Page last updated: 2024-08-22

angiotensin ii and Aortic Aneurysm, Abdominal

angiotensin ii has been researched along with Aortic Aneurysm, Abdominal in 439 studies

Research

Studies (439)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (0.23)18.2507
2000's54 (12.30)29.6817
2010's259 (59.00)24.3611
2020's125 (28.47)2.80

Authors

AuthorsStudies
Azuma, K; Goto, H; Masuyama, A; Mita, T; Mitsumata, M; Miyatsuka, T; Mochida, A; Nakajima, K; Nishida, Y; Osonoi, Y; Watada, H1
Bin, J; Cai, D; Chen, Y; Li, C; Liao, W; Liao, Y; Lin, Z; Ma, Y; Shi, X; Song, H; Sun, Y; Wei, G; Yang, Y; Zheng, H; Zhong, L1
Becares, M; Bermeo, H; Briones, AM; García-Redondo, AB; González-Amor, M; Guerra, S; Jorge, I; Martínez-González, J; Montezano, AC; Redondo, JM; Rios, FJ; Rodrigues-Díez, R; Rodríguez, C; Ruiz-Rodríguez, MJ; Salaices, M; Touyz, RM; Vázquez, J; Zalba, G1
Agic, MB; Kunath, A; Mani, K; Näsström, M; Petri, MH; Ramilo, AB; Wågsäter, D; Wanhainen, A1
Bian, H; Cho, K; Han, N; Jiang, B; Li, X; Wang, L; Wang, Y; Wu, P; Yin, J; Zhang, X; Zhang, Y1
Bai, Y; He, X; Huang, J; Le, T; Liu, S; Wu, K1
Duan, Z; Li, W; Li, X; Liu, Y; Wang, Z; Xiao, L; Zhong, Z1
Balboa Ramilo, A; Becirovic-Agic, M; Mani, K; Petri, MH; Wågsäter, D; Wanhainen, A1
Patrick, AC; Shridas, P; Tannock, LR1
Chen, X; Liu, X; Lou, J; Tang, L; Weng, Y; Xu, C1
Cassis, LA; Daugherty, A; Lu (吕红), HS; Sawada (澤田悠), H1
Agarwal, G; Annex, BH; Benson, TW; Blomkalns, AL; Fujise, K; Fukai, T; Fulton, DJ; Guha, A; Horimatsu, T; Huo, Y; Kim, HW; Lee, R; Long, X; Ogbi, M; Ushio-Fukai, M; Weintraub, NL; Winkler, MA; Young, L1
Chen, H; Guo, M; Hu, J; Peng, N; Qi, Y; Shen, S; Sun, X; Xu, B; Xu, J; Zhang, Q; Zhang, W; Zhang, Y1
Chang, WH; Lu, HY; Shih, CC; Wu, TC1
Li, J; Liao, S; Song, J; Wang, Y; Wei, W; Xu, Y; Xu, Z; Zhu, S1
Cassis, LA; de Beer, FC; Dugan, AJ; Ji, A; Leung, SW; Noffsinger, VP; Shridas, P; Tannock, LR; Thatcher, SE; Trumbauer, AC; Webb, NR1
Kraemer, M; Morris, AJ; Smyth, SS; Ubele, M; Van Hoose, PM; Yang, L1
Ao-Ieong, WS; Chen, CH; Ho, HH; Jiang, WC; Layne, MD; Orekhov, AN; Sobenin, IA; Wang, J; Yet, SF1
Chacar, S; Fares, N; Hajal, J; Jreije, A; Khouzami, L; Medlej-Hashim, M; Saliba, Y1
Bao, Y; Cai, C; Chen, X; Du, C; Lou, J; Tang, L; Weng, Y; Zhu, K1
Gao, A; Guo, X; Su, G; Wang, Z; Yu, F; Yu, L; Zhang, C; Zhang, J; Zhang, M; Zhang, Y1
Che, X; Chen, L; Chen, T; Geng, N; Lyu, Y; Shao, Q; Sun, L; Tao, Z; Xiao, Q; Zhang, H1
Ge, X; Lu, Y; Meng, L; Meng, X; Sui, W; Wang, X; Zhang, Y; Zhong, M1
Chao de la Barca, JM; Eid, M; Fassot, C; Faure, J; Fouquet, O; Henrion, D; Loufrani, L; Reynier, P; Richard, A; Robert, P; Tessier, L; Wetterwald, C1
Ding, S; Feng, ZH; Geng, N; Guo, X; Huang, L; Lin, GQ; Lin, N; Lyu, YY; Pu, J; Qian, K; Shen, Z; Sun, LY; Wang, YL; Yuan, AC; Zhang, HY; Zhang, L1
Hong, Y; Li, X; Lin, Y; Yang, H1
Bailey, MA; Bleichert, S; Brostjan, C; Busch, A; Eilenberg, W; Ibrahim, N; Klopf, J; Neumayer, C; Stiglbauer-Tscholakoff, A1
Fan, T; Feng, X; Gao, R; Ge, W; Guo, W; Hou, Y; Jin, M; Jing, H; Li, B; Lu, J; Pang, J; Wang, J; Yan, C; Zhang, T1
Daugherty, A; Hada, Y; Shikata, K; Subramanian, V; Takatsuka, T; Takeuchi, H; Uchida, HA; Umebayashi, R; Wada, J1
Chang, L; Chang, Z; Chen, YE; Garcia-Barrio, MT; Guo, Y; Liang, W; Lin, JD; Liu, H; Liu, Y; Lu, H; Rom, O; Wang, H; Yang, B; Zhang, J; Zhao, G; Zhao, Y; Zhu, T1
Alebrahim, D; Attur, M; Byrd, D; Harpel, Z; Lu, C; Maldonado, DJ; Mignatti, P; Pratama, MY; Ramkhelawon, B; Rivera, CF; Silvestro, M; Sleiman Tellaoui, R; Tang, C; Vlahos, J; Zias, AL1
De Meyer, GRY; De Moudt, S; Fransen, P; Hendrickx, JO; Martinet, W1
Chai, H; Chen, W; Chen, X; Fan, R; Hu, Y; Huang, F; Jiang, H; Liu, R; Zhou, Y1
Aono, J; Hamaguchi, M; Ikeda, S; Inoue, K; Kakino, A; Kurata, M; Nakao, Y; Sakaue, T; Sawamura, T; Suehiro, C; Suzuki, J; Takahashi, K; Yamaguchi, O1
Cai, H; Huang, K; Wu, Y; Youn, JY; Zhang, Y1
Cai, D; Chen, SY; Murashita, T; Que, X; Sun, C1
Furuyama, T; Hoshino, T; Kurose, S; Matsubara, Y; Morisaki, K; Yoshino, S; Yoshiya, K; Yoshizumi, T1
Huang, PH; Lin, SJ; Tsai, HY; Tsai, SH; Wang, JC1
Cicalese, SM; Eguchi, S; Hashimoto, T; Okuno, K; Rizzo, V; Sparks, MA; Torimoto, K1
Ding, Q; Du, Y; Li, H; Ma, T; Meng, Q; Sun, D; Zhang, X; Zhang, Z; Zheng, H; Zhuang, J1
Daugherty, A; Lu, HS; Sawada, H1
Han, Y; Liu, D; Liu, Y; Tian, X; Yan, C; Zhang, X1
Almendra-Pegueros, R; Consegal-Pérez, M; Galán, M; Jiménez-Altayó, F; Julve, J; Kassan, M; Martínez-González, J; Navas-Madroñal, M; Pérez, B; Puertas-Umbert, L; Rodriguez, C1
Cao, Y; Chai, H; Chen, G; Chen, W; Chen, X; Fan, R; Jiang, H; Liu, Y; Qin, W; Qiu, Z; Wang, X; Xu, Y; Yao, Y1
Guo, R; Li, Y; Tao, L; Xu, Y1
Chen, CY; Chen, JS; Chen, JW; Huang, PH; Lin, CP; Lin, SJ; Tzeng, IS; Wu, MY1
Bai, H; Ben, J; Chen, Q; Huang, J; Ji, R; Jia, Y; Jiang, B; Jiang, Y; Li, X; Wang, J; Wang, S; Yang, Q; Zhang, H; Zhou, Z; Zhu, X1
Chen, D; Du, Y; Du, Z; Hu, C; Jiao, X; Li, F; Li, L; Lv, Q; Qin, Y; Sun, Q; Wang, Y; Yang, Y; Yu, H; Zhang, J; Zhang, X1
Cai, Q; Davis, FM; Gallagher, KA; Gudjonsson, JE; Henke, PK; Joshi, AD; Mangum, K; Melvin, WJ; Tsoi, LC1
Ge, Y; Guo, J; Ikezoe, T; Li, Z; Qin, M; Shi, J; Shoji, T; Wang, Y; Xu, B1
Chen, Y; Lei, C; Li, F; Liu, B; Lv, Y; Song, W; Wu, J; Wu, X; Xie, T; Zheng, Y1
Chen, X; Fang, X; Jiang, J; Lau, H; Liu, X; Pryke, L; Tang, L; Vyas, P; Xu, B; Xu, C; Yao, L; Yu, L1
Adam, M; Ahdab, M; Baldus, S; Geißen, S; Guthoff, H; Hof, A; Landerer, M; Mehrkens, D; Mollenhauer, M; Niehues, J; Schäkel, J; Schorscher, M; von Stein, P; Winkels, H; Zimmermann, O1
Ballasy, NN; Belke, D; Fedak, PWM; Gomes, KP; Jadli, AS; Patel, VB; Wijesuriya, TM1
Kaga, S; Mori, K; Nakajima, H; Nakamura, S; Ogawa, Y; Okuma, H; Tsuchiya, K; Uchinuma, H1
Alramahi, A; Berzins, SP; Fang, Y; Golledge, J; Magliano, DJ; Nguyen, DT; Oqueli, E; Parker, K; Pyke, SJR; Sargisson, O; Thihlum, L; Wallace, ME; Wang, Y1
Alsac, JM; Arock, M; Caligiuri, G; Castier, Y; Clément, M; Coscas, R; Delbosc, S; Deschamps, L; Deschildre, C; Eggel, A; Even, G; Gaston, AT; Gautier, G; Guedj, K; Launay, P; Le Borgne, M; Loste, A; Louedec, L; Michel, JB; Morvan, M; Nicoletti, A; Procopio, E; Sénémaud, J1
Cao, M; Chen, X; Ding, J; Liao, M; Liao, Y; Qiu, Z; Wang, M; Wang, Y; Wu, H; Yan, X; Zhang, H; Zheng, J; Zhou, Y1
Dev, R; Dhakal, P; Guerau-de-Arellano, M; Hans, CP; Kuivaniemi, H; Partida-Sanchez, S; Ruiz-Rosado, JD; Sharma, N1
Da, J; Jin, X; Li, D; Li, G; Mi, L; Wang, Z; Xue, M1
Cheng, C; Cheng, J; Li, H; Lu, L; Ma, J; Sui, W; Xu, J; Xu, X; Xue, F; Yang, J; Zhang, C; Zhang, J; Zhang, M; Zhang, Y1
Aghayev, T; Eguchi, S; Fatkhullina, AR; Gankovskaya, LV; Khoreva, MV; Koltsova, EK; Kossenkov, AV; Makhov, P; Peshkova, IO; Sykes, SM; Tan, YF; Titerina, EK1
Golledge, J; Huynh, P; Jose, RJ; Krishna, SM; Lazzaroni, S; Moran, CS1
Ailawadi, G; Cullen, JM; Fashandi, AZ; Hawkins, RB; Lu, G; Mast, A; Montgomery, W; Salmon, M; Sharma, AK; Spinosa, M; Su, G; Upchurch, GR1
Agarwal, G; Ahmadieh, S; Benjamin, S; Benson, TW; Blomkalns, AL; Edgell, A; Fulton, DJ; Gilreath, N; Horimatsu, T; Huo, Y; Kim, D; Kim, HW; Mann, A; Moses, M; Offermanns, S; Ogbi, M; Patel, S; Pye, J; Reid, L; Robbins, N; Singh, N; Stansfield, BK; Thompson, A; Weintraub, NL1
Dweck, MR; Fletcher, AJ; Syed, MBJ1
Cicalese, S; Eguchi, S; Okuno, K1
Cao, XR; Dong, B; Dong, XF; Hei, NH; Kong, J; Li, JL; Ma, H; Wang, YL1
Ding, R; Hu, Y; Li, Q; Liu, Z; Lu, W; Xiao, H; Xie, D; Xie, J; Ye, B; Zheng, G; Zhong, L; Zhong, Y; Zhong, Z1
Chang, CW; Hsu, JH; Kuo, CH; Lai, CH; Lee, FT; Liu, CP; Wu, HL; Yeh, JL1
Cao, XR; Dong, B; Hei, NH; Li, JL; Ma, H; Wang, YL; Yan, WJ1
Cheng, Z; Fu, XM; Li, JM; Liao, XB; Peng, HL; Wu, QY; Zhang, GS; Zhao, Y; Zhou, XM; Zhou, YZ1
Li, H; Li, S; Liu, G; Shen, G; Sun, Q; Wang, H; Xu, Y; Yao, Y; Yuan, C1
Cheng, K; Cheng, Z; Yao, Y1
Liu, Z; Shen, J; Yin, L; Yue, J1
Cai, Z; Chen, Y; Fang, W; Fu, Y; Kong, W; Li, L; Li, Z; Sun, Y; Wang, L; Yang, L; Yao, F; Zhao, Z; Zhou, Y; Zhu, H1
Li, L; Li, Y; Ma, W; Pan, S; Shi, X; Tian, Y; Wang, H; Xu, C1
Biros, E; Golledge, J; Kleinschnitz, C; Krishna, SM; Moran, CS; Morton, SK; Panousis, C; Seto, SW1
Breyer, RM; Fujita, T; Goda, M; Hiromi, T; Ichikawa, Y; Ishikawa, Y; Ishiwata, R; Kurotaki, D; Mamun, A; Masuda, M; Minami, T; Nishihara, H; Suzuki, S; Takeuchi, I; Tamura, T; Uchida, K; Umemura, M; Yasuda, S; Yokoyama, U1
Chen, L; FitzGerald, GA; Jiang, T; Monslow, J; Puré, E; Tang, SY; Todd, L; Yang, G; Zhang, J1
Agarwal, G; Albert, B; Calomeni, EP; Debski, A; Gadde, N; Go, MR; Hans, CP; Jones, B; Mahajan, A; Sharma, N; Tonniges, JR; Yeung, DA1
Chang, L; Chang, Z; Chen, YE; Fan, Y; Garcia-Barrio, MT; Guo, Y; Liang, W; Lu, H; Rom, O; Sun, J; Wang, H; Xiong, W; Zhang, J; Zhao, G; Zhao, Y; Zhu, T1
Choi, ET; Cicalese, S; Cooper, HA; Eguchi, S; Kasahara, S; Kawai, T; Okuno, K; Otaka, N; Preston, KJ; Rizzo, V; Scalia, R; Uchida, HA1
Belenchia, AM; Hans, CP; Pulakat, L; Sharma, N; Toedebusch, R1
Khalil, RA; Li, L; Li, Y; Ma, W; Pan, S; Wang, B; Wang, H1
Achilefu, S; Deng, Z; Libby, P; Liu, CL; Liu, T; Liu, X; Nahrendorf, M; Shi, GP; Sukhova, GK; Tang, R; Wang, X; Wang, Y; Wojtkiewicz, GR; Zhang, JY1
Chen, Z; Li, H; Pan, Y; Wang, G; Zhang, H1
Bin, J; Feng, X; He, X; Lai, Y; Liao, W; Liao, Y; Song, H; Wei, G; Xu, T; Yang, Y; Zheng, H; Zhong, L1
Li, L; Li, Y; Ma, W; Pan, S; Pan, Y; Shi, X; Tian, Y; Wang, H; Xu, C1
Bumdelger, B; Ishida, M; Karasaki, K; Kokubo, H; Otani, M; Sakai, C; Yoshizumi, M1
Chen, X; Lio, I; Liu, J; Wang, S; Wei, Z; Xiao, J; Yang, C; Zhang, H1
Grochot-Przęczek, A; Hajduk, K; Józkowicz, A; Klóska, D; Kopacz, A; Neumayer, C; Piechota-Polanczyk, A; Werner, E1
Brangsch, J; Buchholz, R; Hamm, B; Karst, U; Klopfleisch, R; Kosch, O; Makowski, MR; Mangarova, DB; Mohtashamdolatshahi, A; Paysen, H; Schnorr, J; Taupitz, M; Wiekhorst, F1
Chen, S; Chen, Y; Cui, L; Li, F; Liu, B; Liu, Z; Shao, J; Yang, D; Zhang, H; Zheng, Y1
Li, Q; Liu, HL; Liu, X; Ma, D; Shi, WB; Suzuki, T; Wen, JK; Zhang, XH; Zhao, YB; Zheng, B1
Davis, FM; Obi, AT1
Cai, Z; Huang, J; Ou, Y; Pan, B; Wang, W; Wang, X; Yang, J; Yang, P1
Cho, MJ; Jeong, SJ; Jung, IH; Kim, S; Ko, NY; Lee, SH; Min, JK; Oh, GT; Park, JG1
Clarke, MW; Golledge, J; Krishna, SM; Moran, CS; Morton, SK; Moxon, JV; Nsengiyumva, V; Seto, SW1
Aslanidou, L; Di Lorenzo, A; Lovric, G; Sasset, L; Stergiopulos, N; Trachet, B1
Kurashiki, T; Miyake, T; Morishita, R; Nakagami, H; Nishimura, M1
Chau, LY; Chen, IM; Chen, JW; Chen, YH; Chiang, MT; Hsu, FF; Hsu, YW; Huang, PH; Leu, HB; Liu, FT; Tsai, MS1
Li, X; Lu, Y; Ma, Q; Tan, H; Tie, Y; Zhang, X1
Cai, L; Ding, Y; Fu, W; Li, X; Shi, Z; Tang, H; Xie, T; Zhou, M1
Furuta, M; Ishida, Y; Kimura, A; Kondo, T; Kuninaka, Y; Mukaida, N; Nosaka, M; Taruya, A1
Ait-Oufella, H; Al-Rifai, R; Boissonnas, A; Boufenzer, A; Bruneval, P; Chinetti, G; Clauser, E; Derive, M; Esposito, B; Giraud, A; Guerin, C; Guyonnet, L; Joffre, J; Lang, S; Lareyre, F; Laurans, L; Mallat, Z; Pinet, F; Raffort, J; Santos-Zas, I; Silvestre, JS; Soulat-Dufour, L; Taleb, S; Tedgui, A; Vandestienne, M; Vilar, J; Zhang, Y1
Han, Y; Liu, D; Tian, X; Wang, S; Yan, C; Zhang, X1
Arshad, M; Böckler, D; Dihlmann, S; Hakimi, M; Peters, AS; Wortmann, M1
Egashira, K; Katsuki, S; Koga, JI; Matoba, T; Nakano, K; Nakashiro, S; Tsutsui, H; Umezu, R1
Grochot-Przęczek, A; Hajduk, K; Józkowicz, A; Klóska, D; Kopacz, A; Piechota-Polańczyk, A; Werner, E1
Chen, Y; Du, J; Jia, LX; Jia, MZ; Liu, X; Lu, WW; Ni, XQ; Ning, ZP; Qi, YF; Ren, JL; Tang, CS; Yu, YR; Zhang, LS; Zhang, YR; Zhu, Q1
Chen, Y; Lai, S; Li, F; Li, Y; Liu, B; Sun, B; Wang, H; Wang, W; Zhang, X; Zheng, Y1
Gao, P; LeMaire, SA; Long, X; Luo, W; Maegdefessel, L; Miano, JM; Shan, S; Shen, YH; Singer, HA; Slivano, OJ; Tabuchi, A; Zhang, W; Zhao, J1
Chen, J; Chen, L; Chen, Q; Deng, N; Li, W; Liu, D; Shi, L; Si, X; Song, H; Sun, W; Wang, L; Zhang, J; Zhong, L; Zhou, W1
Balakrishnan, A; Howatt, DA; Javidan, A; Jiang, W; Moorleghen, JJ; Muniappan, L; Okuyama, M; Saido, TC; Subramanian, V; Thiagarajan, D; Uchida, HA; Yang, L1
Audu, C; Billi, AC; Daugherty, A; Davis, FM; denDekker, A; Gallagher, KA; Gudjonsson, JE; Joshi, AD; Kunkel, SL; Lu, HS; Melvin, WJ; Moore, BB; Obi, AT; Tsoi, LC; Wasikowski, R; Wolf, S; Xing, X1
Bruche, S; Channon, KM; Davies, R; Dubé, KN; Fischer, R; Handa, A; Hester, SS; Jones, A; Lee, R; Munshaw, S; Neal, G; Patel, J; Redpath, AN; Sattler, M; Smart, N1
Dhital, S; Eberth, JF; Hasanain, S; Lane, BA; Lessner, SM; Nosoudi, N; Parasaram, V; Vyavahare, NR; Wang, X1
Daugherty, A; Howatt, DA; Kukida, M; Lu, HS; Moorleghen, JJ; Ohno-Urabe, S; Poglitsch, M; Sawada, H1
Boodagh, P; Ghim, M; Gona, K; Graham, M; Han, J; Jung, JJ; Kukreja, G; Liu, X; Rajendran, S; Sadeghi, MM; Salarian, M; Sanzida, N; Toczek, J; Wei, L; Zhang, J1
Althagafi, MG; Besla, R; Byrne, JS; Chen, Y; Cybulsky, MI; Li, A; Lindsay, T; Pacheco, S; Robbins, CS; Ulndreaj, A1
Arendt, BK; Ebtehaj, S; Franchi, F; Lanza, IR; Parvizi, M; Rodriguez-Porcel, M1
Bando, YK; Fang, L; Hiramatsu-Ito, M; Kato, K; Kawanishi, H; Murohara, T; Ogawa, H; Ohashi, K; Otaka, N; Ouchi, N; Ozaki, Y; Shibata, R; Shimizu, Y; Takefuji, M; Takikawa, T1
Huang, Y; Pan, Y; Xie, C; Xie, X; Ye, F; Zhang, N1
Cai, L; Ding, Y; Li, X; Shi, Z; Tang, H; Zhou, M1
Cai, Y; Long, X; Lou, D; Mohan, A; Shi, H; Wang, J; Xiong, J; Yan, C; Zhang, C; Zhang, Y; Zhao, H1
Antoniadou, C; Arelaki, S; Argyriou, C; Chrysanthopoulou, A; Georgiadis, GS; Giatromanolaki, A; Gkaliagkousi, E; Lazaridis, A; Mitsios, A; Ntinopoulou, M; Papadopoulos, V; Pateinakis, P; Ritis, K; Skendros, P1
Dong, N; Klenotic, PA; Li, R; Lin, Z; Narla, G; Wang, Y; Wei, W; Xie, F; Xu, Q; Zhang, C; Zhou, X1
Balboa, A; Becirovic-Agic, M; Busch, A; de Waard, V; Gäbel, G; Golledge, J; Holdt, LM; Lindeman, JHN; Ludwig, S; Maegdefessel, L; Mahlmann, A; Northoff, BH; Petri, M; Teupser, D; Wågsäter, D; Wanhainen, A1
Clancy, P; Crossman, DJ; Emeto, TI; Golledge, J; Jose, R; Krishna, SM; Li, J; Moxon, J; Norman, P; Seto, SW1
Li, Y; Lu, G; Sun, D; Wang, DW; Yan, J; Zuo, H1
Balakrishnan, A; Da Cunha, V; Dajee, M; Daugherty, A; Gutstein, DE; Howatt, DA; Johns, DG; Lu, H; Moorleghen, J; Rateri, DL; Xie, X1
Chang, BI; Cheng, TL; Kuo, CH; Lai, CH; Lee, FT; Shi, GY; Wang, KC; Wu, HL; Yang, YJ1
Ait-Oufella, H; Cabuzu, D; Esposito, B; Giraud, A; Joffre, J; Kluwe, J; Lafont, A; Mallat, Z; Potteaux, S; Seguier, S; Tedgui, A; Vandestienne, M; Vilar, J; Zeboudj, L1
Chen, K; Wang, Q; Yan, P; Yang, D; Yang, Y1
Airhart, N; Angelov, SN; Dichek, DA; Hu, JH; Shi, M; Wei, H1
Amin, HZ; Emoto, T; Fukunaga, A; Hayashi, T; Hirata, KI; Kasahara, K; Kitano, N; Matsumoto, T; Mizoguchi, T; Nishigori, C; Rikitake, Y; Sasaki, N; Tabata, T; Yamashita, T; Yodoi, K; Yoshida, N1
Aoki, H; Baba, O; Hasegawa, K; Horie, T; Ide, Y; Izuhara, M; Kimura, M; Kimura, T; Koyama, S; Kuwabara, Y; Minatoya, K; Nakao, T; Nakazeki, F; Nishi, H; Nishiga, M; Nishino, T; Ohno, S; Ono, K; Sakamoto, K; Sowa, N; Usami, S1
Aslanidou, L; Fraga-Silva, RA; Piersigilli, A; Segers, P; Sordet-Dessimoz, J; Stampanoni, MFM; Stergiopulos, N; Trachet, B; Villanueva-Perez, P1
Bakoyiannis, C; Damaskos, C; Georgopoulos, S; Liakakos, T; Moris, D; Patelis, N; Perrea, D; Schizas, D1
Boyer, MJ; Cooper, HA; Eguchi, S; Forrester, SJ; Hashimoto, T; Kawai, T; Kobayashi, T; Kwok, HF; Obama, T; Preston, KJ; Rizzo, V; Scalia, R; Takayanagi, T; Tsuji, T1
Blanco, VM; Blomkalns, AL; Cassis, LA; Chatterjee, T; Daugherty, A; Fu, X; Fulton, DJ; Gavrila, D; Hazen, SL; Huo, Y; Kim, HW; Lindower, PD; McCormick, ML; Neltner, BS; Ogbi, M; Stansfield, BK; Thomas, M; Thompson, RW; Weintraub, NL; Weiss, RM1
Angelov, SN; Dichek, DA; Zhu, J1
Alsiraj, Y; Blalock, E; Cassis, LA; Daugherty, A; Fleenor, B; Thatcher, SE1
Akerman, AW; Barrs, RW; Grespin, RT; Ikonomidis, JS; Jones, JA; LaRue, RAC; McDonald, LT; Mukherjee, R; Ruddy, JM; Stroud, RE1
Bleackley, RC; Bohunek, L; Bozin, T; Granville, DJ; Järvinen, TAH; McManus, BM; Merkulova, Y; Oram, C; Ruoslahti, E; Russo, V; Santacruz, S; Seidman, MA; Sellers, SL; Shen, Y; Tauh, K; Turner, C; Wu, Z; Zeglinski, MR; Zeng, H; Zhao, H1
Blaize, AN; Chang, MS; Ejendal, KFK; Goergen, CJ; Gorman, S; Kinzer-Ursem, TL; Phillips, EH; Qureshi, HJ1
Chai, H; Chen, W; Chen, X; Huang, F; Su, C; Tao, Z; Xu, Y1
Bianco, R; Brown, BA; George, SJ; Johnson, JL; Lyon, CA; Simmonds, SJ; Smith, FCT; Wadey, KS; Williams, H1
Damen, FW; Goergen, CJ; Soepriatna, AH; Vlachos, PP1
Bai, WW; Cheng, W; Liang, ES; Liu, X; Yang, RX; Zhao, YX1
Al-Omran, M; Plant, PJ; Quan, A; Ramadan, A; Singh, KK; Teoh, H; Verma, S1
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Weintraub, NL1
Bai, L; Beckers, L; Biessen, EA; Cleutjens, K; Daemen, MJ; Heeneman, S; Herías, MV; Lutgens, E; Lutgens, SP; Saftig, P; Wijnands, E1
Aravindhan, K; Bernard, RE; Gough, PJ; Jucker, BM; Karr, HW; Mirabile, RC; Olzinski, AR; Turner, GH; Willette, RN1
Campbell, JH; Cullen, B; Daugherty, A; Golledge, J; Moran, CS; Norman, PE; Rush, C; Secomb, E; Wood, F1
Allard, MF; Ang, LS; Boivin, WA; Chamberlain, CM; Cooper, DM; Folkesson, M; Granville, DJ; Hendel, A; McManus, BM; Swedenborg, J; Williams, SJ; Zhao, H1
Ahluwalia, N; Anderson, TJ; Gerszten, RE; Hardy, GJ; Kristo, F; Lin, AY; Passeri, J; Scherrer-Crosbie, M; Sinha, S1
Kato, K; Lengfeld, J; Liu, B; Morgan, S; Yamanouchi, D; Zhang, F1
Ait-Oufella, H; Bonnin, P; Combadière, C; Herbin, O; Huang, J; Johnson, JL; Mallat, Z; Offenstadt, G; Ramkhelawon, B; Rénia, L; Taleb, S; Tedgui, A; Tharaux, PL; Wang, Y1
Gopal, K; Jahan, P; Kumar, K; Kumar, MJ; Nandini, R1
Hashimoto, T; Kanematsu, M; Kanematsu, Y; Kurihara, C; Liang, EI; Makino, H; Nuki, Y; Tsou, TL1
Aktas, H; Bronson, RT; Chen, T; Halperin, JA; Hu, W; Qin, X; Shahsafaei, A; Shi, GP; Wu, G1
Batifoulier-Yiannikouris, F; Cassis, LA; Daugherty, A; Police, SB; Putnam, K; Thatcher, S1
Chisolm, GM; Eagleton, MJ; Graham, LM; Liao, M; Parine, B; Xu, J1
Cassis, LA; Charnigo, R; Daugherty, A; Kristo, F; Lu, H; Rateri, DL; Uchida, HA1
Choke, E; Cockerill, GW; Dawson, J; Howe, F; Loftus, IM; Thompson, MM; Wilson, WR1
Libby, P; Lopez-Ilasaca, M; Macfarlane, L; Schulte, S; Shi, GP; Sukhova, GK; Sun, C; Sun, J1
Asagami, T; Dalman, RL; Dua, MM; Miyama, N; Schultz, GM; Sho, E; Sho, M; Yeung, JJ1
Cullen, B; Golledge, J; Moran, C; Rush, C1
Bailey, W; Boyanovsky, BB; Daugherty, A; de Beer, FC; Forrest, K; Gelb, MH; Howatt, DA; Shridas, P; Webb, NR; Zack, M1
Barr, KN; Choi, G; Connolly, AJ; Dalman, RL; Eastham-Anderson, JR; Goergen, CJ; Greve, JM; Hedehus, M; Huynh, DT; Taylor, CA; Tsao, PS1
Berges, A; Lebrun, S; Lietz, M; Stolle, K; Wallerath, T1
Azuma, J; Barr, KN; Connolly, AJ; Dalman, RL; Goergen, CJ; Gogineni, A; Greve, JM; Grewall, A; Kallop, DY; Magdefessel, L; Taylor, CA; Tsao, PS; Weimer, RM1
Bruemmer, D; Cohn, D; Daugherty, A; Findeisen, HM; Gizard, F; Heywood, EB; Howatt, DA; Jones, KL; Lovett, DH; Zhao, Y1
Fukuda, D; Libby, P; Rocha, VZ; Shi, GP; Shimizu, K; Shvartz, E; Sukhova, G; Tang, EH; Zheng, C1
Gerszten, RE; Keliher, E; Leuschner, F; Marinelli, B; Nahrendorf, M; Pittet, MJ; Robbins, CS; Swirski, FK; Weissleder, R1
Dong, XR; Hoglund, VJ; Majesky, MW1
Bi, H; Chen, WA; Daugherty, A; Hong, B; Luo, Y; Wang, JA; Wang, Y; Xie, X; Zhang, S1
Gleason, RL; Joseph, G; Maiellaro-Rafferty, K; Taylor, WR; Wan, W; Weiss, D1
Antiga, L; De Backer, J; De Santis, G; Loeys, B; Renard, M; Segers, P; Staelens, S; Trachet, B1
Azuma, J; Dalman, RL; Deng, A; Dyer, JS; Hsu, M; Maegdefessel, L; Spin, JM; Tedesco, MM; Tsao, PS1
Cassis, LA; Charnigo, R; Daugherty, A; Howatt, DA; Moorleghen, JJ; Rateri, DL1
Bi, H; Daugherty, A; Wang, JA; Wang, Y; Xie, X; Xu, Y; Zhang, G; Zhang, S1
Cassis, LA; Daugherty, A; Lu, H1
Cassis, LA; Daugherty, A; Poduri, A; Subramanian, V; Uchida, HA1
Inoue, T; Kikumoto, Y; Makino, H; Sugiyama, H; Takiue, K; Uchida, HA1
Abraham, T; Ang, LS; Bleackley, RC; Boivin, WA; Carmine-Simmen, K; Granville, DJ; McManus, BM; Williams, SJ; Zhao, H1
Arsenescu, R; Arsenescu, V; Baker, N; Cassis, LA; Karounos, M; Parulkar, M; Zhang, X1
Cassis, LA; Curtiss, LK; Daugherty, A; Howatt, DA; Lu, H; Moore, KJ; Owens, AP; Rateri, DL; Tobias, PS1
Balakrishnan, A; Howatt, DA; Ijaz, T; Moorleghen, JJ; Subramanian, V; Uchida, HA1
Cai, H; Chalupsky, K; Chen, P; Galis, Z; Gao, L; Nguyen, A; Siu, KL; Weintraub, NL1
Cardenas, JC; Church, FC; Rein, CM1
Cassis, LA; Charnigo, R; Daugherty, A; Howatt, DA; Lu, H; Moorleghen, JJ; Subramanian, V; Wang, S1
Angsana, J; Chaikof, EL; Ford, ML; Haller, CA; Park, PW; Smith, SV; Wen, J; Xiao, J1
Azhar, M; Fouts, M; Haskett, D; Larson, D; Speicher, E; Utzinger, U; Vande Geest, J1
Bruemmer, D; Daugherty, A; Lu, H; Rateri, DL1
Azuma, J; Chin, JT; Dalman, RL; Deng, A; Leeper, NJ; Maegdefessel, L; McConnell, MV; Merk, DR; Raaz, U; Raiesdana, A; Schoelmerich, AM; Spin, JM; Toh, R; Tsao, PS1
Caligiuri, G; Clement, M; Fornasa, G; Gaston, AT; Groyer, E; Guedj, K; Kaveri, SV; Khallou-Laschet, J; Michel, JB; Morvan, M; Nicoletti, A; Tedgui, A1
Azuma, J; Dalman, RL; Deng, A; Leeper, NJ; Maegdefessel, L; McConnell, MV; Merk, DR; Raaz, U; Raiesdana, A; Schoelmerich, AM; Spin, JM; Toh, R; Tsao, PS1
Liu, L; Shi, GP1
Fazio, S; Guo, Z; Kon, V; Linton, MF; Perati, PR; Prins, PA; Ramesh, A; Sampson, UK1
Fang, F; Li, Y; Liu, N; Ma, G; Sheng, Z; Teng, GJ; Wang, Y; Wen, S; Yao, Y; Zhang, Y1
Eagleton, MJ; Ehrman, B; Graham, LM; Xu, J1
Asada, Y; Endo, GJ; Hatakeyama, K; Imamura, T; Kitamura, K; Matsuyama, M; Nagamachi, S; Nishimura, M; Onitsuka, T; Sakamoto, S; Sato, Y; Sekita, Y; Tsuruda, T; Yoshimura, K1
Bruemmer, D; Cassis, LA; Charnigo, R; Daugherty, A; Rateri, DL; Thatcher, SE; Zhang, X1
Lee, J; Liang, B; Viollet, B; Wang, S; Xia, L; Zhang, C; Zhang, M; Zhang, Y; Zhu, H; Zou, MH1
Aoki, H; Fujita, T; Ichikawa, Y; Ishikawa, Y; Ishiwata, R; Jin, H; Jin, MH; Katayama, Y; Kato, Y; Kumagaya, S; Masuda, M; Minamisawa, S; Okumura, S; Sato, M; Sugimoto, Y; Suzuki, O; Suzuki, S; Yokoyama, U1
Brown, PM; Cao, RY; Funk, CD; Li, X; Maruyama, T; Song, H; St Amand, T; Wang, CP; Yoon, SH; Zelt, DT1
Golledge, J; Krishna, SM; Moxon, JV; Norman, PE; Rush, C; Seto, SW; Walker, PJ1
Bailey, W; Boyanovsky, BB; Dixon, L; Shridas, P; Webb, NR1
Chen, H; Liu, L; Shi, GP; Shi, MA; Sukhova, GK; Sun, J; Zhang, J1
Cao, X; Du, J; Guo, J; Li, H; Pan, L; Qin, Y; Shi, GP; Tang, C; Zhang, H; Zhang, Y1
Csiszar, K; Fong, SF; Joseph, G; O'Donnell, RE; Rafferty, K; Remus, EW; Taylor, WR; Weiss, D1
Beeri, R; Berlatzky, Y; Bulut, A; Gavish, L; Gavish, LY; Gertz, SD; Gilon, D; Harlev, M; Reissman, P; Rubinstein, C1
Feng, J; Hu, J; Huang, Y; Kong, W; Liu, B; Liu, Z; Luo, H; Ma, K; Wang, X; Xie, J; Xu, Q; Zhan, S; Zhang, L; Zheng, J; Zhu, Y1
Gitlin, JM; Loftin, CD; Mukherjee, K1
Asano, T; Fujita, T; Gao, J; Hasegawa, Y; Imai, J; Ishigaki, Y; Kaneko, K; Katagiri, H; Ogihara, T; Oka, Y; Saito, T; Shimosawa, T; Uno, K; Yamada, T1
Baxter, BT; Charolidi, N; Cockerill, GW; Gaze, D; Laing, K; Meisinger, T; Petrova, S; Pirianov, G; Shoreim, A; Torsney, E; Xiong, W1
Cassis, LA; Daugherty, A; Howatt, DA; Lu, H; Moorleghen, JJ; Rateri, DL; Xie, X1
Jackson, CL; Rodgers, KJ1
Beceiro, S; Cheng, J; Garg, V; Guggilam, A; Hans, CP; Huang, N; Koenig, SN; Kuivaniemi, H; Partida-Sánchez, S1
Baldwin, TA; Basu, R; Das, SK; Fan, D; Kandalam, V; Kassiri, Z; Lee, J; Oudit, GY; Wang, X1
Hao, S; Kolodgie, FD; Mizrahi, B; Nguyen, BT; Ozaki, CK; Savion, N; Schneiderman, J; Tao, M; Virmani, R; Yu, P1
Du, J; Jia, L; Liu, O; Liu, X; Qin, Y; Wang, X; Wang, Y; Zhang, H1
Dalman, RL; Fujimura, N; Glover, KJ; Hu, X; Iida, Y; Schultz, JR; Tanaka, H; Turner, CR; Wang, W; Xu, B; Xuan, H1
Dalloz, M; Esposito, B; Mallat, Z; Pérez, N; Ponnuswamy, P; Romain, M; Taleb, S; Tedgui, A; Wang, Y; Yoshimura, A1
Golledge, J; Jose, RJ; Körner, H; Moran, CS; Moxon, JV; Norman, PE; Roomberg, A; Rush, C1
Dole, W; Martin-McNulty, B; Rutledge, JC; Sullivan, ME; Tham, DM; Vergona, R; Wang, YX; Wilson, DW1
Athanassious, CN; Da Cunha, V; Martin-McNulty, B; Powers, AF; Rutledge, JC; Sullivan, ME; Tham, DM; Wang, YX; Wilson, DW1
Carmeliet, P; Deng, GG; Dole, WP; Freay, A; Halks-Miller, M; Loskutoff, DJ; Martin-McNulty, B; Sukovich, DA; Thinnes, T; Wang, YX1
Cassis, LA; Daugherty, A; Manning, MW3
da Cunha, V; Deng, GG; Ho, JJ; Martin-McNulty, B; Rutledge, JC; Sullivan, ME; Tham, DM; Vergona, R; Wang, YX; Wilson, DW1
Cassis, LA; Daugherty, A; Lodder, RA; Manning, MW; Urbas, A1
Arias-Magallona, S; Blaschke, F; Bruemmer, D; Collins, AR; Fishbein, MC; Graf, K; Hsueh, WA; Kintscher, U; Law, RE; Noh, G; Territo, M; Wang, W1
Cassis, LA; Daugherty, A1
Cassis, LA; D'Souza, SS; Daugherty, A; Henriques, TA; Huang, J1
Cassis, L; Daugherty, A3
Charo, IF; Egashira, K; Hiasa, K; Ihara, Y; Ishibashi, M; Kura, S; Ohtani, K; Sunagawa, K; Takeshita, A; Tsuzuki, T; Zhao, Q1
Cassis, LA; Daugherty, A; Helton, MJ; Howatt, DA; King, VL1
da Cunha, V; Deng, GD; Dole, WP; Feng, Q; Halks-Miller, M; Johns, A; Kauser, K; Light, DR; Lu, X; Mahmoudi, M; Martin-McNulty, B; Schirm, S; Schroeder, M; Subramanyam, B; Tseng, JL; Vincelette, J; Wang, YX1
Cassis, LA; Daugherty, A; Dellsperger, KC; Gavrila, D; Li, WG; McCormick, ML; Miller, FJ; Oberley, LW; Thomas, M; Weintraub, NL1
Golledge, J; Karan, M; Ketheesan, N; McCann, M; Moran, CS; Norman, P1
Gitlin, JM; King, VL; Loftin, CD; Trivedi, DB1
Bishop-Bailey, D; Mitchell, JA; Warner, TD1
Cassis, LA; Daugherty, A; Dellsperger, KC; Gavrila, D; McCormick, ML; Miller, FJ; Thomas, M; Weintraub, NL1
Barisione, C; Charnigo, R; Daugherty, A; Howatt, DA; Moorleghen, JJ; Rateri, DL1
Gitlin, JM; Langenbach, R; Loftin, CD; Trivedi, DB1
Cassis, LA; Daugherty, A; Rateri, DL1
Croze, E; Fitch, RM; Sullivan, ME; Velichko, S; Vergona, R; Vincelette, J; Wang, YX; Zhang, LN1
Fukumoto, H; Furubayashi, K; Ibaraki, T; Jin, D; Katsumata, T; Miyazaki, M; Muramatsu, M; Nishimoto, M; Takai, S1
Adams, MA; Cao, RY; Funk, CD; Habenicht, AJ1
Dear, AE; Dousha, LF; Gaspari, TA; Liu, HB; Vinh, A; Widdop, RE1
Deng, GG; Dole, WP; Gu, JM; Halks-Miller, M; Kauser, K; Liu, P; Qian, HS; Sullivan, ME; Vergona, R1
FitzGerald, GA; Lawson, JA; Lee, E; Puré, E; Rader, DJ; Ricciotti, E; Song, W; Wang, M1
Cassis, LA; Daugherty, A; Henriques, T; Yiannikouris, FB; Zhang, X1
Cassis, LA; Daugherty, A; Lu, H; Rateri, DL1
Berk, BC; Haendeler, J; Sottile, J1
Deng, GG; Dole, WP; Freay, AD; Halks-Miller, M; Li, WW; Martin-McNulty, B; Morser, J; Sukovich, DA; Sullivan, ME; Vergona, R; Wang, YX1

