Page last updated: 2024-11-07

androsterone and Hypergonadotropic Hypogonadism

androsterone has been researched along with Hypergonadotropic Hypogonadism in 31 studies

Research Excerpts

Excerpt	Relevance	Reference
"The CSF testosterone, dihydrotestosterone, and androsterone levels were significantly lower during hypogonadism (P=."	3.73	Monoamines and neurosteroids in sexual function during induced hypogonadism in healthy men. ( Berlin, K; Bloch, M; Kevala, KR; Kim, HY; Rubinow, DR; Schmidt, PJ, 2006)
" Antiepileptic drugs, particularly classical ones, substantially modify bioavailability of androgens and can inhibit the activity of hypothalamo-pituitary-testicular axis, and--in a consequence--aggravate hypogonadism."	2.46	[Androgens and epilepsy]. ( Mróz, K; Mróz, T; Tutka, P, 2010)

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (90.32)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (3.23)	29.6817
2010's	2 (6.45)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Savkovic, S	1
Lim, S	1
Jayadev, V	1
Conway, A	1
Turner, L	1
Curtis, D	1
Goebel, C	1
Handelsman, DJ	1
Mróz, T	1
Mróz, K	1
Tutka, P	1
LIPSETT, MB	1
KORENMAN, SG	1
MATTHEWS, WB	1
RUNDLE, AT	1
SCHOEN, EJ	1
DENEVE, L	1
VERMEULEN, A	1
LOTTI, G	1
MARCENARO, A	1
MENOZZI, PG	1
Bloch, M	1
Rubinow, DR	1
Berlin, K	1
Kevala, KR	1
Kim, HY	1
Schmidt, PJ	1
Christiansen, P	2
Metcalf, MG	2
Cowles, RJ	1
Landyshev, IuS	1
Mishuk, VP	1
Schmidt, H	1
Starcevic, Z	1
Teller, WM	1
Krese, A	1
Horký, K	2
Küchel, O	2
Gregorvá, I	1
Stárka, L	2
Zimprich, H	1
Jänne, O	1
Perheentupa, J	1
Vihko, R	1
Gregorová, I	1
Scurry, MT	1
Bruton, J	1
Barry, KG	1
Boon, DA	1
Keenan, RE	1
Salunwhite, WR	1
Aceto, T	1
Crook, D	1
Jeffcoate, SL	1
Brooks, RV	1
Lim, NY	1
London, DR	1
Prunty, FT	1
Spathis, GS	1
Luisi, M	1
Franchi, F	1
Romanelli, R	1
Fassorra, C	1
Neri, R	1
Barletta, D	1
Bozzi, M	1
Aakvaag, A	2
Ludvik, W	1
Teller, W	1
Mauvais-Jarvis, P	1
Floch, HH	1
Bercovici, JP	1
Vogt, JH	1
Norman, N	1
Landau, RL	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
The Effects of Aromatase Inhibition and Testosterone Replacement in Sex Steroids, Pituitary Hormones, Markers of Bone Turnover, Muscle Strength, and Cognition in Older Men[NCT00104572]			Phase 2	44 participants (Actual)	Interventional	2004-03-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Effect of Testosterone Gel vs. Anastrozole on Bone Mineral Density

bone mineral density lumbar spine for all arms testosterone gel, anastrozole and placebo (NCT00104572)
Timeframe: 1 year

Intervention	g/cm2 (Mean)
Transdermal Testosterone	0.042
Aromatase Inhibitor	0.008
Placebo	0.047

Effect of Testosterone Gel vs. Anastrozole on Glucose Tolerance/Lipid Metabolism

"Primary outcome HOMA-IR for all groups testosterone gel, anastrozole and placebo Insulin resistance measure by HOMA-IR is a score if a person is insulin resistance the score should be between minimum 0.7- maximum 2 or more.~Absolute changes in HOMAIR in all treatment arms, calculation time frame 1 year minus baseline point." (NCT00104572)
Timeframe: 1 year

Intervention	score on a scale (Mean)
Transdermal Testosterone	-0.05
Aromatase Inhibitor	0.15
Placebo	-0.11

Effect of Testosterone Gel vs. Anastrozole on Prostate Volume/Prostate Specific Antigen Levels/Urinary Function

"rectal ultrasound prostate volume for all groups testosterone gel, anastrozole and placebo.~Absolute changes in prostate volume in all treatment arms, calculation time frame 1 year minus baseline point." (NCT00104572)
Timeframe: 1 year

