Page last updated: 2024-10-22

anastrozole and Endometrioma

anastrozole has been researched along with Endometrioma in 30 studies

Endometrioma: An enlarged area of ENDOMETRIOSIS that resembles a tumor. It is usually found in the OVARY. When it is filled with old blood, it is known as a chocolate cyst.

Research Excerpts

ExcerptRelevanceReference
"Anastrozole 1 mg/day and/or only Mirena® for 6 months; CS (ovarian and fertility-sparing) or TUGPA of endometriomas one month after starting medical treatment."9.41Anastrozole and levonorgrestrel-releasing intrauterine device in the treatment of endometriosis: a randomized clinical trial. ( Acién, M; Acién, P; Velasco, I, 2021)
"Pharmacokinetics (PK) of anastrozole (ATZ) and levonorgestrel (LNG) released from an intravaginal ring (IVR) intended to treat endometriosis symptoms were characterized, and the exposure-response relationship focusing on the development of large ovarian follicle-like structures was investigated by modeling and simulation to support dose selection for further studies."9.24Model-Based Dose Selection for Intravaginal Ring Formulations Releasing Anastrozole and Levonorgestrel Intended for the Treatment of Endometriosis Symptoms. ( Nave, R; Ploeger, BA; Reinecke, I; Schmitz, H; Schultze-Mosgau, MH, 2017)
"Six months of treatment with anastrozole and goserelin as compared to goserelin alone increased the pain-free interval and decreased symptom recurrence rates in patients following surgery for severe endometriosis."9.11The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial. ( Gezgin, T; Gul, N; Ozer, S; Soysal, ME; Soysal, S, 2004)
"In order to achieve the long-term management of endometriosis, a more economical and environmentally friendly material, ethylene vinyl acetate (EVA), was used to prepare a intravaginal ring with anastrozole (ATZ)."8.31A novel anastrozole intravaginal ring for endometriosis: Pharmacokinetic characteristics and mucosal irritation. ( Dong, J; Ma, B; Ning, M; Wu, S; Yang, Z, 2023)
"To study the effects of aromatase inhibitor (anastrozole) on the growth and estradiol secretion of endometrioma cells in culture."7.81Aromatase inhibitor (anastrozole) affects growth of endometrioma cells in culture. ( Badawy, SZ; Brown, S; Kaufman, L; Wojtowycz, MA, 2015)
"Although anastrozole, methotrexate, and progesterone were ineffective, 5-FU significantly decreased the proliferation of endometriotic cells in vitro and controlled the growth of both cells from ovarian endometrioma and deep infiltrating endometriosis."7.76Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo. ( Batteux, F; Chapron, C; Chéreau, C; Leconte, M; Ngô, C; Nicco, C; Weill, B, 2010)
"To compare the efficacies of anastrozole and raloxifene on endometriosis."7.76Comparison of the effects of raloxifene and anastrozole on experimental endometriosis. ( Altintas, D; Cetinkaya, MB; Kandemir, B; Kokcu, A; Tosun, M, 2010)
"Anastrozole 1 mg/day and/or only Mirena® for 6 months; CS (ovarian and fertility-sparing) or TUGPA of endometriomas one month after starting medical treatment."5.41Anastrozole and levonorgrestrel-releasing intrauterine device in the treatment of endometriosis: a randomized clinical trial. ( Acién, M; Acién, P; Velasco, I, 2021)
"Celecoxib was the only treatment to significantly reduce the number of lesions established per mouse, their size and vascularized area."5.39Anastrozole and celecoxib for endometriosis treatment, good to keep them apart? ( Barañao, RI; Bilotas, MA; Meresman, GF; Olivares, CN; Ricci, AG, 2013)
