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androstane-3,17-diol and Cancer of Prostate

androstane-3,17-diol has been researched along with Cancer of Prostate in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199020 (33.90)18.7374
1990's8 (13.56)18.2507
2000's16 (27.12)29.6817
2010's14 (23.73)24.3611
2020's1 (1.69)2.80

Authors

AuthorsStudies
Boutin, S; Maltais, R; Poirier, D; Roy, J1
Cookson, MS; Dhanasekaran, DN; Disch, BC; Fung, KM; Ihnat, MA; Jayaraman, M; Lai, DV; Lin, HK; Stratton, KL; Thorpe, JE; Webb, ZD; Wu, W; Xia, D; Yang, Q; Yu, Z; Zhao, L1
Azen, CG; Pike, MC; Stanczyk, FZ1
Hara, N; Ishizaki, F; Kawasaki, T; Miyashiro, Y; Naito, M; Nishiyama, T; Takahashi, K; Takizawa, I1
Colciago, A; Eberini, I; Festuccia, C; Magni, P; Montagnani-Marelli, M; Mornati, O; Motta, M; Negri-Cesi, P; Piccolella, M; Ruscica, M1
Figg, WD; Gong, Z; Goodman, PJ; Hoque, AM; Hsing, AW; Neuhouser, ML; Reichardt, JK; Schenk, JM; Stanczyk, FZ; Tangen, CM; Thompson, IM; Till, C1
Ando, T; Hara, N; Ishizaki, F; Miyashiro, Y; Nishiyama, T; Takeda, K; Takizawa, I; Tomita, Y1
Akre, O; Ekström, L; Gustafsson, O; Kjellman, A; Olsson, M; Rane, A; Schulze, J1
Biserni, A; Caruso, D; Ciana, P; Della Torre, S; Dondi, D; Locatelli, A; Maggi, A; Piccolella, M; Poletti, A; Ramachandran, B; Rusmini, P; Sau, D1
English, DR; Gardner-Stephen, D; Giles, GG; Gregory, PA; Hopper, JL; Hu, DG; Mackenzie, PI; Severi, G; Tilley, WD; Treloar, J1
Bai, S; Kennerley, BJ; Lih, FB; Mohler, JL; Titus, MA; Tomer, KB; Wilson, EM1
Aiello, A; Bacchetti, S; Bassi, P; Benvenuti, V; Ciccone, S; Colussi, C; Farsetti, A; Gallucci, M; Grasselli, A; Lo Bello, M; Mazzetti, AP; Nanni, S; Pantisano, V; Pierconti, F; Pinto, F; Pontecorvi, A; Re, A; Sentinelli, S; Strigari, L; Trimarchi, F1
Andersson, S; Bergerheim, U; Butler, R; Gustafsson, JÅ; Kim, HJ; Muthusamy, S; Waage, L1
Chu, LW; Figg, WD; Goodman, PJ; Hoque, A; Hsing, AW; Kristal, AR; Lippman, SM; Neuhouser, ML; Patel, SK; Platz, EA; Reichardt, JK; Stanczyk, FZ; Tangen, CM; Thompson, IM; Till, C; Van Bokhoven, A1
Hara, N; Ishizaki, F; Kawasaki, T; Nishiyama, T; Saito, T; Takahashi, K1
Bauman, DR; Lin, HK; Peehl, DM; Penning, TM; Rizner, TL; Steckelbroeck, S1
Centola, M; Cowan, R; Dozmorov, I; Lin, HK; Nunlist, EH; Tang, Y1
