Page last updated: 2024-09-03

angiotensin ii, des-phe(8)- and Innate Inflammatory Response

angiotensin ii, des-phe(8)- has been researched along with Innate Inflammatory Response in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (3.92)29.6817
2010's36 (70.59)24.3611
2020's13 (25.49)2.80

Authors

AuthorsStudies
Campagnole-Santos, MJ; Campolina-Silva, GH; Cramer, A; Galvão, I; Grossi, LC; Lima, KM; Miranda, TC; Negreiros-Lima, GL; Pinho, V; Santos, RA; Sousa, LP; Souza, JA; Sugimoto, MA; Tavares, LP; Teixeira, LC; Teixeira, MM; Vago, JP; Valiate, BV; Zaidan, I1
Azuelos, I; Baglole, CJ; Eidelman, DH; Haidar, Z; Huang, MJ; Morganstein, T; Trivlidis, J1
Kuruppu, S; Rajapakse, NW; Tran, S1
Melo, EM; Sousa, LP; Tavares, LP; Teixeira, MM1
Banerjee, A; Baptista, LC; Buchanan, T; Buford, TW; Carter, CS; Graham, ZA; Hernandez, AR; Li, Q; Sun, Y; Verma, A; Yang, Y; Zumbro, EL1
Liu, X; Xu, J; Yu, Z1
Li, X; Li, Y; Lou, A; Su, L; Tong, H; Zhang, M; Zhu, X1
Pinho, V; Sousa, LP; Teixeira, MM1
Franco, R; Labandeira-García, JL; Navarro, G; Rivas-Santisteban, R; Rodríguez-Pérez, AI; Serrano-Marín, J1
Antunes-Rodrigues, J; Batalhão, ME; Bendhack, LM; Capellari Carnio, E; de Lima Faim, F; Lacchini, R; Passaglia, P; Stabile, AM1
Chen, M; Guo, Y; Hong, L; Jiang, S; Liu, S; Pan, R; Shi, J; Wang, Q; Yuan, X1
Cantero-Navarro, E; Fernández-Fernández, B; Ortiz, A; Ramos, AM; Rayego-Mateos, S; Rodrigues-Diez, RR; Ruiz-Ortega, M; Sánchez-Niño, MD; Sanz, AB1
An, X; Fu, M; He, X; Li, C; Niu, L; Tian, J; Wang, Q; Xu, H1
Gao, W; Hu, W; Miao, J; Sun, L; Xu, Z1
Boehler, T; Fiedler, R; Girndt, M; Hulko, M; Martus, P; Schindler, R; Storr, M; Trojanowicz, B; Ulrich, C; Werner, K; Willy, K; Zickler, D1
Chi, C; Cui, L; Hou, F; Li, C; Liu, R; Liu, X; Wang, Y; Wen, Y; Yin, C; Yu, X1
Greenberg, G; Hamias, R; Rudich, A; Szendro, G; Wolak, T1
Chen, WQ; Cheng, J; Ji, XP; Mao, Y; Qiao, L; Tie, YY; Xu, QB; Xu, YY; Zhai, CG; Zhang, C; Zhang, Y1
Chen, WY; Li, ZX; Liang, ML; Shi, H; Sun, XT; Wang, X; Yang, YY; Yang, ZS; Zeng, WT1
Cui, L; Liu, R; Wang, G; Wang, Y; Xiao, H; Yin, C1
Chen, J; Chen, W; Feng, J; Li, C; Wang, Z; Xu, Q; Xu, Z; Zhang, J; Zhang, W; Zhang, Y; Zhen, Y1
Abd El-Rahman, SS; Abdelkader, NF; Emara, M; Kamel, AS; Khattab, MM; Zaki, HF1
Gao, Q; Jiang, T; Ou, Z; Shi, JQ; Wang, QG; Wu, L; Xue, LJ; Xue, X; Yang, Y; Zhang, YD1
Bartlett, MJ; Doyle, KP; Falk, T; Hay, M; Heien, ML; Konhilas, JP; Largent-Milnes, TM; Polt, R; Rodgers, K; Vanderah, TW1
Arroja, MMC; Holmes, WM; McCabe, C; Nicklin, SA; Reid, E; Roy, LA; Vallatos, AV; Work, LM1
Crespo, TS; Freitas, DF; Lelis, DF; Machado, AS; Santos, SHS1
