androsterone has been researched along with Cancer of Prostate in 43 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The classification of the anti-androgens, their indications, side-effects, dosage schemes and results of treatment are reviewed." | 2.36 | [Clinical aspects of the anti-androgens]. ( Holtzhausen, GH, 1979) |
| "Inanition and obesity have been shown to alter steroid metabolism but it is not known whether nutritional "microdifferences" (i." | 2.35 | Hormone profiles in hormone-dependent cancers. ( Bradlow, HL; Fishman, J; Hellman, L; Zumoff, B, 1975) |
| "In castration-resistant prostate cancer patients, levels of androstenedione were significantly associated with testosterone level, while testosterone was the only steroid associated with dihydrotestosterone levels." | 1.72 | Extensive Alteration of Androgen Precursor Levels After Castration in Prostate Cancer Patients and Their Association With Active Androgen Level. ( Caron, P; Guillemette, C; Lacombe, L; Lévesque, É; Morin, F; Neveu, B; Pouliot, F; Rouleau, M; Toren, P; Turcotte, V, 2022) |
| "Human prostate cancer tumors were procured from the patients who underwent radical prostatectomy without any neoadjuvant therapy." | 1.62 | Steroidogenesis in Peripheral and Transition Zones of Human Prostate Cancer Tissue. ( Adomat, H; Chin, MY; Deb, S; Gleave, ME; Hurtado-Coll, A; Pham, S; Tomlinson Guns, ES, 2021) |
| "Fifty-five healthy men with localized prostate cancer were enrolled in this cross-sectional study at a single academic center." | 1.36 | Radical prostatectomy: influence on serum and urinary androgen levels. ( Akre, O; Ekström, L; Gustafsson, O; Kjellman, A; Olsson, M; Rane, A; Schulze, J, 2010) |
| "LNCaP, a human prostate cancer cell line, metabolizes testosterone into a variety of 5 alpha-reduced C19 steroids, such as dihydrotestosterone (DHT), androstane-3 alpha, 17 beta-diol (3 beta, 17 beta-DIOL), and androsterone (ADT)." | 1.29 | Glucuronosyltransferase activity in human cancer cell line LNCaP. ( Bélanger, A; Guillemette, C, 1995) |
| "In a specimen derived from metastatic prostate cancer we have reported a point mutation in the AR gene that leads to a single amino acid exchange in the ligand binding domain of the receptor." | 1.29 | Activation of two mutant androgen receptors from human prostatic carcinoma by adrenal androgens and metabolic derivatives of testosterone. ( Bartsch, G; Cato, AC; Culig, Z; Gast, A; Hittmair, A; Hobisch, A; Klocker, H; Peterziel, H; Radmayr, C; Stober, J, 1996) |
| "Ten castrated patients with prostatic cancer received flutamide (FLU) alone for 2 months and, afterwards, the combined therapy of FLU and AG for 2 months." | 1.27 | Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate. ( Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F, 1987) |
| "In these prostatic cancer patients, plasma androgen levels decreased, while estrogen levels increased." | 1.26 | Effect of diet on plasma and urinary hormones in South African black men with prostatic cancer. ( Garbaczewski, L; Hill, P; Walker, AR; Wynder, EL, 1982) |
