Page last updated: 2024-08-21

androstenediol and Breast Neoplasms

androstenediol has been researched along with Breast Neoplasms in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199019 (51.35)18.7374
1990's10 (27.03)18.2507
2000's6 (16.22)29.6817
2010's1 (2.70)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Dallal, CM; Dorgan, JF; Eckert, RL; Jung, S; Snetselaar, LG; Stennett, CA; Van Horn, L; Zhan, M; Zhang, Y1
Harada, N; Hayashi, S; Hirose, M; Honma, N; Horiguchi, S; Kuroi, K; Saji, S; Utsumi, T1
Andò, S; Bonofiglio, D; Carpino, A; Maggiolini, M; Marsico, S; Pezzi, V; Picard, D; Rago, V; Vivacqua, A1
GORDON, D; HORWITT, BN; MURISON, PJ; SCHLOSSER, JV; SEGALOFF, A1
Aspinall, SR; Davison, A; Lennard, TW; Shenton, BK; Stamp, S1
Bai, C; Chen, F; Freedman, L; Gambone, C; Harada, S; Kasparcova, V; Knecht, K; Leu, C; Reszka, A; Rutledge, SJ; Scafonas, A; Schmidt, A; Vogel, R; Zhang, H1
Coombes, RC; Dobbs, N; Elliott, M; Kulinskaya, E; Potter, BV; Purohit, A; Reed, MJ; Stanczyk, FZ; Stanway, SJ; Sufi, S; Vigushin, D; Ward, R; Wilson, RH; Woo, LW1
Adly, L; Fears, T; Hill, D; Hoover, RN; Mies, C; Schairer, C; Sherman, ME; Sturgeon, SR; Ziegler, RG1
Beranek, PA; Bonney, RC; James, VH; Jones, DL; Reed, MJ; Scanlon, MJ1
Bird, CE; Clark, AF; Masters, V; Sterns, EE1
Adams, JB; Archibald, L; Seymour-Munn, K1
Adams, J; Garcia, M; Rochefort, H1
Adams, J; Seymour-Munn, K1
Poortman, J; Rademaker, B; Thijssen, JH; Vossenberg, JB1
Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L; Pizzini, A1
Filmer, A; Hackenberg, R; Schulz, KD; Turgetto, I1
Hackenberg, R; Schulz, KD1
Chang, L; Dorgan, JF; Falk, RT; Franz, C; Kahle, L; Longcope, C; Miller, R; Stanczyk, FZ; Stephenson, HE1
Gingras, S; Groner, B; Moriggl, R; Simard, J1
Andò, S; Donzé, O; Jeannin, E; Maggiolini, M; Picard, D1
Carter, WH; Huynh, PN; Loria, RM1
Griffiths, K; Maynard, PV; Pike, AW; Weston, A1
Adams, JB; Archibald, L; Clarke, C1
Adams, JB; Seymour-Munn, K1
Hinkhouse, M; MacIndoe, JH; Woods, G1
Habrioux, G; Najid, A1
Dauvois, S; Dumont, M; Hatton, AC; Labrie, C; Labrie, F; Mérand, Y; Poirier, D; Poulin, R; Simard, J; Zhao, HF1
Bélanger, A; Labrie, F; Merand, Y; Poirier, D; Poulin, R; Thériault, C1
Adams, JB; Martyn, P1
Poortman, J; Thijssen, JH; van Landeghem, AA1
Labrie, F; Poulin, R1
Dässler, CG; Wilken, H1
Labrie, F; Simard, J1
Ghilchik, MW; James, VH; Lai, LC; Reed, MJ1
Adams, JB1
James, VH; Jones, DL1
Nabuurs, M; Poortman, J; Thijssen, JH; van Landeghem, AA1

Reviews

2 review(s) available for androstenediol and Breast Neoplasms

ArticleYear
Androgen receptor mediated growth control of breast cancer and endometrial cancer modulated by antiandrogen- and androgen-like steroids.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 56, Issue:1-6 Spec N

    Topics: Androgen Antagonists; Androgens; Androstane-3,17-diol; Androstenediol; Antineoplastic Agents, Hormonal; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carcinoma; Carrier Proteins; Endometrial Neoplasms; Estrogen Antagonists; Female; Fibrocystic Breast Disease; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Medroxyprogesterone Acetate; Membrane Transport Proteins; Neoplasm Proteins; Pleural Effusion; Receptors, Androgen; Tumor Cells, Cultured

1996
Control of secretion and the function of C19-delta 5-steroids of the human adrenal gland.
    Molecular and cellular endocrinology, 1985, Volume: 41, Issue:1

