amylopectin has been researched along with Pancreatic-Neoplasms* in 1 studies
1 other study(ies) available for amylopectin and Pancreatic-Neoplasms
| Article | Year |
|---|---|
Spectroscopic investigation of a hyperbranched cationic amylopectin derivative as a multi-guest molecular host for targeted delivery of a photosensitizer to pancreatic cancer cells.
To increase pancreatic tumor-targeted phototoxicity of photosensitizers, a hyperbranched cationic amylopectin derivative conjugated with 3-(dimethylamino)-1-propylamine (DMAPA-Amp) was invevstigated as a multi-guest molecular host for the targeted delivery of a photosensitizer to human pancreatic cancer (Panc-1) cells. We selected protoporphyrin IX (PpIX) and folic acid as a photosensitizer and a tumor-targeting factor, respectively. The complexation mechanism of DMAPA-Amp with PpIX and folic acid was characterized using NMR spectroscopy including Topics: Amylopectin; Cations; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Folic Acid; Humans; Magnetic Resonance Spectroscopy; Pancreatic Neoplasms; Photosensitizing Agents; Protoporphyrins; Spectrometry, Fluorescence; Spectrometry, X-Ray Emission; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 2018 |