angiotensin ii has been researched along with Aneurysm, Aortic in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (4.35) | 18.7374 |
| 1990's | 2 (2.17) | 18.2507 |
| 2000's | 11 (11.96) | 29.6817 |
| 2010's | 55 (59.78) | 24.3611 |
| 2020's | 20 (21.74) | 2.80 |
| Authors | Studies |
|---|---|
| Bian, H; Cho, K; Han, N; Jiang, B; Li, X; Wang, L; Wang, Y; Wu, P; Yin, J; Zhang, X; Zhang, Y | 1 |
| Bajo, MA; Briones, AM; Cannata-Ortiz, P; Egido, J; Esteban, V; Falke, LL; Goldschmeding, R; Mallat, Z; Orejudo, M; Ortiz, A; Rayego-Mateos, S; Rodrigues-Díez, R; Rodrigues-Díez, RR; Ruiz-Ortega, M; Steffensen, LB; Tejera-Muñoz, A | 1 |
| Daugherty, A; Hada, Y; Shikata, K; Subramanian, V; Takatsuka, T; Takeuchi, H; Uchida, HA; Umebayashi, R; Wada, J | 1 |
| Dohgu, S; Inada, K; Koga, M; Yamada, A; Yamauchi, A | 1 |
| Chen, BY; Du, LJ; Duan, SZ; Jia, F; Li, RG; Lin, WZ; Liu, T; Liu, Y; Lu, H; Shao, S; Sun, JY; Wang, YL; Zhang, WC; Zhou, LJ; Zhu, H | 1 |
| Atchison, DK; Bergin, IL; Bitzer, M; Converso-Baran, K; Ganesh, SK; Hartman, JR; Ju, W; O'Connor, CL; Smrcka, AV; Wang, Y; Zhang, H | 1 |
| Ding, XJ; Liang, ES; Liu, X; Liu, Y; Yang, RX | 1 |
| Desnoyer, R; Harford, TJ; Jara, ZP; Karnik, SS; Kumar, A; Singh, KD; Srinivasan, D | 1 |
| Cai, H; Huang, K; Wu, Y; Youn, JY; Zhang, Y | 1 |
| Abudupataer, M; Lai, H; Li, J; Ming, Y; Wang, C; Xiang, B; Yin, X; Zhu, K | 1 |
| Ashida, S; Mutsuga, M; Narita, Y; Tokoro, M; Usui, A; Yamawaki-Ogata, A | 1 |
| Cheng, Z; Fu, XM; Li, JM; Liao, XB; Wu, QY; Wu, Y; Zhao, Y; Zhou, XM; Zhou, YZ | 1 |
| Chen, H; Hu, P; Liu, J; Que, Y; Shu, X; Tong, X; Wang, L; Wang, S; Xiong, R | 1 |
| Chen, H; Chen, L; Hu, P; Li, S; Que, Y; Seta, F; Tong, X; Xiao, L; Xiong, R; Yu, W | 1 |
| Arshad, M; Böckler, D; Dihlmann, S; Hakimi, M; Wortmann, M | 1 |
| Chuma, M; Goda, M; Hosooka, M; Ishizawa, K; Izawa-Ishizawa, Y; Kagimoto, Y; Kondo, M; Matsuoka, R; Saito, N; Takechi, K; Tsuneyama, K; Yagi, K; Zamami, Y | 1 |
| Arnaoutakis, GJ; Chun, C; Jiang, Z; Pruitt, EY; Qi, X; Saldarriaga, L; Upchurch, GR; Wang, F | 1 |
| Annapragada, AV; Devkota, L; Ghaghada, KB; LeMaire, SA; Ren, P; Shen, YH; Starosolski, Z; Stupin, IV; Tanifum, EA; Vela, D; Zhang, C | 1 |
| Eguchi, S; Elliott, KJ; Kawai, T; Scalia, R | 1 |
| Althagafi, MG; Besla, R; Byrne, JS; Chen, Y; Cybulsky, MI; Li, A; Lindsay, T; Pacheco, S; Robbins, CS; Ulndreaj, A | 1 |
| Bustelo, XR; Cámara, JA; Cañamero, M; de Cárcer, G; de Los Ángeles Sevilla, M; El Bakkali, A; Escobar, B; González-Loyola, A; Jiménez-Borreguero, LJ; Malumbres, M; Martínez-Martínez, S; Méndez-Barbero, N; Montero, MJ; Mulero, F; Oller, J; Redondo, JM; Takaki, T; Wachowicz, P | 1 |
| Berliner, JA; Cai, L; Graham, MJ; Kim, S; Lee, RG; Lee, S; Lusis, AJ; Rateri, DL; Temel, RE; Yang, L | 1 |
| Tellides, G | 1 |
| Schiffrin, EL | 1 |
| Allen, TJ; Bach, LA; Biros, E; Chai, Z; Chow, B; Cooper, ME; Dai, A; Du, XJ; Golledge, J; Huynh, P; Kiriazis, H; Li, J; Nataatmadja, M; Tu, Y; Walker, P; West, M; Wilkinson-Berka, JL; Wu, T | 1 |
| Abe, T; Lee Fujimoto, K; Mutsuga, M; Narita, Y; Oshima, H; Tokuda, Y; Uchida, W; Usui, A; Yamawaki-Ogata, A | 1 |
| Ascaso, JF; Collado, A; Domingo, E; Escudero, P; Marques, P; Martinez-Hervás, S; Piqueras, L; Real, JT; Rius, C; Sanz, MJ | 1 |
| Chuma, M; Fujino, H; Fukushima, K; Horinouchi, Y; Ikeda, Y; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kohara, Y; Sairyo, E; Sakurada, T; Takechi, K; Tamaki, T; Tsuchiya, K; Yoshizumi, M; Zamami, Y | 1 |
| Bennett, MR; Bruneval, P; Chappell, J; Clément, M; Finigan, A; Harrison, J; Jørgensen, HF; Lareyre, F; Mallat, Z; Raffort, J; Taleb, S; Taylor, AL; Vandestienne, M | 1 |