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Aldehyde-Lyases; Androgens; Androstenediol; Animals; Anorexia Nervosa; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrogens; Fasting; Female; Glucocorticoids; Humans; Hypophysectomy; Japan; Menopause; Middle Aged; Obesity; Prolactin; Puberty; Steroid 17-alpha-Hydroxylase; Stress, Physiological; Sulfotransferases; Sulfurtransferases; Surgical Procedures, Operative; United States

1985

Trials

1 trial(s) available for androstenediol and Breast Neoplasms

ArticleYear
Phase I study of STX 64 (667 Coumate) in breast cancer patients: the first study of a steroid sulfatase inhibitor.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Mar-01, Volume: 12, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Androstenediol; Breast Neoplasms; Coumarins; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Humans; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Steryl-Sulfatase; Sulfonamides; Sulfonic Acids; Testosterone

2006

Other Studies

34 other study(ies) available for androstenediol and Breast Neoplasms

ArticleYear
Alcohol consumption and serum metabolite concentrations in young women.
    Cancer causes & control : CCC, 2020, Volume: 31, Issue:2

    Topics: Adult; Alcohol Drinking; Androstenediol; Breast Neoplasms; Child; Chromans; Citrates; Cross-Sectional Studies; Diet; Eicosapentaenoic Acid; Female; Follow-Up Studies; Humans; Metabolomics

2020
Sex steroid hormones in pairs of tumor and serum from breast cancer patients and pathobiological role of androstene-3β, 17β-diol.
    Cancer science, 2011, Volume: 102, Issue:10

    Topics: Adult; Androstenediol; Androstenedione; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dehydroepiandrosterone; Estradiol; Estrogen Receptor alpha; Estrone; Female; Gonadal Steroid Hormones; Humans; Middle Aged; Postmenopause; Premenopause

2011
Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells.
    Molecular and cellular endocrinology, 2002, Jul-31, Volume: 193, Issue:1-2

    Topics: Adrenal Glands; Androgens; Androstenediol; Androstenedione; Aromatase; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Estrogen Receptor alpha; Female; Gene Expression Regulation; Humans; Receptors, Estrogen; Transfection; Tumor Cells, Cultured

2002
Hormonal therapy in cancer of the breast. IV. Effect of androstenediol on clinical course and hormonal excretion.
    Cancer, 1952, Volume: 5, Issue:6

    Topics: Androgens; Androstenediol; Breast; Breast Neoplasms; Humans; Neoplasms

1952
The proliferative effects of 5-androstene-3 beta,17 beta-diol and 5 alpha-dihydrotestosterone on cell cycle analysis and cell proliferation in MCF7, T47D and MDAMB231 breast cancer cell lines.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 88, Issue:1

    Topics: Anabolic Agents; Androgens; Androstenediol; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Dihydrotestosterone; Female; Humans; Time Factors

2004
Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 91, Issue:4-5

    Topics: Adaptor Proteins, Signal Transducing; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Androstenediol; Androstenedione; Anilides; Animals; Breast Neoplasms; Carrier Proteins; Cell Division; Chlorocebus aethiops; COS Cells; Cyproterone Acetate; Dihydrotestosterone; Humans; Ligands; Macaca mulatta; Male; Mammary Tumor Virus, Mouse; Mice; Nerve Tissue Proteins; Nitriles; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, AMPA; Receptors, Androgen; Tosyl Compounds; Transcription, Genetic; Tumor Cells, Cultured

2004
Serum concentrations of estrogens, sex hormone-binding globulin, and androgens and risk of breast cancer in postmenopausal women.
    International journal of cancer, 2006, Nov-15, Volume: 119, Issue:10

    Topics: Aged; Androgens; Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Estrogens; Estrone; Female; Humans; Middle Aged; Odds Ratio; Postmenopause; Retrospective Studies; Risk Assessment; Risk Factors; Sex Hormone-Binding Globulin; Testosterone

2006
Adrenal androgen concentrations in breast tumours and in normal breast tissue. The relationship to oestradiol metabolism.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Adenocarcinoma; Adult; Aged; Androstenediol; Androstenediols; Breast; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Radioimmunoassay

1984
Effects of aminoglutethimide on delta 5-androstenediol metabolism in postmenopausal women with breast cancer.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Adenocarcinoma; Adult; Aminoglutethimide; Androstenediol; Androstenediols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Humans; Hydrocortisone; Kinetics; Menopause; Metabolic Clearance Rate; Middle Aged

1982
Dehydroepiandrosterone and androst-5-ene-3 beta,17 beta-diol in human mammary cancer cytosolic and nuclear compartments and their relationship to estrogen receptor.
    Cancer research, 1980, Volume: 40, Issue:10

    Topics: Androstenediol; Androstenediols; Breast Neoplasms; Cell Nucleus; Cross Reactions; Cytosol; Dehydroepiandrosterone; Female; Humans; Radioimmunoassay; Receptors, Estrogen