| "In patients with breast and prostate cancer hormone excretion patterns differ in a similar way from patterns in persons without cancer." | 1.24 | HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL. ( HOPKINS, CE; MARMORSTON, J; STERN, E; WEINER, JM, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (55.81) | 18.7374 |
| 1990's | 5 (11.63) | 18.2507 |
| 2000's | 4 (9.30) | 29.6817 |
| 2010's | 5 (11.63) | 24.3611 |
| 2020's | 5 (11.63) | 2.80 |
| Authors | Studies |
|---|---|
| Djigoué, GB | 1 |
| Kenmogne, LC | 1 |
| Roy, J | 3 |
| Maltais, R | 4 |
| Poirier, D | 4 |
| Boutin, S | 1 |
| Rouleau, M | 1 |
| Neveu, B | 1 |
| Caron, P | 2 |
| Morin, F | 1 |
| Toren, P | 1 |
| Lacombe, L | 1 |
| Turcotte, V | 1 |
| Lévesque, É | 2 |
| Guillemette, C | 4 |
| Pouliot, F | 1 |
| Deb, S | 1 |
| Chin, MY | 1 |
| Pham, S | 1 |
| Adomat, H | 1 |
| Hurtado-Coll, A | 1 |
| Gleave, ME | 1 |
| Tomlinson Guns, ES | 1 |
| Cortés-Benítez, F | 1 |
| Perreault, M | 1 |
| Chi, JT | 1 |
| Lin, PH | 1 |
| Tolstikov, V | 1 |
| Oyekunle, T | 1 |
| Alvarado, GCG | 1 |
| Ramirez-Torres, A | 1 |
| Chen, EY | 1 |
| Bussberg, V | 1 |
| Chi, B | 1 |
| Greenwood, B | 1 |
| Sarangarajan, R | 1 |
| Narain, NR | 1 |
| Kiebish, MA | 1 |
| Freedland, SJ | 1 |
| Mostaghel, EA | 1 |
| Nelson, PS | 1 |
| Lange, P | 1 |
| Lin, DW | 1 |
| Taplin, ME | 1 |
| Balk, S | 1 |
| Ellis, W | 1 |
| Kantoff, P | 1 |
| Marck, B | 1 |
| Tamae, D | 1 |
| Matsumoto, AM | 1 |
| True, LD | 1 |
| Vessella, R | 1 |
| Penning, T | 1 |
| Hunter Merrill, R | 1 |
| Gulati, R | 1 |
| Montgomery, B | 1 |
| Neuhaus, EM | 1 |
| Zhang, W | 1 |
| Gelis, L | 1 |
| Deng, Y | 1 |
| Noldus, J | 1 |
| Hatt, H | 1 |
| Olsson, M | 1 |
| Ekström, L | 1 |
| Schulze, J | 1 |
| Kjellman, A | 1 |
| Akre, O | 1 |
| Rane, A | 1 |
| Gustafsson, O | 1 |
| Fournier, MA | 1 |
| Dhyani, MV | 1 |
| Satpati, D | 1 |
| Korde, A | 1 |
| Banerjee, S | 1 |
| BRADSHAW, LR | 1 |
| BAGNESS, JE | 1 |
| PYRAH, LN | 1 |
| RAPER, FP | 1 |
| STERN, E | 3 |
| HOPKINS, CE | 3 |
| WEINER, JM | 1 |
| MARMORSTON, J | 3 |
| ROHL, L | 1 |
| LOMBARDO, LJ | 2 |
| MYERS, SM | 2 |
| GIERSON, H | 2 |
| ACEVEDO, HF | 1 |
| GOLDZIEHER, JW | 1 |
| Mitamura, K | 1 |
| Setaka, M | 1 |
| Shimada, K | 1 |
| Honma, S | 1 |
| Namiki, M | 1 |
| Koh, E | 1 |
| Mizokami, A | 1 |
| Kaeding, J | 1 |
| Bouchaert, E | 1 |
| Bélanger, J | 1 |
| Chouinard, S | 1 |
| Verreault, M | 1 |
| Larouche, O | 1 |
| Pelletier, G | 1 |
| Staels, B | 1 |
| Bélanger, A | 7 |
| Barbier, O | 1 |
| Schweikert, HU | 1 |
| Hein, HJ | 1 |
| Romijn, JC | 1 |
| Schröder, FH | 1 |
| Isurugi, K | 1 |
| Kanazawa, M | 1 |
| Yanaihara, T | 1 |
| Kambegawa, A | 1 |
| Hill, P | 1 |
| Wynder, EL | 1 |
| Garbaczewski, L | 1 |
| Walker, AR | 1 |
| Morioka, M | 1 |
| Takeda, K | 1 |
| Mitsuhata, N | 1 |
| Ohashi, T | 1 |
| Ohmori, H | 1 |
| Saito, T | 1 |
| Kanbegawa, A | 1 |
| Lukkarinen, O | 1 |
| Hammond, GL | 4 |
| Kontturi, M | 3 |
| Vihko, R | 4 |
| Leinonen, P | 1 |
| Hum, DW | 2 |
| Bélanger, G | 1 |
| Beaulieu, M | 1 |
| Marcotte, B | 1 |
| Culig, Z | 1 |
| Stober, J | 1 |
| Gast, A | 1 |
| Peterziel, H | 1 |
| Hobisch, A | 1 |
| Radmayr, C | 1 |
| Hittmair, A | 1 |
| Bartsch, G | 1 |
| Cato, AC | 1 |
| Klocker, H | 1 |
| Guess, HA | 1 |
| Friedman, GD | 1 |
| Sadler, MC | 1 |
| Stanczyk, FZ | 2 |
| Vogelman, JH | 1 |
| Imperato-McGinley, J | 1 |
| Lobo, RA | 1 |
| Orentreich, N | 1 |
