androsterone has been researched along with Chagas Disease in 2 studies
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epiandrosterone (EA) is an uncompetitive inhibitor of trypanosomal G6PDH for which its binding site to the enzyme remains unknown." | 1.43 | Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi. ( Botta, M; Comini, MA; Hamilton, N; Medeiros, A; Moraca, F; Ortiz, C, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ortiz, C | 1 |
| Moraca, F | 1 |
| Medeiros, A | 1 |
| Botta, M | 1 |
| Hamilton, N | 1 |
| Comini, MA | 1 |
| Gupta, S | 1 |
| Cordeiro, AT | 1 |
| Michels, PA | 1 |
2 other studies available for androsterone and Chagas Disease
| Article | Year |
|---|---|
Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi.
Topics: Androsterone; Binding Sites; Chagas Disease; Glucosephosphate Dehydrogenase; Humans; Molecular Docki | 2016 |
Glucose-6-phosphate dehydrogenase is the target for the trypanocidal action of human steroids.
Topics: Androsterone; Cell Line; Chagas Disease; Dehydroepiandrosterone; Dose-Response Relationship, Drug; D | 2011 |