Page last updated: 2024-10-22

anastrozole and Arthralgia

anastrozole has been researched along with Arthralgia in 26 studies

Arthralgia: Pain in the joint.

Research Excerpts

ExcerptRelevanceReference
"Purpose The Letrozole (Femara) Versus Anastrozole Clinical Evaluation (FACE) study compared the efficacy and safety of adjuvant letrozole versus anastrozole in postmenopausal patients with hormone receptor (HR) -positive and node-positive early breast cancer (eBC)."9.24Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor-Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evaluation ( Amadori, D; Burris, H; Comarella, L; De Boer, R; Dowsett, M; Ejlertsen, B; Gnant, M; Hart, L; Jonat, W; McIntyre, K; O'Shaughnessy, J; Poggio, S; Pritchard, KI; Salomon, H; Smith, I; Wamil, B; Yardley, D, 2017)
"This prospective study evaluated the relationship between arthralgia and compliance during the first year of adjuvant anastrozole therapy in postmenopausal women with hormone receptor-positive early breast cancer."9.19COMPliance and Arthralgia in Clinical Therapy: the COMPACT trial, assessing the incidence of arthralgia, and compliance within the first year of adjuvant anastrozole therapy. ( Blettner, M; Bolten, W; Hadji, P; Harbeck, N; Hindenburg, HJ; Jackisch, C; Klein, P; König, K; Kreienberg, R; Rief, W; Wallwiener, D; Zaun, S, 2014)
"The addition of oral risedronate in post-menopausal breast cancer patients receiving anastrozole has a favorable effect on BMD."9.14Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial. ( Antonopoulou, Z; Dafni, U; Gogas, H; Kalogerakos, K; Koukouras, D; Lazarou, S; Markopoulos, C; Misitzis, J; Papadiamantis, J; Polychronis, A; Sarantopoulou, A; Siasos, N; Tzoracoleftherakis, E; Venizelos, B; Xepapadakis, G; Zobolas, V, 2010)
"Our results suggested that BMI and AI drug (letrozole versus anastrozole) were clinical predictors of arthralgia, while genetic variants rs4775936, rs9322336, rs2234693, and rs9340799 were genetic predictors of AI-induced arthralgia."7.96Genetic and clinical predictors of arthralgia during letrozole or anastrozole therapy in breast cancer patients. ( Borrie, AE; Choi, YH; Hahn, K; Kim, RB; Lenehan, J; Lock, M; Logan, D; Perera, FE; Potvin, K; Read, N; Rose, FA; Sexton, T; Teft, WA; Vandenberg, TA; Welch, S; Yaremko, B; Younus, J; Yu, E, 2020)
"Anastrozole, an aromatase inhibitor widely used in breast cancer, has recently been indicated to be a P-glycoprotein (ABCB1) substrate."7.85Polymorphisms in ABCB1 and CYP19A1 genes affect anastrozole plasma concentrations and clinical outcomes in postmenopausal breast cancer patients. ( Carrillo, JA; Gervasini, G; Jara, C; Martínez, R; Olier, C; Romero, N, 2017)
"Although anastrozole (ANA), an aromatase inhibitor (AI), has been widely used for breast cancer patients; adverse events during ANA therapy in Japanese patients have not been reported."7.76Adverse events and bone health during anastrozole therapy in postmenopausal Japanese breast cancer patients. ( Ando, M; Baba, S; Dokiya, F; Douchi, T; Kosha, S; Matsuyama, Y; Ohi, Y; Rai, Y; Sagara, Y; Tamada, S, 2010)
"More than a third of breast cancer patients undergoing aromatase inhibitor (AI) treatment report joint pain."5.39Anastrozole-associated joint pain and other symptoms in patients with breast cancer. ( Cleeland, CS; Giordano, SH; Lu, H; Malveaux, D; Saleeba, AK; Shi, Q, 2013)