| Wu, AH | 1 |
| Whittemore, AS | 1 |
| Kolonel, LN | 1 |
| John, EM | 1 |
| Gallagher, RP | 1 |
| West, DW | 1 |
| Vihko, P | 1 |
| Holtzhausen, GH | 1 |
| Kjoseland, O | 1 |
| Tveter, KJ | 1 |
| Attramadal, A | 1 |
| Hansson, V | 1 |
| Haugen, HN | 1 |
| Mathisen, W | 1 |
| Ruokonen, A | 1 |
| Koskela, E | 1 |
| Zumoff, B | 1 |
| Fishman, J | 1 |
| Bradlow, HL | 1 |
| Hellman, L | 1 |
| Brochu, M | 3 |
| Cliche, J | 1 |
| Dupont, A | 2 |
| Cusan, L | 2 |
| Labrie, F | 2 |
| Brehmer, B | 1 |
| Marquardt, H | 1 |
| Madsen, PO | 1 |
| Garnham, JR | 1 |
| Bulbrook, RD | 1 |
| Wang, DY | 1 |
| Bird, CE | 1 |
| Clark, AF | 1 |
| Harkness, RA | 1 |
| Bell, ET | 1 |
| Loraine, JA | 1 |
| Ismail, AA | 1 |
| Morse, WI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maximal Suppression of the Androgen Axis in Clinically Localized Prostate Cancer[NCT00298155] | Phase 2 | 35 participants (Actual) | Interventional | 2006-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Tissue dihydrotesterone (DHT) (NCT00298155)
Timeframe: After 12 weeks of neoadjuvant androgen deprivation
| Intervention | ng/g (Mean) |
|---|---|
| Group 1 | 0.03 |
| Group 2 | 0.06 |
| Group 3 | 0.03 |
Serum DHT (NCT00298155)
Timeframe: After 12 weeks of neoadjuvant androgen deprivation
| Intervention | ng/dL (Mean) |
|---|---|
| Group 1 | 4.2 |
| Group 2 | 3.6 |
| Group 3 | 5.7 |
2 reviews available for androsterone and Cancer of Prostate
| Article | Year |
|---|---|
[Clinical aspects of the anti-androgens].
Topics: 17-Ketosteroids; Acne Vulgaris; Adrenal Hyperplasia, Congenital; Androgen Antagonists; Androgens; An | 1979 |
Hormone profiles in hormone-dependent cancers.
Topics: Adrenalectomy; Adult; Age Factors; Androgens; Androsterone; Breast Neoplasms; China; Epidemiologic M | 1975 |
3 trials available for androsterone and Cancer of Prostate
| Article | Year |
|---|---|
The influence of low-carbohydrate diets on the metabolic response to androgen-deprivation therapy in prostate cancer.
Topics: Aged; Androgen Antagonists; Androsterone; Antineoplastic Agents, Hormonal; Diet, Carbohydrate-Restri | 2021 |
Targeted androgen pathway suppression in localized prostate cancer: a pilot study.
Topics: 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Androgen Antagonists; Androgen Receptor Antag | 2014 |
The effects of clomiphene on endocrine function in male patients with adrenocortical infufficiency and following castration.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adrenal Glands; Adrenal Insufficiency; | 1968 |
38 other studies available for androsterone and Cancer of Prostate
| Article | Year |
|---|---|
Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3.
Topics: 17-Hydroxysteroid Dehydrogenases; Androgens; Animals; Carbamates; Cell Line, Tumor; Drug Design; Enz | 2015 |
Formation of 5α-dihydrotestosterone from 5α-androstane-3α,17β-diol in prostate cancer LAPC-4 cells - Identifying inhibitors of non-classical pathways producing the most potent androgen.
Topics: Androgens; Androstane-3,17-diol; Cell Line, Tumor; Dihydrotestosterone; Humans; Male; Prostatic Neop | 2020 |
Extensive Alteration of Androgen Precursor Levels After Castration in Prostate Cancer Patients and Their Association With Active Androgen Level.
