angiotensin ii has been researched along with Aging in 402 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 78 (19.40) | 18.7374 |
| 1990's | 95 (23.63) | 18.2507 |
| 2000's | 84 (20.90) | 29.6817 |
| 2010's | 118 (29.35) | 24.3611 |
| 2020's | 27 (6.72) | 2.80 |
| Authors | Studies |
|---|---|
| Alenina, N; Bader, M; Clahsen-van Groningen, MC; Danser, AHJ; Essers, J; Garrelds, IM; Qadri, F; Ridwan, Y; Roks, AJM; van der Linden, J; van der Pluijm, I; van Thiel, BS; Vermeij, M | 1 |
| Balatskaya, M; Balatskiy, A; Filatova, J; Kalinina, N; Ozhimalov, I; Popov, V; Savina, A; Tkachuk, V | 1 |
| De la Cuesta, F; Peiró, C; Romero, A; Sánchez-Ferrer, CF; Shamoon, L | 1 |
| Chrissobolis, S; D'Souza, MS; Guisinger, TC; Luu, AN; Seeley, SL; Waldschmidt, RA | 1 |
| Kehoe, PG; MacLachlan, R; Miners, JS | 1 |
| Chi, C; Fu, H; Fu, JT; Ji, QX; Li, DJ; Li, YH; Li, ZC; Liu, J; Shen, FM; Shen, QR; Sun, DY; Wang, P; Wang, XJ; Wu, WB; Zeng, FY; Zhang, GY; Zhang, JB; Zhang, PP; Zhou, CC | 1 |
| Liu, X; Qiu, L; Xia, H; Xu, C | 1 |
| Mogi, M; Nozato, S; Rakugi, H; Takeshita, H; Yamamoto, K | 1 |
| Chittimalli, K; Ericsson, AC; Jahan, J; Jarajapu, YPR; McAdams, ZL; Sakamuri, A | 1 |
| Li, Q; Prasad, T; Verma, A; Zhu, P | 1 |
| Aquino, V; Buford, TW; Carter, CS; Li, Q; Lobaton, G; Morgan, D; Raizada, M; Sumners, E; Verma, A | 1 |
| Bellini, C; Caulk, AW; Ferruzzi, J; Humphrey, JD; Murtada, SI; Spronck, B | 1 |
| Chen, HZ; Ding, YN; Hao, L; Liu, P; Lv, SJ; Pei, XY; Zhang, ZQ; Zhao, X | 1 |
| Mogi, M | 1 |
| Ayuzawa, N; Fujita, T; Hirohama, D; Kawakami-Mori, F; Kawarazaki, W; Marumo, T; Mizuno, R; Nishimoto, M; Oba, S; Ueda, K | 1 |
| Goronzy, JJ; Weyand, CM | 1 |
| Hada, Y; Nishiwaki, M; Okamoto, S; Onishi, Y; Otaka, N; Takemoto, R; Takeuchi, H; Uchida, HA; Wada, J | 1 |
| Cicalese, S; Eguchi, S; Elliott, KJ; Hashimoto, T; Kawai, T; Okuno, K | 1 |
| Busch, K; Engelhardt, S; Esfandyari, D; Fischer, M; Ishikawa-Ankerhold, H; Klapproth, K; Klösges, L; Kobayashi, Y; Liu, L; Massberg, S; Messerer, D; Molkentin, JD; Percin, G; Perdiguero, EG; Schleifer, C; Schneider, V; Schulz, C; Schwanenkamp, J; Stremmel, C; Thaler, R; Titova, A; Vagnozzi, RJ; Waskow, C; Weinberger, T | 1 |
| Juin, SK; Kulkarni, R; Majumder, S; Pushpakumar, S; Ren, L; Sen, U | 1 |
| Fujita, T; Kawarazaki, W | 1 |
| Cai, X; Huang, W; Jiang, D; Liang, Y; Liu, X; Teng, P; Wei, C; Zhang, H | 1 |
| Barsha, G; Denton, KM; Gaspari, TA; Hilliard Krause, LM; Mirabito Colafella, KM; Pinar, AA; Samuel, CS; Spizzo, I; Walton, SL; Widdop, RE | 1 |
| Pawlikowski, M; Winczyk, K | 1 |
| Chukwunyere, U; Sayıner, S; Sehirli, AO; Serakinci, N | 1 |
| Csiszar, A; Lindsey, ML; Tarantini, S; Ungvari, Z; Yabluchanskiy, A | 1 |
| Adachi, H; Berkowitz, DE; Biswas, D; Das, S; Dunkerly-Eyring, B; Flavell, RA; Henao-Mejia, J; Hori, D; Nomura, Y; Santhanam, L; Steenbergen, C; Steppan, J | 1 |
| Nishida, M; Nishimura, A; Numaga-Tomita, T; Shimoda, K; Sunggip, C; Tsuda, M | 1 |
| Bautista-Niño, PK; Brandt, RMC; Danser, AHJ; Dollé, MET; Durik, M; Essers, J; Hoeijmakers, JHJ; Leijten, FPJ; Reiling, E; Ridwan, Y; Roks, AJM; van der Pluijm, I; van Steeg, H; van Thiel, BS; Vermeij, WP; Wu, H | 1 |
| Chrissobolis, S; Cooper, MA; De Silva, TM; Diep, H; Dinh, QN; Drummond, GR; Kemp-Harper, BK; Kim, HA; Mansell, A; Robertson, AAB; Sobey, CG; Vinh, A | 1 |
| Smith, FG; Vinturache, AE | 1 |
| Costa-Besada, MA; Labandeira-Garcia, JL; Melendez-Ferro, M; Perez-Costas, E; Valenzuela, R; Villar-Cheda, B | 1 |
| Carai, P; Deckx, S; Diez, J; Dresselaers, T; Gonzalez, A; Heggermont, W; Heymans, S; Himmelreich, U; Lommen, W; Papageorgiou, AP; Rienks, M; van der Velden, J; van Leeuwen, R | 1 |
| Costa-Besada, MA; Garrido-Gil, P; Labandeira-Garcia, JL; Lanciego, JL; Parga, JA; Valenzuela, R; Villar-Cheda, B | 1 |
| Feng, P; Li, N; Liu, Z; Wang, G; Wang, W; Wang, X | 1 |
| He, T; Katusic, ZS; Pan, Y; Sun, R | 1 |
| Ballabh, P; Conley, SM; Csiszar, A; Fulop, GA; Kiss, T; Martinez-Lemus, LA; Ramirez-Perez, FI; Tarantini, S; Toth, P; Ungvari, Z; Valcarcel Ares, MN; Yabluchanskiy, A | 1 |
| Lei, D; Ruan, Y; Wei, C; Zhang, L; Zhang, Y; Zhou, Y | 1 |
| Purkayastha, B; Pushpakumar, S; Ren, L; Sen, U; Weber, GJ | 1 |
| Cooper, HA; Eguchi, S; Rizzo, V; Scalia, R | 1 |
| Akishita, M; Endo, T; Hashizume, T; Ito, K; Nanao-Hamai, M; Noda, Y; Ogawa, S; Son, BK; Taniguchi, S | 1 |
| Abbas, M; Amoura, L; Auger, C; Belcastro, E; Idris-Khodja, N; Kessler, L; Khemais-Benkhiat, S; Mayoux, E; Park, SH; Schini-Kerth, VB; Toti, F | 1 |
| Chen, N; He, R; Li, J; Mao, C; Rui, C; Shi, A; Tang, J; Tao, H; Tao, J; Wu, C; Wu, L; Xiao, J; Xu, Z; Yin, X; Zhang, P; Zheng, J; Zhu, Z | 1 |
| Jaffe, IZ; McCurley, A; McGraw, A; Pruthi, D | 1 |
| Hirose, M; Ishigami, A; Kobayashi, A; Kubota, I; Misaka, T; Miyata, M; Saitoh, S; Shishido, T; Suzuki, S; Takeishi, Y | 1 |
| Guo, ZY; Li, JH; Li, JJ; Liang, XY; Wu, CY; Xia, QQ; Yuan, Y; Zha, H | 1 |
| Amor, S; Carreño-Tarragona, G; Fernández, N; Figueras, JC; García-Villalón, AL; Granado, M; Monge, L | 1 |
| Csiszar, A; Deak, F; Gautam, T; Koller, A; Mitschelen, M; Sonntag, WE; Sosnowska, D; Tarantini, S; Toth, P; Tucsek, Z; Ungvari, Z | 1 |
| Arpino, JM; Chu, MW; Gros, R; Nong, Z; O'Neil, C; Pickering, JG; Vafaie, F; Watson, A; Wayne Holdsworth, D; Yin, H | 1 |
| Cseplo, P; Hamar, J; Ivic, I; Koller, A; Matics, R; Vamos, Z | 1 |
| Csiszar, A; Gautam, T; Koller, A; Schwartzman, ML; Sonntag, WE; Sosnowska, D; Toth, P; Tucsek, Z; Ungvari, Z | 1 |
| Llinas, MT; Loria, A; Reverte, V; Salazar, F; Salazar, FJ; Tapia, A | 1 |
| Jiang, L; Lakatta, EG; Monticone, RE; Wang, M | 1 |
| Fukuda, T; Kono, M; Kuroda, T; Matsui, T; Miyamoto, T; Tanaka, M | 1 |
| Bai, X; Chen, X; Jin, B; Li, X; Shan, H; Yu, K; Zhang, S; Zhao, X | 1 |
| Chandramouli, C; Curl, CL; Delbridge, LM; Mellor, KM; Pedrazzini, T; Wendt, IR | 1 |
| Barton, M; Fredette, NC; Meyer, MR; Prossnitz, ER | 1 |
| Iadecola, C; Marques-Lopes, J; Milner, TA; Pickel, VM; Van Kempen, T; Waters, EM | 1 |
| Gao, HM; Gao, YX; Kong, W; Li, G; Lu, JH; Yu, CA; Zheng, J | 1 |
| Bai, X; Guo, D; Li, W; Li, X; Shan, H; Zhao, X | 1 |
| Bao, Z; Du, Q; Fu, G; Ge, J; Hong, W; Hu, X; Li, H; Qiu, Z; Wang, M; Yao, J; Ye, Y; Zhang, W; Zhao, G | 1 |
| Carreón-Torres, E; Castrejón-Tellez, V; Del Valle-Mondragón, L; Díaz-Díaz, E; Guarner-Lans, V; Rubio-Ruíz, ME | 1 |
| Cui, J; Liu, H; Liu, L; Qiao, WL; Shi, Y; Yan, CD; Yang, WX | 1 |
| Lakatta, EG; Monticone, RE; Wang, M | 2 |
| Li, Q; Liu, X; Wei, J | 1 |
| Csiszar, A; Gautam, T; Koller, A; Mitschelen, M; Sonntag, WE; Sosnowska, D; Tarantini, S; Toth, P; Tucsek, Z; Ungvari, Z | 1 |
| Black, MJ; Blaschke, F; Cox, TC; Drenckhahn, JD; Fischer, R; Heinecke, K; Hennig, M; Heuser, A; Langner, P; Skole, F; Spallek, B; Strasen, J; Thierfelder, L; Yin, KV | 1 |
| Han, YL; Li, Y; Song, HX; Sun, MY; Tian, XX; Yan, CH; Zhang, J; Zhu, N | 1 |
| Carlström, M; Fredholm, BB; Gao, X; Harris, RA; Hezel, M; Jansson, L; Lai, EY; Liu, M; Peleli, M; Persson, AE; Sandberg, M; Yang, T; Zhang, XM; Zollbrecht, C | 1 |
| Richardson, RS; Wray, DW | 1 |
| de Cavanagh, EM; Ferder, L; Inserra, F | 2 |
| Cai, WL; Chao, M; Gao, M; Hui, LH; Lu, QH; Wang, J; Xu, DL; Zhang, GH; Zhang, MX; Zheng, J | 1 |
| Beiroa, D; Diaz-Ruiz, C; Labandeira-Garcia, JL; Rodriguez-Pallares, J; Rodriguez-Perez, AI | 1 |
| Brdar, M; Dear, AE; Gaspari, T; Hu, Y; Lee, HW; Simpson, RW; Spizzo, I; Widdop, RE | 1 |
| Chandrasekar, B; Delafontaine, P; Fay, WP; Krenz, M; Somanna, NK; Valente, AJ | 1 |
| Chen, C; Li, R; Manso, AM; Ross, RS | 1 |
| Dikalov, SI; Dikalova, AE | 1 |
| Boeynaems, JM; Hirano, K; Ide, T; Inoue, K; Kurose, H; Nishida, M; Nishimura, A; Numaga-Tomita, T; Robaye, B; Shimauchi, T; Sunggip, C; Tozaki-Saitoh, H; Tsuda, M | 1 |
| Lei, Y; Liu, JG; Wang, Y; Yang, J | 1 |
| Seawright, JW; Trache, A; Wilson, E; Woodman, CR | 1 |
| Harvey, A; Lopes, RA; Montezano, AC; Rios, F; Touyz, RM | 1 |
| Borrajo, A; Diaz-Ruiz, C; Garrido-Gil, P; Labandeira-Garcia, JL; Rodriguez-Perez, AI | 1 |
| Ban, TH; Chang, YS; Choi, BS; Jang, IA; Kim, EN; Kim, MY; Lim, JH; Park, CW; Shin, SJ; Yoon, HE | 1 |
| Campbell, KH; Choi, I; Corr, SA; Fisher, PA; Gardner, DS; Gutierrez, CG; Lee, JH; Rathbone, AJ; Sinclair, KD | 1 |
| Arjmandi, BH; Feresin, RG; Huang, J; Klarich, DS; Pourafshar, S; Salazar, G; Zhao, Y | 1 |
| Ashpole, NM; Ballabh, P; Csiszar, A; Gautam, T; Giles, CB; Sonntag, WE; Tarantini, S; Toth, P; Tucsek, Z; Ungvari, Z; Valcarcel-Ares, MN; Wei, JY; Wren, JD | 1 |
| Chen, HZ; Fu, WY; Gao, P; Han, L; Liu, DP; Liu, Y; Lu, J; Pei, JF; Tang, X; Wang, F; Wang, XM; Xu, TT; Yan, YF; Zhang, R; Zhang, ZQ; Zou, MH | 1 |
| Gnudi, L; Maltese, G; Mann, GE; Psefteli, PM; Rizzo, B; Siow, RC; Srivastava, S | 1 |
| Costa, G; Dantas, AP; Garabito, M; Jiménez-Altayó, F; Onetti, Y; Sabate, M; Vila, E | 1 |
| Aleligne, Y; Froogh, G; Huang, A; Kandhi, S; Le, Y; Pinto, JT; Sun, D | 1 |
| Jurado Acosta, A; Komati, H; Moilanen, AM; Nemer, M; Ruskoaho, H; Rysä, J; Szabo, Z | 1 |
| Ashpole, N; Csiszar, A; Fulop, GA; Gautam, T; Giles, CB; Sonntag, WE; Springo, Z; Tarantini, S; Ungvari, Z; Valcarcel-Ares, NM; Wren, JD; Yabluchanskiy, A | 1 |
| Broxson, CS; Erdem, A; Erdem, SR; Erdös, B; Tümer, N | 1 |
| Acosta, E; Avila, J; Naftolin, F; Palumbo, A; Peña, O | 1 |
| Borst, SE; Giovannini, S; Leeuwenburgh, C; Marzetti, E | 1 |
| Bai, XJ; Li, H; Liu, Q; Wang, NF | 1 |
| Costa, CA; Criddle, DN; Espinoza, LA; Marins de Carvalho, LC; Ognibene, DT; Oliveira, PR; Resende, AC; Soares de Moura, R; Tano, T | 1 |
| Horiuchi, M; Iwai, M; Min, LJ; Mogi, M | 1 |
| Fukumoto, M; Hayashi, T; Ikeda, T; Jin, D; Kitaura, Y; Miyazaki, M; Oku, H; Sugiyama, T; Takai, S | 1 |
| Elased, KM; Irigoyen, MC; Kanakamedala, K; Morris, M; Senador, D | 1 |
| Minamino, T | 1 |
| Didion, SP; Faraci, FM; Modrick, ML; Sigmund, CD | 1 |
| Lakatta, EG; Najjar, SS; Wang, M | 1 |
| Cole, RN; Everett, AD; Fu, Z; Gucek, M; Ingram, DK; Jiang, L; Khazan, B; Kolodgie, FD; Lakatta, EG; Liu, L; Mattison, J; Monticone, RE; Pintus, G; Sheng, S; Spinetti, G; Spurgeon, H; Telljohann, R; Van Eyk, JE; Virmani, R; Wang, M; Wu, J; Zhang, J | 1 |
| Albiston, AL; Burns, P; Chai, SY; Daswani, D; Diwakarla, S; Fernando, RN; Ng, L; Pham, V; Yeatman, HR | 1 |
| Li, YF; Shi, ST | 1 |
| Benigni, A; Cassis, P; Conti, S; Remuzzi, G | 1 |
| Ecelbarger, CM; Halagappa, VK; Li, L; Riazi, S; Tiwari, S | 2 |
| Crespo, MJ; Escobales, N; Ramos, JA; Santacana, GE | 1 |
| Dworakowski, R; Lakatta, EG; Shah, AM; Walker, SJ; Wang, M; Zhang, J | 1 |
| Adler, GK; Garg, R; Hopkins, PN; Hurwitz, S; Williams, GH | 1 |
| Chen, W; Frangogiannis, NG | 1 |
| Basgut, B; Cardounel, AJ; Cudykier, I; Erdos, B; Tawil, R; Tümer, N; Whidden, M; Woods, M | 1 |
| Haghikia, A; Hilfiker-Kleiner, D; Hoch, M; Stapel, B | 1 |
| Bradley, TJ; Cherney, DZ; Dekker, MG; Lai, V; Miller, JA; Reich, HN; Scholey, JW; Sochett, EB; Zinman, B | 1 |
| Angeli, F; Garofoli, M; Gentile, G; Martire, P; Mazzotta, G; Reboldi, G; Verdecchia, P | 1 |
| Benigni, A; Cassis, P; Remuzzi, G | 1 |
| Curtis, KS | 1 |
| Beltz, TG; Johnson, AK; Thunhorst, RL | 1 |
| Dell, KM; Goto, M; Hoxha, N; Osman, R | 1 |
| Ghee, JY; Han, DH; Kim, S; Kobori, H; Kuro-o, M; Ohashi, N; Piao, S; Song, JH; Yang, CW; Yoon, HE | 1 |
| Czabanka, M; Eklund, L; Heljasvaara, R; Ilves, M; Janmey, P; Kerkelä, R; Leskinen, H; Peuhkurinen, K; Pihlajaniemi, T; Piuhola, J; Rasi, K; Ruskoaho, H; Rysä, J; Sormunen, R; Vajkoczy, P; Vuolteenaho, O | 1 |
| Guerra, MJ; Labandeira-Garcia, JL; Rodriguez-Perez, AI; Valenzuela, R; Villar-Cheda, B | 1 |
| Abadir, PM | 1 |
| Auger, C; Bronner, C; Dal-Ros, S; Geny, B; Keller, N; Lang, AL; Schini-Kerth, VB; Zoll, J | 1 |
| Choi, YJ; Chung, HY; Ha, YM; Heo, HS; Kim, JM; Lee, EK; Ye, BH; Yu, BP | 1 |
| Arnold, AC; Diz, DI; Isa, K; Nautiyal, M; Shaltout, HA; Tallant, EA | 1 |
| Carter, CS; Choi, YJ; Chung, HY; Heo, HS; Kim, JM; Leeuwenburgh, C; Mi Ha, Y; Seo, AY; Ye, BH; Yu, BP | 1 |
| Guntani, A; Itoh, H; Iwasa, K; Katusic, ZS; Kyuragi, R; Maehara, Y; Matsumoto, T; Onohara, T | 1 |
| Borges, R; Cambiucci, EC; Ciampone, S; de Lima, IP; Gontijo, JA; Mesquita, FF | 1 |
| Guerra, MJ; Joglar, B; Labandeira-Garcia, JL; Parga, JA; Rodriguez-Pallares, J | 1 |
| Choi, YJ; Chung, HY; Ha, YM; Kim, JM; Uehara, Y; Ye, BH; Yu, BP | 1 |
| Dikalov, S | 1 |
| Bindom, S; Feng, Y; Gurley, SB; Lazartigues, E; Navar, LG; Seth, D; Suda, S; Xia, H | 1 |
| Boon, RA; Brandes, RP; Dimmeler, S; Essers, J; Fischer, A; Hergenreider, E; Heydt, S; Horrevoets, AJ; Pilato, M; Rosenthal, N; Sciacca, S; Seeger, T; van Heijningen, P; Vinciguerra, M; Zeiher, AM | 1 |
| Ata, P; Turan, K | 1 |
| Azhar, M; Barnett, JV; Camenisch, TD; Conway, SJ; Doetschman, T; Granzier, HL; Heimark, RL; Runyan, RB | 1 |
| Furuhashi, M; Koyama, M; Maeda, T; Miura, T; Shimamoto, K; Tanaka, M; Togashi, N; Yoshida, H | 1 |
| Ebenezar, KK; Smith, FG; Wong, AK | 1 |
| Itoh, H; Sasamura, H | 1 |
| Bapat, A; Fishbein, MC; Karagueuzian, HS; Lee, JH; Nguyen, TP; Sovari, AA; Weiss, JN | 1 |
| Idris-Khodja, N; Schini-Kerth, V | 1 |
| Deng, HW; Diao, TY; Gu, SS; Hai, R; Li, XL; Wu, SY; Zhang, Y | 1 |
| Saavedra, JM | 1 |
| Behnke, BJ; Delp, MD; Dominguez, JM; Donato, AJ; Lesniewski, LA; Muller-Delp, J; Park, Y; Prisby, RD | 1 |
| Aires, RS; Cabral, EV; Luzardo, R; Nascimento, WS; Oliveira, FS; Paixão, AD; Silva, PA; Vieira-Filho, LD; Vieyra, A | 1 |
| Boer, PA; de Lima, MC; Gontijo, JA; Lopes, A; Mesquita, FF; Scabora, JE; Torres, D | 1 |
| Baylis, C | 2 |
| Barrett-O'Keefe, Z; Conklin, JD; Fjeldstad, AS; Ives, SJ; McDaniel, J; Morgan, DE; Reese, V; Richardson, RS; Runnels, S; Sander, M; Trinity, JD; Witman, MA; Wray, DW | 1 |
| Castro-Moreno, P; Del Valle-Mondragón, L; Hernández-Muñoz, R; Ibarra-Barajas, M; López-Guerrero, JJ; Pardo, JP; Pastelín-Hernández, G; Villalobos-Molina, R | 1 |
| Asghar, M; Chugh, G; Pokkunuri, I | 1 |
| Baile, G; Gambini, J; Gíménez, I; Llinas, MT; Reverte, V; Salazar, FJ; Tapia, A | 1 |
| Chen, GC; Duan, SB; Liu, GL; Pan, P; Wang, P; Xu, XQ | 1 |
| Chu, Y; Faraci, FM; Heistad, DD; Miller, JD; Mitchell, IJ; Peña Silva, RA; Penninger, JM | 1 |
| Loria, AS; Pollock, DM; Pollock, JS; Yamamoto, T | 1 |
| Begg, DP; Sinclair, AJ; Weisinger, RS | 1 |
| Davis, DD; Lima, R; Reckelhoff, JF; Yanes, LL | 1 |
| Liu, TC; Pu, HF | 1 |
