androstenedione has been researched along with Cancer of Prostate in 129 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 49 (37.98) | 18.7374 |
1990's | 30 (23.26) | 18.2507 |
2000's | 12 (9.30) | 29.6817 |
2010's | 31 (24.03) | 24.3611 |
2020's | 7 (5.43) | 2.80 |
Authors | Studies |
---|---|
Djigoué, GB; Kenmogne, LC; Maltais, R; Poirier, D; Roy, J | 1 |
Chu, L; Chu, T; Ge, M; Huang, Y; Lu, Q; Shu, X | 1 |
Caron, P; Guillemette, C; Lacombe, L; Lévesque, É; Morin, F; Neveu, B; Pouliot, F; Rouleau, M; Toren, P; Turcotte, V | 1 |
Chung, YM; McManus, JM; Sharifi, N | 1 |
Beamud-Cortés, M; Bermell-Marco, L; Cauli, O; Mafla-España, MA; Rubio-Briones, J; Torregrosa, MD | 1 |
Caron, P; Ding, K; Guillemette, C; Klotz, L; Lacombe, L; Lévesque, É; Morin, F; Neveu, B; Pouliot, F; Rouleau, M; Toren, P; Vélot, L | 1 |
Adomat, H; Chin, MY; Deb, S; Gleave, ME; Hurtado-Coll, A; Pham, S; Tomlinson Guns, ES | 1 |
Bérubé, G; Oufqir, Y; Paquin, A; Reyes-Moreno, C; Sevrioukova, IF | 1 |
Abderrahman, B; Jordan, VC | 1 |
Alyamani, M; Berk, M; Hettel, D; Sharifi, N; Zhang, A | 1 |
du Toit, T; Gent, R; Swart, AC | 1 |
Kikuchi, E; Kosaka, T; Maeda, T; Miyajima, A; Nagata, H; Oya, M | 1 |
Azen, CG; Pike, MC; Stanczyk, FZ | 1 |
Chen, HL; Du, JJ; Li, YC | 1 |
O'Hanlon, LH | 1 |
Arnold, JT; Piao, YS; Sprando, R; Wiesenfeld, P | 1 |
Morgentaler, A; Traish, AM | 1 |
Stanczyk, FZ | 1 |
Bloem, LM; Schloms, L; Storbeck, KH; Swart, AC | 1 |
Audenet, F; Murez, T; Neuzillet, Y; Ripert, T; Villers, A | 1 |
Adomat, H; Beheshti, EH; Chin, MY; Deb, S; Guns, ET; Kharmate, G; Locke, J; Ming, DS; Pham, S | 1 |
Corcoran, NM; Costello, AJ; Fankhauser, M; Haviv, I; Hong, MK; Hovens, CM; Macintyre, G; Nguyen, A; Pedersen, JS; Tan, Y | 1 |
Azami, H; Baskin-Bey, E; Enjo, K; Furutani, T; Heeringa, M; Kamiyama, Y; Kikuchi, A; Kuromitsu, S; Niimi, T; Ouatas, T; Watanabe, K | 1 |
Knudsen, KE | 1 |
Auchus, RJ; Sharifi, N | 1 |
Corcoran, NM; Hong, MK; Hovens, CM | 1 |
Andrew, R; Faqehi, AM; Homer, NZ; Hughes, KA; Naredo, G; Stewart, LH; Upreti, R; Walker, BR | 1 |
Ambrosone, CB; Figg, WD; Goodman, PJ; Hoque, A; Hsing, AW; Kristal, AR; Lippman, SM; Neuhouser, ML; Parnes, HL; Platz, EA; Price, DK; Reichardt, JK; Santella, RM; Stanczyk, FZ; Tangen, CM; Thompson, IM; Till, C; vanBokhoven, A; Yao, S | 1 |
Anai, S; Fujimoto, K; Miyake, M; Nakai, Y; Tanaka, N; Tatsumi, Y | 1 |
de Jong, FH; Dits, NF; Hofland, J; Jenster, G; Schröder, FH; Steenbergen, J; van Leenders, GJ; van Weerden, WM | 1 |
Ahlem, C; Bell, D; Delorme, E; Frincke, J; Kennedy, M; Page, T; Reading, C; Stickney, D; Villegas, S; White, S | 1 |
Arai, S; Honma, S; Kobayashi, M; Miyashiro, Y; Shibata, Y; Suzuki, K; Tomaru, Y | 1 |
Chanock, SJ; Chokkalingam, AP; Chu, LW; Hayes, RB; Hsing, AW; Huang, WY; Kaaks, R; Li, Q; Menashe, I; Meyer, TE; Quraishi, SM; Rosenberg, PS; Weiss, JM; Yu, K | 1 |
Balk, SP; Bubley, GJ; Cai, C; Chen, S; Marck, B; Matsumoto, AM; Mostaghel, EA; Nelson, PS; Ng, P; Simon, NI; Wang, H | 1 |
Boevé, E; Bui, HN; de Ronde, W; Hartman, JF; Heijboer, AC; Meuleman, EJ; van Adrichem, N; van der Sluis, TM; van Moorselaar, RJ; Vis, AN | 1 |
Auchus, RJ; Chang, KH; Evaul, K; Li, R; Liu, J; Sharifi, N; Sharma, KK; Yoshimoto, J | 1 |
Arai, S; Hashimoto, K; Honma, S; Ito, K; Kashiwagi, B; Miyashiro, Y; Nakamura, Y; Sasano, H; Sekine, Y; Shibata, Y; Suzuki, K; Tomaru, Y; Uei, T | 1 |
Hartmann, MF; Kamrath, C; Wudy, S | 1 |
Broeder, CE | 1 |
Barnett, MJ; Chen, C; DiTommaso, D; Etzioni, R; Goodman, GE; Lewis, SK; Stanczyk, FZ; Weiss, NS | 1 |
Ford, OH; French, FS; Gregory, CW; Kim, D; Mohler, JL; Petrusz, P; Weaver, CM; Wilson, EM | 1 |
Bai, C; Chen, F; Freedman, L; Gambone, C; Harada, S; Kasparcova, V; Knecht, K; Leu, C; Reszka, A; Rutledge, SJ; Scafonas, A; Schmidt, A; Vogel, R; Zhang, H | 1 |
Habuchi, T; Kakinuma, H; Kato, T; Matsuura, S; Nakamura, A; Ohyama, C; Tsuchiya, N; Wang, L | 1 |
Attar, RM; Fink, BE; Gottardis, MM; Kick, EK; Lawrence, RM; Lorenzi, MV; Rizzo, CA; Ruan, Z; Salvati, ME; Spires, TE; Takenaka, I; Vite, GD; Weinmann, R; You, D | 1 |
Andriole, GL; Chatterjee, N; Crawford, ED; Fears, TR; Hayes, RB; Hsing, AW; Huang, WY; Kaaks, R; Rinaldi, S; Weiss, JM | 1 |
Carpenter, WR; Godley, PA; Robinson, WR | 1 |
Allen, NE; Appleby, P; Key, TJ; Roddam, AW | 1 |
Habib, FK | 1 |
Ghanadian, R; Masters, JR; Smith, CB | 1 |
Chilvers, CE; Dowsett, M; Easton, D; Jeffcoate, SL; Miller, J; Pocock, RD; Ponder, BA; Shearer, RJ | 1 |
Trachtenberg, J | 1 |
Hammond, GL; Kontturi, M; Lukkarinen, O; Vihko, R | 1 |
Ghanadian, R; Masters, JR; Metcalfe, SA; Smith, CB | 1 |
Marks, TA; Petrow, V | 1 |
Hammond, GL; Leinonen, P; Vihko, R | 1 |
Chisholm, GD; Elton, RA; Habib, FK; Halliday, P; Rana, A; Ross, M; Wild, R | 1 |
Geller, J | 1 |