da Silva Filha, R; de Almeida, TCS; de Andrade De Maria, ML; Ferreira, AJ; Kangussu, LM; Prestes, TRR; Silva, ACSE; Vieira, MAR1
Alvarez-Leite, JI; Andrade, JM; Feltenberger, JD; Fernandes, LR; Santos, RA; Santos, SH; Sinisterra, RD; Sousa, FB1
Bader, M; Barroso, LC; Coelho, FM; Costa, VV; Oliveira, ML; Queiroz-Junior, CM; Santos, RA; Silva, AC; Silva, TA; Silveira, KD; Sousa, LF; Teixeira, MM; Vieira, AT1
Andrade, JM; Barros, LO; Campagnole-Santos, MJ; de Paula, AM; dos Santos, RA; Feltenberger, JD; Filho, AB; Guimarães, AL; Paraíso, A; Qureshi, M; Santos, SH; Sinisterra, RD; Sousa, FB1
Gallagher, PE; Kooshki, M; Metheny-Barlow, LJ; Moore, ED; Robbins, ME1
Abo Alrob, O; Altamimi, T; Basu, R; Desaulniers, J; Kassiri, Z; Lopaschuk, GD; Mori, J; Oudit, GY; Patel, VB; Wagg, CS1
Bertolotto, M; Caffa, I; Capettini, LA; Costa-Fraga, FP; da Silva, RF; Dallegri, F; De Sousa, FB; Fraga-Silva, RA; Galan, K; Lenglet, S; Mach, F; Montecucco, F; Nencioni, A; Palombo, D; Pane, B; Pelli, G; Pende, A; Santos, RA; Savergnini, SQ; Sinisterra, RD; Soncini, D; Spinella, G; Stergiopulos, N1
Acuña, MJ; Brandan, E; Cabrera, D; Rebolledo, D; Riquelme, C; Santos, RA; Torrejón, J1
Li, C; Li, Y; Li, Z; Liu, M; Sun, X; Wang, Y; Wu, H; Xu, D1
Bhatia, M; Chambers, S; Gaddam, RR1
Chen, X; Dong, B; Dong, XF; Hao, QQ; Li, SY; Tengbeh, AF; Yu, QT; Zhang, Y; Zhang, YH; Zhou, XM1
Basu, R; Das, SK; Grant, MB; Lopaschuk, GD; McLean, BA; Mori, J; Oudit, GY; Parajuli, N; Patel, VB; Penninger, JM; Ramprasath, T1
Akashi, AP; Amaral, SL; Becari, C; Colombini-Ishikiriama, BL; Didier, DN; Dionísio, TJ; Faria, FA; Figueiredo, CM; Garlet, GP; Greene, AS; Lima, MC; Maciel, RP; Matus, I; Morandini, AC; Oliveira, EB; Rodini, CO; Salgado, MC; Santos, CF; Sipert, CR; Souza, GP1
Chen, LJ; Gao, PJ; Jin, HY; Oudit, GY; Song, B; Xu, R; Xu, YL; Zhang, ZZ; Zhong, JC; Zhu, DL1
Huang, W; Luo, L; Ren, F; Tang, L; Yan, R; Zhang, L; Zheng, Y1
Demkow, U; Radkowski, M; Winklewski, PJ1
Hu, K; Kang, J; Li, Y; Lu, W; Tang, S; Xu, L; Yu, S; Zhou, X1
Barnes, CA; Constantopoulos, E; Hay, M; Konhilas, J; Samareh-Jahani, F; Uprety, AR; Vanderah, TW1
Hu, K; Kang, J; Lu, W; Tang, S; Xu, L; Yu, S; Zhou, X1
de Bruin, R; Egido, J; Esteban, V; Heringer-Walther, S; Mezzano, S; Ruiz-Ortega, M; Schultheiss, HP; Sterner-Kock, A; van den Engel, S; Walther, T; Wang, Y1
Gurusamy, N; Kodama, M; Lakshmanan, AP; Ma, M; Nagata, M; Sukumaran, V; Suzuki, K; Takagi, R; Veeraveedu, PT; Watanabe, K; Yamaguchi, K1
Alvarez-Leite, JI; Bader, M; Campagnole-Santos, MJ; de Paula, AM; Fernandes, LR; Guimarães, AL; Pereira, CS; Santos, RA; Santos, SH1
Gao, L; Guo, J; Jiang, T; Lu, J; Wang, Y; Zhang, Y1
Hu, X; Tian, F; Wang, L; Zhang, W1
Lin, CS; Pan, CH1