"Pharmacokinetics (PK) of anastrozole (ATZ) and levonorgestrel (LNG) released from an intravaginal ring (IVR) intended to treat endometriosis symptoms were characterized, and the exposure-response relationship focusing on the development of large ovarian follicle-like structures was investigated by modeling and simulation to support dose selection for further studies."5.24Model-Based Dose Selection for Intravaginal Ring Formulations Releasing Anastrozole and Levonorgestrel Intended for the Treatment of Endometriosis Symptoms. ( Nave, R; Ploeger, BA; Reinecke, I; Schmitz, H; Schultze-Mosgau, MH, 2017)
"Prolonged combined anastrozole and goserelin down-regulation significantly reduces endometriomal volume and serum CA125, and is compatible with IVF pregnancy and delivery."5.14Combined down-regulation by aromatase inhibitor and GnRH-agonist in IVF patients with endometriomas-A pilot study. ( Andersen, AN; Andersen, CY; Bangsbøll, S; Freiesleben, NL; Hartwell, D; Loft, A; Lossl, K; Pedersen, AT, 2009)
"Six months of treatment with anastrozole and goserelin as compared to goserelin alone increased the pain-free interval and decreased symptom recurrence rates in patients following surgery for severe endometriosis."5.11The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial. ( Gezgin, T; Gul, N; Ozer, S; Soysal, ME; Soysal, S, 2004)
"In order to achieve the long-term management of endometriosis, a more economical and environmentally friendly material, ethylene vinyl acetate (EVA), was used to prepare a intravaginal ring with anastrozole (ATZ)."4.31A novel anastrozole intravaginal ring for endometriosis: Pharmacokinetic characteristics and mucosal irritation. ( Dong, J; Ma, B; Ning, M; Wu, S; Yang, Z, 2023)
"To study the effects of aromatase inhibitor (anastrozole) on the growth and estradiol secretion of endometrioma cells in culture."3.81Aromatase inhibitor (anastrozole) affects growth of endometrioma cells in culture. ( Badawy, SZ; Brown, S; Kaufman, L; Wojtowycz, MA, 2015)
"Although anastrozole, methotrexate, and progesterone were ineffective, 5-FU significantly decreased the proliferation of endometriotic cells in vitro and controlled the growth of both cells from ovarian endometrioma and deep infiltrating endometriosis."3.76Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo. ( Batteux, F; Chapron, C; Chéreau, C; Leconte, M; Ngô, C; Nicco, C; Weill, B, 2010)
"To compare the efficacies of anastrozole and raloxifene on endometriosis."3.76Comparison of the effects of raloxifene and anastrozole on experimental endometriosis. ( Altintas, D; Cetinkaya, MB; Kandemir, B; Kokcu, A; Tosun, M, 2010)
"Four premenopausal patients with documented refractory endometriosis and chronic pelvic pain were treated with aromatase inhibitors, either anastrazole (3) or letrozole (1), for 6 months."3.75Successful treatment of refractory endometriosis-related chronic pelvic pain with aromatase inhibitors in premenopausal patients. ( Konje, JC; Verma, A, 2009)
"This is the first case report of successful treatment of severe endometriosis in premenopausal women with the aromatase inhibitor anastrozole combined with P, rofecoxib, and calcitriol."3.72Successful treatment of severe endometriosis in two premenopausal women with an aromatase inhibitor. ( Shippen, ER; West, WJ, 2004)
"This treatment for endometriosis is a promising new modality that warrants further investigation."2.71Anastrazole and oral contraceptives: a novel treatment for endometriosis. ( Amsterdam, LL; Bulun, SE; Gentry, W; Jobanputra, S; Rubin, SD; Wolf, M, 2005)
"Endometriosis is defined as the growth of endometrial tissue outside of the uterine cavity."2.47The emerging use of aromatase inhibitors for endometriosis treatment. ( Nothnick, WB, 2011)
" Since endometriosis is a chronic disease, future investigations should clarify whether the long-term administration of AIs is superior to currently available endocrine therapies in terms of improvement of pain, adverse effects and patient satisfaction."2.47Use of aromatase inhibitors to treat endometriosis-related pain symptoms: a systematic review. ( Ferrero, S; Gillott, DJ; Remorgida, V; Venturini, PL, 2011)