McTavish, D; Wiseman, LR | 1 |
Bartsch, G; Cato, AC; Cronauer, MV; Culig, Z; Eberle, J; Hittmair, A; Hobisch, A; Klocker, H; Radmayr, C | 1 |
Hakky, SI; Hudson, PB; Lombardo, ME | 2 |
Boccardo, F; Decensi, A; Marroni, P; Padovani, P; Pensa, F; Torrisi, R | 1 |
Adami, HO; Andersson, SO; Bergström, R; Wide, L | 1 |
Carsol, JL; Délos, S; Ghazarossian, E; Martin, PM; Raynaud, JP | 1 |
Block, JL; Block, NL; Lokeshwar, BL | 1 |
Bartsch, G; Cato, AC; Culig, Z; Gast, A; Hittmair, A; Hobisch, A; Klocker, H; Peterziel, H; Radmayr, C; Stober, J | 1 |
di Salle, E; Giudici, D; Zaccheo, T | 1 |
Balk, SP; Bubley, GJ; Fenton, MA; Fertig, AM; Kolvenbag, G; Shuster, TD; Taplin, ME | 1 |
Aho, K; Hakama, M; Heikkilä, R; Heliövaara, M; Knekt, P; Marniemi, J; Reunanen, A | 1 |
Colciago, A; Motta, M; Negri-Cesi, P; Poletti, A | 1 |
Chang, C; Miyamoto, H | 1 |
Albanes, D; Barrett, MJ; Dorgan, JF; Hartman, TJ; Heinonen, OP; Tangrea, JA; Taylor, PR; Virtamo, J; Woodson, K | 1 |
Le Lain, R; Maharlouie, FH; Nicholls, PJ; Smith, HJ | 1 |
Habib, FK; Stitch, SR | 1 |
Attramadal, A; Djöseland, O; Hansson, V; Naess, O; Torgersen, O; Tveter, KJ; Weddington, SC | 1 |
Habib, FK; Lee, IR; Smith, PH; Stitch, SR | 1 |
Attramadal, A; Djoseland, O; Hansson, V; Naess, O; Weddington, SC | 1 |
Bard, DR; Lasnitzki, I | 1 |
Hammond, GL; Kontturi, M; Vihko, P; Vihko, R | 1 |
Schweikert, HU | 1 |
Siiteri, PK; Walsh, PC | 1 |
Di Silverio, F; Gagliardi, V; Sciarra, F; Sorcini, G | 2 |
Brownsey, BG; Cowley, TH; Griffiths, K; Harper, ME; Peeling, WB | 1 |
Attramadal, A; Hansson, V; Haugen, HN; Kjoseland, O; Mathisen, W; Tveter, KJ | 1 |
Rodriguez-Rigau, LJ; Smith, KD; Steinberger, E; Tcholakian, RK | 1 |
McCullough, B; Nitchuk, WM; Shain, SA | 1 |
Cavazos, LF; Charles, JF; Floch, HH; Leav, I; Morfin, RF; Ofner, P | 1 |
Hammond, GL; Kontturi, M; Koskela, E; Ruokonen, A; Vihko, R | 1 |
Halpern, ME; Kelch, RP; Musich, SS; Payne, AH | 1 |
Brownsey, BG; Cowley, T; Fahmy, DR; Griffiths, K; Groom, G; Harper, ME; Peeling, WB; Phillips, ME | 1 |
Albert, J; Geller, J; Geller, S; Lopez, D | 1 |
Davies, JH; Heeremans, CE; Jarman, M; McCague, R; Niessen, WM; Poon, GK; van der Greef, J; van der Hoeven, RA | 1 |
de Jong, FH; Elissen, NM; Schröder, FH; van Kreuningen, A; van Steenbrugge, GJ; van Weerden, WM | 1 |
Coombes, RC; Davies, JH; Dowsett, M; Hedley, A; Jacobs, S; Shearer, RJ | 1 |
Hudson, RW; Wherrett, D | 1 |
Davies, JH; Dowsett, M; Rowlands, MG; Shearer, RJ | 1 |
Cooper, MR; Danesi, R; Ewing, MW; Jamis-Dow, CA; La Rocca, RV; Linehan, WM; Myers, CE | 1 |
de Jong, FH; Moerings, EP; Schröder, FH; van Kreuningen, A; van Steenbrugge, GJ; van Weerden, WM | 1 |
Bartsch, G; Graf, AH; Hartmann, H; Klocker, H; Schiller, CD; Schneider, MR | 1 |
Bélanger, A; Brochu, M; Caron, S; Couture, J; Cusan, L; Dupont, A; Labrie, F; Lacoste, D; Noël, C | 1 |
Ayub, M; Levell, MJ | 1 |
Abel, PD; Asopa, R; Smith, C; Williams, G | 1 |
Carlström, K; Stege, R | 1 |
Coombes, RC; Cunningham, D; Davies, JH; Dowsett, M; Hedley, A; Malone, PR; Shearer, RJ | 1 |
Banks, PK; Brodie, AM; Inkster, SE; Koos, RD; Son, C | 1 |
Barrett-Connor, E; Garland, C; Khaw, KT; McPhillips, JB; Wingard, DL | 1 |
Cocconi, M; Martini, L; Motta, M; Serio, M; Zoppi, S | 1 |
Cummings, KB; Havlin, KH; Jordan, VC; Lange, PH; Messing, EM; Trump, DL | 1 |
Brodie, AM; Inkster, SE; King, DA; Meyer, KM; Son, C | 1 |
Carlström, K; Collste, L; Eriksson, A; Henriksson, P; Pousette, A; Stege, R; von Schoultz, B | 1 |
Bongini, M; Bozzolan, F; Doukani, A; Mauvais-Jarvis, P; Poizat, R; Wright, F | 1 |
Bressel, M; Kastendieck, H; Klein, H; Voigt, KD | 1 |
Al-Sarraf, M; Decker, DA; Kresge, C; Subramanian, MG; Tapazoglou, E | 1 |
Amery, W; Beerens, D; Caers, I; Coene, MC; De Coster, R; Haelterman, C | 1 |
Carlström, K; Eriksson, A; Henriksson, P; Stege, R | 1 |
Trachtenberg, J; Zadra, J | 1 |
Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F | 1 |
Dowsett, M; Jeffcoate, SL; Malone, P; Ponder, BA; Shearer, RJ | 1 |
Ahmann, FR; Crawford, ED; Kreis, W; Levasseur, Y | 1 |
Fair, WR; Fishman, J; Laudone, VP; Stone, NN | 1 |
Berg, AA; Daehlin, L; Damber, JE; Hammar, M; Petersson, F | 1 |
Marts, SA; Padilla, GM; Petrow, V | 1 |
Allen, J; Bloom, SR; Doble, A; Dunlop, H; Kerle, DJ; Smith, C; Ware, H; Williams, G; Yeo, T | 1 |
Chaban, M; Denis, L; Mahler, C | 1 |
Bertagna, C; Coussedière, D; Husson, JM; Moguilewsky, M; Pendyala, L; Pottier, J; Raynaud, JP; Salmon, J; Tournemine, C; Tremblay, D | 1 |
Ochiai, K; Oshima, H; Sarada, T; Tamaoki, B | 1 |
Cavazos, LF; Leav, I; Ofner, P | 1 |
Altwein, JE; Hohenfellner, R; Orestano, F | 1 |
9 review(s) available for androstenedione and Cancer of Prostate
Article | Year |
---|---|
[Advances in the study of steroidal inhibitors of cytochrome P45017alpha].
