Page last updated: 2024-10-22

anastrozole and Carcinoma, Intraductal, Noninfiltrating

anastrozole has been researched along with Carcinoma, Intraductal, Noninfiltrating in 13 studies

Carcinoma, Intraductal, Noninfiltrating: A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma.

Research Excerpts

ExcerptRelevanceReference
" Postmenopausal women at increased risk of developing breast cancer were recruited and were randomly assigned (1:1) to either anastrozole (1 mg per day, oral) or matching placebo daily for 5 years."9.34Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial. ( Bonanni, B; Cawthorn, S; Cuzick, J; Dowsett, M; Evans, DG; Forbes, JF; Howell, A; Loibl, S; Mansel, RE; Sestak, I, 2020)
"Anastrozole reduces breast cancer risk in women at high risk, but implementing preventive therapy in clinical practice is difficult."9.27Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II. ( Cuzick, J; Forbes, JF; Howell, A; Sestak, I; Smith, SG, 2018)
"Anastrozole effectively reduces incidence of breast cancer in high-risk postmenopausal women."9.19Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial. ( Bonanni, B; Cawthorn, S; Cuzick, J; Dowsett, M; Forbes, JF; Howell, A; Knox, J; Mansel, RE; Palva, T; Roche, N; Saunders, C; Sestak, I; von Minckwitz, G, 2014)
"The primary end point is breast cancer incidence, but major efforts are also being directed at minimizing any fracture risk."5.35IBIS II: a breast cancer prevention trial in postmenopausal women using the aromatase inhibitor anastrozole. ( Cuzick, J, 2008)
" Postmenopausal women at increased risk of developing breast cancer were recruited and were randomly assigned (1:1) to either anastrozole (1 mg per day, oral) or matching placebo daily for 5 years."5.34Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial. ( Bonanni, B; Cawthorn, S; Cuzick, J; Dowsett, M; Evans, DG; Forbes, JF; Howell, A; Loibl, S; Mansel, RE; Sestak, I, 2020)
"Anastrozole reduces breast cancer risk in women at high risk, but implementing preventive therapy in clinical practice is difficult."5.27Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II. ( Cuzick, J; Forbes, JF; Howell, A; Sestak, I; Smith, SG, 2018)
"Anastrozole effectively reduces incidence of breast cancer in high-risk postmenopausal women."5.19Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial. ( Bonanni, B; Cawthorn, S; Cuzick, J; Dowsett, M; Forbes, JF; Howell, A; Knox, J; Mansel, RE; Palva, T; Roche, N; Saunders, C; Sestak, I; von Minckwitz, G, 2014)
"This study piloted a DA booklet for a high priority breast cancer prevention trial, IBIS-II DCIS, which compares the efficacy of an aromatase inhibitor (anastrozole) with tamoxifen in women who have had surgery for ductal carcinoma in situ (DCIS)."5.13Improving informed consent: pilot of a decision aid for women invited to participate in a breast cancer prevention trial (IBIS-II DCIS). ( Boyle, F; Butow, P; Coates, A; Forbes, JF; Juraskova, I; Lopez, A; McCarthy, N; Reaby, L; Seccombe, M, 2008)
"Although tamoxifen has been the gold standard of HT for breast cancer, results of ongoing trials assessing the newer HTs as initial, neoadjuvant, adjuvant, and chemopreventive therapies may substantially change our current clinical practice patterns."4.81Evolving uses of hormonal agents for breast cancer therapy. ( Cummings, FJ, 2002)
"The management of ductal carcinoma in situ (DCIS) with endocrine therapy remains controversial."2.66Endocrine Therapy for Ductal Carcinoma In Situ (DCIS) of the Breast with Breast Conserving Surgery (BCS) and Radiotherapy (RT): a Meta-Analysis. ( Drokow, EK; Li, Z; Liu, J; Ma, X; Ren, J; Shao, S; Shi, X; Tan, L; Xue, C; Yan, Y; Zhang, L; Zhang, X; Zhang, Y, 2020)
"However, concern for under- or over-treatment of DCIS has led many surgeons to question historically standardized approaches and instead begin to tailor treatment based on individual prognostic indicators."2.52Ductal Carcinoma In Situ: Treatment Update and Current Trends. ( Kuerer, H; Mitchell, KB, 2015)
"The primary end point is breast cancer incidence, but major efforts are also being directed at minimizing any fracture risk."1.35IBIS II: a breast cancer prevention trial in postmenopausal women using the aromatase inhibitor anastrozole. ( Cuzick, J, 2008)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Kantor, O1
King, TA1
Jones, A1
Glass, C1
Leonard, SJ1
Ogayo, ER1
Mayer, EL1
Chavez-MacGregor, M1
Newman, LA1
Freedman, RA1
Mittendorf, EA1
Cuzick, J4
Sestak, I3
Forbes, JF4
Dowsett, M2
Cawthorn, S2
Mansel, RE2
Loibl, S1
Bonanni, B2
Evans, DG1
Howell, A3
Smith, SG1
Yan, Y1
Zhang, L1
Tan, L1
Ma, X1
Zhang, Y1
Shao, S1
Liu, J1
Xue, C1
Li, Z1
Zhang, X1
Drokow, EK1
Shi, X1
Ren, J1
Cameron, DA1
Knox, J1
Saunders, C1
Roche, N1
von Minckwitz, G1
Palva, T1
Mitchell, KB1
Kuerer, H1
Saha, P1
Amico, AL1
Olopade, OI1
Juraskova, I1
Butow, P1
Lopez, A1
Seccombe, M1
Coates, A1
Boyle, F1
McCarthy, N1
Reaby, L1
Cummings, FJ1
Thornton, H1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
International Breast Cancer Intervention Study[NCT00078832]Phase 33,864 participants (Actual)Interventional2003-09-30Completed
International Breast Cancer Intervention Study II (IBIS-II) (DCIS)[NCT00072462]Phase 32,980 participants (Actual)Interventional2003-09-30Completed
Effects of Progressive Relaxation Training on Artralgia, Quality of Life and Emotional Status in Breast Cancer Patients Receiving Aromatatase Inhibitor Therapy[NCT04163692]44 participants (Actual)Interventional2019-10-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for anastrozole and Carcinoma, Intraductal, Noninfiltrating