"Endometriosis is an enigmatic, debilitating disease which affects as many as 15% of all women of reproductive age and is characterized by pelvic pain and infertility."2.46Endometriosis: in search of optimal treatment. ( Nothnick, WB, 2010)
"Endometriosis is an enigmatic, debilitating disease which affects as many as 15% of all women of reproductive age and is characterized by pelvic pain and infertility."2.45Future targets in endometriosis treatment: targeting the endometriotic implant. ( Nothnick, WB; Zhang, X, 2009)
"Endometriosis is a relatively common condition in women of reproductive age and is associated with considerable morbidity."2.43Endometriosis: new genetic approaches and therapy. ( Barlow, DH; Kennedy, S, 2005)
"Endometriosis is an oestrogen-dependent, inflammation-driven gynaecologic disorder causing severe disability."1.51Effect of local aromatase inhibition in endometriosis using a new chick embryo chorioallantoic membrane model. ( Cohen, M; Marci, R; Pluchino, N; Poppi, G; Tille, JC; Wenger, JM; Yart, L, 2019)
" Long-term use of gonadotrophin-releasing hormone analogs, androgenes, and the danazol, which are widely used drugs for endometriosis, is usually not possible due to their suboptimal safety and tolerance profile."1.43Effect of imatinib on growth of experimental endometriosis in rats. ( Akkar, OB; Cetin, A; Kacan, SB; Kacan, T; Karakus, S; Ozer, H; Seker, M; Yildiz, C, 2016)
"Celecoxib was the only treatment to significantly reduce the number of lesions established per mouse, their size and vascularized area."1.39Anastrozole and celecoxib for endometriosis treatment, good to keep them apart? ( Barañao, RI; Bilotas, MA; Meresman, GF; Olivares, CN; Ricci, AG, 2013)
"Treatment with anastrozole or letrozole was started on either postoperative day 1 or 28 and continued for 4 weeks."1.36Effect of aromatase inhibitors on ectopic endometrial growth and peritoneal environment in a mouse model of endometriosis. ( Barañao, RI; Bilotas, M; Meresman, G; Stella, I; Sueldo, C, 2010)
"Anastrozole was ineffective at preventing deterioration of renal function in this patient."1.35Persistent bilateral ureteral obstruction secondary to endometriosis despite treatment with an aromatase inhibitor. ( Bohrer, J; Chen, CC; Falcone, T, 2008)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.33)18.2507
2000's12 (40.00)29.6817
2010's15 (50.00)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Thomas, MP1
Potter, BV1
Yang, Z1
Dong, J1
Wu, S1
Ma, B1
Ning, M1
Acién, P1
Velasco, I1
Acién, M1
Nave, R3
Klein, S2
Müller, A1
Chang, X1
Höchel, J1
Pluchino, N1
Poppi, G1
Yart, L1
Marci, R1
Wenger, JM1
Tille, JC1
Cohen, M1
Badawy, SZ1
Brown, S1
Kaufman, L1
Wojtowycz, MA1
Yildiz, C1
Kacan, T1
Akkar, OB1
Karakus, S1
Seker, M1
Kacan, SB1
Ozer, H1
Cetin, A1
Schultze-Mosgau, MH2
Waellnitz, K1
Kraetzschmar, J1
Rautenberg, T1
Schmitz, H2
Rohde, B1
Reinecke, I1
Ploeger, BA1
Bohrer, J1
Chen, CC1
Falcone, T1
Verma, A1
Konje, JC1
Lossl, K1
Loft, A1
Freiesleben, NL1
Bangsbøll, S1
Andersen, CY1
Pedersen, AT1
Hartwell, D1
Andersen, AN1
Nothnick, WB3
Zhang, X1
Vercellini, P1
Crosignani, PG1
Somigliana, E1
Berlanda, N1
Barbara, G1
Fedele, L1
Bilotas, M1
Meresman, G1
Stella, I1
Sueldo, C1
Barañao, RI2
Ngô, C1
Nicco, C1
Leconte, M1
Chéreau, C1
Weill, B1
Batteux, F1
Chapron, C1
Altintas, D1
Kokcu, A1
Kandemir, B1
Tosun, M1
Cetinkaya, MB1
Li, A1
Wang, Y1
Xu, XY1
Ferrero, S1
Gillott, DJ1
Venturini, PL1
Remorgida, V1
Olivares, CN1
Bilotas, MA1
Ricci, AG1
Meresman, GF1
Soysal, S1
Soysal, ME1
Ozer, S1
Gul, N1
Gezgin, T1
Shippen, ER1
West, WJ1
Barlow, DH1
Kennedy, S1
Amsterdam, LL1
Gentry, W1
Jobanputra, S1
Wolf, M1
Rubin, SD1
Bulun, SE4
Hefler, LA1
Grimm, C1
van Trotsenburg, M1
Nagele, F1
Takayama, K3
Zeitoun, K1
Gunby, RT1
Sasano, H2
Carr, BR1
Zeitoun, KM1