Topics: Androstenedione; Androstenes; Androstenols; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Humans; Male; Molecular Structure; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone | 2013 |
11β-hydroxyandrostenedione returns to the steroid arena: biosynthesis, metabolism and function.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Dihydrotestosterone; Humans; Hydroxysteroid Dehydrogenases; Male; Prostatic Neoplasms; Steroid 11-beta-Hydroxylase | 2013 |
[CYP17A1 inhibitors in prostate cancer: mechanisms of action independent of the androgenic pathway].
Topics: Abiraterone Acetate; Adjuvants, Immunologic; Androgens; Androstadienes; Androstenedione; Antineoplastic Agents; Dehydroepiandrosterone; Disease Progression; Humans; Male; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Treatment Outcome | 2013 |
[The alternative androgen synthesis pathway in humans].
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Glands; Adrenal Hyperplasia, Congenital; Androgens; Androstenedione; Animals; Child; Child, Preschool; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Infant; Infant, Newborn; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Pregnancy; Prostatic Neoplasms; Sex Differentiation; Steroid 21-Hydroxylase; Testis; Testosterone | 2013 |
Oral andro-related prohormone supplementation: do the potential risks outweigh the benefits?
Topics: Androstenediol; Androstenediols; Androstenedione; Dietary Supplements; Estrogens; Humans; Lipoproteins, HDL; Male; Muscle, Skeletal; Prostatic Neoplasms; Risk Factors; Sexual Behavior; Testosterone | 2003 |
Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies.
Topics: Aged; Androgens; Androstenediols; Androstenedione; Case-Control Studies; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estradiol; Glucuronides; Gonadal Steroid Hormones; Humans; Logistic Models; Male; Middle Aged; Prostatic Neoplasms; Research Design; Risk Assessment; Risk Factors; Sex Hormone-Binding Globulin; Testosterone | 2008 |
Formestane. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the management of breast cancer and prostatic cancer.
Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; In Vitro Techniques; Male; Prostatic Neoplasms | 1993 |
Androgen binding and metabolism in the human prostate.
Topics: Androgens; Androstanes; Androstenedione; Animals; Cytosol; Dihydrotestosterone; Humans; Male; Muscles; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Protein Binding; Rats; Receptors, Cell Surface; Testosterone | 1975 |
Aromatase and other inhibitors in breast and prostatic cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Humans; Male; Prostatic Neoplasms | 1990 |
13 trial(s) available for androstenedione and Cancer of Prostate
Article | Year |
---|---|
Extragonadal Steroids Contribute Significantly to Androgen Receptor Activity and Development of Castration Resistance in Recurrent Prostate Cancer after Primary Therapy.
Topics: Anabolic Agents; Androgens; Androstenedione; Biomarkers, Tumor; Castration; Cell Line, Tumor; Follow-Up Studies; Humans; Male; Mass Spectrometry; Neoplasm Recurrence, Local; Prospective Studies; Prostate; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Time Factors | 2020 |
Effect of finasteride on serum levels of androstenedione, testosterone and their 5α-reduced metabolites in men at risk for prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Aged; Androstane-3,17-diol; Androstenedione; Dihydrotestosterone; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone | 2013 |
Effect of finasteride on serum androstenedione and risk of prostate cancer within the prostate cancer prevention trial: differential effect on high- and low-grade disease.
Topics: Androstenedione; Case-Control Studies; Double-Blind Method; Finasteride; Humans; Male; Middle Aged; Neoplasm Grading; Prostatic Neoplasms; Risk Assessment | 2015 |
A Randomized Control Trial Comparing the Efficacy of Antiandrogen Monotherapy: Flutamide vs. Bicalutamide.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenedione; Anilides; Dehydroepiandrosterone; Flutamide; Humans; Male; Neoplasm Staging; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone; Tosyl Compounds | 2015 |
17α-alkynyl 3α, 17β-androstanediol non-clinical and clinical pharmacology, pharmacokinetics and metabolism.
Topics: Administration, Oral; Androstanols; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Biotransformation; Cell Line, Tumor; Chromatography, Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dogs; Drug Administration Schedule; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Macaca fascicularis; Male; Metabolomics; Mice; Microsomes, Liver; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Species Specificity; Tandem Mass Spectrometry; Testosterone; Transcriptional Activation; Transfection | 2012 |
Endogenous sex hormones and the risk of prostate cancer: a prospective study.
Topics: Aged; Androstenedione; Case-Control Studies; Cohort Studies; Gonadal Steroid Hormones; Humans; Male; Middle Aged; Odds Ratio; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Sex Hormone-Binding Globulin; Surveys and Questionnaires; Testosterone | 2008 |
A case for synchronous reduction of testicular androgen, adrenal androgen and prolactin for the treatment of advanced carcinoma of the prostate.
Topics: Androgen Antagonists; Androstenedione; Bromocriptine; Humans; Hydrocortisone; Male; Orchiectomy; Prolactin; Prospective Studies; Prostatic Neoplasms; Treatment Outcome | 1995 |
Effect of the nonsteroidal antiandrogen nilutamide on adrenal androgen secretion.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aged; Androgen Antagonists; Androgens; Androstenedione; Antineoplastic Agents; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Imidazoles; Imidazolidines; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Triptorelin Pamoate | 1994 |
Effects of long-term alpha-tocopherol supplementation on serum hormones in older men.
Topics: Alcohol Drinking; Androstenedione; Cholesterol; Dehydroepiandrosterone; Eating; Follow-Up Studies; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Prolactin; Prostatic Neoplasms; Radioimmunoassay; Regression Analysis; Sex Hormone-Binding Globulin; Smoking; Testosterone; Vitamin E | 2001 |
Aromatase inhibition: 4-hydroxyandrostenedione (4-OHA, CGP 32349) in advanced prostatic cancer.
