androsterone has been researched along with Adrenal Hyperplasia, Congenital in 40 studies
Adrenal Hyperplasia, Congenital: A group of inherited disorders of the ADRENAL GLANDS, caused by enzyme defects in the synthesis of cortisol (HYDROCORTISONE) and/or ALDOSTERONE leading to accumulation of precursors for ANDROGENS. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in STEROID 21-HYDROXYLASE; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE; 3-beta-hydroxysteroid dehydrogenase (3-HYDROXYSTEROID DEHYDROGENASES); TESTOSTERONE 5-ALPHA-REDUCTASE; or steroidogenic acute regulatory protein; among others, underlie these disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " While preliminary data indicates that both 3 alpha-diolG and androsterone G (ADTG) may arise from adrenal steroid precursors, there have been no reports of C19 steroid glucuronides in women with non-classical, or late-onset congenital adrenal hyperplasia (NC-CAH), who constitute a significant proportion of the hirsute female population." | 3.68 | Plasma levels of C19 steroid glucuronides in pre-menopausal women with non-classical congenital adrenal hyperplasia. ( del Blazo, P; Ueshiba, H; Whorwood, CB, 1992) |
| "Abiraterone acetate (AA) is a prodrug for abiraterone, a potent CYP17A1 inhibitor used to suppress androgens in the treatment of prostate cancer." | 2.79 | Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency. ( Auchus, RJ; Buschur, EO; Chang, AY; Gonzalez, M; Hammer, GD; Jiao, J; Madrigal, D; Ramm, C; Smit, JW; Wang, G; Xu, XS; Yu, MK, 2014) |
| " The classification of the anti-androgens, their indications, side-effects, dosage schemes and results of treatment are reviewed." | 2.36 | [Clinical aspects of the anti-androgens]. ( Holtzhausen, GH, 1979) |
| "Youth with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency develop cardiovascular disease (CVD) risk factors of obesity and hypertension." | 1.43 | Carotid Intima-Media Thickness Is Associated with Increased Androgens in Adolescents and Young Adults with Classical Congenital Adrenal Hyperplasia. ( Dao-Tran, A; Davidowitz, E; Geffner, ME; Gilsanz, V; Kim, MS; Nguyen, E; Ryabets-Lienhard, A; Tseng, T, 2016) |
| "The treatment goal in congenital adrenal hyperplasia (CAH) is to replace glucocorticoids while avoiding androgen excess and iatrogenic Cushing's syndrome." | 1.42 | Hormonal circadian rhythms in patients with congenital adrenal hyperplasia: identifying optimal monitoring times and novel disease biomarkers. ( Backlund, PS; Crutchfield, CA; Debono, M; Gounden, V; Harrison, RF; Mallappa, A; Merke, DP; Nella, AA; Ross, RJ; Soldin, SJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (67.50) | 18.7374 |
| 1990's | 1 (2.50) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 11 (27.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamrath, C | 3 |
| Wettstaedt, L | 2 |
| Boettcher, C | 2 |
| Hartmann, MF | 3 |
| Wudy, SA | 3 |
| Auchus, RJ | 1 |
| Buschur, EO | 1 |
| Chang, AY | 1 |
| Hammer, GD | 1 |
| Ramm, C | 1 |
| Madrigal, D | 1 |
| Wang, G | 1 |
| Gonzalez, M | 1 |
| Xu, XS | 1 |
| Smit, JW | 1 |
| Jiao, J | 1 |
| Yu, MK | 1 |
| Debono, M | 1 |
| Mallappa, A | 2 |