Reviews

8 reviews available for anastrozole and Endometrioma

ArticleYear
Future targets in endometriosis treatment: targeting the endometriotic implant.
    Mini reviews in medicinal chemistry, 2009, Volume: 9, Issue:3

    Topics: Anastrozole; Angiogenesis Inhibitors; Animals; Aromatase Inhibitors; Clinical Trials as Topic; Endom

2009
Medical treatment for rectovaginal endometriosis: what is the evidence?
    Human reproduction (Oxford, England), 2009, Volume: 24, Issue:10

    Topics: Anastrozole; Aromatase Inhibitors; Cohort Studies; Danazol; Endometriosis; Female; Gonadotropin-Rele

2009
Endometriosis: in search of optimal treatment.
    Minerva ginecologica, 2010, Volume: 62, Issue:1

    Topics: Adalimumab; Anastrozole; Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antibodie

2010
The emerging use of aromatase inhibitors for endometriosis treatment.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Anastrozole; Animals; Aromatase Inhibitors; Disease Models, Animal; Endometriosis; Endometrium; Estr

2011
Use of aromatase inhibitors to treat endometriosis-related pain symptoms: a systematic review.
    Reproductive biology and endocrinology : RB&E, 2011, Jun-21, Volume: 9

    Topics: Anastrozole; Aromatase Inhibitors; Clinical Trials as Topic; Endometriosis; Female; Humans; Letrozol

2011
Endometriosis: new genetic approaches and therapy.
    Annual review of medicine, 2005, Volume: 56

    Topics: Anastrozole; Aromatase Inhibitors; Drug Therapy, Combination; Endometriosis; Endometrium; Female; Ge

2005
Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance.
    Journal of molecular endocrinology, 2000, Volume: 25, Issue:1

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estrog

2000
[Endometriosis and aromatase inhibitor].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 1

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estrog

2001

Trials

7 trials available for anastrozole and Endometrioma

ArticleYear
Anastrozole and levonorgrestrel-releasing intrauterine device in the treatment of endometriosis: a randomized clinical trial.
    BMC women's health, 2021, 05-20, Volume: 21, Issue:1

    Topics: Anastrozole; Contraceptive Agents, Female; Endometriosis; Female; Humans; Intrauterine Devices; Intr

2021
Absence of Effect of Intravaginal Miconazole, Clindamycin, Nonoxynol-9, and Tampons on the Pharmacokinetics of an Anastrozole/Levonorgestrel Intravaginal Ring.
    Journal of clinical pharmacology, 2018, Volume: 58, Issue:1

    Topics: Administration, Intravaginal; Adult; Anastrozole; Anti-Bacterial Agents; Antifungal Agents; Clindamy

2018
Pharmacokinetics, pharmacodynamics, safety and tolerability of an intravaginal ring releasing anastrozole and levonorgestrel in healthy premenopausal women: a Phase 1 randomized controlled trial.
    Human reproduction (Oxford, England), 2016, Volume: 31, Issue:8

    Topics: Administration, Intravaginal; Adult; Anastrozole; Aromatase Inhibitors; Endometriosis; Estradiol; Fe

2016
Model-Based Dose Selection for Intravaginal Ring Formulations Releasing Anastrozole and Levonorgestrel Intended for the Treatment of Endometriosis Symptoms.
    Journal of clinical pharmacology, 2017, Volume: 57, Issue:5

    Topics: Administration, Intravaginal; Adult; Anastrozole; Computer Simulation; Contraceptive Agents, Female;

2017
Combined down-regulation by aromatase inhibitor and GnRH-agonist in IVF patients with endometriomas-A pilot study.
    European journal of obstetrics, gynecology, and reproductive biology, 2009, Volume: 144, Issue:1

    Topics: Adult; Anastrozole; Aromatase Inhibitors; CA-125 Antigen; Down-Regulation; Drug Therapy, Combination

2009
The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial.
    Human reproduction (Oxford, England), 2004, Volume: 19, Issue:1

    Topics: Adult; Anastrozole; Aromatase Inhibitors; Bone Density; Drug Administration Schedule; Drug Therapy,

2004
Anastrazole and oral contraceptives: a novel treatment for endometriosis.
    Fertility and sterility, 2005, Volume: 84, Issue:2

    Topics: Adult; Anastrozole; Contraceptives, Oral; Drug Therapy, Combination; Endometriosis; Female; Humans;