"Purpose The Letrozole (Femara) Versus Anastrozole Clinical Evaluation (FACE) study compared the efficacy and safety of adjuvant letrozole versus anastrozole in postmenopausal patients with hormone receptor (HR) -positive and node-positive early breast cancer (eBC)."5.24Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor-Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evaluation ( Amadori, D; Burris, H; Comarella, L; De Boer, R; Dowsett, M; Ejlertsen, B; Gnant, M; Hart, L; Jonat, W; McIntyre, K; O'Shaughnessy, J; Poggio, S; Pritchard, KI; Salomon, H; Smith, I; Wamil, B; Yardley, D, 2017)
"This prospective study evaluated the relationship between arthralgia and compliance during the first year of adjuvant anastrozole therapy in postmenopausal women with hormone receptor-positive early breast cancer."5.19COMPliance and Arthralgia in Clinical Therapy: the COMPACT trial, assessing the incidence of arthralgia, and compliance within the first year of adjuvant anastrozole therapy. ( Blettner, M; Bolten, W; Hadji, P; Harbeck, N; Hindenburg, HJ; Jackisch, C; Klein, P; König, K; Kreienberg, R; Rief, W; Wallwiener, D; Zaun, S, 2014)
"The addition of oral risedronate in post-menopausal breast cancer patients receiving anastrozole has a favorable effect on BMD."5.14Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial. ( Antonopoulou, Z; Dafni, U; Gogas, H; Kalogerakos, K; Koukouras, D; Lazarou, S; Markopoulos, C; Misitzis, J; Papadiamantis, J; Polychronis, A; Sarantopoulou, A; Siasos, N; Tzoracoleftherakis, E; Venizelos, B; Xepapadakis, G; Zobolas, V, 2010)
"Our results suggested that BMI and AI drug (letrozole versus anastrozole) were clinical predictors of arthralgia, while genetic variants rs4775936, rs9322336, rs2234693, and rs9340799 were genetic predictors of AI-induced arthralgia."3.96Genetic and clinical predictors of arthralgia during letrozole or anastrozole therapy in breast cancer patients. ( Borrie, AE; Choi, YH; Hahn, K; Kim, RB; Lenehan, J; Lock, M; Logan, D; Perera, FE; Potvin, K; Read, N; Rose, FA; Sexton, T; Teft, WA; Vandenberg, TA; Welch, S; Yaremko, B; Younus, J; Yu, E, 2020)
"Anastrozole, an aromatase inhibitor widely used in breast cancer, has recently been indicated to be a P-glycoprotein (ABCB1) substrate."3.85Polymorphisms in ABCB1 and CYP19A1 genes affect anastrozole plasma concentrations and clinical outcomes in postmenopausal breast cancer patients. ( Carrillo, JA; Gervasini, G; Jara, C; Martínez, R; Olier, C; Romero, N, 2017)
"Postmenopausal women with an early breast cancer scheduled to start adjuvant endocrine therapy with an AI or tamoxifen were recruited."3.80Arthralgia induced by endocrine treatment for breast cancer: A prospective study of serum levels of insulin like growth factor-I, its binding protein and oestrogens. ( Billen, J; Christiaens, MR; Jans, I; Laenen, A; Lintermans, A; Neven, P; Paridaens, R; Pauwels, S; Van Asten, K; Van Herck, E; Vanderschueren, D; Verhaeghe, J; Vermeersch, P; Wildiers, H, 2014)