Reviews

9 review(s) available for angiotensin ii, des-phe(8)- and Innate Inflammatory Response

ArticleYear
Involvement of the ACE2/Ang-(1-7)/MasR Axis in Pulmonary Fibrosis: Implications for COVID-19.
    International journal of molecular sciences, 2021, Nov-30, Volume: 22, Issue:23

    Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Cannabis; Cigarette Smoking; COVID-19; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Inflammation; Lung; Pandemics; Peptide Fragments; Proto-Oncogene Mas; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Risk Factors; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2021
Chronic Renin-Angiotensin System Activation Induced Neuroinflammation: Common Mechanisms Underlying Hypertension and Dementia?
    Journal of Alzheimer's disease : JAD, 2022, Volume: 85, Issue:3

    Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Brain; Cytokines; Dementia, Vascular; Humans; Hypertension; Inflammation; Peptide Fragments; Renin-Angiotensin System

2022
Pro-resolving therapies as potential adjunct treatment for infectious diseases: Evidence from studies with annexin A1 and angiotensin-(1-7).
    Seminars in immunology, 2022, Volume: 59

    Topics: Angiotensin I; Annexin A1; Communicable Diseases; Humans; Inflammation; Inflammation Mediators

2022
Harnessing inflammation resolving-based therapeutic agents to treat pulmonary viral infections: What can the future offer to COVID-19?
    British journal of pharmacology, 2020, Volume: 177, Issue:17

    Topics: Acetates; Angiotensin I; Animals; Annexin A1; Anti-Inflammatory Agents; COVID-19; COVID-19 Drug Treatment; Disease Models, Animal; Docosahexaenoic Acids; Humans; Hydrogen Peroxide; Inflammation; Inflammation Mediators; Mice; Orthomyxoviridae Infections; Oxidants; Peptide Fragments; Peptides; Phosphodiesterase 4 Inhibitors; Pneumonia, Viral; Rolipram; Vasodilator Agents

2020
SARS-CoV-2 as a Factor to Disbalance the Renin-Angiotensin System: A Suspect in the Case of Exacerbated IL-6 Production.
    Journal of immunology (Baltimore, Md. : 1950), 2020, 09-01, Volume: 205, Issue:5

    Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Inflammation; Interleukin-6; Macrophages; Pandemics; Peptide Fragments; Peptidyl-Dipeptidase A; Pneumonia, Viral; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2

2020
Renin-angiotensin system and inflammation update.
    Molecular and cellular endocrinology, 2021, 06-01, Volume: 529

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autoimmunity; Blood Pressure; Gene Expression Regulation; Humans; Inflammation; Kidney; Klotho Proteins; Peptide Fragments; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; T-Lymphocytes; Water-Electrolyte Balance

2021
Angiotensin-(1-7), Adipokines and Inflammation.
    Metabolism: clinical and experimental, 2019, Volume: 95

    Topics: Adipokines; Adipose Tissue; Angiotensin I; Animals; Humans; Inflammation; Peptide Fragments; Proto-Oncogene Mas