| Gounden, V | 2 |
| Nella, AA | 1 |
| Harrison, RF | 1 |
| Crutchfield, CA | 1 |
| Backlund, PS | 1 |
| Soldin, SJ | 2 |
| Ross, RJ | 2 |
| Merke, DP | 3 |
| Stolze, BR | 1 |
| Gu, J | 1 |
| Elliott, EA | 1 |
| Masika, LS | 1 |
| Abel, BS | 1 |
| Skarulis, MC | 1 |
| Kim, MS | 1 |
| Dao-Tran, A | 1 |
| Davidowitz, E | 1 |
| Tseng, T | 1 |
| Gilsanz, V | 1 |
| Ryabets-Lienhard, A | 1 |
| Nguyen, E | 1 |
| Geffner, ME | 1 |
| Jones, CM | 1 |
| Reisch, N | 2 |
| Nikolaou, N | 1 |
| Krone, N | 2 |
| Hughes, BA | 2 |
| O'Neil, DM | 1 |
| Whitaker, MJ | 1 |
| Tomlinson, JW | 1 |
| Storbeck, KH | 1 |
| Arlt, W | 2 |
| Hochberg, Z | 1 |
| Remer, T | 1 |
| Koyama, Y | 1 |
| Homma, K | 1 |
| Fukami, M | 1 |
| Miwa, M | 1 |
| Ikeda, K | 1 |
| Ogata, T | 1 |
| Hasegawa, T | 1 |
| Murata, M | 1 |
| Taylor, NF | 1 |
| Chan, AO | 1 |
| Idkowiak, J | 1 |
| Ivison, HE | 1 |
| Abdul-Rahman, OA | 1 |
| Hendon, LG | 1 |
| Olney, AH | 1 |
| Nielsen, S | 1 |
| Harrison, R | 1 |
| Blair, EM | 1 |
| Dhir, V | 1 |
| Shackleton, CH | 1 |
| GOLD, NI | 1 |
| CRIGLER, JF | 1 |
| REFORZOMEMBRIVES, J | 1 |
| DIGNAM, WJ | 1 |
| PION, RJ | 1 |
| LAMB, EJ | 1 |
| SIMMER, HH | 1 |
| EDWARDS, RW | 1 |
| MAKIN, HL | 1 |
| BARRATT, TM | 1 |
| SORCINI, G | 1 |
| SCIARRA, F | 1 |
| CONCOLINO, G | 1 |
| RASCIO, L | 1 |
| Shibata, Y | 1 |
| Mizumoto, T | 1 |
| Kondo, S | 1 |
| Yamasaki, S | 1 |
| Ferrante, L | 1 |
| Holtzhausen, GH | 1 |
| Zhukovskiĭ, MA | 1 |
| Kuznetsova, ES | 1 |
| Grishina, VP | 1 |
| Matys, Z | 1 |
| Gregorová, I | 2 |
| Tomsová, Z | 1 |
| Jarosová, M | 1 |
| Schreiber, V | 1 |
| Whorwood, CB | 1 |
| Ueshiba, H | 1 |
| del Blazo, P | 1 |
| Dumić, M | 1 |
| Brkljacić, L | 1 |
| Mardesić, D | 1 |
| Plavsić, V | 1 |
| Lukenda, M | 1 |
| Kastelan, A | 1 |
| Rivera, R | 1 |
| Dorfman, RI | 1 |
| Forchielli, E | 1 |
| Rivarola, MA | 1 |
| Saez, JM | 1 |
| Migeon, CJ | 1 |
| Conly, PW | 1 |
| Sandberg, DH | 1 |
| Cleveland, WW | 1 |
| Göbel, P | 1 |
| Cacciari, E | 1 |
| Dallera, L | 1 |
| Tassoni, P | 1 |
| Cicognani, A | 1 |
| Miano, A | 1 |
| Garmendia, F | 1 |
| Nicolis, GL | 2 |
| Gabrilove, JL | 2 |
| Gleispach, H | 2 |
| Berger, H | 2 |
| Glatzl, J | 2 |
| Rössler, H | 2 |
| Sanghvi, A | 1 |
| Wight, C | 1 |
| Serenko, A | 1 |
| Balachandran, R | 1 |
| Horký, K | 1 |
| Kuchel, O | 1 |
| Stárka, L | 1 |
| Sohval, AR | 1 |
| Gillich, KH | 1 |
| Szamatowicz, M | 1 |
| Curtius, HC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children With Classic 21-Hydroxylase Deficiency[NCT02574910] | Phase 1 | 36 participants (Anticipated) | Interventional | 2017-08-01 | Recruiting | ||
| A Phase 1-2 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children With Classic 21-Hydroxylase Deficiency[NCT03548246] | Phase 2 | 0 participants (Actual) | Interventional | 2023-01-31 | Withdrawn (stopped due to This study plan has halted and was withdrawn from the IRB.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for androsterone and Adrenal Hyperplasia, Congenital
| Article | Year |
|---|---|
[Androsterone].
Topics: Adrenal Hyperplasia, Congenital; Amenorrhea; Androsterone; Biomarkers; Female; Humans; Hyperthyroidi | 2005 |
[Clinical aspects of the anti-androgens].
