Page last updated: 2024-10-22

anastrozole and Cognition Disorders

anastrozole has been researched along with Cognition Disorders in 10 studies

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
" This phase III open-label study compared the impact of tamoxifen and AI on verbal episodic memory (Rey auditory verbal learning test-RAVLT) and other cognitive functions (visual memory, psychomotor speed, and executive functions) after 6 and 12 months of treatment in breast cancer patients undergoing adjuvant hormonotherapy."5.20A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy. ( Bonneterre, J; Delbeuck, X; Kramar, A; Le Rhun, E; Lefeuvre-Plesse, C; Pasquier, F; Skrobala, E, 2015)
" Breast cancer was diagnosed in 2013 and she has been receiving anastrozole treatment for 6 years after local mass excision surgery and radiotherapy."3.96The Effect of Theracurmin on Cognitive Function in an Older Patient with Chemobrain. ( Dost Gunay, FS; Erken, N; Isik, AT; Soysal, P, 2020)
"Androstenedione, the main circulating ovarian hormone present after menopause, has been shown to positively correlate with poor spatial memory in an ovary-intact rodent model of follicular depletion, and to impair spatial memory when administered exogenously to surgically menopausal ovariectomized rats."3.81Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats. ( Acosta, JI; Alderete, TJ; Bimonte-Nelson, HA; Camp, BW; Demers, LM; Koebele, SV; Mennenga, SE; Mousa, AA; Tsang, CW, 2015)
"The purpose of this study was to examine and compare the effects of the first 18 months of anastrozole therapy on cognitive function in women with breast cancer."3.81Patterns of change in cognitive function with anastrozole therapy. ( Ahrendt, GM; Bender, CM; Berga, SL; Brufsky, AM; Casillo, FE; Dailey, MM; Erickson, KI; Gentry, AL; Kratofil, FM; McAuliffe, PF; Merriman, JD; Rosenzweig, MQ; Ryan, CM; Sereika, SM, 2015)
", tamoxifen and anastrozole) on cognitive functioning by comparing 28 postmenopausal women with breast cancer to 37 healthy age-equivalent controls."3.76Endocrine therapy is associated with low performance on some estrogen-sensitive cognitive tasks in postmenopausal women with breast cancer. ( Crossley, M; Lejbak, L; Vrbancic, M, 2010)
"Post-menopausal breast cancer patients scheduled to receive tamoxifen (n=31) or anastrozole (n=14) completed neuropsychological testing around the time of commencement of treatment (T1), and again 5-6 months later (T2)."3.75Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study. ( Bielajew, C; Collins, B; Mackenzie, J; Stewart, A; Verma, S, 2009)
"Endocrine therapy in the setting of breast cancer has undoubtedly advanced clinical outcomes in this disease, but treatment with endocrine therapy is accompanied by a wide spectrum of side effects."1.36Cognitive changes associated with endocrine therapy for breast cancer. ( Agrawal, K; Mortimer, JE; Onami, S; Pal, SK, 2010)
" As a result, the long-term use of anti-oestrogens may have potential consequences for cognition."1.32The effects of hormone therapy on cognition in breast cancer. ( Fallowfield, L; Howell, T; Jenkins, V; Shilling, V, 2003)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Erken, N1
Dost Gunay, FS1
Soysal, P1
Isik, AT1
Bender, CM2
Merriman, JD2
Sereika, SM2
Gentry, AL2
Casillo, FE2
Koleck, TA1
Rosenzweig, MQ2
Brufsky, AM2
McAuliffe, P1
Zhu, Y1
Conley, YP1
Mennenga, SE1
Koebele, SV1
Mousa, AA1
Alderete, TJ1
Tsang, CW1
Acosta, JI1
Camp, BW1
Demers, LM1
Bimonte-Nelson, HA1
Ahrendt, GM1
Berga, SL1
Dailey, MM1
Erickson, KI1
Kratofil, FM1
McAuliffe, PF1
Ryan, CM1
Le Rhun, E1
Delbeuck, X1
Lefeuvre-Plesse, C1
Kramar, A1
Skrobala, E1
Pasquier, F1
Bonneterre, J1
Collins, B1
Mackenzie, J1
Stewart, A1
Bielajew, C1
Verma, S1
Lejbak, L1
Vrbancic, M1
Crossley, M1
Agrawal, K1
Onami, S1
Mortimer, JE1
Pal, SK1
Shilling, V2
Jenkins, V2
Fallowfield, L2
Howell, T1
Howell, A1
Hutton, S1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Longitudinal Investigation of the Neuropsychological and Psychosocial Effects of Cancer Therapy[NCT00260975]112 participants (Actual)Observational2001-06-30Completed
The Relationship Between Biopsychosocial Functioning and Work-Related Cognitive Limitation Among Employed Breast Cancer Survivors: Case Control Study.[NCT02303145]187 participants (Actual)Observational2014-09-30Completed
Chemotherapy-Related Changes in Neurocognitive Function and Symptoms in Colorectal Cancer Patients: A Pilot Study[NCT03683004]40 participants (Actual)Observational2018-01-22Completed
Treating Verbal Memory Deficits Following Chemotherapy for Breast Cancer[NCT03017560]45 participants (Actual)Interventional2015-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for anastrozole and Cognition Disorders

ArticleYear
A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy.
    Breast cancer research and treatment, 2015, Volume: 152, Issue:3

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neo

2015
Does hormone therapy for the treatment of breast cancer have a detrimental effect on memory and cognition? A pilot study.
    Psycho-oncology, 2004, Volume: 13, Issue:1

    Topics: Affect; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Anxiet

2004

Other Studies

8 other studies available for anastrozole and Cognition Disorders

ArticleYear
The Effect of Theracurmin on Cognitive Function in an Older Patient with Chemobrain.
    Clinical interventions in aging, 2020, Volume: 15

    Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cognition; Cognition Disorders

2020
Trajectories of Cognitive Function and Associated Phenotypic and Genotypic Factors in Breast Cancer.
    Oncology nursing forum, 2018, 05-01, Volume: 45, Issue:3

    Topics: Adult; Age Factors; Aged; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuva

2018
Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats.
    Steroids, 2015, Volume: 99, Issue:Pt A

    Topics: Anastrozole; Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Brain; Cognition

2015
Patterns of change in cognitive function with anastrozole therapy.
    Cancer, 2015, Aug-01, Volume: 121, Issue:15

    Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols;

2015
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
    Psycho-oncology, 2009, Volume: 18, Issue:8

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Diso

2009
Endocrine therapy is associated with low performance on some estrogen-sensitive cognitive tasks in postmenopausal women with breast cancer.
    Journal of clinical and experimental neuropsychology, 2010, Volume: 32, Issue:8

    Topics: Aged; Anastrozole; Breast Neoplasms; Case-Control Studies; Cognition Disorders; Estrogen Antagonists

2010
Cognitive changes associated with endocrine therapy for breast cancer.
    Maturitas, 2010, Volume: 67, Issue:3

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy P

2010
The effects of hormone therapy on cognition in breast cancer.
    The Journal of steroid biochemistry and molecular biology, 2003, Volume: 86, Issue:3-5

    Topics: Affect; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combin

2003