Topics: Aged; Androstenedione; Aromatase Inhibitors; Dihydrotestosterone; Estradiol; Humans; Male; Neoplasm Staging; Prostatic Neoplasms; Testosterone; Time Factors | 1992 |
Pituitary adrenal and gonadal endocrine suppression for the primary treatment of prostate cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenedione; Cyproterone; Cyproterone Acetate; Dexamethasone; Humans; Hydrocortisone; Luteinizing Hormone; Male; Middle Aged; Orchiectomy; Prospective Studies; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Testosterone | 1990 |
Adrenocortical function in prostatic cancer patients: effects of orchidectomy or different modes of estrogen treatment on basal steroid levels and on the response to exogenous adrenocorticotropic hormone.
Topics: 17-alpha-Hydroxyprogesterone; Administration, Oral; Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; Combined Modality Therapy; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Estradiol; Estradiol Congeners; Ethinyl Estradiol; Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Injections, Intramuscular; Male; Orchiectomy; Prostatic Neoplasms; Serum Albumin; Steroid 16-alpha-Hydroxylase; Testosterone | 1990 |
Aromatase inhibition in advanced prostatic cancer: preliminary communication.
Topics: Aged; Aged, 80 and over; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Clinical Trials as Topic; Humans; Male; Middle Aged; Prostatic Neoplasms | 1990 |
107 other study(ies) available for androstenedione and Cancer of Prostate
Article | Year |
---|---|
Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3.
Topics: 17-Hydroxysteroid Dehydrogenases; Androgens; Animals; Carbamates; Cell Line, Tumor; Drug Design; Enzyme Inhibitors; Humans; Male; Morpholines; Prostate; Prostatic Neoplasms; Rats; Spiro Compounds | 2015 |
Sex steroid hormones in urinary exosomes as biomarkers for the prediction of prostate cancer.
Topics: Androstenedione; Biomarkers; Dehydroepiandrosterone; Dihydrotestosterone; Exosomes; Humans; Male; Prostatic Neoplasms; Tandem Mass Spectrometry; Testosterone | 2022 |
Extensive Alteration of Androgen Precursor Levels After Castration in Prostate Cancer Patients and Their Association With Active Androgen Level.
Topics: Androgen Antagonists; Androgens; Androstenedione; Androsterone; Dehydroepiandrosterone; Dihydrotestosterone; Estrone; Humans; Male; Orchiectomy; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sulfates; Testosterone | 2022 |
3βHSD activity saturates at physiological substrate concentrations in intact cells.
Topics: Androgens; Androstenediols; Androstenedione; Cell Line, Tumor; Dehydroepiandrosterone; Humans; Male; Placenta; Pregnancy; Prostatic Neoplasms | 2023 |
Plasma Androstenedione Concentration Can Discriminate Frail versus Non-Frail Men with Prostate Cancer under Androgen Deprivation Therapy.
Topics: Aged; Androgen Antagonists; Androgens; Androstenedione; Dehydroepiandrosterone; Frail Elderly; Frailty; Humans; Male; Prostatic Neoplasms; Testosterone | 2023 |
Steroidogenesis in Peripheral and Transition Zones of Human Prostate Cancer Tissue.
Topics: Androstenedione; Androsterone; Chromatography, High Pressure Liquid; Humans; Male; Mass Spectrometry; Progesterone; Prostate; Prostatic Neoplasms; Steroids; Testosterone | 2021 |
Innovative C
Topics: Androstenedione; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Dimerization; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Male; Molecular Structure; Prostatic Neoplasms; Recombinant Proteins; Structure-Activity Relationship; Testosterone; Tumor Cells, Cultured | 2021 |
Angela M. Hartley Brodie (1934-2017).
Topics: Androstadienes; Androstenedione; Aromatase Inhibitors; Benzimidazoles; Breast Neoplasms; Estrogens; Female; History, 20th Century; History, 21st Century; Humans; Male; Maryland; Prostatic Neoplasms | 2017 |
AR Signaling in Prostate Cancer Regulates a Feed-Forward Mechanism of Androgen Synthesis by Way of HSD3B1 Upregulation.
Topics: Androgens; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Benzamides; Cell Line, Tumor; Dehydroepiandrosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Metribolone; Mice; Multienzyme Complexes; Neoplasm Transplantation; Nitriles; Orchiectomy; Phenylthiohydantoin; Progesterone Reductase; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Steroid Isomerases; Testosterone; Testosterone Congeners; Up-Regulation | 2018 |
11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Androstenedione; Cell Line, Tumor; Cortodoxone; HEK293 Cells; Humans; Hydroxyprogesterones; Male; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase | 2019 |
Human castration resistant prostate cancer rather prefer to decreased 5α-reductase activity.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Carbon Isotopes; Castration; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Coculture Techniques; Dihydrotestosterone; Humans; Male; Membrane Proteins; Prostatic Neoplasms; RNA, Messenger; Tandem Mass Spectrometry; Testosterone | 2013 |
Studying the connection between exercise and cancer risk reduction.
Topics: Androstenedione; Biomarkers; Breast Neoplasms; Colonic Neoplasms; Diet, Reducing; Endometrial Neoplasms; Estrogens; Exercise; Female; Humans; Inflammation; Male; Motor Activity; Neoplasms; Obesity; Ovarian Neoplasms; Physical Exertion; Prostatic Neoplasms; Risk Assessment; Risk Factors; Risk Reduction Behavior; Sex Hormone-Binding Globulin | 2013 |
TGFβ1 alters androgenic metabolites and hydroxysteroid dehydrogenase enzyme expression in human prostate reactive stromal primary cells: Is steroid metabolism altered by prostate reactive stromal microenvironment?
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Cell Line, Tumor; Dehydroepiandrosterone; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxysteroid Dehydrogenases; Male; Prostate; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Stromal Cells; Testosterone; Transforming Growth Factor beta1 | 2013 |
Re: effect of finasteride on serum levels of androstenedione, testosterone and their 5α-reduced metabolites in men at risk for prostate cancer.
Topics: 5-alpha Reductase Inhibitors; Androstenedione; Finasteride; Humans; Male; Prostatic Neoplasms; Testosterone | 2013 |
Response to commentary.
Topics: 5-alpha Reductase Inhibitors; Androstenedione; Finasteride; Humans; Male; Prostatic Neoplasms; Testosterone | 2013 |
Pomegranate extracts impact the androgen biosynthesis pathways in prostate cancer models in vitro and in vivo.
Topics: Androgens; Androstenedione; Animals; Blotting, Western; Cell Proliferation; Dihydrotestosterone; Humans; In Vitro Techniques; Lythraceae; Male; Mice; Mice, Knockout; Plant Extracts; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; PTEN Phosphohydrolase; Receptors, Androgen; Testosterone; Tumor Cells, Cultured | 2014 |
Canonical androstenedione reduction is the predominant source of signaling androgens in hormone-refractory prostate cancer.
Topics: 3-Hydroxysteroid Dehydrogenases; Aged; Aged, 80 and over; Aldo-Keto Reductase Family 1 Member C3; Androgens; Androstenedione; Estradiol Dehydrogenases; Humans; Hydroxyprostaglandin Dehydrogenases; Male; Middle Aged; Prostate; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Up-Regulation | 2014 |
In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3).
