anastrozole has been researched along with Cancer of Endometrium in 28 studies
Excerpt | Relevance | Reference |
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"To investigate whether there may be a role for aromatase inhibitors (AIs) in the treatment of endometrial hyperplasia (EH) and endometrial adenocarcinoma (EA) in postmenopausal women, a retrospective study on the effect of aromatase inhibitors (anastrozole or letrozole) was conducted for 16 patients who were not amenable to surgical treatment." | 7.75 | Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma. ( Barker, LC; Brand, IR; Crawford, SM, 2009) |
"Tamoxifen treatment results in a doubling of the risk of endometrial cancer after 1-2 years of treatment and a quadrupling after 5 years." | 6.72 | The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) adjuvant breast cancer trial: first results of the endometrial sub-protocol following 2 years of treatment. ( Bianco, AR; Clack, G; Coibion, M; Duffy, S; Jackson, TL; Lansdown, M; Philips, K; Pollard, S; Wells, M, 2006) |
"Anastrozole (Arimidex) is an oral nonsteroidal aromatase inhibitor which is active in recurrent breast cancer." | 6.69 | A phase II trial of anastrozole in advanced recurrent or persistent endometrial carcinoma: a Gynecologic Oncology Group study. ( Bell, J; Brunetto, VL; Lee, RB; Rose, PG; VanLe, L; Walker, JL, 2000) |
"Fulvestrant is a new type of oestrogen receptor antagonist with no agonist effects." | 6.43 | Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents. ( Abram, P; Vergote, I, 2006) |
"To investigate whether there may be a role for aromatase inhibitors (AIs) in the treatment of endometrial hyperplasia (EH) and endometrial adenocarcinoma (EA) in postmenopausal women, a retrospective study on the effect of aromatase inhibitors (anastrozole or letrozole) was conducted for 16 patients who were not amenable to surgical treatment." | 3.75 | Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma. ( Barker, LC; Brand, IR; Crawford, SM, 2009) |
"This multicenter, open-label, phase 1/2 randomized clinical trial demonstrated that adding vistusertib to anastrozole improved 8wk-PFR, overall response rate, and PFS for patients with endometrial cancer and had manageable adverse events." | 3.11 | Safety and Efficacy of the mTOR Inhibitor, Vistusertib, Combined With Anastrozole in Patients With Hormone Receptor-Positive Recurrent or Metastatic Endometrial Cancer: The VICTORIA Multicenter, Open-label, Phase 1/2 Randomized Clinical Trial. ( Abdeddaim, C; Arnaud, A; Augereau, P; Bazan, F; Chakiba, C; Chevalier-Place, A; Dalban, C; Diaz, JJ; Fabbro, M; Frenel, JS; Garin, G; Heudel, P; Joly, F; Lancry-Lecomte, L; Marcel, V; Pautier, P; Pérol, D; Ray-Coquard, I; Treilleux, I; You, B, 2022) |
"Patients with endometrial cancer who consented to participate in the study were randomised to receive anastrozole or placebo for a minimum of 14 days prior to definitive surgery." | 2.78 | Neoadjuvant treatment of endometrial cancer using anastrozole: a randomised pilot study. ( Duffy, SR; Hewitt, MJ; Quinton, ND; Thangavelu, A, 2013) |
"Tamoxifen treatment results in a doubling of the risk of endometrial cancer after 1-2 years of treatment and a quadrupling after 5 years." | 2.72 | The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) adjuvant breast cancer trial: first results of the endometrial sub-protocol following 2 years of treatment. ( Bianco, AR; Clack, G; Coibion, M; Duffy, S; Jackson, TL; Lansdown, M; Philips, K; Pollard, S; Wells, M, 2006) |