2019
ACE and ACE2 in inflammation: a tale of two enzymes.
    Inflammation & allergy drug targets, 2014, Volume: 13, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Inflammation; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System

2014
Regulatory mechanisms of atrial fibrotic remodeling in atrial fibrillation.
    Cellular and molecular life sciences : CMLS, 2008, Volume: 65, Issue:10

    Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Atrial Fibrillation; Endomyocardial Fibrosis; Heart Atria; Humans; Inflammation; Matrix Metalloproteinases; Models, Biological; Oxidative Stress; Peptide Fragments; ras GTPase-Activating Proteins; Signal Transduction; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta1; Ventricular Remodeling

2008

Trials

1 trial(s) available for angiotensin ii, des-phe(8)- and Innate Inflammatory Response

ArticleYear
Modulation of leucocytic angiotensin-converting enzymes expression in patients maintained on high-permeable haemodialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018, Jan-01, Volume: 33, Issue:1

    Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Biomarkers; Cross-Over Studies; Dialysis Solutions; Double-Blind Method; Humans; Inflammation; Inflammation Mediators; Monocytes; Peptide Fragments; Peptidyl-Dipeptidase A; Pilot Projects; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Dialysis

2018

Other Studies

41 other study(ies) available for angiotensin ii, des-phe(8)- and Innate Inflammatory Response

ArticleYear
Angiotensin-(1-7)/MasR axis promotes migration of monocytes/macrophages with a regulatory phenotype to perform phagocytosis and efferocytosis.
    JCI insight, 2022, 01-11, Volume: 7, Issue:1

    Topics: Angiotensin I; Animals; Cells, Cultured; Disease Models, Animal; Humans; Inflammation; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Monocytes; Peptide Fragments; Peritonitis; Phagocytosis; Phenotype; Proto-Oncogene Mas; Receptors, CCR2

2022
Multiomics profiling of the impact of an angiotensin (1-7)-expressing probiotic combined with exercise training in aged male rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2023, 05-01, Volume: 134, Issue:5

    Topics: Animals; Inflammation; Male; Multiomics; Physical Conditioning, Animal; Rats; Renin-Angiotensin System

2023
Angiotensin-(1-7) suppresses airway inflammation and airway remodeling via inhibiting ATG5 in allergic asthma.
    BMC pulmonary medicine, 2023, Nov-02, Volume: 23, Issue:1

    Topics: Airway Remodeling; Animals; Asthma; Autophagy-Related Protein 5; Disease Models, Animal; DNA, Complementary; Fibrosis; Humans; Inflammation; Interleukin-13; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; RNA, Small Interfering; Transforming Growth Factor beta1

2023
AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway.
    BioMed research international, 2019, Volume: 2019

    Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Heat Stroke; Hepatocytes; Humans; Imidazoles; Inflammasomes; Inflammation; Interleukin-1beta; Liver; Liver Cirrhosis; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Prospective Studies; Pyroptosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction

2019
Central Administration of Angiotensin-(1-7) Improves Vasopressin Impairment and Hypotensive Response in Experimental Endotoxemia.
    Cells, 2021, 01-08, Volume: 10, Issue:1

    Topics: Angiotensin I; Animals; Endotoxemia; Gene Expression Regulation; Hypotension; Inflammation; Lactic Acid; Lipopolysaccharides; Male; Osmolar Concentration; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Wistar; Receptors, G-Protein-Coupled; Sodium; Vasopressins

2021
Mas receptor activation attenuates allergic airway inflammation via inhibiting JNK/CCL2-induced macrophage recruitment.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 137

    Topics: Acute Disease; Angiotensin I; Animals; Asthma; Chemokine CCL2; Cytokines; Imidazoles; Inflammation; Macrophage Activation; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Ovalbumin; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Respiratory System