| Andersen, ND; Cavanaugh, NB; Dyle, MC; Gensicke, NM; Huang, T; Qian, L; Turek, JW | 1 |
| Huang, J; Ikeda, Y; Inagami, T; Le, VP; Lin, Y; Papke, CL; Patel, M; Wagenseil, JE; Yamashiro, Y; Yanagisawa, H | 1 |
| Brasier, AR; Guo, DC; Ijaz, T; Ju, X; Lee, C; Lejeune, W; Milewicz, DM; Ray, S; Recinos, A; Sun, H; Tilton, RG | 1 |
| Choong, C; Huang, CL; Loo, JS; Luo, B; Tan, CK; Tan, EH; Tan, NS | 1 |
| Fu, XM; Narita, Y; Oshima, H; Ueda, Y; Usui, A; Yamawaki-Ogata, A | 1 |
| Bleeker, N; de Vries, CJ; de Waard, V; Girigorie, AF; Hamers, AA; Hibender, S; Hoogenboezem, M; Marinkovic, G; Stap, J; van Broekhoven, A; van Buul, JD | 1 |
| Babelova, A; Brandes, RP; Mieth, A; Revermann, M; Schermuly, RT; Weigert, A | 1 |
| Balakrishnan, A; Cassis, LA; Charnigo, R; Chen, X; Daugherty, A; Howatt, DA; Moorleghen, JJ; Morris, AJ; Rateri, DL | 1 |
| Daugherty, A; Davis, F; Rateri, DL | 1 |
| ap Rhys, CM; Bedja, D; Calderon, JF; Chen, Y; Cooke, SK; Dietz, HC; Gallo, EM; Gerber, EE; Habashi, JP; Huso, DL; Judge, DP; Kent, KC; Lindsay, ME; Loch, DC; Myers, L; Norris, RA; Parker, SJ; Rouf, R; Sauls, K; van Erp, C | 1 |
| Aoki, H; Aonuma, K; Furusho, A; Hamano, K; Hirakata, S; Hiroe, M; Ikeda, Y; Imaizumi, T; Imanaka-Yoshida, K; Ito, S; Kimura, T; Matsuzaki, M; Miyamoto, T; Nishida, N; Shiraishi, K; Ueno, T; Yoshida, T; Yoshimura, K | 1 |
| Bendall, JK; Channon, KM; Choudhury, RP; Crabtree, MJ; Douglas, G; Fan, LM; Hale, AB; Li, JM; Mai, A; McAteer, MA; McNeill, E; Schneider, JE | 1 |
| Chen, J; Deng, Y; Guo, D; Jiang, B; Li, D; Liu, X; Ma, H; Shen, X; Teng, F; Wu, W; Xu, F; Xu, J; Yang, M; Zhang, G; Zhang, L; Zhang, T; Zhang, Z | 1 |
| Balakrishnan, A; Cassis, LA; Charnigo, R; Daugherty, A; Davis, FM; Howatt, DA; Moorleghen, JJ; O'Connor, WN; Rateri, DL | 1 |
| Fischer, JW; Müeller, J; Tang, T; Tannock, LR; Thompson, JC; Williams, KJ; Wilson, PG; Yoder, MH | 1 |
| Balakrishnan, A; Cassis, LA; Daugherty, A; Davis, FM; Fornwalt, BK; Haggerty, CM; Howatt, DA; Muratoglu, SC; Rateri, DL; Strickland, DK | 1 |
| Chen, C; Harris, D; Li, S; Liang, Y; Patel, O; Qin, Z | 1 |
| Chen, M; Huo, Y; Qi, J; Sun, J; Yang, P; Yi, B; Zhang, J | 1 |
| Fraga-Silva, RA; Londono, FJ; Segers, P; Stergiopulos, N; Swillens, A; Trachet, B | 1 |
| Akiki, R; Bachschmid, M; Cohen, RA; Fry, JL; Gao, YZ; Morgan, KG; Seta, F; Shiraishi, Y; Turcotte, R; Yu, X; Zhang, Y | 1 |
| Gao, Y; Kong, W; Li, G; Wu, W; Yu, C; Zheng, J; Zhong, F | 1 |
| Bakker, EN; Palao, T; Rippe, C; Swärd, K; van Veen, H; VanBavel, E | 1 |
| Azares, AR; Coselli, JS; LeMaire, SA; Ren, P; Shen, YH; Zhang, L; Zhang, S; Zou, S | 1 |
| Anzai, J; Sano, M | 1 |
| Berceli, SA; DeSart, K; Fu, C; Jiang, Z; Oh, SP; Schmit, BM; Yang, P | 1 |
| de Waard, V; Wanga, S | 1 |
| Hu, X; Hu, Z; Huang, J; Li, B; Ren, Z; Wang, Z; Zhang, M; Zhou, Z | 1 |
| Towler, DA | 1 |
| Abe, J; Berk, BC; Cui, Z; Illig, KA; Matoba, T; Mohan, A; Nigro, P; O'Dell, MR; Satoh, K; Shi, X; Yan, C | 1 |
| Bader, M; Fonseca, RG; Merino, VF; Mori, MA; Pesquero, JB; Sales, VM; Saul, V; Tenner, K; Todiras, M | 1 |
| Brasier, AR; Guo, DC; Ju, X; Lee, C; Lejeune, W; Milewicz, D; Recinos, A; Spratt, H; Sun, H; Tieu, BC; Tilton, RG | 1 |
| Cassis, LA; Charo, IF; Daugherty, A; Howatt, DA; Owens, AP; Rateri, DL | 1 |
| Banno, F; Inoue, N; Kamide, K; Kawano, Y; Matsumoto, S; Miyata, T; Mochizuki, N | 1 |
| Lin, F; Yang, X | 1 |
| Balakrishnan, A; Cassis, LA; Charnigo, R; Daugherty, A; Howatt, DA; Moorleghen, JJ; Owens, AP; Poduri, A; Rateri, DL; Subramanian, V | 1 |