"We conducted a prospective study including postmenopausal early breast cancer patients receiving either an aromatase inhibitor (AI) or tamoxifen."3.77Aromatase inhibitor-induced loss of grip strength is body mass index dependent: hypothesis-generating findings for its pathogenesis. ( Christiaens, MR; De Smet, L; Dieudonné, AS; Henry, NL; Leunen, K; Lintermans, A; Morales, L; Neven, P; Pans, S; Paridaens, R; Timmerman, D; Van Calster, B; Van Hoydonck, M; Vergote, I; Verhaeghe, J; Verschueren, K; Westhovens, R; Wildiers, H, 2011)
" Because her arthralgia showed no improvement, powdered processed aconitine root was added."3.77A case of aromatase inhibitor (anastrozole)-induced side-effects successfully treated with Kampo medicines. ( Chino, A; Hirasaki, Y; Namiki, T; Ogawa, K; Okamoto, H; Ueda, K, 2011)
"Although anastrozole (ANA), an aromatase inhibitor (AI), has been widely used for breast cancer patients; adverse events during ANA therapy in Japanese patients have not been reported."3.76Adverse events and bone health during anastrozole therapy in postmenopausal Japanese breast cancer patients. ( Ando, M; Baba, S; Dokiya, F; Douchi, T; Kosha, S; Matsuyama, Y; Ohi, Y; Rai, Y; Sagara, Y; Tamada, S, 2010)
" The aim of this study was to assess the relative importance of different risk factors for treatment-emergent joint symptoms in patients assigned to anastrozole or tamoxifen as adjuvant treatment for postmenopausal breast cancer."3.74Risk factors for joint symptoms in patients enrolled in the ATAC trial: a retrospective, exploratory analysis. ( Bianco, AR; Buzdar, AU; Cuzick, J; Eastell, R; Forbes, JF; Sapunar, F; Sestak, I, 2008)
"Women with hormone-receptor-positive tumours who reported vasomotor or joint symptoms at the first follow-up visit (3 months) in the ATAC trial, (which assessed tamoxifen or anastrozole for adjuvant treatment of postmenopausal breast cancer), were compared with women without these symptoms to see if there was a relation between these symptoms and subsequent recurrence."3.74Treatment-emergent endocrine symptoms and the risk of breast cancer recurrence: a retrospective analysis of the ATAC trial. ( Cella, D; Cuzick, J; Fallowfield, L; Sestak, I, 2008)
"More than a third of breast cancer patients undergoing aromatase inhibitor (AI) treatment report joint pain."1.39Anastrozole-associated joint pain and other symptoms in patients with breast cancer. ( Cleeland, CS; Giordano, SH; Lu, H; Malveaux, D; Saleeba, AK; Shi, Q, 2013)
"Arthralgias have been frequently cited as the primary reason for discontinuation of AI therapy."1.38Incidence and management of arthralgias in breast cancer patients treated with aromatase inhibitors in an outpatient oncology clinic. ( Carro, G; Harper, A; Hui, W; Lawton, J; Menas, P; Merkel, D, 2012)
"With these treatments, joint pain is frequent (30% to 40%) and quite often disabling (5% to 10%)."1.34Joint pain with aromatase inhibitors: abnormal frequency of Sjögren's syndrome. ( Borg, S; De Lafontan, B; Laroche, M; Lassoued, S; Roché, H, 2007)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (23.08)29.6817
2010's18 (69.23)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Luo, B1
Kong, L1
Yuan, M1
Borrie, AE1
Rose, FA1
Choi, YH1
Perera, FE1
Read, N1
Sexton, T1
Lock, M1
Vandenberg, TA1
Hahn, K1
Younus, J1
Logan, D1
Potvin, K1
Yaremko, B1
Yu, E1
Lenehan, J1
Welch, S1
Teft, WA1
Kim, RB1
Niravath, P1
Chen, B1
Chapman, JW1
Agarwal, SK1
Welschhans, RL1
Bongartz, T1
Kalari, KR1
Shepherd, LE1
Bartlett, J1
Pritchard, K1
Gelmon, K1
Hilsenbeck, SG1
Rimawi, MF1