Reviews

17 review(s) available for angiotensin ii and Aortic Aneurysm, Abdominal

ArticleYear
Role of Serum Amyloid A in Abdominal Aortic Aneurysm and Related Cardiovascular Diseases.
    Biomolecules, 2021, 12-15, Volume: 11, Issue:12

    Topics: Angiotensin II; Aortic Aneurysm, Abdominal; Biomarkers; Cardiovascular Diseases; Gene Expression Regulation; Humans; Serum Amyloid A Protein

2021
Twenty Years of Studying AngII (Angiotensin II)-Induced Abdominal Aortic Pathologies in Mice: Continuing Questions and Challenges to Provide Insight Into the Human Disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2022, Volume: 42, Issue:3

    Topics: Age Factors; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Female; Heart Disease Risk Factors; Humans; Hypercholesterolemia; Male; Mice; Mice, Transgenic; Models, Cardiovascular; Receptors, Angiotensin; Sex Factors

2022
Animal models in the research of abdominal aortic aneurysms development.
    Physiological research, 2017, 12-20, Volume: 66, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Female; Genetic Predisposition to Disease; Hemodynamics; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phenotype; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sus scrofa; Vascular Remodeling

2017
Pathogenic and Therapeutic Significance of Angiotensin II Type I Receptor in Abdominal Aortic Aneurysms.
    Current drug targets, 2018, Volume: 19, Issue:11

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Clinical Trials as Topic; Disease Models, Animal; Disease Progression; Humans; Receptor, Angiotensin, Type 1; Telmisartan; Valsartan

2018
Dissecting abdominal aortic aneurysm in Angiotensin II-infused mice: the importance of imaging.
    Current pharmaceutical design, 2015, Volume: 21, Issue:28

    Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Disease Models, Animal; Hematoma; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Mice; Tomography, X-Ray Computed

2015
Monocytes, Macrophages and Other Inflammatory Mediators of Abdominal Aortic Aneurysm.
    Current pharmaceutical design, 2015, Volume: 21, Issue:28

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Inflammation Mediators; Macrophages; Mice; Monocytes; Spleen

2015
Angiotensin II and Abdominal Aortic Aneurysms: An update.
    Current pharmaceutical design, 2015, Volume: 21, Issue:28

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Humans; Mice; Molecular Targeted Therapy

2015
Incidence, severity, mortality, and confounding factors for dissecting AAA detection in angiotensin II-infused mice: a meta-analysis.
    Cardiovascular research, 2015, Oct-01, Volume: 108, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Disease Models, Animal; Female; Incidence; Male; Mice; Mice, Inbred C57BL