ArticleYear
Endocrine Therapy for Ductal Carcinoma In Situ (DCIS) of the Breast with Breast Conserving Surgery (BCS) and Radiotherapy (RT): a Meta-Analysis.
    Pathology oncology research : POR, 2020, Volume: 26, Issue:1

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrat

2020
Ductal Carcinoma In Situ: Treatment Update and Current Trends.
    Current oncology reports, 2015, Volume: 17, Issue:11

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrat

2015
Evolving uses of hormonal agents for breast cancer therapy.
    Clinical therapeutics, 2002, Volume: 24 Suppl C

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrat

2002

Trials

5 trials available for anastrozole and Carcinoma, Intraductal, Noninfiltrating

ArticleYear
Racial and Ethnic Disparities in Outcomes After Breast-Conserving Therapy and Endocrine Therapy for DCIS: A Post-Hoc Analysis of the NSABP B-35 Randomized Clinical Trial.
    Annals of surgical oncology, 2023, Volume: 30, Issue:13

    Topics: Anastrozole; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Ethnicity; Female; Humans; T

2023
Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial.
    Lancet (London, England), 2020, 01-11, Volume: 395, Issue:10218

    Topics: Administration, Oral; Adult; Aged; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, D

2020
Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 02-01, Volume: 29, Issue:2

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal,

2018
Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 02-01, Volume: 29, Issue:2

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal,

2018
Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 02-01, Volume: 29, Issue:2

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal,

2018
Early participant-reported symptoms as predictors of adherence to anastrozole in the International Breast Cancer Intervention Studies II.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2018, 02-01, Volume: 29, Issue:2

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal,

2018
Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial.
    Lancet (London, England), 2014, Mar-22, Volume: 383, Issue:9922

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; C

2014
Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial.
    Lancet (London, England), 2014, Mar-22, Volume: 383, Issue:9922

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; C

2014
Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial.
    Lancet (London, England), 2014, Mar-22, Volume: 383, Issue:9922

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; C

2014
Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial.
    Lancet (London, England), 2014, Mar-22, Volume: 383, Issue:9922

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; C

2014
Improving informed consent: pilot of a decision aid for women invited to participate in a breast cancer prevention trial (IBIS-II DCIS).
    Health expectations : an international journal of public participation in health care and health policy, 2008, Volume: 11, Issue:3

    Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Australia;

2008

Other Studies

5 other studies available for anastrozole and Carcinoma, Intraductal, Noninfiltrating

ArticleYear
Breast cancer chemoprevention: little progress in practice?
    Lancet (London, England), 2014, Mar-22, Volume: 383, Issue:9922

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Duc

2014
Long-Term Disease-Free Survival in a Young Patient With Hormone Receptor-Positive Breast Cancer and Oligometastatic Disease in the Brain.
    Clinical breast cancer, 2016, Volume: 16, Issue:3

    Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carc

2016
IBIS II: a breast cancer prevention trial in postmenopausal women using the aromatase inhibitor anastrozole.
    Expert review of anticancer therapy, 2008, Volume: 8, Issue:9

    Topics: Adult; Aged; Anastrozole; Aromatase Inhibitors; Bone Density Conservation Agents; Breast Neoplasms;

2008
NCCN Guideline update: Breast Cancer Version 1.2004.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2004, Volume: 2, Issue:3

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrat

2004
Anastrozole as a preventive agent in breast cancer.
    Lancet (London, England), 2003, May-31, Volume: 361, Issue:9372

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrat

2003