| Antonijevic, IA; Golly, IC; Held, K; Künzel, H; Murck, H; Steiger, A; Uhr, M; Wetter, TC | 1 |
| Di Salvo, G; Natale, F; Ratti, G; Tedesco, MA | 1 |
| Fujimura, A; Harada, K; Ohmori, M | 1 |
| Baker, KM; Boheler, K; Dostal, DE; Lakatta, EG; Shivakumar, K | 1 |
| Jin, L; Linder, AE; Mills, TM; Webb, RC | 1 |
| Hayashi, A; Kawasaki, T; Kimoto, K; Matsui, T; Matsumoto, K; Murakami, K; Tamaya, K | 1 |
| Asai, K; Lakatta, EG; Natividad, FF; Resuello, RG; Takagi, G; Vatner, DE; Vatner, SF; Wang, M | 1 |
| Chowienczyk, PJ; Kelly, RP; Millasseau, SC; Ritter, JM | 1 |
| Moskowitz, DW | 1 |
| Ishizaka, N; Mitani, H; Nagai, R; Ohno, M; Saito, K | 1 |
| Lakatta, EG; Monticone, R; Spinetti, G; Wang, M; Zhang, J; Zhao, D | 1 |
| Oberhauser, V; Rump, LC; Sellin, L; Stegbauer, J; Vonend, O | 1 |
| Black, MJ; Jones, ES; Widdop, RE | 1 |
| Berk, BC; Blaxall, BC; Miano, JM | 1 |
| Basso, N; de Cavanagh, EM; del Rosario Lores Arnaiz, M; Ferder, L; Inserra, F; Paglia, N; Stella, I | 1 |
| Díez, J; Fortuño, MA; López, N | 1 |
| Carmona-Calero, EM; Castañeyra-Martín, M; Castañeyra-Perdomo, A; González-Marrero, I; Marrero-Gordillo, N; Martínez-Peña Y Valenzuela, I; Ormazabal-Ramos, C; Pérez-Garcia, CG; Pérez-González, H; Trujillano-Dorado, A | 1 |
| Booz, GW | 1 |
| Delbridge, LM; Domenighetti, AA; Egger, M; Pedrazzini, T; Richards, SM; Wang, Q | 1 |
| Johnson, RJ; Long, DA; Mu, W; Price, KL | 1 |
| Augusto Souza Dos Santos, R; da Silva Lemos, M; Nardoni Gonçalves Braga, A; Roberto da Silva, J | 1 |
| Cheng, L; Jiang, LQ; Krawczyk, M; Lakatta, EG; Monticone, R; Pintus, G; Spinetti, G; Talan, M; Wang, M; Zhang, J; Zhao, D | 1 |
| Basso, N; Cini, R; Inserra, F; Paglia, N; Terragno, NA | 1 |
| Arguinzoni, JK; Clarke, E; Haddad, GE; Scheer, A; Sobrian, SK | 1 |
| Bennett, CD; Carter, CS; Chappell, MC; Groban, L; Kitzman, DW; Pailes, NA; Sonntag, WE | 1 |
| Higuchi, R; Miyawaki, M; Okutani, T; Yoshikawa, N | 1 |
| Ishihata, A; Katano, Y | 1 |
| Barton, M; Kretz, M; Mundy, AL; Widmer, CC | 1 |
| Komuro, I; Minamino, T | 1 |
| Dulger, H; Erbilen, E; Guler, N; Gumrukcuoglu, HA; Kutay, V; Ozkara, C; Sahin, M | 1 |
| Hershey, SH; Nibbelink, KA; Simpson, RU | 1 |
| Llinas, MT; Loria, A; Reverte, V; Saez, F; Salazar, F; Salazar, FJ | 1 |
| Ishiguro, K; Itoh, H; Sakamaki, Y; Saruta, T; Sasamura, H | 1 |
| Backx, PH; Butany, J; Chappell, M; Kassiri, Z; Khokha, R; Oudit, GY; Patel, MP; Penninger, JM; Scholey, JW; Tsushima, RG | 1 |
| Basso, N; Cini, R; Ferder, L; Inserra, F; Pietrelli, A; Terragno, NA | 1 |
| Diz, DI; Gilliam-Davis, S; Kasper, SO; Payne, VS; Robbins, ME; Tommasi, EN | 1 |
| Chappell, MC; Gallagher, PE; Groban, L; Pendergrass, KD; Pirro, NT; Yamaleyeva, LM | 1 |
| Hase, N; Katsurada, A; Kobori, H; Miyata, K; Navar, LG; Ohashi, N; Ozawa, Y; Satou, R; Sigmund, CD; Suzaki, Y | 1 |
| Benter, IF; Kehinde, EO; Yousif, MH | 1 |
| de Cavanagh, EM; Ferder, L; Ferder, M; Inserra, F | 1 |
| Dusting, GJ; Jiang, F; Jones, GT | 1 |
| Adler, GK; Hopkins, PN; Ricchiuti, V; Seely, EW; Szmuilowicz, ED | 1 |
| Henrion, D; Jones, ES; Vinh, A; Widdop, RE | 1 |
| An, J; Dietz, R; Endres, M; Gertz, K; Harms, C; Hauck, L; Rohne, J; von Harsdorf, R | 1 |
| Arnold, AC; Diz, DI; Ferrario, CM; Ganten, D; Sakima, A | 1 |
| Anton, MM; Cook, JN; Cortez-Cooper, MY; Devan, AE; Neidre, DB; Tanaka, H | 1 |
| Harris, RA; Nishiyama, SK; Richardson, RS; Wray, DW | 1 |
| Lee, JH; Ragolia, L; Xia, S | 1 |
| Jiang, L; Lakatta, EG; Monticone, RE; Pintus, G; Spinetti, G; Telljohann, R; Wang, M; Zhang, J | 1 |
| Ciuffo, GM; Forneris, ML; Fuentes, LB; Sánchez, SI; Seltzer, AM | 1 |
| Drury, PL | 1 |
| Greenlees, KJ; Migally, N; Tucker, A; Wright, ML | 2 |
| Bailie, MD; Hook, JB; Wallace, KB | 1 |
| Dillon, MJ | 1 |
| Odell, WD; Parker, LN | 1 |
| Bailie, MD; Oparil, S; Wallace, KB | 1 |
| Doussau, MP; Giudicelli, JF; Richer, C | 1 |
| Ayres, NA; Gomez, RA; Lawton, WJ; Robillard, JE; VanOrden, DE; Weismann, DN | 1 |
| Giese, J; Skøtt, P | 1 |
| Amery, AK; Lynen, PJ; Scharpé, SL; Van Acker, KJ | 1 |
| Epstein, AN | 1 |
| Rösler, A | 1 |
| Polgar, P; Schneider, E; Smith, J; Taylor, L | 1 |
| Csaba, IF; Ertl, T; Sulyok, E; Varga, F | 1 |
| Eguchi, T; Hayashi, M; Kato, E; Saruta, T; Suzuki, A; Yasui, T | 1 |
| Laragh, JH; Niarchos, AP | 1 |
| Koster, M | 1 |
| Kigoshi, T; Miyamoto, M; Morimoto, S; Morise, T; Takeda, R; Takimoto, H; Uchida, K | 1 |
| Broughton Pipkin, F; O'Callaghan, M; Smales, OR | 1 |
| Carey, RM; Kaiser, DL; Peach, MJ; Wilson, TA; Wright, EM | 1 |
| Adlin, EV; Channick, BJ; Marks, AD | 1 |
| Julius, S; Schoeps, P; Shulak, JM; Vander, AJ; Victery, W | 1 |
| Baxter, CR; Duggin, GG; Horvath, JS; Tiller, DJ | 1 |
| Berecek, KH; Gross, F; Schwertschlag, U | 1 |
| Bailie, MD; Hook, JB; Osborn, JL | 1 |
| Couture, R; Regoli, D | 2 |
| Beretta-Piccoli, C; Glück, Z; Grimm, M; Gübelin, U; Keusch, G; Meier, A; Minder, I; Weidmann, P | 1 |
| el-Dahr, SS; Yosipiv, IV | 2 |
| Epstein, AN; Galaverna, O; Nicolaïdis, S; Sakai, RR; Yao, SZ | 1 |
| Miller, JM; Nakashima, T; Nuttall, AL | 1 |
| Bertram, JF; Black, MJ; Campbell, GR; Campbell, JH | 1 |
| Kuttan, SC; Sim, MK | 1 |
| Fulton, JD; Howie, KA; MacDonald, E; McDonald, A; Scott, PJ; Wadsworth, RM | 1 |
| Cai, G; Gurdal, H; Johnson, MD; Seasholtz, TM | 1 |
| Higaki, J; Mikami, H; Nagano, M; Ogihara, T | 1 |
| Benzoni, D; Boussairi, EH; Sacquet, J; Sassard, J | 1 |
| Anderson, S; Houghton, DC; Tank, JE; Vora, JP | 1 |
| Bowsher, RR; Cobb, SL; Voelker, JR | 1 |
| Caffari, G; Caiazza, A; Capretti, L; Chiodera, P; Coiro, V; Marchesi, M; Rossi, G; Volpi, R | 1 |
| Becú-Villalobos, D; Díaz-Torga, GS; Libertun, C | 1 |
| Cassis, LA | 1 |
| Hogikyan, RV; Supiano, MA | 1 |
| Barry, WH; Hirata, Y; Ikenouchi, H; Kohmoto, O; Momomura, S; Serizawa, T | 1 |
| Duggan, J; Kilfeather, S; Nussberger, J; O'Malley, K | 1 |
| Bartenbach, S; Gohlke, P; Kuwer, I; Lamberty, V; Linz, W; Schnell, A; Schölkens, BA; Unger, T; Wiemer, G | 1 |
| Herzer, WA; Jackson, EK | 1 |
| Ganten, D; Ganten, U; Hilgers, KF; Luft, FC; Mai, M; Mann, JF; Veelken, R | 1 |
| Brudieux, R; Rakotondrazafy, J | 1 |
| Baumbach, GL; Hajdu, MA; Heistad, DD; McElmurry, RT | 1 |
| Finn, WL; Gordon, RD; Klemm, SA; Ryan, SJ; Tunny, TJ | 1 |
| Ciuffo, GM; Saavedra, JM; Seltzer, AM; Tsutsumi, K; Viswanathan, M | 1 |
| Jiménez, E; Matilla, MJ; Montiel, M | 1 |
| Aperia, A; Eklöf, AC; Ostlund, EV | 1 |
| Corman, B; Dupont, M; Geelen, G; Jover, B; Mimran, A; Wahba, W | 1 |
| Hasegawa, K; Khosla, MC; Nishimura, H | 1 |
| Lloyd, MC; Traub, O; Webb, RC | 1 |
| al-Subaili, M; Cleland, JG; Dutka, DP; Impallomeni, M; Nihoyannopoulos, P; Oakley, CM; Olivotto, I; Ward, S | 1 |
| Pratt, RE; Zhang, J | 1 |
| Fogo, A; Ichiki, T; Inagami, T; Kakuchi, J; Labosky, PA; Naftilan, AJ; Niimura, F; Oikawa, T; Okubo, S; Yoshida, H | 1 |
| Aoki, M; Higaki, J; Kaneda, Y; Morishita, R; Ogihara, T; Tomita, N; Tomita, S | 1 |
| Li, C; Li, L; Li, X; Lü, X; Wang, H | 1 |
| Buñag, RD; Davidow, LW | 1 |
| Del Bianco, A; Fregly, MJ; Rowland, NE | 1 |
| Breault, L; Gallo-Payet, N; Lehoux, JG | 1 |
| Konishi, C; Naito, Y; Ohara, N; Ono, H; Saito, Y | 1 |
| Yamazaki, T; Yazaki, Y | 1 |
| Callahan, P; Janik, JM; Robinson, EO; Shen, J | 1 |
| Pinto, A; Sorrentino, R | 1 |
| Baylis, C; Engels, K; Hymel, A; Navar, LG | 1 |
| Baylis, C; Qiu, C; Zhang, XZ | 1 |
| Ancellin, N; Barrault, MB; Corman, B; Horgen, L; Klingler, C; Lluel, P; Preisser, L; Teillet, L | 1 |
| Sen, S; Sil, P | 1 |
| Buñag, RD; Kerecsen, L; Mellick, JR; Montemayor, E | 1 |
| Lantelme, P; Lo, M; Luttenauer, L; Sassard, J | 1 |
| Higaki, J; Kida, I; Matsumoto, K; Moriguchi, A; Morishita, R; Nakamura, T; Nakano, N; Ogihara, T; Tomita, N | 1 |
| Gillies, LK; Lee, RM; Lu, M; Wang, H | 1 |
| Beierwaltes, WH; Garvin, JL | 1 |
| d'Uscio, LV; Lüscher, TF; Moreau, P | 1 |
| Chevalier, B; Heymes, C; Levy, BI; Llorens-Cortes, C; Marotte, F; Samuel, JL; Silvestre, JS; Swynghedauw, B | 1 |
| Bernareggi, M; Berti, F; De Gennaro Colonna, V; Müller, EE; Polvani, GL; Rossoni, G | 1 |
| Aikawa, M; Fujita, M; Ibukiyama, C; Matsuoka, O; Saiki, T; Takazawa, K; Tamura, S; Tanaka, N | 1 |
| Nowicki, PT | 1 |
| Rasch, R; Woods, LL | 1 |
| Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
| Fujimura, H; Nishiyama, S; Ohmachi, Y; Okumura, F; Toriumi, W; Yoneda, H | 1 |
| Daubert, DL; Meadows, GG; Sanchez, PJ; Speth, RC; Wang, JH | 1 |
| Amado, JA; Berrazueta, JR; Fernández, C; García-Unzueta, MT; Montalbán, C; Ochoteco, A; Peña, N; Poveda, JJ | 1 |
| Endemann, D; He, G; Li, JS; Schiffrin, EL; Touyz, RM | 1 |
| Minnich, LA; Nowicki, PT | 1 |
| Aldini, G; Berti, F; Bombardelli, E; Carini, M; Facino, RM; Morazzoni, P; Rossoni, G | 1 |
| Galecki, AT; Hogikyan, RV; Krueger, JL; Sidani, MA; Supiano, MA | 1 |
| Allen, B; Buñag, R; Mellick, J | 1 |
| Takeda, Y | 1 |
| Bennett, WM | 1 |
| Ferri, C; Fisher, ND; Hollenberg, NK; Hurwitz, S; Jeunemaitre, X; Williams, GH | 1 |
| Collins, T; Deguchi, J; Makuuchi, M; Nakaoka, T; Takuwa, Y | 1 |
| Chen, JJ; Cho, WL; Kau, MM; Wang, PS; Wang, SW | 1 |
| Doi, K; Ishihata, A; Katano, Y; Nakamura, M; Ono, A; Tasaki, K | 1 |
| Cachofeiro, V; Lahera, V; Maeso, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
| Abernethy, DR; Andrawis, N; Jones, DS | 1 |
| Kihara, M; Mitsui, Y; Nakasaka, Y; Schmelzer, JD; Takahashi, M | 1 |
| Dworkin, LD; Feiner, HD; Tolbert, EM; Weisstuch, J | 1 |
| Capretti, L; Cataldo, S; Chiodera, P; Coiro, V; Pilla, S; Volpi, R | 1 |
| Fukamizu, A | 1 |
| Carlson, J; Hedner, J; Kraiczi, H; Peker, Y | 1 |
| Abe, I; Fujii, K; Fujishima, M; Goto, K; Onaka, U | 1 |
| Anderson, S; Mader, SL; Reed, JF; Roullet, JB; Schutzer, WE; Xue, H | 1 |
| Blanton, CA; Blevins, JE; Hamilton, JS; Hernandez, EJ; Horwitz, BA; McDonald, RB | 1 |
| Aerni, JD; Cespedes, AT; Katovich, MJ; Rowland, NE | 1 |
| Asai, K; Kudej, AB; Kudej, RK; Natividad, F; Shen, YT; Takagi, G; Vatner, DE; Vatner, SF | 1 |
| Azizi, M; Corvol, P; Giacché, M; Hopkins, PN; Hunt, SC; Jeunemaitre, X; Vedie, B; Vuagnat, A; Williams, GH | 1 |
| Boesch, DM; Garvin, JL | 1 |
| Basso, N; González Bosc, LV; Kurnjek, ML; Müller, A; Terragno, NA | 1 |
| Ha, JH; Jin, DQ; Lee, ES; Moon, HG; Park, YH; Shin, SM | 1 |
| Bakala, H; Corman, B; Gouraud, S; Ribière, P; Teillet, L | 1 |
| Corvol, P; Lenkei, Z; Llorens-Cortés, C; Nuyt, AM; Palkovits, M | 1 |
| de Lima, J; De Myttenaere-Bursztein, S; Maxwell, MH; Weidmann, P | 1 |
| Bühler, FR | 1 |
| Bühler, FR; Lütold, BE | 1 |
| Baig, H; Kerkhof, P; Manders, WT; Mirsky, I; Pagani, M; Vatner, SF | 1 |
| Baxter, C; Duggin, G; Horvath, J; Tiller, D | 1 |
| Amery, A; Bulpitt, C; Conway, J; Fagard, R; Lijnen, P; Reybrouck, T; Wasir, H | 1 |
| Bailie, MD; Hook, JB | 1 |
| Jimbo, S; Kuchi, M; Masuyama, Y; Nishimura, T; Nishio, I; Ohtani, H | 1 |
| Beevers, DG; Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Lever, AF; Mason, P; Neville, AM; Robertson, JI | 1 |
| Bumpus, FM; Khairallah, PA; Khosla, MC; Muñoz-Ramírez, H | 1 |
| Breuer, H; Kaulhausen, H; Kley, HK | 1 |
| Aharon, NV; Davis, JO; Freeman, RH; Ulick, S; Weinberger, MH | 1 |
| Epstein, M; Hollenberg, NK | 1 |
| Dupont, J; Sassard, J; Vincent, M | 1 |
| Collie, MA; Cronshaw, J; Holmes, WN | 1 |
| Duggan, J; Kilfeather, S; Nussberger, J; O'Brien, E; O'Malley, K | 1 |
| Iwase, M; Kuro-o, M; Nagai, R; Nakahara, K; Nishimura, H; Ohkubo, A; Takewaki, S; Yazaki, Y | 1 |
| Gesek, FA; Schoolwerth, AC | 1 |
| Aguilera, G; Catt, KJ; Jacobowitz, DM; Millan, MA | 1 |
| Buñag, RD; Teräväinen, TL | 1 |
| Henrich, WL; Levi, M | 1 |
| Fukui, T; Horio, T; Kohno, M; Murakawa, K; Takeda, T; Yasunari, K; Yokokawa, K | 1 |
| Rajasekaran, AK; Sen, I | 1 |
| Saavedra, JM; Tsutsumi, K | 2 |
| Correa, FM; Saavedra, JM; Tsutsumi, K; Viswanathan, M | 1 |
| Bosman, FT; Daemen, MJ; Lombardi, DM; Schwartz, SM | 1 |
| Buhi, WC; Ogilvie, S; Olson, JA; Raizada, MK; Shiverick, KT | 1 |
| Abe, Y; Iwao, H | 1 |
| Hosoi, M; Kim, S; Shimamoto, K; Takada, T; Yamamoto, K | 1 |
| Wen, S | 1 |
| Hatake, K; Kurahashi, M; Sakamoto, K; Wakabayashi, I; Yoshimoto, S | 1 |
| Ball, D; Elliott, ME; Goodfriend, TL; Siebers, MJ | 1 |
| Jimenez, AE; Passmore, JC | 1 |
| Anderson, GH; Streeten, DH; Wagner, S | 1 |
| Goodfriend, TL; Potter, CL | 1 |
| Kalliatakis, B; Patton, J; Radford, HM; Rosendorff, C | 1 |
| Myers, LM; Raizada, MK; Sumners, C | 1 |
| Jackson, EK | 1 |
| Khananashvili, IaA | 1 |
| Aber, GM; Messenger, EA; Stonier, C | 1 |
| Coleman, TG; Guyton, AC; Hall, JE | 1 |
| Flood, JF; Morley, JE | 1 |
| Ajayi, AA; Reid, JL | 1 |
| Harris, PJ; Morgan, TO; Thomas, D | 1 |
| Nelson, DO | 1 |
| Khairallah, PA; Upsher, ME | 1 |
| Gomazkov, OA; Komissarova, NV; Panfilov, AD; Petriĭ, OP | 1 |
| Wilkes, BM | 1 |
| Epstein, AN; Leshem, M | 1 |
| Allaerts, W; Baes, M; Denef, C | 1 |
| Ghiani, P; Mandich, A; Masini, MA; Uva, BM | 1 |
| Bian, K; Inoue, S; Toda, N | 1 |
| Aguilera, G; Millan, MA | 1 |
| Campbell, R; Conlon, ME; Egan, B; Julius, S; Schork, N; Zwiefler, A | 1 |
| Lennon, EA; Poyser, NL | 1 |
| Shimizu, I; Toda, N | 1 |
| Asinova, MI; Ershova, GS; Korkushko, OV | 1 |
| Owen, TL | 1 |
| Freis, ED; Heath, WC; Luchsinger, PC; Snell, RE | 1 |
| Sokabe, H | 1 |
| Buckley, JP; Hageman, WE | 1 |
| Levin, K | 1 |
| Downing, SE; Karpeles, LM; Lee, JC | 1 |
| Coburn, JW; Massry, SG; Maxwell, MH; Reinhart, R; Rowe, P; Weidmann, P | 1 |
| Fukuchi, Y | 1 |
| Abrams, HL; Adams, DF; Hollenberg, NK; Merrill, JP; Rashid, A; Solomon, HS | 1 |
| Mott, JC | 1 |
| Campbell, BA; Friedman, MI | 1 |
| Lowenthal, DT | 1 |
52 review(s) available for angiotensin ii and Aging
| Article | Year |
|---|---|
Is the anti-aging effect of ACE2 due to its role in the renin-angiotensin system?-Findings from a comparison of the aging phenotypes of ACE2-deficient, Tsukuba hypertensive, and Mas-deficient mice.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Mice; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2023 |
Effect of renin-angiotensin system on senescence.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Cellular Senescence; Humans; Longevity; Mice; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System; Signal Transduction | 2020 |
Targeting Molecular Mechanism of Vascular Smooth Muscle Senescence Induced by Angiotensin II, A Potential Therapy via Senolytics and Senomorphics.
