gene Expression; Muscle Fibers, Skeletal; Myocardium; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Ventricular Function, Left | 2002 |
[The role of cyclin-dependent kinase inhibitors in hyperplasia and hypertrophy of vascular smooth muscle cells].
Topics: Angiotensin II; Animals; Becaplermin; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Cyclins; Disease Models, Animal; Gene Expression; Hyperplasia; Hypertrophy; Male; Muscle, Smooth, Vascular; Nuclear Proteins; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Tumor Suppressor Proteins | 2001 |
Interactions of the renin-angiotensin system and alpha-1 adrenoceptors on renal hemodynamics in healthy and acute renal failure rats: the role of nitric oxide.
Topics: Acetylcholine; Acute Kidney Injury; Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Hemodynamics; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Renal Circulation; Renin-Angiotensin System | 2001 |
Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Biological Availability; Biphenyl Compounds; Blood Pressure; Blood Vessels; Disease Models, Animal; Drug Therapy, Combination; Female; Hypertension; Immunohistochemistry; Irbesartan; Male; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide; Phosphoproteins; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Stroke; Superoxides; Tetrazoles | 2002 |
Angiotensin II fails to induce preconditioning in vivo--the protective role of myocardial stretch due to pressure overload.
Topics: Angiotensin II; Animals; Disease Models, Animal; Gadolinium; Hemodynamics; Infusions, Intravenous; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Revascularization; Pressure; Rabbits; Reference Values; Sensitivity and Specificity | 2002 |
Effects of different durations of pretreatment with losartan on myocardial infarct size, endothelial function, and vascular endothelial growth factor.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Disease Models, Animal; Endothelial Growth Factors; Endothelium, Vascular; Female; Losartan; Lymphokines; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Renin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilation | 2001 |
Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading.
Topics: Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Eplerenone; Heart Diseases; Male; Mineralocorticoid Receptor Antagonists; NG-Nitroarginine Methyl Ester; Potassium; Rats; Rats, Wistar; Spironolactone | 2002 |
Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Epoxide Hydrolases; Hypertension; Male; Rats; Rats, Sprague-Dawley | 2002 |
Functional significance of activation of calcium/calmodulin-dependent protein kinase II in angiotensin II--induced vascular hyperplasia and hypertension.
Topics: Angiotensin II; Animals; Blood Vessels; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Disease Models, Animal; DNA; Enzyme Activation; Hyperplasia; Hypertension; Male; Norepinephrine; Phosphorylation; Rabbits; Rats; Rats, Sprague-Dawley | 2002 |
Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cell Adhesion Molecules; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Infusions, Parenteral; Membrane Glycoproteins; Membrane Transport Proteins; Microfilament Proteins; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH Dehydrogenase; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphoproteins; Protein Kinase C; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Superoxides; Vasodilation; Vasodilator Agents | 2002 |
Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo.
Topics: Actins; Angiotensin II; Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Cell Size; Cells, Cultured; Chromans; Disease Models, Animal; Gene Expression; Heart; Heterozygote; Hypoglycemic Agents; Ligands; Mice; Mice, Knockout; Myocardium; Organ Size; Pioglitazone; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
Angiotensin II receptor blockade does not improve left ventricular function and remodeling in subacute mitral regurgitation in the dog.
Topics: Alabama; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Chymases; Disease Models, Animal; Dogs; Female; Heart Ventricles; Hemodynamics; Male; Mitral Valve Insufficiency; Receptor, Angiotensin, Type 1; Renin; Serine Endopeptidases; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2002 |
Stage-dependent activation of cell cycle and apoptosis mechanisms in the right ventricle by pressure overload.
Topics: Angiotensin II; Animals; Apoptosis; Cell Cycle; Disease Models, Animal; Heart; Heart Ventricles; Hypertrophy, Left Ventricular; Immunohistochemistry; Myocardium; Pressure; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Aortic smooth muscle cell phenotypic modulation and fibrillar collagen deposition in angiotensin II-dependent hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta; Biphenyl Compounds; Bosentan; Calcium Channel Blockers; Collagen; Dansyl Compounds; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Immunohistochemistry; Irbesartan; Male; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles | 2002 |
Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Collagen; Cyclooxygenase 2; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Endothelial Growth Factors; Female; Imidazoles; Isoenzymes; Laminin; Lymphokines; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfonamides; Tetrazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Angiogenesis and antifibrotic action by hepatocyte growth factor in cardiomyopathy.
