Page last updated: 2024-11-07

androsterone and Premenstrual Dysphoric Disorder

androsterone has been researched along with Premenstrual Dysphoric Disorder in 1 studies

Premenstrual Dysphoric Disorder: A condition in which a woman suffers from severe depression, irritability, and tension before MENSTRUATION. Premenstrual dysphoric disorder (PMDD) may involve a wide range of physical or emotional symptoms, which are more severe and debilitating than those seen with premenstrual syndrome (PMS), and which include at least one mood-related symptom. Symptoms usually stop when, or shortly after, menstruation begins.

Research Excerpts

ExcerptRelevanceReference
" To test this hypothesis, we stabilized neurosteroid levels by administering the 5α-reductase inhibitor dutasteride to block conversion of progesterone to its neurosteroid metabolite allopregnanolone in women with premenstrual dysphoric disorder (PMDD) and in asymptomatic control women."9.225α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder. ( Cintron, D; Khine, KK; Koziol, DE; Martinez, PE; Morrow, AL; Nieman, LK; Rubinow, DR; Schiller, CE; Schmidt, PJ; Thompson, KD, 2016)
" To test this hypothesis, we stabilized neurosteroid levels by administering the 5α-reductase inhibitor dutasteride to block conversion of progesterone to its neurosteroid metabolite allopregnanolone in women with premenstrual dysphoric disorder (PMDD) and in asymptomatic control women."5.225α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder. ( Cintron, D; Khine, KK; Koziol, DE; Martinez, PE; Morrow, AL; Nieman, LK; Rubinow, DR; Schiller, CE; Schmidt, PJ; Thompson, KD, 2016)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martinez, PE1
Rubinow, DR1
Nieman, LK1
Koziol, DE1
Morrow, AL1
Schiller, CE1
Cintron, D1
Thompson, KD1
Khine, KK1
Schmidt, PJ1

Trials

1 trial available for androsterone and Premenstrual Dysphoric Disorder

ArticleYear
5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:4

    Topics: 5-alpha Reductase Inhibitors; Adult; Androsterone; Cholestenone 5 alpha-Reductase; Double-Blind Meth

2016