2015
Atherosclerosis and aortic aneurysm - is inflammation a common denominator?
    The FEBS journal, 2016, Volume: 283, Issue:9

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Cytokines; Diet, Western; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Risk Factors; Sedentary Behavior; Smoking

2016
Complex pathologies of angiotensin II-induced abdominal aortic aneurysms.
    Journal of Zhejiang University. Science. B, 2011, Volume: 12, Issue:8

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Connective Tissue; Disease Models, Animal; Disease Progression; Female; Humans; Hypercholesterolemia; Male; Mice; Peptides; Renin-Angiotensin System; Time Factors

2011
Relevance of angiotensin II-induced aortic pathologies in mice to human aortic aneurysms.
    Annals of the New York Academy of Sciences, 2011, Volume: 1245

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Disease Models, Animal; Humans; Mice; Renin-Angiotensin System; Species Specificity

2011
Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II-induced abdominal aortic aneurysm in mice.
    Circulation research, 2012, Oct-26, Volume: 111, Issue:10

    Topics: Adventitia; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Chemokine CCL2; Disease Models, Animal; Female; Fibroblasts; Humans; Hyperhomocysteinemia; Incidence; Interleukin-6; Male; Mice; Mice, Mutant Strains; Middle Aged; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; Risk Factors; Signal Transduction; Smad2 Protein; Smad3 Protein; Vasculitis; Vasoconstrictor Agents

2012
Mouse models of abdominal aortic aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Calcium Chloride; Cholesterol; Disease Models, Animal; Extracellular Matrix Proteins; Female; Genetic Engineering; Genetic Predisposition to Disease; Humans; Hyperlipidemias; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Knockout; Mice, Mutant Strains; Models, Animal; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pancreatic Elastase; Protease Inhibitors; Receptors, LDL; Renin; Species Specificity

2004
Angiotensin II-mediated development of vascular diseases.
    Trends in cardiovascular medicine, 2004, Volume: 14, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Arteriosclerosis; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Humans; Hyperlipidemias; Macrophages; Vascular Diseases

2004
Angiotensin II and abdominal aortic aneurysms.
    Current hypertension reports, 2004, Volume: 6, Issue:6

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Aneurysm, Abdominal; Humans; Mice

2004
Role of the renin-angiotensin system in the development of abdominal aortic aneurysms in animals and humans.
    Annals of the New York Academy of Sciences, 2006, Volume: 1085

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Humans; Models, Biological; Renin-Angiotensin System

2006
The role of the renin-angiotensin system in aortic aneurysmal diseases.
    Current hypertension reports, 2008, Volume: 10, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Humans; Mice; Renin-Angiotensin System; Risk Factors

2008

Other Studies

422 other study(ies) available for angiotensin ii and Aortic Aneurysm, Abdominal

ArticleYear
Defective autophagy in vascular smooth muscle cells enhances the healing of abdominal aortic aneurysm.
    Physiological reports, 2021, Volume: 9, Issue:17

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Autophagy; Cells, Cultured; Infusion Pumps, Implantable; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle

2021
Circular RNA Cdyl promotes abdominal aortic aneurysm formation by inducing M1 macrophage polarization and M1-type inflammation.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2022, 02-02, Volume: 30, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; RNA, Circular

2022
Interferon-stimulated gene 15 pathway is a novel mediator of endothelial dysfunction and aneurysms development in angiotensin II infused mice through increased oxidative stress.
    Cardiovascular research, 2022, 12-29, Volume: 118, Issue:16

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Carotid Intima-Media Thickness; Elastin; Humans; Hypertension; Inflammation; Interferons; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species

2022
miR-10b promotes aortic aneurysm formation and aortic rupture in angiotensin II-induced ApoE-deficient mice.
    Vascular pharmacology, 2021, Volume: 141

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; MicroRNAs

2021
Rosmarinic Acid Suppresses Abdominal Aortic Aneurysm Progression in Apolipoprotein E-deficient Mice.
    Planta medica, 2022, Volume: 88, Issue:11

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Cinnamates; Depsides; Disease Models, Animal; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Rosmarinic Acid

2022
Knockdown of long noncoding RNA GAS5 reduces vascular smooth muscle cell apoptosis by inactivating EZH2-mediated RIG-I signaling pathway in abdominal aortic aneurysm.
    Journal of translational medicine, 2021, 11-15, Volume: 19, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; Signal Transduction

2021
Identification of Circ-FNDC3B, an Overexpressed circRNA in Abdominal Aortic Aneurysm, as a Regulator of Vascular Smooth Muscle Cells.
    International heart journal, 2021, Nov-30, Volume: 62, Issue:6

    Topics: ADAM10 Protein; Angiotensin II; Aortic Aneurysm, Abdominal; Case-Control Studies; Fibronectins; Gene Silencing; Humans; MicroRNAs; Myocytes, Smooth Muscle; Oxidative Stress; RNA, Circular

2021
The tyrosine kinase inhibitor Bosutinib does not inhibit angiotensin II-induced abdominal aortic aneurysm: Validation of the importance of PDGFR and c-Kit tyrosine kinases by Imatinib.
    Atherosclerosis, 2022, Volume: 340

    Topics: Angiotensin II; Aniline Compounds; Aortic Aneurysm, Abdominal; Humans; Imatinib Mesylate; Nitriles; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Quinolines

2022
Platelet protects angiotensin II-driven abdominal aortic aneurysm formation through inhibition of inflammation.
    Experimental gerontology, 2022, Volume: 159

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Platelets; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout

2022
Role of prostaglandin D2 receptors in the pathogenesis of abdominal aortic aneurysm formation.
    Clinical science (London, England : 1979), 2022, 03-18, Volume: 136, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Male; Mice; Receptors, Immunologic; Receptors, Prostaglandin

2022
Trimethylamine N-Oxide Promotes Abdominal Aortic Aneurysm Formation by Aggravating Aortic Smooth Muscle Cell Senescence in Mice.
    Journal of cardiovascular translational research, 2022, Volume: 15, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Disease Models, Animal; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle

2022
Tolvaptan reduces angiotensin II-induced experimental abdominal aortic aneurysm and dissection.
    Vascular pharmacology, 2022, Volume: 144

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Tolvaptan

2022
Interleukin-22 Deficiency Reduces Angiotensin II-Induced Aortic Dissection and Abdominal Aortic Aneurysm in ApoE-/- Mice.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Apolipoproteins E; Interleukin-22; Interleukins; Mice

2022
Adipocyte-Derived Serum Amyloid A Promotes Angiotensin II-Induced Abdominal Aortic Aneurysms in Obese C57BL/6J Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2022, Volume: 42, Issue:5

    Topics: Adipocytes; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Doxycycline; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Obesity; Serum Amyloid A Protein

2022
Lipid phosphate phosphatase 3 in smooth muscle cells regulates angiotensin II-induced abdominal aortic aneurysm formation.
    Scientific reports, 2022, 04-05, Volume: 12, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Phosphatidate Phosphatase

2022
Cysteine-rich protein 2 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in mice.
    Journal of biomedical science, 2022, Apr-12, Volume: 29, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Cysteine; Disease Models, Animal; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle

2022
Calcitriol Supplementation Protects Against Apoptosis and Alleviates the Severity of Abdominal Aortic Aneurysm Induced by Angiotensin II and Anti-TGFβ.
    Journal of cardiovascular translational research, 2022, Volume: 15, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Calcitriol; Dietary Supplements; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Transforming Growth Factor beta

2022
Single-Cell RNA Sequencing Technology Revealed the Pivotal Role of Fibroblast Heterogeneity in Angiotensin II-Induced Abdominal Aortic Aneurysms.
    DNA and cell biology, 2022, Volume: 41, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Endothelial Cells; Fibroblasts; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Sequence Analysis, RNA

2022
An intersegmental single-cell profile reveals aortic heterogeneity and identifies a novel Malat1
    Signal transduction and targeted therapy, 2022, 04-27, Volume: 7, Issue:1

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle

2022
Nuclear receptor Nur77 protects against oxidative stress by maintaining mitochondrial homeostasis via regulating mitochondrial fission and mitophagy in smooth muscle cell.
    Journal of molecular and cellular cardiology, 2022, Volume: 170

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Homeostasis; Mice; Mitochondrial Dynamics; Mitophagy; Myocytes, Smooth Muscle; Nuclear Receptor Subfamily 4, Group A, Member 1; Oxidative Stress

2022
Statin therapy protects against abdominal aortic aneurysms by inducing the accumulation of regulatory T cells in ApoE
    Journal of molecular medicine (Berlin, Germany), 2022, Volume: 100, Issue:7

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Dysbiosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Knockout; Simvastatin; T-Lymphocytes, Regulatory

2022
Metabolomic Profiling of Angiotensin-II-Induced Abdominal Aortic Aneurysm in Ldlr
    International journal of molecular sciences, 2022, Jun-07, Volume: 23, Issue:12

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Energy Metabolism; Glutamine; Glycine; Hypercholesterolemia; Hyperlipidemias; Lipids; Metabolomics; Mice; Mice, Inbred C57BL; Nitric Oxide; Receptors, LDL

2022
Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2.
    Circulation, 2022, 11-22, Volume: 146, Issue:21

    Topics: Aconitate Hydratase; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Citric Acid Cycle; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Receptor Subfamily 1, Group D, Member 1

2022
[Role of nicotinamide phosphoribosyltransferase in delaying smooth muscle cell senescence and protecting abdominal aortic aneurysm].
    Zhonghua wei zhong bing ji jiu yi xue, 2022, Volume: 34, Issue:6

    Topics: Angiotensin II; Aortic Aneurysm, Abdominal; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nicotinamide Phosphoribosyltransferase

2022
Drug Treatment by Central Venous Catheter in a Mouse Model of Angiotensin II Induced Abdominal Aortic Aneurysm and Monitoring by 3D Ultrasound.
    Journal of visualized experiments : JoVE, 2022, 08-04, Issue:186

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Catheterization; Central Venous Catheters; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Ultrasonography

2022
Phosphodiesterase 4D contributes to angiotensin II-induced abdominal aortic aneurysm through smooth muscle cell apoptosis.
    Experimental & molecular medicine, 2022, Volume: 54, Issue:8

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Mice; Mice, Knockout; Myocytes, Smooth Muscle

2022
Edaravone Attenuated Angiotensin II-Induced Atherosclerosis and Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice.
    Biomolecules, 2022, 08-14, Volume: 12, Issue:8

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Atherosclerosis; Edaravone; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL; RNA, Messenger

2022
BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis.
    The Journal of clinical investigation, 2022, 11-01, Volume: 132, Issue:21

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Epigenesis, Genetic; Homeostasis; Humans; Inflammation; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle

2022
The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice-Brief Report.
    Arteriosclerosis, thrombosis, and vascular biology, 2022, Volume: 42, Issue:10

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Cholesterol; Elastin; Matrix Metalloproteinase 14; Mice; Netrin-1; Proprotein Convertase 9; Subtilisins

2022
Disparate biomechanical properties of the aorta in non-aneurysmal and aneurysmal mice treated with angiotensin II.
    Physiological reports, 2022, Volume: 10, Issue:18

    Topics: Adrenergic Agents; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Collagen; Elastin; Mice; Mice, Inbred C57BL; Pulse Wave Analysis

2022
Overexpressed DDX3x promotes abdominal aortic aneurysm formation and activates AKT in ApoE knockout mice.
    Biochemical and biophysical research communications, 2022, 12-17, Volume: 634

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; DEAD-box RNA Helicases; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Proto-Oncogene Proteins c-akt

2022
LOX-1 deficiency increases ruptured abdominal aortic aneurysm via thinning of adventitial collagen.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2023, Volume: 46, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atherosclerosis; Collagen; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Plaque, Atherosclerotic; Scavenger Receptors, Class E

2023
Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.
    Redox biology, 2022, Volume: 58

    Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Folic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Nifedipine

2022
ADAR1 Non-Editing Function in Macrophage Activation and Abdominal Aortic Aneurysm.
    Circulation research, 2023, 02-17, Volume: 132, Issue:4

    Topics: Adenosine Deaminase; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; I-kappa B Kinase; Inflammation; Macrophage Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; NF-kappa B; RNA-Binding Proteins

2023
Interleukin-38 suppresses abdominal aortic aneurysm formation in mice by regulating macrophages in an IL1RL2-p38 pathway-dependent manner.
    Physiological reports, 2023, Volume: 11, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Interleukins; Macrophages; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Receptors, Interleukin

2023
Hyperuricemia exacerbates abdominal aortic aneurysm formation through the URAT1/ERK/MMP-9 signaling pathway.
    BMC cardiovascular disorders, 2023, 01-30, Volume: 23, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Hyperuricemia; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mice; Reactive Oxygen Species; Retrospective Studies; Signal Transduction; Uric Acid

2023
Smooth muscle angiotensin II type 1A receptor is required for abdominal aortic aneurysm formation induced by angiotensin II plus β-aminopropionitrile.
    Journal of molecular and cellular cardiology, 2023, Volume: 176

    Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Muscle, Smooth; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1

2023
Netrin-1 Monoclonal Antibody-Functionalized Nanoparticle Loaded with Metformin Prevents the Progression of Abdominal Aortic Aneurysms.
    International journal of nanomedicine, 2023, Volume: 18

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Nanoparticles; Netrin-1; Phenotype

2023
Divergent Roles of Matrix Metalloproteinase 12 in Abdominal Aortic Aneurysms.
    Circulation research, 2023, 02-17, Volume: 132, Issue:4

    Topics: Angiotensin II; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Humans; Matrix Metalloproteinase 12; Matrix Metalloproteinase 9

2023
RelB represses miR-193a-5p expression to promote the phenotypic transformation of vascular smooth muscle cells in aortic aneurysm.
    Biochimica et biophysica acta. Gene regulatory mechanisms, 2023, Volume: 1866, Issue:2

    Topics: Adult; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cell Movement; Cell Proliferation; Cyclin D1; Cyclin E; Down-Regulation; Female; Humans; Male; Mice; MicroRNAs; Muscle, Smooth, Vascular; Receptors, CXCR4; Transcription Factor RelB

2023
Targeting mitochondrial stress with Szeto-Schiller 31 prevents experimental abdominal aortic aneurysm: Crosstalk with endoplasmic reticulum stress.
    British journal of pharmacology, 2023, Volume: 180, Issue:17

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Endoplasmic Reticulum Stress; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Reactive Oxygen Species

2023
CARMA3 Deficiency Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysm Development Interacting Between Endoplasmic Reticulum and Mitochondria.
    The Canadian journal of cardiology, 2023, Volume: 39, Issue:10

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; CARD Signaling Adaptor Proteins; Disease Models, Animal; Endoplasmic Reticulum; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria

2023
Taxifolin ameliorates abdominal aortic aneurysm by preventing inflammation and apoptosis and extracellular matrix degradation via inactivating TLR4/NF-κB axis.
    International immunopharmacology, 2023, Volume: 119

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Disease Models, Animal; Extracellular Matrix; Humans; Inflammation; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; NF-kappa B; Toll-Like Receptor 4

2023
Tributyrin Intake Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm in
    International journal of molecular sciences, 2023, Apr-28, Volume: 24, Issue:9

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Elastin; Epigenesis, Genetic; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout

2023
Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1.
    Biochemical pharmacology, 2023, Volume: 213

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Scavenger

2023
ANGPTL8 deletion attenuates abdominal aortic aneurysm formation in ApoE-/- mice.
    Clinical science (London, England : 1979), 2023, 06-28, Volume: 137, Issue:12

    Topics: Angiopoietin-Like Protein 8; Angiotensin II; Animals; Aorta; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Peptide Hormones

2023
The Histone Methyltransferase SETDB2 Modulates Tissue Inhibitors of Metalloproteinase-Matrix Metalloproteinase Activity During Abdominal Aortic Aneurysm Development.
    Annals of surgery, 2023, 09-01, Volume: 278, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Histone Methyltransferases; Histones; Humans; Janus Kinases; Lysine; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Tissue Inhibitor of Metalloproteinase-3

2023
Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms.
    Biomolecules, 2023, 05-28, Volume: 13, Issue:6

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Body Weight; Disease Models, Animal; Disulfiram; Gasdermins; Male; Mice; Mice, Inbred C57BL

2023
Plasma Lipidomics Analysis Reveals the Potential Role of Lysophosphatidylcholines in Abdominal Aortic Aneurysm Progression and Formation.
    International journal of molecular sciences, 2023, Jun-16, Volume: 24, Issue:12

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomarkers; Disease Models, Animal; Lipidomics; Lysophosphatidylcholines; Mice; Mice, Inbred C57BL

2023
CD147 monoclonal antibody attenuates abdominal aortic aneurysm formation in angiotensin II-Infused apoE
    International immunopharmacology, 2023, Volume: 122

    Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Proteomics

2023
Vascular Ultrasound for In Vivo Assessment of Arterial Pathologies in a Murine Model of Atherosclerosis and Aortic Aneurysm.
    International journal of molecular sciences, 2023, Oct-17, Volume: 24, Issue:20

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atherosclerosis; Carotid Intima-Media Thickness; Collagen; Disease Models, Animal; Mice; Mice, Inbred C57BL

2023
Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm.
    Bioscience reports, 2023, Nov-30, Volume: 43, Issue:11

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis Regulatory Proteins; Disease Models, Animal; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Reactive Oxygen Species

2023
Melanocortin-4 receptor in macrophages attenuated angiotensin II-induced abdominal aortic aneurysm in mice.
    Scientific reports, 2023, 11-13, Volume: 13, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Leptin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Obesity; Phosphatidylinositol 3-Kinases; Receptor, Melanocortin, Type 4

2023
Effect of Hydralazine on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Deficient Mice.
    International journal of molecular sciences, 2023, Nov-03, Volume: 24, Issue:21

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins; Apolipoproteins E; Apoptosis; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout

2023
Involvement of an IgE/Mast cell/B cell amplification loop in abdominal aortic aneurysm progression.
    PloS one, 2023, Volume: 18, Issue:12

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Immunoglobulin E; Interleukin-4; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE

2023
ATRQβ-001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms.
    Journal of the American Heart Association, 2019, 09-17, Volume: 8, Issue:18

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Calcium Phosphates; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteopontin; Random Allocation; Vaccines, Virus-Like Particle; Vasoconstrictor Agents

2019
Pharmacological inhibition of Notch signaling regresses pre-established abdominal aortic aneurysm.
    Scientific reports, 2019, 09-17, Volume: 9, Issue:1

    Topics: ADP-ribosyl Cyclase 1; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Cells, Cultured; Collagen; Cytokines; Dipeptides; Disease Models, Animal; Extracellular Matrix; Gene Expression Regulation; Humans; Male; Membrane Glycoproteins; Mice; Myocytes, Smooth Muscle; Receptors, Notch; Signal Transduction

2019
Up-regulated MCPIP1 in abdominal aortic aneurysm is associated with vascular smooth muscle cell apoptosis and MMPs production.
    Bioscience reports, 2019, 11-29, Volume: 39, Issue:11

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apoptosis; Cell Proliferation; Down-Regulation; Humans; Male; Matrix Metalloproteinases; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Rats; Rats, Sprague-Dawley; Ribonucleases; Signal Transduction; Transcription Factors; Transcriptional Activation; Up-Regulation

2019
Angiotensin-(1-7) mitigated angiotensin II-induced abdominal aortic aneurysms in apolipoprotein E-knockout mice.
    British journal of pharmacology, 2020, Volume: 177, Issue:8

    Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Peptide Fragments

2020
IL-27 receptor-regulated stress myelopoiesis drives abdominal aortic aneurysm development.
    Nature communications, 2019, 11-06, Volume: 10, Issue:1

    Topics: Aneurysm; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Cell Differentiation; Cytokines; Disease Models, Animal; Female; Hematopoietic Stem Cells; Interleukin-27; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Myeloid Cells; Myelopoiesis; Receptors, Interleukin; Signal Transduction

2019
Depletion of CD11c+ dendritic cells in apolipoprotein E-deficient mice limits angiotensin II-induced abdominal aortic aneurysm formation and growth.
    Clinical science (London, England : 1979), 2019, 11-15, Volume: 133, Issue:21

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; CD11 Antigens; Cholesterol; Dendritic Cells; Leukocyte Elastase; Lymphocyte Count; Male; Mice, Knockout, ApoE; Random Allocation; Vascular Remodeling

2019
Female Mice Exhibit Abdominal Aortic Aneurysm Protection in an Established Rupture Model.
    The Journal of surgical research, 2020, Volume: 247

    Topics: Administration, Oral; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Knockout, ApoE; Protective Factors; Sex Factors

2020
Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide.
    Cardiovascular research, 2020, 12-01, Volume: 116, Issue:14

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Male; Mice, Inbred C57BL; Mice, Knockout; NAD; Niacin; Niacinamide; Receptors, G-Protein-Coupled; Receptors, LDL; Signal Transduction; Sirtuin 1

2020
Imaging cellular activity and proliferation in the aortic wall.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021, Volume: 28, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cell Proliferation; Dideoxynucleosides; Disease Models, Animal; Fluorine Radioisotopes; Male; Mice; Mice, Knockout, ApoE; Positron Emission Tomography Computed Tomography; Reproducibility of Results; Time Factors

2021
Depletion of CD11c+ cell attenuates progression of abdominal aortic aneurysm.
    Clinical science (London, England : 1979), 2020, 01-17, Volume: 134, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Dendritic Cells; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout

2020
Pro-Renin Receptor Overexpression Promotes Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-Knockout Mice.
    Human gene therapy, 2020, Volume: 31, Issue:11-12

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Cytokines; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Macrophages; Male; Matrix Metalloproteinases; Mice; Mice, Knockout, ApoE; Myocytes, Smooth Muscle; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Signal Transduction; Vacuolar Proton-Translocating ATPases

2020
Alterations in gut microbiota of abdominal aortic aneurysm mice.
    BMC cardiovascular disorders, 2020, Jan-28, Volume: 20, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Bacteria; Disease Models, Animal; Dysbiosis; Feces; Gastrointestinal Microbiome; Intestines; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Ribotyping

2020
Targeting vascular smooth muscle cell dysfunction with xanthine derivative KMUP-3 inhibits abdominal aortic aneurysm in mice.
    Atherosclerosis, 2020, Volume: 297

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Apoptosis Regulatory Proteins; Cells, Cultured; Disease Models, Animal; Male; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Piperidines; Rats, Sprague-Dawley; Signal Transduction; Vascular Calcification; Xanthines

2020
AVE0991, a nonpeptide angiotensin-(1-7) mimic, inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice.
    Journal of molecular medicine (Berlin, Germany), 2020, Volume: 98, Issue:4

    Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Disease Models, Animal; Humans; Imidazoles; Immunohistochemistry; Lipids; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Molecular Mimicry; Myocytes, Smooth Muscle; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments

2020
A novel STAT3 inhibitor attenuates angiotensin II-induced abdominal aortic aneurysm progression in mice through modulating vascular inflammation and autophagy.
    Cell death & disease, 2020, 02-18, Volume: 11, Issue:2

    Topics: Aminosalicylic Acids; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Apoptosis; Autophagy; Autophagy-Related Proteins; Cells, Cultured; Disease Models, Animal; Janus Kinase 2; Male; Mice, Knockout, ApoE; NF-kappa B; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Vascular Remodeling