| Brandes, RP; Fischer, AS; Geisslinger, G; Maier, TJ; Mieth, A; Paulke, A; Pellowska, M; Popescu, L; Revermann, M; Schermuly, RT; Schubert-Zsilavecz, M; Steinhilber, D; Steri, R; Wurglics, M | 1 |
| Aziz, H; Bedja, D; Chen, Y; Dietz, HC; Doyle, JJ; Habashi, JP; Holm, TM; Judge, DP; Modiri, AN; Schoenhoff, F | 1 |
| Dietz, HC; Lindsay, ME | 1 |
| Courtman, DW; Rampersad, SN; Stewart, DJ; Suen, RS | 1 |
| Bouhuizen, AM; Danser, AH; de Waard, MC; Duncker, DJ; Essers, J; Lankhorst, S; Moltzer, E; Ramnath, NW; Rouwet, EV; Swagemakers, SM; te Riet, L; van der Spek, PJ; van Esch, JH; van Heijningen, PM; van Veghel, R; Vermeij, M | 1 |
| Boon, RA; Brandes, RP; Dimmeler, S; Essers, J; Fischer, A; Hergenreider, E; Heydt, S; Horrevoets, AJ; Pilato, M; Rosenthal, N; Sciacca, S; Seeger, T; van Heijningen, P; Vinciguerra, M; Zeiher, AM | 1 |
| Hashizume, R; Narita, Y; Ueda, Y; Wagner, WR; Yamawaki-Ogata, A | 1 |
| Bruemmer, D; Daugherty, A; Lu, H; Rateri, DL | 1 |
| Collins, MJ; Holzapfel, GA; Humphrey, JD; Niklason, LE; Pierce, DM; Schriefl, AJ | 1 |
| Cockerill, GW; Howe, F; Pirianov, G; Torsney, E | 1 |
| Bartlett, CS; Boyd, KL; Breyer, RM; Harris, RC; Zent, R | 1 |
| Balakrishnan, A; Cassis, LA; Daugherty, A; Howatt, DA; Moorleghen, JJ; Owens, AP; Poduri, A | 1 |
| Adachi, T; Aikawa, N; Hori, S; Itoh, H; Kurihara, T; Okada, Y; Shimizu, H; Shimizu-Hirota, R; Shimoda, M; Weiss, SJ | 1 |
| Cassis, LA; Chen, X; Daugherty, A; Lu, H; Rateri, DL | 1 |
| Fukumoto, H; Jin, D; Miyazaki, M; Nishimoto, M; Nishimoto, Y; Sakaguchi, M; Sasaki, S; Sawada, Y; Takai, S; Tsunemi, K; Yamada, M; Yuda, A | 1 |
| Fukumoto, H; Hasegawa, S; Miyazaki, M; Nishimoto, M; Sasaki, S; Sawada, Y; Takai, S; Tsunemi, K; Yuda, A | 1 |
| da Cunha, V; Deng, G; Ho, JJ; Martin-McNulty, B; Rutledge, JC; Sullivan, ME; Tham, DM; Vergona, R; Wang, YX; Wilson, DW | 1 |
| Ballard, N; Eagleton, MJ; Lynch, E; Srivastava, SD; Stanley, JC; Upchurch, GR | 1 |
| Jin, D; Miyazaki, M; Muramatsu, M; Takai, S | 1 |
| Harris, S; Naina, HV | 1 |
| Deffert, C; Gavazzi, G; Herrmann, FR; Krause, KH; Schäppi, M; Trocme, C | 1 |
| Grindlinger, GA; Hechtman, HB; Mannick, JA; Vegas, AM; Williams, GH | 1 |
| Higa, T; Kaseda, N; Kida, O; Kodama, K; Morotomi, Y; Tanaka, K; Wakisaka, O | 1 |
| Fukamizu, A; Kimoto, K; Murakami, K; Nishijo, N; Sugiyama, F; Suzuki, S; Taniguchi, K; Yagami, K | 1 |
| Arakawa, K; Ideishi, M; Ihara, M; Kikuchi, M; Kinoshita, A; Sasaguri, M; Suzumiya, J; Urata, H | 1 |
| Asada, K; Fukumoto, H; Hasegawa, S; Kondo, K; Miyazaki, M; Nishimoto, M; Nishimoto, Y; Sasaki, S; Sawada, Y; Takai, S; Tsunemi, K; Yuda, A | 1 |
| Becker, CE; Benowitz, NL | 1 |
| Boucher, R; Genest, J; Kuchel, O; Nowaczynski, W | 1 |
8 review(s) available for angiotensin ii and Aneurysm, Aortic
| Article | Year |
|---|---|
Contribution of ADAM17 and related ADAMs in cardiovascular diseases.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Animals; Aortic Aneurysm; Cardiovascular Diseases; Cytokines; Humans; Hypertension; Signal Transduction | 2021 |
Hypertension in 2017: Novel mechanisms of hypertension and vascular dysfunction.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Blood Pressure; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Immediate-Early Proteins; Intra-Abdominal Fat; Lymphocytes; Protein Serine-Threonine Kinases; Signal Transduction; Sodium Chloride; Solute Carrier Family 12, Member 2 | 2018 |
The molecular mechanisms contributing to the pathophysiology of systemic inflammatory response after acute aortic dissection.