Topics: Administration, Oral; Androstenedione; Animals; Biological Availability; Cell Line, Tumor; Dogs; Enzyme Inhibitors; Estradiol Dehydrogenases; Humans; Indoles; Macaca fascicularis; Male; Mice, Inbred BALB C; Piperidines; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone | 2014 |
Hormone whodunit: clues for solving the case of intratumor androgen production.
Topics: Androgens; Androstenedione; Humans; Male; Prostatic Neoplasms | 2014 |
Androstenedione is the preferred androgen source in hormone refractory prostate cancer--letter.
Topics: Androgen Antagonists; Androgens; Androstenedione; Drug Resistance, Neoplasm; Humans; Male; Prostatic Neoplasms | 2014 |
Androstenedione is the preferred androgen source in hormone refractory prostate cancer--response.
Topics: Androgens; Androstenedione; Drug Resistance, Neoplasm; Humans; Male; Prostatic Neoplasms | 2014 |
Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry.
Topics: 5-alpha Reductase Inhibitors; Androgens; Androstenedione; Azasteroids; Chromatography, Liquid; Dihydrotestosterone; Dutasteride; Finasteride; Humans; Male; Prostatic Neoplasms; Solid Phase Extraction; Tandem Mass Spectrometry; Testosterone; Tissue Distribution | 2015 |
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer.
Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Aged, 80 and over; Aldo-Keto Reductase Family 1 Member C3; Androgens; Androstenedione; Animals; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Hydroxyprostaglandin Dehydrogenases; Male; Mice; Middle Aged; Neoplasms, Experimental; Orchiectomy; Pregnenolone; Progesterone Reductase; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Testosterone; Transplantation, Heterologous | 2010 |
Effect of castration monotherapy on the levels of adrenal androgens in cancerous prostatic tissues.
Topics: Adrenal Glands; Androgens; Androstenediol; Androstenedione; Castration; Chromatography, Liquid; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Prostate; Prostatic Neoplasms | 2011 |
The association between inflammation-related genes and serum androgen levels in men: the prostate, lung, colorectal, and ovarian study.
Topics: Aged; Alleles; Androgens; Androstenedione; Case-Control Studies; Gene Frequency; Genetic Association Studies; Genotype; Humans; Inflammation; Male; Middle Aged; Polymorphism, Single Nucleotide; Prostatic Neoplasms; Testosterone | 2012 |
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors.
Topics: Androstenedione; Androstenes; Androstenols; Animals; Antineoplastic Agents, Hormonal; Carcinoma; Cell Line, Tumor; Dehydroepiandrosterone; Female; Humans; Indomethacin; Male; Mice; Orchiectomy; Pregnenolone; Progesterone; Prostatic Neoplasms; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Up-Regulation | 2011 |
Lower testosterone levels with luteinizing hormone-releasing hormone agonist therapy than with surgical castration: new insights attained by mass spectrometry.
Topics: Aged; Aged, 80 and over; Androstenedione; Castration; Chromatography, Liquid; Dehydroepiandrosterone Sulfate; Gonadotropin-Releasing Hormone; Humans; Male; Middle Aged; Prostatic Neoplasms; Retrospective Studies; Sex Hormone-Binding Globulin; Tandem Mass Spectrometry; Testosterone | 2012 |
Abiraterone inhibits 3β-hydroxysteroid dehydrogenase: a rationale for increasing drug exposure in castration-resistant prostate cancer.
Topics: 3-Hydroxysteroid Dehydrogenases; Abiraterone Acetate; Active Transport, Cell Nucleus; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Cell Line, Tumor; Dehydroepiandrosterone; Dihydrotestosterone; Drug Resistance, Neoplasm; Humans; Isoenzymes; Male; Mice; Mice, Inbred NOD; Mice, SCID; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Development of prostate cancer in a patient with primary hypogonadism: intratumoural steroidogenesis in prostate cancer tissues.
Topics: Aged; Androstenedione; Dihydrotestosterone; Disease Progression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Hypogonadism; Immunohistochemistry; Male; Orchiectomy; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone | 2013 |
Endogenous sex hormones and prostate cancer risk: a case-control study nested within the Carotene and Retinol Efficacy Trial.
Topics: Age Distribution; Aged; Androstenedione; Antioxidants; Biomarkers, Tumor; Carotenoids; Case-Control Studies; Confidence Intervals; Estradiol; Gonadal Steroid Hormones; Humans; Incidence; Male; Middle Aged; Odds Ratio; Probability; Prostate-Specific Antigen; Prostatic Neoplasms; Radioimmunoassay; Reference Values; Risk Assessment; Sensitivity and Specificity; Sex Hormone-Binding Globulin; Testosterone; Vitamin A | 2003 |
The androgen axis in recurrent prostate cancer.
Topics: Aged; Aged, 80 and over; Androgens; Androstenedione; Antibodies, Monoclonal; Cell Nucleus; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Microscopy, Video; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Radioimmunoassay; Receptors, Androgen; Recurrence | 2004 |
Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol.
Topics: Adaptor Proteins, Signal Transducing; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Androstenediol; Androstenedione; Anilides; Animals; Breast Neoplasms; Carrier Proteins; Cell Division; Chlorocebus aethiops; COS Cells; Cyproterone Acetate; Dihydrotestosterone; Humans; Ligands; Macaca mulatta; Male; Mammary Tumor Virus, Mouse; Mice; Nerve Tissue Proteins; Nitriles; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, AMPA; Receptors, Androgen; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured | 2004 |
Serum sex steroid hormone levels and polymorphisms of CYP17 and SRD5A2: implication for prostate cancer risk.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Aged, 80 and over; Androgens; Androstenedione; Biomarkers, Tumor; Cohort Studies; DNA, Neoplasm; Genotype; Humans; Japan; Male; Middle Aged; Polymorphism, Genetic; Prostatic Neoplasms; Risk Factors; Steroid 17-alpha-Hydroxylase; Testosterone | 2004 |
Identification of novel functional inhibitors of 17beta-hydroxysteroid dehydrogenase type III (17beta-HSD3).
Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Anti-Inflammatory Agents; Drug Evaluation, Preclinical; Glycyrrhetinic Acid; Humans; Male; ortho-Aminobenzoates; Prostatic Neoplasms; Testosterone | 2005 |
Getting over testosterone: postulating a fresh start for etiologic studies of prostate cancer.
Topics: Androgens; Androstenediols; Androstenedione; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estradiol; Glucuronides; Gonadal Steroid Hormones; Humans; Male; Meta-Analysis as Topic; Prostatic Neoplasms; Research Design; Risk Factors; Testosterone | 2008 |
Evaluation of androgen metabolism studies in human prostate cancer--correlation with zinc levels.
Topics: Aged; Androgens; Androstenedione; Carcinoma; Dihydrotestosterone; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone; Zinc | 1980 |
Altered androgen metabolism in carcinoma of the prostate.
Topics: Androstenediols; Androstenedione; Culture Techniques; Dihydrotestosterone; Male; Oxidation-Reduction; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1981 |
Response to aminoglutethimide and cortisone acetate in advanced prostatic cancer.