2020
Role of ADAM9 and miR-126 in the development of abdominal aortic aneurysm.
    Atherosclerosis, 2020, Volume: 297

    Topics: 3' Untranslated Regions; ADAM Proteins; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Binding Sites; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation, Enzymologic; Macrophages; Male; Membrane Proteins; Mice, Knockout, ApoE; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction

2020
Evaluation of a smart activatable MRI nanoprobe to target matrix metalloproteinases in the early-stages of abdominal aortic aneurysms.
    Nanomedicine : nanotechnology, biology, and medicine, 2020, Volume: 26

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Contrast Media; Disease Models, Animal; Ferric Compounds; Gene Expression Regulation; Humans; Magnetic Resonance Imaging; Matrix Metalloproteinases; Mice; Nanoparticles

2020
A Modified Murine Abdominal Aortic Aneurysm Rupture Model Using Elastase Perfusion and Angiotensin II Infusion.
    Annals of vascular surgery, 2020, Volume: 67

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Inflammation Mediators; Male; Mice, Inbred C57BL; Pancreatic Elastase; Time Factors; Vascular Remodeling

2020
Runx2 (Runt-Related Transcription Factor 2)-Mediated Microcalcification Is a Novel Pathological Characteristic and Potential Mediator of Abdominal Aortic Aneurysm.
    Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:5

    Topics: Adult; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Case-Control Studies; Core Binding Factor Alpha 1 Subunit; Dilatation, Pathologic; Disease Models, Animal; Durapatite; Female; Humans; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Middle Aged; Signal Transduction; Vascular Calcification; Vascular Remodeling

2020
MiR-144-5p limits experimental abdominal aortic aneurysm formation by mitigating M1 macrophage-associated inflammation: Suppression of TLR2 and OLR1.
    Journal of molecular and cellular cardiology, 2020, Volume: 143

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Line; Cell Plasticity; Disease Models, Animal; Disease Susceptibility; Gene Expression; Humans; Inflammation; Macrophage Activation; Macrophages; Mice; Mice, Knockout; MicroRNAs; RAW 264.7 Cells; RNA Interference; Scavenger Receptors, Class E; Toll-Like Receptor 2

2020
Factor XII blockade inhibits aortic dilatation in angiotensin II-infused apolipoprotein E-deficient mice.
    Clinical science (London, England : 1979), 2020, 05-15, Volume: 134, Issue:9

    Topics: ADAM17 Protein; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Factor XII; Mice

2020
Excessive EP4 Signaling in Smooth Muscle Cells Induces Abdominal Aortic Aneurysm by Amplifying Inflammation.
    Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:6

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Calcium Chloride; Gene Expression; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Macrophages; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Mice, Transgenic; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein-Lysine 6-Oxidase; Receptors, Cytokine; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction

2020
Bmal1 Deletion in Myeloid Cells Attenuates Atherosclerotic Lesion Development and Restrains Abdominal Aortic Aneurysm Formation in Hyperlipidemic Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:6

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; ARNTL Transcription Factors; Atherosclerosis; Cells, Cultured; Crosses, Genetic; Diet, High-Fat; Gene Deletion; Gene Expression; Hyperlipidemias; Inflammation; Integrases; Macrophages, Peritoneal; Mice; Mice, Knockout; Muramidase; Myeloid Cells; Promoter Regions, Genetic; Receptors, LDL

2020
Collagen fibril abnormalities in human and mice abdominal aortic aneurysm.
    Acta biomaterialia, 2020, 07-01, Volume: 110

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Collagen; Disease Models, Animal; Extracellular Matrix; Humans; Mice; Mice, Knockout

2020
Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB.
    Circulation, 2020, 08-04, Volume: 142, Issue:5

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Aminopropionitrile; Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cholesterol; Disease Models, Animal; Down-Regulation; Drug Evaluation, Preclinical; Gain of Function Mutation; Gene Expression Regulation; Genetic Vectors; Humans; Loss of Function Mutation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Transcriptome

2020
Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm.
    Cardiovascular research, 2021, 02-22, Volume: 117, Issue:3

    Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Case-Control Studies; Cell Adhesion; Cells, Cultured; Disease Models, Animal; Dynamins; Humans; Leukocytes; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Mitochondria, Muscle; Mitochondrial Dynamics; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxygen Consumption; Phosphorylation; Quinazolinones

2021
AT2R agonist NP-6A4 mitigates aortic stiffness and proteolytic activity in mouse model of aneurysm.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:13

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice, Knockout; Osteopontin; Phenotype; Proteolysis; Receptor, Angiotensin, Type 2; Vascular Stiffness

2020
MiR-126a-5p limits the formation of abdominal aortic aneurysm in mice and decreases ADAMTS-4 expression.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:14

    Topics: ADAMTS4 Protein; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Biopsy; Cells, Cultured; Disease Models, Animal; Disease Susceptibility; Extracellular Matrix; Gene Expression Regulation; Humans; Mice; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA Interference

2020
Reduced Nhe1 (Na
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:1

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Blood Glucose; Cells, Cultured; Endothelial Cells; Fluorescent Dyes; Genotype; Humans; Hydrogen-Ion Concentration; Immunoglobulin E; Lipids; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Receptors, IgE; Rhodamines; Sodium-Hydrogen Exchanger 1; Tumor Protein, Translationally-Controlled 1

2020
LncRNA LBX2-AS1 facilitates abdominal aortic aneurysm through miR-4685-5p/LBX2 feedback loop.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 129

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Disease Progression; Feedback, Physiological; Female; Gene Expression Regulation; Homeodomain Proteins; Humans; Mice; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; Signal Transduction

2020
Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2.
    EBioMedicine, 2020, Volume: 57

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Carboxy-Lyases; China; Disease Models, Animal; Humans; Inflammation; Kelch-Like ECH-Associated Protein 1; Macrophages; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NF-E2-Related Factor 2; Succinates

2020
MiR-126-5p promotes contractile switching of aortic smooth muscle cells by targeting VEPH1 and alleviates Ang II-induced abdominal aortic aneurysm in mice.
    Laboratory investigation; a journal of technical methods and pathology, 2020, Volume: 100, Issue:12

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Differentiation; Cells, Cultured; Male; Mice; Mice, Transgenic; MicroRNAs; Muscle, Smooth, Vascular; Nerve Tissue Proteins

2020
Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation.
    PloS one, 2020, Volume: 15, Issue:7

    Topics: Adventitia; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cholesterol; Collagen Type I; Disease Models, Animal; Fibrosis; Mice; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; Osteoprotegerin; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation

2020
All-trans retinoic acid attenuates the progression of Ang II-induced abdominal aortic aneurysms in ApoE
    Journal of cardiothoracic surgery, 2020, Jul-02, Volume: 15, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Tretinoin

2020
Simvastatin Attenuates Abdominal Aortic Aneurysm Formation Favoured by Lack of Nrf2 Transcriptional Activity.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Collagen; Elastin; Humans; Inflammation; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction; Simvastatin; Transcription, Genetic; Vascular Cell Adhesion Molecule-1

2020
Ex vivo magnetic particle imaging of vascular inflammation in abdominal aortic aneurysm in a murine model.
    Scientific reports, 2020, 07-24, Volume: 10, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Feasibility Studies; Humans; Inflammation; Magnetic Iron Oxide Nanoparticles; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout, ApoE

2020
Identification of potential proteases for abdominal aortic aneurysm by weighted gene coexpression network analysis.
    Genome, 2020, Volume: 63, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Biomarkers; Gene Expression Profiling; Gene Regulatory Networks; Male; Mice; Mice, Knockout, ApoE; Peptide Hydrolases; Transcriptome

2020
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
    PLoS biology, 2020, Volume: 18, Issue:8

    Topics: Aged; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Cellular Senescence; Echocardiography; Endothelial Cells; Eukaryotic Translation Initiation Factor 5A; Female; GTP Phosphohydrolases; Humans; Kruppel-Like Transcription Factors; Male; Mice; Mice, Knockout; Mitochondria; Mitochondrial Dynamics; Peptide Initiation Factors; Primary Cell Culture; Promoter Regions, Genetic; Protein Binding; Reactive Oxygen Species; RNA-Binding Proteins

2020
Recognizing the evolving and beneficial role of regulatory T cells in aneurysm growth.
    Journal of vascular surgery, 2020, Volume: 72, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Mice; T-Lymphocytes, Regulatory

2020
LncRNA SENCR suppresses abdominal aortic aneurysm formation by inhibiting smooth muscle cells apoptosis and extracellular matrix degradation.
    Bosnian journal of basic medical sciences, 2021, Apr-30, Volume: 21, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Cells, Cultured; Disease Models, Animal; Down-Regulation; Extracellular Matrix; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; Signal Transduction; Tissue Inhibitor of Metalloproteinases

2021
Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm.
    Experimental & molecular medicine, 2020, Volume: 52, Issue:9

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Biomarkers; Biopsy; Cell Adhesion Molecules; Cytokines; Disease Models, Animal; Disease Susceptibility; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Mice; Mice, Knockout; Models, Biological; Myocytes, Smooth Muscle; Peroxiredoxins; Reactive Oxygen Species; Ultrasonography

2020
Vitamin D deficiency promotes large rupture-prone abdominal aortic aneurysms and cholecalciferol supplementation limits progression of aneurysms in a mouse model.
    Clinical science (London, England : 1979), 2020, 09-30, Volume: 134, Issue:18

    Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Blood Pressure; Caloric Restriction; Cholecalciferol; Dietary Supplements; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Humans; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Up-Regulation; Vitamin D Deficiency

2020
Early Morphofunctional Changes in AngII-Infused Mice Contribute to Regional Onset of Aortic Aneurysm and Dissection.
    Journal of vascular research, 2020, Volume: 57, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortography; Computed Tomography Angiography; Dilatation, Pathologic; Disease Models, Animal; Endothelium, Vascular; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Time Factors; Vascular Remodeling; Vasoconstriction; X-Ray Microtomography

2020
Prevention of Progression of Aortic Aneurysm by Peptide Vaccine Against Ang II (Angiotensin II) in a Rat Model.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:6

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; Hemocyanins; Immunoconjugates; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Rats, Wistar; Signal Transduction; Vaccines, Subunit

2020
Gal-1 (Galectin-1) Upregulation Contributes to Abdominal Aortic Aneurysm Progression by Enhancing Vascular Inflammation.
    Arteriosclerosis, thrombosis, and vascular biology, 2021, Volume: 41, Issue:1

    Topics: Adventitia; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Case-Control Studies; Cells, Cultured; Cytokines; Disease Models, Animal; Disease Progression; Extracellular Matrix; Fibroblasts; Galectin 1; Humans; Inflammation Mediators; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout, ApoE; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction; Up-Regulation; Vascular Remodeling

2021
Specific inhibition of SHP2 suppressed abdominal aortic aneurysm formation in mice by augmenting the immunosuppressive function of MDSCs.
    Life sciences, 2021, Jan-15, Volume: 265

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Benzenesulfonates; Disease Models, Animal; Hydrazones; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Myeloid-Derived Suppressor Cells; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Signal Transduction

2021
Factor Xa inhibitor rivaroxaban suppresses experimental abdominal aortic aneurysm progression via attenuating aortic inflammation.
    Vascular pharmacology, 2021, Volume: 136

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Calcium Chloride; Cell Adhesion Molecules; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Factor Xa Inhibitors; Humans; Inflammation Mediators; Male; Mice, Knockout, ApoE; Retrospective Studies; Rivaroxaban; Signal Transduction; Vascular Remodeling

2021
Prevention of CaCl
    Nature communications, 2020, 11-25, Volume: 11, Issue:1

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Chemokine CCL3; Disease Models, Animal; Humans; Inflammation Mediators; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Receptors, CCR1; Receptors, CCR5; Signal Transduction; Specific Pathogen-Free Organisms

2020
TREM-1 orchestrates angiotensin II-induced monocyte trafficking and promotes experimental abdominal aortic aneurysm.
    The Journal of clinical investigation, 2021, 01-19, Volume: 131, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cell Movement; Gene Deletion; Humans; Interleukin-1beta; Matrix Metalloproteinase 2; Mice; Mice, Knockout, ApoE; Monocytes; Triggering Receptor Expressed on Myeloid Cells-1; Tumor Necrosis Factor-alpha

2021
TRPV5 attenuates abdominal aortic aneurysm in mice by regulating KLF4-dependent phenotype switch of aortic vascular smooth muscle cells.
    Archives of biochemistry and biophysics, 2021, 02-15, Volume: 698

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Calcium Channels; Cell Differentiation; Dependovirus; Down-Regulation; Gene Transfer Techniques; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; MAP Kinase Signaling System; Mice; Muscle, Smooth, Vascular; TRPV Cation Channels; Up-Regulation

2021
The C57Bl/6J mouse strain is more susceptible to angiotensin II-induced aortic aneurysm formation than C57Bl/6N.
    Atherosclerosis, 2021, Volume: 318

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Phenotype

2021
Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apoe
    Journal of atherosclerosis and thrombosis, 2022, Jan-01, Volume: 29, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Chemokine CCL2; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Monocytes; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolines

2022
A Dual Role of Heme Oxygenase-1 in Angiotensin II-Induced Abdominal Aortic Aneurysm in the Normolipidemic Mice.
    Cells, 2021, 01-15, Volume: 10, Issue:1

    Topics: Aneurysm; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cardiovascular Diseases; Cell Line; Collagen; Genotype; Heme Oxygenase-1; Humans; Hyperlipidemias; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Oxidative Stress; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 2; Serpin E2; Skin; Swine; Tissue Inhibitor of Metalloproteinase-2

2021
Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway.
    Aging, 2021, 02-01, Volume: 13, Issue:4

    Topics: ADAM10 Protein; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Calcium Chloride; Cell Movement; Chromones; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Morpholines; Neuropeptides; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Hormones; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Notch1; Transcription Factor HES-1

2021
Inhibition of CXCR2 alleviates the development of abdominal aortic aneurysm in Apo E-/- mice.
    Acta cirurgica brasileira, 2021, Volume: 36, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Macrophages; Mice; Mice, Inbred C57BL; Receptors, Interleukin-8B

2021
MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm.
    Redox biology, 2021, Volume: 41

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Trans-Activators

2021
MicroRNA-23b prevents aortic aneurysm formation by inhibiting smooth muscle cell phenotypic switching via FoxO4 suppression.
    Life sciences, 2022, Jan-01, Volume: 288

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cell Cycle Proteins; Forkhead Transcription Factors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; MicroRNAs; Myocytes, Smooth Muscle; Phenotype

2022
Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2021, 05-05, Volume: 41, Issue:5

    Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Calpain; Cells, Cultured; Cytoskeleton; Dilatation, Pathologic; Disease Models, Animal; Extracellular Matrix; Female; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Rats; Receptors, LDL; Vascular Remodeling

2021
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms.
    The Journal of experimental medicine, 2021, 06-07, Volume: 218, Issue:6

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Histone Demethylases; Inflammation; Inflammation Mediators; Jumonji Domain-Containing Histone Demethylases; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Up-Regulation

2021
Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling.
    The Journal of clinical investigation, 2021, 05-17, Volume: 131, Issue:10

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Becaplermin; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Thymosin

2021
Systemic delivery of targeted nanotherapeutic reverses angiotensin II-induced abdominal aortic aneurysms in mice.
    Scientific reports, 2021, 04-21, Volume: 11, Issue:1

    Topics: Angiotensin II; Animals; Antibodies; Aortic Aneurysm, Abdominal; Drug Delivery Systems; Elastin; Hydrolyzable Tannins; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Serum Albumin, Bovine

2021
Effects of Endogenous Angiotensin II on Abdominal Aortic Aneurysms and Atherosclerosis in Angiotensin II-Infused Mice.
    Journal of the American Heart Association, 2021, 05-04, Volume: 10, Issue:9

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Disease Models, Animal; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Vasoconstrictor Agents

2021
Computed tomography imaging of macrophage phagocytic activity in abdominal aortic aneurysm.
    Theranostics, 2021, Volume: 11, Issue:12

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Macrophages; Male; Mice; Mice, Inbred C57BL; Phagocytes; Tomography, X-Ray Computed

2021
Adventitial recruitment of Lyve-1- macrophages drives aortic aneurysm in an angiotensin-2-based murine model.
    Clinical science (London, England : 1979), 2021, 05-28, Volume: 135, Issue:10

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Inflammation Mediators; Macrophages; Membrane Transport Proteins; Mice; Signal Transduction

2021
Senolytic agents lessen the severity of abdominal aortic aneurysm in aged mice.
    Experimental gerontology, 2021, Volume: 151

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout

2021
Omentin attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice.
    Cardiovascular research, 2022, 05-06, Volume: 118, Issue:6

    Topics: Adipokines; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cytokines; Disease Models, Animal; GPI-Linked Proteins; Lectins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins c-akt

2022
CCL7 contributes to angiotensin II-induced abdominal aortic aneurysm by promoting macrophage infiltration and pro-inflammatory phenotype.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:15

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cell Differentiation; Cell Movement; Cells, Cultured; Chemokine CCL7; Human Umbilical Vein Endothelial Cells; Humans; Janus Kinase 2; Macrophages; Male; Mice; Mice, Inbred C57BL; Phenotype; Receptors, CCR1; STAT1 Transcription Factor; Vascular Remodeling

2021
Artesunate Attenuated the Progression of Abdominal Aortic Aneurysm in a Mouse Model.
    The Journal of surgical research, 2021, Volume: 267

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Artesunate; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL

2021
Cyclic nucleotide phosphodiesterase 1C contributes to abdominal aortic aneurysm.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 08-03, Volume: 118, Issue:31

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; beta-Galactosidase; Biomarkers; Cellular Senescence; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Regulation, Enzymologic; Histones; Male; Mice; Mice, Knockout, ApoE; RNA, Messenger; Sirtuin 1; Up-Regulation

2021
Angiotensin II triggers release of neutrophil extracellular traps, linking thromboinflammation with essential hypertension.
    JCI insight, 2021, 09-22, Volume: 6, Issue:18

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Aortic Aneurysm, Abdominal; Autophagy; Case-Control Studies; Cells, Cultured; Coculture Techniques; Collagen; Endothelium; Essential Hypertension; Extracellular Traps; Humans; Kidney; Neutrophils; Reactive Oxygen Species; Thrombin; Thromboinflammation; Thromboplastin; Vasoconstrictor Agents

2021
Allosteric activation of PP2A inhibits experimental abdominal aortic aneurysm.
    Clinical science (London, England : 1979), 2021, 09-17, Volume: 135, Issue:17

    Topics: Allosteric Regulation; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Case-Control Studies; Dilatation, Pathologic; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Extracellular Signal-Regulated MAP Kinases; Humans; Macrophages; Male; Mice; Mice, Knockout, ApoE; NF-kappa B; Protein Phosphatase 2; RAW 264.7 Cells; Vascular Remodeling

2021
Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression.
    Journal of the American Heart Association, 2021, 09-07, Volume: 10, Issue:17

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Fibrosis; Genomics; Humans; Mice; Mice, Inbred C57BL; Pancreatic Elastase; Swine

2021
High serum thrombospondin-1 concentration is associated with slower abdominal aortic aneurysm growth and deficiency of thrombospondin-1 promotes angiotensin II induced aortic aneurysm in mice.
    Clinical science (London, England : 1979), 2017, Jun-01, Volume: 131, Issue:12

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Cells, Cultured; Collagen Type III; Disease Models, Animal; Disease Progression; Elastin; Genetic Predisposition to Disease; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Male; Matrix Metalloproteinase 9; Mice, Knockout; Odds Ratio; Phenotype; Proteolysis; Receptors, LDL; Risk Factors; Thrombospondin 1; Time Factors; Tumor Suppressor Proteins; Ultrasonography; Vascular Remodeling

2017
Inhibition of endoplasmic reticulum stress signaling pathway: A new mechanism of statins to suppress the development of abdominal aortic aneurysm.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Atorvastatin; Calcium Chloride; Cell Line; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Random Allocation

2017
Relaxin and Matrix Metalloproteinase-9 in Angiotensin II-Induced Abdominal Aortic Aneurysms.
    Circulation journal : official journal of the Japanese Circulation Society, 2017, May-25, Volume: 81, Issue:6

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Relaxin

2017
Recombinant adeno-associated virus vector carrying the thrombomodulin lectin-like domain for the treatment of abdominal aortic aneurysm.
    Atherosclerosis, 2017, Volume: 262

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Cytokines; Dependovirus; Disease Models, Animal; Elastin; Genetic Therapy; Genetic Vectors; HMGB1 Protein; Macrophages; Male; Matrix Metalloproteinases; Mice, Knockout, ApoE; Oxidative Stress; Protein Domains; Receptor for Advanced Glycation End Products; Thrombomodulin; Vascular Remodeling

2017
Gingival fibroblasts protect against experimental abdominal aortic aneurysm development and rupture through tissue inhibitor of metalloproteinase-1 production.
    Cardiovascular research, 2017, Sep-01, Volume: 113, Issue:11

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Gingiva; Mice, Inbred C57BL; Mice, Knockout; Protective Agents; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta

2017
UCP-2 is involved in angiotensin-II-induced abdominal aortic aneurysm in apolipoprotein E-knockout mice.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Actins; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Endothelial Cells; Gene Expression Regulation; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; RNA, Messenger; Signal Transduction; Superoxide Dismutase; Uncoupling Protein 2

2017
TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:11

    Topics: Adventitia; Angiotensin II; Animals; Antibodies; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Phenotype; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Severity of Illness Index; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Transforming Growth Factor beta3; Tunica Media; Vascular Remodeling

2017
Ultraviolet B Exposure Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice by Expanding CD4
    Journal of the American Heart Association, 2017, Aug-31, Volume: 6, Issue:9

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Cell Proliferation; Cholesterol, Dietary; Disease Models, Animal; Forkhead Transcription Factors; Lymph Nodes; Lymphocyte Activation; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phenotype; T-Lymphocytes, Regulatory; Time Factors; Ultraviolet Therapy

2017
Genetic Ablation of MicroRNA-33 Attenuates Inflammation and Abdominal Aortic Aneurysm Formation via Several Anti-Inflammatory Pathways.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:11

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Apolipoproteins E; Bone Marrow Transplantation; Calcium Chloride; Cell Line; Chemokine CCL2; Cholesterol, HDL; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Humans; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phenotype; Signal Transduction; Time Factors; Transfection; Vascular Remodeling

2017
Angiotensin II infusion into ApoE-/- mice: a model for aortic dissection rather than abdominal aortic aneurysm?
    Cardiovascular research, 2017, Aug-01, Volume: 113, Issue:10

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortography; Computed Tomography Angiography; Disease Models, Animal; Disease Progression; Hematoma; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Time Factors; Ultrasonography, Doppler, Pulsed; Vascular Remodeling; X-Ray Microtomography

2017
Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 70, Issue:5

    Topics: ADAM17 Protein; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; ErbB Receptors; Hypertension; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Protein-Lysine 6-Oxidase; Receptor Activity-Modifying Proteins; Signal Transduction