Topics: Acute Disease; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Chemokines; Gene Expression; Humans; Immune System Diseases; Interleukin-6; Interleukin-8; Leukocyte Disorders; Mice; Molecular Targeted Therapy; Neutrophils; Receptors, Interleukin-8B; Systemic Inflammatory Response Syndrome | 2016 |
TGF-β signaling in aortic aneurysm: another round of controversy.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Disease Models, Animal; Humans; Signal Transduction; Smad Proteins; Transforming Growth Factor beta | 2010 |
Lessons on the pathogenesis of aneurysm from heritable conditions.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Disease Models, Animal; Elastin; Humans; Muscle, Smooth, Vascular; Transforming Growth Factor beta | 2011 |
Relevance of angiotensin II-induced aortic pathologies in mice to human aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Disease Models, Animal; Humans; Mice; Renin-Angiotensin System; Species Specificity | 2011 |
Conundrum of angiotensin II and TGF-β interactions in aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Humans; Transforming Growth Factor beta | 2013 |
Pathological roles of angiotensin II produced by mast cell chymase and the effects of chymase inhibition in animal models.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Aortic Aneurysm; Chymases; Fibrosis; Heart Diseases; Humans; Hypertension; Mast Cells; Myocardial Infarction; Neovascularization, Pathologic; Serine Proteinase Inhibitors | 2006 |
84 other study(ies) available for angiotensin ii and Aneurysm, Aortic
| Article | Year |
|---|---|
Rosmarinic Acid Suppresses Abdominal Aortic Aneurysm Progression in Apolipoprotein E-deficient Mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Cinnamates; Depsides; Disease Models, Animal; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Rosmarinic Acid | 2022 |
CCN2 (Cellular Communication Network Factor 2) Deletion Alters Vascular Integrity and Function Predisposing to Aneurysm Formation.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Connective Tissue Growth Factor; Disease Models, Animal; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction; Up-Regulation | 2022 |
Edaravone Attenuated Angiotensin II-Induced Atherosclerosis and Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Atherosclerosis; Edaravone; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, LDL; RNA, Messenger | 2022 |
Moxifloxacin induces aortic aneurysm and dissection by increasing osteopontin in mice.
Topics: Angiotensin II; Animals; Anti-Bacterial Agents; Aortic Aneurysm; Aortic Dissection; Disease Models, Animal; Elastin; Eosine Yellowish-(YS); Hematoxylin; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Moxifloxacin; Muscle Proteins; Myocytes, Smooth Muscle; Osteopontin; Rubber; Water | 2022 |
NCOR1 maintains the homeostasis of vascular smooth muscle cells and protects against aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Cells, Cultured; Homeostasis; Mice; Mice, Knockout; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Nuclear Receptor Co-Repressor 1; Phenotype | 2023 |
Phospholipase Cε insufficiency causes ascending aortic aneurysm and dissection.
Topics: Aneurysm, Ascending Aorta; Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic Valve Insufficiency; Death, Sudden; Humans; Hypertension; Mice; Mice, Inbred C57BL | 2022 |
Loss of myeloid Tsc2 predisposes to angiotensin II-induced aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Metalloproteases; Mice; Receptors, G-Protein-Coupled; Tuberous Sclerosis | 2022 |
Distinct Mechanisms of β-Arrestin-Biased Agonist and Blocker of AT1R in Preventing Aortic Aneurysm and Associated Mortality.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; beta-Arrestins; Female; Male; Mice; Mice, Knockout; Receptor, Angiotensin, Type 1 | 2023 |
Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Folic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Nifedipine | 2022 |
Nicotinamide Mononucleotide Alleviates Angiotensin II-Induced Human Aortic Smooth Muscle Cell Senescence in a Microphysiological Model.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Humans; Myocytes, Smooth Muscle; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase | 2023 |
Administration of anti-inflammatory M2 macrophages suppresses progression of angiotensin II-induced aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm; Disease Models, Animal; Macrophages; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha | 2023 |
Mesenchymal stem cell-derived conditioned medium attenuate angiotensin II-induced aortic aneurysm growth by modulating macrophage polarization.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Bone Marrow Cells; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Gene Expression; Interleukin-10; Interleukin-6; Macrophage Activation; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mesenchymal Stem Cells; Mice, Knockout | 2019 |
Inactivation of cysteine 674 in the SERCA2 accelerates experimental aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Calcineurin; Cholesterol; Cysteine; Down-Regulation; Humans; Mice, Inbred C57BL; Myocytes, Smooth Muscle; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Osteopontin; Oxidation-Reduction; Phenotype; Receptors, LDL; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Trans-Activators; Triglycerides; Up-Regulation | 2020 |
Smooth muscle NADPH oxidase 4 promotes angiotensin II-induced aortic aneurysm and atherosclerosis by regulating osteopontin.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Atherosclerosis; Humans; Mice; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; NADPH Oxidase 4; Osteopontin | 2020 |
Deficiency in Aim2 affects viability and calcification of vascular smooth muscle cells from murine aortas and angiotensin-II induced aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Calcinosis; Cell Proliferation; Cell Survival; Cellular Senescence; Disease Models, Animal; Disease Susceptibility; DNA-Binding Proteins; Inflammasomes; Mice; Mice, Knockout; Myocytes, Smooth Muscle | 2020 |
Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Atherosclerosis; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Mice; Protein-Lysine 6-Oxidase; Quercetin | 2020 |
A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs).
