anacetrapib and Hyperlipidemias

anacetrapib has been researched along with Hyperlipidemias* in 1 studies

Other Studies

1 other study(ies) available for anacetrapib and Hyperlipidemias

Article	Year
Synthesis and biological evaluation of isoflavone amide derivatives with antihyperlipidemic and preadipocyte antiproliferative activities. Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15 A series of isoflavone amides were designed with isoflavone in place of the scaffold of 2-arylbenzoxazole as cholesterol ester transfer protein (CETP) inhibitors. Twelve new compounds were synthesized, and their inhibitory activities of CETP and preadipocyte proliferation were assayed. The hypolipidemic potency of the most effective compound HY-2c was further tested in vivo by hamster. The results indicate that HY-2c exhibited favorable antihyperlipidemic and preadipocyte antiproliferative activities. Topics: Acetanilides; Adipocytes; Amides; Animals; Cell Proliferation; Cholesterol Ester Transfer Proteins; Chromones; Cricetinae; Disease Models, Animal; Hyperlipidemias; Hypolipidemic Agents; Isoflavones; Male; Olive Oil	2015

Article

Year

Synthesis and biological evaluation of isoflavone amide derivatives with antihyperlipidemic and preadipocyte antiproliferative activities.

Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15

A series of isoflavone amides were designed with isoflavone in place of the scaffold of 2-arylbenzoxazole as cholesterol ester transfer protein (CETP) inhibitors. Twelve new compounds were synthesized, and their inhibitory activities of CETP and preadipocyte proliferation were assayed. The hypolipidemic potency of the most effective compound HY-2c was further tested in vivo by hamster. The results indicate that HY-2c exhibited favorable antihyperlipidemic and preadipocyte antiproliferative activities.

Topics: Acetanilides; Adipocytes; Amides; Animals; Cell Proliferation; Cholesterol Ester Transfer Proteins; Chromones; Cricetinae; Disease Models, Animal; Hyperlipidemias; Hypolipidemic Agents; Isoflavones; Male; Olive Oil

2015