1980
Estrogenic effects of physiological concentrations of 5-androstene-3 beta, 17 beta-diol and its metabolism in MCF7 human breast cancer cells.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Androstenediol; Androstenediols; Biotransformation; Breast Neoplasms; Cell Line; Cell Nucleus; Cytosol; Dehydroepiandrosterone; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrone; Female; Glycoproteins; Humans; Receptors, Estrogen

1981
Estrogenic effects of 5-androstene-3 beta, 17 beta-diol at physiological concentrations and its possible implication in the etiology of breast cancer.
    Endocrinology, 1983, Volume: 112, Issue:2

    Topics: Androstenediol; Androstenediols; Animals; Breast Neoplasms; Cell Nucleus; Cytosol; DNA; Female; Organ Size; Proteins; Rats; Rats, Inbred Strains; Receptors, Estrogen; Uterus

1983
Metabolism of estradiol-17 beta, 5-androstene-3 beta, 17 beta-diol and testosterone in human breast cancer cells in long-term culture.
    Journal of steroid biochemistry, 1980, Volume: 13, Issue:7

    Topics: Androstenediol; Androstenediols; Breast Neoplasms; Cell Line; Estradiol; Female; Humans; Testosterone

1980
5-En-androstene-3 beta,17 beta-diol inhibits the growth of MCF-7 breast cancer cells when oestrogen receptors are blocked by oestradiol.
    British journal of cancer, 1994, Volume: 70, Issue:6

    Topics: Androstenediol; Breast Neoplasms; Cell Division; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

1994
Estrogen and androgen receptor mediated stimulation and inhibition of proliferation by androst-5-ene-3 beta,17 beta-diol in human mammary cancer cells.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:5

    Topics: Androstane-3,17-diol; Androstenediol; Binding, Competitive; Breast Neoplasms; Cell Division; Female; Humans; Metribolone; Receptors, Androgen; Receptors, Estrogen; Tumor Cells, Cultured

1993
Relationship of serum dehydroepiandrosterone (DHEA), DHEA sulfate, and 5-androstene-3 beta, 17 beta-diol to risk of breast cancer in postmenopausal women.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:3

    Topics: Aged; Anabolic Agents; Androstenediol; Bias; Blood Donors; Breast Neoplasms; Case-Control Studies; Confidence Intervals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Follow-Up Studies; Humans; Linear Models; Middle Aged; Missouri; Odds Ratio; Postmenopause; Prospective Studies; Risk Factors

1997
Induction of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene transcription in human breast cancer cell lines and in normal mammary epithelial cells by interleukin-4 and interleukin-13.
    Molecular endocrinology (Baltimore, Md.), 1999, Volume: 13, Issue:1

    Topics: Androstenediol; Base Sequence; Binding Sites; Breast; Breast Neoplasms; Conserved Sequence; Enzyme Inhibitors; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-13; Interleukin-4; Multienzyme Complexes; Progesterone Reductase; Promoter Regions, Genetic; Receptors, Estrogen; STAT6 Transcription Factor; Staurosporine; Steroid Isomerases; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation

1999
Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha.
    Cancer research, 1999, Oct-01, Volume: 59, Issue:19

    Topics: Androgens; Androstenediol; Breast Neoplasms; Cell Division; Cloning, Molecular; Dehydroepiandrosterone; Dihydrotestosterone; Estrogen Receptor alpha; Female; Genes, Reporter; HeLa Cells; Humans; Luciferases; Receptors, Estrogen; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Testosterone; Transfection; Tumor Cells, Cultured; Uterus

1999
17 alpha androstenediol inhibition of breast tumor cell proliferation in estrogen receptor-positive and -negative cell lines.
    Cancer detection and prevention, 2000, Volume: 24, Issue:5

    Topics: Anabolic Agents; Androgen Antagonists; Androgen Receptor Antagonists; Androstenediol; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Receptor alpha; Flutamide; Humans; Models, Biological; Receptors, Androgen; Receptors, Estrogen; Stereoisomerism; Tumor Cells, Cultured

2000
Analysis of dehydroepiandrosterone and androstenediol in human breast tissue using high resolution gas chromatography--mass spectrometry.
    European journal of cancer, 1977, Volume: 13, Issue:9

    Topics: Adenofibroma; Androstenediol; Androstenediols; Breast; Breast Neoplasms; Chromatography, Gas; Dehydroepiandrosterone; Female; Humans; Mass Spectrometry

1977
Adrenal dehydroepiandrosterone and human mammary cancer.
    Cancer research, 1978, Volume: 38, Issue:11 Pt 2

    Topics: Adrenal Glands; Androstenediol; Animals; Binding, Competitive; Breast Neoplasms; Cell Nucleus; Cytosol; Dehydroepiandrosterone; Estrone; Humans; In Vitro Techniques; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Sulfurtransferases