Topics: Aging; Angiotensin II; Animals; Cardiovascular Diseases; Cellular Senescence; Humans; Molecular Targeted Therapy; Myocytes, Smooth Muscle; Renin-Angiotensin System | 2020 |
Kidney and epigenetic mechanisms of salt-sensitive hypertension.
Topics: Aging; Aldosterone; Angiotensin II; Animals; DNA Methylation; Fetal Nutrition Disorders; Glucuronidase; Humans; Hypertension; Klotho Proteins; Obesity; Oxidative Stress; Receptors, Mineralocorticoid; Renal Circulation; Sodium Chloride, Dietary; Wnt Signaling Pathway | 2021 |
Endocrine and metabolic aspects of COVID-19.
Topics: Aging; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Diabetes Mellitus; Humans; Melatonin; Obesity; Renin-Angiotensin System | 2021 |
Role of Melatonin in Angiotensin and Aging.
Topics: Aging; Angiotensin II; Antioxidants; DNA Damage; Free Radicals; Humans; Melatonin; Mitochondria; Oxidative Stress; Reactive Oxygen Species | 2021 |
Purinergic P2Y
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Humans; Hypertension; Isothiocyanates; Molecular Targeted Therapy; Purinergic P2 Receptor Antagonists; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Purinergic P2; Thiourea | 2017 |
Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease.
Topics: Aging; Aldosterone; Angiotensin II; Animals; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Carotid Arteries; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Mice; Muscle, Smooth, Vascular; Placenta Growth Factor; Pregnancy Proteins; Receptors, Mineralocorticoid; Signal Transduction | 2013 |
Proinflammation: the key to arterial aging.
Topics: Aged; Aging; Angiotensin II; Animals; Antigens, Surface; Arteries; Arteritis; Atherosclerosis; Calpain; Chemokine CCL2; Endothelin-1; Humans; Hypertension; Inflammation; Inflammation Mediators; Matrix Metalloproteinase 2; Middle Aged; Milk Proteins; Muscle, Smooth, Vascular; Nitric Oxide; Reactive Oxygen Species; Receptors, CCR2; Transforming Growth Factor beta1 | 2014 |
Proinflammation of aging central arteries: a mini-review.
Topics: Aging; Angiotensin II; Animals; Arteries; Atherosclerosis; Haplorhini; Humans; Hypertension; Myocytes, Smooth Muscle; Rabbits; Rats; Signal Transduction; Tunica Intima; Tunica Media; Vascular Remodeling | 2014 |
Angiotensin II blockade: how its molecular targets may signal to mitochondria and slow aging. Coincidences with calorie restriction and mTOR inhibition.
Topics: Aging; Angiotensin II; Caloric Restriction; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glucuronidase; Humans; Klotho Proteins; Longevity; Mechanistic Target of Rapamycin Complex 1; Mitochondria; Multiprotein Complexes; Receptors, Calcitriol; Renin-Angiotensin System; Signal Transduction; Sirtuins; TOR Serine-Threonine Kinases; Vitamin D | 2015 |
Integrins and integrin-related proteins in cardiac fibrosis.
Topics: Age Factors; Aging; Angiotensin II; Animals; Blood Pressure; Carrier Proteins; Cytokines; Diabetic Cardiomyopathies; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Integrins; Molecular Targeted Therapy; Myocardial Infarction; Myocardium; Protein Binding; Stress, Mechanical | 2016 |
Contribution of mitochondrial oxidative stress to hypertension.
Topics: Aging; Angiotensin II; Animals; Caloric Restriction; Humans; Hypertension; Mitochondria; Motor Activity; Oxidative Stress; Reactive Oxygen Species; Sirtuin 3; Smoking; Superoxide Dismutase | 2016 |
Vascular Fibrosis in Aging and Hypertension: Molecular Mechanisms and Clinical Implications.
Topics: Aging; Angiotensin II; Endothelin-1; Endothelium, Vascular; Fibrosis; Humans; Hypertension; Matrix Metalloproteinases; Risk Factors; Smad Proteins; Transforming Growth Factor beta1; Vascular Stiffness | 2016 |
Modulation of GH/IGF-1 axis: potential strategies to counteract sarcopenia in older adults.
Topics: Aged; Aging; Angiotensin II; Body Weight; Growth Hormone; Humans; Hypothalamus; Insulin-Like Growth Factor I; Models, Biological; Muscle, Skeletal; Muscles; Muscular Atrophy | 2008 |
Signaling mechanisms of angiotensin II in regulating vascular senescence.
Topics: Aging; Aldosterone; Angiotensin II; Animals; Humans; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Vascular Diseases | 2009 |
[Role of the renin-angiotensin system in the regulation of vascular senescence].
Topics: Aging; Angiotensin II; Animals; Blood Vessels; Cellular Senescence; Humans; Renin-Angiotensin System | 2009 |
Arterial aging and subclinical arterial disease are fundamentally intertwined at macroscopic and molecular levels.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Angiotensin II; Animals; Coronary Artery Disease; Coronary Vessels; Endothelium, Vascular; Female; Humans; Hypertension; Male; Risk Factors | 2009 |
Angiotensin receptors as determinants of life span.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Longevity; Mitochondria; Oxidative Stress; Receptors, Angiotensin; Renin-Angiotensin System; Sirtuin 3; Sirtuins | 2010 |
Arterial aging: a journey into subclinical arterial disease.
Topics: Aging; Angiotensin II; Animals; Arteries; Atherosclerosis; Humans; Signal Transduction; Vascular Diseases | 2010 |
The role of inflammatory and fibrogenic pathways in heart failure associated with aging.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Angiotensin II; Fibroblasts; Fibrosis; Heart Failure, Diastolic; Humans; Inflammation; Muscle Cells; Phagocytes; Reactive Oxygen Species; Risk Factors; Transforming Growth Factor beta; United States; Ventricular Remodeling | 2010 |
STAT3 and cardiac remodeling.
Topics: Aging; Angiotensin II; Cardiomyopathy, Dilated; Extracellular Matrix; Humans; Inflammation; Mitochondria; Myocardium; Myocytes, Cardiac; Signal Transduction; STAT3 Transcription Factor; Ventricular Remodeling | 2011 |
Aliskiren versus ramipril in hypertension.
Topics: Aging; Amides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Diabetic Angiopathies; Fumarates; Half-Life; Humans; Hypertension; Ramipril; Renin-Angiotensin System | 2010 |
Angiotensin II revisited: new roles in inflammation, immunology and aging.
Topics: Aging; Angiotensin II; Autoimmunity; Humans; Inflammation; Oxidative Stress; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 2010 |
Angiotensin II blockade: a strategy to slow ageing by protecting mitochondria?
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Caloric Restriction; Gene Expression; Glucuronidase; Humans; Klotho Proteins; Mitochondria; Models, Biological; Oxidants; Peroxisome Proliferator-Activated Receptors; Reactive Oxygen Species; Renin-Angiotensin System; Sirtuins | 2011 |
Angiotensin peptides and central autonomic regulation.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Brain; Humans; Hypertension; MAP Kinase Signaling System; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol 3-Kinases | 2011 |
Cross talk between mitochondria and NADPH oxidases.
Topics: Aging; Angiotensin II; Animals; Antioxidants; Atherosclerosis; Diabetes Mellitus; Humans; Hypertension; Mice; Mitochondria; NADPH Oxidases; Neurodegenerative Diseases; Nitric Oxide Synthase Type III; Organophosphorus Compounds; Oxidation-Reduction; Oxidative Stress; Piperidines; Rabbits; Rats; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Xanthine Oxidase | 2011 |
Transforming growth factor beta signaling in adult cardiovascular diseases and repair.
Topics: Aging; Angiotensin II; Animals; Cardiac Rehabilitation; Cardiovascular Diseases; Epithelial-Mesenchymal Transition; Gene Expression; Genetic Variation; Humans; Mitogen-Activated Protein Kinases; Mutation; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad Proteins; Transforming Growth Factor beta | 2012 |
Angiotensin II AT(1) receptor blockers as treatments for inflammatory brain disorders.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Brain; Brain Diseases; Brain Injuries; Brain Ischemia; Humans; Inflammation; Mood Disorders; Neurodegenerative Diseases; Neuroprotective Agents; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Factors; Stress, Physiological; Stroke | 2012 |
Sexual dimorphism: the aging kidney, involvement of nitric oxide deficiency, and angiotensin II overactivity.
Topics: Aged; Aging; Androgens; Angiotensin II; Animals; Female; Glomerular Filtration Rate; Humans; Kidney Glomerulus; Male; Nitric Oxide; Oxidative Stress; Sex Characteristics | 2012 |
Renal dopamine and angiotensin II receptor signaling in age-related hypertension.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Dopamine; Humans; Hypertension; Kidney; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Dopamine D1; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2013 |
Does the angiotensin II receptor antagonist losartan improve cognitive function?
Topics: Aged; Aged, 80 and over; Aging; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Clinical Trials as Topic; Cognition Disorders; Humans; Hypertension; Losartan | 2002 |
Inhibition of the tonic contraction in the treatment of erectile dysfunction.
Topics: Adrenergic Agonists; Adult; Aged; Aging; Amides; Angiotensin II; Calcium Signaling; Cyclic AMP; Endothelin-1; Erectile Dysfunction; Forecasting; Humans; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Penis; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoactive Intestinal Peptide | 2003 |
Pathophysiologic implications of angiotensin I-converting enzyme as a mechanosensor: diabetes.
Topics: Aging; Angiotensin II; Animals; Blood Vessels; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Heart Diseases; Humans; Insulin Resistance; Mechanoreceptors; Peptidyl-Dipeptidase A | 2003 |
Protective effect of the inhibition of the renin-angiotensin system on aging.
Topics: Aging; Angiotensin II; Animals; Behavior; Behavior, Animal; Cardiovascular Physiological Phenomena; Humans; Learning; Renin-Angiotensin System | 2005 |
Blood vessels and the aging kidney.
Topics: Aging; Angiotensin II; Animals; Biological Factors; Blood Vessels; Humans; Kidney; Models, Biological; Neovascularization, Physiologic; Nitric Oxide; Vascular Endothelial Growth Factor A; Vasomotor System | 2005 |
Effect of omapatrilat on the aging process of the normal rat.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Atrial Natriuretic Factor; Cardiovascular System; Cognition; Inflammation; Kidney; Nitric Oxide Synthase; Protease Inhibitors; Pyridines; Rats; Renin-Angiotensin System; Thiazepines; Vasoconstriction; Vasodilation | 2005 |
Vascular cell senescence: contribution to atherosclerosis.
Topics: Aging; Aging, Premature; Angiotensin II; Animals; Atherosclerosis; Blood Vessels; Cellular Senescence; Diabetic Angiopathies; DNA Damage; Humans; Mitochondria; Oxidative Stress; Syndrome; Telomere | 2007 |
From mitochondria to disease: role of the renin-angiotensin system.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Diabetes Mellitus; Humans; Hypertension; Mitochondria; Mitochondrial Diseases; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2007 |
Vascular angiotensin AT2 receptors in hypertension and ageing.
Topics: Aging; Angiotensin II; Blood Vessels; Humans; Hypertension; Receptor, Angiotensin, Type 2 | 2008 |
Diabetes and arterial hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Diuretics; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Obesity; Renin; Sodium; Systole; Vascular Diseases | 1983 |
Control of adrenal androgen secretion.
Topics: Adolescent; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Androgens; Angiotensin II; Animals; beta-Lipotropin; Child; Child, Preschool; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Estrogens; Fasting; Female; Gonadotropins; Growth Hormone; Hirsutism; Humans; Hydrocortisone; Infant; Male; Middle Aged; Prolactin; Prostaglandins; Puberty; Stress, Physiological | 1980 |
Age and the renin-angiotensin system.
Topics: Adolescent; Adult; Aged; Aging; Angiotensin II; Child; Child, Preschool; Humans; Hypertension; Infant; Infant, Newborn; Middle Aged; Renin; Renin-Angiotensin System | 1983 |
The ontogeny of neurochemical systems for control of feeding and drinking.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Deoxyglucose; Drinking Behavior; Eating; Feeding Behavior; Injections, Intraventricular; Nervous System; Nervous System Physiological Phenomena; Norepinephrine; Rats; Sucking Behavior | 1984 |
19-Noraldosterone.
Topics: Age Factors; Aging; Aldosterone; Angiotensin II; Animals; Corticosterone; Hyperaldosteronism; Mass Spectrometry; Rats; Renin; Time Factors | 1999 |
Drug-related renal dysfunction in the elderly.
Topics: Aging; Aminoglycosides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Hormone Antagonists; Humans; Immunosuppressive Agents; Kidney Diseases | 1999 |
[A role of angiotensin II found in knockout mice with angiotensin signal breakdown].
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cardiovascular Diseases; Humans; Hypertension; Mice; Mice, Knockout; Nerve Regeneration; Renin-Angiotensin System; Risk Factors | 2000 |
Aging and the cardiovascular system.
Topics: Aged; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Cardiac Output; Cerebrovascular Disorders; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Regional Blood Flow; Renin; Stroke Volume; Vascular Resistance | 1978 |
Perinatal renal pharmacology.
Topics: Aging; Angiotensin II; Anions; Biological Transport, Active; Diuretics; Hemodynamics; Humans; Infant, Newborn; Kidney; Lipid Metabolism; Microsomes; p-Aminohippuric Acid; Prostaglandins; Protein Biosynthesis; Renin | 1979 |
[Expression of the renin and angiotensinogen genes].
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Dexamethasone; Gene Expression Regulation; Humans; Hypertension, Renovascular; Mice; Mice, Transgenic; Organ Specificity; Renin; Renin-Angiotensin System; RNA, Messenger | 1991 |
The renin-angiotensin system. Normal physiology and changes in older hypertensives.
Topics: Aging; Aldosterone; Angiotensin II; Blood Pressure; Humans; Hypertension; Natriuresis; Renin-Angiotensin System; Water-Electrolyte Imbalance | 1989 |
Tissue sensitivity to drugs in disease states.
Topics: Aging; Angiotensin II; Animals; Atropine; Bartter Syndrome; Bone and Bones; Carbohydrate Metabolism; Cardiovascular Diseases; Drug Hypersensitivity; Gastric Mucosa; Gastrointestinal Diseases; Heart; Hematologic Diseases; Humans; Kidney Failure, Chronic; Parathyroid Diseases; Parathyroid Hormone; Pharmaceutical Preparations; Rabbits; Rats; Thyroid Diseases; Uremia; Vasopressins; Vitamin D | 1974 |
10 trial(s) available for angiotensin ii and Aging
| Article | Year |
|---|---|
Oral Mg(2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Aged; Aging; Aldosterone; Angiotensin II; Arginine Vasopressin; Cross-Over Studies; Dietary Supplements; Drug Administration Schedule; Electroencephalography; Female; Hormones; Humans; Hydrocortisone; Magnesium Compounds; Male; Middle Aged; Renin; Sleep; Sleep Stages; Sleep Wake Disorders; Treatment Outcome | 2002 |
Vasoconstricting effect of angiotensin II in human hand veins: influence of aging, diabetes mellitus and hypertension.
Topics: Adult; Aged; Aging; Angiotensin II; Diabetes Mellitus, Type 2; Hand; Humans; Hypertension; Male; Middle Aged; Tachyphylaxis; Vasoconstriction; Vasoconstrictor Agents; Veins | 2002 |
The vascular impact of aging and vasoactive drugs: comparison of two digital volume pulse measurements.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Pressure; Blood Volume Determination; Fingers; Humans; Infusions, Intravenous; Male; Middle Aged; Nitroglycerin; Plethysmography; Reproducibility of Results; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
The effects of strength training on central arterial compliance in middle-aged and older adults.