Chen, AC; Conway, F; Desai, M; MacChia, RJ; Magai, C; Neugut, AI1
Centola, M; Cowan, R; Culkin, DJ; Dozmorov, I; Frank, MB; Li, X; Lin, HK; Nunlist, EH; Tang, Y; Zimmerman, RA1
Gustafsson, JA; Imamov, O; Lopatkin, NA1
Ciana, P; Guerini, V; Katzenellenbogen, BS; Maggi, A; Martini, L; Martini, PG; Motta, M; Poletti, A; Rusmini, P; Sau, D; Scaccianoce, E1
Cheng, I; Henderson, BE; Koh, WP; Kolonel, LN; Pike, MC; Stram, DO; Yu, MC1
Bergh, A; Hallmans, G; Kaaks, R; Rinaldi, S; Stattin, P; Stenman, UH; Stocks, T; Wirén, S1
Fung, KM; Lin, HK; Titus, MA; Yang, Q1
Ghanadian, R; Puah, CM2
Ghanadian, R; Puah, CM; Williams, G1
Alroy, J; Merk, FB; Orgad, U; Ucci, A1
Hammond, GL; Leinonen, P; Vihko, R1
Bélanger, A; Guillemette, C1
Bélanger, A; Guillemette, C; Hum, DW1
Hsing, AW1
Gann, PH; Hennekens, CH; Longcope, C; Ma, J; Stampfer, MJ1
Harvei, S; Jellum, E; Lobo, RA; Ross, RK; Stanczyk, FZ; Ursin, G; Vatten, LJ1
Chang, C; Lardy, H; Messing, E; Miyamoto, H; Yeh, S1
Allen, NE; Appleby, PN; Davey, GK; Key, TJ1
Ball, MJ; Habito, RC; Leslie, E; Montalto, J1
Feldman, HA; Kalish, LA; Longcope, C; McKinlay, JB; Mohr, BA1
Adams, JY; Alroy, J; Leav, I; Merk, FB; Schelling, KH2
Gallagher, RP; John, EM; Kolonel, LN; Stanczyk, FZ; West, DW; Whittemore, AS; Wu, AH1
Bonafe, M; Dallapiccola, B; De Luca, A; Franceschi, C; Froio, F; Margiotti, K; Micali, F; Novelli, G; Pearce, CL; Reichardt, JK; Ricci-Barbini, V; Sangiuolo, F1
Brown, JR; Farnsworth, WE1
Jacobi, GH; Wilson, JD1
Attramadal, A; Djoseland, O; Hansson, V; Naess, O; Weddington, SC1
Bruchovsky, N; Lieskovsky, G1
Charles, JF; Floch, HH; Morfin, RF1
Bartsch, W; Janssen, W; Krieg, M; Voigt, KD1
Altwein, JE; Jacobi, GH; Kurth, KH1
Cavazos, LF; Charles, JF; Floch, HH; Leav, I; Morfin, RF; Ofner, P1
Albert, J; Geller, J; Geller, S; Lopez, D1
Altwein, JE; Bandhauer, K; Knapstein, P; Orestano, F1
Bélanger, A; Brochu, M; Caron, S; Couture, J; Cusan, L; Dupont, A; Labrie, F; Lacoste, D; Noël, C1
de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R1
Bongini, M; Bozzolan, F; Doukani, A; Mauvais-Jarvis, P; Poizat, R; Wright, F1
Bélanger, A; Brochu, M; Cliche, J1
Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F2
Becker, H; Kurniawan, E; Tamm, J; Volkwein, U1

