amyloid-beta-peptides has been researched along with Vitamin-B-Deficiency* in 1 studies
1 trial(s) available for amyloid-beta-peptides and Vitamin-B-Deficiency
| Article | Year |
|---|---|
B-vitamins reduce plasma levels of beta amyloid.
Elevated plasma homocysteine (tHcy) is a risk factor for Alzheimer's disease (AD), and thus B vitamins may have a role in the prevention of AD. The objective of this study was to determine if tHcy lowering vitamins decrease the circulating levels of A-beta protein 1-40 (A beta 40). We randomized 299 older men to treatment with 2mg of folate, plus 25mg of B6 and 400 microg of B12, or placebo. After 2 years of treatment the mean (S.E.) increase of A beta 40 was 7.0 pg/ml (8.4) in the vitamin group (4.9%), and 26.8 pg/ml (7.7) (18.5%) in the placebo group. We conclude that B vitamins may decrease the plasma level of A beta 40 and have a role in the prevention of AD. Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Double-Blind Method; Homocysteine; Humans; Longitudinal Studies; Peptide Fragments; Vitamin B Complex; Vitamin B Deficiency | 2008 |