Topics: Angiotensin II; Animals; Blood Vessels; Cardiomyopathy, Dilated; Cricetinae; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression Regulation; Genetic Therapy; Hepatocyte Growth Factor; Humans; Injections, Intramuscular; Mesocricetus; Plasmids; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; RNA, Messenger; Transcription Factors; Transforming Growth Factor beta | 2002 |
beta-Adrenergic blockade reduces the severity of acute renal failure in rats.
Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Angiotensin II; Animals; Creatinine; Disease Models, Animal; Female; Hypoxia; Propranolol; Rats; Renin; Uremia | 1976 |
Adrenergaically mediated ventricular fibrillation in probucol-treated dogs: roles of alpha and beta adrenergic receptors.
Topics: Angiotensin II; Animals; Death, Sudden; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Epinephrine; Isoproterenol; Phenols; Phenylephrine; Probucol; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stellate Ganglion; Stress, Physiological; Vagus Nerve; Ventricular Fibrillation | 1979 |
Angiotensin binding affinity and capacity in the midbrain area of spontaneously hypertensive and normotensive rats.
Topics: Age Factors; Angiotensin II; Animals; Disease Models, Animal; Hypertension; Hypothalamus; Mesencephalon; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Septal Nuclei; Thalamus | 1978 |
Inhibitors of the renin-angiotensin system in experimental hypertension, with a note on the measurement of angiotensin I, II and III during infusion of converting-enzyme inhibitor.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Dogs; Female; Hypertension, Renal; Male; Oligopeptides; Proline; Rats; Saralasin; Teprotide | 1979 |
Effects of the oral converting enzyme inhibitor, SQ 14225, in a model of low cardiac output in dogs.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Ascites; Blood Pressure; Cardiac Output; Constriction; Creatinine; Disease Models, Animal; Dogs; Edema; Female; Heart Failure; Kidney; p-Aminohippuric Acid; Proline; Renin; Sodium; Vena Cava, Superior | 1979 |
Upper limit of cerebral blood flow autoregulation in experimental renovascular hypertension in the baboon.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Disease Models, Animal; Hemoglobins; Homeostasis; Hydrogen-Ion Concentration; Hypertension, Renal; Oxygen; Papio; Partial Pressure; Renal Artery Obstruction; Xenon Radioisotopes | 1975 |
The pathophysiology of renal hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Constriction; Disease Models, Animal; Dogs; Humans; Hypertension, Renal; Juxtaglomerular Apparatus; Rats; Renal Artery; Renin | 1977 |
Dopamine and saralasin antagonism of renal vasoconstriction and oliguria caused by amphotericin B in dogs.
Topics: Amphotericin B; Angiotensin II; Animals; Anuria; Disease Models, Animal; Dogs; Dopamine; Female; Glomerular Filtration Rate; Kidney; Lung; Oliguria; Saralasin; Vascular Resistance | 1979 |
[Renin-angiotensin system and hypertension. Morphology and function of the secretorily insufficient juxtaglomerular apparatus].
Topics: Angiotensin II; Animals; Blood Volume; Disease Models, Animal; Hypertension, Renal; Hypotension; Juxtaglomerular Apparatus; Rats; Renin; Sodium | 1977 |
Effect of angiotensin II inhibition in the bile-duct-ligated dog.
Topics: Angiotensin II; Animals; Bile Ducts; Disease Models, Animal; Dogs; Female; Humans; Kidney Tubules; Ligation; Liver Cirrhosis, Experimental; Saralasin; Sodium | 1978 |
Study of sar-ala8 angiotensin II (saralasin) responsiveness in hypertension of renal origin.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dogs; Hypertension, Renal; Nephrectomy; Renin; Saralasin | 1978 |
Urea-induced proteinuria: a new experimental model.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dogs; Female; Inulin; Kidney Glomerulus; Male; Proteinuria; Urea | 1978 |
[Experimental hypertensions].
Topics: Angiotensin II; Animals; Blood Vessels; Cats; Central Nervous System; Denervation; Desoxycorticosterone; Disease Models, Animal; Dogs; Heart; Hypertension; Kidney; Pressoreceptors; Rats; Renin; Sodium Chloride; Sympathetic Nervous System; Water-Electrolyte Balance | 1978 |
[Modeling cerebral dropsy (hydrocephalus) in animals by using angiotensin II].