2017
Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine.
    American journal of physiology. Heart and circulatory physiology, 2017, Dec-01, Volume: 313, Issue:6

    Topics: Angiotensin II; Animals; Antioxidants; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Disease Models, Animal; Gene Deletion; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Neutrophils; Oxidative Stress; Pancreatic Elastase; Peroxidase; Reactive Oxygen Species; Serum Amyloid A Protein; Taurine

2017
New Mouse Model of Abdominal Aortic Aneurysm: Put Out to Expand.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:11

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice

2017
Sex Chromosome Complement Defines Diffuse Versus Focal Angiotensin II-Induced Aortic Pathology.
    Arteriosclerosis, thrombosis, and vascular biology, 2018, Volume: 38, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Female; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Phenotype; Receptors, LDL; Sex Characteristics; Sex Factors; Sex-Determining Region Y Protein; Testosterone; Vascular Remodeling; Vascular Stiffness; X Chromosome; Y Chromosome

2018
Elevated Wall Tension Initiates Interleukin-6 Expression and Abdominal Aortic Dilation.
    Annals of vascular surgery, 2018, Volume: 46

    Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Arterial Pressure; CD11b Antigen; Cells, Cultured; Chemokine CCL2; Dilatation, Pathologic; Disease Models, Animal; Female; Interleukin-6; Macrophages; Male; Mechanotransduction, Cellular; Mice; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; STAT3 Transcription Factor; Stress, Mechanical

2018
Recombinant Decorin Fusion Protein Attenuates Murine Abdominal Aortic Aneurysm Formation and Rupture.
    Scientific reports, 2017, Nov-20, Volume: 7, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Decorin; Disease Models, Animal; Humans; Mice; Mice, Knockout; Recombinant Proteins

2017
Angiotensin II Infusion Does Not Cause Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Rats.
    Journal of vascular research, 2018, Volume: 55, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol; Disease Models, Animal; Gene Knockout Techniques; Genetic Predisposition to Disease; Phenotype; Rats, Sprague-Dawley; Rats, Transgenic; Time Factors; Ultrasonography, Doppler

2018
Cortistatin attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the ERK1/2 signaling pathways.
    Biochemical and biophysical research communications, 2018, 01-08, Volume: 495, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Cell Line; Disease Models, Animal; Elastin; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Myocytes, Smooth Muscle; Neuropeptides; Proteolysis; Reactive Oxygen Species

2018
Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression.
    Scientific reports, 2017, 12-11, Volume: 7, Issue:1

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cadherins; Cell Proliferation; Disease Models, Animal; Humans; Male; Matrix Metalloproteinase 7; Mice; Mice, Inbred C57BL; Mice, Knockout; Severity of Illness Index; Signal Transduction

2017
Cardiac and respiratory-gated volumetric murine ultrasound.
    The international journal of cardiovascular imaging, 2018, Volume: 34, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Biomechanical Phenomena; Cardiac-Gated Imaging Techniques; Disease Models, Animal; Echocardiography, Four-Dimensional; Heart Ventricles; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Myocardial Infarction; Predictive Value of Tests; Reproducibility of Results; Respiratory-Gated Imaging Techniques; Vascular Stiffness; Ventricular Function, Left

2018
Peptidyl-prolyl isomerase Pin1 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in ApoE
    Journal of molecular and cellular cardiology, 2018, Volume: 114

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Movement; Cell Proliferation; Cytokines; Humans; Inflammation Mediators; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mice, Knockout; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; NIMA-Interacting Peptidylprolyl Isomerase; Phenotype; Promoter Regions, Genetic; STAT Transcription Factors; Up-Regulation

2018
Loss of vascular smooth muscle cell autophagy exacerbates angiotensin II-associated aortic remodeling.
    Journal of vascular surgery, 2018, Volume: 68, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Autophagy; Hemodynamics; Mice; Mice, Knockout; Muscle, Smooth, Vascular

2018
Fucoidan attenuates angiotensin II-induced abdominal aortic aneurysms through the inhibition of c-Jun N-terminal kinase and nuclear factor κB activation.
    Journal of vascular surgery, 2018, Volume: 68, Issue:6S

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cells, Cultured; Collagenases; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phosphorylation; Polysaccharides; Protein Kinase Inhibitors; Signal Transduction; Transcription Factor RelA; Vascular Remodeling

2018
Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury.
    Nature communications, 2018, 01-02, Volume: 9, Issue:1

    Topics: Allosteric Regulation; Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; HEK293 Cells; Homocysteine; Humans; Male; Mice, Inbred C57BL; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Protein Conformation; Receptor, Angiotensin, Type 1; Vascular System Injuries

2018
Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).
    Diabetes, 2018, Volume: 67, Issue:4

    Topics: Adult; Aged; Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Aortic Rupture; Autoantigens; Collagen; Diabetes Mellitus, Experimental; Female; Gene Expression Regulation; Humans; Macrophages; Male; Matrix Metalloproteinase 12; Mice; Mice, Knockout; Mice, Knockout, ApoE; Middle Aged; Severity of Illness Index; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Vasoconstrictor Agents

2018
CD1d deficiency inhibits the development of abdominal aortic aneurysms in LDL receptor deficient mice.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: Angiotensin II; Animals; Antigens, CD1d; Aortic Aneurysm, Abdominal; Apoptosis; Flow Cytometry; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Natural Killer T-Cells; NIH 3T3 Cells; Real-Time Polymerase Chain Reaction; Receptors, LDL

2018
Mouse macrophage specific knockout of SIRT1 influences macrophage polarization and promotes angiotensin II-induced abdominal aortic aneurysm formation.
    Journal of genetics and genomics = Yi chuan xue bao, 2018, 01-20, Volume: 45, Issue:1

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Arginase; Cell Polarity; Disease Models, Animal; Humans; Lectins, C-Type; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Knockout; Nitric Oxide Synthase Type II; Receptors, Cell Surface; Signal Transduction; Sirtuin 1

2018
Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis.
    Scientific reports, 2018, 02-02, Volume: 8, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; Disease Models, Animal; Imaging, Three-Dimensional; Male; Mice; Mice, Inbred C57BL; Microscopy, Phase-Contrast; Synchrotrons

2018
Defective p27 phosphorylation at serine 10 affects vascular reactivity and increases abdominal aortic aneurysm development via Cox-2 activation.
    Journal of molecular and cellular cardiology, 2018, Volume: 116

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 2; Endothelial Cells; Enzyme Activation; Mice, Inbred C57BL; Phosphorylation; Phosphoserine; Thromboxanes; Vasodilation; Ventricular Remodeling

2018
Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 02-20, Volume: 115, Issue:8

    Topics: Acetates; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Chemokine CCL3; Cyclopropanes; Disease Models, Animal; Leukotriene Antagonists; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Quinolines; Receptors, Leukotriene; Sulfides

2018
Cilostazol Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysms but Not Atherosclerosis in Apolipoprotein E-Deficient Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2018, Volume: 38, Issue:4

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atherosclerosis; Cell Adhesion Molecules; Cells, Cultured; Cilostazol; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Endothelial Cells; Male; Mice, Knockout, ApoE; Phosphodiesterase 3 Inhibitors; Signal Transduction

2018
Deletion of BMAL1 in Smooth Muscle Cells Protects Mice From Abdominal Aortic Aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2018, Volume: 38, Issue:5

    Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; ARNTL Transcription Factors; Binding Sites; Desoxycorticosterone Acetate; Dilatation, Pathologic; Disease Models, Animal; Elastin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Sodium Chloride, Dietary; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic

2018
Inhibition of miR-155 attenuates abdominal aortic aneurysm in mice by regulating macrophage-mediated inflammation.
    Bioscience reports, 2018, 06-29, Volume: 38, Issue:3

    Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Movement; Cell Proliferation; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; MicroRNAs; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type II

2018
Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Cell Survival; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Indoleamine-Pyrrole 2,3,-Dioxygenase; Macrophages; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, LDL; T-Lymphocytes

2018
Ursolic acid prevents angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-knockout mice.
    Atherosclerosis, 2018, Volume: 271

    Topics: ADAM17 Protein; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Line; Cell Proliferation; Disease Models, Animal; Elastin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Ursolic Acid; Vascular Remodeling; Wound Healing

2018
CD40L Deficiency Protects Against Aneurysm Formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2018, Volume: 38, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; CD40 Ligand; Chemokines; Cytokines; Dilatation, Pathologic; Disease Models, Animal; Humans; Male; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout, ApoE; Tissue Inhibitor of Metalloproteinase-3

2018
Plasma cholesterol lowering in an AngII‑infused atherosclerotic mouse model with moderate hypercholesterolemia.
    International journal of molecular medicine, 2018, Volume: 42, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoprotein B-100; Atherosclerosis; Cholesterol; Disease Models, Animal; Gene Expression Regulation; Hypercholesterolemia; Integrases; Male; Receptors, LDL

2018
H19 Induces Abdominal Aortic Aneurysm Development and Progression.
    Circulation, 2018, 10-09, Volume: 138, Issue:15

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Case-Control Studies; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pancreatic Elastase; Receptors, LDL; RNA, Long Noncoding; Swine; Swine, Miniature; Tumor Suppressor Protein p53; Up-Regulation

2018
RANKL-mediated osteoclastogenic differentiation of macrophages in the abdominal aorta of angiotensin II-infused apolipoprotein E knockout mice.
    Journal of vascular surgery, 2018, Volume: 68, Issue:6S

    Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Cell Transdifferentiation; Disease Models, Animal; Janus Kinase 2; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteoclasts; Osteogenesis; RANK Ligand; RAW 264.7 Cells; Signal Transduction; STAT5 Transcription Factor

2018
Development and growth trends in angiotensin II-induced murine dissecting abdominal aortic aneurysms.
    Physiological reports, 2018, Volume: 6, Issue:8

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Apolipoproteins E; Disease Models, Animal; Disease Progression; Male; Mice; Ultrasonography

2018
Ginkgo biloba extracts prevent aortic rupture in angiotensin II-infused hypercholesterolemic mice.
    Acta pharmacologica Sinica, 2019, Volume: 40, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Ginkgo biloba; Male; Mice, Inbred C57BL; Mice, Knockout; Plant Extracts

2019
PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 104

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; beta-Galactosidase; Biomarkers; Cell Line; Chemokine CCL2; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Elastin; Humans; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Particulate Matter; Reactive Oxygen Species

2018
Inhibition of endoplasmic reticulum stress by intermedin1-53 attenuates angiotensin II-induced abdominal aortic aneurysm in ApoE KO Mice.
    Endocrine, 2018, Volume: 62, Issue:1

    Topics: Adenylate Kinase; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Endoplasmic Reticulum Stress; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Hormones; Phosphorylation

2018
Embelin inhibits abdominal aortic aneurysm through decreasing IL‑6‑induced STAT3 and NF‑κB inactivation.
    Molecular medicine reports, 2018, Volume: 18, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Benzoquinones; Disease Models, Animal; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Humans; Interleukin-6; Mice; NF-kappa B; Phosphorylation; STAT3 Transcription Factor

2018
Effect of irradiation and bone marrow transplantation on angiotensin II-induced aortic inflammation in ApoE knockout mice.
    Atherosclerosis, 2018, Volume: 276

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Rupture; Aortitis; Atherosclerosis; Bone Marrow Transplantation; Disease Models, Animal; Macrophages; Male; Mice, Knockout, ApoE; Monocytes; Plaque, Atherosclerotic; Whole-Body Irradiation

2018
Recombinant leptin attenuates abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.
    Biochemical and biophysical research communications, 2018, 09-10, Volume: 503, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Inflammation; Injections, Intraperitoneal; Leptin; Mice; Mice, Inbred C57BL; Mice, Knockout; Recombinant Proteins; T-Lymphocytes; Th1 Cells

2018
PPARγ agonist rosiglitazone alters the temporal and spatial distribution of inflammation during abdominal aortic aneurysm formation.
    Molecular medicine reports, 2018, Volume: 18, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Disease Models, Animal; Inflammation; Male; Mice; Mice, Knockout; Models, Biological; PPAR gamma; Rosiglitazone; Th2 Cells; Thiazolidinediones; Vasodilator Agents

2018
Rapamycin Treatment Attenuates Angiotensin II -induced Abdominal Aortic Aneurysm Formation via VSMC Phenotypic Modulation and Down-regulation of ERK1/2 Activity.
    Current medical science, 2018, Volume: 38, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Down-Regulation; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Sirolimus

2018
A diet enriched with tree nuts reduces severity of atherosclerosis but not abdominal aneurysm in angiotensin II-infused apolipoprotein E deficient mice.
    Atherosclerosis, 2018, Volume: 277

    Topics: Angiotensin II; Animal Feed; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Diseases; Atherosclerosis; Brachiocephalic Trunk; Dilatation, Pathologic; Disease Models, Animal; Fatty Acids, Omega-3; Male; Mice, Knockout, ApoE; Nutritive Value; Nuts; Plaque, Atherosclerotic; Polyphenols; Severity of Illness Index; Time Factors

2018
Inhibitory effects of cycloastragenol on abdominal aortic aneurysm and its related mechanisms.
    British journal of pharmacology, 2019, Volume: 176, Issue:2

    Topics: Administration, Oral; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Conformation; Oxidative Stress; Pancreatic Elastase; Rats; Rats, Sprague-Dawley; Sapogenins; Signal Transduction

2019
PARP-1 (Poly[ADP-Ribose] Polymerase 1) Inhibition Protects From Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysm in Mice.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Blood Pressure; Collagen; Cytokines; DNA Damage; Endothelial Cells; Intercellular Adhesion Molecule-1; Mice; Mice, Knockout; Myocytes, Smooth Muscle; NF-kappa B; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; RNA, Small Interfering; Signal Transduction

2018
PARP-1 (Poly[ADP-Ribose] Polymerase-1).
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:5

    Topics: Adenosine Diphosphate Ribose; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Mice

2018
Long-Term Effects of the Abdominal Aortic Aneurysm Model in Rabbits Prepared by Pancreatic Elastase Combined With Angiotensin II.
    Vascular and endovascular surgery, 2019, Volume: 53, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Hemodynamics; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pancreatic Elastase; Rabbits; Time Factors; Ultrasonography, Doppler, Color; Vascular Remodeling

2019
von Willebrand factor deficiency does not influence angiotensin II-induced abdominal aortic aneurysm formation in mice.
    Scientific reports, 2018, 11-09, Volume: 8, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Dilatation, Pathologic; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Vasoconstrictor Agents; von Willebrand Factor

2018
Licochalcone A attenuates abdominal aortic aneurysm induced by angiotensin II via regulating the miR-181b/SIRT1/HO-1 signaling.
    Journal of cellular physiology, 2019, Volume: 234, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Chalcones; Cytokines; Disease Models, Animal; Heme Oxygenase-1; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; MicroRNAs; Signal Transduction; Sirtuin 1

2019
Invited commentary.
    Journal of vascular surgery, 2018, Volume: 68, Issue:6S

    Topics: Angiotensin II; Aortic Aneurysm, Abdominal; Humans; JNK Mitogen-Activated Protein Kinases; NF-kappa B; Polysaccharides

2018
Gambogic acid prevents angiotensin II‑induced abdominal aortic aneurysm through inflammatory and oxidative stress dependent targeting the PI3K/Akt/mTOR and NF‑κB signaling pathways.
    Molecular medicine reports, 2019, Volume: 19, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Garcinia; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Xanthones

2019
Chemokine (C-X-C motif) receptor 2 blockade by SB265610 inhibited angiotensin II-induced abdominal aortic aneurysm in Apo E
    Heart and vessels, 2019, Volume: 34, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Macrophages; Male; Mice; Mice, Knockout, ApoE; Phenylurea Compounds; Receptors, Interleukin-8B; Signal Transduction; Triazoles

2019
ZFP148 (Zinc-Finger Protein 148) Binds Cooperatively With NF-1 (Neurofibromin 1) to Inhibit Smooth Muscle Marker Gene Expression During Abdominal Aortic Aneurysm Formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:1

    Topics: Acetylation; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Female; Histones; Humans; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Neurofibromin 1; Transcription Factors

2019
Circular RNA microarray expression profile in 3,4-benzopyrene/angiotensin II-induced abdominal aortic aneurysm in mice.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:6

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Benzo(a)pyrene; Disease Models, Animal; Gene Ontology; Gene Regulatory Networks; Male; Mice, Inbred C57BL; MicroRNAs; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Reproducibility of Results; RNA, Circular; Transcriptome

2019
Interleukin-6 Receptor Signaling and Abdominal Aortic Aneurysm Growth Rates.
    Circulation. Genomic and precision medicine, 2019, Volume: 12, Issue:2

    Topics: Alleles; Angiotensin II; Animals; Antibodies; Aortic Aneurysm, Abdominal; Biomarkers; Disease Models, Animal; Humans; Interleukin-6; Linear Models; Mice; Polymorphism, Single Nucleotide; Receptors, Interleukin-6; Signal Transduction; Survival Rate; Transforming Growth Factor beta

2019
Caloric Restriction Exacerbates Angiotensin II-Induced Abdominal Aortic Aneurysm in the Absence of p53.
    Hypertension (Dallas, Tex. : 1979), 2019, Volume: 73, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Caloric Restriction; Disease Models, Animal; Energy Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Signal Transduction; Tumor Suppressor Protein p53

2019
Knockdown of lncRNA
    Molecules and cells, 2019, Mar-31, Volume: 42, Issue:3

    Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Disease Models, Animal; Extracellular Matrix; Gene Knockdown Techniques; Humans; Inflammation; Mice; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; RNA, Small Interfering

2019
Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction.
    Scientific reports, 2019, 03-11, Volume: 9, Issue:1

    Topics: Aging; Angiotensin II; Animals; Antigens, Differentiation; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Calcium-Binding Proteins; Cognitive Dysfunction; Disease Models, Animal; Genes, MHC Class II; Hippocampus; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia

2019
c‑Jun/Ap‑1 is upregulated in an Ang II‑induced abdominal aortic aneurysm formation model and mediates Chop expression in mouse aortic smooth muscle cells.
    Molecular medicine reports, 2019, Volume: 19, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Gene Silencing; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Transcription Factor AP-1; Transcription Factor CHOP

2019
Concurrent Molecular Magnetic Resonance Imaging of Inflammatory Activity and Extracellular Matrix Degradation for the Prediction of Aneurysm Rupture.
    Circulation. Cardiovascular imaging, 2019, Volume: 12, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Contrast Media; Disease Models, Animal; Disease Progression; Elastin; Extracellular Matrix; Feasibility Studies; Ferrosoferric Oxide; Gadolinium DTPA; Inflammation Mediators; Magnetic Resonance Imaging; Male; Mice, Knockout, ApoE; Molecular Imaging; Predictive Value of Tests; Reproducibility of Results; Time Factors

2019
Smooth muscle-specific LKB1 deletion exaggerates angiotensin II-induced abdominal aortic aneurysm in mice.
    Journal of molecular and cellular cardiology, 2019, Volume: 130

    Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Gene Deletion; Humans; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Sp1 Transcription Factor

2019
Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction.
    Redox biology, 2019, Volume: 24

    Topics: Anemia, Megaloblastic; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Genetic Loci; Hypertension; Macrophages; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Mitochondria; Phenotype; Tetrahydrofolate Dehydrogenase; Ultrasonography

2019
LncRNA H19 promotes vascular inflammation and abdominal aortic aneurysm formation by functioning as a competing endogenous RNA.
    Journal of molecular and cellular cardiology, 2019, Volume: 131

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Long Noncoding; Signal Transduction; Transcription, Genetic; Up-Regulation

2019
Testosterone inhibits aneurysm formation and vascular inflammation in male mice.
    The Journal of endocrinology, 2019, 06-01, Volume: 241, Issue:3

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Flutamide; Inflammation; Interleukin-1beta; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Androgen; Testosterone

2019
ASB17061, a novel chymase inhibitor, prevented the development of angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice.
    European journal of pharmacology, 2019, Aug-05, Volume: 856

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Benzoic Acid; Chymases; Colitis; Enzyme Precursors; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Serine Proteinase Inhibitors

2019
Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 06-25, Volume: 116, Issue:26

    Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apelin; Apoptosis; Cardiovascular Agents; Diet, High-Fat; Disease Models, Animal; Female; Gene Knockdown Techniques; Humans; Male; Mice, Transgenic; Middle Aged; Myocytes, Smooth Muscle; Neprilysin; Oxidative Stress; Peptidyl-Dipeptidase A; Phenylephrine; Primary Cell Culture; Proteolysis; Receptors, LDL; RNA, Small Interfering; Vascular Remodeling

2019
Tropoelastin: an in vivo imaging marker of dysfunctional matrix turnover during abdominal aortic dilation.
    Cardiovascular research, 2020, 04-01, Volume: 116, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Biomarkers; Contrast Media; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Extracellular Matrix; Humans; Magnetic Resonance Imaging; Mice, Knockout, ApoE; Predictive Value of Tests; Proof of Concept Study; Time Factors; Tropoelastin; Up-Regulation; Vascular Remodeling

2020
SGLT-2 (Sodium-Glucose Cotransporter 2) Inhibition Reduces Ang II (Angiotensin II)-Induced Dissecting Abdominal Aortic Aneurysm in ApoE (Apolipoprotein E) Knockout Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:8

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Apolipoproteins E; Benzhydryl Compounds; Cells, Cultured; Chemokines; Glucosides; Humans; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Sodium-Glucose Transporter 2 Inhibitors

2019
Regulatory T cells protected against abdominal aortic aneurysm by suppression of the COX-2 expression.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:10

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Survival; Cyclooxygenase 2; Dinoprostone; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Phenotype; RAW 264.7 Cells; T-Lymphocytes, Regulatory

2019
CYP2J2 overexpression increases EETs and protects against angiotensin II-induced abdominal aortic aneurysm in mice.
    Journal of lipid research, 2013, Volume: 54, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Arachidonic Acids; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Humans; Macrophages; Mice; Muscle, Smooth, Vascular; PPAR gamma

2013
β-Arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice.
    Circulation research, 2013, Apr-26, Volume: 112, Issue:9

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arrestins; Benzamides; beta-Arrestin 2; beta-Arrestins; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinases; Chemokine CCL2; Chemokine CCL3; Cyclooxygenase 2; Disease Models, Animal; Elastic Tissue; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Signal Transduction; Time Factors

2013
Azelnidipine suppresses the progression of aortic aneurysm in wild mice model through anti-inflammatory effects.
    The Journal of thoracic and cardiovascular surgery, 2013, Volume: 146, Issue:6

    Topics: Aminopropionitrile; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Disease Models, Animal; Disease Progression; Inflammation Mediators; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Sirtuin 1; Time Factors; Tumor Necrosis Factor-alpha

2013
PD123319 augments angiotensin II-induced abdominal aortic aneurysms through an AT2 receptor-independent mechanism.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Angiotensin II; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Atherosclerosis; Genotype; Imidazoles; Male; Mice; Mice, Inbred C57BL; Pyridines; Receptor, Angiotensin, Type 2

