amsacrine has been researched along with Vomiting in 7 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
Excerpt | Relevance | Reference |
---|---|---|
"Leukopenia was found to be dose-limiting; thrombocytopenia and anemia were also observed." | 1.26 | Phase II study of m-AMSA in advances malignant melanoma. ( Arseneau, JC; Kuperminc, M; Probert, JC; Wolter, JM, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (85.71) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hines, JD | 1 |
Oken, MM | 1 |
Mazza, JJ | 1 |
Keller, AM | 1 |
Streeter, RR | 1 |
Glick, JH | 1 |
Arlin, ZA | 1 |
Dombernowsky, P | 1 |
Siegenthaler, P | 1 |
Somers, R | 1 |
Hansen, HH | 1 |
Arseneau, JC | 1 |
Wolter, JM | 1 |
Probert, JC | 1 |
Kuperminc, M | 1 |
Issell, BF | 1 |
Sundström, GM | 1 |
Wahlin, A | 1 |
Willemze, R | 1 |
Peters, WG | 1 |
van Hennik, MB | 1 |
Fibbe, WE | 1 |
Kootte, AM | 1 |
van Berkel, M | 1 |
Lie, R | 1 |
Rodenburg, CJ | 1 |
Veltkamp, JJ | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Pilot, Pharmacodynamic Correlate Trial of Sirolimus in Combination With Chemotherapy (Idarubicin, Cytarabine) for the Treatment of Newly Diagnosed Acute Myelogenous Leukemia[NCT01822015] | Early Phase 1 | 55 participants (Actual) | Interventional | 2013-03-15 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for amsacrine and Vomiting
Article | Year |
---|---|
Current status of amsacrine (AMSA) combination chemotherapy programs in acute leukemia.
Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical T | 1983 |
2 trials available for amsacrine and Vomiting
Article | Year |
---|---|
Current status of amsacrine (AMSA) combination chemotherapy programs in acute leukemia.
Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical T | 1983 |
Comparison of efficacies of ondansetron and dixyrazine for prophylaxis of emesis during induction treatment in acute myelogenous leukemia. A pilot study.
Topics: Adult; Aged; Aged, 80 and over; Amsacrine; Antiemetics; Antineoplastic Combined Chemotherapy Protoco | 1997 |
5 other studies available for amsacrine and Vomiting
Article | Year |
---|---|
High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemother | 1984 |
Phase II trial of amsacrine (m-AMSA) in advanced ovarian carcinoma.
Topics: Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Female; Humans; Leuk | 1982 |
Phase II study of m-AMSA in advances malignant melanoma.
Topics: Adult; Aged; Aminoacridines; Amsacrine; Drug Evaluation; Female; Humans; Leukopenia; Male; Melanoma; | 1982 |
Amsacrine (AMSA).
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Breast Neoplasms; Dogs; Dose-Response Rel | 1980 |
Intermediate and high-dose ARA-C and m-AMSA (or daunorubicin) as remission and consolidation treatment for patients with relapsed acute leukaemia and lymphoblastic non-Hodgkin lymphoma.
Topics: Adolescent; Adult; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytara | 1985 |