2021
Angiotensin-(1-7) protects against sepsis-associated left ventricular dysfunction induced by lipopolysaccharide.
    Peptides, 2021, Volume: 144

    Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Cardiotonic Agents; Cells, Cultured; Inflammation; Lipopolysaccharides; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Nerve Tissue Proteins; Peptide Fragments; Proto-Oncogene Mas; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Sepsis; Ventricular Dysfunction, Left

2021
Alamandine, a derivative of angiotensin-(1-7), alleviates sepsis-associated renal inflammation and apoptosis by inhibiting the PI3K/Ak and MAPK pathways.
    Peptides, 2021, Volume: 146

    Topics: Angiotensin I; Animals; Apoptosis; Cell Line; Dose-Response Relationship, Drug; Humans; Inflammation; Kidney; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Peptide Fragments; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Sepsis; Signal Transduction

2021
Angiotensin-converting enzyme 2-angiotensin (1-7)-Mas axis prevents pancreatic acinar cell inflammatory response via inhibition of the p38 mitogen-activated protein kinase/nuclear factor-κB pathway.
    International journal of molecular medicine, 2018, Volume: 41, Issue:1

    Topics: Acinar Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Imidazoles; Inflammation; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pancreas; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction

2018
Angiotensin 1-7, but not the thrombin-cleaved osteopontin C-terminal fragment, attenuates osteopontin-mediated macrophage-induced endothelial-cell inflammation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2018, Volume: 67, Issue:3

    Topics: Angiotensin I; Cells, Cultured; Endothelial Cells; Humans; I-kappa B Proteins; Inflammation; Intercellular Adhesion Molecule-1; Macrophages; NF-kappa B; Osteopontin; Peptide Fragments; U937 Cells; Vascular Cell Adhesion Molecule-1

2018
DKK3 overexpression attenuates cardiac hypertrophy and fibrosis in an angiotensin-perfused animal model by regulating the ADAM17/ACE2 and GSK-3β/β-catenin pathways.
    Journal of molecular and cellular cardiology, 2018, Volume: 114

    Topics: ADAM17 Protein; Adaptor Proteins, Signal Transducing; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Apoptosis; beta Catenin; Cardiomegaly; Cell Proliferation; Disease Models, Animal; Fibroblasts; Fibrosis; Glycogen Synthase Kinase 3 beta; Inflammation; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinases; Mice, Inbred C57BL; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Phosphorylation; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1

2018
Protective effect of angiotensin-(1-7) against hyperglycaemia-induced injury in H9c2 cardiomyoblast cells via the PI3K̸Akt signaling pathway.
    International journal of molecular medicine, 2018, Volume: 41, Issue:3

    Topics: Angiotensin I; Animals; Apoptosis; Cardiotonic Agents; Caspases; Cell Line; Cell Survival; Cytoprotection; Glucose; Hyperglycemia; Inflammation; Membrane Potential, Mitochondrial; Myocytes, Cardiac; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction

2018
Angiotensin 1-7 ameliorates caerulein-induced inflammation in pancreatic acinar cells by downregulating Toll-like receptor 4/nuclear factor-κB expression.
    Molecular medicine reports, 2018, Volume: 17, Issue:3

    Topics: Acinar Cells; Angiotensin I; Angiotensin II; Animals; Cell Line; Ceruletide; Down-Regulation; Inflammation; Interleukin-10; Interleukin-6; Microscopy, Fluorescence; NF-kappa B; Peptide Fragments; Rats; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2018
Ang-(1-7) protects HUVECs from high glucose-induced injury and inflammation via inhibition of the JAK2/STAT3 pathway.
    International journal of molecular medicine, 2018, Volume: 41, Issue:5

    Topics: Angiotensin I; Cell Survival; Cytoprotection; Endothelial Cells; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Janus Kinase 2; Oxidative Stress; Peptide Fragments; Protective Agents; Signal Transduction; STAT3 Transcription Factor