Topics: Adenocarcinoma; Aged; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Cortisone; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Middle Aged; Prostatic Neoplasms; Sleep Stages; Testosterone | 1984 |
Ketoconazole therapy in advanced prostatic cancer.
Topics: Acid Phosphatase; Aged; Androstenedione; Dehydroepiandrosterone; Follow-Up Studies; Humans; Ketoconazole; Male; Prostatic Neoplasms; Testosterone; Time Factors | 1984 |
Long-term effects of endocrine treatment on serum steroids in advanced prostatic carcinoma patients.
Topics: Aged; Androstenedione; Androsterone; Castration; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Middle Aged; Organophosphorus Compounds; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroids; Testosterone | 1980 |
Androgen metabolism by human prostatic tumours in organ culture.
Topics: Androstenedione; Dihydrotestosterone; Humans; Male; NADPH Dehydrogenase; Organ Culture Techniques; Oxidation-Reduction; Prostatic Neoplasms; Testosterone | 1983 |
Effect of the preestrogen 4-androstene-3,17-dion-19-al on the Dunning R3327 prostatic adenocarcinoma.
Topics: Adenocarcinoma; Androstenedione; Animals; Diethylstilbestrol; Estradiol; Male; Organ Size; Prostate; Prostatic Neoplasms; Rats | 1983 |
Testosterone and some of its precursors and metabolites in the human epididymis.
Topics: Aged; Androstane-3,17-diol; Androstenedione; Androsterone; Dihydrotestosterone; Epididymis; Estrogens; Humans; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis; Testosterone; Vas Deferens | 1980 |
Basis for hormonal management of advanced prostate cancer.
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Protein Biosynthesis; Rats; Testosterone | 1993 |
Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone.
Topics: Adrenal Glands; Aged; Amino Acid Sequence; Androgen Antagonists; Androstenedione; Animals; Base Sequence; Carcinoma; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Dehydroepiandrosterone; Dihydrotestosterone; DNA, Complementary; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Gonadal Steroid Hormones; Humans; Male; Molecular Sequence Data; Neoplasm Proteins; Point Mutation; Polymerase Chain Reaction; Progesterone; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Steroids; Transcriptional Activation | 1993 |
Testicular androgens in prostate cancer patients treated with a luteinizing hormone releasing hormone agonist.
Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Aged, 80 and over; Androgens; Androstenedione; Humans; Leuprolide; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Testis; Testosterone | 1994 |
Serum pituitary and sex steroid hormone levels in the etiology of prostatic cancer--a population-based case-control study.
Topics: Age Factors; Aged; Androstenedione; Case-Control Studies; Estradiol; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Neoplasm Staging; Prostatic Neoplasms; Registries; Sex Hormone-Binding Globulin; Sweden; Testosterone | 1993 |
In vitro studies on the inhibition of testosterone synthesis in the human testis by atamestane.
Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Androstenedione; Binding, Competitive; Humans; In Vitro Techniques; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Testis; Testosterone | 1993 |
Testosterone metabolism in primary cultures of human prostate epithelial cells and fibroblasts.
Topics: 17-Hydroxysteroid Dehydrogenases; Adenosarcoma; Androstenedione; Azasteroids; Blotting, Northern; Cells, Cultured; Cholestenone 5 alpha-Reductase; Chromatography, High Pressure Liquid; Dihydrotestosterone; Enzyme Inhibitors; Epithelium; Etiocholanolone; Fibroblasts; Finasteride; Humans; Male; Meningioma; Oxidoreductases; Placenta; Prostatic Neoplasms; RNA; RNA, Messenger; Testosterone; Tumor Cells, Cultured | 1995 |
Inhibition of aromatase activity and growth suppression by 4-methoxy-4-androstene-3,17-dione in an androgen sensitive human prostatic carcinoma cell line.
Topics: Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Cell Division; Culture Media, Serum-Free; Drug Screening Assays, Antitumor; Humans; Male; Prostatic Neoplasms; Testosterone; Tumor Cells, Cultured | 1996 |
Activation of two mutant androgen receptors from human prostatic carcinoma by adrenal androgens and metabolic derivatives of testosterone.
Topics: Androgens; Androstenedione; Androsterone; Animals; Base Sequence; Blood Proteins; Complement C4; DNA, Neoplasm; Haplorhini; Humans; Male; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Testosterone; Transcriptional Activation; Transfection | 1996 |
Effect of turosteride, a 5 alpha-reductase inhibitor, on the Dunning R3327 rat prostatic carcinoma.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Leuprolide; Luteinizing Hormone; Male; Organ Size; Pituitary Gland, Anterior; Prostate; Prostatic Neoplasms; Random Allocation; Rats; Seminal Vesicles; Testis; Testosterone | 1997 |
Functional characterization of mutant androgen receptors from androgen-independent prostate cancer.
Topics: Amino Acid Substitution; Androgen Antagonists; Androgens; Androstenedione; Animals; beta-Galactosidase; Cell Line; Dihydrotestosterone; Estradiol; Flutamide; Genes, Reporter; Imidazoles; Imidazolidines; Luciferases; Male; Point Mutation; Progesterone; Prostatic Neoplasms; Receptors, Androgen; Recombinant Fusion Proteins; Transfection | 1997 |
Serum testosterone and sex hormone-binding globulin concentrations and the risk of prostate carcinoma: a longitudinal study.
Topics: Aged; Androstenedione; Biomarkers, Tumor; Carcinoma; Case-Control Studies; Humans; Longitudinal Studies; Male; Middle Aged; Prognosis; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Testosterone | 1999 |
5alpha-reductase isozymes and aromatase are differentially expressed and active in the androgen-independent human prostate cancer cell lines DU145 and PC3.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Anastrozole; Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Blotting, Southern; Dihydrotestosterone; Enzyme Inhibitors; Etiocholanolone; Humans; Hydrogen-Ion Concentration; Isoenzymes; Male; Microsomes; Nitriles; Prostatic Hyperplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone; Triazoles; Tumor Cells, Cultured | 1999 |
Antiandrogens fail to block androstenedione-mediated mutated androgen receptor transactivation in human prostate cancer cells.
Topics: Androgen Antagonists; Androstenedione; Humans; Male; Mutation; Prostatic Neoplasms; Receptors, Androgen; Transcriptional Activation; Tumor Cells, Cultured | 2000 |
Inhibitors of human and rat testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD) as potential agents for prostatic cancer.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Benzoquinones; Drug Evaluation, Preclinical; Enzyme Inhibitors; Estradiol; Estrone; Flavanones; Flavonoids; Genistein; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Kinetics; Male; Microsomes; Prostatic Neoplasms; Rats; Structure-Activity Relationship; Testis; Testosterone | 2001 |
Letter: Hormones, elderly testes, and carcinoma of the prostate.
Topics: Androgens; Androstenedione; Dihydrotestosterone; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1975 |
Androgen levels in the plasma and prostatic tissues of patients with benign hypertrophy and carcinoma of the prostate.
Topics: Aged; Androgens; Androstenedione; Dihydrotestosterone; Humans; Male; Middle Aged; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1976 |
Androgen receptors in male sex tissues of rats and humans.