Topics: Age Factors; Aging; Angiotensin II; Blood Pressure; Body Mass Index; Carotid Arteries; Cold Temperature; Compliance; Endothelin-1; Exercise; Female; Humans; Male; Manometry; Middle Aged; Muscle Strength; Muscle, Skeletal; Oxygen Consumption; Time Factors; Ultrasonography; Vasodilation | 2008 |
Angiotensin II in the elderly: impact of angiotensin II type 1 receptor sensitivity on peripheral hemodynamics.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Flow Velocity; Exercise; Humans; Hyperemia; Leg; Receptor, Angiotensin, Type 1; Regional Blood Flow; Rest; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Role of the renin-angiotensin system in hypertension in the elderly.
Topics: Adult; Aged; Aging; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Enalapril; Humans; Hypertension; Middle Aged; Prodrugs; Renin; Renin-Angiotensin System; Tetrazoles | 1994 |
Altered adrenal sensitivity to angiotensin II in low-renin essential hypertension.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Black People; Demography; Female; Humans; Hypertension; Male; Middle Aged; Renin; Vasoconstrictor Agents; White People | 1999 |
Increased vasoconstrictor sensitivity in obstructive sleep apnea.
Topics: Acetylcholine; Aging; Angiotensin II; Arterioles; Blood Flow Velocity; Blood Pressure; Body Mass Index; Forearm; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Regional Blood Flow; Sleep Apnea, Obstructive; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Blood pressure response to angiotensin II, low-density lipoprotein cholesterol and polymorphisms of the angiotensin II type 1 receptor gene in hypertensive sibling pairs.
Topics: Adult; Aging; Angiotensin II; Blood Pressure; Cholesterol, LDL; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle Aged; Nuclear Family; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sex Characteristics; White People | 2001 |
Effects of ketanserin on blood pressure and platelet aggregation in elderly men with mild hypertension.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Pressure; Calcium; Humans; Hypertension; Intracellular Membranes; Ketanserin; Male; Middle Aged; Osmolar Concentration; Phenylephrine; Platelet Aggregation | 1988 |
340 other study(ies) available for angiotensin ii and Aging
| Article | Year |
|---|---|
In Vivo Renin Activity Imaging in the Kidney of Progeroid
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; DNA Damage; DNA Repair; DNA-Binding Proteins; Endonucleases; Female; Gene Expression Regulation; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Losartan; Male; Mice; Mice, Knockout; Progeria; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Signal Transduction | 2021 |
Immature Vascular Smooth Muscle Cells in Healthy Murine Arteries and Atherosclerotic Plaques: Localization and Activity.
Topics: Aging; Angiotensin II; Animals; Aorta, Thoracic; Arteries; Carotid Artery, Common; Cell Movement; Cell Proliferation; Cells, Cultured; Immunophenotyping; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 2; Shear Strength; Stress, Mechanical | 2022 |
Angiotensin-(1-7), a protective peptide against vascular aging.
Topics: Aged; Aging; Angiotensin I; Angiotensin II; Frailty; Humans; Peptide Fragments; Renin-Angiotensin System | 2022 |
Regulator of G-Protein Signaling 5 Protein Deficiency Differentially Influences Blood Pressure, Vascular and Behavioral Effects in Aged Male Mice.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; GTP-Binding Proteins; Hypertension; Male; Mice; Protein Deficiency; RGS Proteins | 2022 |
Dysregulation of ACE-1 in Normal Aging and the Early Stages of Alzheimer's Disease.
Topics: Aging; Alzheimer Disease; Angiotensin II; Humans; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2022 |
Exerkine fibronectin type-III domain-containing protein 5/irisin-enriched extracellular vesicles delay vascular ageing by increasing SIRT6 stability.
Topics: Aged; Aging; Angiotensin II; Animals; Child, Preschool; Extracellular Vesicles; Fibronectins; HSP40 Heat-Shock Proteins; Humans; Inflammation; Mice; Mice, Knockout; Muscle, Skeletal; Sirtuins; Transcription Factors | 2022 |
Downregulation of P300/CBP-Associated Factor Protects from Vascular Aging via Nrf2 Signal Pathway Activation.
Topics: Aging; Angiotensin II; Animals; Down-Regulation; Endothelial Cells; Humans; Mice; NF-E2-Related Factor 2; p300-CBP Transcription Factors; Rats; RNA, Small Interfering; Signal Transduction | 2022 |
Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7).
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Claudin-1; Dysbiosis; Gastrointestinal Microbiome; Male; Mice; Occludin; Peptide Fragments; Peptidyl-Dipeptidase A | 2023 |
Expression and Function of Mas-Related G Protein-Coupled Receptor D and Its Ligand Alamandine in Retina.
Topics: Aging; Angiotensin II; Animals; Cells, Cultured; Electroretinography; Humans; Ligands; Lipopolysaccharides; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Rats; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Retina | 2020 |
Therapeutic Delivery of Ang(1-7) via Genetically Modified Probiotic: A Dosing Study.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Drug Administration Schedule; Lacticaseibacillus paracasei; Male; Models, Animal; Peptide Fragments; Pharmaceutical Vehicles; Probiotics; Proof of Concept Study; Rats; Rats, Inbred BN; Rats, Inbred F344; Recombinant Proteins | 2020 |
Aortic remodeling is modest and sex-independent in mice when hypertension is superimposed on aging.
Topics: Aging; Angiotensin II; Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Female; Hemodynamics; Hypertension; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Phenotype; Sodium Chloride, Dietary | 2020 |
Vascular Transcriptome Profiling Reveals Aging-Related Genes in Angiotensin Ⅱ-Induced Hypertensive Mouse Aortas.
Topics: Aging; Angiotensin II; Animals; Aorta; Blood Pressure; Gene Expression Profiling; Gene Ontology; Hypertension; Male; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction | 2020 |
Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency.
Topics: Aging; Angiotensin II; Animals; Glucuronidase; Hypertension; Klotho Proteins; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin-Light-Chain Phosphatase; Sodium Chloride, Dietary; Wnt-5a Protein | 2020 |
T cell aging in hypertension.
Topics: Aging; Angiotensin II; Cellular Senescence; Humans; Hypertension; T-Lymphocytes | 2021 |
The Protective Effect of Chlorogenic Acid on Vascular Senescence via the Nrf2/HO-1 Pathway.
Topics: Aging; Angiotensin II; Animals; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Chlorogenic Acid; Endothelial Cells; Female; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Oxidative Stress; Signal Transduction; Sirtuin 1 | 2020 |
Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation.
Topics: Aging; Angiotensin II; Animals; Arteries; Arteritis; Bone Marrow; Bone Marrow Transplantation; Cell Differentiation; Cell Lineage; Disease Models, Animal; Female; Hematopoietic Stem Cells; Homeostasis; Humans; Macrophages; Male; Mice; Mice, Transgenic; Regeneration; RNA-Seq; Single-Cell Analysis; Transplantation Chimera | 2020 |
Methylation-dependent antioxidant-redox imbalance regulates hypertensive kidney injury in aging.
Topics: Aging; Angiotensin II; Animals; Antioxidants; Hypertension; Kidney; Methylation; Mice; Mice, Inbred C57BL; NADPH Oxidases; Oxidation-Reduction; Oxidative Stress | 2020 |
Sirtuin 6 attenuates angiotensin II-induced vascular adventitial aging in rat aortae by suppressing the NF-κB pathway.
Topics: Aging; Angiotensin II; Animals; Aorta; Cardiovascular Physiological Phenomena; NF-kappa B; Rats; Sirtuins | 2021 |
In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism.
Topics: Age Factors; Aging; Angiotensin II; Animals; Blood Pressure; Body Weight; Endothelium, Vascular; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Hypertension; Mice; Receptor, Angiotensin, Type 2 | 2021 |
Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice.
Topics: Aging; Angiotensin II; Animals; Cerebral Hemorrhage; Hypertension; Matrix Metalloproteinase 9; Mice | 2021 |
miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling.
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiovascular Diseases; Endothelial Cells; Extracellular Matrix; Hypertension; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Nitric Oxide; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Vascular Stiffness | 2017 |
Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Diet; DNA Damage; DNA-Binding Proteins; Endonucleases; Female; Humans; Male; Mice; Mice, Knockout; Nitric Oxide; Receptor, Angiotensin, Type 1; Vascular Diseases; Vasodilation | 2017 |
Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress.
Topics: Aging; Angiotensin II; Animals; Biomarkers; Blood Pressure; Brain; Gene Expression Regulation; Inflammation; Kidney; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Oxidative Stress; Vasoconstriction | 2017 |
Glomerular and tubular effects of nitric oxide (NO) are regulated by angiotensin II (Ang II) in an age-dependent manner through activation of both angiotensin receptors (AT1Rs and AT2Rs) in conscious lambs.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; Male; Nephrons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Angiotensin; Sheep; Urodynamics; Wakefulness; Water-Electrolyte Balance | 2018 |
The intracellular angiotensin system buffers deleterious effects of the extracellular paracrine system.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cell Line; Cell Nucleus; Dopaminergic Neurons; Gene Expression Regulation; Humans; Hydrogen Peroxide; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Paracrine Communication; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Primary Cell Culture; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sirtuin 1; Substantia Nigra; Superoxides | 2017 |
Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation.
Topics: Aging; Angiotensin II; Animals; Aortic Valve Stenosis; Cells, Cultured; Chemokine CCL2; Fibroblasts; Fibrosis; Humans; Hypertension; Intercellular Adhesion Molecule-1; Intercellular Signaling Peptides and Proteins; Interleukin-1beta; Macrophages; Mice; Myocardium | 2018 |
Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Astrocytes; Case-Control Studies; Cell Nucleus; Cells, Cultured; Dopaminergic Neurons; Gene Deletion; Haplorhini; Male; Mesencephalon; Microglia; Mitochondria; Models, Biological; Neuroprotection; Oxidative Stress; Paracrine Communication; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Nitrogen Species; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Rodentia; Signal Transduction; Substantia Nigra | 2018 |
[Effects of electroacupuncture on postoperative cognitive dysfunction and AngⅡ/AT1R in the hippocampus in aging rats induced by D-galactose].
Topics: Acupuncture Points; Aging; Angiotensin II; Animals; Cognitive Dysfunction; Electroacupuncture; Galactose; Hepatectomy; Hippocampus; Male; Postoperative Complications; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2017 |
Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Angiotensin II; Aspartic Acid Endopeptidases; Blotting, Western; Brain; Cerebral Amyloid Angiopathy; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Vasoconstrictor Agents | 2018 |
IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
Topics: Aging; Angiotensin II; Animals; Cerebral Arteries; Cerebral Hemorrhage; Disease Models, Animal; Hypertension; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL | 2019 |
Serum containing Buyang Huanwu decoction prevents age-associated migration and invasion of human vascular smooth muscle cells by up regulating SIRT1 expression.
Topics: Aging; Angiotensin II; Aorta; Cardiovascular Diseases; Cell Movement; Cell Proliferation; Cells, Cultured; Cellular Senescence; Down-Regulation; Drugs, Chinese Herbal; Gene Knockdown Techniques; Humans; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Up-Regulation | 2018 |
Hypertension exaggerates renovascular resistance via miR-122-associated stress response in aging.
Topics: Aging; Angiotensin II; Animals; Basic-Leucine Zipper Transcription Factors; Blood Pressure; Chemokine CCL2; Collagen; Down-Regulation; Heme Oxygenase-1; Histones; Hypertension; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; MicroRNAs; Vascular Resistance | 2018 |
Angiotensin II- and Alzheimer-Type Cardiovascular Aging.
Topics: Age Factors; Aging; Alzheimer Disease; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Autophagy; Brain; Cardiovascular Diseases; Cardiovascular System; Cellular Senescence; Humans; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Unfolded Protein Response | 2018 |
Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction.
Topics: Aging; Angiotensin II; Animals; Antigens, Differentiation; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Calcium-Binding Proteins; Cognitive Dysfunction; Disease Models, Animal; Genes, MHC Class II; Hippocampus; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia | 2019 |
Angiotensin II-induced redox-sensitive SGLT1 and 2 expression promotes high glucose-induced endothelial cell senescence.
Topics: Aging; Angiotensin II; Animals; Benzhydryl Compounds; Cells, Cultured; Cellular Senescence; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Glucose; Glucosides; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxidative Stress; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Swine | 2020 |
Angiotensin II-mediated vascular changes in aged offspring rats exposed to perinatal nicotine.
Topics: Acetylcholine; Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Abdominal; Blood Pressure; Female; In Vitro Techniques; Losartan; Male; Maternal-Fetal Exchange; Mesenteric Arteries; Muscle, Smooth, Vascular; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilation; Vasodilator Agents | 2013 |
Deficiency of senescence marker protein 30 exacerbates angiotensin II-induced cardiac remodelling.
Topics: Aging; Angiotensin II; Animals; Apoptosis; Ascorbic Acid; bcl-2-Associated X Protein; Biomarkers; Calcium-Binding Proteins; Cardiomegaly; Caspase 3; Disease Models, Animal; Fibrosis; Heart Failure; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Ventricular Remodeling | 2013 |
Expression of angiotensin II and its receptors in activated microglia in experimentally induced cerebral ischemia in the adult rats.
Topics: Aging; Angiotensin II; Animals; Antipyrine; Blotting, Western; Brain Ischemia; Cerebral Cortex; Edaravone; Gene Expression Regulation; Interleukin-1beta; Male; Microglia; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tumor Necrosis Factor-alpha | 2013 |
Long-term effects of early overnutrition in the heart of male adult rats: role of the renin-angiotensin system.
Topics: Aging; Angiotensin II; Animals; Apoptosis; Biomarkers; Bradykinin; Feeding Behavior; Gene Expression Regulation; Heart; Hemodynamics; In Vitro Techniques; Inflammation; Leptin; Male; Myocardium; Organ Size; Overnutrition; Perfusion; Rats, Sprague-Dawley; Renin-Angiotensin System; Time Factors; Vasoconstriction; Vasodilation | 2014 |
Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
Topics: Actins; Adaptation, Physiological; Aging; Angiotensin II; Animals; Behavior, Animal; Blood-Brain Barrier; Cerebrovascular Circulation; Cytokines; Disease Models, Animal; Hydroxyeicosatetraenoic Acids; Hypertension; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microvessels; Middle Cerebral Artery; TRPC Cation Channels; TRPC6 Cation Channel; Up-Regulation | 2013 |
Collagenase-resistant collagen promotes mouse aging and vascular cell senescence.
Topics: Aging; Angiotensin II; Animals; Aorta; Cellular Senescence; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagenases; Embryo, Mammalian; Fibroblasts; Humans; Hypertension; Integrin alphaVbeta3; Longevity; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Phenotype; Proteolysis; Stress, Physiological | 2014 |
Age determines the magnitudes of angiotensin II-induced contractions, mRNA, and protein expression of angiotensin type 1 receptors in rat carotid arteries.
Topics: Aging; Angiotensin II; Animals; Carotid Arteries; Male; Myography; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents | 2014 |
Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice.
Topics: Aging; Angiotensin II; Animals; Calcium; Calcium Signaling; Hydroxyeicosatetraenoic Acids; Hypertension; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Mice; Mice, Inbred C57BL; Middle Cerebral Artery; Muscle Contraction; Muscle, Smooth, Vascular; TRPC Cation Channels; Vasoconstriction | 2013 |
COX2 inhibition during nephrogenic period induces ANG II hypertension and sex-dependent changes in renal function during aging.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Female; Glomerular Filtration Rate; Hypertension; Kidney; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2014 |
Attenuation of L-type Ca²⁺ channel expression and vasomotor response in the aorta with age in both Wistar-Kyoto and spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Angiotensin II; Animals; Aorta, Thoracic; Calcium Channel Blockers; Calcium Channels, L-Type; Gene Expression Regulation; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction; Vasodilation | 2014 |
Valsartan ameliorates ageing-induced aorta degeneration via angiotensin II type 1 receptor-mediated ERK activity.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blotting, Western; Cells, Cultured; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Immunoenzyme Techniques; Male; Phosphorylation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Valine; Valsartan | 2014 |
Ageing-related cardiomyocyte functional decline is sex and angiotensin II dependent.
Topics: Aging; Angiotensin II; Animals; Female; Gene Expression Regulation, Developmental; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2014 |
Endothelin-1 but not angiotensin II contributes to functional aging in murine carotid arteries.
Topics: Aging; Angiotensin II; Animals; Area Under Curve; Carotid Artery, Common; Endothelin-1; Gene Expression Regulation; In Vitro Techniques; Male; Mice, Inbred C57BL; NADPH Oxidases; Receptors, Endothelin; Receptors, Thromboxane; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2014 |
Slow-pressor angiotensin II hypertension and concomitant dendritic NMDA receptor trafficking in estrogen receptor β-containing neurons of the mouse hypothalamic paraventricular nucleus are sex and age dependent.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Dendrites; Estrogen Receptor beta; Estrous Cycle; Female; Green Fluorescent Proteins; Male; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Paraventricular Hypothalamic Nucleus; Receptors, N-Methyl-D-Aspartate; Sex Factors; Stilbamidines; Time Factors | 2014 |
ADAMTS-7 expression increases in the early stage of angiotensin II-induced renal injury in elderly mice.
Topics: ADAM Proteins; ADAMTS7 Protein; Aging; Angiotensin II; Animals; Blood Pressure; HEK293 Cells; Humans; Inflammation; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Vasoconstrictor Agents | 2013 |
From autophagy to senescence and apoptosis in Angiotensin II-treated vascular endothelial cells.
Topics: Aging; Angiotensin II; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cells, Cultured; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Membrane Proteins; Proto-Oncogene Proteins c-bcl-2 | 2014 |
Aliskiren-attenuated myocardium apoptosis via regulation of autophagy and connexin-43 in aged spontaneously hypertensive rats.
Topics: Aging; Amides; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Blood Pressure; Blotting, Western; Cell Proliferation; Cells, Cultured; Connexin 43; Fluorescent Antibody Technique; Fumarates; Immunoenzyme Techniques; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2014 |
Angiotensin II and 1-7 during aging in Metabolic Syndrome rats. Expression of AT1, AT2 and Mas receptors in abdominal white adipose tissue.
Topics: Adipose Tissue, White; Aging; Angiotensin I; Angiotensin II; Animals; Gene Expression Regulation; Humans; Hypertension; Metabolic Syndrome; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2014 |
[Exogenous hydrogen sulfide reduces vascular aging in D-galactose-induced subacute aging rats].
Topics: Aging; Angiotensin II; Animals; Aorta; Cell Proliferation; Endothelial Cells; Galactose; Hydrogen Sulfide; Male; Malondialdehyde; Myocytes, Smooth Muscle; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sulfides; Superoxide Dismutase | 2014 |
Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent.
Topics: Aging; Angiotensin II; Animals; Biomarkers; Cell Adhesion Molecules; Cellular Senescence; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Interleukin-13; Interleukin-4; Interleukin-6; Mitogen-Activated Protein Kinase Kinases; Myocardium; Myocytes, Cardiac; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Signal Transduction; Transforming Growth Factor beta1 | 2014 |
IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
Topics: Aging; Angiotensin II; Animals; Biomarkers; Blood-Brain Barrier; Cerebrovascular Circulation; Dementia; Disease Models, Animal; Encephalitis; Hippocampus; Homeostasis; Hypertension; Insulin-Like Growth Factor I; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Microglia; Middle Cerebral Artery; TRPC Cation Channels; Vasoconstrictor Agents | 2014 |
Impaired myocardial development resulting in neonatal cardiac hypoplasia alters postnatal growth and stress response in the heart.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Embryonic Development; Female; Fetal Development; Heart; Hypertrophy; Lyases; Mice; Mice, Knockout; Models, Animal; Myocytes, Cardiac; Organ Size; STAT3 Transcription Factor; Stress, Physiological | 2015 |
CREG1 ameliorates myocardial fibrosis associated with autophagy activation and Rab7 expression.
Topics: Aging; Angiotensin II; Animals; Autophagy; Cells, Cultured; Disease Susceptibility; Fibrosis; Lysosomes; Male; Mice; Myocardium; Myocytes, Cardiac; Phagosomes; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Recombinant Proteins; Repressor Proteins | 2015 |
Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses.
Topics: Adipose Tissue; Aging; Angiotensin II; Animals; Body Composition; CD4-Positive T-Lymphocytes; Cytokines; Female; Glucose Intolerance; Inflammation; Insulin; Insulin Resistance; Islets of Langerhans; Male; Membrane Glycoproteins; Metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Receptor, Adenosine A1; Regional Blood Flow; Signal Transduction | 2015 |
'Fine-tuning' blood flow to the exercising muscle with advancing age: an update.