2013
Exploration of the mechanisms by which 3,4-benzopyrene promotes angiotensin II-induced abdominal aortic aneurysm formation in mice.
    Journal of vascular surgery, 2014, Volume: 59, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Benzo(a)pyrene; Disease Models, Animal; Drug Administration Schedule; Injections, Intraperitoneal; Macrophages; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; NF-kappa B; Smoking; Time Factors

2014
β-Carotene Attenuates Angiotensin II-Induced Aortic Aneurysm by Alleviating Macrophage Recruitment in Apoe(-/-) Mice.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: alpha-Tocopherol; Angiotensin II; Animals; Antioxidants; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; beta Carotene; Cholesterol, LDL; Dietary Supplements; Disease Models, Animal; Lymphocytes; Macrophages; Male; Mice, Knockout; Organ Size; Plaque, Atherosclerotic

2013
Development of abdominal aortic aneurysm is decreased in mice with plasma phospholipid transfer protein deficiency.
    The American journal of pathology, 2013, Volume: 183, Issue:3

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; CD4-Positive T-Lymphocytes; Cytokines; Elastin; Inflammation; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phospholipid Transfer Proteins

2013
Natural regulatory T cells limit angiotensin II-induced aneurysm formation and rupture in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:10

    Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; B7-1 Antigen; B7-2 Antigen; CD28 Antigens; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Inflammation Mediators; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Leukocyte Reduction Procedures; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; T-Lymphocytes, Regulatory; Time Factors

2013
Combination therapy with atorvastatin and amlodipine suppresses angiotensin II-induced aortic aneurysm formation.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Amlodipine; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Atorvastatin; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Drug Therapy, Combination; Enzyme Activation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Pyrroles; rho-Associated Kinases

2013
Calpain-2 compensation promotes angiotensin II-induced ascending and abdominal aortic aneurysms in calpain-1 deficient mice.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Angiotensin II; Animals; Aorta; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calpain; Diet, High-Fat; Enzyme Inhibitors; Filamins; Gene Expression Regulation; Male; Mice; Mice, Knockout; Receptors, LDL; Signal Transduction; Sulfonamides

2013
Zoledronate attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of Rho/ROCK-dependent JNK and NF-κB pathway.
    Cardiovascular research, 2013, Dec-01, Volume: 100, Issue:3

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Adhesion; Cell Line; Coculture Techniques; Dilatation, Pathologic; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Elastin; Endothelial Cells; Enzyme Activation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; NF-kappa B; Phosphorylation; Receptors, LDL; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vascular Cell Adhesion Molecule-1; Zoledronic Acid

2013
Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase.
    Clinical science (London, England : 1979), 2014, Volume: 126, Issue:11

    Topics: ADAM Proteins; ADAM17 Protein; Adenoviridae; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Caveolin 1; Cells, Cultured; Gene Expression Regulation; Gene Silencing; Heparin-binding EGF-like Growth Factor; Immunohistochemistry; Inflammation; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Smooth Muscle; Oxidative Stress; Promoter Regions, Genetic; Protein-Lysine 6-Oxidase; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA Interference; Signal Transduction

2014
Notch γ-secretase inhibitor dibenzazepine attenuates angiotensin II-induced abdominal aortic aneurysm in ApoE knockout mice by multiple mechanisms.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Amyloid Precursor Protein Secretases; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Dibenzazepines; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Notch1; Signal Transduction

2013
Castration of male mice prevents the progression of established angiotensin II-induced abdominal aortic aneurysms.
    Journal of vascular surgery, 2015, Volume: 61, Issue:3

    Topics: Actins; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Cells, Cultured; Collagen; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Male; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Risk Factors; Sex Factors; Testosterone; Time Factors; Ultrasonography; Vascular Remodeling

2015
Angiotensin-induced abdominal aortic aneurysms in hypercholesterolemic mice: role of serum cholesterol and temporal effects of exposure.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cholesterol; Elastin; Hypercholesterolemia; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Time Factors; Ultrasonography

2014
Aliskiren limits abdominal aortic aneurysm, ventricular hypertrophy and atherosclerosis in an apolipoprotein-E-deficient mouse model.
    Clinical science (London, England : 1979), 2014, Volume: 127, Issue:2

    Topics: Amides; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Fumarates; Hypertension; Hypertrophy; Mice; Mice, Inbred C57BL; Mice, Knockout

2014
Recoupling of eNOS with folic acid prevents abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E null mice.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Administration, Oral; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biopterins; Folic Acid; Male; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Radiography; Superoxides; Tetrahydrofolate Dehydrogenase; Ultrasonography; Vascular Remodeling

2014
PPARδ reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice by regulating extracellular matrix homeostasis and inflammatory responses.
    International journal of cardiology, 2014, Jun-01, Volume: 174, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Extracellular Matrix; Homeostasis; Inflammation; Infusion Pumps; Male; Mice; PPAR delta

2014
Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms.
    Journal of the American Heart Association, 2014, May-08, Volume: 3, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cytoskeletal Proteins; Disease Models, Animal; DNA-Binding Proteins; LIM Domain Proteins; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Proteins; Mice, Knockout; Phosphoproteins; Reactive Oxygen Species; Signal Transduction

2014
Prevention of abdominal aortic aneurysm by anti-microRNA-712 or anti-microRNA-205 in angiotensin II-infused mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:7

    Topics: Adult; Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Case-Control Studies; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Gene Expression Profiling; GPI-Linked Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Middle Aged; Oligonucleotide Array Sequence Analysis; Oligonucleotides, Antisense; Time Factors; Tissue Inhibitor of Metalloproteinase-3; Up-Regulation

2014
Adiponectin attenuates abdominal aortic aneurysm formation in hyperlipidemic mice.
    Atherosclerosis, 2014, Volume: 235, Issue:2

    Topics: Adiponectin; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Enzyme Activation; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Knockout

2014
New ways to dismantle a ticking time bomb: microRNA 712/205 and abdominal aortic aneurysm development.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:7

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Endothelial Cells; Female; Humans; Male; MicroRNAs; Oligonucleotides, Antisense

2014
Regulatory T cells prevent angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E knockout mice.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:4

    Topics: Adoptive Transfer; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Blotting, Western; CD4-Positive T-Lymphocytes; Cytokines; Gene Expression; Humans; Inflammation Mediators; Macrophages; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myocytes, Smooth Muscle; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes, Regulatory

2014
Cathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice.
    Journal of vascular surgery, 2015, Volume: 62, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cathepsin G; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Macrophages; Mice; Myocytes, Smooth Muscle; Peptidyl-Dipeptidase A

2015
NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:11

    Topics: Angiotensin II; Animals; Antibodies; Aortic Aneurysm, Abdominal; Disease Models, Animal; Interleukin-1beta; Macrophages; Matrix Metalloproteinase 12; Matrix Metalloproteinase 9; Membrane Glycoproteins; Mice; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Reactive Oxygen Species

2014
Inhibiting the Th17/IL-17A-related inflammatory responses with digoxin confers protection against experimental abdominal aortic aneurysm.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cardiotonic Agents; Digoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nuclear Receptor Subfamily 1, Group F, Member 3; Pancreatic Elastase; Survival Rate; Swine; Th17 Cells

2014
Circulating tetrahydrobiopterin as a novel biomarker for abdominal aortic aneurysm.
    American journal of physiology. Heart and circulatory physiology, 2014, Dec-01, Volume: 307, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Biopterins; Folic Acid; Hematinics; Male; Mice; Mice, Knockout; Phenylalanine; Vasoconstrictor Agents

2014
Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:12

    Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aortic Aneurysm, Abdominal; Diminazene; Disease Models, Animal; Enzyme Activation; Female; Humans; Hypercholesterolemia; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Peptidyl-Dipeptidase A; Receptors, LDL; Renin-Angiotensin System; RNA, Messenger

2014
Osteoprotegerin deficiency limits angiotensin II-induced aortic dilatation and rupture in the apolipoprotein E-knockout mouse.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:12

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Blood Pressure; Cathepsins; Dilatation, Pathologic; Disease Models, Animal; Humans; Inflammation Mediators; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Osteoprotegerin; Pancreatic Elastase; Proteolysis

2014
High-fat diet- and angiotensin II-induced aneurysm concurrently elicits splenic hypertrophy.
    European journal of clinical investigation, 2014, Volume: 44, Issue:12

    Topics: alpha-Tocopherol; Angiotensin II; Animals; Antioxidants; Aortic Aneurysm, Abdominal; Apolipoproteins E; beta Carotene; Diet, High-Fat; Dietary Supplements; Male; Mice, Knockout; Splenomegaly; T-Lymphocytes; Vasoconstrictor Agents

2014
5-Lipoxygenase pathway in experimental abdominal aortic aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:12

    Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Arachidonate 5-Lipoxygenase; Bone Marrow Transplantation; Disease Models, Animal; Disease Progression; Humans; Hypercholesterolemia; Lipoxygenase Inhibitors; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Neutrophil Infiltration; Pancreatic Elastase; Receptors, LDL; Signal Transduction; Transplantation Chimera

2014
Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model.
    Journal of the American Heart Association, 2014, Oct-27, Volume: 3, Issue:6

    Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Differentiation; Cells, Cultured; Collagen; Dipeptides; Disease Models, Animal; Disease Progression; Elastin; Gene Expression Regulation; Humans; Macrophages; Male; Matrix Metalloproteinases; Mice, Knockout; Middle Aged; Receptor, Notch1; Signal Transduction; Time Factors; Transforming Growth Factor beta2

2014
Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:1

    Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Cells, Cultured; Disease Models, Animal; Female; Fibrosis; Humans; Inflammasomes; Inflammation Mediators; Interleukin-1beta; Macrophage Activation; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Time Factors

2015
Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:1

    Topics: Aneurysm; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Arterial Pressure; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Elastin; Gene Deletion; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Male; Matrix Metalloproteinase 2; Mesenteric Artery, Superior; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Norepinephrine; Receptors, LDL; RNA, Messenger; Tumor Suppressor Proteins; Urokinase-Type Plasminogen Activator

2015
Arrest of progression of pre-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by low level laser phototherapy.
    Lasers in surgery and medicine, 2014, Volume: 46, Issue:10

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Lasers, Semiconductor; Low-Level Light Therapy; Mice; Mice, Inbred C57BL

2014
A peptide antagonist of thrombospondin-1 promotes abdominal aortic aneurysm progression in the angiotensin II-infused apolipoprotein-E-deficient mouse.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:2

    Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cytokines; Disease Models, Animal; Disease Progression; Elastin; Inflammation Mediators; Injections, Intraperitoneal; Male; Mice, Knockout; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Smad2 Protein; Smad3 Protein; Thrombospondin 1; Time Factors; Transforming Growth Factor beta1

2015
Angiotensin II mobilizes spleen monocytes to promote the development of abdominal aortic aneurysm in Apoe-/- mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:2

    Topics: Angiotensin II; Animals; Antigens, Ly; Aortic Aneurysm, Abdominal; Apolipoproteins E; B-Lymphocytes; Bone Marrow Transplantation; Cell Movement; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Hypercholesterolemia; Male; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Spleen; Splenectomy; Time Factors

2015
Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model.
    Clinical science (London, England : 1979), 2015, Volume: 128, Issue:9

    Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Cells, Cultured; Cytoprotection; Disease Models, Animal; Endoplasmic Reticulum Stress; ErbB Receptors; Erlotinib Hydrochloride; Extracellular Matrix; Humans; Interleukin-6; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Protein Kinase Inhibitors; Quinazolines; Rats, Sprague-Dawley; Time Factors

2015
Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation.
    Cardiovascular research, 2015, Feb-01, Volume: 105, Issue:2

    Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Dissection; Contrast Media; Dilatation, Pathologic; Disease Models, Animal; Male; Mice, Inbred C57BL

2015
Imaging vessel wall biology to predict outcome in abdominal aortic aneurysm.
    Circulation. Cardiovascular imaging, 2015, Volume: 8, Issue:1

    Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Aortography; Biomarkers; Disease Models, Animal; Disease Progression; Enzyme Activation; Feasibility Studies; Male; Matrix Metalloproteinases; Mice, Inbred C57BL; Mice, Transgenic; Molecular Imaging; Multimodal Imaging; Predictive Value of Tests; Radiopharmaceuticals; Risk Assessment; Risk Factors; Time Factors; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

2015
Foxp3+ regulatory T cells play a protective role in angiotensin II-induced aortic aneurysm formation in mice.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:4

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Flow Cytometry; Forkhead Transcription Factors; Immunity, Cellular; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory

2015
Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis.
    British journal of pharmacology, 2015, Volume: 172, Issue:12

    Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bexarotene; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Rosuvastatin Calcium; Signal Transduction; Tetrahydronaphthalenes

2015
ApoB-100-related peptide vaccine protects against angiotensin II-induced aortic aneurysm formation and rupture.
    Journal of the American College of Cardiology, 2015, Feb-17, Volume: 65, Issue:6

    Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoprotein B-100; Disease Models, Animal; Immunity, Cellular; Macrophages; Male; Mice; Mice, Knockout; T-Lymphocytes; Vaccines

2015
Deficiency of Endogenous Acute-Phase Serum Amyloid A Protects apoE-/- Mice From Angiotensin II-Induced Abdominal Aortic Aneurysm Formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Disease Models, Animal; Elastin; Macrophages; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Random Allocation; Sensitivity and Specificity; Serum Amyloid A Protein

2015
ApoA-I/HDL-C levels are inversely associated with abdominal aortic aneurysm progression.
    Thrombosis and haemostasis, 2015, Volume: 113, Issue:6

    Topics: Aged; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoprotein A-I; Apolipoproteins E; Biomarkers; Cholesterol, HDL; Chromatography, Liquid; Denmark; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Humans; Linear Models; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Multivariate Analysis; Nanotechnology; Peptides; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Proteomics; Registries; Spain; Tandem Mass Spectrometry

2015
Regulatory T cells in human and angiotensin II-induced mouse abdominal aortic aneurysms.
    Cardiovascular research, 2015, Jul-01, Volume: 107, Issue:1

    Topics: Aged; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Chemokines; Forkhead Transcription Factors; Humans; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; T-Lymphocytes, Regulatory

2015
An animal-specific FSI model of the abdominal aorta in anesthetized mice.
    Annals of biomedical engineering, 2015, Volume: 43, Issue:6

    Topics: Anesthesia; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Knockout; Models, Cardiovascular

2015
Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cell Movement; Cells, Cultured; Chemotaxis; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Drug Evaluation, Preclinical; Fibroblasts; Glucagon-Like Peptide 1; Humans; Infusion Pumps, Implantable; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Monocytes; Reactive Oxygen Species; Sitagliptin Phosphate; U937 Cells

2015
Ginsenoside Rb1 attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the JNK and p38 signaling pathways.
    Vascular pharmacology, 2015, Volume: 73

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Apoptosis; Disease Models, Animal; Enzyme Activators; Extracellular Matrix; Ginsenosides; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Severity of Illness Index; Signal Transduction; Vascular Remodeling

2015
Thrombospondin-1 (TSP1) contributes to the development of vascular inflammation by regulating monocytic cell motility in mouse models of abdominal aortic aneurysm.
    Circulation research, 2015, Jul-03, Volume: 117, Issue:2

    Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bone Marrow Transplantation; Calcium Phosphates; Cell Line; Cell Movement; Disease Models, Animal; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Pancreatic Elastase; Radiation Chimera; Recombinant Proteins; Thrombospondin 1; Up-Regulation

2015
Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:8

    Topics: Angiotensin II; Animals; Anticholesteremic Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Apolipoproteins E; Azetidines; Diet, Western; Disease Models, Animal; Ezetimibe; Female; Hypercholesterolemia; Male; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL; Sex Factors

2015
Morphological and Biomechanical Differences in the Elastase and AngII apoE(-/-) Rodent Models of Abdominal Aortic Aneurysms.
    BioMed research international, 2015, Volume: 2015

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Blood Flow Velocity; Blood Pressure; Disease Models, Animal; Disease Progression; Humans; Mice; Mice, Knockout; Pancreatic Elastase; Rats

2015
Telemetric Blood Pressure Assessment in Angiotensin II-Infused ApoE-/- Mice: 28 Day Natural History and Comparison to Tail-Cuff Measurements.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Blood Pressure Determination; Gene Deletion; Male; Mice; Mice, Inbred C57BL; Telemetry

2015
Effects of long-term chloroquine administration on the natural history of aortic aneurysms in mice.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:8

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Autophagy; Chloroquine; Collagen; Disease Models, Animal; Disease Progression; Elastin; Male; Mice, Inbred C57BL; Mice, Knockout; Time Factors

2015
TRIF adaptor signaling is important in abdominal aortic aneurysm formation.
    Atherosclerosis, 2015, Volume: 241, Issue:2

    Topics: Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins; Apolipoproteins E; CD3 Complex; Elastin; Gene Expression Regulation; Humans; Inflammation; Mice; Mice, Knockout; Signal Transduction; Toll-Like Receptors

2015
Pioglitazone Identifies a New Target for Aneurysm Treatment: Role of Egr1 in an Experimental Murine Model of Aortic Aneurysm.
    Journal of vascular research, 2015, Volume: 52, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Base Sequence; Binding Sites; Calcium Chloride; Cell Line, Tumor; Disease Models, Animal; Early Growth Response Protein 1; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Macrophages; Male; Mice, Knockout; Molecular Sequence Data; Pioglitazone; PPAR gamma; Promoter Regions, Genetic; RNA Interference; Signal Transduction; Thiazolidinediones; Time Factors; Transfection; TRPP Cation Channels

2015
Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:9

    Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Disease Models, Animal; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Platelet Aggregation Inhibitors

2015
Dose-Dependent Bidirectional Effect of Angiotensin IV on Abdominal Aortic Aneurysm via Variable Angiotensin Receptor Stimulation.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 66, Issue:3

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Lipids; Mice; Mice, Knockout; Receptors, Angiotensin

2015
Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications.
    Journal of molecular and cellular cardiology, 2015, Volume: 87

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Aortic Aneurysm, Abdominal; Calcium Channels, L-Type; Humans; Hypertension; Mice; Mice, Transgenic; NADPH Oxidases; Nifedipine; Nitric Oxide Synthase Type III; Oxidative Stress; Phenylketonurias

2015
Angiotensin II-induced TLR4 mediated abdominal aortic aneurysm in apolipoprotein E knockout mice is dependent on STAT3.
    Journal of molecular and cellular cardiology, 2015, Volume: 87

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Gene Expression Regulation; Humans; Macrophages; Male; Mice; Mice, Knockout; Signal Transduction; STAT3 Transcription Factor; Toll-Like Receptor 4

2015
Membrane-Bound Thrombomodulin Regulates Macrophage Inflammation in Abdominal Aortic Aneurysm.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:11

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Calcium Chloride; Cell Membrane; Cells, Cultured; Chemotaxis; Disease Models, Animal; Elastin; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Macrophages, Peritoneal; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Retrospective Studies; RNA Interference; Signal Transduction; Thrombomodulin; Time Factors; Transfection

2015
Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice.
    Journal of visualized experiments : JoVE, 2015, Sep-28, Issue:103

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Apolipoproteins E; Disease Models, Animal; Female; Humans; Hypercholesterolemia; Infusion Pumps, Implantable; Male; Mice; Mice, Transgenic

2015
Inhibition of Proteasome Activity by Low-dose Bortezomib Attenuates Angiotensin II-induced Abdominal Aortic Aneurysm in Apo E(-/-) Mice.
    Scientific reports, 2015, Oct-28, Volume: 5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bortezomib; Disease Models, Animal; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Proteasome Endopeptidase Complex; Proteasome Inhibitors

2015
Allergic Lung Inflammation Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:1

    Topics: Angiotensin II; Animals; Anti-Allergic Agents; Antibodies, Monoclonal; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Calcium Chloride; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Immunoglobulin E; Inflammation Mediators; Lung; Macrophages; Male; Mast Cells; Mice, Inbred C57BL; Mice, Knockout; Ovalbumin; Pneumonia; Respiratory Hypersensitivity; Risk Factors; Signal Transduction; Vascular Remodeling

2016
A Dipeptidyl Peptidase-4 Inhibitor but not Incretins Suppresses Abdominal Aortic Aneurysms in Angiotensin II-Infused Apolipoprotein E-Null Mice.
    Journal of atherosclerosis and thrombosis, 2016, Volume: 23, Issue:4

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Dipeptidyl-Peptidase IV Inhibitors; Gastric Inhibitory Polypeptide; Gene Expression Regulation; Glucagon-Like Peptide 1; Incretins; Inflammation; Interleukin-1beta; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Plaque, Atherosclerotic; Tissue Inhibitor of Metalloproteinase-2

2016
Ascending Aortic Aneurysm in Angiotensin II-Infused Mice: Formation, Progression, and the Role of Focal Dissections.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:4

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; Aortic Valve Insufficiency; Aortography; Apolipoproteins E; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Elastic Tissue; Male; Mice, Inbred C57BL; Mice, Knockout; Time Factors; Ultrasonography, Doppler, Pulsed; Vascular Remodeling; X-Ray Microtomography

2016
Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II-Infused Apolipoprotein E-Deficient Mouse.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Bradykinin; Bradykinin B2 Receptor Antagonists; Calcium Phosphates; Dilatation, Pathologic; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Knockout; Neutrophil Activation; Osteopontin; Osteoprotegerin; Phenotype; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Signal Transduction; Time Factors; Tissue Culture Techniques

2016
Leukocyte Calpain Deficiency Reduces Angiotensin II-Induced Inflammation and Atherosclerosis But Not Abdominal Aortic Aneurysms in Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Bone Marrow Transplantation; Calcium-Binding Proteins; Calpain; Cell Adhesion; Cell Movement; Cells, Cultured; Coculture Techniques; Cysteine Proteinase Inhibitors; Diet, High-Fat; Disease Models, Animal; Endothelial Cells; Genetic Predisposition to Disease; Inflammation; Leukocytes; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Phenotype; Receptors, LDL; Whole-Body Irradiation

2016
Matricellular protein CCN3 mitigates abdominal aortic aneurysm.
    The Journal of clinical investigation, 2016, Apr-01, Volume: 126, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Elastin; Gene Deletion; Humans; MAP Kinase Signaling System; Mice; Mice, Knockout; Nephroblastoma Overexpressed Protein; Pancreatic Elastase

2016
Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors.
    Disease models & mechanisms, 2016, 05-01, Volume: 9, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Collagen; Disease Models, Animal; Disease Progression; Elastin; Enzyme Induction; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Severity of Illness Index; Up-Regulation

2016
Ursodeoxycholic Acid Attenuates Acute Aortic Dissection Formation in Angiotensin II-Infused Apolipoprotein E-Deficient Mice Associated with Reduced ROS and Increased Nrf2 Levels.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:4

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Cholagogues and Choleretics; Disease Models, Animal; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Up-Regulation; Ursodeoxycholic Acid

2016
Peroxisome Proliferator-Activated Receptor γ Level Contributes to Structural Integrity and Component Production of Elastic Fibers in the Aorta.
    Hypertension (Dallas, Tex. : 1979), 2016, Volume: 67, Issue:6

    Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Elastin; Gene Expression Regulation; Humans; Inflammation; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Middle Aged; Muscle, Smooth, Vascular; PPAR gamma

2016
Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm.
    Atherosclerosis, 2016, Volume: 249

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; CD3 Complex; Chymases; Humans; Imatinib Mesylate; Inflammation; Male; Mast Cells; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Signal Transduction

2016
Down-regulation of Fibulin-5 is associated with aortic dilation: role of inflammation and epigenetics.
    Cardiovascular research, 2016, 06-01, Volume: 110, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Binding Sites; Case-Control Studies; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Down-Regulation; Epigenesis, Genetic; Extracellular Matrix Proteins; Histone Deacetylase Inhibitors; Humans; Inflammation Mediators; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Recombinant Proteins; RNA Interference; SOX9 Transcription Factor; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha

2016
TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Rupture; Male; Mice; Mice, Inbred C57BL; Transforming Growth Factor beta

2016
Daidzein attenuates abdominal aortic aneurysm through NF-κB, p38MAPK and TGF-β1 pathways.
    Molecular medicine reports, 2016, Volume: 14, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Gene Expression; Isoflavones; Male; Matrix Metalloproteinase 2; Mice; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1

2016
Vitamin D Receptor Activation Reduces Angiotensin-II-Induced Dissecting Abdominal Aortic Aneurysm in Apolipoprotein E-Knockout Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:8

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Dissection; Apolipoproteins E; Calcitriol; Cells, Cultured; Chemokines; Chemotaxis, Leukocyte; Disease Models, Animal; Genetic Predisposition to Disease; Human Umbilical Vein Endothelial Cells; Humans; Ligands; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Phenotype; Receptors, Calcitriol; Retinoid X Receptor alpha; RNA Interference; Signal Transduction; Transfection; Vascular Endothelial Growth Factor A

2016
Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice.
    The American journal of pathology, 2016, Volume: 186, Issue:8

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cytochrome P-450 CYP1B1; Disease Models, Animal; Flow Cytometry; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Oxidative Stress; Real-Time Polymerase Chain Reaction

2016
Baicalein protects against the development of angiotensin II-induced abdominal aortic aneurysms by blocking JNK and p38 MAPK signaling.
    Science China. Life sciences, 2016, Volume: 59, Issue:9

    Topics: Angiotensin II; Animals; Antioxidants; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Elastin; Flavanones; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Protective Agents; Reactive Oxygen Species; Receptor, Angiotensin, Type 1

2016
Altered PPARγ Coactivator-1 Alpha Expression in Abdominal Aortic Aneurysm: Possible Effects on Mitochondrial Biogenesis.
    Journal of vascular research, 2016, Volume: 53, Issue:1-2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Citrate (si)-Synthase; Disease Models, Animal; Gene Expression Regulation; Humans; Mice, Knockout; Mitochondria; Mitochondrial Proton-Translocating ATPases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Voltage-Dependent Anion Channels

2016
Osteoclastogenic Differentiation of Macrophages in the Development of Abdominal Aortic Aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:9

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Calcium Phosphates; Calcium Signaling; Cell Transdifferentiation; Diphosphonates; Disease Models, Animal; Humans; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; RAW 264.7 Cells; Tartrate-Resistant Acid Phosphatase; Time Factors; Tumor Necrosis Factor-alpha; Vascular Calcification

2016
Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:9

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Biomarkers; Cholesterol; Dependovirus; Disease Models, Animal; Gene Transfer Techniques; Genetic Predisposition to Disease; Genetic Vectors; Hypercholesterolemia; Male; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mutation; Oligonucleotides, Antisense; Proprotein Convertase 9; Receptors, LDL; Species Specificity; Time Factors

2016
Silencing of hypoxia inducible factor-1α gene attenuated angiotensin Ⅱ-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice.
    Atherosclerosis, 2016, Volume: 252

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Gene Silencing; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Lentivirus; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Microcirculation; RNA Interference; RNA, Small Interfering; Signal Transduction; Time Factors; Up-Regulation

2016
Inhibition of BET bromodomain attenuates angiotensin II induced abdominal aortic aneurysm in ApoE
    International journal of cardiology, 2016, Nov-15, Volume: 223

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Azepines; Cells, Cultured; Disease Models, Animal; Extracellular Matrix; Female; Gene Expression Regulation; Humans; Male; Metalloproteases; Mice; Mice, Inbred C57BL; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA; Triazoles

2016
Hypoxia-Inducible Factor-1α in Smooth Muscle Cells Protects Against Aortic Aneurysms-Brief Report.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:11

    Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Elastic Tissue; Genetic Predisposition to Disease; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Protein-Lysine 6-Oxidase; Tropoelastin; Vascular Remodeling

2016
Heme oxygenase-1 deficiency exacerbates angiotensin II-induced aortic aneurysm in mice.
    Oncotarget, 2016, Oct-18, Volume: 7, Issue:42

    Topics: Anemia, Hemolytic; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cytokines; Growth Disorders; Heme Oxygenase-1; Iron Metabolism Disorders; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Reactive Oxygen Species

2016
B-Cell Depletion Promotes Aortic Infiltration of Immunosuppressive Cells and Is Protective of Experimental Aortic Aneurysm.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:11

    Topics: Angiotensin II; Animals; Antibodies; Antigens, CD20; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; B-Lymphocytes; Biomarkers; Cells, Cultured; Cellular Microenvironment; Coculture Techniques; Cytokines; Dendritic Cells; Disease Models, Animal; Down-Regulation; Genetic Predisposition to Disease; Immunoglobulin M; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Lymphocyte Depletion; Male; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phenotype; T-Lymphocytes, Regulatory

2016
Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm.
    Circulation research, 2016, Oct-28, Volume: 119, Issue:10

    Topics: Aging; Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortitis; Apolipoproteins E; Calcium Chloride; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; NF-kappa B; Sirtuin 1

2016
Female Mice With an XY Sex Chromosome Complement Develop Severe Angiotensin II-Induced Abdominal Aortic Aneurysms.
    Circulation, 2017, 01-24, Volume: 135, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Female; Male; Mice; Mice, Inbred C57BL; Sex Chromosomes; Vasoconstrictor Agents

2017
The Paraoxonase Gene Cluster Protects Against Abdominal Aortic Aneurysm Formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Aryldialkylphosphatase; Cells, Cultured; Disease Models, Animal; Elastin; Extracellular Matrix; Genetic Predisposition to Disease; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Multigene Family; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Phenotype; Proteolysis; Reactive Oxygen Species; Signal Transduction

2017
NOX isoforms in the development of abdominal aortic aneurysm.
    Redox biology, 2017, Volume: 11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Gene Expression Regulation; Humans; Mice; Mutation; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Polycomb Repressive Complex 1; Protein Isoforms; Superoxides; Tetrahydrofolate Dehydrogenase

2017
MicroRNA-145 Mediates the Formation of Angiotensin II-Induced Murine Abdominal Aortic Aneurysm.
    Heart, lung & circulation, 2017, Volume: 26, Issue:6

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Disease Models, Animal; Elastin; Gene Expression Regulation, Enzymologic; Lentivirus; Matrix Metalloproteinase 2; Mice; Mice, Knockout; MicroRNAs; Transduction, Genetic; Up-Regulation

2017
Bile-ated Cell Death Decreases Aortic Aneurysm Formation.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2017, Volume: 53, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Apolipoproteins; Bile; Cell Death; Endoplasmic Reticulum Stress; Mice; Taurochenodeoxycholic Acid

2017
The water channel AQP1 is expressed in human atherosclerotic vascular lesions and AQP1 deficiency augments angiotensin II-induced atherosclerosis in mice.
    Acta physiologica (Oxford, England), 2017, Volume: 220, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aquaporin 1; Coronary Artery Disease; Female; Humans; Mice; Mice, Knockout; Neovascularization, Pathologic; Vasoconstrictor Agents

2017
Angiotensin-Converting Enzyme 2 Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice.
    Human gene therapy, 2018, Volume: 29, Issue:12

    Topics: Adenoviridae; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Disease Models, Animal; Gene Expression Regulation; Genetic Vectors; Green Fluorescent Proteins; Humans; Immunohistochemistry; Macrophages; Male; Matrix Metalloproteinase 13; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Peptidyl-Dipeptidase A; Signal Transduction

2018
NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:4

    Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Dissection; Biomechanical Phenomena; Caspase 1; Cells, Cultured; Disease Models, Animal; Female; Genetic Predisposition to Disease; Glyburide; Humans; Inflammasomes; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NLR Family, Pyrin Domain-Containing 3 Protein; Phenotype; Proteolysis; Vasoconstriction

2017
Melatonin attenuates angiotensin II-induced abdominal aortic aneurysm through the down-regulation of matrix metalloproteinases.
    Oncotarget, 2017, Feb-28, Volume: 8, Issue:9

    Topics: Angiotensin II; Animals; Antioxidants; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Melatonin; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2017
Pravastatin activates activator protein 2 alpha to augment the angiotensin II-induced abdominal aortic aneurysms.
    Oncotarget, 2017, Feb-28, Volume: 8, Issue:9

    Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Anticholesteremic Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Phosphorylation; Pravastatin; Signal Transduction; Transcription Factor AP-2

2017
Effect of Bortezomib on Angiotensin Ⅱ-induced Abdominal Aortic Aneurysm in ApoE
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2017, Feb-20, Volume: 39, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bortezomib; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Phosphorylation; Proteasome Inhibitors; Random Allocation; Signal Transduction; T-Lymphocytes

2017
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:10

    Topics: Adipokines; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aortic Aneurysm, Abdominal; Apelin; Apelin Receptors; Atherosclerosis; Blood Vessels; Carrier Proteins; Cell Nucleus; Diet; Disease Models, Animal; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Nitric Oxide; Reactive Oxygen Species; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Signal Transduction; Vasoconstrictor Agents

2008
Interaction between angiotensin II, osteoprotegerin, and peroxisome proliferator-activated receptor-gamma in abdominal aortic aneurysm.
    Journal of vascular research, 2009, Volume: 46, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Humans; Interleukin-6; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Osteoprotegerin; PPAR gamma; Receptor, Angiotensin, Type 1

2009
Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice.
    Atherosclerosis, 2009, Volume: 204, Issue:2

    Topics: Acetamides; Administration, Oral; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Cholesterol; Chymases; Disease Models, Animal; Enzyme Activation; Enzyme Precursors; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Pyrimidines; Serine Proteinase Inhibitors

2009
Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan.
    International journal of molecular medicine, 2008, Volume: 22, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neutrophil Infiltration; NF-kappa B; Pancreatic Elastase; Rats; Rats, Wistar; Tetrazoles; Ultrasonography; Valine; Valsartan

2008
Extracellular matrix metalloproteinase inducer (EMMPRIN) is present in smooth muscle cells of human aneurysmal aorta and is induced by angiotensin II in vitro.
    Clinical science (London, England : 1979), 2009, May-01, Volume: 116, Issue:11

    Topics: Adult; Aged; Angiotensin II; Aortic Aneurysm, Abdominal; Aortic Dissection; Basigin; Cells, Cultured; Female; Humans; Immunohistochemistry; Male; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Up-Regulation

2009
Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II.
    Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Collagen; Collagenases; Connective Tissue; Elastin; Histocytochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout

2009
The development of abdominal aortic aneurysms in mice is enhanced by benzo(a)pyrene.
    Vascular health and risk management, 2008, Volume: 4, Issue:5

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Rupture; Benzo(a)pyrene; Disease Models, Animal; Elastic Tissue; Macrophages; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Smoking

2008
ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol, Dietary; Disease Models, Animal; Hydralazine; Hypercholesterolemia; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Receptors, LDL; Risk Factors; Time Factors

2009
Pulse wave imaging of normal and aneurysmal abdominal aortas in vivo.
    IEEE transactions on medical imaging, 2009, Volume: 28, Issue:4

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Computer Simulation; Data Interpretation, Statistical; Disease Models, Animal; Electrocardiography; Humans; Image Interpretation, Computer-Assisted; Linear Models; Mice; Mice, Inbred C57BL; Signal Processing, Computer-Assisted; Time Factors; Ultrasonography

2009
Low-level laser irradiation inhibits abdominal aortic aneurysm progression in apolipoprotein E-deficient mice.
    Cardiovascular research, 2009, Sep-01, Volume: 83, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Dilatation, Pathologic; Humans; Low-Level Light Therapy; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Ultrasonography

2009
Rosiglitazone reduces the development and rupture of experimental aortic aneurysms.
    Circulation, 2009, Jun-23, Volume: 119, Issue:24

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Blood Glucose; Body Weight; Cholesterol; Disease Models, Animal; E-Selectin; Humans; Hypercholesterolemia; Hypoglycemic Agents; Interleukin-6; Mice; Mice, Knockout; PPAR gamma; Receptors, Angiotensin; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2009
Involvement of vascular angiotensin II-forming enzymes in the progression of aortic abdominal aneurysms in angiotensin II- infused ApoE-deficient mice.
    Journal of atherosclerosis and thrombosis, 2009, Volume: 16, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Benzimidazoles; Biphenyl Compounds; Chymases; Disease Progression; Lisinopril; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Tetrazoles

2009
Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm.
    BMC genomics, 2009, Jul-06, Volume: 10

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Gene Expression; Genome-Wide Association Study; Humans; Male; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Up-Regulation

2009
Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice.
    PloS one, 2009, Jul-07, Volume: 4, Issue:7

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Chemokines; Cytokines; Mice; Mice, Knockout; Receptors, LDL; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction

2009
Obesity promotes inflammation in periaortic adipose tissue and angiotensin II-induced abdominal aortic aneurysm formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:10

    Topics: Adipose Tissue; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Cell Movement; Cytokines; Dietary Fats; Inflammation; Insulin Resistance; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; Systole

2009
Assessment of macrophage infiltration in a murine model of abdominal aortic aneurysm.
    Journal of magnetic resonance imaging : JMRI, 2009, Volume: 30, Issue:2

    Topics: Analysis of Variance; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Contrast Media; Dextrans; Disease Models, Animal; Ferrosoferric Oxide; Image Processing, Computer-Assisted; Inflammation; Infusion Pumps, Implantable; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice

2009
Inhibition of soluble epoxide hydrolase attenuated atherosclerosis, abdominal aortic aneurysm formation, and dyslipidemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9

    Topics: Administration, Oral; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Biological Availability; Carotid Arteries; Cholesterol; Disease Models, Animal; Down-Regulation; Dyslipidemias; Enzyme Inhibitors; Epoxide Hydrolases; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-1alpha; Interleukin-6; Interleukin-8; Ligation; Male; Mice; Mice, Knockout; Vascular Cell Adhesion Molecule-1

2009
Simvastatin inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-knockout mice: possible role of ERK.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Benzamides; Blood Pressure; Blotting, Western; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; MAP Kinase Kinase Kinase 3; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Random Allocation; Reference Values; Renin-Angiotensin System; Simvastatin

2009
Understanding abdominal aortic aneurysm.
    The New England journal of medicine, 2009, Sep-10, Volume: 361, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cyclophilin A; Humans; Hyperlipidemias; Inflammation; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species

2009
Cathepsin K gene disruption does not affect murine aneurysm formation.
    Atherosclerosis, 2010, Volume: 209, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cathepsin C; Cathepsin K; Cathepsins; Collagen; Granulocytes; Lymphocyte Count; Macrophages; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; T-Lymphocytes

2010
In vivo serial assessment of aortic aneurysm formation in apolipoprotein E-deficient mice via MRI.
    Circulation. Cardiovascular imaging, 2008, Volume: 1, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Doxycycline; Magnetic Resonance Imaging; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Knockout

2008
Peroxisome proliferator-activated receptor ligands reduce aortic dilatation in a mouse model of aortic aneurysm.
    Atherosclerosis, 2010, Volume: 210, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Fenofibrate; Immunohistochemistry; Ligands; Macrophages; Male; Mice; Osteopontin; Peroxisome Proliferator-Activated Receptors; Pioglitazone; Thiazolidinediones; Up-Regulation

2010
Perforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysm.
    The American journal of pathology, 2010, Volume: 176, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Extracellular Space; Fibrillin-1; Fibrillins; Granzymes; Humans; Immune System; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Perforin; Protein Processing, Post-Translational; Tissue Distribution

2010
Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation.
    Atherosclerosis, 2010, Volume: 210, Issue:1

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Benzopyrans; Carboxylic Acids; Chemotaxis; Disease Progression; Immunohistochemistry; Leukotriene B4; Male; Mice; Ultrasonography

2010
Effects of caspase inhibitor on angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Caspase Inhibitors; Caspases; Cells, Cultured; Chemokine CCL2; Chemotaxis; Culture Media, Conditioned; Disease Models, Animal; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protease Inhibitors; Quinolines; Severity of Illness Index; Time Factors

2010
TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:2

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm, Abdominal; Disease Progression; Inflammation; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Transforming Growth Factor beta; Ultrasonography

2010
High fat diet containing cholesterol induce aortic aneurysm through recruitment and proliferation of circulating agranulocytes in apoE knock out mice model.
    Journal of thrombosis and thrombolysis, 2010, Volume: 30, Issue:2

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Apolipoproteins E; Biomarkers; Blood Pressure; Cell Movement; Cell Proliferation; Chemokine CCL2; Cholesterol, Dietary; Disease Models, Animal; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation; Granulocytes; Hypercholesterolemia; Intercellular Adhesion Molecule-1; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Time Factors; Vascular Cell Adhesion Molecule-1; Weight Gain

2010
Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:5

    Topics: Aminopropionitrile; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Aortic Dissection; Blood Pressure; Desoxycorticosterone; Humans; Hypertension; Male; Mice; Mice, Inbred C57BL; Mineralocorticoids; Protein-Lysine 6-Oxidase

2010
Complement regulator CD59 protects against angiotensin II-induced abdominal aortic aneurysms in mice.
    Circulation, 2010, Mar-23, Volume: 121, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; CD59 Antigens; Complement Membrane Attack Complex; Complement System Proteins; Female; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Models, Animal; NF-kappa B; Signal Transduction; Transcription Factor AP-1

2010
Weight loss in obese C57BL/6 mice limits adventitial expansion of established angiotensin II-induced abdominal aortic aneurysms.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Connective Tissue; Dietary Fats; Disease Models, Animal; Disease Progression; Endoglin; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Obesity; RNA, Messenger; Weight Loss

2010
Loss of STAT1 is associated with increased aortic rupture in an experimental model of aortic dissection and aneurysm formation.
    Journal of vascular surgery, 2010, Volume: 51, Issue:4

    Topics: Aged; Analysis of Variance; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Dissection; Aortic Rupture; Apolipoproteins E; Chi-Square Distribution; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Mice; Mice, Knockout; Phosphorylation; RNA, Messenger; Severity of Illness Index; Sex Factors; STAT1 Transcription Factor; Time Factors

2010
Total lymphocyte deficiency attenuates AngII-induced atherosclerosis in males but not abdominal aortic aneurysms in apoE deficient mice.
    Atherosclerosis, 2010, Volume: 211, Issue:2

    Topics: Aneurysm; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; B-Lymphocytes; Female; Gene Expression Regulation; Genotype; Hypercholesterolemia; Lymphocytes; Male; Mice; T-Lymphocytes

2010
Vascular endothelial growth factor enhances angiotensin II-induced aneurysm formation in apolipoprotein E-deficient mice.
    Journal of vascular surgery, 2010, Volume: 52, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Body Weight; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Gene Expression Regulation, Enzymologic; Humans; Infusion Pumps, Implantable; Injections, Intraperitoneal; Magnetic Resonance Angiography; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Recombinant Proteins; Time Factors; Vascular Endothelial Growth Factor A

2010
Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice.
    The American journal of pathology, 2010, Volume: 177, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cell Adhesion Molecules; Cell Proliferation; Cystatin C; Humans; Inflammation; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle

2010
Hyperglycemia limits experimental aortic aneurysm progression.
    Journal of vascular surgery, 2010, Volume: 52, Issue:4

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Hypoglycemic Agents; Insulin; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Pancreatic Elastase; Peritonitis; Thioglycolates; Time Factors; Ultrasonography; Vascular Endothelial Growth Factor A

2010
Efficacy of simvastatin in reducing aortic dilatation in mouse models of abdominal aortic aneurysm.
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:5-6

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Lipids; Male; Mice; Mice, Transgenic; Plaque, Atherosclerotic; Receptors, Lipoprotein; Simvastatin

2010
Group X secretory phospholipase A(2) augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice.
    Atherosclerosis, 2011, Volume: 214, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Group X Phospholipases A2; Humans; Inflammation; Interleukins; Metalloproteases; Mice; Mice, Inbred C57BL; Mice, Transgenic

2011
In vivo quantification of murine aortic cyclic strain, motion, and curvature: implications for abdominal aortic aneurysm growth.
    Journal of magnetic resonance imaging : JMRI, 2010, Volume: 32, Issue:4

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Elastin; Genotype; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motion; Time Factors

2010
Cigarette smoke enhances abdominal aortic aneurysm formation in angiotensin II-treated apolipoprotein E-deficient mice.
    Toxicology letters, 2010, Dec-15, Volume: 199, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Body Weight; Disease Models, Animal; Male; Matrix Metalloproteinases; Mice; Nicotiana; Smoke; Tissue Inhibitor of Metalloproteinases

2010
Influences of aortic motion and curvature on vessel expansion in murine experimental aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomechanical Phenomena; Blood Pressure; Disease Progression; Elastin; Hypertension; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Models, Cardiovascular; Ultrasonography

2011
Telomerase deficiency in bone marrow-derived cells attenuates angiotensin II-induced abdominal aortic aneurysm formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Bone Marrow Transplantation; Cell Movement; Cells, Cultured; Elastin; Genotype; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Models, Animal; Receptors, LDL; Telomerase; Telomere

2011
Deletion of EP4 on bone marrow-derived cells enhances inflammation and angiotensin II-induced abdominal aortic aneurysm formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Bone Marrow Cells; Bone Marrow Transplantation; Chemokine CCL2; Elastin; Female; Gene Deletion; Hyperlipidemias; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Receptors, LDL; Receptors, Prostaglandin E, EP4 Subtype; Risk Factors

2011
Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Autoradiography; Contrast Media; Disease Models, Animal; Female; Flow Cytometry; Fluorodeoxyglucose F18; Macrophages; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Reproducibility of Results; Splenectomy; Time Factors; X-Ray Microtomography

2011
Parsing aortic aneurysms: more surprises.
    Circulation research, 2011, Mar-04, Volume: 108, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cell Communication; Disease Models, Animal; Endothelial Cells; Incidence; Macrophages; Mice; Mice, Knockout; Mice, Mutant Strains; Mutation; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1; Receptors, LDL

2011
Statins exert differential effects on angiotensin II-induced atherosclerosis, but no benefit for abdominal aortic aneurysms.
    Atherosclerosis, 2011, Volume: 217, Issue:1

    Topics: Angiotensin II; Animal Feed; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Atorvastatin; Blood Pressure; Fluorobenzenes; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides

2011
Catalase overexpression in aortic smooth muscle prevents pathological mechanical changes underlying abdominal aortic aneurysm formation.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:2

    Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Blood Pressure; Catalase; Collagen; Disease Models, Animal; Elastin; Hydrogen Peroxide; Mice; Mice, Knockout; Mice, Transgenic; Stress, Mechanical; Time Factors; Up-Regulation

2011
An integrated framework to quantitatively link mouse-specific hemodynamics to aneurysm formation in angiotensin II-infused ApoE -/- mice.
    Annals of biomedical engineering, 2011, Volume: 39, Issue:9

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Computer Simulation; Hemodynamics; Hydrodynamics; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Ultrasonography; Vasoconstrictor Agents

2011
Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm.
    Physiological genomics, 2011, Sep-08, Volume: 43, Issue:17

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis

2011
Prolonged infusion of angiotensin II in apoE(-/-) mice promotes macrophage recruitment with continued expansion of abdominal aortic aneurysm.
    The American journal of pathology, 2011, Volume: 179, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Macrophages; Male; Mice; Mice, Inbred C57BL; Vasoconstrictor Agents

2011
Chinese red yeast rice attenuates the development of angiotensin II-induced abdominal aortic aneurysm and atherosclerosis.
    The Journal of nutritional biochemistry, 2012, Volume: 23, Issue:6

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Biological Products; Chemokine CCL2; Cholesterol; Inflammation; Interleukin-1alpha; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Plant Extracts; Tunica Intima

2012
Urokinase-type plasminogen activator deficiency in bone marrow-derived cells augments rupture of angiotensin II-induced abdominal aortic aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:12

    Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bone Marrow Cells; Disease Models, Animal; Hypercholesterolemia; Incidence; Leukocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL; Receptors, Urokinase Plasminogen Activator; Urokinase-Type Plasminogen Activator

2011
Development of angiotensin II-induced abdominal aortic aneurysms is independent of catalase in mice.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:6

    Topics: Aldehydes; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Blood Pressure; Body Weight; Catalase; Cholesterol; Lipid Peroxidation; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Oxidative Stress

2011
Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm.
    Cell death & disease, 2011, Sep-08, Volume: 2

    Topics: Acute-Phase Proteins; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Collagen; Decorin; Disease Models, Animal; Granzymes; Mice; Mice, Knockout; Protein Processing, Post-Translational; Recombinant Proteins; Serpins

2011
Polychlorinated biphenyl 77 augments angiotensin II-induced atherosclerosis and abdominal aortic aneurysms in male apolipoprotein E deficient mice.
    Toxicology and applied pharmacology, 2011, Nov-15, Volume: 257, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Drug Synergism; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Polychlorinated Biphenyls; Real-Time Polymerase Chain Reaction

2011
MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through Toll-like receptors 2 and 4.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:12

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Leukocytes; Male; Mice; Mice, Knockout; Myeloid Differentiation Factor 88; Receptors, LDL; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4

2011
Calpain inhibition attenuates angiotensin II-induced abdominal aortic aneurysms and atherosclerosis in low-density lipoprotein receptor-deficient mice.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Blotting, Western; Calpain; Cysteine Proteinase Inhibitors; Diet, High-Fat; Disease Models, Animal; Hypercholesterolemia; Male; Mice; Mice, Knockout; Receptors, LDL; Sulfonamides

2012
Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acid.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Biopterins; Blood Pressure; Disease Models, Animal; Folic Acid; Genetic Therapy; GTP Cyclohydrolase; Hypertension; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Mutant Strains; Nitric Oxide; Nitric Oxide Synthase Type III; Tetrahydrofolate Dehydrogenase; Vasoconstrictor Agents; Vitamin B Complex

2012
The controversial role of the urokinase system in abdominal aortic aneurysm formation and rupture.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:12

    Topics: Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Bone Marrow Cells; Urokinase-Type Plasminogen Activator

2011
Deficiency of receptor-associated protein attenuates angiotensin II-induced atherosclerosis in hypercholesterolemic mice without influencing abdominal aortic aneurysms.
    Atherosclerosis, 2012, Volume: 220, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Bone Marrow Cells; Bone Marrow Transplantation; Cells, Cultured; Cholesterol; Disease Models, Animal; Hypercholesterolemia; LDL-Receptor Related Protein-Associated Protein; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, LDL; Tumor Suppressor Proteins

2012
Syndecan-1 displays a protective role in aortic aneurysm formation by modulating T cell-mediated responses.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bone Marrow Transplantation; CD4-Positive T-Lymphocytes; Chemokines; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Syndecan-1

2012
The effects of angiotensin II on the coupled microstructural and biomechanical response of C57BL/6 mouse aorta.
    Journal of biomechanics, 2012, Mar-15, Volume: 45, Issue:5

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Collagen; Disease Models, Animal; Extracellular Matrix; Mice; Mice, Inbred C57BL

2012
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.
    The Journal of clinical investigation, 2012, Volume: 122, Issue:2

    Topics: Adolescent; Aged; Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Disease Models, Animal; Disease Progression; Elastin; Gene Expression; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Middle Aged; Pancreatic Elastase; Protein Isoforms; Swine; Young Adult

2012
A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation.
    Cardiovascular research, 2012, Apr-01, Volume: 94, Issue:1

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm, Abdominal; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Chemotaxis, Leukocyte; Disease Models, Animal; Dose-Response Relationship, Drug; Lymphocyte Activation; Macrophage Activation; Male; Mice; Mice, Knockout; Peptides; Platelet Endothelial Cell Adhesion Molecule-1; Receptors, Antigen, T-Cell; T-Lymphocytes; Time Factors

2012
MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion.
    Science translational medicine, 2012, Feb-22, Volume: 4, Issue:122

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Cell Proliferation; Gene Expression Profiling; Humans; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; MicroRNAs; Nicotine; Pancreatic Elastase; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Sus scrofa; Up-Regulation

2012
CD31: beyond a marker for endothelial cells.
    Cardiovascular research, 2012, Apr-01, Volume: 94, Issue:1

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm, Abdominal; Aortic Diseases; Atherosclerosis; Male; Peptides; Platelet Endothelial Cell Adhesion Molecule-1

2012
Benzo[a]pyrene potentiates the pathogenesis of abdominal aortic aneurysms in apolipoprotein E knockout mice.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 29, Issue:1-2

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Benzo(a)pyrene; Cyclophilin A; Inflammation; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Tumor Necrosis Factor-alpha

2012
In vivo imaging of macrophages during the early-stages of abdominal aortic aneurysm using high resolution MRI in ApoE mice.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Cytokines; Dextrans; Disease Models, Animal; Humans; Lipids; Macrophages; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phagocytosis

2012
Interleukin-5 is a potential mediator of angiotensin II-induced aneurysm formation in apolipoprotein E knockout mice.
    The Journal of surgical research, 2012, Volume: 178, Issue:1

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cells, Cultured; Interleukin-10; Interleukin-5; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Th1 Cells; Th2 Cells; Vasculitis; Vasoconstrictor Agents

2012
Inhibition of development of abdominal aortic aneurysm by glycolysis restriction.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Calcium Chloride; Cell Adhesion; Cell Proliferation; Cell Survival; Deoxyglucose; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Fluorodeoxyglucose F18; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Glycolysis; Humans; Inflammation Mediators; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Positron-Emission Tomography; Radiopharmaceuticals; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells; Up-Regulation

2012
Transient exposure of neonatal female mice to testosterone abrogates the sexual dimorphism of abdominal aortic aneurysms.
    Circulation research, 2012, May-25, Volume: 110, Issue:11

    Topics: Age Factors; Angiotensin II; Animals; Animals, Newborn; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Female; Hydrogen Peroxide; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1; Receptors, LDL; Risk Factors; RNA, Messenger; Sex Characteristics; Sex Factors; Testosterone Propionate; Up-Regulation

2012
Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo.
    Nature medicine, 2012, Volume: 18, Issue:6

    Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Humans; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Nicotine; Phosphorylation; Reactive Oxygen Species; Smoking; Transcription Factor AP-2

2012
Inhibition of EP4 signaling attenuates aortic aneurysm formation.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Aged; Aged, 80 and over; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Line; Disease Models, Animal; Enzyme Activation; Female; Gene Deletion; Humans; Interleukin-6; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Mice; Mice, Knockout; Middle Aged; Myocytes, Smooth Muscle; Naphthalenes; Phenylbutyrates; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Tissue Culture Techniques; Up-Regulation

2012
Prostaglandin receptor EP4 in abdominal aortic aneurysms.
    The American journal of pathology, 2012, Volume: 181, Issue:1

    Topics: Adult; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Rupture; Atherosclerosis; Cyclooxygenase 2; Drug Evaluation, Preclinical; Female; Gene Knockdown Techniques; Humans; Macrophages; Male; Mice; Mice, Knockout; Middle Aged; Naphthalenes; Phenylbutyrates; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Ultrasonography

2012
Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model.
    The American journal of pathology, 2012, Volume: 181, Issue:2

    Topics: Angiotensin II; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apoptosis; Azo Compounds; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Endothelial Cells; Fenofibrate; Inflammation; Kidney; Lipoproteins, HDL; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Receptors, Lysosphingolipid; Sphingosine; Treatment Outcome; Up-Regulation

2012
Group V secretory phospholipase A2 enhances the progression of angiotensin II-induced abdominal aortic aneurysms but confers protection against angiotensin II-induced cardiac fibrosis in apoE-deficient mice.
    The American journal of pathology, 2012, Volume: 181, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Apoptosis; Collagen; Disease Progression; Fibrosis; Group V Phospholipases A2; Immunohistochemistry; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Prostaglandins

2012
Chemokine (C-C motif) receptor 2 mediates mast cell migration to abdominal aortic aneurysm lesions in mice.
    Cardiovascular research, 2012, Dec-01, Volume: 96, Issue:3

    Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cell Proliferation; Cells, Cultured; Chemotaxis; Disease Models, Animal; Elastin; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Proto-Oncogene Proteins c-kit; Receptors, CCR2

2012
Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice.
    Cardiovascular research, 2012, Dec-01, Volume: 96, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cathepsin K; Cathepsins; CD3 Complex; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; T-Lymphocytes; Time Factors

2012
The role of lysyl oxidase family members in the stabilization of abdominal aortic aneurysms.
    American journal of physiology. Heart and circulatory physiology, 2012, Oct-15, Volume: 303, Issue:8

    Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Diet, High-Fat; Disease Models, Animal; Extracellular Matrix; Extracellular Matrix Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Protein-Lysine 6-Oxidase; RNA, Messenger; Vasoconstrictor Agents

2012
Low level laser arrests abdominal aortic aneurysm by collagen matrix reinforcement in apolipoprotein E-deficient mice.
    Lasers in surgery and medicine, 2012, Volume: 44, Issue:8

    Topics: Adventitia; Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Low-Level Light Therapy; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Vasoconstrictor Agents

2012
Effectiveness of cyclooxygenase-2 inhibition in limiting abdominal aortic aneurysm progression in mice correlates with a differentiated smooth muscle cell phenotype.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Biomarkers; Celecoxib; Cell Differentiation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Pyrazoles; RNA, Messenger; Severity of Illness Index; Sulfonamides; Time Factors

2012
Importance of endothelial NF-κB signalling in vascular remodelling and aortic aneurysm formation.
    Cardiovascular research, 2013, Jan-01, Volume: 97, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Disease Models, Animal; Endothelium, Vascular; Femoral Artery; Humans; Hyperplasia; I-kappa B Proteins; Inflammation Mediators; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Signal Transduction; Vascular System Injuries

2013
Elevation of plasma high-density lipoproteins inhibits development of experimental abdominal aortic aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:11

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Autophagy; Calcium Chloride; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Hypercholesterolemia; Injections, Subcutaneous; JNK Mitogen-Activated Protein Kinases; Lipoproteins, HDL; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Time Factors; Up-Regulation

2012
Doxycycline does not influence established abdominal aortic aneurysms in angiotensin II-infused mice.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Administration, Oral; Angiotensin II; Animals; Anti-Bacterial Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Blood Pressure; Cholesterol; Diet, High-Fat; Disease Models, Animal; Doxycycline; Infusion Pumps, Implantable; Male; Mice; Mice, Knockout; Receptors, LDL; Vasoconstrictor Agents

2012
Aneurysm prevention: keep the cat out of the bag.
    Cardiovascular research, 2012, Dec-01, Volume: 96, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cathepsins; Male

2012
Inhibition of Notch1 signaling reduces abdominal aortic aneurysm in mice by attenuating macrophage-mediated inflammation.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:12

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteritis; Dipeptides; Disease Models, Animal; Haploinsufficiency; Humans; Macrophages; Male; Mice; Mice, Knockout; Receptor, Notch1; Signal Transduction

2012
Loss of Timp3 gene leads to abdominal aortic aneurysm formation in response to angiotensin II.
    The Journal of biological chemistry, 2012, Dec-28, Volume: 287, Issue:53

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Female; Hepatitis A Virus Cellular Receptor 2; Humans; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Virus

2012
Locally applied leptin induces regional aortic wall degeneration preceding aneurysm formation in apolipoprotein E-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Delayed-Action Preparations; Dilatation, Pathologic; Disease Models, Animal; Humans; Leptin; Macrophages; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Leptin; RNA, Messenger; Time Factors; Transforming Growth Factor beta; Ultrasonography

2013
Clopidogrel, a platelet P2Y12 receptor inhibitor, reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Platelets; Blood Pressure Determination; Clopidogrel; Cytokines; Immunoenzyme Techniques; Inflammation; Macrophages, Peritoneal; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Aggregation Inhibitors; Reactive Oxygen Species; Receptors, Purinergic P2Y12; Ticlopidine; Vasculitis; Vasoconstrictor Agents

2012
Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:4

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cells, Cultured; Chemokine CCL5; Chemotaxis, Leukocyte; Disease Models, Animal; Disease Progression; Injections, Intravenous; Leukocytes; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Oligopeptides; Pancreatic Elastase; Platelet Factor 4; Receptors, CCR5; Time Factors

2013
Overexpression of SOCS3 in T lymphocytes leads to impaired interleukin-17 production and severe aortic aneurysm formation in mice--brief report.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:3

    Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aortic Aneurysm, Abdominal; Aortic Rupture; Bone Marrow Transplantation; Cells, Cultured; Disease Models, Animal; Genotype; Interleukin-17; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neutrophils; Phenotype; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Th17 Cells; Time Factors; Transforming Growth Factor beta; Up-Regulation; Whole-Body Irradiation

2013
Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:4

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Movement; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Everolimus; Flow Cytometry; Infusion Pumps, Implantable; Infusions, Subcutaneous; Interferon-gamma; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Protein Kinase Inhibitors; Receptor, Macrophage Colony-Stimulating Factor; Receptors, CCR2; Sirolimus; TOR Serine-Threonine Kinases

2013
Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs.
    Physiological genomics, 2002, Oct-02, Volume: 11, Issue:1

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Arteriosclerosis; Cell Adhesion Molecules; Chemokines; Cyclooxygenase 2; Down-Regulation; Gene Expression Regulation; Isoenzymes; Male; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors

2002
Angiotensin II injures the arterial wall causing increased aortic stiffening in apolipoprotein E-deficient mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 283, Issue:6

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Blood Pressure; Carotid Arteries; Collagen; Drug Administration Schedule; Elasticity; Elastin; Endothelium, Vascular; Male; Mice; Mice, Knockout; Nitroprusside

2002
Urokinase-type plasminogen activator plays a critical role in angiotensin II-induced abdominal aortic aneurysm.
    Circulation research, 2003, Mar-21, Volume: 92, Issue:5

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; In Situ Hybridization; Interleukin-6; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger; Urokinase-Type Plasminogen Activator

2003
Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Mar-01, Volume: 23, Issue:3

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Arteriosclerosis; Cholesterol; Doxycycline; Hyperlipidemias; Lipoproteins; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Mutant Strains

2003
17 Beta-estradiol attenuates development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Sep-01, Volume: 23, Issue:9

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Disease Models, Animal; Estradiol; Female; Inflammation; Male; Mice

2003
Near-infrared spectrometry of abdominal aortic aneurysm in the ApoE-/- mouse.
    Analytical chemistry, 2003, Jul-15, Volume: 75, Issue:14

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Calibration; Collagen; Elastin; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Spectroscopy, Near-Infrared

2003
Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice.
    The Journal of clinical investigation, 2003, Volume: 112, Issue:9

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Cell Movement; Cell Survival; Chemokine CCL2; Cytokines; Gene Expression Regulation; Leukocytes; Macrophages; Mice; Mice, Inbred C57BL; Osteopontin; Receptors, CCR2; Receptors, Chemokine; RNA, Messenger; Sialoglycoproteins

2003
Orchidectomy, but not ovariectomy, regulates angiotensin II-induced vascular diseases in apolipoprotein E-deficient mice.
    Endocrinology, 2004, Volume: 145, Issue:8

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Female; Gonadal Steroid Hormones; Male; Mice; Mice, Inbred C57BL; Orchiectomy; Ovariectomy; Sex Characteristics

2004
Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Bone Marrow; Bone Marrow Transplantation; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Monocytes; Receptors, CCR2; Receptors, Chemokine

2004
Aldosterone does not mediate angiotensin II-induced atherosclerosis and abdominal aortic aneurysms.
    British journal of pharmacology, 2005, Volume: 144, Issue:3

    Topics: Aldosterone; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Blood Pressure; Body Weight; Cholesterol; Diuretics; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Organ Size; Spironolactone

2005
Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis.
    Circulation, 2005, May-03, Volume: 111, Issue:17

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Endothelium, Vascular; Extracellular Matrix; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Protease Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases

2005
Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:8

    Topics: Angiotensin II; Animals; Antioxidants; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Blood Pressure; Dinoprost; Hyperlipidemias; Lipids; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Mutant Strains; Osteopontin; Oxidative Stress; Sialoglycoproteins; Vasoconstrictor Agents; Vitamin E

2005
Association of osteoprotegerin with human abdominal aortic aneurysm progression.
    Circulation, 2005, Jun-14, Volume: 111, Issue:23

    Topics: Adult; Aged; Angiotensin II; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Biopsy; Biphenyl Compounds; Cell Proliferation; Cells, Cultured; Disease Progression; Gene Expression Regulation, Enzymologic; Glycoproteins; Humans; Irbesartan; Male; Matrix Metalloproteinase 9; Middle Aged; Muscle, Smooth, Vascular; Osteoprotegerin; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Tetrazoles; Ultrasonography

2005
Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Hypercholesterolemia; Male; Mice; Mice, Inbred C57BL; Prostaglandin D2; Pyrazoles; Sulfonamides

2006
COX-2 in cardiovascular disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:5

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Epoprostenol; Mice; Pyrazoles; Sulfonamides

2006
Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice.
    Circulation, 2006, Aug-01, Volume: 114, Issue:5

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Cholesterol; Gene Deletion; Gene Expression Regulation; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; NADPH Oxidases; Oxidative Stress; Phenylephrine; Superoxides; Triglycerides

2006
Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography.
    Journal of vascular surgery, 2006, Volume: 44, Issue:2

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Apolipoproteins E; Dilatation, Pathologic; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reproducibility of Results; Ultrasonography

2006
Genetic deficiency of cyclooxygenase-2 attenuates abdominal aortic aneurysm formation in mice.
    Cardiovascular research, 2007, Jan-01, Volume: 73, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Chemokine CCL2; Chemokine CCL4; Chemotaxis, Leukocyte; Cyclooxygenase 2; Immunohistochemistry; Macrophage Inflammatory Proteins; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Models, Animal; RNA, Messenger; Time Factors

2007
Interferon-beta attenuates angiotensin II-accelerated atherosclerosis and vascular remodeling in apolipoprotein E deficient mice.
    Atherosclerosis, 2008, Volume: 197, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Carotid Artery, Common; Cell Division; Drug Interactions; Foam Cells; Immunologic Factors; Interferon-beta; Ligation; Male; Mice; Mice, Mutant Strains; Tunica Intima; Vasoconstrictor Agents

2008
The significance of chymase in the progression of abdominal aortic aneurysms in dogs.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:4

    Topics: Acetamides; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Count; Chymases; Disease Models, Animal; Disease Progression; Dogs; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neutrophils; Pyrimidines; Tunica Media; Ultrasonography

2007
Angiotensin II-induced abdominal aortic aneurysm occurs independently of the 5-lipoxygenase pathway in apolipoprotein E-deficient mice.
    Prostaglandins & other lipid mediators, 2007, Volume: 84, Issue:1-2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arachidonate 5-Lipoxygenase; Blood Pressure; Chemokine CCL4; Indoles; Inflammation; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Genetic; Quinolines; Time Factors

2007
A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice.
    Journal of vascular research, 2008, Volume: 45, Issue:2

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Immunohistochemistry; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protease Inhibitors; Rats; Sulfonamides

2008
Overexpression of PAI-1 prevents the development of abdominal aortic aneurysm in mice.
    Gene therapy, 2008, Volume: 15, Issue:3

    Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cytomegalovirus; Fibrosis; Gene Expression; Genetic Therapy; Genetic Vectors; Luciferases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Plasminogen Activator Inhibitor 1; Transduction, Genetic; Urokinase-Type Plasminogen Activator

2008
Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation.
    Circulation, 2008, Mar-11, Volume: 117, Issue:10

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Hyperlipidemias; Intramolecular Oxidoreductases; Male; Mice; Mice, Knockout; Oxidative Stress; Prostaglandin-E Synthases; Prostaglandins; Receptors, LDL; Up-Regulation

2008
Androgen increases AT1a receptor expression in abdominal aortas to promote angiotensin II-induced AAAs in apolipoprotein E-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:7

    Topics: Androgens; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Dihydrotestosterone; Disease Models, Animal; Drug Implants; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orchiectomy; Ovariectomy; Receptor, Angiotensin, Type 1; RNA, Messenger; Sex Factors; Time Factors; Up-Regulation

2008
Angiotensin II, atherosclerosis, and aortic aneurysms.
    The Journal of clinical investigation, 2000, Volume: 105, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Arteriosclerosis; Mice; Reactive Oxygen Species

2000
Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice.
    The Journal of clinical investigation, 2000, Volume: 105, Issue:11

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Female; Lymphocytes; Macrophages; Mice; Mice, Inbred C57BL

2000
Chronic angiotensin II infusion promotes atherogenesis in low density lipoprotein receptor -/- mice.
    Annals of the New York Academy of Sciences, 1999, Nov-18, Volume: 892

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Arteriosclerosis; Blood Pressure; Cholesterol; Infusions, Intravenous; Lipoproteins, LDL; Mice; Mice, Inbred C57BL; Severity of Illness Index; Vasoconstrictor Agents

1999
Angiotensin II increases urokinase-type plasminogen activator expression and induces aneurysm in the abdominal aorta of apolipoprotein E-deficient mice.
    The American journal of pathology, 2001, Volume: 159, Issue:4

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; In Vitro Techniques; Interleukin-6; Mice; Mice, Knockout; Reference Values; Time Factors; Ultrasonography; Urokinase-Type Plasminogen Activator

2001
Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Drug Synergism; Female; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Severity of Illness Index

2001