Topics: Aminopropionitrile; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Disease Models, Animal; Estradiol; Estrogens; Female; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Myeloid Cells | 2020 |
Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Aortic Rupture; Aortography; Computed Tomography Angiography; Contrast Media; Diet, High-Fat; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Early Diagnosis; Male; Mice, Inbred C57BL; Nanoparticles; Predictive Value of Tests; Time Factors; Triiodobenzoic Acids; X-Ray Microtomography | 2021 |
Adventitial recruitment of Lyve-1- macrophages drives aortic aneurysm in an angiotensin-2-based murine model.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Inflammation; Inflammation Mediators; Macrophages; Membrane Transport Proteins; Mice; Signal Transduction | 2021 |
Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Blood Pressure; Cell Cycle Proteins; Cell Proliferation; Fluorescent Antibody Technique; Gene Knockdown Techniques; Haploinsufficiency; Homeostasis; Hypotension; Immunoblotting; Mice; Microscopy, Electron, Transmission; Mitosis; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Vascular Stiffness | 2017 |
Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Atherosclerosis; Disease Models, Animal; Heparin-binding EGF-like Growth Factor; Hyperlipidemias; Liver; Male; Mice; Receptors, LDL | 2017 |
Further Evidence Supporting a Protective Role of Transforming Growth Factor-β (TGFβ) in Aortic Aneurysm and Dissection.
Topics: Angiotensin II; Aorta, Abdominal; Aortic Aneurysm; Humans; Transforming Growth Factor beta; Transforming Growth Factors | 2017 |
Diabetes Reduces Severity of Aortic Aneurysms Depending on the Presence of Cell Division Autoantigen 1 (CDA1).
Topics: Adult; Aged; Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Aortic Rupture; Autoantigens; Collagen; Diabetes Mellitus, Experimental; Female; Gene Expression Regulation; Humans; Macrophages; Male; Matrix Metalloproteinase 12; Mice; Mice, Knockout; Mice, Knockout, ApoE; Middle Aged; Severity of Illness Index; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta; Vasoconstrictor Agents | 2018 |
The oral administration of clarithromycin prevents the progression and rupture of aortic aneurysm.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Cells, Cultured; Clarithromycin; Disease Models, Animal; Elastin; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Macrophages; Male; Matrix Metalloproteinases, Secreted; Mice, Inbred C57BL; Mice, Knockout, ApoE; NF-kappa B; Phosphorylation; Vascular Remodeling | 2018 |
Functional role of endothelial CXCL16/CXCR6-platelet-leucocyte axis in angiotensin II-associated metabolic disorders.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Aneurysm; Blood Platelets; Case-Control Studies; Cell Adhesion; Cells, Cultured; Chemokine CXCL16; Coculture Techniques; Disease Models, Animal; Endothelial Cells; Female; Humans; Leukocytes; Male; Metabolic Syndrome; Mice, Inbred C57BL; Mice, Knockout, ApoE; Middle Aged; Platelet Activation; Receptors, CXCR6; Signal Transduction | 2018 |
Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation.
Topics: Aminopropionitrile; Angiotensin II; Animals; Antigens, Differentiation; Antioxidants; Aortic Aneurysm; Chemokine CCL2; Cyclophilins; Disease Models, Animal; Elastin; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; Matrix Metalloproteinase 2; Mice; Nifedipine; Nitroso Compounds; Oxidative Stress; Photolysis; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2018 |
Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms.
Topics: Adult; Aged; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Autophagy; Autophagy-Related Protein 5; Cell Lineage; Cell Plasticity; Cells, Cultured; Disease Models, Animal; Endoribonucleases; Female; Humans; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout, ApoE; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Protein Serine-Threonine Kinases; Signal Transduction | 2019 |
Accelerated Marfan syndrome model recapitulates established signaling pathways.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Cardiomyopathies; Dilatation, Pathologic; Disease Models, Animal; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Fibrillin-1; Genetic Predisposition to Disease; Heterozygote; Marfan Syndrome; Mice, Mutant Strains; Mutation; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenotype; Phosphorylation; Signal Transduction; Smad2 Protein; Time Factors; Transforming Growth Factor beta | 2020 |
Angiotensin-converting enzyme-induced activation of local angiotensin signaling is required for ascending aortic aneurysms in fibulin-4-deficient mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Biomarkers; Biomechanical Phenomena; Blood Pressure; Captopril; Cell Differentiation; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Deletion; Losartan; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptidyl-Dipeptidase A; Phenotype; Phosphorylation; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Time Factors; Up-Regulation | 2013 |
Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin II via the T-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice.