Topics: 17-Ketosteroids; Acne Vulgaris; Adrenal Hyperplasia, Congenital; Androgen Antagonists; Androgens; An | 1979 |
[Enzyme anomaly in adrenal cortex hormone synthesis].
Topics: Adrenal Hyperplasia, Congenital; Androsterone; Glucocorticoids; Humans; Hydrocortisone; Hydroxystero | 1967 |
2 trials available for androsterone and Adrenal Hyperplasia, Congenital
| Article | Year |
|---|---|
Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency.
Topics: 17-alpha-Hydroxyprogesterone; Abiraterone Acetate; Adrenal Hyperplasia, Congenital; Adult; Androgen | 2014 |
Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency.
Topics: 17-alpha-Hydroxyprogesterone; Abiraterone Acetate; Adrenal Hyperplasia, Congenital; Adult; Androgen | 2014 |
Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency.
Topics: 17-alpha-Hydroxyprogesterone; Abiraterone Acetate; Adrenal Hyperplasia, Congenital; Adult; Androgen | 2014 |
Abiraterone acetate to lower androgens in women with classic 21-hydroxylase deficiency.
Topics: 17-alpha-Hydroxyprogesterone; Abiraterone Acetate; Adrenal Hyperplasia, Congenital; Adult; Androgen | 2014 |
Effect of aminoglutethimide on urinary steroid excretion in patients with congenital adrenal hyperplasia due to incomplete 21-hydroxylase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenal Hy | 1972 |
35 other studies available for androsterone and Adrenal Hyperplasia, Congenital
| Article | Year |
|---|---|
Androgen excess is due to elevated 11-oxygenated androgens in treated children with congenital adrenal hyperplasia.
Topics: Adrenal Hyperplasia, Congenital; Androgens; Androsterone; Biomarkers; Case-Control Studies; Child; C | 2018 |
Hormonal circadian rhythms in patients with congenital adrenal hyperplasia: identifying optimal monitoring times and novel disease biomarkers.
Topics: 17-alpha-Hydroxyprogesterone; 5-alpha-Dihydroprogesterone; Adrenal Hyperplasia, Congenital; Adrenoco | 2015 |
An improved micro-method for the measurement of steroid profiles by APPI-LC-MS/MS and its use in assessing diurnal effects on steroid concentrations and optimizing the diagnosis and treatment of adrenal insufficiency and CAH.
Topics: Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Androgens; Androsterone; Chromatography, Liq | 2016 |
Carotid Intima-Media Thickness Is Associated with Increased Androgens in Adolescents and Young Adults with Classical Congenital Adrenal Hyperplasia.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Androsterone; Caro | 2016 |
The urinary steroidome of treated children with classic 21-hydroxylase deficiency.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenarche; Androgens; Androsterone; Body Height; Body | 2017 |
Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Androgens; Androst | 2017 |
Increased activation of the alternative "backdoor" pathway in patients with 21-hydroxylase deficiency: evidence from urinary steroid hormone analysis.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Androstenedione; Androsterone; Child; Child, Pre | 2012 |
Two-step biochemical differential diagnosis of classic 21-hydroxylase deficiency and cytochrome P450 oxidoreductase deficiency in Japanese infants by GC-MS measurement of urinary pregnanetriolone/ tetrahydroxycortisone ratio and 11β-hydroxyandrosterone.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Androsterone; Biomarkers; Case-Contro | 2012 |
New strategies for detecting steroid metabolic disorders--paneling vs profiling.
Topics: Adrenal Hyperplasia, Congenital; Androsterone; Female; Humans; Male; NADPH-Ferrihemoprotein Reductas | 2012 |
Prenatal diagnosis of congenital adrenal hyperplasia caused by P450 oxidoreductase deficiency.
Topics: Abnormalities, Multiple; Adrenal Hyperplasia, Congenital; Androsterone; Estriol; Female; Heterozygot | 2013 |
Influence of L-triodothyronine on steroid hormone metabolism: studies in a patient with adrenal hyperplasia (Cushing's syndrome).
Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocortical Hyp | 1963 |
[POLYCYSTIC OVARIES. ENDOCRINE ASPECTS].
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Adrenogenital Syndro | 1963 |
PLASMA ANDROGENS IN WOMEN. II. PATIENTS WITH POLYCYSTIC OVARIES AND HIRSUTISM.
