amyloid-beta-peptides and Polymyalgia-Rheumatica

amyloid-beta-peptides has been researched along with Polymyalgia-Rheumatica* in 1 studies

Trials

1 trial(s) available for amyloid-beta-peptides and Polymyalgia-Rheumatica

Article	Year
Prednisolone (30-60 mg/day) for diseases other than AD decreases amyloid beta-peptides in CSF. Neurology, 2002, May-14, Volume: 58, Issue:9 The effect of corticosteroid on the concentration of amyloid beta-peptide (Abeta) in human CSF obtained from 16 patients without dementia treated with prednisolone (> or =30 mg daily) was studied. The concentrations of Abetax-40 and Abetax-42 in CSF decreased after treatment was started (p < 0.002). A moderate- or high-dose regimen of prednisolone decreases Abeta production or increases Abeta degradation in the human brain and deserves further study in AD. Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amyloid beta-Peptides; Brain; Cranial Nerve Diseases; Dose-Response Relationship, Drug; Female; Glucocorticoids; Graves Disease; Humans; Male; Middle Aged; Multiple Sclerosis; Peptide Fragments; Polymyalgia Rheumatica; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Prednisolone	2002

Article

Year

Prednisolone (30-60 mg/day) for diseases other than AD decreases amyloid beta-peptides in CSF.

Neurology, 2002, May-14, Volume: 58, Issue:9

The effect of corticosteroid on the concentration of amyloid beta-peptide (Abeta) in human CSF obtained from 16 patients without dementia treated with prednisolone (> or =30 mg daily) was studied. The concentrations of Abetax-40 and Abetax-42 in CSF decreased after treatment was started (p < 0.002). A moderate- or high-dose regimen of prednisolone decreases Abeta production or increases Abeta degradation in the human brain and deserves further study in AD.

Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amyloid beta-Peptides; Brain; Cranial Nerve Diseases; Dose-Response Relationship, Drug; Female; Glucocorticoids; Graves Disease; Humans; Male; Middle Aged; Multiple Sclerosis; Peptide Fragments; Polymyalgia Rheumatica; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Prednisolone

2002