Topics: Angiotensin II; Animals; Brain; Disease Models, Animal; Humans; Hydrocephalus; Male; Rats | 1978 |
Intrarenal renin-angiotensin-sodium interdependent mechanism controlling postclamp renal artery pressure and renin release in the conscious dog with chronic one-kidney Goldblatt hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Dogs; Feedback; Female; Hypertension, Renal; Renal Artery Obstruction; Renin; Sodium; Vascular Resistance | 1977 |
The renin-angiotensin-aldosterone system in rabbits with congestive heart failure produced by aortic constriction.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Constriction, Pathologic; Dexamethasone; Disease Models, Animal; Heart Failure; Hematocrit; Lung; Male; Natriuresis; Pulmonary Edema; Rabbits; Renin; Sodium | 1977 |
Prostaglandins and the renin-angiotensin system in canine endotoxemia.
Topics: Angiotensin II; Animals; Disease Models, Animal; Dogs; Female; Hemodynamics; Indomethacin; Kidney; Male; Mesentery; Prostaglandins; Renin; Shock, Septic; Time Factors; Vascular Resistance | 1977 |
Exaggerated prostaglandin biosynthesis and its influence on renal resistance in the isolated hydronephrotic rabbit kidney.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Arachidonic Acids; Bradykinin; Disease Models, Animal; Hydronephrosis; Indomethacin; Kidney; Ligation; Male; Norepinephrine; Prostaglandins; Rabbits; Ureter | 1977 |
Mechanisms involved in two-kidney renal hypertension induced by constriction of one renal artery.
Topics: Adrenal Cortex Hormones; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Disease Models, Animal; Dogs; Female; Hypertension, Renal; Male; Methods; Potassium; Rabbits; Renal Artery Obstruction; Renin; Saralasin; Sodium | 1977 |
Beneficial effect of propranolol in a histologically appropriate model of postischemic acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Drinking; Female; Hypotension; Ischemia; Kidney; Propranolol; Rabbits; Radiography; Regional Blood Flow; Renal Artery; Renin; Vasomotor System | 1977 |
Alleviation of anoxic experimental acute renal failure in rats by beta-adrenergic blockade.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Nitrogen; Propranolol; Prostaglandins A; Rats | 1977 |
Brain and kidney renin-angiotensin activity in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Brain Stem; Cerebral Cortex; Disease Models, Animal; Female; Hypertension; Kidney; Male; Medulla Oblongata; Rats; Renin; Rodent Diseases | 1977 |
[Significance of renin-angiotensin system inhibitors in the diagnosis of hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dogs; Enzyme Inhibitors; Humans; Hypertension; Pindolol; Propranolol; Rats; Renal Artery Obstruction; Renin; Saralasin | 1977 |
Proceedings: Relationship between cathecholamine and renin-angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Catecholamines; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Male; Rats; Renin | 1976 |
[Angiotensin-induced hypertension in pigs].
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Myocardium; Swine | 1976 |
[Therepeutic effect of an angiotensin II antagonist in experimental malignant nephrosclerosis].
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Nephrosclerosis; Rats | 1976 |
Endocrine-type antihypertensive function of renomedullary interstitial cells.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Connective Tissue; Connective Tissue Cells; Disease Models, Animal; Hypertension, Renal; Indomethacin; Kidney; Kidney Medulla; Prostaglandins; Rats; Renal Artery Obstruction; Sodium; Transplantation, Homologous; Water-Electrolyte Balance | 1975 |
The sausage-string pattern in the pial vessels in acute, angiotensin-induced hypertension--vasospasm or vasodilatation?
Topics: Angiotensin II; Animals; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Homeostasis; Hypertension; Pia Mater; Rats; Vascular Diseases; Vasomotor System | 1976 |
Changes in plasma renin substrate, plasma and renal renin, and plasma osmolarity during glycerol-induced acute renal failure in rabbits.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Creatinine; Disease Models, Animal; Glycerol; Injections, Subcutaneous; Kidney; Male; Osmolar Concentration; Plasma; Potassium; Rabbits; Renin; Sodium; Time Factors | 1975 |
Reciprocation of renin dependency with sodium volume dependency in renal hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Disease Models, Animal; Hypertension, Renal; Male; Rats; Renal Artery Obstruction; Renin; Saralasin; Sodium | 1975 |
Role of angiotensin II in experimental renal hypertension in the rabbit.