Topics: Androgen Antagonists; Androgens; Androstenedione; Androsterone; Dehydroepiandrosterone; Dihydrotesto | 2022 |
Steroidogenesis in Peripheral and Transition Zones of Human Prostate Cancer Tissue.
Topics: Androstenedione; Androsterone; Chromatography, High Pressure Liquid; Humans; Male; Mass Spectrometry | 2021 |
16-Picolyl-androsterone derivative exhibits potent 17β-HSD3 inhibitory activity, improved metabolic stability and cytotoxic effect on various cancer cells: Synthesis, homology modeling and docking studies.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstanes; Androsterone; Animals; Antineoplastic Agents; Cell Li | 2021 |
Activation of an olfactory receptor inhibits proliferation of prostate cancer cells.
Topics: Androsterone; Calcium; Cell Division; Cell Line, Tumor; Humans; JNK Mitogen-Activated Protein Kinase | 2009 |
Radical prostatectomy: influence on serum and urinary androgen levels.
Topics: Aged; Androgens; Androstane-3,17-diol; Androsterone; Cross-Sectional Studies; Dihydrotestosterone; F | 2010 |
Development of 3-substituted-androsterone derivatives as potent inhibitors of 17β-hydroxysteroid dehydrogenase type 3.
Topics: 17-Hydroxysteroid Dehydrogenases; Androsterone; Enzyme Inhibitors; HEK293 Cells; Humans; Inhibitory | 2011 |
Synthesis and preliminary bioevaluation of 99mTc(CO)3-17α-triazolylandrost-4-ene-3-one derivative prepared via click chemistry route.
Topics: Androsterone; Animals; Cell Line, Tumor; Click Chemistry; Humans; Male; Organotechnetium Compounds; | 2011 |
A STUDY OF STEROID EXCRETION IN PATIENTS WITH PROSTATIC CANCER.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androsterone; Biopsy; Cortisone; Dehydroepiandrosterone; D | 1964 |
HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androsterone; Breast Neoplasms; Creatine; Creatinine | 1964 |
PROSTATIC AND BLADDER TUMOURS STUDIED IN VITRO ON THE RESPONSE TO ANDROSTERONE AND AN ORTHO-AMINOPHENOL.
Topics: Aminophenols; Androsterone; Glucuronidase; Humans; In Vitro Techniques; Male; ortho-Aminobenzoates; | 1964 |
URINARY EXCRETION OF ESTRONE, ESTRADIOL AND ESTRIOL BY PATIENTS WITH PROSTATIC CANCER AND BENIGN PROSTATIC HYPERTROPHY.
Topics: Androsterone; Estradiol; Estriol; Estrone; Humans; Male; Mice; Prostatic Hyperplasia; Prostatic Neop | 1965 |
URINARY EXCRETION OF NEUTRAL 17-KETOSTEROIDS AND PREGNANEDIOL BY PATIENTS WITH PROSTATIC CANCER AND BENIGN PROSTATIC HYPERTROPHY.
Topics: 17-Ketosteroids; Androsterone; Blood Glucose; Blood Urea Nitrogen; Creatine; Creatinine; Etiocholano | 1965 |
FURTHER STUDIES ON THE METABOLISM OF 4-(4-14C)ANDROSTENE-3,17-DIONE BY NORMAL AND PATHOLOGICAL HUMAN PROSTATE TISSUE.
Topics: Androgens; Androsterone; Chromatography; Humans; Hydroxysteroid Dehydrogenases; Male; Metabolism; Pr | 1965 |
Determination of sulfates of androsterone and epiandrosterone in human serum using isotope diluted liquid chromatography-electrospray ionization-mass spectrometry.
Topics: Adult; Aged; Androsterone; Chromatography, Liquid; Dehydroepiandrosterone Sulfate; Deuterium; Humans | 2005 |
Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.
Topics: Androgens; Androsterone; Cell Line, Tumor; DNA-Binding Proteins; Epithelial Cells; Gene Expression R | 2008 |
Testosterone metabolism of fibroblasts grown from prostatic carcinoma, benign prostatic hyperplasia and skin fibroblasts.
Topics: Androstanes; Androsterone; Carcinoma; Cells, Cultured; Chromatography, Thin Layer; Dihydrotestostero | 1982 |
Responses of serum levels of testicular steroid hormones to hCG stimulation in patients with prostatic cancer and benign prostatic hypertrophy.
Topics: Aged; Androsterone; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Humans; Male; Middle Age | 1981 |
Effect of diet on plasma and urinary hormones in South African black men with prostatic cancer.