2018
Stimulation of ACE2/ANG(1-7)/Mas Axis by Diminazene Ameliorates Alzheimer's Disease in the D-Galactose-Ovariectomized Rat Model: Role of PI3K/Akt Pathway.
    Molecular neurobiology, 2018, Volume: 55, Issue:10

    Topics: Alzheimer Disease; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Cell Survival; Cognition; Diminazene; Female; Galactose; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Inflammation; Maze Learning; Nerve Growth Factors; Neuronal Plasticity; Organelle Biogenesis; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Glutamate; Receptors, Nicotinic; Signal Transduction; tau Proteins

2018
AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation.
    Aging, 2018, 04-17, Volume: 10, Issue:4

    Topics: Aging; Angiotensin I; Animals; Brain; Imidazoles; Inflammation; Mice; Microglia; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled

2018
A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction.
    The Journal of pharmacology and experimental therapeutics, 2019, Volume: 369, Issue:1

    Topics: Angiotensin I; Animals; Behavior, Animal; Biomarkers; Brain; Cognitive Dysfunction; Dementia, Vascular; Electrocardiography; Glycosylation; Half-Life; Heart Failure; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Maze Learning; Memory; Mice; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Spatial Memory; Ventricular Remodeling

2019
Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion.
    Scientific reports, 2019, 02-28, Volume: 9, Issue:1

    Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Blood-Brain Barrier; Contrast Media; Disease Models, Animal; Gene Expression Regulation; Humans; Infarction, Middle Cerebral Artery; Inflammation; Magnetic Resonance Imaging; Microglia; Middle Cerebral Artery; NADPH Oxidase 1; Neuroprotective Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Rats; Renin-Angiotensin System; Reperfusion; RNA, Messenger; Stroke

2019
Beneficial Effects of the Angiotensin-Converting Enzyme 2 Activator Dize in Renovascular Hypertension.
    Protein and peptide letters, 2019, Volume: 26, Issue:7

    Topics: Acetylglucosaminidase; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Cytokines; Diminazene; Enzyme Activators; Hypertension, Renovascular; Inflammation; Kidney; Male; Nitric Oxide; Peptide Fragments; Peptidyl-Dipeptidase A; Peroxidase; Rats, Wistar; Renin-Angiotensin System

2019
Oral Angiotensin-(1-7) prevented obesity and hepatic inflammation by inhibition of resistin/TLR4/MAPK/NF-κB in rats fed with high-fat diet.
    Peptides, 2013, Volume: 46

    Topics: Angiotensin I; Animals; Blood Glucose; Cholesterol; Diet, High-Fat; Glucose Tolerance Test; Inflammation; Insulin; Insulin Resistance; Lipoproteins, HDL; Liver; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Obesity; Peptide Fragments; Rats; Rats, Sprague-Dawley; Resistin; Toll-Like Receptor 4; Triglycerides

2013
Mechanisms of the anti-inflammatory actions of the angiotensin type 1 receptor antagonist losartan in experimental models of arthritis.
    Peptides, 2013, Volume: 46

    Topics: Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Adhesion; Chemokine CXCL1; Disease Models, Animal; Female; Hyperalgesia; Inflammation; Interleukin-1beta; Leukocyte Rolling; Losartan; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha

2013
Oral formulation of angiotensin-(1-7) improves lipid metabolism and prevents high-fat diet-induced hepatic steatosis and inflammation in mice.
    Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:2

    Topics: Administration, Oral; Angiotensin I; Animals; Chemistry, Pharmaceutical; Diet, High-Fat; Fatty Liver; Inflammation; Interleukin-6; Lipid Metabolism; Male; Mice; Peptide Fragments; Sterol Regulatory Element Binding Protein 1; Tumor Necrosis Factor-alpha

2013
Angiotensin-(1-7) prevents radiation-induced inflammation in rat primary astrocytes through regulation of MAP kinase signaling.
    Free radical biology & medicine, 2013, Volume: 65