2005

Other Studies

15 other studies available for anastrozole and Endometrioma

ArticleYear
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
    Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Discovery; Endometriosi

2015
A novel anastrozole intravaginal ring for endometriosis: Pharmacokinetic characteristics and mucosal irritation.
    Biomedical chromatography : BMC, 2023, Volume: 37, Issue:6

    Topics: Anastrozole; Animals; Chromatography, Liquid; Endometriosis; Female; Humans; Reproducibility of Resu

2023
Effect of local aromatase inhibition in endometriosis using a new chick embryo chorioallantoic membrane model.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:8

    Topics: Anastrozole; Animals; Aromatase Inhibitors; Cell Proliferation; Chick Embryo; Chorioallantoic Membra

2019
Aromatase inhibitor (anastrozole) affects growth of endometrioma cells in culture.
    European journal of obstetrics, gynecology, and reproductive biology, 2015, Volume: 188

    Topics: Anastrozole; Aromatase Inhibitors; Cell Proliferation; Cells, Cultured; Endometriosis; Estradiol; Fe

2015
Effect of imatinib on growth of experimental endometriosis in rats.
    European journal of obstetrics, gynecology, and reproductive biology, 2016, Volume: 197

    Topics: Anastrozole; Angiogenesis Inhibitors; Animals; Aromatase Inhibitors; bcl-2-Associated X Protein; Cel

2016
Persistent bilateral ureteral obstruction secondary to endometriosis despite treatment with an aromatase inhibitor.
    Fertility and sterility, 2008, Volume: 90, Issue:5

    Topics: Anastrozole; Aromatase Inhibitors; Disease Progression; Endometriosis; Female; Humans; Kidney Functi

2008
Successful treatment of refractory endometriosis-related chronic pelvic pain with aromatase inhibitors in premenopausal patients.
    European journal of obstetrics, gynecology, and reproductive biology, 2009, Volume: 143, Issue:2

    Topics: Adult; Anastrozole; Aromatase Inhibitors; Chronic Disease; Dose-Response Relationship, Drug; Endomet

2009
Effect of aromatase inhibitors on ectopic endometrial growth and peritoneal environment in a mouse model of endometriosis.
    Fertility and sterility, 2010, May-15, Volume: 93, Issue:8

    Topics: Anastrozole; Animals; Apoptosis; Aromatase; Aromatase Inhibitors; Ascitic Fluid; Cell Proliferation;

2010
Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo.
    Fertility and sterility, 2010, Volume: 94, Issue:5

    Topics: Adult; Anastrozole; Animals; Antineoplastic Agents; Biopsy; Case-Control Studies; Cell Proliferation

2010
Comparison of the effects of raloxifene and anastrozole on experimental endometriosis.
    European journal of obstetrics, gynecology, and reproductive biology, 2010, Volume: 150, Issue:1

    Topics: Anastrozole; Animals; Aromatase Inhibitors; Disease Models, Animal; Endometriosis; Female; Nitriles;

2010
[Inhibitory effect of Jiawei Sanleng pill medicated serum on estrogen production and its influence on apoptosis of human endometrial cells of endometriosis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:3

    Topics: Anastrozole; Animals; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Drugs, Chinese H

2010
Anastrozole and celecoxib for endometriosis treatment, good to keep them apart?
    Reproduction (Cambridge, England), 2013, Volume: 145, Issue:2

    Topics: Anastrozole; Animals; Aromatase Inhibitors; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Combination

2013
Successful treatment of severe endometriosis in two premenopausal women with an aromatase inhibitor.
    Fertility and sterility, 2004, Volume: 81, Issue:5

    Topics: Adult; Anastrozole; Aromatase Inhibitors; Drug Therapy, Combination; Endometriosis; Enzyme Inhibitor

2004
Role of the vaginally administered aromatase inhibitor anastrozole in women with rectovaginal endometriosis: a pilot study.
    Fertility and sterility, 2005, Volume: 84, Issue:4

    Topics: Administration, Intravaginal; Adult; Anastrozole; Aromatase Inhibitors; Chi-Square Distribution; End

2005
Treatment of severe postmenopausal endometriosis with an aromatase inhibitor.
    Fertility and sterility, 1998, Volume: 69, Issue:4

    Topics: Administration, Oral; Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Biopsy; Endometriosis;

1998