Reviews

1 review(s) available for androstane-3,17-diol and Cancer of Prostate

ArticleYear
Histochemical studies of epithelial cell glycoconjugates in atrophic, metaplastic, hyperplastic, and neoplastic canine prostate.
    Laboratory investigation; a journal of technical methods and pathology, 1984, Volume: 50, Issue:3

    Topics: Androstane-3,17-diol; Animals; Binding, Competitive; Carbohydrates; Castration; Cell Differentiation; Dihydrotestosterone; Dog Diseases; Dogs; Epithelium; Estradiol; Histocytochemistry; Male; Prostate; Prostatic Diseases; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Mitogen

1984

Trials

3 trial(s) available for androstane-3,17-diol and Cancer of Prostate

ArticleYear
Effect of finasteride on serum levels of androstenedione, testosterone and their 5α-reduced metabolites in men at risk for prostate cancer.
    The Journal of steroid biochemistry and molecular biology, 2013, Volume: 138

    Topics: 5-alpha Reductase Inhibitors; Aged; Androstane-3,17-diol; Androstenedione; Dihydrotestosterone; Finasteride; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone

2013
Associations of serum sex steroid hormone and 5α-androstane-3α,17β-diol glucuronide concentrations with prostate cancer risk among men treated with finasteride.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012, Volume: 21, Issue:10

    Topics: 5-alpha Reductase Inhibitors; Aged; Androstane-3,17-diol; Case-Control Studies; Finasteride; Glucuronides; Gonadal Steroid Hormones; Humans; Male; Middle Aged; Prostatic Neoplasms; Risk; Sex Hormone-Binding Globulin

2012
Effects of replacing meat with soyabean in the diet on sex hormone concentrations in healthy adult males.
    The British journal of nutrition, 2000, Volume: 84, Issue:4

    Topics: Adult; Androstane-3,17-diol; Cross-Over Studies; Dietary Proteins; Dihydrotestosterone; Estradiol; Glycine max; Gonadal Steroid Hormones; Humans; Male; Meat; Middle Aged; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Testosterone

2000

Other Studies

55 other study(ies) available for androstane-3,17-diol and Cancer of Prostate

ArticleYear
Formation of 5α-dihydrotestosterone from 5α-androstane-3α,17β-diol in prostate cancer LAPC-4 cells - Identifying inhibitors of non-classical pathways producing the most potent androgen.
    Bioorganic & medicinal chemistry letters, 2020, 01-15, Volume: 30, Issue:2

    Topics: Androgens; Androstane-3,17-diol; Cell Line, Tumor; Dihydrotestosterone; Humans; Male; Prostatic Neoplasms; Receptors, Androgen; Structure-Activity Relationship

2020
Transition from androgenic to neurosteroidal action of 5α-androstane-3α, 17β-diol through the type A γ-aminobutyric acid receptor in prostate cancer progression.
    The Journal of steroid biochemistry and molecular biology, 2018, Volume: 178

    Topics: Aldo-Keto Reductase Family 1 Member C3; Anabolic Agents; Androstane-3,17-diol; Cell Proliferation; Disease Progression; ErbB Receptors; Humans; Male; Prostatic Neoplasms; Receptors, GABA-A; Signal Transduction; Tumor Cells, Cultured

2018
Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer.
    Scientific reports, 2013, Volume: 3

    Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Androgens; Androstane-3,17-diol; Cell Line, Tumor; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Male; Middle Aged; Prostatic Neoplasms; RNA Interference; RNA, Small Interfering

2013
In vitro chronic administration of ERbeta selective ligands and prostate cancer cell growth: hypotheses on the selective role of 3beta-adiol in AR-positive RV1 cells.
    BioMed research international, 2014, Volume: 2014

    Topics: Androstane-3,17-diol; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Estrogen Receptor beta; HEK293 Cells; Humans; Male; Prostatic Neoplasms; Receptors, Androgen

2014
Serum androgens and prostate cancer risk: results from the placebo arm of the Prostate Cancer Prevention Trial.
    Cancer causes & control : CCC, 2016, Volume: 27, Issue:2

    Topics: Aged; Androgens; Androstane-3,17-diol; Arm; Biopsy; Case-Control Studies; Estradiol; Estrone; Humans; Kallikreins; Linear Models; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Sex Hormone-Binding Globulin; Testosterone

2016
Dihydrotestosterone synthesis pathways from inactive androgen 5α-androstane-3β,17β-diol in prostate cancer cells: Inhibition of intratumoural 3β-hydroxysteroid dehydrogenase activities by abiraterone.
    Scientific reports, 2016, 08-26, Volume: 6

    Topics: 3-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstenes; Cell Line, Tumor; Dihydrotestosterone; Enzyme Inhibitors; Humans; Male; Neoplasm Proteins; Prostatic Neoplasms

