anastrozole has been researched along with Stunted Growth in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Letrozole was more potent in hormonal manipulation than anastrozole." | 2.79 | Letrozole vs anastrozole for height augmentation in short pubertal males: first year data. ( Kumar, RB; Neely, EK; Payne, SL; Ranadive, SA; Suchet, DI, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Tarçın, G | 1 |
| Koç, C | 1 |
| Turan, H | 1 |
| Ercan, O | 1 |
| Shams, K | 1 |
| Cameo, T | 1 |
| Fennoy, I | 1 |
| Hassoun, AA | 1 |
| Lerner, SE | 1 |
| Aranoff, GS | 1 |
| Sopher, AB | 1 |
| Yang, C | 1 |
| McMahon, DJ | 1 |
| Oberfield, SE | 1 |
| Neely, EK | 1 |
| Kumar, RB | 1 |
| Payne, SL | 1 |
| Ranadive, SA | 1 |
| Suchet, DI | 1 |
| Papadimitriou, DT | 1 |
| Dermitzaki, E | 1 |
| Papagianni, M | 1 |
| Papaioannou, G | 1 |
| Papaevangelou, V | 1 |
| Papadimitriou, A | 1 |
| Hawton, K | 1 |
| Walton-Betancourth, S | 1 |
| Rumsby, G | 1 |
| Raine, J | 1 |
| Dattani, M | 1 |
| Boronat, M | 1 |
| Marrero, D | 1 |
| López-Plasencia, Y | 1 |
| Nóvoa, Y | 1 |
| García-Delgado, Y | 1 |
| Nóvoa, FJ | 1 |
| Mauras, N | 1 |
| Gonzalez de Pijem, L | 1 |
| Hsiang, HY | 1 |
| Desrosiers, P | 1 |
| Rapaport, R | 1 |
| Schwartz, ID | 1 |
| Klein, KO | 1 |
| Singh, RJ | 1 |
| Miyamoto, A | 1 |
| Bishop, K | 1 |
| Faglia, G | 1 |
| Arosio, M | 1 |
| Porretti, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomization to Letrozole vs. Anastrozole in Short Pubertal Males[NCT02137538] | Phase 4 | 79 participants (Actual) | Interventional | 2009-11-18 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Heights will be obtained by physical exam every 6 months during treatment. Skeletal maturation will be assessed from an x-ray by the method of Greulich and Pyle at baseline and every 12 months until the end of treatment.~Predicted adult height will be calculated at baseline and at the end of treatment based upon measured height and skeletal maturation (bone age)." (NCT02137538)
Timeframe: Year 3
| Intervention | cm (Mean) |
|---|---|
| Letrozole | 167.8 |
| Anastrozole | 169.4 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | ng/dL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 37.4 | 77.9 |
| Letrozole | 35.3 | 79.9 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | ng/dL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 19.1 | 44.1 |
| Letrozole | 22.5 | 65.0 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | pg/mL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 4.7 | 6.2 |
| Letrozole | 4.9 | 2.7 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | pg/mL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 8.0 | 3.5 |
| Letrozole | 8.7 | 2.7 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | mIU/mL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 2.5 | 4.5 |
| Letrozole | 3.3 | 6.6 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | pg/mL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 217.0 | 262.1 |
| Letrozole | 203.4 | 257.6 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | ng/mL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 306.9 | 298.7 |
| Letrozole | 306.2 | 226.1 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | mIU/mL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 1.8 | 3.4 |
| Letrozole | 2.3 | 4.7 |
(NCT02137538)
Timeframe: 3 years
| Intervention | events (Number) | |
|---|---|---|
| Acne | Fracture | |
| Anastrozole | 3 | 5 |
| Letrozole | 3 | 3 |
(NCT02137538)
Timeframe: Baseline, year 3
| Intervention | ng/dL (Mean) | |
|---|---|---|
| Baseline | Year 3 | |
| Anastrozole | 162.1 | 680.1 |
| Letrozole | 213.1 | 882.3 |
3 trials available for anastrozole and Stunted Growth
| Article | Year |
|---|---|
Letrozole vs anastrozole for height augmentation in short pubertal males: first year data.
Topics: Adolescent; Anastrozole; Aromatase Inhibitors; Body Height; Child; Estradiol; Growth Disorders; Huma | 2014 |
Anastrozole plus leuprorelin in early maturing girls with compromised growth: the "GAIL" study.
Topics: Anastrozole; Aromatase Inhibitors; Body Height; Bone Density; Case-Control Studies; Child; Female; F | 2016 |
Anastrozole increases predicted adult height of short adolescent males treated with growth hormone: a randomized, placebo-controlled, multicenter trial for one to three years.
Topics: Adolescent; Adult; Age Determination by Skeleton; Anastrozole; Aromatase Inhibitors; Blood Glucose; | 2008 |
5 other studies available for anastrozole and Stunted Growth
| Article | Year |
|---|---|
The effect of anastrozole therapy on final height and sex hormone levels in pubertal boys receiving growth hormone therapy.
Topics: Adult; Anastrozole; Body Height; Growth Disorders; Growth Hormone; Human Growth Hormone; Humans; Inf | 2023 |
Outcome analysis of aromatase inhibitor therapy to increase adult height in males with predicted short adult stature and/or rapid pubertal progress: a retrospective chart review.
Topics: Adolescent; Adult; Age Determination by Skeleton; Anastrozole; Aromatase Inhibitors; Body Height; Bo | 2014 |
Growth Hormone With Aromatase Inhibitor May Improve Height in CYP11B1 Congenital Adrenal Hyperplasia.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Anastrozole; Aromatase Inhibitors; Growth Disorders; Gr | 2017 |
Combined treatment with GH and anastrozole in a pubertal boy with Cushing's disease and postsurgical GH deficiency.
Topics: Adolescent; Anastrozole; Aromatase Inhibitors; Body Height; Drug Therapy, Combination; Growth Disord | 2012 |
Delayed closure of epiphyseal cartilages induced by the aromatase inhibitor anastrozole. Would it help short children grow up?
Topics: Anastrozole; Aromatase Inhibitors; Body Height; Bone Development; Child, Preschool; Enzyme Inhibitor | 2000 |