Page last updated: 2024-10-22

amsacrine and Vomiting

amsacrine has been researched along with Vomiting in 7 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"Leukopenia was found to be dose-limiting; thrombocytopenia and anemia were also observed."1.26Phase II study of m-AMSA in advances malignant melanoma. ( Arseneau, JC; Kuperminc, M; Probert, JC; Wolter, JM, 1982)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hines, JD1
Oken, MM1
Mazza, JJ1
Keller, AM1
Streeter, RR1
Glick, JH1
Arlin, ZA1
Dombernowsky, P1
Siegenthaler, P1
Somers, R1
Hansen, HH1
Arseneau, JC1
Wolter, JM1
Probert, JC1
Kuperminc, M1
Issell, BF1
Sundström, GM1
Wahlin, A1
Willemze, R1
Peters, WG1
van Hennik, MB1
Fibbe, WE1
Kootte, AM1
van Berkel, M1
Lie, R1
Rodenburg, CJ1
Veltkamp, JJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot, Pharmacodynamic Correlate Trial of Sirolimus in Combination With Chemotherapy (Idarubicin, Cytarabine) for the Treatment of Newly Diagnosed Acute Myelogenous Leukemia[NCT01822015]Early Phase 155 participants (Actual)Interventional2013-03-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for amsacrine and Vomiting

ArticleYear
Current status of amsacrine (AMSA) combination chemotherapy programs in acute leukemia.
    Cancer treatment reports, 1983, Volume: 67, Issue:11

    Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical T

1983

Trials

2 trials available for amsacrine and Vomiting

ArticleYear
Current status of amsacrine (AMSA) combination chemotherapy programs in acute leukemia.
    Cancer treatment reports, 1983, Volume: 67, Issue:11

    Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical T

1983
Comparison of efficacies of ondansetron and dixyrazine for prophylaxis of emesis during induction treatment in acute myelogenous leukemia. A pilot study.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amsacrine; Antiemetics; Antineoplastic Combined Chemotherapy Protoco

1997

Other Studies

5 other studies available for amsacrine and Vomiting

ArticleYear
High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemother

1984
Phase II trial of amsacrine (m-AMSA) in advanced ovarian carcinoma.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:1

    Topics: Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Female; Humans; Leuk

1982
Phase II study of m-AMSA in advances malignant melanoma.
    American journal of clinical oncology, 1982, Volume: 5, Issue:4

    Topics: Adult; Aged; Aminoacridines; Amsacrine; Drug Evaluation; Female; Humans; Leukopenia; Male; Melanoma;

1982
Amsacrine (AMSA).
    Cancer treatment reviews, 1980, Volume: 7, Issue:2

    Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Breast Neoplasms; Dogs; Dose-Response Rel

1980
Intermediate and high-dose ARA-C and m-AMSA (or daunorubicin) as remission and consolidation treatment for patients with relapsed acute leukaemia and lymphoblastic non-Hodgkin lymphoma.
    Scandinavian journal of haematology, 1985, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytara

1985