Topics: Androstane-3,17-diol; Androstenedione; Animals; Dihydrotestosterone; Epididymis; Humans; Male; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Steroid; Testis; Testosterone | 1976 |
The influence of oestradiol on the metabolism of androgens by human prostatic tissue.
Topics: Aged; Androgens; Androstenedione; Dihydrotestosterone; Estradiol; Humans; Male; Middle Aged; Organ Culture Techniques; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1977 |
Serum steroids in normal males and patients with prostatic diseases.
Topics: Adult; Aged; Aging; Androstenedione; Androsterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Hyperplasia; Prostatic Neoplasms; Reference Values; Steroids; Testosterone | 1978 |
Conversion of androstenedione to estrone in human fibroblasts cultured from prostate, genital and nongenital skin.
Topics: Adolescent; Adult; Aged; Androstenedione; Cells, Cultured; Estrone; Fibroblasts; Humans; Kinetics; Male; Middle Aged; Penis; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Skin | 1979 |
Suppression of plasma androgens by spironolactone in castrated men with carcinoma of the prostate.
Topics: Aged; Androgens; Androstenedione; Castration; Dehydroepiandrosterone; Depression, Chemical; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Spironolactone; Testosterone | 1975 |
Biosynthesis and metabolism of androgenic hormones in cancer of the prostate.
Topics: Adenocarcinoma; Androgens; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Prostatic Neoplasms; Testosterone | 1976 |
The effect of ACTH on plasma testosterone and androstenedione concentrations in patients with prostatic carcinoma.
Topics: Adrenocorticotropic Hormone; Androstenedione; Cosyntropin; Cross Reactions; Diethylstilbestrol; Humans; Male; Prostatic Neoplasms; Stimulation, Chemical; Testosterone | 1976 |
Metabolism of testosterone in the human prostate and seminal vesicles.
Topics: Adenocarcinoma; Androstanes; Androstenedione; Androsterone; Culture Techniques; Humans; Hyperplasia; Male; Prostate; Prostatic Neoplasms; Seminal Vesicles; Testosterone | 1977 |
In vitro steroid metabolic studies in human testes. II: Metabolism of cholesterol, pregnenolone, progesterone, androstenedione and testosterone by testes of an estrogen-treated man.
Topics: Adult; Androgens; Androstenedione; Cholesterol; Estradiol Congeners; Estrogens; Ethinyl Estradiol; Humans; Male; Pregnenolone; Progesterone; Progestins; Prostatic Neoplasms; Testis; Testosterone; Transsexualism | 1977 |
C19-steroid metabolism by spontaneous adenocarcinoma of the A X C rat ventral prostate.
Topics: 17-Ketosteroids; Adenocarcinoma; Androstenedione; Animals; Dihydrotestosterone; Hydroxysteroids; Hyperplasia; Male; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Testosterone | 1977 |
Correlative study of the morphology and C19-steroid metabolism of benign and cancerous human prostatic tissue.
Topics: Androgens; Androstane-3,17-diol; Androstenedione; Carcinoma, Transitional Cell; Dihydrotestosterone; Humans; Hyperplasia; In Vitro Techniques; Male; Prostate; Prostatic Neoplasms; Testosterone | 1977 |
The simultaneous radioimmunoassay of seven steroids in human spermatic and peripheral venous blood.
Topics: Adult; Aged; Androstenedione; Androsterone; Dihydrotestosterone; Hormones; Humans; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Radioimmunoassay; Steroids; Testis; Testosterone | 1977 |
Intratesticular site of aromatization in the human.
Topics: Adult; Aged; Androstenedione; Estradiol; Estrone; Humans; Infant; Male; Middle Aged; Prostatic Neoplasms; Testis; Testosterone | 1976 |
Plasma steroid and protein hormone concentrations in patients with prostatic carcinoma, before and during oestrogen therapy.
Topics: Aged; Androstenedione; Carcinoma; Estradiol; Follicle Stimulating Hormone; Growth Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Prolactin; Prostatic Neoplasms; Steroids; Testosterone | 1976 |
A method for tissue extraction and determination of prostate concentrations of endogenous androgens by radioimmunoassay.
Topics: Androgens; Androstane-3,17-diol; Androstenedione; Dihydrotestosterone; Humans; Kidney; Male; Methods; Prostate; Prostatic Neoplasms; Radioimmunoassay; Spleen; Testosterone | 1976 |
Identification of 4-hydroxyandrost-4-ene-3,17-dione metabolites in prostatic cancer patients by liquid chromatography-mass spectrometry.
Topics: Androstenedione; Chromatography, High Pressure Liquid; Humans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Prostatic Neoplasms; Spectrophotometry, Ultraviolet | 1992 |
Effects of adrenal androgens on the transplantable human prostate tumor PC-82.
Topics: Androstenedione; Animals; Bromodeoxyuridine; Cell Division; Dehydroepiandrosterone; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Orchiectomy; Prostatic Neoplasms; Testosterone; Tumor Cells, Cultured | 1992 |
Comparison of the nuclear 5 alpha-reduction of testosterone and androstenedione in human prostatic carcinoma and benign prostatic hyperplasia.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Cell Fractionation; Cell Nucleus; Humans; Kinetics; Male; NADP; Oxidation-Reduction; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1990 |
Comparison of aromatase activity in human prostatic, testicular and placental tissues.
Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Carcinoma; Female; Humans; Male; Microsomes; Placenta; Pregnancy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Testis; Tissue Distribution | 1991 |
Effect of suramin on human prostate cancer cells in vitro.
Topics: Adenocarcinoma; Androstenedione; Antineoplastic Agents; Cell Line; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; In Vitro Techniques; Male; Prostatic Neoplasms; Suramin; Tumor Cells, Cultured | 1991 |
Pharmacia Award 1990. The biological significance of low testosterone levels and of adrenal androgens in transplantable prostate cancer lines.
Topics: Adenocarcinoma; Androstenedione; Animals; Awards and Prizes; Castration; Dehydroepiandrosterone; Europe; Humans; Male; Mice; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Societies, Medical; Testosterone; Urology | 1991 |
Growth-stimulating effect of adrenal androgens on the R3327 Dunning prostatic carcinoma.
Topics: Adenocarcinoma; Androstenedione; Animals; Castration; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Male; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1991 |
Steroid glucuronides: human circulatory levels and formation by LNCaP cells.
Topics: Adolescent; Adult; Aging; Androstane-3,17-diol; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Glucuronates; Humans; Male; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Sulfates; Tumor Cells, Cultured | 1991 |
Suppression of plasma androgens by the antiandrogen flutamide in prostatic cancer patients treated with Zoladex, a GnRH analogue.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androgens; Androstenedione; Anilides; Antineoplastic Agents; Buserelin; Dehydroepiandrosterone; Depression, Chemical; Flutamide; Goserelin; Humans; Hydroxyprogesterones; Male; Orchiectomy; Prostatic Neoplasms; Testosterone | 1990 |
A prospective, population-based study of androstenedione, estrogens, and prostatic cancer.
Topics: Adult; Aged; Androstenedione; California; Cohort Studies; Estradiol; Estrone; Humans; Male; Middle Aged; Prospective Studies; Prostatic Neoplasms; Reference Values; Risk Factors; Sex Hormone-Binding Globulin; Surveys and Questionnaires; Testosterone | 1990 |
New approaches for the treatment of prostatic hypertrophy and cancer.