Topics: Angiotensin II; Animals; Blood Pressure; Constriction; Disease Models, Animal; Hypertension, Renal; Male; Nephrectomy; Rabbits; Renin; Sodium; Time Factors | 1975 |
[Effect of angiotensin II on the pattern of plasma free fatty acids in 2 hypertension models in rabbits].
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Fatty Acids, Nonesterified; Hypertension; Hypertension, Renal; Male; Rabbits; Time Factors | 1975 |
[Ultrastructural observations in the lamina elastica interna and adjacent tissue regions of the arterioles of rats impaired by hypertension of different pathogenesis (author's transl)].
Topics: Angiotensin II; Animals; Descemet Membrane; Disease Models, Animal; Elastic Tissue; Endothelium; Hypertension; Male; Rats | 1975 |
Studies of plasma renin activity in coarctation of the aorta.
Topics: Adolescent; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Child; Diazoxide; Disease Models, Animal; Dogs; Hematocrit; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Male; Physical Exertion; Potassium; Renin; Sodium | 1976 |
A scanning electron microscopic study of the glycerol model of acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Female; Glycerol; Kidney Glomerulus; Male; Microscopy, Electron, Scanning; Rats | 1976 |
[Animal models of various hypertensions].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Androgens; Angiotensin II; Animals; Catecholamines; Choline Deficiency; Disease Models, Animal; Glycyrrhiza; Growth Hormone; Hypertension; Metyrapone; Plants, Medicinal; Rats; Renin; Sodium, Dietary; Streptozocin | 1992 |
[Electromechanical responsiveness to alpha 1-adrenoceptor and angiotensin II receptor stimulation in the ventricular myocardium of hypertrophied and dilated cardiomyopathic Syrian hamsters].
Topics: Action Potentials; Angiotensin II; Animals; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Cricetinae; Disease Models, Animal; Electric Stimulation; In Vitro Techniques; Mesocricetus; Myocardial Contraction; Papillary Muscles; Phenylephrine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Angiotensin | 1992 |
Impact of enalapril therapy on in vitro coronary artery responsiveness in pacing-induced heart failure.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Animals; Cardiac Pacing, Artificial; Coronary Vessels; Disease Models, Animal; Dogs; Enalapril; Endothelium, Vascular; Heart Failure; In Vitro Techniques; Male; Vasoconstriction | 1992 |
Reactive and reparative myocardial fibrosis in arterial hypertension in the rat.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Collagen; Disease Models, Animal; Fibrosis; Hypertension, Renovascular; Male; Myocardium; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Spironolactone | 1992 |
Renal insensitivity to atrial natriuretic peptide in patients with cirrhosis and ascites.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Disease Models, Animal; Humans; Kidney; Liver Cirrhosis; Norepinephrine; Rats | 1992 |
An unsaturated fat diet prevents the increased angiotensin II vascular responses in renal artery stenosis.
Topics: Angiotensin II; Animals; Dietary Fats, Unsaturated; Disease Models, Animal; Hypertension, Renovascular; Kidney; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vascular Resistance | 1992 |
[Renovascular hypertension: etiological classification and procedures for diagnosis].
Topics: Angiotensin II; Animals; Disease Models, Animal; Humans; Hypertension, Renovascular; Kallikreins; Kinins; Radioisotope Renography; Renal Artery; Renin; Urography | 1992 |
Development of a high renin model of hypertension in the cynomolgus monkey.
Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Disease Models, Animal; Hypertension, Renovascular; Macaca fascicularis; Male; Oligopeptides; Renal Artery Obstruction; Renin; Saralasin | 1991 |
Myocardial fibrosis: role of ventricular systolic pressure, arterial hypertension, and circulating hormones.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endomyocardial Fibrosis; Hypertension, Renovascular; Renin; Renin-Angiotensin System | 1991 |
Hemodynamic effects of direct angiotensin II blockade compared to converting enzyme inhibition in rat model of heart failure.
Topics: Administration, Oral; Angiotensin II; Animals; Body Weight; Captopril; Cardiac Output, Low; Compliance; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Hemodynamics; Imidazoles; Losartan; Male; Myocardial Infarction; Rats; Rats, Inbred Strains; Tetrazoles; Ventricular Function, Left | 1991 |
Isolation and characterization of chicken mesangial cells.