Intervention	cc (Mean)
Transdermal Testosterone	4.5
Aromatase Inhibitor	-1.66
Placebo	-1.05

Effect of Testosterone Gel vs. Anastrozole on Pulsatile Growth Hormone Release

Overnight Growth hormone measures (total hormone secretion) for groups testosterone gel, anastrozole and placebo (NCT00104572)
Timeframe: 1 year

Intervention	ng/ml/8h (Mean)
Transdermal Testosterone	5.8
Aromatase Inhibitor	10
Placebo	7.7

Reviews

2 reviews available for androsterone and Hypergonadotropic Hypogonadism

Article	Year
[Androgens and epilepsy]. Przeglad lekarski, 2010, Volume: 67, Issue:11 Topics: Androgens; Androsterone; Animals; Anticonvulsants; Comorbidity; Drug Synergism; Epilepsy; Humans; Hy	2010
ANDROGEN METABOLISM. JAMA, 1964, Nov-23, Volume: 190 Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Androsterone; Blood; Chorionic Go	1964

Trials

1 trial available for androsterone and Hypergonadotropic Hypogonadism

Article	Year
Qualitative alterations in urinary 17-ketosteroid excretion during aminoglutethimide administration. The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2 Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Aminoglutethimide; Androsterone; Aniline Compounds; A	1969