Topics: Angiotensin II; Animals; Antibodies, Neutralizing; Aorta; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation Mediators; Interleukin-17; Interleukin-6; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Th17 Cells; Tissue Culture Techniques | 2013 |
SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortitis; Male; Mice; Mice, Knockout; Nitric Oxide Synthase Type II; Phenotype; Smad3 Protein | 2013 |
Intravenous administration of mesenchymal stem cells prevents angiotensin II-induced aortic aneurysm formation in apolipoprotein E-deficient mouse.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Bone Marrow Cells; Cytokines; Disease Progression; Elastin; Femur; Inflammation; Injections, Intravenous; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Knockout | 2013 |
Immunosuppressive drug azathioprine reduces aneurysm progression through inhibition of Rac1 and c-Jun-terminal-N-kinase in endothelial cells.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aortic Aneurysm; Aortic Rupture; Apolipoproteins E; Azathioprine; Cell Line, Tumor; Coculture Techniques; Disease Models, Animal; Disease Progression; Endothelial Cells; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Immunosuppressive Agents; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Mercaptopurine; Mice; Mice, Knockout; Monocytes; Neuropeptides; Phosphorylation; Protein Kinase Inhibitors; rac1 GTP-Binding Protein; Signal Transduction | 2013 |
L-type calcium channel inhibitor diltiazem prevents aneurysm formation by blood pressure-independent anti-inflammatory effects.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm; Apolipoproteins E; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Diltiazem; Disease Models, Animal; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Transcription Factor AP-1 | 2013 |
Amlodipine reduces AngII-induced aortic aneurysms and atherosclerosis in hypercholesterolemic mice.
Topics: Amlodipine; Angiotensin II; Animals; Aortic Aneurysm; Atherosclerosis; Hyperlipoproteinemia Type II; Male; Mice; Mice, Knockout; Receptors, LDL | 2013 |
Aortic aneurysms in Loeys-Dietz syndrome - a tale of two pathways?
Topics: Angiotensin II; Animals; Aortic Aneurysm; Female; Humans; Loeys-Dietz Syndrome; Transforming Growth Factor beta | 2014 |
Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Aortic Aneurysm; Cells, Cultured; Disease Progression; Female; Haploinsufficiency; Humans; Loeys-Dietz Syndrome; Losartan; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Myocytes, Smooth Muscle; Phenotype; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta | 2014 |
Tenascin C protects aorta from acute dissection in mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Calcium Chloride; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Hemodynamics; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Signal Transduction; Tenascin; Transforming Growth Factor beta | 2014 |
Endothelial cell-specific reactive oxygen species production increases susceptibility to aortic dissection.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Cyclophilins; Disease Models, Animal; Disease Susceptibility; Endothelium, Vascular; Male; Matrix Metalloproteinases; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Reactive Oxygen Species; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2014 |
Salvianolic acid A, a matrix metalloproteinase-9 inhibitor of Salvia miltiorrhiza, attenuates aortic aneurysm formation in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Lactates; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Knockout; Salvia miltiorrhiza | 2014 |
Angiotensin II induces region-specific medial disruption during evolution of ascending aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Tunica Media | 2014 |
Biglycan deficiency: increased aortic aneurysm formation and lack of atheroprotection.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Atherosclerosis; Biglycan; Diet, Western; Female; Genotype; Heparan Sulfate Proteoglycans; Male; Mice, Inbred C57BL; Rupture; Survival Analysis | 2014 |
Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms.
Topics: Aneurysm; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Arterial Pressure; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Elastin; Gene Deletion; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Male; Matrix Metalloproteinase 2; Mesenteric Artery, Superior; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Norepinephrine; Receptors, LDL; RNA, Messenger; Tumor Suppressor Proteins; Urokinase-Type Plasminogen Activator | 2015 |
Bone marrow from blotchy mice is dispensable to regulate blood copper and aortic pathologies but required for inflammatory mediator production in LDLR-deficient mice during chronic angiotensin II infusion.
Topics: Adenosine Triphosphatases; Angiotensin II; Animals; Aortic Aneurysm; Aortic Rupture; Biomarkers; Bone Marrow; Bone Marrow Transplantation; Cardiovascular Agents; Cation Transport Proteins; Copper; Copper-Transporting ATPases; Cytokines; Disease Models, Animal; Enzymes; Female; Lipids; Male; Mice; Mice, Inbred Strains; Receptors, LDL | 2015 |
Heat shock protein 90 inhibition by 17-DMAG attenuates abdominal aortic aneurysm formation in mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Apolipoproteins E; Benzoquinones; Cells, Cultured; Chemokine CCL2; HSP90 Heat-Shock Proteins; I-kappa B Kinase; Lactams, Macrocyclic; Male; MAP Kinase Signaling System; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Oxidative Stress | 2015 |
Performance comparison of ultrasound-based methods to assess aortic diameter and stiffness in normal and aneurysmal mice.
Topics: Angiotensin II; Animals; Antibodies; Aorta; Aortic Aneurysm; Male; Mice; Mice, Knockout; Transforming Growth Factor beta; Ultrasonography; Vascular Stiffness | 2015 |
Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Cells, Cultured; Cyclic N-Oxides; Disease Models, Animal; Elastic Tissue; Elastin; Free Radical Scavengers; Hypertension; Matrix Metalloproteinases; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Sirtuin 1; Spin Labels; Time Factors | 2015 |
A disintegrin and metalloproteinase with thrombospondin motif 1 (ADAMTS1) expression increases in acute aortic dissection.