Topics: Adaptation, Physiological; Age Factors; Aging; Angiotensin II; Endothelin-1; Endothelium, Vascular; Exercise; Humans; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitric Oxide; Receptors, Adrenergic, alpha; Regional Blood Flow; Signal Transduction; Sympathetic Nervous System | 2015 |
Poly(ADP-ribose)polymerase 1 inhibition protects against age-dependent endothelial dysfunction.
Topics: Active Transport, Cell Nucleus; Aging; Angiotensin II; Animals; Cell Nucleus; Endothelium, Vascular; Gene Deletion; Gene Expression Regulation, Enzymologic; Humans; Male; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitriles; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-akt; Sulfones; Superoxides | 2015 |
Reciprocal regulation between sirtuin-1 and angiotensin-II in the substantia nigra: implications for aging and neurodegeneration.
Topics: Aging; Angiotensin II; Animals; Brain; Cell Line; Dopaminergic Neurons; Gene Expression Regulation; Homozygote; Humans; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Fluorescence; NADPH Oxidases; Neurodegenerative Diseases; Neuroglia; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Resveratrol; Sirtuin 1; Stilbenes; Substantia Nigra | 2015 |
Molecular and cellular mechanisms of glucagon-like peptide-1 receptor agonist-mediated attenuation of cardiac fibrosis.
Topics: Aging; Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Chemokine CCL2; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Fibrosis; Glucagon-Like Peptide-1 Receptor; Heart; Heart Diseases; Hypertension; I-kappa B Proteins; Immunohistochemistry; Incretins; Inflammation; Interleukin-10; Liraglutide; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocardium; NF-kappa B p50 Subunit; Obesity; Oxidative Stress; Real-Time Polymerase Chain Reaction; Vasoconstrictor Agents; Vimentin | 2016 |
The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4.
Topics: Aging; Angiotensin II; Animals; Cell Movement; Cell Proliferation; Enzyme Activation; Fibroblasts; Gene Knockdown Techniques; Humans; Interleukin-18; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Myocardium; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Oxidative Stress; Protein Binding; Pyrazoles; Pyrazolones; Pyridines; Pyridones; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Transcription Factor AP-1 | 2016 |
Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II-induced hypertension.
Topics: Aging; Angiotensin II; Animals; HEK293 Cells; Humans; Hypertension; Mice; Mice, Knockout; Protein Multimerization; Receptor, Angiotensin, Type 1; Receptors, Purinergic P2 | 2016 |
[Intervention Mechanism of Extracts from Radix Ginseng, Radix Notoginseng and Rhizoma Chuanxiong on Adventitia of Senescent Rats].
Topics: Adventitia; Aging; Angiotensin II; Animals; Aorta, Thoracic; Drugs, Chinese Herbal; Losartan; Panax; Plant Roots; Rats; Rats, Wistar; Renin-Angiotensin System; Rhizome; RNA, Messenger | 2015 |
Short-duration increases in intraluminal pressure improve vasoconstrictor responses in aged skeletal muscle feed arteries.
Topics: Aging; Amides; Angiotensin II; Animals; Arteries; Endothelium, Vascular; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Physical Conditioning, Animal; Pressure; Pyridines; Rats; Rats, Inbred F344; rho-Associated Kinases; Vasoconstriction; Vasoconstrictor Agents | 2016 |
Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging.
Topics: 1-Methyl-4-phenylpyridinium; Age Factors; Aging; Angiotensin II; Animals; Apoptosis; Cells, Cultured; Dopaminergic Neurons; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Inflammation; Injections, Intraventricular; Insulin-Like Growth Factor I; Microglia; Neurodegenerative Diseases; Oxidative Stress; Primary Cell Culture; Rats; Receptor, Angiotensin, Type 1; Receptor, IGF Type 1; Renin-Angiotensin System; Substantia Nigra | 2016 |
Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Blotting, Western; Collagen Type IV; Deoxyguanosine; Enzyme-Linked Immunosorbent Assay; Fibronectins; Immunohistochemistry; Mice, Inbred C57BL; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Superoxide Dismutase; Transforming Growth Factor beta; Tyrosine | 2016 |
Healthy ageing of cloned sheep.
Topics: Adiposity; Aging; Angiotensin II; Animals; Blood Pressure; Body Composition; Cloning, Organism; Embryo Transfer; Glucose Tolerance Test; Heart Rate; Insulin Resistance; Joints; Magnetic Resonance Imaging; Sheep; Systole | 2016 |
Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells.
Topics: Aging; Angiotensin II; Animals; Aorta; Cells, Cultured; Muscle, Smooth, Vascular; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Rubus; Signal Transduction | 2016 |
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
Topics: Aging; Alzheimer Disease; Angiotensin II; Animals; Biomarkers; Blood-Brain Barrier; Cognitive Dysfunction; Gene Expression; Hippocampus; Humans; Hypertension; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Microvascular Rarefaction; Neocortex; RNA, Messenger | 2016 |
Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm.
Topics: Aging; Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Aortitis; Apolipoproteins E; Calcium Chloride; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; NF-kappa B; Sirtuin 1 | 2016 |
The anti-ageing hormone klotho induces Nrf2-mediated antioxidant defences in human aortic smooth muscle cells.
Topics: Aging; Angiotensin II; Antioxidants; Aorta; Apoptosis; Cells, Cultured; Glucuronidase; Glutathione; Heme Oxygenase-1; Humans; Klotho Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Signal Transduction | 2017 |
Sex differences in angiotensin II responses contribute to a differential regulation of cox-mediated vascular dysfunction during aging.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase 2; Endothelium, Vascular; Female; Indomethacin; Losartan; Male; Mice; Oxidative Stress; Prostaglandins; Renin-Angiotensin System; Sex Factors; Vasodilation | 2016 |
Chymase-dependent production of angiotensin II: an old enzyme in old hearts.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Chymases; Enzyme-Linked Immunosorbent Assay; Myocardium; NADPH Oxidases; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Superoxides | 2017 |
Transcription factor PEX1 modulates extracellular matrix turnover through regulation of MMP-9 expression.
Topics: Adenoviridae; Aging; Angiotensin II; Animals; Animals, Newborn; Base Sequence; Extracellular Matrix; Fibroblasts; Fibrosis; Gene Expression Regulation; Gene Silencing; Gene Transfer Techniques; Hypertension; Matrix Metalloproteinase 9; Membrane Proteins; Models, Biological; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Promoter Regions, Genetic; Rats, Sprague-Dawley; Transcription Factors | 2017 |
Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.
Topics: Aging; Angiotensin II; Animals; Cerebral Hemorrhage; Disease Models, Animal; Extracellular Matrix; Gait; Hypertension; Infusion Pumps, Implantable; Insulin-Like Growth Factor I; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Oxidative Stress; Phenotype; Psychomotor Performance | 2017 |
Effect of age on angiotensin II-mediated downregulation of adrenomedullary catecholamine biosynthetic enzymes.
Topics: Adrenal Medulla; Aging; Angiotensin II; Animals; Dopamine beta-Hydroxylase; Down-Regulation; Gene Expression Regulation, Enzymologic; Male; Neuropeptide Y; Rats; Rats, Inbred F344; RNA, Messenger; Tyrosine 3-Monooxygenase | 2008 |
Bibliography. Current world literature. Hypertension.
Topics: Adrenergic beta-Antagonists; Aging; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Cannabinoid Receptor Modulators; Diabetes Complications; Endothelin-1; Genetic Therapy; Heart; Humans; Hypertension; Peptidyl-Dipeptidase A; Pharmacogenetics; Social Class; Sodium Chloride, Dietary; Stress, Physiological | 2008 |
Angiotensin II induces apoptosis in human mural granulosa-lutein cells, but not in cumulus cells.
Topics: Adolescent; Adult; Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Apoptosis; Cell Culture Techniques; Culture Media, Serum-Free; Cumulus Cells; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Granulosa Cells; Humans; Menstrual Cycle; Ovulation Induction; Patient Selection; Receptor, Angiotensin, Type 1; Young Adult | 2009 |
[The study on inhabiting endothelial cell aging by targeted silencing of p22phox].
Topics: Aging; Angiotensin II; Blotting, Western; Cells, Cultured; Cellular Senescence; Endothelial Cells; Gene Expression; Humans; NADPH Oxidases; Nitric Oxide; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering | 2008 |
Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Blotting, Western; Bradykinin; Gene Expression Regulation; Imidazoles; Losartan; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Vasodilation | 2009 |
Long-term angiotensin II blockade may improve not only hyperglycemia but also age-associated cardiac fibrosis.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fibrosis; Heart Failure; Hyperglycemia; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Tetrazoles | 2009 |
Cardiovascular and autonomic phenotype of db/db diabetic mice.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Cardiovascular System; Circadian Rhythm; Diabetes Complications; Diabetes Mellitus, Type 2; Disease Models, Animal; Heart Rate; Hypertension; Losartan; Male; Mice; Mice, Mutant Strains; Motor Activity; Peptidyl-Dipeptidase A; Phenotype; Receptor, Angiotensin, Type 1; Receptors, Leptin | 2009 |
Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Basilar Artery; Calcimycin; Cerebrovascular Circulation; Ionophores; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 2009 |
Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion.
Topics: Adolescent; Adult; Aged; Aging; Angiotensin II; Animals; Antigens, Surface; Aorta; Atherosclerosis; Cell Movement; Chemokine CCL2; Gene Expression Regulation; Gene Silencing; Humans; Macaca mulatta; Male; Middle Aged; Milk Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred F344; Receptors, CCR2; Signal Transduction; Vasoconstrictor Agents; Viral Proteins; Virulence Factors | 2009 |
Gene knockout of insulin-regulated aminopeptidase: loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory.
Topics: Aging; Angiotensin II; Animals; Brain; Cystinyl Aminopeptidase; Glucose Transporter Type 4; Male; Maze Learning; Memory Disorders; Mice; Mice, Knockout; Neuropsychological Tests; Phenotype; Receptors, Angiotensin; Recognition, Psychology; Space Perception | 2010 |
Age-dependent differential crosstalk between alpha(1)-adrenergic and angiotensin receptors.
Topics: Age Factors; Aging; Angiotensin II; Animals; Male; Myocardial Contraction; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, alpha-1; Renin-Angiotensin System; Signal Transduction; Sympathetic Nervous System | 2009 |
Sex and age result in differential regulation of the renal thiazide-sensitive NaCl cotransporter and the epithelial sodium channel in angiotensin II-infused mice.
Topics: Age Factors; Aging; Angiotensin II; Animals; Blood Pressure; Diuretics; Epithelial Sodium Channels; Female; Hydrochlorothiazide; Hypertension, Renal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Natriuresis; Receptors, Drug; Sex Characteristics; Sex Factors; Solute Carrier Family 12, Member 3; Symporters; Vasoconstrictor Agents | 2009 |
Sex differences in adaptive downregulation of pre-macula densa sodium transporters with ANG II infusion in mice.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Down-Regulation; Female; Kidney Tubules, Proximal; Loop of Henle; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Models, Animal; Sex Characteristics; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sodium-Phosphate Cotransporter Proteins, Type II; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Solute Carrier Family 12, Member 1; Vasoconstrictor Agents | 2010 |
Hemodynamic alterations in the coronary circulation of cardiomyopathic hamsters: age and Ang II-dependent mechanisms.
Topics: Aging; Angiotensin II; Animals; Cardiomyopathies; Coronary Circulation; Cricetinae; Heart Rate; Hemodynamics; Male; Mesocricetus | 2009 |
Involvement of NADPH oxidase in age-associated cardiac remodeling.
Topics: Aging; Angiotensin II; Animals; Crosses, Genetic; Cytokines; In Situ Hybridization; Male; NADPH Oxidases; Oxidative Stress; Platelet Endothelial Cell Adhesion Molecule-1; Protein Isoforms; Rats; Rats, Inbred F344; Time Factors; Ventricular Remodeling | 2010 |
Aldosterone production and insulin resistance in healthy adults.
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Angiotensin II; Blood Pressure; Body Mass Index; Female; Humans; Insulin Resistance; Male; Middle Aged; Predictive Value of Tests; Reference Values; Sex Characteristics; Stimulation, Chemical; Young Adult | 2010 |
Hypertensive effects of central angiotensin II infusion and restraint stress are reduced with age.
Topics: Aging; Angiotensin II; Animals; Base Sequence; Blood Pressure; DNA Primers; Electron Spin Resonance Spectroscopy; Heart Rate; Hypertension; Immobilization; Locomotion; Male; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological | 2010 |
Age is a determinant of acute hemodynamic responses to hyperglycemia and angiotensin II in humans with uncomplicated type 1 diabetes mellitus.
Topics: Adolescent; Adult; Aging; Angiotensin II; Blood Pressure; Diabetes Mellitus, Type 1; Female; Glomerular Filtration Rate; Glucose Clamp Technique; Hemodynamics; Humans; Hyperglycemia; Kidney; Male; Polyuria; Renal Plasma Flow, Effective; Renin-Angiotensin System; Thirst; Vascular Resistance | 2010 |
Memory may not be the first thing to go: focus on "Drinking and arterial blood pressure responses to ANG II in young and old rats".
Topics: Adaptation, Physiological; Age Factors; Aging; Angiotensin II; Animals; Baroreflex; Behavior, Animal; Blood Pressure; Drinking; Drinking Behavior; Humans; Infusions, Intravenous; Memory; Rats; Urodynamics; Vasodilator Agents; Water-Electrolyte Balance | 2010 |
Drinking and arterial blood pressure responses to ANG II in young and old rats.
Topics: Adaptation, Physiological; Age Factors; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Behavior, Animal; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Heart Rate; Infusions, Intravenous; Male; Minoxidil; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Urodynamics; Vasodilator Agents; Water-Electrolyte Balance | 2010 |
The renin-angiotensin system and hypertension in autosomal recessive polycystic kidney disease.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Hypertension; Kidney; Male; Mutation; Peptidyl-Dipeptidase A; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Time Factors | 2010 |
Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Angiotensin II; Animals; Blotting, Western; Chronic Disease; Cyclosporine; Deoxyguanosine; Disease Models, Animal; Glucuronidase; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Diseases; Klotho Proteins; Male; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Vasoconstrictor Agents | 2011 |
Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy.
Topics: Age Factors; Aging; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomyopathies; Collagen; Coronary Circulation; Disease Models, Animal; Echocardiography; Elasticity; Enzyme Inhibitors; Extracellular Matrix; Female; Gene Expression Profiling; Gene Expression Regulation; Genotype; Heart Ventricles; Hemodynamics; Hypertension; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Microscopy, Electron; Microscopy, Video; Myocardium; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenotype; Polymerase Chain Reaction; RNA, Messenger; Telemetry; Ventricular Remodeling | 2010 |
Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Dopaminergic Neurons; Inflammation Mediators; Interleukin-1beta; Male; Molecular Targeted Therapy; NADPH Oxidases; Nerve Degeneration; Oxidative Stress; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Substantia Nigra; Tetrazoles; Tumor Necrosis Factor-alpha | 2012 |
The frail renin-angiotensin system.
Topics: Aged; Aging; Angiotensin II; Apoptosis; Disease Progression; Frail Elderly; Humans; Hypertension; Inflammation; Oxidative Stress; Reactive Oxygen Species; Receptors, Angiotensin; Renin-Angiotensin System | 2011 |
Chronic intake of red wine polyphenols by young rats prevents aging-induced endothelial dysfunction and decline in physical performance: role of NADPH oxidase.
Topics: Acetophenones; Aging; Angiotensin II; Animals; Antioxidants; Arginase; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Motor Activity; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phenols; Polyphenols; Rats; Reactive Oxygen Species; Wine | 2011 |
Mechanism of Ang II involvement in activation of NF-κB through phosphorylation of p65 during aging.
Topics: Aging; Angiotensin II; Animals; Cell Line; Endothelial Cells; Models, Animal; NF-kappa B; Phosphorylation; Rats; Rats, Inbred F344; Signal Transduction; Transcription Factor RelA | 2012 |
Inhibition of NF-κB-induced inflammatory responses by angiotensin II antagonists in aged rat kidney.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Gene Expression; Kidney; Losartan; Male; MAP Kinase Signaling System; Nephritis; NF-kappa B; Oxidative Stress; Phosphorylation; Random Allocation; Rats; Rats, Inbred BN; Rats, Inbred F344; Transcription Factor RelA | 2011 |
Reduced proliferation of aged human vascular smooth muscle cells--role of oxygen-derived free radicals and BubR1 expression.
Topics: Adolescent; Adult; Aging; Angiotensin II; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Free Radicals; Gene Expression Regulation; Humans; Hydrogen Peroxide; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Serine-Threonine Kinases; Reactive Oxygen Species; RNA, Messenger | 2011 |
Long-term exercise attenuates blood pressure responsiveness and modulates kidney angiotensin II signalling and urinary sodium excretion in SHR.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Body Weight; Creatinine; Kidney; Kidney Function Tests; Male; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction; Sodium; Systole; Time Factors | 2011 |
Mitochondrial ATP-sensitive potassium channels enhance angiotensin-induced oxidative damage and dopaminergic neuron degeneration. Relevance for aging-associated susceptibility to Parkinson's disease.
Topics: Aging; Angiotensin II; Animals; Cells, Cultured; Dopaminergic Neurons; Fluorescence; Humans; Immunohistochemistry; Male; Oxidative Stress; Oxidopamine; Parkinson Disease; Potassium Channels; Rats; Reactive Oxygen Species; Reference Values; Renin-Angiotensin System; Sensitivity and Specificity; Substantia Nigra | 2012 |
Mechanism of attenuation of pro-inflammatory Ang II-induced NF-κB activation by genistein in the kidneys of male rats during aging.
Topics: Age Factors; Aging; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation; Genistein; Inflammation Mediators; Kidney; Male; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2011 |
ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autonomic Nervous System; Blood Pressure; Brain; Cell Line, Tumor; Central Nervous System; Gene Deletion; Genetic Therapy; Male; Mice; Myocardium; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; Primary Dysautonomias; Reactive Oxygen Species; Sympathetic Nervous System; Vagus Nerve | 2011 |
MicroRNA-29 in aortic dilation: implications for aneurysm formation.
Topics: Aging; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Biopsy; Dilatation, Pathologic; Disease Models, Animal; Extracellular Matrix Proteins; Gene Expression Profiling; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; MicroRNAs; Mutation; Oligoribonucleotides, Antisense | 2011 |
Effects of intra- and extracellular factors on anti-aging klotho gene expression.
Topics: Aging; Angiotensin II; Apoptosis; Calcium; Cell Line; Cyclin-Dependent Kinase Inhibitor p16; Gene Expression Regulation; Genes, Reporter; Glucuronidase; Green Fluorescent Proteins; HEK293 Cells; Humans; Insulin-Like Growth Factor I; Klotho Proteins; Luciferases; Neoplasm Proteins; Parathyroid Hormone; Phosphates; rho GTP-Binding Proteins; Sequence Deletion; Tumor Suppressor Protein p53 | 2011 |
Angiotensin II receptor activation in youth triggers persistent insulin resistance and hypertension--a legacy effect?
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Body Weight; Chemokine CCL2; Disease Models, Animal; Hypertension; Insulin Resistance; Muscle, Skeletal; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Angiotensin; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2012 |
Haemodynamic responses to angiotensin II in conscious lambs: role of nitric oxide and prostaglandins.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Cyclooxygenase Inhibitors; Female; Hemodynamics; Indomethacin; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Renal Circulation; Sheep, Domestic; Vasoconstriction | 2012 |
'Memory' and 'legacy' in hypertension and lifestyle-related diseases.
Topics: Aging; Angiotensin II; Animals; Hypertension; Insulin Resistance; Receptors, Angiotensin | 2012 |
Enhanced sensitivity of aged fibrotic hearts to angiotensin II- and hypokalemia-induced early afterdepolarization-mediated ventricular arrhythmias.
Topics: Aging; Angiotensin II; Animals; Arrhythmias, Cardiac; Disease Models, Animal; Fibrosis; Heart; Hypokalemia; Male; Myocardium; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; Patch-Clamp Techniques; Rats; Rats, Inbred F344; Reactive Oxygen Species; Ventricular Fibrillation | 2012 |
Thymoquinone improves aging-related endothelial dysfunction in the rat mesenteric artery.
Topics: Aging; Angiotensin II; Animals; Benzoquinones; Biological Factors; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peptidyl-Dipeptidase A; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Vasodilation | 2012 |
Involvement of the skeletal renin-angiotensin system in age-related osteoporosis of ageing mice.