Osborne, CK1
Goss, PE1
Ingle, JN1
Shi, Q1
Giordano, SH1
Lu, H1
Saleeba, AK1
Malveaux, D1
Cleeland, CS1
Hadji, P1
Jackisch, C1
Bolten, W1
Blettner, M1
Hindenburg, HJ1
Klein, P1
König, K1
Kreienberg, R1
Rief, W1
Wallwiener, D1
Zaun, S1
Harbeck, N1
Mao, JJ1
Farrar, JT1
Bruner, D1
Zee, J1
Bowman, M1
Seluzicki, C1
DeMichele, A1
Xie, SX1
Lintermans, A2
Vanderschueren, D1
Verhaeghe, J2
Van Asten, K1
Jans, I1
Van Herck, E1
Laenen, A1
Paridaens, R2
Billen, J1
Pauwels, S1
Vermeersch, P1
Wildiers, H2
Christiaens, MR2
Neven, P2
Marchand, A1
Georgin-Mège, M1
Cellier, P1
Martin, L1
Avenel-Audran, M1
Le Corre, Y1
Shapiro, AC1
Adlis, SA1
Robien, K1
Kirstein, MN1
Liang, S1
Richter, SA1
Lerner, RE1
Gervasini, G1
Jara, C1
Olier, C1
Romero, N1
Martínez, R1
Carrillo, JA1
Smith, I1
Yardley, D1
Burris, H1
De Boer, R1
Amadori, D1
McIntyre, K1
Ejlertsen, B1
Gnant, M1
Jonat, W1
Pritchard, KI1
Dowsett, M1
Hart, L1
Poggio, S1
Comarella, L1
Salomon, H1
Wamil, B1
O'Shaughnessy, J1
Sestak, I2
Cuzick, J3
Sapunar, F1
Eastell, R1
Forbes, JF1
Bianco, AR1
Buzdar, AU1
Cella, D1
Fallowfield, L1
Sagara, Y3
Kosha, S1
Baba, S1
Dokiya, F1
Tamada, S1
Matsuyama, Y1
Ohi, Y1
Ando, M1
Rai, Y1
Douchi, T1
Markopoulos, C1
Tzoracoleftherakis, E1
Polychronis, A1
Venizelos, B1
Dafni, U1
Xepapadakis, G1
Papadiamantis, J1
Zobolas, V1
Misitzis, J1
Kalogerakos, K1
Sarantopoulou, A1
Siasos, N1
Koukouras, D1
Antonopoulou, Z1
Lazarou, S1
Gogas, H1
Van Calster, B1
Van Hoydonck, M1
Pans, S1
Westhovens, R1
Henry, NL1
Dieudonné, AS1
Leunen, K1
Morales, L1
Verschueren, K1
Timmerman, D1
De Smet, L1
Vergote, I1
Nagykálnai, T1
Landherr, L1
Mészáros, E1
Kanematsu, M1
Morimoto, M1
Honda, J1
Nagao, T1
Nakagawa, M1
Takahashi, M1
Tangoku, A1
Sasa, M1
Chino, A1
Okamoto, H1
Hirasaki, Y1
Ueda, K1
Ogawa, K1
Namiki, T1
Singh, S1
Mesher, D1
Richmond, B1
Howell, A1
Menas, P1
Merkel, D1
Hui, W1
Lawton, J1
Harper, A1
Carro, G1
Kubo, M1
Onishi, H1
Kuroki, S1
Okido, M1
Shimada, K1
Yokohata, K1
Umeda, S1
Ogawa, T1
Tanaka, M1
Katano, M1
Altundag, K1
Dede, D1
Harputluoglu, H1
Gullu, I1
Laroche, M1
Borg, S1
Lassoued, S1
De Lafontan, B1
Roché, H1
Wengström, Y1
Donnellan, PP1
Douglas, SL1
Cameron, DA1
Leonard, RC1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Arimidex: Compliance and Arthralgias in Clinical Therapy (COMPACT): An in Practice Assessment of Arthralgias and Related Costs as Well as Compliance in the First Year of Anastrozole Therapy[NCT00857012]2,313 participants (Actual)Observational2009-04-30Completed
Phase 2 Study Vitamin D3 Effects on Musculoskeletal Symptoms With Use of Aromatase Inhibitors[NCT01509079]Phase 2116 participants (Actual)Interventional2012-03-31Completed
A Randomised Effectiveness-implementation Trial for Evaluating Dietary and Manual Treatment With Osteopathic Techniques on Quality of Life and on Modulation of the Inflammatory State of Patients Diagnosed With Breast Cancer Undergoing Antiestrogenic Hormo[NCT06164119]600 participants (Anticipated)Interventional2023-12-31Not yet recruiting
A Phase III-IV, Multicenter Open Label Trial of Arimidex Alone Versus Arimidex Plus Bisphosphonates in Postmenopausal Patients With Early, Endocrine Positive Breast Cancer.[NCT00809484]220 participants (Actual)Observational2004-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Average Percent Adherence to Vitamin D Interventio