Topics: ADAM Proteins; ADAMTS1 Protein; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Case-Control Studies; Disease Models, Animal; Female; Humans; Immunohistochemistry; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; Neutrophils; RNA, Messenger; Up-Regulation; Versicans | 2016 |
Thrombospondin-4 knockout in hypertension protects small-artery endothelial function but induces aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Cardiomegaly; Collagen; Dilatation, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Genetic Predisposition to Disease; Hypertension; Mesenteric Arteries; Mice, Knockout; Microscopy, Electron; Phenotype; Thrombospondins; Vascular Resistance; Vasodilation; Vasodilator Agents | 2016 |
AKT2 Promotes Bone Marrow Cell-Mediated Aortic Protection in Mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Apoptosis; Bone Marrow Cells; Cell Movement; Cells, Cultured; Coculture Techniques; Fibroblasts; Genes, Reporter; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pericytes; Proto-Oncogene Proteins c-akt; Radiation Chimera; Signal Transduction; Stem Cells | 2016 |
Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Gene Deletion; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 3; Myocytes, Smooth Muscle; Peptidyl-Dipeptidase A; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Angiotensin; Receptors, Transforming Growth Factor beta | 2016 |
Bile-ated Cell Death Decreases Aortic Aneurysm Formation.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Apolipoproteins; Bile; Cell Death; Endoplasmic Reticulum Stress; Mice; Taurochenodeoxycholic Acid | 2017 |
P38 MAPK Signaling Pathway Mediates Angiotensin II-Induced miR143/145 Gene Cluster Downregulation during Aortic Dissection Formation.
Topics: Actins; Adult; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Case-Control Studies; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; Male; Mice, Inbred C57BL; MicroRNAs; Middle Aged; Multigene Family; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Time Factors | 2017 |
"Osteotropic" Wnt/LRP Signals: High-Wire Artists in a Balancing Act Regulating Aortic Structure and Function.
Topics: Angiotensin II; Aortic Aneurysm; Atherosclerosis; Humans; Wnt Proteins; Wnt Signaling Pathway | 2017 |
Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Cyclophilin A; Mice; Mice, Knockout; Oxidative Stress; Reactive Oxygen Species | 2009 |
Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Apolipoproteins E; Atherosclerosis; Biomarkers; Cholesterol; Diet; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Bradykinin B1; RNA, Messenger | 2009 |
An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Base Sequence; Chemokine CCL2; Coculture Techniques; Connective Tissue; Disease Models, Animal; DNA Primers; Humans; Inflammation; Interleukin-6; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, CCR2; Signal Transduction | 2009 |
Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-/- mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Blood Pressure; Body Weight; Cholesterol; Disease Models, Animal; Hypercholesterolemia; Lipids; Male; Mice; Mice, Knockout; Receptors, CCR2; Vasodilation | 2010 |
Impact of RGS2 deficiency on the therapeutic effect of telmisartan in angiotensin II-induced aortic aneurysm.
Topics: Alleles; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Aortic Aneurysm; Benzimidazoles; Benzoates; Blood Pressure; Genotype; Male; Mice; Mice, Knockout; Neovascularization, Physiologic; RGS Proteins; Superoxides; Telmisartan | 2010 |
Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Cell Communication; Disease Models, Animal; Endothelial Cells; Macrophages; Mice; Mice, Knockout; Mice, Mutant Strains; Mutation; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1; Receptors, LDL | 2011 |
A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Arachidonate 5-Lipoxygenase; Cardiotonic Agents; Cardiovascular System; Cell Line; Cyclooxygenase Inhibitors; Disease Models, Animal; Epoxide Hydrolases; Injections, Subcutaneous; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-E Synthases; Pyrimidines | 2011 |
Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Disease Models, Animal; Disease Progression; Enalapril; Losartan; MAP Kinase Signaling System; Marfan Syndrome; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, Angiotensin, Type 2; Signal Transduction; Transforming Growth Factor beta | 2011 |
Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Aortic Aneurysm; Apolipoproteins E; Atherosclerosis; Biomechanical Phenomena; Bosentan; Cardiovascular Agents; Cell Adhesion; Collagen; Down-Regulation; Endothelin-1; Integrin beta1; Interferon-gamma; Mice; Mice, Knockout; Stress, Physiological; Sulfonamides; Vasoconstrictor Agents | 2011 |
Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Aorta, Thoracic; Aortic Aneurysm; Extracellular Matrix Proteins; Female; Humans; Immunohistochemistry; In Vitro Techniques; Losartan; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Phenylephrine; Pregnancy; Receptor, Angiotensin, Type 1; Smad2 Protein; Transcriptome; Transforming Growth Factor beta; Vasoconstriction; Vasoconstrictor Agents | 2011 |
MicroRNA-29 in aortic dilation: implications for aneurysm formation.
