Page last updated: 2024-10-22

anastrozole and Atypical Endometrial Hyperplasia

anastrozole has been researched along with Atypical Endometrial Hyperplasia in 4 studies

Atypical Endometrial Hyperplasia: A benign form of endometrial hyperplasia with increased number of cells with atypia. The atypical cells are large and irregular and have an increased nuclear/cytoplasmic ratio. The risk of progression to endometrial carcinoma rises with the increasing degree of cell atypia.

Research Excerpts

ExcerptRelevanceReference
"This is a preliminary study investigating the efficacy of aromatase inhibitor anastrozole in treating endometrial hyperplasia in obese postmenopausal women."9.11Aromatase inhibitor anastrozole for treating endometrial hyperplasia in obese postmenopausal women. ( Agorastos, T; Bontis, JN; Efstathiadis, E; Pantazis, K; Vaitsi, V; Vavilis, D, 2005)
"To investigate whether there may be a role for aromatase inhibitors (AIs) in the treatment of endometrial hyperplasia (EH) and endometrial adenocarcinoma (EA) in postmenopausal women, a retrospective study on the effect of aromatase inhibitors (anastrozole or letrozole) was conducted for 16 patients who were not amenable to surgical treatment."7.75Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma. ( Barker, LC; Brand, IR; Crawford, SM, 2009)
"Adjuvant therapy with anastrozole may be beneficial in resolving endometrial hyperplasia in patients with breast cancer."7.74Resolution of endometrial hyperplasia with adjuvant anastrozole treatment in postmenopausal breast cancer: a case report. ( Cooper, BC; Stilwill, SE, 2007)
"This is a preliminary study investigating the efficacy of aromatase inhibitor anastrozole in treating endometrial hyperplasia in obese postmenopausal women."5.11Aromatase inhibitor anastrozole for treating endometrial hyperplasia in obese postmenopausal women. ( Agorastos, T; Bontis, JN; Efstathiadis, E; Pantazis, K; Vaitsi, V; Vavilis, D, 2005)
"To investigate whether there may be a role for aromatase inhibitors (AIs) in the treatment of endometrial hyperplasia (EH) and endometrial adenocarcinoma (EA) in postmenopausal women, a retrospective study on the effect of aromatase inhibitors (anastrozole or letrozole) was conducted for 16 patients who were not amenable to surgical treatment."3.75Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma. ( Barker, LC; Brand, IR; Crawford, SM, 2009)
"Adjuvant therapy with anastrozole may be beneficial in resolving endometrial hyperplasia in patients with breast cancer."3.74Resolution of endometrial hyperplasia with adjuvant anastrozole treatment in postmenopausal breast cancer: a case report. ( Cooper, BC; Stilwill, SE, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barker, LC1
Brand, IR1
Crawford, SM1
Koloszar, S1
Pal, Z1
Kereszturi, A1
Vajda, G1
Pal, A1
Daru, J1
Agorastos, T1
Vaitsi, V1
Pantazis, K1
Efstathiadis, E1
Vavilis, D1
Bontis, JN1
Stilwill, SE1
Cooper, BC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Gonadotropin-releasing Hormone Agonist Combined With Letrozole Compared With Megestrol Acetate or Medroxyprogesterone Acetate Alone as Fertility-sparing Treatment in Early Endometrial Cancer[NCT05247268]Phase 2104 participants (Anticipated)Interventional2022-03-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for anastrozole and Atypical Endometrial Hyperplasia

ArticleYear
Aromatase inhibitor anastrozole for treating endometrial hyperplasia in obese postmenopausal women.
    European journal of obstetrics, gynecology, and reproductive biology, 2005, Feb-01, Volume: 118, Issue:2

    Topics: Aged; Anastrozole; Aromatase Inhibitors; Body Mass Index; Endometrial Hyperplasia; Endometrium; Fema

2005

Other Studies

3 other studies available for anastrozole and Atypical Endometrial Hyperplasia

ArticleYear
Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma.
    Current medical research and opinion, 2009, Volume: 25, Issue:5

    Topics: Aged; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Carcinoma; Disease Progression; Endo

2009
Effects of aromatase inhibitor on menopausal hyperplasia in a case of obesity.
    Climacteric : the journal of the International Menopause Society, 2012, Volume: 15, Issue:1

    Topics: Administration, Oral; Aged; Anastrozole; Aromatase Inhibitors; Atrophy; Endometrial Hyperplasia; End

2012
Resolution of endometrial hyperplasia with adjuvant anastrozole treatment in postmenopausal breast cancer: a case report.
    The Journal of reproductive medicine, 2007, Volume: 52, Issue:10

    Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Endometrial Hyperplasia

2007