amyloid-beta-peptides has been researched along with Herpes-Zoster* in 2 studies
2 other study(ies) available for amyloid-beta-peptides and Herpes-Zoster
| Article | Year |
|---|---|
Cerebral spinal fluid biomarker profiles in CNS infection associated with HSV and VZV mimic patterns in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Central Nervous System Infections; Cerebrospinal Fluid; DNA, Viral; Herpes Simplex; Herpes Zoster; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Peptide Fragments; tau Proteins | 2021 |
Acute zoster plasma contains elevated amyloid, correlating with Aβ42 and amylin levels, and is amyloidogenic.
Herpes zoster is associated with an increased dementia and neovascular macular degeneration risk and a decline in glycemic control in diabetes mellitus. Because amyloid is present and pathogenic in these diseases, we quantified amyloid, Aβ40, Aβ42, and amylin in 14 zoster and 10 control plasmas. Compared with controls, zoster plasma had significantly elevated amyloid that correlated with Aβ42 and amylin levels and increased amyloid aggregation with addition of exogenous Aβ42 or amylin. These results suggest that zoster plasma contains factor(s) that promotes aggregation of amyloidogenic peptides, potentially contributing to the toxic amyloid burden and explaining accelerated disease progression following zoster. Topics: Adult; Aged; Aged, 80 and over; Amyloid beta-Peptides; Case-Control Studies; Female; Gene Expression; Herpes Zoster; Herpesvirus 3, Human; Host-Pathogen Interactions; Humans; Islet Amyloid Polypeptide; Male; Middle Aged; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological | 2020 |