2016
Radical prostatectomy: influence on serum and urinary androgen levels.
    The Prostate, 2010, Feb-01, Volume: 70, Issue:2

    Topics: Aged; Androgens; Androstane-3,17-diol; Androsterone; Cross-Sectional Studies; Dihydrotestosterone; Follicle Stimulating Hormone; Glucuronides; Humans; Inhibins; Luteinizing Hormone; Male; Middle Aged; Prostate; Prostatectomy; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Testosterone

2010
Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol.
    Endocrine-related cancer, 2010, Volume: 17, Issue:3

    Topics: Anabolic Agents; Androstane-3,17-diol; Animals; Apoptosis; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Drug Combinations; Estrogen Receptor beta; Humans; Laminin; Male; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Prostatic Neoplasms; Proteoglycans; Receptors, Androgen; Survival Rate; Xenograft Model Antitumor Assays

2010
A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide.
    Molecular pharmacology, 2010, Volume: 78, Issue:4

    Topics: Androstane-3,17-diol; Binding Sites; Cell Line, Tumor; Glucuronosyltransferase; Hepatocyte Nuclear Factor 3-alpha; Humans; Male; Minor Histocompatibility Antigens; Polymorphism, Genetic; Promoter Regions, Genetic; Prostatic Neoplasms

2010
Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer.
    Cancer research, 2011, Feb-15, Volume: 71, Issue:4

    Topics: Androgens; Androstane-3,17-diol; Animals; Carcinoma; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Male; Mice; Mice, Nude; Prostatic Neoplasms; Receptors, Androgen; Transcriptional Activation; Transplantation, Heterologous; Tumor Cells, Cultured

2011
Silencing of GSTP1, a prostate cancer prognostic gene, by the estrogen receptor-β and endothelial nitric oxide synthase complex.
    Molecular endocrinology (Baltimore, Md.), 2011, Volume: 25, Issue:12

    Topics: Androstane-3,17-diol; Cell Line, Tumor; Cell Movement; Chromatin Assembly and Disassembly; DNA Methylation; Estradiol; Estrogen Receptor beta; Gene Silencing; Glutathione S-Transferase pi; Humans; Male; Nitric Oxide Synthase Type III; Prognosis; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Transport; Tissue Array Analysis; Transcription, Genetic

2011
Estrogen receptor β and 17β-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Dec-13, Volume: 108, Issue:50

    Topics: Androstane-3,17-diol; Cell Proliferation; Dihydrotestosterone; Epithelium; Estrogen Receptor beta; HEK293 Cells; Humans; Hyperplasia; Immunohistochemistry; Male; Models, Biological; Prostate; Prostatic Neoplasms; Racemases and Epimerases; Signal Transduction; Transcriptional Activation

2011
Decrease in lean body mass in men with prostate cancer receiving androgen deprivation therapy: mechanism and biomarkers.
    Urology, 2013, Volume: 81, Issue:2

    Topics: Aged; Androgen Antagonists; Androstane-3,17-diol; Biomarkers; Body Composition; Body Mass Index; Calcitriol; Dihydrotestosterone; Electric Impedance; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Statistics, Nonparametric; Testosterone; Thinness

2013
Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.
    Endocrinology, 2003, Volume: 144, Issue:7

    Topics: 17-Hydroxysteroid Dehydrogenases; Adenocarcinoma; Androstane-3,17-diol; Animals; Bone Neoplasms; COS Cells; Dihydrotestosterone; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isoenzymes; Male; Prostate; Prostatic Neoplasms; Testosterone; Tumor Cells, Cultured

2003
Partitioning of 5alpha-dihydrotestosterone and 5alpha-androstane-3alpha, 17beta-diol activated pathways for stimulating human prostate cancer LNCaP cell proliferation.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 91, Issue:3