Topics: Aging; Angiotensin II; Animals; Bone Density; Femur; Gene Expression Regulation; Histocytochemistry; Humans; Male; Mice; Mice, Inbred ICR; Osteoporosis; Renin; Renin-Angiotensin System; Tibia; Tomography, X-Ray Computed | 2012 |
Effects of aging, TNF-α, and exercise training on angiotensin II-induced vasoconstriction of rat skeletal muscle arterioles.
Topics: Aging; Angiotensin II; Animals; Arterioles; Education; Endothelium, Vascular; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction | 2012 |
Perinatal Na+ overload programs raised renal proximal Na+ transport and enalapril-sensitive alterations of Ang II signaling pathways during adulthood.
Topics: Adenosine Triphosphatases; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Blood Pressure; Body Weight; Cation Transport Proteins; Creatinine; Cyclic AMP-Dependent Protein Kinases; Enalapril; Female; Gene Expression Regulation; Kidney Tubules, Proximal; Lipid Peroxidation; Macrophages; Male; Parturition; Pregnancy; Protein Kinase C; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Water; Weaning | 2012 |
Early changes of hypothalamic angiotensin II receptors expression in gestational protein-restricted offspring: effect on water intake, blood pressure and renal sodium handling.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Creatinine; Drinking; Female; Hypothalamus; Kidney; Kidney Function Tests; Lithium; Male; Osmolar Concentration; Potassium; Pregnancy; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium; Vasopressins | 2013 |
Angiotensin II potentiates α-adrenergic vasoconstriction in the elderly.
Topics: Adult; Aged; Aging; Angiotensin II; Drug Synergism; Humans; Norepinephrine; Phentolamine; Receptors, Adrenergic, alpha; Renin-Angiotensin System; Vasoconstriction | 2013 |
Captopril avoids hypertension, the increase in plasma angiotensin II but increases angiotensin 1-7 and angiotensin II-induced perfusion pressure in isolated kidney in SHR.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Peptide Fragments; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Specific Pathogen-Free Organisms; Vascular Resistance | 2012 |
Role of angiotensin II in arterial pressure and renal hemodynamics in rats with altered renal development: age- and sex-dependent differences.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arterial Pressure; Benzimidazoles; Biphenyl Compounds; Female; Kidney; Male; Mesenteric Arteries; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sex Characteristics; Tetrazoles | 2013 |
Aged rats are susceptible to nephrotoxicity induced by iodinated contrast media.
Topics: Aging; Angiotensin II; Animals; Contrast Media; Diatrizoate Meglumine; Disease Models, Animal; Kidney; Kidney Diseases; Male; Malondialdehyde; NADP; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Superoxide Dismutase | 2013 |
Impact of ACE2 deficiency and oxidative stress on cerebrovascular function with aging.
Topics: Acetylcholine; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Male; Mice; Mice, Knockout; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger; Vasculitis; Vasodilation; Vasodilator Agents | 2012 |
Early life stress induces renal dysfunction in adult male rats but not female rats.
Topics: Age Factors; Aging; Angiotensin II; Animals; Anxiety, Separation; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Creatinine; Disease Models, Animal; Estradiol; Female; Hypertension; Kidney; Kidney Diseases; Male; Maternal Deprivation; Orchiectomy; Proteinuria; Rats; Rats, Inbred WKY; Sex Factors; Stress, Psychological; Telemetry; Testosterone | 2013 |
Reductions in water and sodium intake by aged male and female rats.
Topics: Age Factors; Aging; Angiotensin II; Animals; Atrial Natriuretic Factor; Drinking; Female; Hot Temperature; Hypothalamus; Male; Rats; Rats, Inbred Strains; Receptor, Angiotensin, Type 1; RNA, Messenger; Sex Factors; Sodium; Sodium Chloride; Sodium Chloride, Dietary; Thirst; Water; Water Deprivation | 2012 |
Roles played by 20-HETE, angiotensin II and endothelin in mediating the hypertension in aging female spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Endothelins; Female; Hydroxyeicosatetraenoic Acids; Hypertension; Rats; Rats, Inbred SHR | 2013 |
Differential involvement of protein kinase C in basal versus acetylcholine-regulated prolactin secretion in rat anterior pituitary cells during aging.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Dopamine; Female; Pituitary Gland, Anterior; Prolactin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 2002 |
Differential response of cardiac fibroblasts from young adult and senescent rats to ANG II.
Topics: Aging; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Collagen; Fibroblasts; Gene Expression Regulation; Male; Myocardium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta | 2003 |
Depressor effect induced by dipeptide, Val-Tyr, in hypertensive transgenic mice is due, in part, to the suppression of human circulating renin-angiotensin system.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dipeptides; Humans; Hypertension; Male; Mice; Mice, Transgenic; Renin-Angiotensin System | 2003 |
Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates.
Topics: Aging; Angiotensin II; Animals; Aorta; Chymases; Enzyme Activation; In Situ Hybridization; Macaca fascicularis; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Peptidyl-Dipeptidase A; RNA, Messenger; Serine Endopeptidases; Tissue Inhibitor of Metalloproteinase-2 | 2003 |
Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat.
Topics: Aging; Angiotensin II; Animals; Down-Regulation; Free Radical Scavengers; Gene Expression Regulation; Glucuronidase; Iron Chelating Agents; Iron Overload; Kidney; Klotho Proteins; Male; Membrane Proteins; Oxidative Stress; Phenylurea Compounds; Proteinuria; Pyridines; Rats; Rats, Sprague-Dawley | 2003 |
Rat aortic MCP-1 and its receptor CCR2 increase with age and alter vascular smooth muscle cell function.
Topics: Aging; Angiotensin II; Animals; Aorta; Cell Division; Cell Movement; Cells, Cultured; Chemokine CCL2; Chemotaxis; Crosses, Genetic; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation, Developmental; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred BN; Rats, Inbred F344; Receptors, CCR2; Receptors, Chemokine; RNA, Messenger; Viral Proteins; Virulence Factors | 2004 |
Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Imidazoles; Kidney; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WF; Receptor, Angiotensin, Type 1; Signal Transduction; Sympathetic Nervous System; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents | 2005 |
Angiotensin AT2 receptor contributes to cardiovascular remodelling of aged rats during chronic AT1 receptor blockade.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Fibrosis; Heart Rate; Hypertrophy; Imidazoles; Myocardium; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Telemetry; Tetrazoles; Ventricular Remodeling | 2004 |
Angiotensin II: a devious activator of mineralocorticoid receptor-dependent gene expression.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aging; Aldosterone; Angiotensin II; Gene Expression Profiling; Gene Expression Regulation; Humans; Muscle, Smooth, Vascular; Oligonucleotide Array Sequence Analysis; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Transcriptional Activation | 2005 |
Characterization of the protective effects of cardiotrophin-1 against non-ischemic death stimuli in adult cardiomyocytes.
Topics: Aging; Angiotensin II; Animals; Antigens, CD; bcl-Associated Death Protein; Cardiotonic Agents; Carrier Proteins; Cell Death; Cells, Cultured; Cytokine Receptor gp130; Cytokines; DNA-Binding Proteins; Hydrogen Peroxide; Male; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Ischemia; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; STAT3 Transcription Factor; Trans-Activators | 2005 |
Postnatal development of the secretory activity of the goat subcommissural organ. A Reissner's fibre and angiotensin II immunohistochemical study.
Topics: Aging; Angiotensin II; Animals; Glycoproteins; Goats; Immunohistochemistry; Nerve Fibers; Subcommissural Organ | 2005 |
Growing old, angiotensin II, cardiac hypertrophy, and death: making the connection with p66Shc.
Topics: Adaptor Proteins, Signal Transducing; Aging; Angiotensin II; Animals; Cardiomegaly; Humans; Hypertension; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1 | 2005 |
Angiotensin II-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure.
Topics: Aging; Angiotensin II; Angiotensinogen; Animals; Calcium; Calcium-Transporting ATPases; Cardiac Output, Low; Cardiomegaly; Cardiomyopathy, Dilated; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Phenotype; Promoter Regions, Genetic; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Remodeling | 2005 |
Altered cardiovascular responses to chronic angiotensin II infusion in aged rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Circadian Rhythm; Heart Rate; Male; Rats; Rats, Wistar | 2005 |
Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats.
Topics: Adrenergic alpha-Agonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Western; Carotid Arteries; Collagen; Dipeptides; Immunohistochemistry; Losartan; Male; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Culture Techniques; Phenylephrine; Protease Inhibitors; Rats; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Tunica Intima; Vasoconstrictor Agents | 2005 |
Prenatal cocaine alone and combined with nicotine alters ANG II and IGF-1 induced left atrial contractions in aging male offspring.
Topics: Aging; Angiotensin II; Animals; Atrial Function, Left; Cardiotonic Agents; Cocaine; Female; Heart Atria; Insulin-Like Growth Factor I; Male; Myocardial Contraction; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2005 |
Growth hormone replacement attenuates diastolic dysfunction and cardiac angiotensin II expression in senescent rats.
Topics: Aging; Angiotensin II; Animals; Diastole; Growth Hormone; Heart; Hormone Replacement Therapy; Myocardium; Rats; Rats, Inbred BN; Rats, Inbred F344; Time Factors; Ventricular Dysfunction, Left | 2006 |
Plasma angiotensin II concentrations in the early neonatal period.
Topics: Aging; Angiotensin II; Birth Weight; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Very Low Birth Weight | 2006 |
Role of angiotensin II and endothelin-1 receptors in aging-related functional changes in rat cardiovascular system.
Topics: Aging; Angiotensin II; Animals; Cardiovascular System; Gene Expression; In Vitro Techniques; Male; Rats; Rats, Inbred F344; Receptor, Endothelin A | 2006 |
Early aging and anatomic heterogeneity determine cyclooxygenase-mediated vasoconstriction to angiotensin II in mice.
Topics: Aging; Angiotensin II; Animals; Blood Vessels; Male; Meclofenamic Acid; Mice; Mice, Inbred C57BL; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Vasoconstriction | 2006 |
Do cardiac neuropeptides play a role in the occurrence of atrial fibrillation after coronary bypass surgery?
Topics: Adrenergic beta-Antagonists; Aging; Angiotensin II; Atrial Fibrillation; Coronary Artery Bypass; Diabetes Complications; Echocardiography; Female; Humans; Male; Middle Aged; Mitral Valve; Myocardium; Neuropeptide Y; Postoperative Period; Prospective Studies; Sodium; Stroke Volume; Substance P | 2007 |
Characterization of heart size and blood pressure in the vitamin D receptor knockout mouse.
Topics: Aging; Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Heart; Ions; Mice; Mice, Knockout; Organ Size; Phenotype; Receptors, Calcitriol; Renin | 2007 |
Sex and age differences of renal function in rats with reduced ANG II activity during the nephrogenic period.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Blood Pressure; Body Weight; Creatinine; Dehydration; Female; Glomerular Filtration Rate; Kidney; Male; Osmolar Concentration; Pregnancy; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Sex Characteristics | 2007 |
Developmental activity of the renin-angiotensin system during the "critical period" modulates later L-NAME-induced hypertension and renal injury.
Topics: Aging; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Cardiovascular System; Critical Period, Psychological; Drug Administration Schedule; Enzyme Inhibitors; Hypertension; Kidney; Male; Mortality; NG-Nitroarginine Methyl Ester; Oxidative Stress; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Tetrazoles; Vasoconstrictor Agents | 2007 |
Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.
Topics: Adaptor Proteins, Signal Transducing; Aging; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Blotting, Western; Cardiomyopathy, Dilated; Class Ib Phosphatidylinositol 3-Kinase; Irbesartan; Isoenzymes; Luminescent Measurements; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Oxidative Stress; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tetrazoles | 2007 |
Protective effect of long-term angiotensin II inhibition.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Body Weight; Cardiovascular System; Enalapril; Losartan; Male; Myocardium; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Renin-Angiotensin System | 2007 |
Long-term AT1 receptor blockade improves metabolic function and provides renoprotection in Fischer-344 rats.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Imidazoles; Insulin; Kidney; Leptin; Male; Metabolic Syndrome; Metabolism; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles | 2007 |
Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Congenic; Blood Pressure; C-Reactive Protein; Cell Adhesion Molecules; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Membrane Proteins; Ovariectomy; Peptide Fragments; Proteinuria; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 2007 |
Kidney-specific enhancement of ANG II stimulates endogenous intrarenal angiotensinogen in gene-targeted mice.
Topics: Aging; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Humans; Kidney; Male; Mice; Mice, Transgenic; Organ Specificity; Renin | 2007 |
Different responses to angiotensin-(1-7) in young, aged and diabetic rabbit corpus cavernosum.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erectile Dysfunction; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penis; Peptide Fragments; Peptides; Potassium Channel Blockers; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Failure of antioxidants to protect against angiotensin II-induced aortic rupture in aged apolipoprotein(E)-deficient mice.
Topics: Aging; Angiotensin II; Animals; Antioxidants; Aortic Rupture; Apolipoproteins E; Blood Pressure; Blotting, Western; Creatinine; Heme Oxygenase-1; Humans; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Oxidative Stress; Proteinuria; Thiobarbituric Acid Reactive Substances; U937 Cells | 2007 |
Relationships between endogenous sex hormone concentrations and vascular function in postmenopausal women.
Topics: Aged; Aging; Angiotensin II; Blood Pressure; Body Mass Index; Cardiovascular Physiological Phenomena; Estradiol; Female; Gonadal Steroid Hormones; Humans; Middle Aged; Postmenopause; Progesterone; Renin-Angiotensin System; Sodium; Vascular Resistance; Water-Electrolyte Balance | 2007 |
Protein kinase CK2 links extracellular growth factor signaling with the control of p27(Kip1) stability in the heart.
Topics: Aging; Angiotensin II; Animals; Cardiomegaly; Casein Kinase II; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Myocardium; Myocytes, Cardiac; Protein Binding; Rats; Signal Transduction | 2008 |
Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Male; Neuroglia; Peptide Fragments; Rats; Renin-Angiotensin System; Solitary Nucleus; Tetrazoles | 2008 |
Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats.
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Diabetes Mellitus, Type 2; Endothelium, Vascular; Imidazoles; Losartan; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; rho-Associated Kinases; Signal Transduction; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2008 |
Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells.
Topics: Aging; Angiotensin II; Animals; Aorta; Calpain; Male; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Protein Biosynthesis; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription, Genetic | 2008 |
Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney.
Topics: Abnormalities, Drug-Induced; Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Animals, Newborn; Autoradiography; Female; Imidazoles; Kidney; Kidney Glomerulus; Losartan; Pregnancy; Pregnancy, Animal; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2008 |
Pulmonary vascular changes in young and aging rats exposed to 5,486 m altitude.
Topics: Aging; Altitude; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Dose-Response Relationship, Drug; Hematocrit; Hypoxia; Male; Muscle, Smooth, Vascular; Polycythemia; Pulmonary Circulation; Rats; Rats, Inbred Strains; Vasoconstriction | 1984 |
Postnatal development of the renin-angiotensin system in rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Endopeptidases; Kidney; Male; Rats; Renin | 1980 |
Renin-angiotensin-aldosterone system.
Topics: Aging; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Humans; Hypertension; Renal Veins; Renin; Sodium | 1980 |
Angiotensin II metabolism by tissues from developing rats.
Topics: Aging; Angiotensin II; Animals; Endopeptidases; In Vitro Techniques; Kidney; Liver; Male; Peptide Fragments; Rats | 1981 |
MK 421 and prevention of genetic hypertension development in young spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Dipeptides; Enalapril; Hemodynamics; Hypertension; Male; Norepinephrine; Rats | 1982 |
Renal and adrenal responses to converting-enzyme inhibition in fetal and newborn life.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Captopril; Fetal Blood; Kidney; Proline; Sheep | 1983 |
Comparative study of active and inactive plasma renin in healthy infants and adults.
Topics: Adult; Aging; Angiotensin II; Female; Humans; Infant; Kinetics; Male; Middle Aged; Radioimmunoassay; Reference Values; Renin | 1983 |
The natural history of salt-wasting disorders of adrenal and renal origin.
Topics: 18-Hydroxycorticosterone; Adolescent; Adrenal Insufficiency; Adult; Aging; Aldosterone; Angiotensin II; Desoxycorticosterone; Dexamethasone; Female; Humans; Hydrocortisone; Infant; Infant, Newborn; Kidney Diseases; Kidney Tubules; Male; Potassium; Renin; Sodium Chloride; Water-Electrolyte Imbalance | 1984 |
Prostaglandin production and cellular aging.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aging; Angiotensin II; Cells, Cultured; Dinoprost; Dinoprostone; Epinephrine; Fibroblasts; Humans; Lung; Male; Middle Aged; Prostaglandins; Prostaglandins E; Prostaglandins F; Thrombin; Thromboxane B2 | 1981 |
Altered vascular responsiveness in isolated perfused lungs from aging rats.
Topics: 5-Hydroxytryptophan; Aging; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Male; Pulmonary Artery; Rats; Rats, Inbred Strains; Vasoconstriction | 1982 |
Postnatal changes in urinary prostaglandin E excretion in premature infants.
Topics: Aging; Aldosterone; Angiotensin II; Humans; Infant; Infant, Newborn; Infant, Premature; Kidney; Male; Natriuresis; Prostaglandins E; Regional Blood Flow; Renin | 1980 |
Mechanism of age-related changes in renin and adrenocortical steroids.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aging; Aldosterone; Angiotensin II; Corticosterone; Desoxycorticosterone; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hydrocortisone; Male; Middle Aged; Renin | 1980 |
Hypertension in the elderly.
Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Vessels; Blood Volume; Brain; Heart; Humans; Hypertension; Middle Aged; Renin; Risk; Sympathetic Nervous System | 1980 |
Different patterns in essential hypertension and possible choice of antihypertensive drugs.
Topics: Adult; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Cardiac Output; Catecholamines; Female; Humans; Hypertension; Male; Middle Aged; Renin; Vascular Resistance | 1980 |
Plasma aldosterone response to angiotensin II in sodium-restricted elderly subjects with essential hypertension.
Topics: Aged; Aging; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hypertension; Infusions, Intra-Arterial; Male; Middle Aged; Renin | 1981 |
Renin and angiotensin levels in children.
Topics: Aging; Angiotensin II; Blood Pressure; Body Weight; Child; Child, Preschool; Female; Humans; Infant; Male; Reference Values; Renin; Sex Factors; Sodium; Urea | 1981 |
Ontogeny of blood pressure and the renin-angiotensin-aldosterone system. Sequential studies in the newborn lamb.
Topics: Aging; Aldosterone; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Dexamethasone; Female; Hydrocortisone; Renin; Sheep; Sodium | 1981 |
Racial difference in salivary sodium-potassium ratio in low renin essential hypertension.
Topics: Adult; Aged; Aging; Angiotensin II; Black People; Humans; Hypertension; Middle Aged; Potassium; Racial Groups; Renin; Saliva; Sodium; White People | 1982 |
Lead, hypertension, and the renin-angiotensin system in rats.
Topics: Aging; Angiotensin II; Animals; Creatinine; Female; Hypertension; Lead; Organ Size; Potassium; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Renin-Angiotensin System; Sodium | 1982 |
Effect of age on specific angiotensin II-binding sites in rat brain.
Topics: Aging; Angiotensin II; Animals; Brain; Cell Membrane; Kinetics; Organ Specificity; Rats; Receptors, Drug | 1980 |
Alterations in renal vascular resistance and reactivity in spontaneous hypertension of rats.
Topics: Aging; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Norepinephrine; Rats; Serotonin; Vascular Resistance; Vasopressins | 1980 |
Effect of saralasin and indomethacin on renal function in developing piglets.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Indomethacin; Kidney; Prostaglandins; Regional Blood Flow; Saralasin; Sodium; Swine | 1980 |
Vascular reactivity to angiotensin and noradrenaline in rats. Effect of aging and of uninephrectomy.
Topics: Aging; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Hormones; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nephrectomy; Norepinephrine; Portal Vein; Rats; Systole; Vasoconstriction; Vasoconstrictor Agents | 1980 |
Vascular reactivity to angiotensin and noradrenaline in spontaneously and renal hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Female; Hormones; Hypertension; Hypertension, Renal; Male; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Rats; Stimulation, Chemical | 1980 |
Age-rated profile of cardiovascular reactivity to norepinephrine and angiotensin II in normal and hypertensive man.
Topics: Adult; Aging; Angiotensin II; Female; Hemodynamics; Humans; Hypertension; Male; Norepinephrine | 1980 |
Developmental regulation of ACE gene expression by endogenous kinins and angiotensin II.