Topics: Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Androgens; Androsterone; Blood Chemical Ana | 1964 |
THE STEROID 11-OXYGENATION INDEX; A RAPID METHOD FOR USE IN THE DIAGNOSIS OF CONGENITAL ADRENAL HYPERPLASIA.
Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Androsterone; Chem | 1964 |
[ADRENOGENITAL SYNDROME CAUSED BY CONGENITAL HYPERPLASIA OF THE ADRENAL CORTEX: PATHOGENETIC IMPORTANCE OF TESTOSTERONE].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenal Gland Diseases; Adre | 1964 |
[An analysis and identification of urinary steroids in normal people and patients with 21-hydroxylase deficiency and urinary excretion patterns].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adult; Aged; Androgens; Androsterone; Child; Cortisone; | 1984 |
[Complex biochemical aspects in virilizing adrenal gland syndromes].
Topics: Adrenal Hyperplasia, Congenital; Androsterone; Dehydroepiandrosterone; Etiocholanolone; Female; Huma | 1976 |
[Difficulties of differential diagnosis of androsteroma in an 8-year-old girl].
Topics: Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Androsterone; Child; Diagnosis, Differenti | 1979 |
[Urinary excretion of steroids in congenital adrenogenital syndrome with successful pregnancy (author's transl)].
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adult; Androsterone; Etiocholanolone; Female; Huma | 1977 |
Plasma levels of C19 steroid glucuronides in pre-menopausal women with non-classical congenital adrenal hyperplasia.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstane-3,17-diol; Androster | 1992 |
'Cryptic' form of congenital adrenal hyperplasia due to 21-hydroxylase deficiency in the Yugoslav population.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; A | 1985 |
A modified method for the analysis of urinary 17-ketosteroids, pregnanediol and pregnanetriol by gas liquid chromatography in normal subjects and subjects with various endocrine disorders.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Cushing Syndrom | 1967 |
Studies of androgens in patients with congenital adrenal hyperplasia.
Topics: Adolescent; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult; Androsterone; Carbon Isotopes; C | 1967 |
Steroid metabolism in premature pubarche and virilizing adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Androgens; | 1967 |
[Adrenal hirsutism (3-beta-hydroxysteroid dehydrogenase deficiency). Studies using chromatographic separation of the urinary 17-ketosteroid fraction. 3. On the differential diagnosis of adrenal hirsutism (M. Cushing, congenital adrenogenital syndrome)].
Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre | 1968 |
[Various aspects of steroidogenesis in congenital adrenogenital syndrome with or without salt loss (determination of the urinary excretion of aldosterone, androsterone, etiocholanolone, dehydroisoandrosterone, 17-hydroxy-11-desoxycorticosterone, pregnaned
Topics: Adrenal Hyperplasia, Congenital; Aldosterone; Androgens; Androsterone; Child; Child, Preschool; Dehy | 1969 |
The determination of urinary pregnanetriol and the neutral 17-ketosteroids by gas-liquid chromatography.
Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adre | 1971 |
[Congenital adrenal hyperplasia; 21-hydroxylase-deficiency combined with 17-desmolase-deficiency (author's transl)].
Topics: Adrenal Hyperplasia, Congenital; Androsterone; Chemical Phenomena; Chemistry; Dehydroepiandrosterone | 1974 |
Gas-liquid chromatography of underivatized steroids: simultaneous determination of urinary 17-ketosteroids, pregnanediol, pregnanetriol, and pregnanetriolone.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Computers; Dehy | 1974 |
[Pregnanetriolone excretion after stimulation with ACTH as a test on presumably heterozygous carriers of a 21-hydroxylase-deficiency (author's transl)].
Topics: 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Andr | 1974 |
Non-tumorous feminizing adrenogenital syndrome in the male subject.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorti | 1973 |
[Evaluation of neutral urinary steroid analysis by gas liquid chromatography using OV-210].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrena | 1971 |
[Postpuberal adrenogenital syndrome and gravidity].
Topics: 17-Ketosteroids; Abortion, Spontaneous; Adolescent; Adrenal Hyperplasia, Congenital; Age Factors; An | 1968 |
[Diagnosis and therapeutic results in cases of hirsutism in women].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adult; Androsterone; Cu | 1969 |
[Gas chromatography determination of pregnanediol, pregnanetriol and pregnanetriolone in urine].
Topics: Adrenal Hyperplasia, Congenital; Androsterone; Chemistry, Clinical; Chromatography, Gas; Glucuronida | 1966 |