adherence measured with pill counts for the vitamin D at predesignated study timepoints: baseline (after run-in), 3 months and 6 months (NCT01509079)
Timeframe: average for all study ppts for: screening to baseline; baseline to 3 months; 3 month to 6 months

Intervention% of adherence for each treatment arm (Number)
Vitamin D3 4000 IU95
Vitamin D3 600 IU95

Change in Hand Grip Strength

(NCT01509079)
Timeframe: baseline to 6 months

Interventionpounds (Mean)
Vitamin D3 4000 IU1.8
Vitamin D3 600 IU1.0

Change in Musculoskeletal Symptom Sub-scale on the Breast Cancer Prevention Trial Symptom Scale

The MS subscale is a self-reported measure on a scale of 0 to 4, with lower score indicating less arthralgia/myalgia (NCT01509079)
Timeframe: baseline to 6 months

Interventionunits on a scale (Mean)
Vitamin D3 4000 IU-0.2
Vitamin D3 600 IU-0.5

Change in PROMIS Physical Functioning Questionnaire

PROMIS measures physical functioning on the short form and higher scores reflect better physical functioning with 10 questions on daily activities of life on a Likert scale ranging from 5 (no problem performing activity) to 1 (cannot do activity). Range on this measure is from 50 (best)-10 (worst). (NCT01509079)
Timeframe: baseline to 6 months

Interventionunits on a scale (Mean)
Vitamin D3 4000 IU0.6
Vitamin D3 600 IU1.7

Whole Body Bone Mineral Density

GLM Mean and standard deviation of Whole Body Bone Mineral Density (grams/cm2) of Trial Participants by Treatment Arm after controlling for bisphosphonate use (NCT01509079)
Timeframe: From Baseline and 6 months of D3 supplementation

Interventiongm/cm2 (Geometric Least Squares Mean)
Vitamin D3 4000 IU1.1
Vitamin D3 600 IU1.12

Change in Steady State Concentrations of Serum Anastrazole and Letrozole

Difference in steady state concentrations in plasma from baseline to 6 months (NCT01509079)
Timeframe: baseline to 6 months

,
Interventionmg/L (Mean)
anastrozoleletrozole
Vitamin D3 4000 IU-1.312.16
Vitamin D3 600 IU2.4-0.83

Serum Estradiol Concentrations

(NCT01509079)
Timeframe: baseline and 6 months

,
Interventionpg/ml (Geometric Mean)
Baseline6 months
Vitamin D3 4000 IU2.832.94
Vitamin D3 600 IU2.773.0

Reviews

2 reviews available for anastrozole and Arthralgia

ArticleYear
[Aromatase inhibitors and arthralgia].
    Magyar onkologia, 2011, Volume: 55, Issue:1

    Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Brea

2011
Effectively nursing patients receiving aromatase inhibitor therapy.
    Breast (Edinburgh, Scotland), 2008, Volume: 17, Issue:3

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromat

2008

Trials

8 trials available for anastrozole and Arthralgia

ArticleYear
Vitamin D Levels, Vitamin D Receptor Polymorphisms, and Inflammatory Cytokines in Aromatase Inhibitor-Induced Arthralgias: An Analysis of CCTG MA.27.
    Clinical breast cancer, 2018, Volume: 18, Issue:1

    Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Arthralgia; Breast Neopl

2018
COMPliance and Arthralgia in Clinical Therapy: the COMPACT trial, assessing the incidence of arthralgia, and compliance within the first year of adjuvant anastrozole therapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:2

    Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Breast Neoplasms; Chemotherapy, Adju

2014
Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia: a randomized trial.
    Cancer, 2014, Dec-01, Volume: 120, Issue:23

    Topics: Aged; Anastrozole; Androstadienes; Anxiety; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Depr

2014
Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS).
    Breast cancer research and treatment, 2016, Volume: 155, Issue:3

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Bone De

2016
Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor-Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evaluation
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, Apr-01, Volume: 35, Issue:10

    Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Breast Neoplasms; Chemotherapy, Adju

2017
Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial.
    Breast cancer research : BCR, 2010, Volume: 12, Issue:2

    Topics: Administration, Oral; Aged; Anastrozole; Aromatase Inhibitors; Arthralgia; Bone Density; Bone Densit

2010
Effect of baseline serum vitamin D levels on aromatase inhibitors induced musculoskeletal symptoms: results from the IBIS-II, chemoprevention study using anastrozole.
    Breast cancer research and treatment, 2012, Volume: 132, Issue:2