Topics: Adrenergic beta-Antagonists; Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aprotinin; Blood Pressure; Bradykinin; Gene Expression Regulation; Kallikreins; Kidney; Kininogens; Kinins; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1995 |
Endocrine consequences of prenatal sodium depletion prepare rats for high need-free NaCl intake in adulthood.
Topics: Aging; Aldosterone; Angiotensin II; Animals; Appetite; Diet; Endocrine Glands; Female; Fetus; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sodium; Sodium Chloride | 1995 |
Autoregulation of cochlear blood flow in young and aged mice.
Topics: Age Factors; Aging; Angiotensin II; Animals; Blood Pressure; Cochlea; Homeostasis; Male; Mice; Presbycusis | 1995 |
Angiotensin II induces cardiovascular hypertrophy in perindopril-treated rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arterioles; Cardiovascular System; Hypertrophy; Indoles; Male; Muscle, Smooth, Vascular; Perindopril; Ploidies; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation | 1995 |
Actions of norepinephrine and angiotensin II on aortic rings of adult and aged normotensive and hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Aorta; Hypertension; In Vitro Techniques; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tachyphylaxis; Vasoconstriction | 1993 |
No evidence for a general change in contractile responsiveness of the mesenteric artery with aging.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Angiotensin II; Calcium; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Prostaglandin Endoperoxides, Synthetic; Serotonin; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1995 |
Age-related changes in angiotensin II-stimulated vascular contraction and inositol phosphate accumulation in Fischer 344 rats.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arteries; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Inositol Phosphates; Losartan; Male; Pyridines; Rats; Rats, Inbred F344; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1994 |
Thromboxane A2-prostaglandin H2 and renovascular hypertension in rats.
Topics: Aging; Angiotensin II; Animals; Arginine Vasopressin; Baroreflex; Blood Pressure; Body Weight; Caprylates; Cyclooxygenase Inhibitors; Diastole; Furosemide; Heart; Heart Conduction System; Heart Rate; Heart Ventricles; Hypertension, Renovascular; Kidney; Male; Nitroprusside; Norepinephrine; Organ Size; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Reference Values; Sulfonamides; Systole; Time Factors; Vasoconstriction | 1994 |
Altered renal vascular responses in the aging rat kidney.
Topics: Aging; Angiotensin II; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Endothelins; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Renal Circulation; Tetrazoles | 1994 |
Improved HPLC-radioimmunoassay for quantifying angiotensin II in plasma.
Topics: Adult; Aged; Aged, 80 and over; Aging; Angiotensin II; Chromatography, High Pressure Liquid; Diet; Female; Furosemide; Humans; Male; Radioimmunoassay; Reference Values; Sensitivity and Specificity; Sodium, Dietary | 1994 |
Oxytocin response to challenging stimuli in elderly men.
Topics: Adult; Aged; Aged, 80 and over; Aging; Angiotensin II; Apomorphine; Blood Glucose; Blood Pressure; Heart Rate; Humans; Infusions, Intravenous; Injections, Intravenous; Injections, Subcutaneous; Insulin; Male; Middle Aged; Oxytocin | 1994 |
Ontogeny of angiotensin-II-induced prolactin release in vivo and in vitro in female and male rats.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Losartan; Male; Pituitary Gland; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors | 1994 |
Angiotensin II in brown adipose tissue from young and adult Zucker obese and lean rats.
Topics: Adipose Tissue, Brown; Aging; Angiotensin II; Animals; Female; Male; Neurons; Norepinephrine; Obesity; Rats; Rats, Zucker; Reference Values; Renin-Angiotensin System | 1994 |
Arterial alpha-adrenergic responsiveness is decreased and SNS activity is increased in older humans.
Topics: Adult; Aged; Aging; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Brachial Artery; Epinephrine; Female; Forearm; Guanidines; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Muscle Development; Muscle, Smooth, Vascular; Muscles; Norepinephrine; Receptors, Adrenergic, alpha; Regional Blood Flow; Up-Regulation | 1994 |
Variable effects of endothelin-1 on [Ca2+]i transients, pHi, and contraction in ventricular myocytes.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Calcium; Cell Movement; Cells, Cultured; Chick Embryo; Endothelins; Heart Ventricles; Hydrogen-Ion Concentration; Intracellular Membranes; Myocardial Contraction; Myocardium; Rabbits; Rats; Tetradecanoylphorbol Acetate | 1993 |
Aging and human hormonal and pressor responsiveness to angiotensin II infusion with simultaneous measurement of exogenous and endogenous angiotensin II.
Topics: Adult; Aged; Aging; Aldosterone; Angiotensin Amide; Angiotensin II; Blood Platelets; Blood Pressure; Female; Heart Rate; Hormones; Humans; Infusions, Intravenous; Male; Middle Aged; Radioimmunoassay; Receptors, Angiotensin | 1993 |
Long-term low-dose angiotensin converting enzyme inhibitor treatment increases vascular cyclic guanosine 3',5'-monophosphate.
Topics: Aging; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Bradykinin; Cyclic GMP; Dose-Response Relationship, Drug; Female; Hypertension; In Vitro Techniques; Indoles; Maternal-Fetal Exchange; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Perindopril; Pregnancy; Ramipril; Rats; Rats, Inbred SHR; Reference Values; Systole | 1993 |
Angiotensin II/prostaglandin I2 interactions in spontaneously hypertensive rats.
Topics: Aging; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Captopril; Cardiac Output; Dose-Response Relationship, Drug; Drug Interactions; Epoprostenol; Hemodynamics; Indomethacin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Splanchnic Circulation; Vascular Resistance | 1993 |
Renal responses to acute angiotensin II inhibition and administered angiotensin II in the aging, conscious, chronically catheterized rat.
Topics: Age Factors; Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Sprague-Dawley; Renal Plasma Flow; Tetrazoles | 1993 |
Vascular conversion of angiotensin I in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Hindlimb; Hypertension; Male; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Age-related change in plasma aldosterone response to exogenous angiotensin II in the rat.
Topics: Adrenal Cortex; Aging; Aldosterone; Angiotensin II; Animals; Captopril; Corticosterone; Dexamethasone; Female; Kinetics; Potassium; Rats | 1993 |
Effects of aging on cerebral vascular responses to serotonin in rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Male; Rats; Rats, Wistar; Serotonin | 1993 |
Ageing and blood pressure regulation: dose-response relationships for angiotensin, blood pressure, atrial natriuretic peptide and aldosterone in normal subjects of varying ages.
Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Radioimmunoassay | 1993 |
Glomerular angiotensin II receptor subtypes during development of rat kidney.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Autoradiography; Fetus; Kidney; Kidney Glomerulus; Kidney Medulla; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tissue Distribution | 1993 |
Angiotensin II (AII) and adrenal gland AII receptors in rats with congenital hypothyroidism.
Topics: Adrenal Glands; Aging; Angiotensin II; Animals; Animals, Newborn; Congenital Hypothyroidism; Hypothyroidism; Isomerism; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, Angiotensin; Renin | 1993 |
Salt-deficient diet and early weaning inhibit DNA synthesis in immature rat proximal tubular cells.
Topics: Aging; Angiotensin II; Animals; Body Weight; Diet; DNA; Eating; Kidney Tubules, Proximal; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sodium; Weaning | 1993 |
Renal and systemic adaptation to sodium restriction in aging rats.
Topics: Aging; Angiotensin II; Animals; Diet, Sodium-Restricted; Female; Hemodynamics; Hormones; Kallikreins; Kidney; Rats; Rats, Wistar; Renin | 1993 |
Angiotensin II-induced endothelium-dependent relaxation of fowl aorta.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Aorta; Arginine; Calcium; Endothelium, Vascular; Female; Gossypol; Hydroquinones; NG-Nitroarginine Methyl Ester; Poultry; Vasoconstrictor Agents; Vasodilation | 1993 |
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Hydralazine; Hydrochlorothiazide; Hypertension; Linear Models; Muscle Contraction; Muscle, Smooth, Vascular; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1995 |
Activation of angiotensin-generating systems in the developing rat kidney.
Topics: Aging; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Female; Gene Expression; Humans; Kidney; Male; Peptidyl-Dipeptidase A; Pregnancy; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1996 |
Plasma neuro-endocrine activity in very elderly subjects and patients with and without heart failure.
Topics: Aged; Aged, 80 and over; Aging; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Diuretics; Female; Heart Failure; Humans; Linear Models; Male; Norepinephrine; Reference Values; Renin; Renin-Angiotensin System | 1995 |
The AT2 receptor selectively associates with Gialpha2 and Gialpha3 in the rat fetus.
Topics: Adenosine Diphosphate Ribose; Aging; Angiotensin II; Animals; Animals, Newborn; Antibody Specificity; Cell Membrane; Fetus; Gene Expression Regulation, Developmental; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Immunoblotting; Kinetics; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Virulence Factors, Bordetella | 1996 |
Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth factor regulation.
Topics: Aging; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Gene Expression; Growth Substances; Homeostasis; Kidney; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Mice; Mice, Knockout; Mice, Mutant Strains; Organ Size; Platelet-Derived Growth Factor; Restriction Mapping; RNA, Messenger; Transforming Growth Factor beta | 1995 |
Sustained transgene expression by transfection of renin gene into liver of neonates.
Topics: Aging; Angiotensin II; Animals; Animals, Genetically Modified; Animals, Newborn; Base Sequence; Blood Pressure; Chloramphenicol O-Acetyltransferase; DNA Primers; Genetic Vectors; Immunohistochemistry; Liver; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Renin; Renin-Angiotensin System | 1996 |
Variation of intrarenal angiotensin II and angiotensin II receptors by acute renal ischemia in the aged rat.
Topics: Acute Disease; Aging; Angiotensin II; Animals; Creatinine; Ischemia; Kidney; Kidney Glomerulus; Male; Random Allocation; Rats; Rats, Wistar; Receptors, Angiotensin; RNA, Messenger | 1996 |
Hypotensive and reflex bradycardic effects of ketanserin, but not of prazosin, enhanced selectively in aging conscious rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Injections, Intravenous; Ketanserin; Male; Nitroprusside; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasoconstrictor Agents | 1996 |
Age-related decline in thirst and sodium appetite in rats related to kininase II inhibition.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Drinking; Female; Rats; Rats, Inbred F344; Sodium Chloride, Dietary | 1996 |
Angiotensin II receptors in the human adrenal gland.
Topics: Adrenal Glands; Adult; Aging; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Gestational Age; Humans; Imidazoles; Losartan; Middle Aged; Pyridines; Receptors, Angiotensin; Tetrazoles; Tissue Distribution | 1996 |
Age-related differences and roles of endothelial nitric oxide and prostanoids in angiotensin II responses of isolated, perfused mesenteric arteries and veins of rats.
Topics: Aging; Angiotensin II; Animals; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Perfusion; Potassium Chloride; Prostaglandins; Rats; Rats, Wistar; Vasoconstrictor Agents | 1997 |
Reversing congestive heart failure with endothelin receptor antagonists.
Topics: Aging; Angiotensin II; Animals; Bosentan; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Humans; Mice; Mice, Transgenic; Rabbits; Receptors, Endothelin; Sulfonamides | 1997 |
Effects of age and gender on the AII-induced stimulation of prolactin release and inositol phosphate accumulation in rat anterior pituitary cells in vitro.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; In Vitro Techniques; Inositol Phosphates; Male; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Sprague-Dawley; Saralasin; Sex Characteristics | 1997 |
The increase in blood pressure induced by inhibition of nitric oxide synthase in anesthetized Wistar rats is inversely related to basal blood pressure value.
Topics: Aging; Anesthesia, General; Angiotensin II; Animals; Blood Pressure; Enzyme Inhibitors; Ganglionic Blockers; Hexamethonium Compounds; Male; Methylguanidine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Vasoconstrictor Agents | 1997 |
Plasma renin activity and metabolic clearance rate of angiotensin II in the unstressed aging rat.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Renin | 1997 |
Sensitivity of the segmental renal arterioles to angiotensin II in the aging rat.
Topics: Aging; Angiotensin II; Animals; Arterioles; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstrictor Agents | 1997 |
Vasopressin V2 receptor mRNA expression and cAMP accumulation in aging rat kidney.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Angiotensin II; Animals; Chick Embryo; Cyclic AMP; Dehydration; Dose-Response Relationship, Drug; Female; Hydrolysis; Loop of Henle; Osmolar Concentration; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Receptors, Vasopressin; RNA, Messenger; Vasopressins | 1997 |
Angiotensin II and myocyte growth: role of fibroblasts.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Biphenyl Compounds; Cell Division; Culture Media, Conditioned; Dose-Response Relationship, Drug; Fibroblasts; Imidazoles; Losartan; Myocardium; Rats; Rats, Wistar; Tetrazoles; Time Factors | 1997 |
Short-term lisinopril treatment in old rats worsens impairment of angiotensin-induced reflex bradycardia.
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Bradycardia; Lisinopril; Male; Phenylephrine; Rats; Rats, Sprague-Dawley | 1997 |
Pivotal role of the renin-angiotensin system in Lyon hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiac Output; Enzyme Precursors; Heart Rate; Hemodynamics; Hypertension; Indoles; Kidney Cortex; Male; Perindopril; Rats; Rats, Inbred Strains; Regional Blood Flow; Renin; Renin-Angiotensin System; Vascular Resistance | 1997 |
Role of angiotensin II in the regulation of a novel vascular modulator, hepatocyte growth factor (HGF), in experimental hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Enalapril; Gene Expression Regulation, Developmental; Heart; Hepatocyte Growth Factor; Humans; Hypertension; Imidazoles; Losartan; Lung; Male; Myocardium; Organ Specificity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regression Analysis | 1997 |
AT1 receptor antagonist treatment caused persistent arterial functional changes in young spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Electric Stimulation; Heart; Hypertension; Imidazoles; Kidney; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1997 |
Response of proximal tubules to angiotensin II changes during maturation.
Topics: Absorption; Aging; Angiotensin II; Animals; Blood Pressure; Cyclic AMP; Hemodynamics; In Vitro Techniques; Kidney Tubules, Proximal; Male; Nephrons; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Vascular Resistance | 1998 |
Structure and reactivity of small arteries in aging.
Topics: Aging; Angiotensin II; Animals; Basilar Artery; Blood Pressure; Female; Mesenteric Arteries; Nitroprusside; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1998 |
Cardiac senescence is associated with enhanced expression of angiotensin II receptor subtypes.
Topics: Aging; Angiotensin II; Animals; Gene Expression; Heart; Heart Ventricles; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger | 1998 |
Protectant activity of hexarelin or growth hormone against postischemic ventricular dysfunction in hearts from aged rats.
Topics: 6-Ketoprostaglandin F1 alpha; Aging; Angiotensin II; Animals; Growth Hormone; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Oligopeptides; Protective Agents; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left | 1998 |
Assessment of vasoactive agents and vascular aging by the second derivative of photoplethysmogram waveform.
Topics: Aged; Aging; Angiotensin II; Aorta; Blood Pressure; Female; Humans; Male; Middle Aged; Nitroglycerin; Photoplethysmography; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Effects of sustained flow reduction on postnatal intestinal circulation.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Hemodynamics; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Intestine, Small; Isometric Contraction; Mesenteric Arteries; Muscle Development; Muscle, Smooth; Muscle, Smooth, Vascular; omega-N-Methylarginine; Oxygen Consumption; Peptides; Perfusion; Regional Blood Flow; Swine; Vascular Resistance | 1998 |
Perinatal ANG II programs adult blood pressure, glomerular number, and renal function in rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Female; Kidney; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1998 |
Factors involved in the effects of losartan on endothelial dysfunction induced by aging in SHR.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Kidney; Losartan; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitrites; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents; Vasodilation | 1998 |
Involvement of angiotensin II in development of spontaneous nephrosis in Dahl salt-sensitive rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Body Weight; Calcium Channel Blockers; Cholesterol; Glucocorticoids; Hypertension; Imidazoles; Imidazolidines; Losartan; Male; Methylprednisolone; Nephrosis; Proteinuria; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Verapamil | 1998 |
Changes in angiotensin II receptors in dopamine-rich regions of the mouse brain with age and ethanol consumption.
Topics: Aging; Angiotensin II; Animals; Autoradiography; Brain; Caudate Nucleus; Dopamine; Ethanol; Female; Globus Pallidus; Imidazoles; Iodine Radioisotopes; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Protein Binding; Putamen; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1999 |
Age-related responses of vasoactive factors during acute exercise.
Topics: Adrenomedullin; Adult; Aged; Aged, 80 and over; Aging; Angiotensin II; Atrial Natriuretic Factor; Cyclic AMP; Cyclic GMP; Exercise; Female; Humans; Male; Peptides; Reference Values; Vasodilator Agents | 1998 |
Role of AT2 receptors in angiotensin II-stimulated contraction of small mesenteric arteries in young SHR.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction | 1999 |
Effects of systemic hypotension on postnatal intestinal circulation: role of angiotensin.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Hemodynamics; Hypotension; In Vitro Techniques; Intestinal Mucosa; Intestines; Losartan; Oligopeptides; Oxygen Consumption; Regional Blood Flow; Swine; Vascular Resistance; Vasoconstriction | 1999 |
Diet enriched with procyanidins enhances antioxidant activity and reduces myocardial post-ischaemic damage in rats.
Topics: Aging; Angiotensin II; Animals; Antioxidants; Ascorbic Acid; Biflavonoids; Blood Glucose; Body Weight; Catechin; Cholesterol; Chromans; Creatine Kinase; Dietary Supplements; Epoprostenol; Heart; Male; Myocardial Reperfusion Injury; Myocardium; Proanthocyanidins; Rats; Rats, Wistar; Triglycerides; Uric Acid; Vitamin E | 1999 |
Sympathetic nervous system activity and alpha-adrenergic responsiveness in older hypertensive humans.
Topics: Adenylyl Cyclases; Aged; Aging; Angiotensin II; Blood Platelets; Epinephrine; Female; Forearm; GTP-Binding Proteins; Humans; Hypertension; Kinetics; Male; Middle Aged; Norepinephrine; Receptors, Adrenergic, alpha; Regional Blood Flow; Sympathetic Nervous System | 1999 |
Abated cardiovascular responses to chronic oral lisinopril treatment in conscious elderly rats.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Blood Pressure; Body Weight; Bradycardia; Consciousness; Drinking; Lisinopril; Male; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Sympathomimetics; Vasoconstrictor Agents | 1999 |
Angiotensin II stimulates platelet-derived growth factor-B chain expression in newborn rat vascular smooth muscle cells and neointimal cells through Ras, extracellular signal-regulated protein kinase, and c-Jun N-terminal protein kinase mechanisms.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression; Genes, ras; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transcription Factors; Tunica Intima | 1999 |
Age-related impairment of aldosterone secretion in zona glomerulosa cells of ovariectomized rats.
Topics: Adrenocorticotropic Hormone; Aging; Aldosterone; Angiotensin II; Animals; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP; Cytochrome P-450 CYP11B2; Female; Ovariectomy; Radioimmunoassay; Rats; Zona Glomerulosa | 1999 |
Differential modulation of nitric oxide and prostacyclin release in senescent rat heart stimulated by angiotensin II.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Atrial Natriuretic Factor; Coronary Circulation; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Heart; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Perfusion; Rats; Rats, Inbred F344; Time Factors; Vasoconstriction | 1999 |
Differential effects of losartan and doxazosin on vascular function in senescent spontaneously hypertensive rats.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Doxazosin; Endothelium, Vascular; Hypertension; Losartan; Male; Nitrates; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasodilation; Vasodilator Agents | 1999 |
Aging is associated with endothelial dysfunction in the human forearm vasculature.
Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Angiotensin II; Brachial Artery; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Plethysmography; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 2000 |
Aging differentially modifies sensitivity of nerve blood flow to vasocontractile agents (endothelin-1, noradrenaline and angiotensin II) in sciatic nerve.
Topics: Aging; Angiotensin II; Animals; Arterioles; Blood Pressure; Endothelin-1; Norepinephrine; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Vasoconstrictor Agents | 2000 |
Onset of glomerular hypertension with aging precedes injury in the spontaneously hypertensive rat.
Topics: Aging; Angiotensin II; Animals; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hypertension, Renal; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Punctures; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation | 2000 |
Effect of aging on the arginine-vasopressin response to physostigmine and angiotensin II in normal men.
Topics: Adult; Aged; Aging; Angiotensin II; Arginine Vasopressin; Cholinesterase Inhibitors; Clinical Chemistry Tests; Humans; Male; Middle Aged; Physostigmine; Vasoconstrictor Agents | 2000 |
Angiotensin-converting enzyme inhibitor prevents age-related endothelial dysfunction.