Topics: Angiotensin II; Animals; Autoimmune Diseases; Cell Division; Cell Separation; Cells, Cultured; Chickens; Disease Models, Animal; Fibroblasts; Fluorescent Antibody Technique; Glomerular Mesangium; Glomerulonephritis; Microscopy, Electron; Phagocytosis; Protein Binding | 1991 |
Reversal of low dose angiotension hypertension by angiotensin receptor antagonists.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Infusions, Intravenous; Male; Rats; Rats, Inbred Strains; Saralasin | 1991 |
Modulation of splanchnic vascular sensitivity to angiotensin II.
Topics: Angiotensin II; Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Epoprostenol; Hypertension, Portal; Indomethacin; Male; Mesenteric Arteries; Rabbits; Splanchnic Circulation; Vascular Resistance | 1991 |
Effect of delapril on the vascular angiotensin II release in isolated hind legs of the spontaneously hypertensive rat: evidence for potential relevance of vascular angiotensin II to the maintenance of hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Indans; Muscle, Smooth, Vascular; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System | 1991 |
[Humoral factors of regulation of water-salt metabolism in experimental traumatic brain edema].
Topics: Aldosterone; Angiotensin II; Animals; Brain; Brain Edema; Brain Injuries; Disease Models, Animal; Potassium; Rats; Sodium; Time Factors; Vasopressins; Water-Electrolyte Balance | 1990 |
Vasopressin and angiotensin II contribute equally to the increased afterload in rabbits with heart failure.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Cardiac Output; Disease Models, Animal; Female; Heart Failure; Male; Rabbits; Vascular Resistance; Vasopressins | 1991 |
Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Disease Models, Animal; Enzyme Precursors; Gene Expression; Hypertension; Kidney; Mice; Mice, Inbred DBA; Rats; Renin; Submandibular Gland; Transfection | 1990 |
Effect of hypertension on fibronectin expression in the rat aorta.
Topics: Adipose Tissue, Brown; Age Factors; Angiotensin II; Animals; Aorta; Blotting, Northern; Blotting, Western; Collagen; Desoxycorticosterone; Disease Models, Animal; Fibronectins; Gene Expression; Hypertension; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred Strains; RNA, Messenger; Tropoelastin | 1990 |
Efficacy of the glyceryl trinitrate transdermal therapeutic system in a dog model of myocardial ischaemia.
Topics: Administration, Cutaneous; Angiotensin II; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Delayed-Action Preparations; Disease Models, Animal; Dogs; Electrocardiography; Female; Heart Rate; Male; Nitroglycerin | 1989 |
Angiotensin II and atrial natriuretic factor-binding sites in various tissues in hypertension: comparative receptor localization and changes in different hypertension models in the rat.
Topics: Adrenal Glands; Angiotensin II; Animals; Aorta; Atrial Natriuretic Factor; Brain; Brain Stem; Disease Models, Animal; Hypertension; Hypertension, Renovascular; Kidney Glomerulus; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Reference Values; Renin | 1989 |
Renin-angiotensin II response to the hemodynamic pathology of ovines with ventricular septal defect.
Topics: Angiotensin II; Animals; Captopril; Disease Models, Animal; Furosemide; Heart Septal Defects, Ventricular; Hemodynamics; Renin; Renin-Angiotensin System; Saralasin; Sheep; Sheep Diseases | 1989 |
Prevention of the normal expansion of maternal plasma volume: a model for chronic fetal hypoxaemia.
Topics: Angiotensin II; Animals; Blood Pressure; Bloodletting; Catecholamines; Disease Models, Animal; Female; Fetal Blood; Fetal Hypoxia; Furosemide; Heart Rate, Fetal; Hydrogen-Ion Concentration; Oxygen; Plasma Volume; Pregnancy; Regional Blood Flow; Renin; Sheep; Uterus; Vasopressins | 1989 |
Role of angiotensin II in experimental membranous nephropathy.
Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Blood Pressure; Disease Models, Animal; Enalapril; Glomerular Filtration Rate; Kidney Tubules, Proximal; Nephritis; Nephrons; Rats; Rats, Inbred Strains; Reference Values; Renin-Angiotensin System | 1988 |
The effects of coarctation hypertension upon vascular inositol phospholipid hydrolysis in Wistar rats.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Female; Hydrolysis; Hypertension; Ligation; Phosphatidylinositols; Rats; Rats, Inbred Strains; Renin | 1988 |
Does vasopressin sustain blood pressure in conscious spontaneously hypertensive rats?