Topics: Aging; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Biopsy; Dilatation, Pathologic; Disease Models, Animal; Extracellular Matrix Proteins; Gene Expression Profiling; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Mutation; Oligoribonucleotides, Antisense | 2011 |
Mesenchymal stem cells attenuate angiotensin II-induced aortic aneurysm growth in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Apolipoproteins E; Cell Culture Techniques; Coculture Techniques; Disease Models, Animal; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Vasoconstrictor Agents | 2011 |
Remodeling of intramural thrombus and collagen in an Ang-II infusion ApoE-/- model of dissecting aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Apolipoproteins E; Collagen; Disease Models, Animal; Humans; Infusions, Intra-Arterial; Male; Mice; Mice, Knockout; Thrombosis; Vasodilator Agents | 2012 |
Rosiglitazone negatively regulates c-Jun N-terminal kinase and toll-like receptor 4 proinflammatory signalling during initiation of experimental aortic aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Rupture; Down-Regulation; JNK Mitogen-Activated Protein Kinases; Mice; Phosphorylation; Rosiglitazone; Signal Transduction; Thiazolidinediones; Toll-Like Receptor 4 | 2012 |
EP1 disruption attenuates end-organ damage in a mouse model of hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aortic Aneurysm; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Female; Humans; Hydralazine; Hypertension; Kaplan-Meier Estimate; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Receptors, Prostaglandin E, EP1 Subtype | 2012 |
Regional variation in aortic AT1b receptor mRNA abundance is associated with contractility but unrelated to atherosclerosis and aortic aneurysms.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Arterial Pressure; Atherosclerosis; Gene Expression Regulation; Male; Mice; Mice, Knockout; Muscle Contraction; Receptor, Angiotensin, Type 1; RNA, Messenger; Transcription, Genetic | 2012 |
Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection.
Topics: Acute Disease; Aged; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Disease Models, Animal; Female; Humans; Male; Matrix Metalloproteinase 9; Mice; Middle Aged; Neutrophil Infiltration; Neutrophils | 2012 |
Increased local angiotensin II formation in aneurysmal aorta.
Topics: Aged; Aged, 80 and over; Angiotensin II; Aorta; Aortic Aneurysm; Chymases; Female; Humans; Immunohistochemistry; In Vitro Techniques; Male; Middle Aged; Peptidyl-Dipeptidase A; Serine Endopeptidases | 2002 |
Possible roles of angiotensin II-forming enzymes, angiotensin converting enzyme and chymase-like enzyme, in the human aneurysmal aorta.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Aorta; Aortic Aneurysm; Chymases; Humans; In Vitro Techniques; Male; Middle Aged; Peptidyl-Dipeptidase A; Reference Values; Serine Endopeptidases; Tunica Intima; Tunica Media | 2002 |
Enalapril attenuates angiotensin II-induced atherosclerosis and vascular inflammation.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Arteriosclerosis; Cell Adhesion Molecules; Chemokines; Enalapril; Endothelium; Gene Expression; Male; Mice; Mice, Knockout; PPAR alpha; PPAR gamma; RNA, Messenger; Up-Regulation; Vasculitis | 2005 |
Early increased MT1-MMP expression and late MMP-2 and MMP-9 activity during Angiotensin II induced aneurysm formation.
Topics: Analysis of Variance; Angiotensin II; Animals; Aortic Aneurysm; Apolipoproteins E; Gene Expression Regulation, Enzymologic; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2006 |
ACE inhibitors and aortic rupture.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Aneurysm; Atherosclerosis; Humans; Losartan; Mice | 2006 |
NOX1 deficiency protects from aortic dissection in response to angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Blood Pressure; Disease Susceptibility; Gene Expression Regulation; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 1; NADPH Oxidases; Norepinephrine; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Vasoconstrictor Agents | 2007 |
Independence of renin production and hypertension in abdominal aortic aneurysmectomy.
Topics: Aged; Angiotensin II; Aorta, Abdominal; Aortic Aneurysm; Blood Pressure; Constriction; Female; Hemodynamics; Humans; Hypertension; Intraoperative Period; Male; Middle Aged; Postoperative Complications; Postoperative Period; Renin | 1981 |
[Renin-angiotensin system in a case of renovascula hypertension caused by acute dissecting aneurysm of the aorta (author's transl)].
Topics: Angiotensin II; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Female; Humans; Hypertension, Renal; Hypertension, Renovascular; Middle Aged; Renin | 1981 |
Salt-sensitive aortic aneurysm and rupture in hypertensive transgenic mice that overproduce angiotensin II.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Rupture; Drug Resistance; Female; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Sodium Chloride | 1998 |
Increased chymase-dependent angiotensin II formation in human atherosclerotic aorta.
Topics: Aged; Aged, 80 and over; Angiotensin II; Aorta; Aortic Aneurysm; Arteriosclerosis; Chymases; Female; Humans; Immunohistochemistry; Male; Middle Aged; Peptidyl-Dipeptidase A; Reference Values; Serine Endopeptidases | 1999 |
[Role of angiotensin II-forming pathway in ruptured aortic aneurysms].
Topics: Angiotensin II; Aortic Aneurysm; Aortic Rupture; Humans | 2001 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Animals; Aortic Aneurysm; Aortic Dissection; Brain Diseases; Cerebrovascular Disorders; Diazoxide; Dogs; Emergencies; Female; Heart Diseases; Humans; Hydralazine; Hypertension; Methyldopa; Nitroprusside; Pheochromocytoma; Pre-Eclampsia; Pregnancy; Reserpine; Trimethaphan | 1979 |
Renin in hypertension: how important as a risk factor?
Topics: Adult; Angiotensin II; Aortic Aneurysm; Aortic Rupture; Blood Pressure; Cerebrovascular Disorders; Creatinine; Follow-Up Studies; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Middle Aged; Myocardial Infarction; Posture; Potassium; Renal Artery Obstruction; Renin; Sodium; Urea | 1973 |