Topics: Acetylcholine; Administration, Oral; Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biological Factors; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; Heart Rate; Hydralazine; Hydrochlorothiazide; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Inbred WKY; Vasodilation | 2000 |
Angiotensin II enhances beta-adrenergic receptor-mediated vasorelaxation in aortas from young but not old rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Angiotensin II; Animals; Aorta, Thoracic; Bucladesine; Colforsin; Cyclic AMP; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Phosphodiesterase Inhibitors; Pyridines; Rats; Rats, Inbred F344; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents; Vasodilation | 2000 |
Reduced feeding response to neuropeptide Y in senescent Fischer 344 rats.
Topics: Aging; Angiotensin II; Animals; Body Weight; Cerebral Ventricles; Dose-Response Relationship, Drug; Energy Intake; Feeding Behavior; Humans; Injections, Intraventricular; Male; Neuropeptide Y; Rats; Rats, Inbred F344; Time Factors; Weight Gain; Weight Loss | 2001 |
Perinatal dietary NaCl level: effect on angiotensin-induced thermal and dipsogenic responses in adult rats.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Body Temperature; Diet; Drinking Behavior; Female; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Vasoconstrictor Agents | 2001 |
Paradoxically enhanced endothelin-B receptor-mediated vasoconstriction in conscious old monkeys.
Topics: Aging; Angiotensin II; Animals; Consciousness; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Macaca fascicularis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides, Cyclic; Phenylephrine; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2001 |
Age-dependent activation of PKC isoforms by angiotensin II in the proximal nephron.
Topics: Age Factors; Aging; Angiotensin II; Animals; Blotting, Western; Enzyme Activation; Isoenzymes; Kidney Tubules, Proximal; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Sprague-Dawley | 2001 |
Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Enalapril; Losartan; Male; NADPH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Reference Values; Time Factors | 2001 |
Effects of angiotensin II on the renal antioxidant activities of borderline hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Female; Glutathione; Humans; Hypertension; Injections, Subcutaneous; Lipid Peroxides; Male; Oxidoreductases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Vasoconstrictor Agents; Weaning | 2001 |
Cellular signaling, AGE accumulation and gene expression in hepatocytes of lean aging rats fed ad libitum or food-restricted.
Topics: Aging; Angiotensin II; Animals; Body Weight; Cells, Cultured; Cyclic AMP; Female; Food Deprivation; Gene Expression; Glucagon; Glycation End Products, Advanced; Hepatocytes; Liver; Organ Size; Rats; Rats, Wistar; Signal Transduction; Vasopressins | 2002 |
Ontogeny of angiotensin II type 1 receptor mRNAs in fetal and neonatal rat brain.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Brain; Cardiovascular Physiological Phenomena; Diencephalon; Female; Fetus; Homeostasis; In Situ Hybridization; Male; Mesencephalon; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Rhombencephalon; RNA, Messenger; Telencephalon; Water-Electrolyte Balance | 2001 |
Effect on aging on plasma renin and aldosterone in normal man.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aging; Aldosterone; Angiotensin II; Blood; Blood Pressure; Female; Glomerular Filtration Rate; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Posture; Potassium; Renin; Sodium; Water-Electrolyte Balance | 1975 |
[Essential hypertension: adrenergic control system, renin-angiotensin effector axis, kidney and age].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Angiotensin II; Catecholamines; Diuretics; Humans; Hypertension; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Renin; Vasodilator Agents | 1976 |
Renin and age as determinants of a predominantly betablocker-based antihypertensive drug program.
Topics: Adrenergic beta-Antagonists; Adult; Aging; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Feedback; Humans; Hypertension; Middle Aged; Norepinephrine; Oxprenolol; Propranolol; Renin | 1976 |
Effects of age on aortic pressure-diameter and elastic stiffness-stress relationships in unanesthetized sheep.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Aorta; Blood Pressure; Elasticity; Female; Hemodynamics; Methoxamine; Muscle, Smooth; Nitroglycerin; Pregnancy; Sheep; Stress, Mechanical | 1979 |
Effect of age on angiotensin II receptors from rat brain.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Brain; Cell Membrane; Male; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Saralasin; Tissue Distribution | 1979 |
Plasma catecholamines determination using high pressure liquid chromatography and their roles in blood pressure regulation and experimental hypertension in rats.
Topics: Aging; Anesthesia; Angiotensin II; Animals; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Circadian Rhythm; Hemorrhage; Hydroxydopamines; Hypertension; Male; Rats; Sodium | 1979 |
Clinical, biochemical and pathological features of low-renin ("primary") hyperaldosteronism.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aging; Angiotensin II; Angiotensinogen; Carbon Dioxide; Corticosterone; Desoxycorticosterone; Female; Humans; Hyperaldosteronism; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Potassium; Renin; Sodium; Urea; Vascular Diseases | 1978 |
Hypotensive effect of [Sar1,Thr8]angiotensin II in spontaneously hypertensive sodium-depleted rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Desoxycorticosterone; Diet, Sodium-Restricted; Hypertension; Infusions, Parenteral; Rats; Renin; Saralasin; Sodium | 1978 |
[Radioimmunologic diagnosis and pathobiochemistry of the renin-angiotension-aldosterone system. Report of the workshop conference of the German Society for clinical chemistry on January 31 and February 1, 1975 in Bonn (author's transl)].
Topics: Aging; Aldosterone; Angiotensin II; Circadian Rhythm; Congresses as Topic; Diagnosis, Computer-Assisted; Germany, West; Humans; Renin; Specimen Handling | 1975 |
Control of aldosterone secretion in the spontaneously hypertensive rat.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Animals; Blood Pressure; Corticosterone; Hypertension; Kidney; Male; Pituitary Gland; Rats; Renin | 1975 |
Age as a determinant of renal sodium conservation in normal man.
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Glomerular Filtration Rate; Homeostasis; Humans; Kidney; Male; Middle Aged; Natriuresis; Regional Blood Flow; Renin; Sodium | 1976 |
Plasma renin activity as a function of age in two new strains of spontaneously hypertensive and normotensive rats.
Topics: Aging; Anesthesia, General; Angiotensin II; Animals; Body Weight; Ethyl Ethers; Hypertension; Male; Rats; Renin | 1976 |
Functional and morphological changes associated with the ageing of primary cultures of embryonic adrenal gland cells derived from the Pekin duck.
Topics: Actin Cytoskeleton; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aging; Angiotensin II; Animals; Cells, Cultured; Ducks; Endoplasmic Reticulum; Microscopy, Electron; Mitochondria; Time Factors | 1992 |
Effects of aging and hypertension on plasma angiotensin II and platelet angiotensin II receptor density.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Platelets; Humans; Hypertension; Middle Aged; Receptors, Angiotensin; Reference Values; Regression Analysis | 1992 |
Identification of three types of PDGF-A chain gene transcripts in rabbit vascular smooth muscle and their regulated expression during development and by angiotensin II.
Topics: Aging; Amino Acid Sequence; Angiotensin II; Animals; Aorta; Base Sequence; Cell Division; Cells, Cultured; Gene Expression Regulation; Gene Library; Gestational Age; Humans; Macromolecular Substances; Molecular Sequence Data; Muscle Development; Muscle, Smooth, Vascular; Oligonucleotide Probes; Platelet-Derived Growth Factor; Rabbits; RNA, Messenger; Sequence Homology, Nucleic Acid; Transcription, Genetic | 1992 |
Hormone responses of proximal Na(+)-H+ exchanger in spontaneously hypertensive rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Aging; Amiloride; Angiotensin II; Animals; Azepines; Blood Pressure; Carrier Proteins; Cyclic AMP; Dopamine; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Nephrons; Norepinephrine; Parathyroid Hormone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Sodium-Hydrogen Exchangers | 1991 |
Differential distribution of AT1 and AT2 angiotensin II receptor subtypes in the rat brain during development.
Topics: Aging; Angiotensin II; Animals; Autoradiography; Brain; Iodine Radioisotopes; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Angiotensin | 1991 |
Waning cardiovascular responses to adrenergic drugs in conscious ageing rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Epinephrine; Heart Rate; Isoproterenol; Male; Phenylephrine; Rats; Rats, Inbred Strains; Sympathomimetics | 1991 |
Ontogeny of renal renin release in spontaneously hypertensive rat and Wistar-Kyoto rat.
Topics: Aging; Angiotensin II; Animals; Hypertension; Isoproterenol; Kidney Cortex; Kidney Tubules, Proximal; Microvilli; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1991 |
Plasma immunoreactive endothelin-1 in experimental malignant hypertension.
Topics: Aging; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Caffeine; Creatinine; Desoxycorticosterone; Endothelins; Humans; Hypertension, Malignant; Hypertension, Renovascular; Kidney; Male; Phenylephrine; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery Obstruction; Renin; Systole | 1991 |
Angiotensin II-binding protein in adult and neonatal rat heart.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Heart; Myocardium; Organ Specificity; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Solubility | 1991 |
Characterization of AT2 angiotensin II receptors in rat anterior cerebral arteries.
Topics: Aging; Angiotensin II; Animals; Autoradiography; Binding, Competitive; Cerebral Arteries; Iodine Radioisotopes; Kinetics; Male; Muscle Development; Muscle, Smooth, Vascular; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin | 1991 |
Changes in expression of angiotensin receptor subtypes in the rat aorta during development.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Autoradiography; Binding, Competitive; Female; Fetus; Gestational Age; Iodine Radioisotopes; Kinetics; Male; Muscle Development; Muscle, Smooth, Vascular; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Angiotensin | 1991 |
Differential development of angiotensin II receptor subtypes in the rat brain.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Brain; Imidazoles; Kinetics; Losartan; Male; Oligopeptides; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles | 1991 |
Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall.
Topics: Aging; Angiotensin II; Animals; Arteries; Blood Pressure; Body Weight; Catheterization; Cell Division; DNA; Muscle, Smooth, Vascular; Rats; Reference Values | 1991 |
Angiotensin II induces secretion of plasminogen activator inhibitor 1 and a tissue metalloprotease inhibitor-related protein from rat brain astrocytes.
Topics: Aging; Amino Acid Sequence; Angiotensin II; Animals; Animals, Newborn; Astrocytes; Brain; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Glycoproteins; Kinetics; Methionine; Molecular Sequence Data; Molecular Weight; Nerve Tissue Proteins; Plasminogen Inactivators; Rats; Sequence Homology, Nucleic Acid; Sulfur Radioisotopes; Tissue Inhibitor of Metalloproteinases | 1991 |
Increased production of angiotensin II in the adrenal gland of stroke-prone spontaneously hypertensive rats with malignant hypertension.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin I; Angiotensin II; Animals; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Hypertension; Hypertension, Malignant; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin | 1991 |
[Local angiotensin in the myocardium of aging rats].
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Female; Myocardium; Rats; Rats, Inbred Strains | 1990 |
Effect of age on contractile response to angiotensin II in rat aorta.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains | 1990 |
Analysis of angiotensin II binding to human platelets: differences in young and old subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Angiotensin II; Arsenicals; Binding, Competitive; Blood Platelets; Chromatography, High Pressure Liquid; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Species Specificity; Time Factors | 1990 |
Cardiovascular correlates of predisposition to hypertension in pups of one kidney: one clip renal hypertensive dams.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Desoxycorticosterone; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Heart Rate; Hypertension, Renovascular; Male; Norepinephrine; Rats; Rats, Inbred Strains; Sodium, Dietary | 1990 |
Effect of age on response of secondary hypertension to specific treatment.
Topics: Adult; Aged; Aging; Angiotensin II; Blood Pressure; Humans; Hydrocortisone; Hypertension; Hypertension, Renovascular; Hypothyroidism; Middle Aged | 1990 |
Aldosterone production and hormone responsiveness in adrenal glomerulosa cells from cows of different ages.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aging; Aldosterone; Angiotensin II; Animals; Calcium; Cattle; Ion Channels; Phosphatidylinositols; Receptors, Angiotensin | 1987 |
Age dependence of the pressor sensitivity to noradrenaline and angiotensin II during calcium channel blockade in hypertensive patients.
Topics: Aged; Aged, 80 and over; Aging; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine | 1988 |
Effects of phorbol esters and a calcium ionophore on angiotensin II binding in rat brain synaptosomes.
Topics: Aging; Angiotensin II; Animals; Brain Stem; Calcimycin; Hypothalamus; Phorbol Esters; Protein Kinases; Rats; Rats, Inbred Strains; Synaptosomes | 1989 |
Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Ibuprofen; Indomethacin; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Reference Values; Sympathetic Nervous System; Synaptic Transmission | 1989 |
[The functional organization of autoregulation of local cerebral blood flow in spontaneously hypertensive rats in ontogeny].
Topics: Adenosine Triphosphate; Aging; Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Cerebrovascular Circulation; Electrodes, Implanted; Homeostasis; Hypertension; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY | 1989 |
Influence of age on glomerular binding of angiotensin II in normotensive and spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Female; Kidney Glomerulus; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin | 1989 |
The effect of neuropeptide Y on drinking in mice.
Topics: Aging; Angiotensin II; Animals; Arcuate Nucleus of Hypothalamus; Drinking Behavior; Glutamates; Injections, Intraventricular; Male; Mice; Neuropeptide Y; Sodium Glutamate | 1989 |
Renin-angiotensin modulation of sympathetic reflex function in essential hypertension and in the elderly.
Topics: Adult; Aged; Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Double-Blind Method; Enalapril; Heart Rate; Humans; Hypertension; Pyridazines; Random Allocation; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1988 |
Age-related changes in angiotensin II-stimulated proximal tubule fluid reabsorption in the spontaneously hypertensive rat.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Enalapril; Enalaprilat; Kidney Tubules, Proximal; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Water-Electrolyte Balance | 1988 |
Development of angiotensin II-sensitive OVLT neurons in SHR and WKY rats.
Topics: Action Potentials; Aging; Angiotensin II; Animals; Glutamates; Glutamic Acid; Hypertension; Hypothalamus; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1988 |
Beta-adrenergic receptors in rat myocardium during the development and reversal of hypertrophy and following chronic infusions of angiotensin II and epinephrine.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Dihydroalprenolol; Epinephrine; In Vitro Techniques; Male; Membranes; Myocardium; Nephrectomy; Nucleotidases; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Adrenergic, beta; Time Factors | 1985 |
[Age-related and regional changes in angiotensin-converting and kinin-degrading activity in the brain of aggressive rats].
Topics: Aggression; Aging; Angiotensin II; Animals; Bradykinin; Brain; Kinins; Male; Mice; Peptidyl-Dipeptidase A; Rats; Reaction Time | 1987 |
Increased angiotensin II receptor binding with age in isolated rat glomeruli.
Topics: Aging; Angiotensin II; Animals; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1988 |
Thirst-induced anorexias and the ontogeny of thirst in the rat.
Topics: Aging; Angiotensin II; Animals; Appetite; Drinking; Female; Hunger; Male; Rats; Rats, Inbred Strains; Renin; Taste; Thirst; Water-Electrolyte Balance | 1988 |
Evidence for functional communication between folliculo-stellate cells and hormone-secreting cells in perifused anterior pituitary cell aggregates.
Topics: Aging; Angiotensin II; Animals; Cell Aggregation; Cell Communication; Female; Gonadotropin-Releasing Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Kinetics; Male; Microscopy, Electron; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; S100 Proteins | 1987 |
Angiotensin II vascular receptors in fetal and neonatal rats.
Topics: Aging; Angiotensin II; Animals; Animals, Newborn; Autoradiography; Female; Heart; Myocardium; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Angiotensin | 1988 |
Age-related changes in the response to vasoconstrictor and dilator agents in isolated beagle coronary arteries.
Topics: Acetylcholine; Adenosine; Aging; Angiotensin II; Animals; Coronary Vessels; Dogs; Epoprostenol; Female; Histamine; In Vitro Techniques; Male; Serotonin; Vasoconstrictor Agents; Vasodilator Agents | 1987 |
Angiotensin II receptors in testes.
Topics: Aging; Angiotensin II; Animals; Autoradiography; Iodine Radioisotopes; Kinetics; Leydig Cells; Male; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Testis | 1988 |
Effect of age on vascular prostaglandin production in male and female rats.
Topics: Aging; Angiotensin II; Animals; Aorta, Thoracic; Blood Vessels; Female; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Prostaglandins; Rats; Rats, Inbred Strains | 1986 |
Neuroeffector function in mesenteric arteries isolated from beagles of different ages.
Topics: Aging; Angiotensin II; Animals; Dogs; Female; Male; Mesenteric Arteries; Muscle Contraction; Norepinephrine; Potassium; Prazosin; Serotonin; Vasoconstriction; Yohimbine | 1987 |
[Changes in reactivity of the renin-angiotensin-aldosterone system in old age as a risk factor in the development of hypertension].
Topics: Adult; Aged; Aging; Aldosterone; Angiotensin II; Homeostasis; Humans; Hypertension; Hypothalamo-Hypophyseal System; Middle Aged; Pituitary-Adrenal System; Renin; Renin-Angiotensin System; Risk; Sympathetic Nervous System | 1985 |
Reactivity of small vessels from mature to senescent female rabbits.
Topics: Aging; Angiotensin II; Animals; Ear; Female; Femoral Artery; Histamine; Muscle Contraction; Muscle, Smooth, Vascular; Muscles; Norepinephrine; Propranolol; Rabbits | 1985 |
Changes in the carotid pulse which occur with age and hypertension.
Topics: Adult; Aging; Amyl Nitrite; Angiotensin II; Arteriosclerosis; Blood Pressure; Carotid Arteries; Electrocardiography; Heart Rate; Hemodynamics; Humans; Hypertension; Isoproterenol; Methoxamine; Phonocardiography; Pulse; Trimethaphan | 1966 |
Renin activity of the kidney in the spontaneously hypertensive rat.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Femoral Artery; Femoral Vein; Hypertension; Kidney; Nephrectomy; Rats; Renal Artery; Renal Veins; Renin | 1966 |
Action of angiotensin II upon renal vascular resistance.
Topics: Aging; Angiotensin II; Animals; Epinephrine; Female; Kidney; Male; Muscle, Smooth; Perfusion; Pressure; Rabbits; Sex; Vascular Resistance; Vasopressins | 1967 |
Influence of stress, adrenalectomy and age on the stimulation in vitro of rat kidney ATPase by angiotensin.
Topics: Adenosine Triphosphatases; Adrenal Glands; Adrenalectomy; Age Factors; Aging; Aldosterone; Anesthesia, Inhalation; Angiotensin II; Animals; Animals, Newborn; In Vitro Techniques; Kidney; Male; Norepinephrine; Rats; Stimulation, Chemical; Stress, Physiological | 1970 |
Age-related changes of cardiac performance in male rats.
Topics: Aging; Angiotensin II; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Body Weight; Cardiac Output; Dextrans; Heart; Heart Atria; Heart Rate; Heart Ventricles; Male; Organ Size; Rats; Rats, Inbred Strains; Stress, Physiological; Time Factors; Vascular Resistance | 1972 |
Syndrome of hyporeninemic hypoaldosteronism and hyperkalemia in renal disease.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Humans; Hydrocortisone; Hyperkalemia; Juxtaglomerular Apparatus; Kidney Failure, Chronic; Male; Middle Aged; Posture; Potassium; Renin; Sodium; Syndrome | 1973 |
[Aging of the bronchial tree and the bronchial vascular system. 2. Changes in the bronchial vascular system tone due to aging].
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Blood Vessels; Bronchi; Bronchial Arteries; Dogs; Epinephrine; Muscle Tonus; Serotonin; Stimulation, Chemical | 1972 |
Senescence and the renal vasculature in normal man.
Topics: Acetylcholine; Adolescent; Adult; Aged; Aging; Angiotensin II; Blood Flow Velocity; Humans; Kidney; Middle Aged; Radioisotopes; Regional Blood Flow; Sodium; Xenon | 1974 |
Baro- and chemoreceptor mechanisms in haemorrhage.
Topics: Aging; Angiotensin II; Animals; Arteries; Benzyl Compounds; Blood Pressure; Blood Volume; Cats; Chemoreceptor Cells; Denervation; Guanidines; Hematocrit; Hemoglobins; Hemorrhage; Nephrectomy; Pressoreceptors; Rabbits; Renin; Sympathetic Nervous System | 1972 |
Ontogeny of thirst in the rat: effects of hypertonic saline polyethylene glycol, and vena cava ligation.
Topics: Aging; Angiotensin II; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking; Female; Hypertonic Solutions; Ligation; Male; Polyethylene Glycols; Rats; Renin; Sodium Chloride; Thirst; Venae Cavae; Water-Electrolyte Balance | 1974 |