"Anastrozole (Arimidex) is an oral nonsteroidal aromatase inhibitor which is active in recurrent breast cancer." | 2.69 | A phase II trial of anastrozole in advanced recurrent or persistent endometrial carcinoma: a Gynecologic Oncology Group study. ( Bell, J; Brunetto, VL; Lee, RB; Rose, PG; VanLe, L; Walker, JL, 2000) |
"Type I endometrial cancer is a common tumor of the female genital tract." | 2.53 | Effectiveness of aromatase inhibitors in the treatment of advanced endometrial adenocarcinoma. ( Babilonti, L; Bogliolo, S; Cassani, C; De Silvestri, A; Dominoni, M; Gaggero, CR; Gardella, B; Musacchi, V; Spinillo, A; Zanellini, F, 2016) |
"The only alternative to breast cancer screening available in France is surgical prevention by prophylactic mastectomy." | 2.53 | [Hormonotherapy for breast cancer prevention: What about women with genetic predisposition to breast cancer?]. ( Callet, N; Fourme, E; Noguès, C; Reyal, F; Sénéchal, C; Stoppa-Lyonnet, D; This, P, 2016) |
"Fulvestrant is a new type of oestrogen receptor antagonist with no agonist effects." | 2.43 | Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents. ( Abram, P; Vergote, I, 2006) |
" This study provides RiBi-based markers relevant for a better selection of patients with advanced endometrial carcinoma by predicting the response of endocrine therapy combined with mTOR inhibitor." | 1.91 | Ribosome biogenesis-based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer: translational study from the VICTORIA trial in collaboration with the GINECO group. ( Abadie-Lacourtoisie, S; Bazan, F; Chabaud, S; Colombe-Vermorel, A; Coquan, E; Dalban, C; Diaz, JJ; Fabbro, M; Frenel, JS; Garin, G; Heudel, PE; Marcel, V; Martinez, S; Mourksi, NE; Odeyer, L; Pérol, D; Ray-Coquard, I; Simioni, V; Tabone-Eglinger, S; Treilleux, I, 2023) |
"Anastrozole was administered 1 mg daily orally after performing an accurate clinical and radiological staging." | 1.62 | Palliative treatment of endometrial cancer: what is the role of anastrozole in elderly women? ( Bogliolo, S; Carletti, GV; Cassani, C; De Silvestri, A; Dominoni, M; Gardella, B; Spinillo, A, 2021) |
"Low-grade endometrial stromal sarcoma is very rare and difficult to diagnose in the early stage." | 1.42 | Long-term survival in low-grade endometrial stromal sarcoma with childbirth and multidisciplinary treatment: a case report. ( Horio, M; Ichihara, S; Inoue, T; Ishihara, Y; Ito, M; Kondo, I; Maeda, O; Matsumura, Y; Moritani, S; Sugiyama, K; Yamamoto, S, 2015) |
"Anastrozole was effective to recurrent low-grade ESS even after being refractory to progestin therapy." | 1.37 | Aromatase inhibitor anastrozole as a second-line hormonal treatment to a recurrent low-grade endometrial stromal sarcoma: a case report. ( Ikeda, Y; Kawana, K; Kozuma, S; Nakagawa, S; Oda, K; Shoji, K; Takazawa, Y; Taketani, Y; Yasugi, T, 2011) |
"We compared the efficacy of endometrial cancer neoadjuvant treatment in 38 patients receiving nonsteroid (letrozol, anastrozol) or steroid (ekzemestan) aromatase inhibitors and 12 patients receiving metformin." | 1.37 | [Effectiveness of aromatase inhibitors in comparison with metformin for neoadjuvant treatment in patients with endometrial cancer]. ( Bershteĭn, LM; Boiarkina, MP; Danilova, MA; Gershfel'd, ÉD; Khadzhimba, AS; Kovalevskiĭ, AIu; Maksimov, SIa; Meshkova, IE; Turkevich, EA, 2011) |