    Topics: Adult; Aged; Anastrozole; Anticarcinogenic Agents; Aromatase Inhibitors; Arthralgia; Biomarkers; Bre

2012
Short-term and low-dose prednisolone administration reduces aromatase inhibitor-induced arthralgia in patients with breast cancer.
    Anticancer research, 2012, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Anastrozole; Anti-Inflammatory Agents; Aromatase Inhibitors; Arthralgia; Br

2012

Other Studies

16 other studies available for anastrozole and Arthralgia

ArticleYear
An experience of the intervention effect of individualized on the rehabilitation exercise on bone and joint pain symptoms caused by anastrozole.
    Asian journal of surgery, 2023, Volume: 46, Issue:7

    Topics: Anastrozole; Arthralgia; Bone and Bones; Breast Neoplasms; Exercise Therapy; Female; Humans

2023
Genetic and clinical predictors of arthralgia during letrozole or anastrozole therapy in breast cancer patients.
    Breast cancer research and treatment, 2020, Volume: 183, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Aromatase; Aromatase Inhibitors; Arthralgia; Biomarkers

2020
Anastrozole-associated joint pain and other symptoms in patients with breast cancer.
    The journal of pain, 2013, Volume: 14, Issue:3

    Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Breast Neoplasms; Cohort Studies; Fe

2013
Arthralgia induced by endocrine treatment for breast cancer: A prospective study of serum levels of insulin like growth factor-I, its binding protein and oestrogens.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:17

    Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromat

2014
Exemestane-induced radiation recall dermatitis and morbilliform rash.
    The Journal of dermatology, 2016, Volume: 43, Issue:5

    Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Arthralgia; Carcinom

2016
Polymorphisms in ABCB1 and CYP19A1 genes affect anastrozole plasma concentrations and clinical outcomes in postmenopausal breast cancer patients.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:3

    Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Arthralgia; ATP Binding Cassette Transporter, Subfamil

2017
Risk factors for joint symptoms in patients enrolled in the ATAC trial: a retrospective, exploratory analysis.
    The Lancet. Oncology, 2008, Volume: 9, Issue:9

    Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols;

2008
Treatment-emergent endocrine symptoms and the risk of breast cancer recurrence: a retrospective analysis of the ATAC trial.
    The Lancet. Oncology, 2008, Volume: 9, Issue:12

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Biomarkers, Tumor; Breast Neo

2008
Adverse events and bone health during anastrozole therapy in postmenopausal Japanese breast cancer patients.
    Breast cancer (Tokyo, Japan), 2010, Volume: 17, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Arthralgia; Bone Density; Breast

2010
Aromatase inhibitor-induced loss of grip strength is body mass index dependent: hypothesis-generating findings for its pathogenesis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:8

    Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Arthralgia; Body Mass Index; Breast Neoplas

2011
The time since last menstrual period is important as a clinical predictor for non-steroidal aromatase inhibitor-related arthralgia.
    BMC cancer, 2011, Oct-10, Volume: 11

    Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Female;

2011
A case of aromatase inhibitor (anastrozole)-induced side-effects successfully treated with Kampo medicines.
    Journal of alternative and complementary medicine (New York, N.Y.), 2011, Volume: 17, Issue:11

    Topics: Aconitine; Aconitum; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia;

2011
Incidence and management of arthralgias in breast cancer patients treated with aromatase inhibitors in an outpatient oncology clinic.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2012, Volume: 18, Issue:4

    Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Female; Humans; Inc

2012
Aromatase inhibitor-associated arthralgias: Pathogenesis, frequency and management.
    Joint bone spine, 2007, Volume: 74, Issue:6

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Ch

2007
Joint pain with aromatase inhibitors: abnormal frequency of Sjögren's syndrome.
    The Journal of rheumatology, 2007, Volume: 34, Issue:11

    Topics: Aged; Anastrozole; Antibodies, Antinuclear; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; A

2007
Aromatase inhibitors and arthralgia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, May-15, Volume: 19, Issue:10

    Topics: Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Breast Neoplasms; Enzyme Inhibitors; Femal

2001