    Topics: Angiotensin I; Animals; Astrocytes; Cells, Cultured; Drug Evaluation, Preclinical; Dual Specificity Phosphatase 1; Inflammation; MAP Kinase Signaling System; Peptide Fragments; Primary Cell Culture; Radiation-Protective Agents; Rats

2013
Angiotensin 1-7 ameliorates diabetic cardiomyopathy and diastolic dysfunction in db/db mice by reducing lipotoxicity and inflammation.
    Circulation. Heart failure, 2014, Mar-01, Volume: 7, Issue:2

    Topics: Angiotensin I; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Diastole; Echocardiography, Doppler; Follow-Up Studies; Inflammation; Insulin Resistance; Lipids; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Vasodilator Agents; Ventricular Dysfunction, Left; Ventricular Function; Ventricular Pressure

2014
Treatment with Angiotensin-(1-7) reduces inflammation in carotid atherosclerotic plaques.
    Thrombosis and haemostasis, 2014, Apr-01, Volume: 111, Issue:4

    Topics: Administration, Oral; Angiotensin I; Animals; Anti-Inflammatory Agents; Apolipoproteins E; Carotid Arteries; Case-Control Studies; Disease Models, Animal; Humans; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Plaque, Atherosclerotic

2014
ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Cytoskeletal Proteins; Fibrosis; Humans; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Peptide Fragments; Peptidyl-Dipeptidase A

2014
Tanshinone IIA attenuates bleomycin-induced pulmonary fibrosis via modulating angiotensin-converting enzyme 2/ angiotensin-(1-7) axis in rats.
    International journal of medical sciences, 2014, Volume: 11, Issue:6

    Topics: Abietanes; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Bleomycin; Humans; Inflammation; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Fibrosis; Rats; Transforming Growth Factor beta

2014
ACE2 and Ang-(1-7) protect endothelial cell function and prevent early atherosclerosis by inhibiting inflammatory response.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2015, Volume: 64, Issue:3-4

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Atherosclerosis; Cell Adhesion; Cell Movement; Chemokine CCL2; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Gene Transfer Techniques; Humans; In Vitro Techniques; Inflammation; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Vascular Cell Adhesion Molecule-1

2015
ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity.
    Diabetes, 2016, Volume: 65, Issue:1

    Topics: Adiponectin; Adipose Tissue; AMP-Activated Protein Kinases; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Blotting, Western; Diet, High-Fat; Enzyme-Linked Immunosorbent Assay; Glucose Intolerance; Heart; Heart Failure; Humans; Inflammation; Insulin Resistance; Macrophages; Mice; Mice, Knockout; Myocardium; Obesity; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Pericardium; Phosphorylation; Real-Time Polymerase Chain Reaction; Stroke Volume; Tumor Necrosis Factor-alpha; Vasodilator Agents; Weight Gain

2016
Functional Local Renin-Angiotensin System in Human and Rat Periodontal Tissue.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adult; Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Female; Gingiva; Humans; Inflammation; Male; Middle Aged; Peptide Fragments; Periodontitis; Periodontium; Rats, Wistar; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Young Adult

2015
Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.
    Journal of translational medicine, 2015, Aug-06, Volume: 13

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Gene Deletion; Humans; Inflammation; Kidney; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Signal Transduction; Superoxides; Tumor Necrosis Factor-alpha

2015
Anti-Inflammatory Effects of Ang-(1-7) in Ameliorating HFD-Induced Renal Injury through LDLr-SREBP2-SCAP Pathway.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Acute Kidney Injury; Angiotensin I; Animals; Anti-Inflammatory Agents; Diet, High-Fat; Dyslipidemias; Inflammation; Kidney; Lipid Metabolism; Male; Mice, Inbred C57BL; Peptide Fragments; Receptors, LDL; Signal Transduction; Sterol Regulatory Element Binding Protein 2

2015
Neuroinflammatory mechanisms of hypertension: potential therapeutic implications.
    Current opinion in nephrology and hypertension, 2016, Volume: 25, Issue:5

    Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cytokines; Humans; Hypertension; Inflammation; Lipopolysaccharides; Microglia; NF-kappa B; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Renin; Toll-Like Receptor 4

2016
Angiotensin-(1-7) inhibits inflammation and oxidative stress to relieve lung injury induced by chronic intermittent hypoxia in rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2016, Sep-01, Volume: 49, Issue:10

    Topics: Angiotensin I; Animals; Blotting, Western; Cytokines; Enzyme-Linked Immunosorbent Assay; Hypoxia; Immunohistochemistry; Inflammation; Lung; Lung Injury; Male; Malondialdehyde; Oxidative Stress; Peptide Fragments; Protective Agents; Random Allocation; Rats, Sprague-Dawley; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Sleep Apnea, Obstructive; Vasodilator Agents

2016
Cognitive impairment in heart failure: A protective role for angiotensin-(1-7).
    Behavioral neuroscience, 2017, Volume: 131, Issue:1

    Topics: Angiotensin I; Animals; Cognitive Dysfunction; Disease Models, Animal; Heart Failure; Inflammation; Male; Maze Learning; Mice; Mice, Inbred C57BL; Myocardial Infarction; Peptide Fragments; Ventricular Remodeling; Visual Acuity

2017
Angiotensin-(1-7) relieved renal injury induced by chronic intermittent hypoxia in rats by reducing inflammation, oxidative stress and fibrosis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Jan-09, Volume: 50, Issue:1

    Topics: Acute Kidney Injury; Angiotensin I; Animals; Disease Models, Animal; Inflammation; Interleukin-6; Kidney; Male; Oxidative Stress; Peptide Fragments; Rats; Rats, Sprague-Dawley

2017
Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation.
    PloS one, 2009, Volume: 4, Issue:4

    Topics: Angiotensin I; Animals; Antihypertensive Agents; Cytokines; Inflammation; Kidney Diseases; Mice; Mice, Knockout; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Reperfusion Injury

2009
Olmesartan attenuates the development of heart failure after experimental autoimmune myocarditis in rats through the modulation of ANG 1-7 mas receptor.
    Molecular and cellular endocrinology, 2012, Apr-04, Volume: 351, Issue:2

    Topics: Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Autoimmune Diseases; Cardiotonic Agents; Endoplasmic Reticulum Stress; Heart Failure; Imidazoles; Inflammation; JNK Mitogen-Activated Protein Kinases; Membrane Glycoproteins; Myocarditis; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Phosphoproteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Receptors, Interleukin-1; RNA, Messenger; Tetrazoles

2012
Increased circulating angiotensin-(1-7) protects white adipose tissue against development of a proinflammatory state stimulated by a high-fat diet.
    Regulatory peptides, 2012, Oct-10, Volume: 178, Issue:1-3

    Topics: Adipokines; Adiposity; Angiotensin I; Animals; Blood Glucose; Cholesterol, HDL; Diet, High-Fat; Epididymis; Inflammation; Inflammation Mediators; Interleukin-1beta; Intra-Abdominal Fat; Male; Obesity; Oxidative Stress; Peptide Fragments; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Tumor Necrosis Factor-alpha

2012
Suppressing inflammation by inhibiting the NF-κB pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia.
    British journal of pharmacology, 2012, Volume: 167, Issue:7

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Inflammatory Agents; Behavior, Animal; Cerebrovascular Circulation; Imidazoles; Infarction, Middle Cerebral Artery; Inflammation; Male; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled

2012
Angiotensin (1-7) ameliorates angiotensin II-induced inflammation by inhibiting LOX-1 expression.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2013, Volume: 62, Issue:2

    Topics: Angiotensin I; Angiotensin II; Animals; Cell Adhesion; Chemokine CCL2; DNA; Endothelial Cells; Female; Humans; Inflammation; Male; NF-kappa B; Peptide Fragments; Rabbits; Scavenger Receptors, Class E; Vascular Cell Adhesion Molecule-1

2013