"Patients with metastatic endometrial carcinoma may respond to hormonal therapy with progestins." | 1.33 | Durable response of metastatic endometrial carcinoma to treatment with fulvestrant (Faslodex) after prior progestin and anastrozole therapy. ( Hoffman, MA; Khan, A, 2006) |
"This is the first report of breast carcinoma metastatic to the endometrium in a patient on adjuvant anastrozole therapy." | 1.33 | Lobular carcinoma of the breast metastatic to the uterus in a patient under adjuvant anastrozole therapy. ( Bolat, F; Erkanli, S; Haberal, A; Kayaselcuk, F; Kuscu, E; Sakalli, H, 2006) |
"Hormonal therapy for endometrial cancer is occasionally warranted in the premenopausal woman who is interested in maintaining fertility." | 1.32 | Anastrozole, an aromatase inhibitor, and medroxyprogesterone acetate therapy in premenopausal obese women with endometrial cancer: a report of two cases successfully treated without hysterectomy. ( Amezcua, C; Bahador, A; Burnett, AF, 2004) |
"Letrozole was found to be a highly potent inhibitor of tumor proliferation and more effective than tamoxifen." | 1.30 | Preclinical studies using the intratumoral aromatase model for postmenopausal breast cancer. ( Brodie, A; Liu, Y; Long, B; Lu, Q; Wang, JP; Yue, W, 1998) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (3.57) | 18.2507 |
2000's | 12 (42.86) | 29.6817 |
2010's | 10 (35.71) | 24.3611 |
2020's | 5 (17.86) | 2.80 |
Authors | Studies |
---|---|
Heudel, P | 1 |
Frenel, JS | 2 |
Dalban, C | 2 |
Bazan, F | 2 |
Joly, F | 1 |
Arnaud, A | 1 |
Abdeddaim, C | 1 |
Chevalier-Place, A | 1 |
Augereau, P | 1 |
Pautier, P | 1 |
Chakiba, C | 1 |
You, B | 1 |
Lancry-Lecomte, L | 1 |
Garin, G | 2 |
Marcel, V | 2 |
Diaz, JJ | 2 |
Treilleux, I | 2 |
Pérol, D | 2 |
Fabbro, M | 2 |
Ray-Coquard, I | 2 |
Mourksi, NE | 1 |
Colombe-Vermorel, A | 1 |
Odeyer, L | 1 |
Simioni, V | 1 |
Abadie-Lacourtoisie, S | 1 |
Coquan, E | 1 |
Martinez, S | 1 |
Tabone-Eglinger, S | 1 |
Chabaud, S | 1 |
Heudel, PE | 1 |
Gardella, B | 2 |
Dominoni, M | 2 |
Bogliolo, S | 2 |
Cassani, C | 2 |
Carletti, GV | 1 |
De Silvestri, A | 2 |
Spinillo, A | 2 |
Friedlander, M | 2 |
Benson, C | 1 |
O'Connell, RL | 2 |
Reed, N | 1 |
Clamp, A | 2 |
Lord, R | 2 |
Millan, D | 2 |
Nottley, S | 2 |
Amant, F | 2 |
Steer, C | 1 |
Anand, A | 1 |
Mileshkin, L | 2 |
Beale, P | 2 |
Banerjee, S | 1 |
Bradshaw, N | 1 |
Kelly, C | 1 |
Carty, K | 2 |
Divers, L | 1 |
Alexander, L | 2 |
Edmondson, R | 2 |
Yanase, T | 1 |
Kikuchi, A | 1 |
Sasagawa, M | 1 |
Honma, S | 1 |
Sjoquist, KM | 1 |
Andrews, J | 1 |
Jyothirmayi, R | 1 |
Bonaventura, T | 1 |
Goh, J | 1 |
Hall, M | 1 |
Green, J | 1 |
Paul, J | 1 |
Scurry, J | 1 |
Boccardo, F | 1 |
Guglielmini, P | 1 |
Bordonaro, R | 1 |
Fini, A | 1 |
Massidda, B | 1 |
Porpiglia, M | 1 |
Roagna, R | 1 |
Serra, P | 1 |
Orzalesi, L | 1 |
Ucci, G | 1 |
Rubagotti, A | 1 |
Thangavelu, A | 1 |
Hewitt, MJ | 1 |
Quinton, ND | 1 |
Duffy, SR | 1 |
Maeda, O | 1 |
Moritani, S | 1 |
Ichihara, S | 1 |
Inoue, T | 1 |
Ishihara, Y | 1 |
Yamamoto, S | 1 |
Ito, M | 1 |
Matsumura, Y | 1 |
Sugiyama, K | 1 |
Horio, M | 1 |
Kondo, I | 1 |
Musacchi, V | 1 |