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasopressins; Water Deprivation | 1986 |
Characterization of neurohormonal changes following the production of the benign and malignant phases of two-kidney, two-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Captopril; Catecholamines; Disease Models, Animal; Dogs; Epinephrine; Hexamethonium; Hexamethonium Compounds; Hypertension, Malignant; Hypertension, Renovascular; Neuropeptides; Norepinephrine; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1987 |
Hemodynamic effects of enalapril on neonatal chronic partial ureteral obstruction.
Topics: Angiotensin II; Animals; Animals, Newborn; Disease Models, Animal; Enalapril; Glomerular Filtration Rate; Guinea Pigs; Hemodynamics; Hydronephrosis; Kidney Glomerulus; Time Factors; Ureteral Obstruction; Vascular Resistance | 1985 |
Pathophysiology of hepatic ischemia in cardiogenic shock.
Topics: Angiotensin II; Animals; Cardiac Output; Central Venous Pressure; Disease Models, Animal; Hemodynamics; Ischemia; Liver; Renin; Renin-Angiotensin System; Shock, Cardiogenic; Splanchnic Circulation; Swine; Sympathetic Nervous System; Vascular Resistance | 1986 |
Role of 5-hydroxytryptamine in endotoxin-induced respiratory failure of pigs.
Topics: Acute Disease; Angiotensin II; Animals; Bronchi; Constriction, Pathologic; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Ketanserin; Norepinephrine; Prostaglandins F; Pulmonary Artery; Pulmonary Veins; Respiratory Insufficiency; Serotonin; Swine; Swine Diseases; Vascular Resistance | 1987 |
Elevated glucose utilization in the subfornical organ during dehydration.
Topics: Angiotensin II; Animals; Captopril; Dehydration; Deoxyglucose; Disease Models, Animal; Glucose; Infusions, Parenteral; Injections, Intravenous; Male; Neurosecretory Systems; Rats; Rats, Brattleboro; Rats, Inbred Strains; Subfornical Organ; Time Factors | 1985 |
Unilaterally nephrectomized rat with aortic ligation: a uremic model of severe hypertension.
Topics: Angiotensin II; Animals; Creatinine; Disease Models, Animal; Hypertension, Renovascular; Ligation; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renal Artery Obstruction; Renin; Uremia | 1985 |
Angiotensin-induced hypertension in conscious dogs: biochemical parameters and baroreceptor reflex.
Topics: Aldosterone; Angiotensin II; Animals; Body Weight; Consciousness; Disease Models, Animal; Dogs; Female; Heart Rate; Hypertension; Isoproterenol; Male; Pressoreceptors; Reflex; Renin | 1985 |
Baroreflex sensitivity and pressor responses in a rat model of uraemia.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Disease Models, Animal; Male; Norepinephrine; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Uremia | 1985 |
Sympathetic innervation of the juxtaglomerular cells of the kidney in rats with renal hypertension.
Topics: Adrenergic Agents; Angiotensin II; Animals; Disease Models, Animal; Female; Histocytochemistry; Hypertension, Renal; Juxtaglomerular Apparatus; Kidney; Microscopy, Fluorescence; Rats; Sympathetic Nervous System; Time Factors | 1972 |
[Plasma glucose concentration following experimental interventions in blood pressure homeostasis of rabbits. I. Effect of synthetic angiotensin II on the blood sugar level of normotonic and renal hypertonic experimental animals].
Topics: Angiotensin II; Animals; Blood Glucose; Disease Models, Animal; Female; Glucose Tolerance Test; Homeostasis; Hypertension, Renal; Male; Rabbits | 1969 |
Effects of renal artery constriction and subsequent contralateral nephrectomy on the blood pressure, plasma renin activity, and plasma renin substrate concentration in rabbits.