Topics: Aged; Androgens; Androsterone; Black People; Dehydroepiandrosterone; Diet; Estriol; Estrogens; Estro | 1982 |
[Endogenous androgen levels of human prostatic tissues].
Topics: Aged; Androgens; Androsterone; Dihydrotestosterone; Humans; Male; Middle Aged; Prostate; Prostatic H | 1982 |
Long-term effects of endocrine treatment on serum steroids in advanced prostatic carcinoma patients.
Topics: Aged; Androstenedione; Androsterone; Castration; Dehydroepiandrosterone; Dihydrotestosterone; Estrad | 1980 |
Testosterone and some of its precursors and metabolites in the human epididymis.
Topics: Aged; Androstane-3,17-diol; Androstenedione; Androsterone; Dihydrotestosterone; Epididymis; Estrogen | 1980 |
Glucuronosyltransferase activity in human cancer cell line LNCaP.
Topics: Androstane-3,17-diol; Androsterone; Cell Line; Dihydrotestosterone; Glucuronates; Glucuronosyltransf | 1995 |
Specificity of glucuronosyltransferase activity in the human cancer cell line LNCaP, evidence for the presence of at least two glucuronosyltransferase enzymes.
Topics: Adenocarcinoma; Androstane-3,17-diol; Androsterone; Binding, Competitive; Dihydrotestosterone; Estra | 1995 |
Expression of transcripts encoding steroid UDP-glucuronosyltransferases in human prostate hyperplastic tissue and the LNCaP cell line.
Topics: Androsterone; Base Sequence; Blotting, Northern; Cell Line; Dihydrotestosterone; DNA Probes; Gene Ex | 1995 |
Activation of two mutant androgen receptors from human prostatic carcinoma by adrenal androgens and metabolic derivatives of testosterone.
Topics: Androgens; Androstenedione; Androsterone; Animals; Base Sequence; Blood Proteins; Complement C4; DNA | 1996 |
5 alpha-reductase activity and prostate cancer: a case-control study using stored sera.
Topics: Aged; Aged, 80 and over; Androsterone; Biomarkers, Tumor; Case-Control Studies; Cholestenone 5 alpha | 1997 |
Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men.
Topics: Age Distribution; Aged; Aged, 80 and over; Aging; Analysis of Variance; Androstane-3,17-diol; Andros | 2001 |
Serum steroids in normal males and patients with prostatic diseases.
Topics: Adult; Aged; Aging; Androstenedione; Androsterone; Dihydrotestosterone; Estradiol; Humans; Hydroxypr | 1978 |
Metabolism of testosterone in the human prostate and seminal vesicles.
Topics: Adenocarcinoma; Androstanes; Androstenedione; Androsterone; Culture Techniques; Humans; Hyperplasia; | 1977 |
The simultaneous radioimmunoassay of seven steroids in human spermatic and peripheral venous blood.
Topics: Adult; Aged; Androstenedione; Androsterone; Dihydrotestosterone; Hormones; Humans; Male; Middle Aged | 1977 |
Levels of plasma steroid glucuronides in intact and castrated men with prostatic cancer.
Topics: Aged; Androgens; Androstane-3,17-diol; Androstenediol; Androsterone; Dehydroepiandrosterone; Dihydro | 1986 |
Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate.
Topics: Aged; Aminoglutethimide; Androstane-3,17-diol; Androstanols; Androsterone; Anilides; Dehydroepiandro | 1987 |
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstene | 1988 |
Growth and hormonal response of cells derived from carcinoma and hyperplasia of the prostate in monolayer cell culture. A possible in vitro model for clinical chemotherapy.
Topics: Adenocarcinoma; Androsterone; Carcinoma; Cell Division; Cells, Cultured; Diethylstilbestrol; Estrone | 1972 |
Conjugated and unconjugated dehydroepiandrosterone, aetiocholanolone and androsterone in the peripheral plasma of patients with cancer of the breast, ovary, uterus or prostate.
Topics: Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Male | 1969 |
A single method for determination of urine steroids. I. Levels of testosterone, epitestosterone and 17-ketosteroid fractions. II. Specific activities of testosterone, androsterone and etiocholanolone and production rate of testosterone following administr
Topics: 17-Ketosteroids; Adolescent; Adult; Aged; Androsterone; Breast Neoplasms; Carbon Isotopes; Carcinoma | 1970 |