    Topics: Androstane-3,17-diol; Cell Division; Cell Line, Tumor; Dihydrotestosterone; Gene Expression Profiling; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Receptors, Androgen

2004
Prostate-specific antigen, sex steroid hormones, and the insulin-like growth factor axis in U.S.-born, Jamaican, and Haitian black men: a pilot study.
    Urology, 2004, Volume: 64, Issue:3

    Topics: Adult; Aged; Androstane-3,17-diol; Black or African American; Emigration and Immigration; Ethnicity; Feasibility Studies; Genetic Predisposition to Disease; Gonadal Steroid Hormones; Haiti; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Jamaica; Male; Middle Aged; New York City; Patient Selection; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Sex Hormone-Binding Globulin; Testosterone; United States

2004
5alpha-Androstane-3alpha,17beta-diol activates pathway that resembles the epidermal growth factor responsive pathways in stimulating human prostate cancer LNCaP cell proliferation.
    Prostate cancer and prostatic diseases, 2004, Volume: 7, Issue:4

    Topics: Anabolic Agents; Androstane-3,17-diol; Cell Proliferation; Computational Biology; Epidermal Growth Factor; Gene Expression Profiling; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tumor Cells, Cultured

2004
Estrogen receptor beta in prostate cancer.
    The New England journal of medicine, 2004, Dec-23, Volume: 351, Issue:26

    Topics: 5-alpha Reductase Inhibitors; Androstane-3,17-diol; Animals; Antineoplastic Agents, Hormonal; Estrogen Receptor beta; Finasteride; Humans; Ligands; Male; Mice; Prostatic Neoplasms

2004
The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits prostate cancer cell migration through activation of the estrogen receptor beta subtype.
    Cancer research, 2005, Jun-15, Volume: 65, Issue:12

    Topics: Anabolic Agents; Androstane-3,17-diol; Cadherins; Cell Line, Tumor; Cell Migration Inhibition; Cell Movement; Dihydrotestosterone; Estrogen Receptor beta; Humans; Male; Prostatic Neoplasms; Receptors, Androgen; Transfection

2005
Comparison of prostate-specific antigen and hormone levels among men in Singapore and the United States.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:7

    Topics: Age Distribution; Aged; Androstane-3,17-diol; Ethnicity; Humans; Incidence; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Singapore; Testosterone; United States

2005
Androgens and prostate cancer risk: a prospective study.
    The Prostate, 2007, Aug-01, Volume: 67, Issue:11

    Topics: Androgens; Androstane-3,17-diol; Humans; Male; Middle Aged; Prospective Studies; Prostatic Neoplasms; Risk Factors; Sex Hormone-Binding Globulin; Testosterone

2007
5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression.
    Journal of cellular biochemistry, 2008, Aug-01, Volume: 104, Issue:5

    Topics: Androstane-3,17-diol; Apoptosis; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytoplasm; Dihydrotestosterone; Disease Progression; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Male; Models, Biological; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Receptors, Androgen; RNA, Small Interfering; Signal Transduction; Time Factors

2008
Relationships between oestradiol-17 beta, testosterone, dihydrotestosterone and 5 alpha-androstane-3 alpha, 27 beta-diol in human benign hypertrophy and carcinoma of the prostate.
    The Journal of endocrinology, 1981, Volume: 88, Issue:2

    Topics: Adult; Aged; Androgens; Androstane-3,17-diol; Dihydrotestosterone; Estradiol; Humans; Male; Middle Aged; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone

1981
Urinary unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol in patients with prostatic tumours.
    Urological research, 1982, Volume: 10, Issue:2

    Topics: Adult; Aged; Androstane-3,17-diol; Androstanols; Chromatography, Thin Layer; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Radioimmunoassay; Specimen Handling; Stereoisomerism

1982
Circulating unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol in elderly men and patients with prostatic tumours.
    Age and ageing, 1983, Volume: 12, Issue:3

    Topics: Aged; Androstane-3,17-diol; Androstanols; Dihydrotestosterone; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms

1983
Testosterone and some of its precursors and metabolites in the human epididymis.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:3

    Topics: Aged; Androstane-3,17-diol; Androstenedione; Androsterone; Dihydrotestosterone; Epididymis; Estrogens; Humans; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis; Testosterone; Vas Deferens

1980
Glucuronosyltransferase activity in human cancer cell line LNCaP.
    Molecular and cellular endocrinology, 1995, Volume: 107, Issue:2

    Topics: Androstane-3,17-diol; Androsterone; Cell Line; Dihydrotestosterone; Glucuronates; Glucuronosyltransferase; Humans; Male; Prostatic Neoplasms; Testosterone; Tumor Cells, Cultured; Uridine Diphosphate Glucuronic Acid

1995
Specificity of glucuronosyltransferase activity in the human cancer cell line LNCaP, evidence for the presence of at least two glucuronosyltransferase enzymes.
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4

    Topics: Adenocarcinoma; Androstane-3,17-diol; Androsterone; Binding, Competitive; Dihydrotestosterone; Estradiol; Estriol; Estrone; Glucuronosyltransferase; Humans; Kinetics; Male; Prostatic Neoplasms; Substrate Specificity; Testosterone; Tumor Cells, Cultured

1995
Hormones and prostate cancer: where do we go from here?
    Journal of the National Cancer Institute, 1996, Aug-21, Volume: 88, Issue:16

    Topics: Androstane-3,17-diol; Case-Control Studies; Cholestenone 5 alpha-Reductase; Gonadal Steroid Hormones; Humans; Male; Oxidoreductases; Prostatic Neoplasms; Reproducibility of Results; Testosterone

1996
Prospective study of sex hormone levels and risk of prostate cancer.
    Journal of the National Cancer Institute, 1996, Aug-21, Volume: 88, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Androstane-3,17-diol; Case-Control Studies; Dihydrotestosterone; Estradiol; Gonadal Steroid Hormones; Humans; Male; Middle Aged; Odds Ratio; Prolactin; Prospective Studies; Prostatic Neoplasms; Risk; Sex Hormone-Binding Globulin; Testosterone

1996
Androgens in serum and the risk of prostate cancer: a nested case-control study from the Janus serum bank in Norway.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:11

    Topics: Adult; Aged; Androgens; Androstane-3,17-diol; Biomarkers; Blood Specimen Collection; Case-Control Studies; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Humans; Male; Middle Aged; Norway; Oxidoreductases; Prostatic Neoplasms; Risk Factors; Time Factors

1997
Delta5-androstenediol is a natural hormone with androgenic activity in human prostate cancer cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Sep-15, Volume: 95, Issue:19

    Topics: Androgens; Androstane-3,17-diol; Androstenediol; Anilides; Flutamide; Humans; Male; Mutation; Nitriles; Nuclear Receptor Coactivators; Oncogene Proteins; Prostatic Neoplasms; Protein Conformation; Receptors, Androgen; Steroids; Testosterone; Tosyl Compounds; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured

1998
Hormones and diet: low insulin-like growth factor-I but normal bioavailable androgens in vegan men.
    British journal of cancer, 2000, Volume: 83, Issue:1

    Topics: Adult; Androgens; Androstane-3,17-diol; Anthropometry; Biomarkers; Cross-Sectional Studies; Diet; Diet, Vegetarian; England; Humans; Insulin-Like Growth Factor I; Luteinizing Hormone; Male; Meat; Prostatic Neoplasms; Risk Factors; Sex Hormone-Binding Globulin; Testosterone

2000
Are serum hormones associated with the risk of prostate cancer? Prospective results from the Massachusetts Male Aging Study.
    Urology, 2001, Volume: 57, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Aged; Androgens; Androstane-3,17-diol; Estrogens; Follow-Up Studies; Humans; Male; Massachusetts; Middle Aged; Pituitary Hormones; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Risk Factors; Sampling Studies