Topics: Angiotensin II; Animals; Blood Pressure; Cats; Disease Models, Animal; Dogs; Functional Laterality; Hematocrit; Humans; Kinetics; Male; Nephrectomy; Rabbits; Rats; Renal Artery; Renin; Stress, Psychological | 1970 |
The microcirculatory effects of endotoxin shock as evaluated by effects on interstitial fluid pressure.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Body Fluids; Central Venous Pressure; Disease Models, Animal; Dogs; Epinephrine; Methylprednisolone; Microcirculation; Norepinephrine; Phenoxybenzamine; Shock, Septic; Splenectomy | 1970 |
Renal-clip hypertension in rabbits immunized against angiotensin II.
Topics: Angiotensin II; Animals; Antibody Formation; Antigen-Antibody Reactions; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Iodine Isotopes; Kidney; Metabolic Clearance Rate; Nephrectomy; Norepinephrine; Rabbits; Radioimmunoassay; Renal Artery; Renin; Urea | 1970 |
Experimental left ventricular akinesis: results of excision.
Topics: Acetylcholine; Angiocardiography; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cineangiography; Disease Models, Animal; Dogs; Electric Countershock; Extracorporeal Circulation; Heart Ventricles; Hemodynamics; Isoproterenol; Myocardial Infarction; Pulmonary Edema; Ventricular Fibrillation | 1970 |
Plasma renin activity and the effects of deoxycorticosterone acetate in dogs with chronic left ventricular overload.
Topics: Acetates; Angiotensin II; Animals; Aorta, Thoracic; Chronic Disease; Desoxycorticosterone; Disease Models, Animal; Dogs; Heart; Heart Atria; Heart Failure; Methods; Natriuresis; Pulmonary Edema; Renin | 1970 |
Evaluation of antihypertensive drugs in dogs with angiotensin-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Dogs; Female; Hexamethonium Compounds; Hydralazine; Hypertension; Male; Nitrites; Sodium | 1971 |
Modified characteristics of the aortic baroreceptor activities in the spontaneously hypertensive rat.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Disease Models, Animal; Hypertension; Injections, Intravenous; Norepinephrine; Pressoreceptors; Rats | 1970 |
[Comparative gas chromatographic analysis of the FFA-pattern in the plasma in different models of hypertension in the rat].
Topics: Aldosterone; Angiotensin II; Animals; Chromatography, Gas; Disease Models, Animal; Fatty Acids, Nonesterified; Hypertension; Rats; Renin | 1971 |
Role of the pressor action of angiotensin II in experimental hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Culture Techniques; Desoxycorticosterone; Disease Models, Animal; Hypertension; Hypertension, Renal; Male; Norepinephrine; Phenylephrine; Rabbits; Rats; Renin; Tyramine; Vasoconstrictor Agents; Vasopressins | 1971 |
Angiotensin binding by receptor-like factors in plasma from seriously ill patients and an experimental dog model.
Topics: Angiotensin II; Animals; Constriction; Disease Models, Animal; Dogs; Humans; Ischemia; Receptors, Drug; Time Factors; Vascular Diseases | 1971 |
The renin-angiotensin system in acute renal failure in the rat.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Urea Nitrogen; Diet; Disease Models, Animal; Female; Glomerular Filtration Rate; Glycerol; Kidney; Rats; Renin; Sodium | 1971 |
Sodium and water excretion in dogs with renovascular hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Diuresis; Dogs; Hypertension, Renal; Hypertonic Solutions; Kidney Function Tests; Kidney Tubules; Renin; Sodium; Water; Water-Electrolyte Balance | 1971 |
[Sensitivity to pressor effects at late periods of time after onset of brain ischemia in rabbits].
Topics: Angiotensin II; Animals; Blood Pressure; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models, Animal; Ischemia; Male; Methods; Norepinephrine; Rabbits; Reticular Formation; Time Factors | 1971 |
Chronic hypertension in rabbits induced by bilateral placement of rigid casts around the carotid sinus regions.
Topics: Angiotensin II; Animals; Blood Pressure; Carotid Artery, Internal; Carotid Sinus; Constriction; Dental Cements; Disease Models, Animal; Heart Rate; Hypertension; Rabbits; Reflex | 1972 |
Experimental myocardial ischemia and infarction. Production of diffuse myocardial lesions in unanesthetized calves.
Topics: Angiotensin II; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Cardiac Output; Cattle; Coronary Vessels; Creatine Kinase; Disease Models, Animal; Electrocardiography; Heart Rate; Injections, Intra-Arterial; Lactates; Methods; Microspheres; Myocardial Infarction | 1972 |
[Cardiovascular effects of angiotensin II implantates on the intact unanesthesized rat. A contribution to produce a medium-term experimental hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Heart Rate; Hypertension; Male; Rats; Rats, Inbred Strains; Time Factors | 1972 |
Mechanisms regulating renin release in dogs with thoracic caval constriction.
