Page last updated: 2024-10-22

anastrozole and Overweight

anastrozole has been researched along with Overweight in 3 studies

Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.

Research Excerpts

ExcerptRelevanceReference
"Estradiol concentrations in postmenopausal women with early, ER-positive breast cancer on anastrozole were significantly different in normal weight versus overweight or obese patients at baseline, but not at 12 and 24 months."7.80Impact of BMI on serum estradiol and bone turnover markers in postmenopausal women with hormone-sensitive early breast cancer treated with anastrozole. ( Bauer, T; Hadji, P; Hars, O; Knöll, D; Kyvernitakis, I; Struck, M, 2014)
"Estradiol concentrations in postmenopausal women with early, ER-positive breast cancer on anastrozole were significantly different in normal weight versus overweight or obese patients at baseline, but not at 12 and 24 months."3.80Impact of BMI on serum estradiol and bone turnover markers in postmenopausal women with hormone-sensitive early breast cancer treated with anastrozole. ( Bauer, T; Hadji, P; Hars, O; Knöll, D; Kyvernitakis, I; Struck, M, 2014)
"Obesity has been associated with an adverse prognosis and reduced efficacy of endocrine therapy in patients with hormone receptor-positive (HR+) breast cancer (BC)."3.30The prognostic and predictive effect of body mass index in hormone receptor-positive breast cancer. ( de Graaf, H; de Roos, WK; Erdkamp, FLG; Geurts, SME; Honkoop, AH; Imholz, ALT; Kroep, JR; Lammers, SWM; Linn, SC; Smidt, ML; Smorenburg, CH; Swinkels, ACP; Tjan-Heijnen, VCG; van der Sangen, MJC; van Hellemond, IEG; Vriens, IJH, 2023)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Lammers, SWM1
Geurts, SME1
van Hellemond, IEG1
Swinkels, ACP1
Smorenburg, CH1
van der Sangen, MJC1
Kroep, JR1
de Graaf, H1
Honkoop, AH1
Erdkamp, FLG1
de Roos, WK1
Linn, SC1
Imholz, ALT1
Smidt, ML1
Vriens, IJH1
Tjan-Heijnen, VCG1
Gnant, M1
Pfeiler, G1
Stöger, H1
Mlineritsch, B1
Fitzal, F1
Balic, M1
Kwasny, W1
Seifert, M1
Stierer, M1
Dubsky, P1
Greil, R1
Steger, G1
Samonigg, H1
Fesl, C1
Jakesz, R1
Kyvernitakis, I1
Knöll, D1
Struck, M1
Hars, O1
Bauer, T1
Hadji, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Open, Comparative Multicentre Trial of 3 Years Anastrozole Treatment vs. 3 Years no Treatment in Postmenopausal Patients With Breast Cancer Who Have Completed 5 Years Adjuvant Hormone Therapy.[NCT00300508]Phase 3856 participants Interventional1996-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for anastrozole and Overweight

ArticleYear
The prognostic and predictive effect of body mass index in hormone receptor-positive breast cancer.
    JNCI cancer spectrum, 2023, Oct-31, Volume: 7, Issue:6

    Topics: Anastrozole; Body Mass Index; Breast Neoplasms; Female; Humans; Obesity; Overweight; Prognosis

2023
The predictive impact of body mass index on the efficacy of extended adjuvant endocrine treatment with anastrozole in postmenopausal patients with breast cancer: an analysis of the randomised ABCSG-6a trial.
    British journal of cancer, 2013, Aug-06, Volume: 109, Issue:3

    Topics: Adolescent; Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Ind

2013

Other Studies

1 other study available for anastrozole and Overweight

ArticleYear
Impact of BMI on serum estradiol and bone turnover markers in postmenopausal women with hormone-sensitive early breast cancer treated with anastrozole.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:1

    Topics: Anastrozole; Aromatase Inhibitors; Body Mass Index; Bone and Bones; Breast Neoplasms; Collagen Type

2014