2001
Role of canine basal cells in prostatic post natal development, induction of hyperplasia, sex hormone-stimulated growth; and the ductal origin of carcinoma.
    The Prostate, 2001, May-15, Volume: 47, Issue:3

    Topics: Adenocarcinoma; Androstane-3,17-diol; Animals; Cell Division; Dihydrotestosterone; Disease Models, Animal; Dog Diseases; Dogs; Estradiol; Gonadal Steroid Hormones; Immunohistochemistry; Keratins; Ki-67 Antigen; Male; Orchiectomy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen

2001
Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:5

    Topics: Age Distribution; Aged; Aged, 80 and over; Aging; Analysis of Variance; Androstane-3,17-diol; Androsterone; Asian People; Biomarkers; Black People; British Columbia; California; Case-Control Studies; Cholestenone 5 alpha-Reductase; Hawaii; Humans; Life Style; Male; Middle Aged; Oxidoreductases; Population Surveillance; Prostatic Neoplasms; Reference Values; Risk Assessment; Risk Factors; Sensitivity and Specificity; White People

2001
Evidence for an association between the SRD5A2 (type II steroid 5 alpha-reductase) locus and prostate cancer in Italian patients.
    Disease markers, 2000, Volume: 16, Issue:3-4

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenocarcinoma; Aged; Aged, 80 and over; Amino Acid Substitution; Androstane-3,17-diol; Codon; Dinucleotide Repeats; Ethnicity; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genotype; Humans; Italy; Male; Middle Aged; Mutation, Missense; Neoplasm Proteins; Polymorphism, Genetic; Prostatic Neoplasms; Risk

2000
Role of canine basal cells in postnatal prostatic development, induction of hyperplasia, and sex hormone-stimulated growth; and the ductal origin of carcinoma.
    The Prostate, 2001, Aug-01, Volume: 48, Issue:3

    Topics: Adenocarcinoma; Androstane-3,17-diol; Animals; Cell Division; Dihydrotestosterone; Disease Models, Animal; Dog Diseases; Dogs; Estradiol; Gonadal Steroid Hormones; Immunohistochemistry; Keratins; Ki-67 Antigen; Male; Orchiectomy; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen

2001
Androgen of the human prostate.
    Endocrine research communications, 1976, Volume: 3, Issue:2

    Topics: Androgens; Androstane-3,17-diol; Desoxycorticosterone; Dihydrotestosterone; Female; Humans; Male; Organ Specificity; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Sex Factors; Testosterone

1976
Formation of 5alpha-androstane-3alpha,17beta-diol by normal and hypertrophic human prostate.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:1

    Topics: Adult; Age Factors; Aged; Androstane-3,17-diol; Androstanes; Cytosol; Dihydrotestosterone; Female; Humans; Male; Microsomes; Middle Aged; NAD; NADP; Organ Size; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Time Factors

1977
Androgen receptors in male sex tissues of rats and humans.
    Progress in clinical and biological research, 1976, Volume: 6

    Topics: Androstane-3,17-diol; Androstenedione; Animals; Dihydrotestosterone; Epididymis; Humans; Male; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Steroid; Testis; Testosterone

1976
Increased ratio of 5 alpha-reductase: 3 alpha (beta)-hydroxysteroid dehydrogenase activities in the hyperplastic human prostate.
    The Journal of endocrinology, 1979, Volume: 80, Issue:3

    Topics: 3-Hydroxysteroid Dehydrogenases; Aged; Androstane-3,17-diol; Chromatography, Thin Layer; Dihydrotestosterone; Humans; Male; Middle Aged; Oxidoreductases; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone; Time Factors

1979
C19O2-Steroid transformations in the human normal, hyperplastic and cancerous prostate.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:1B

    Topics: Androstane-3,17-diol; Androstanols; Dihydrotestosterone; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxidoreductases; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone

1979
A comparative study of binding, metabolism and endogenous levels of androgens in normal, hyperplastic and carcinomatous human prostate.
    Journal of steroid biochemistry, 1979, Volume: 11, Issue:1B

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Androstane-3,17-diol; Dihydrotestosterone; Humans; Male; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Receptors, Steroid; Sex Hormone-Binding Globulin; Testosterone

1979
[Bromocriptine and prostatic carcinoma: testosterone metabolism in relation to tumor grading (author's transl)].
    Der Urologe. Ausg. A, 1979, Volume: 18, Issue:2

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Androgens; Androstane-3,17-diol; Bromocriptine; Dihydrotestosterone; Humans; Male; Prostatic Neoplasms; Testosterone

1979
Correlative study of the morphology and C19-steroid metabolism of benign and cancerous human prostatic tissue.
    Cancer, 1977, Volume: 39, Issue:4

    Topics: Androgens; Androstane-3,17-diol; Androstenedione; Carcinoma, Transitional Cell; Dihydrotestosterone; Humans; Hyperplasia; In Vitro Techniques; Male; Prostate; Prostatic Neoplasms; Testosterone

1977
A method for tissue extraction and determination of prostate concentrations of endogenous androgens by radioimmunoassay.
    Journal of immunological methods, 1976, Volume: 12, Issue:3-4

    Topics: Androgens; Androstane-3,17-diol; Androstenedione; Dihydrotestosterone; Humans; Kidney; Male; Methods; Prostate; Prostatic Neoplasms; Radioimmunoassay; Spleen; Testosterone

1976
Mode of action of progesterone, gestonorone capronate (Depostat) and cyproterone acetate (Androcur) on the metabolism of testosterone in human prostatic adenoma: in vitro and in vivo investigations.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:6

    Topics: Adenoma; Androstane-3,17-diol; Cyproterone; Dihydrotestosterone; Gestonorone Caproate; Humans; Male; Muscles; Progesterone; Prostate; Prostatic Neoplasms; Testosterone

1975
Steroid glucuronides: human circulatory levels and formation by LNCaP cells.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 40, Issue:4-6

    Topics: Adolescent; Adult; Aging; Androstane-3,17-diol; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Glucuronates; Humans; Male; Prostatic Neoplasms; Sex Hormone-Binding Globulin; Sulfates; Tumor Cells, Cultured

1991
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured

1991
Decreased urinary 5 alpha-androstane-3 alpha,17 beta-diol glucuronide excretion in patients with benign prostatic hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:2

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aging; Androstane-3,17-diol; Androstanols; Androstenedione; Dihydrotestosterone; Humans; Male; Middle Aged; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone

1985
Levels of plasma steroid glucuronides in intact and castrated men with prostatic cancer.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 62, Issue:5

    Topics: Aged; Androgens; Androstane-3,17-diol; Androstenediol; Androsterone; Dehydroepiandrosterone; Dihydrotestosterone; Glucuronates; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Testosterone

1986
Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate.
    Journal of steroid biochemistry, 1987, Volume: 28, Issue:6

    Topics: Aged; Aminoglutethimide; Androstane-3,17-diol; Androstanols; Androsterone; Anilides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flutamide; Glucuronates; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms

1987
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1988, Volume: 11, Issue:5

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Anilides; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dehydroepiandrosterone; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Kinetics; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Prolactin; Prostatic Neoplasms; Testosterone; Triptorelin Pamoate

1988
Concentrations of unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol and 5 alpha-androstane-3 beta, 17 beta-diol and their precursor in human testicular tissue. Comparison with testosterone, 5 alpha-dihydrotestosterone, estradiol-17 beta, and with ster
    Journal of steroid biochemistry, 1987, Volume: 26, Issue:3

    Topics: Aged; Aged, 80 and over; Androstane-3,17-diol; Androstanols; Dihydrotestosterone; Epididymis; Estradiol; Humans; Male; Prostatic Neoplasms; Testis; Testosterone

1987