Topics: Angiotensin II; Animals; Ascites; Blood Pressure; Constriction; Creatinine; Disease Models, Animal; Dogs; Female; Glomerular Filtration Rate; Heart Failure; Kidney; Natriuresis; Papaverine; Potassium; Propranolol; Receptors, Drug; Regional Blood Flow; Renal Artery; Renin; Sodium; Sympathetic Nervous System; Vena Cava, Inferior | 1972 |
Prevention of experimental renovascular hypertension by caval portal shunt.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Hypertension, Renal; Kidney; Liver; Male; Methods; Portacaval Shunt, Surgical; Rats; Regional Blood Flow; Renal Artery Obstruction; Renin | 1972 |
Angiotensin-sodium interaction in blood pressure maintenance of renal hypertensive and normotensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Hyponatremia; Male; Nephrectomy; Rats; Sodium; Water-Electrolyte Balance | 1973 |
[Studies on rats with long-term resistance hypertension induced by daily administration of delayed-action preparations of angiotensin].
Topics: Angiotensin II; Animals; Blood Pressure; Delayed-Action Preparations; Disease Models, Animal; Hypertension; Injections, Subcutaneous; Male; Rats; Time Factors | 1973 |
Prevention of malignant hypertension by the synthetic peptide SQ 20,881.
Topics: Angiotensin II; Animals; Arteries; Blood; Blood Pressure; Blood Urea Nitrogen; Bradykinin; Carbon Dioxide; Colon; Creatinine; Disease Models, Animal; Drug Synergism; Hydrogen-Ion Concentration; Hypertension, Malignant; Hypertension, Renal; Injections, Intramuscular; Intestinal Mucosa; Intestine, Small; Kidney Medulla; Male; Oligopeptides; Peptides; Rabbits; Renal Artery Obstruction; Time Factors; Transplantation, Autologous | 1974 |
Acute hypertension and prolonged focal cerebral ischemia.
Topics: Angiotensin II; Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Ischemic Attack, Transient; Rabbits | 1973 |
Cerebral blood flow in acute hypertension.
Topics: Anesthetics; Angiotensin II; Animals; Autoradiography; Blood Flow Velocity; Blood Pressure; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models, Animal; Hypertension; Methoxyflurane; Rabbits; Thiopental; Vasomotor System | 1974 |
Myocardial function and lipid metabolism in the chronic alcoholic animal.
Topics: Alcoholism; Angiotensin II; Animals; Blood Pressure; Carbon Radioisotopes; Cardiac Volume; Cardiomyopathies; Cell Membrane; Diet; Disease Models, Animal; Dogs; Ethanol; Heart; Heart Ventricles; Humans; Lipid Metabolism; Male; Myocardium; Oleic Acids; Phospholipids; Triglycerides; Vitamins; Water-Electrolyte Balance | 1974 |
[Importance of formatio reticularis mesencephali in experimental models of hypertension].
Topics: Angiotensin II; Animals; Blood Circulation; Blood Pressure; Carotid Sinus; Disease Models, Animal; Electric Stimulation; Electrocoagulation; Electrodes, Implanted; Female; Hemodynamics; Hypertension; Male; Mesencephalon; Rabbits; Reticular Formation | 1974 |
Acute renal failure in disseminated intravascular coagulation. Experimental studies of the induction and prevention of renal fibrin deposition.
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Angiotensin II; Animals; Anticoagulants; Blood Platelets; Disease Models, Animal; Disseminated Intravascular Coagulation; Endotoxins; Fibrin; Fibrinolysis; Kidney; Kidney Glomerulus; Mechlorethamine; Microscopy, Electron; Polymyxins; Pressure; Rabbits; Receptors, Adrenergic; Shwartzman Phenomenon; Thrombin; Thrombosis; Ureter | 1974 |
[Renin and sodium in blood pressure regulation].
Topics: Angiotensin II; Animals; Antibodies; Blood Pressure; Blood Volume; Disease Models, Animal; Homeostasis; Humans; Hypertension; Hypertension, Renal; Kidney; Renin; Sodium | 1974 |