Other Studies

28 other studies available for androsterone and Hypergonadotropic Hypogonadism

Article	Year
Urine and Serum Sex Steroid Profile in Testosterone-Treated Transgender and Hypogonadal and Healthy Control Men. The Journal of clinical endocrinology and metabolism, 2018, 06-01, Volume: 103, Issue:6 Topics: Adolescent; Adult; Androgens; Androsterone; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol;	2018
FAMILIAL CEREBELLAR ATAXIA AND HYPOGONADISM. Brain : a journal of neurology, 1964, Volume: 87 Topics: Adrenal Cortex Hormones; Androsterone; Ataxia; Cerebellar Ataxia; Fluids and Secretions; Genetics, M	1964
DIMINISHED TESTICULAR FUNCTION IN "MALE TURNER'S SYNDROME". The Journal of clinical endocrinology and metabolism, 1965, Volume: 25 Topics: 17-Ketosteroids; Adolescent; Androsterone; Chorionic Gonadotropin; Chromosome Aberrations; Chromosom	1965
THE DETERMINATION OF 17-OXOSTEROID SULPHATES IN HUMAN PLASMA. The Journal of endocrinology, 1965, Volume: 32 Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenalectomy; Androsterone; Blood Chemical Analysis;	1965
[Hypogonadism with hyperadrenocorticism with increased urinary elimination of androsterone and ethiocholanolone]. Archivio "E. Maragliano" di patologia e clinica, 1961, Volume: 17 Topics: Adrenal Cortex; Adrenal Cortex Diseases; Adrenocortical Hyperfunction; Androgens; Androsterone; Huma	1961
Monoamines and neurosteroids in sexual function during induced hypogonadism in healthy men. Archives of general psychiatry, 2006, Volume: 63, Issue:4 Topics: Adolescent; Adult; Affect; Androsterone; Cross-Over Studies; Dihydrotestosterone; Double-Blind Metho	2006
Urinary gonadotrophins in the Sertoli-Cell-only syndrome. Acta endocrinologica, 1975, Volume: 78, Issue:1 Topics: Adult; Androgens; Androsterone; Biological Assay; Biopsy; Castration; Dehydroepiandrosterone; Dexame	1975
Response of plasma testosterone, urinary 17-oxosteroids, oestrogens, and androsterone plus aetiocholanolone to human chorionic gonadotrophin in dexamethasone-suppressed men. Clinical endocrinology, 1976, Volume: 5, Issue:3 Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Androsterone; Chorionic Gonadotropin; Depression	1976
Studies on the relationship between spermatogenesis and urinary levels of follicle stimulating hormone and luteinizing hormone in oligospermic men. Acta endocrinologica, 1975, Volume: 78, Issue:1 Topics: Adult; Androgens; Androsterone; Biological Assay; Castration; Follicle Stimulating Hormone; Humans;	1975
[Functional status of the hypophyseal-gonadal system in patients with chronic bronchitis]. Terapevticheskii arkhiv, 1986, Volume: 58, Issue:4 Topics: 17-Ketosteroids; Adult; Androsterone; Bronchitis; Chronic Disease; Etiocholanolone; Follicle Stimula	1986
[The diagnostic significance of testosterone, 17-ketosteroids and estrogen secretion in male hypogonadism]. Klinische Wochenschrift, 1965, Dec-01, Volume: 43, Issue:23 Topics: Adult; Androsterone; Animals; Castration; Chromatography; Dehydroepiandrosterone; Estradiol; Estriol	1965
[Excretion of C-19 and C21 steroids in the urine under normal and pathological conditions of development and maturation]. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1967, Volume: 142, Issue:3 Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androsterone; Carbon Isotopes; Child; Child, Presch	1967
[Steroid spectrum of diabetic men in relationship to their potency]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1966, Oct-01, Volume: 21, Issue:19 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androsterone; Cortisone; Dehydroepiandrosterone;	1966
[Clinical and biochemical studies in a female patient with mixed gonadal dysgenesis]. Wiener klinische Wochenschrift, 1969, Jun-20, Volume: 81, Issue:25 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Androsterone; Body	1969
Plasma and urinary steroids in an eight-year-old boy with 3-beta-hydxysteroid dehydrogenase deficiency. The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:2 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aldosterone; Androsterone; Child; Dehydroepiandro	1970
Effect of aminoglutethimide on extraglandular metabolism of exogenous testosterone. Metabolism: clinical and experimental, 1971, Volume: 20, Issue:3 Topics: 17-Ketosteroids; Adult; Aminoglutethimide; Androsterone; Aniline Compounds; Anticonvulsants; Dehydro	1971
The effect of chorionic gonadotropin on steroid excretion. Archives of internal medicine, 1971, Volume: 128, Issue:4 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adolescent; Adult; Androsterone; Chorionic G	1971
Conjugated and unconjugated plasma androgens in normal children. Pediatric research, 1972, Volume: 6, Issue:2 Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androgens; Androstanes; Androsterone; Bromine; Carb	1972
The routine measurement of urinary 17-oxosteroids and 17-oxogenic steroids using gas-liquid chromatography. Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 40, Issue:1 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adult; Androgens; Androsterone; Chromat	1972
Androgen production in hypogonadal men. The Journal of endocrinology, 1967, Volume: 37, Issue:4 Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgens; Androsterone; Carbon Isotopes; Chorionic Go	1967
The excretion of androsterone and etiocholanolone as a function of adrenocrotical and gonadal activity. Clinical biochemistry, 1972, Volume: 5, Issue:1 Topics: Adolescent; Adrenal Glands; Adrenal Insufficiency; Adult; Aged; Androsterone; Child; Chorionic Gonad	1972
[Radioimmunologic determination of plasma progesterone. Preliminary note]. Folia endocrinologica, 1972, Volume: 25, Issue:5 Topics: Androstenedione; Androsterone; Antibodies; Corticosterone; Estradiol; Female; Hirsutism; Humans; Hyd	1972
[Hormonal diagnosis in hypogonadism]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, May-20, Volume: 92, Issue:14 Topics: Androsterone; Chorionic Gonadotropin; Estriol; Humans; Hypogonadism; Luteinizing Hormone; Male; Pitu	1972
[Basic principles of modern androgenic therapy]. Der Urologe, 1970, Volume: 9, Issue:1 Topics: Androgens; Androsterone; Humans; Hypogonadism; Infertility, Male; Klinefelter Syndrome; Male; Methyl	1970
[Adrenal cortex hormones in prepuberty and puberty]. Wiener klinische Wochenschrift, 1971, Jun-11, Volume: 83, Issue:23 Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Medulla; Adult; Aldosterone;	1971
Studies on testosterone metabolism in human subjects with normal and pathological sexual differentiation. The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:4 Topics: 17-Ketosteroids; Adult; Androgen-Insensitivity Syndrome; Androstanes; Androsterone; Carbon Isotopes;	1968
[The effect of chorionic gonadotropin on plasma testosterone in men]. Nordisk medicin, 1969, Aug-21, Volume: 82, Issue:34 Topics: Adolescent; Adult; Aged; Androsterone; Chorionic Gonadotropin; Estriol; Etiocholanolone; Humans; Hyp	1969
Tests of testicular function. JAMA, 1969, Jan-13, Volume: 207, Issue:2 Topics: 17-Ketosteroids; Androgens; Androsterone; Estrogens; Fertility; Humans; Hypogonadism; Infertility, M	1969