Zanellini, F | 1 |
Gaggero, CR | 1 |
Babilonti, L | 1 |
Sénéchal, C | 1 |
Reyal, F | 1 |
Callet, N | 1 |
This, P | 1 |
Noguès, C | 1 |
Stoppa-Lyonnet, D | 1 |
Fourme, E | 1 |
Bellone, S | 1 |
Shah, HR | 1 |
McKenney, JK | 1 |
Stone, PJ | 1 |
Santin, AD | 1 |
Barker, LC | 1 |
Brand, IR | 1 |
Crawford, SM | 1 |
Bershteĭn, LM | 2 |
Danilova, MA | 2 |
Kovalevskiĭ, AIu | 2 |
Gershfel'd, ED | 2 |
Poroshina, TE | 1 |
Tsyrlina, TE | 1 |
Meshkova, IE | 2 |
Turkevich, EA | 2 |
Maksimov, SIa | 2 |
Shoji, K | 1 |
Oda, K | 1 |
Nakagawa, S | 1 |
Kawana, K | 1 |
Yasugi, T | 1 |
Ikeda, Y | 1 |
Takazawa, Y | 1 |
Kozuma, S | 1 |
Taketani, Y | 1 |
Lisianskaia, AS | 1 |
Manikhas, GM | 1 |
Fadeeva, EP | 1 |
Fedosenko, KV | 1 |
Tapil'skaia, NI | 1 |
Boiarkina, MP | 1 |
Khadzhimba, AS | 1 |
Leiser, AL | 1 |
Hamid, AM | 1 |
Blanchard, R | 1 |
Burnett, AF | 1 |
Bahador, A | 1 |
Amezcua, C | 1 |
Hiura, M | 1 |
Oshita, T | 1 |
Nogawa, T | 1 |
Yokoyama, T | 1 |
Duffy, S | 1 |
Jackson, TL | 1 |
Lansdown, M | 1 |
Philips, K | 1 |
Wells, M | 1 |
Pollard, S | 1 |
Clack, G | 1 |
Coibion, M | 1 |
Bianco, AR | 1 |
Vergote, I | 1 |
Abram, P | 1 |
Hoffman, MA | 1 |
Khan, A | 1 |
Erkanli, S | 1 |
Kayaselcuk, F | 1 |
Kuscu, E | 1 |
Bolat, F | 1 |
Sakalli, H | 1 |
Haberal, A | 1 |
Alkasi, O | 1 |
Meinhold-Heerlein, I | 1 |
Zaki, R | 1 |
Fasching, P | 1 |
Maass, N | 1 |
Jonat, W | 1 |
Beckmann, MW | 1 |
Brodie, A | 1 |
Lu, Q | 1 |
Liu, Y | 1 |
Long, B | 1 |
Wang, JP | 1 |
Yue, W | 1 |
Rose, PG | 1 |
Brunetto, VL | 1 |
VanLe, L | 1 |
Bell, J | 1 |
Walker, JL | 1 |
Lee, RB | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Multicentric, Randomized, Non Comparative, Open-label Phase I/II Evaluating AZD2014 (Dual Mammalian Target of Rapamycin Complex 1/2 (mTORC1/mTORC2) Inhibitor) in Combination With Anastrozole Versus Anastrozole Alone in the Treatment of Metastatic Hormon[NCT02730923] | Phase 1/Phase 2 | 72 participants (Anticipated) | Interventional | 2016-04-30 | Active, not recruiting | ||
Gonadotropin-releasing Hormone Agonist Combined With Letrozole Compared With Megestrol Acetate or Medroxyprogesterone Acetate Alone as Fertility-sparing Treatment in Early Endometrial Cancer[NCT05247268] | Phase 2 | 104 participants (Anticipated) | Interventional | 2022-03-11 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 reviews available for anastrozole and Cancer of Endometrium
Article | Year |
---|---|
Effectiveness of aromatase inhibitors in the treatment of advanced endometrial adenocarcinoma.
Topics: Adenocarcinoma; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Endometria | 2016 |
[Hormonotherapy for breast cancer prevention: What about women with genetic predisposition to breast cancer?].
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Endometrial Neoplasms; Female; | 2016 |
[Postoperative hormone (endocrine) therapy in endometrial carcinoma].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Chemotherapy, Adjuvant; Drug The | 2004 |
Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms | 2006 |
7 trials available for anastrozole and Cancer of Endometrium
Article | Year |
---|---|
Safety and Efficacy of the mTOR Inhibitor, Vistusertib, Combined With Anastrozole in Patients With Hormone Receptor-Positive Recurrent or Metastatic Endometrial Cancer: The VICTORIA Multicenter, Open-label, Phase 1/2 Randomized Clinical Trial.
Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Breast Neoplasms; End | 2022 |
Phase 2 study of anastrozole in patients with estrogen receptor/progesterone receptor positive recurrent low-grade endometrial stromal sarcomas: The PARAGON trial (ANZGOG 0903).
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Endometrial Neoplasms; End | 2021 |
Phase 2 study of anastrozole in recurrent estrogen (ER)/progesterone (PR) positive endometrial cancer: The PARAGON trial - ANZGOG 0903.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Endometrial Neoplasms; Female; Humans; Immunohistochemi | 2019 |
Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: long term results of the Italian Tamoxifen Anastrozole trial.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; | 2013 |
Neoadjuvant treatment of endometrial cancer using anastrozole: a randomised pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; | 2013 |
The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) adjuvant breast cancer trial: first results of the endometrial sub-protocol following 2 years of treatment.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvan | 2006 |
A phase II trial of anastrozole in advanced recurrent or persistent endometrial carcinoma: a Gynecologic Oncology Group study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Carcino | 2000 |
17 other studies available for anastrozole and Cancer of Endometrium
Article | Year |
---|---|
Combination Vistusertib and Anastrozole Shows Benefit in Endometrial Cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Benzamides; Breast Neoplasms; Endometrial Neoplasms; F | 2022 |
Ribosome biogenesis-based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer: translational study from the VICTORIA trial in collaboration with the GINECO group.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Breast Neoplasms; En | 2023 |
Palliative treatment of endometrial cancer: what is the role of anastrozole in elderly women?
Topics: Aged; Aged, 80 and over; Anastrozole; Endometrial Neoplasms; Female; Humans; Nitriles; Palliative Ca | 2021 |
Two cases of endometrial cancer arising from adenomyosis during aromatase inhibitors therapy after mastectomy.
Topics: Adenocarcinoma; Adenomyosis; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Endometrial Neopla | 2017 |
Long-term survival in low-grade endometrial stromal sarcoma with childbirth and multidisciplinary treatment: a case report.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Endometrial Neoplasms; Female; Humans; | 2015 |
Recurrent endometrial carcinoma regression with the use of the aromatase inhibitor anastrozole.
Topics: Adenocarcinoma; Anastrozole; Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Immunohist | 2008 |
Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma.
Topics: Aged; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Carcinoma; Disease Progression; Endo | 2009 |
[Criteria for evaluating the effectiveness of aromatase inhibitors in the neoadjuvant treatment of patients with endometrial carcinoma].
Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Bi | 2009 |
Aromatase inhibitor anastrozole as a second-line hormonal treatment to a recurrent low-grade endometrial stromal sarcoma: a case report.
Topics: Adult; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; En | 2011 |
[Endometrial stromal sarcoma: complete response to therapy with aromatase-inhibitor, anastrozole].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Endometrial Neoplasms; Fem | 2010 |
[Effectiveness of aromatase inhibitors in comparison with metformin for neoadjuvant treatment in patients with endometrial cancer].
Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Ar | 2011 |
Recurrence of prolactin-producing endometrial stromal sarcoma with sex-cord stromal component treated with progestin and aromatase inhibitor.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromat | 2004 |
Anastrozole, an aromatase inhibitor, and medroxyprogesterone acetate therapy in premenopausal obese women with endometrial cancer: a report of two cases successfully treated without hysterectomy.
Topics: Adult; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Endometria | 2004 |
Durable response of metastatic endometrial carcinoma to treatment with fulvestrant (Faslodex) after prior progestin and anastrozole therapy.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Endometrial Neoplasms; Estradiol; Female; Fulves | 2006 |
Lobular carcinoma of the breast metastatic to the uterus in a patient under adjuvant anastrozole therapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Duc | 2006 |
Long-term disease-free survival after hormonal therapy of a patient with recurrent low grade endometrial stromal sarcoma: a case report.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Disease-Free Surviva | 2009 |
Preclinical studies using the intratumoral aromatase model for postmenopausal breast cancer.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocol | 1998 |