1978
Estrogen receptor and C19-5-ene-steroid concentrations in the nuclear fraction from human breast carcinoma tissue.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 43, Issue:6

    Topics: Androstenediol; Androstenols; Breast Neoplasms; Carcinoma; Cell Nucleus; Dehydroepiandrosterone; Female; Humans; Menopause; Receptors, Estrogen

1992
Dehydroepiandrosterone and estrone 17-ketosteroid reductases in MCF-7 human breast cancer cells.
    Breast cancer research and treatment, 1990, Volume: 16, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Androstenediol; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Dehydroepiandrosterone; Estrogens; Female; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Subcellular Fractions; Substrate Specificity; Tumor Cells, Cultured

1990
Biological effects of adrenal androgens on MCF-7 and BT-20 human breast cancer cells.
    Oncology, 1990, Volume: 47, Issue:3

    Topics: Androstenediol; Androstenediols; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Receptors, Estrogen; Tumor Cells, Cultured

1990
Interactions between estrogens, androgens, progestins, and glucocorticoids in ZR-75-1 human breast cancer cells.
    Annals of the New York Academy of Sciences, 1990, Volume: 595

    Topics: Androgens; Androstenediol; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Estrogens; Gene Expression; Glucocorticoids; Glycoproteins; Humans; In Vitro Techniques; Insulin; Medroxyprogesterone; Medroxyprogesterone Acetate; Membrane Transport Proteins; Neoplasm Proteins; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tumor Cells, Cultured

1990
Extensive esterification of adrenal C19-delta 5-sex steroids to long-chain fatty acids in the ZR-75-1 human breast cancer cell line.
    The Journal of biological chemistry, 1989, Jun-05, Volume: 264, Issue:16

    Topics: Acetylation; Adrenal Cortex; Androstenediol; Androstenediols; Breast Neoplasms; Cell Line; Dehydroepiandrosterone; Esterification; Fatty Acids; Humans; Intracellular Fluid; Kinetics; Protein Precursors; Tritium

1989
Long-chain fatty acid esters of 5-androstene-3 beta, 17 beta-diol: composition and turnover in human mammary cancer cells in culture.
    Steroids, 1989, Volume: 54, Issue:2

    Topics: Acylation; Androstenediol; Androstenediols; Breast Neoplasms; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Estradiol; Fatty Acids; Female; Humans; Stearic Acids; Tumor Cells, Cultured

1989
Uptake and concentration of steroid hormones in mammary tissues.
    Annals of the New York Academy of Sciences, 1986, Volume: 464

    Topics: Adult; Androgens; Androstenediol; Biopsy; Breast; Breast Diseases; Breast Neoplasms; Cell Nucleus; Cytosol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Epidemiologic Methods; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged

1986
Stimulation of cell proliferation and estrogenic response by adrenal C19-delta 5-steroids in the ZR-75-1 human breast cancer cell line.
    Cancer research, 1986, Volume: 46, Issue:10

    Topics: Androstenediol; Androstenediols; Breast Neoplasms; Cell Division; Cell Line; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Receptors, Progesterone

1986
[Dehydroepiandrosterone and other endocrine parameters in breast cancer].
    Zentralblatt fur Gynakologie, 1987, Volume: 109, Issue:1

    Topics: Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Humans; Sex Hormone-Binding Globulin

1987
Adrenal C19-5-ene steroids induce full estrogenic responses in rat pituitary gonadotrophs.
    Journal of steroid biochemistry, 1987, Volume: 26, Issue:5

    Topics: Androstenediol; Androstenediols; Animals; Breast Neoplasms; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Piperidines; Pituitary Gland, Anterior; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen

1987
The effects of androgens and cortisol on the in vivo metabolism of oestradiol.
    Journal of steroid biochemistry, 1988, Volume: 30, Issue:1-6

    Topics: Aged; Androgens; Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Humans; Hydrocortisone; Metabolic Clearance Rate

1988
The identification, quantification and possible origin of non-polar conjugates in human plasma.
    Journal of steroid biochemistry, 1985, Volume: 22, Issue:2

    Topics: Acne Vulgaris; Adult; Aged; Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Female; Hirsutism; Humans; Male; Middle Aged; Pregnancy; Pregnenolone; Steroids

1985
Endogenous concentration and subcellular distribution of androgens in normal and malignant human breast tissue.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Androgens; Androstenediol; Breast; Breast Neoplasms; Cell Nucleus; Cytosol; Dehydroepiandrosterone; Estradiol; Female; Humans; Menopause; Middle Aged

1985