Topics: Aged; Androgens; Androstenedione; Animals; Carbon Radioisotopes; Humans; Kinetics; Male; Middle Aged; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Rats, Inbred Strains | 1987 |
High-dose ketoconazole in advanced hormone-refractory prostate cancer: endocrinologic and clinical effects.
Topics: Acid Phosphatase; Aged; Aged, 80 and over; Androstenedione; Antigens, Neoplasm; Biomarkers, Tumor; Diethylstilbestrol; Drug Evaluation; Humans; Hydrocortisone; Ketoconazole; Male; Middle Aged; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Testicular Hormones; Testosterone | 1989 |
Lack of evidence for aromatase in human prostatic tissues: effects of 4-hydroxyandrostenedione and other inhibitors on androgen metabolism.
Topics: Androstenedione; Aromatase; Cholestenone 5 alpha-Reductase; Estrogens; Humans; In Vitro Techniques; Male; Oxidoreductases; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1989 |
A comparison of androgen status in patients with prostatic cancer treated with oral and/or parenteral estrogens or by orchidectomy.
Topics: Administration, Oral; Aged; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrogens; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Testosterone | 1989 |
Decreased urinary 5 alpha-androstane-3 alpha,17 beta-diol glucuronide excretion in patients with benign prostatic hyperplasia.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aging; Androstane-3,17-diol; Androstanols; Androstenedione; Dihydrotestosterone; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1985 |
Androgens, adrenal androgen precursors, and their metabolism in untreated primary tumors and lymph node metastases of human prostatic cancer.
Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Glands; Androgens; Androstenediols; Androstenedione; Arylsulfatases; Cholestenone 5 alpha-Reductase; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Humans; Lymphatic Metastasis; Male; Neoplasms, Hormone-Dependent; Oxidoreductases; Prostate; Prostatic Neoplasms; Steryl-Sulfatase; Testosterone | 1988 |
High-dose ketoconazole therapy in patients with metastatic prostate cancer.
Topics: Adenocarcinoma; Aged; Androstenedione; Combined Modality Therapy; Dehydroepiandrosterone; Dexamethasone; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Humans; Ketoconazole; Luteinizing Hormone; Male; Middle Aged; Neoplasm Metastasis; Orchiectomy; Prostatic Neoplasms; Testosterone | 1986 |
Effects of high dose ketoconazole therapy on the main plasma testicular and adrenal steroids in previously untreated prostatic cancer patients.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Aged; Androgens; Androstenedione; Corticosterone; Cortodoxone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Testosterone | 1986 |
Orchidectomy or oestrogen treatment in prostatic cancer: effects on serum levels of adrenal androgens and related steroids.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Aged; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrogens; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Serum Albumin; Steroids | 1987 |
Steroid synthesis inhibition by ketoconazole: sites of action.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aldehyde-Lyases; Androgens; Androstenedione; Chorionic Gonadotropin; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone | 1988 |
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Anilides; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dehydroepiandrosterone; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Kinetics; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Prolactin; Prostatic Neoplasms; Testosterone; Triptorelin Pamoate | 1988 |
The effects of aminoglutethimide and hydrocortisone, alone and combined, on androgen levels in post-orchiectomy prostatic cancer patients.
Topics: Aged; Aged, 80 and over; Aminoglutethimide; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Humans; Hydrocortisone; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Testosterone; Time Factors | 1988 |
Adrenal steroid levels in castrated men with prostatic carcinoma treated with aminoglutethimide plus hydrocortisone.
Topics: Aminoglutethimide; Androgens; Androstenedione; Drug Therapy, Combination; Humans; Hydrocortisone; Male; Orchiectomy; Prostatic Neoplasms; Testosterone | 1987 |
Aromatization of androstenedione to estrogen by benign prostatic hyperplasia, prostate cancer and expressed prostatic secretions.
Topics: Androstenedione; Carrier Proteins; Dose-Response Relationship, Drug; Estrogens; Humans; Hyperplasia; Male; Prostate; Prostatic Neoplasms; Prostatic Secretory Proteins | 1987 |
Effects of oestradiol-17 beta and ethinyl oestradiol on human testicular steroidogenesis in vitro.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androstenedione; Estradiol; Ethinyl Estradiol; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Middle Aged; Orchiectomy; Progesterone; Prostatic Neoplasms; Radioimmunoassay; Testis; Testosterone | 1986 |
Aromatase activity in microsomes from rat ventral prostate and Dunning R3327H rat prostatic adenocarcinoma.
Topics: Adenocarcinoma; Age Factors; Androstenedione; Animals; Aromatase; Estrogens; Male; Microsomes; Prostate; Prostatic Neoplasms; Rats | 1987 |
Objective responses to ketoconazole therapy in patients with relapsed progressive prostatic cancer.
Topics: Acid Phosphatase; Aged; Androstenedione; Humans; Ketoconazole; Male; Middle Aged; Prostatic Neoplasms; Testosterone; Time Factors | 1986 |
Clinical applications of ketoconazole in prostatic cancer.
Topics: Androstenedione; Humans; Ketoconazole; Male; Prostatic Neoplasms; Testosterone | 1985 |
Pharmacology and clinical studies with RU 23908 (Anandron).
Topics: Androgen Antagonists; Androstenedione; Animals; Castration; Diethylstilbestrol; Flutamide; Humans; Imidazoles; Imidazolidines; Kinetics; Male; Organ Size; Prostate; Prostatic Neoplasms; Rats | 1985 |
Effects of a synthetic estrogen upon steroid bioconversion in vitro in testes of patients with prostatic cancer.
Topics: 17-alpha-Hydroxypregnenolone; Administration, Oral; Aged; Androstenedione; Enzyme Repression; Hexestrol; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Lyases; Male; Middle Aged; Mixed Function Oxygenases; NADP; Progesterone; Prostatic Neoplasms; Spermatogenesis; Steroids; Testis; Testosterone | 1974 |
Plasma testosterone and androstenedione after orchiectomy in prostatic adenocarcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenal Glands; Aged; Androstenedione; Castration; Dexamethasone; Humans; Male; Middle Aged; Prostatic Neoplasms; Testis; Testosterone; Time Factors | 1973 |
Fine structure and C19-steroid metabolism of spontaneous adenocarcinoma of the canine prostate.
Topics: 17-Hydroxycorticosteroids; Adenocarcinoma; Androstenedione; Animals; Carbon Radioisotopes; Castration; Dogs; Lymph Nodes; Male; Microscopy, Electron; Neoplasms, Experimental; Organoids; Oxidation-Reduction; Prostate; Prostatic Neoplasms; Testosterone | 1974 |
Testosterone turnover in cancer of the prostate: suppression by gestagens in vitro.
Topics: Androstenediols; Androstenedione; Depression, Chemical; Dihydrotestosterone; Gestonorone Caproate; Humans; In Vitro Techniques; Kinetics; Male; Progesterone; Prostatic Neoplasms; Testosterone; Tritium | 1974 |