Page last updated: 2024-10-22

amsacrine and Urinary Bladder Neoplasms

amsacrine has been researched along with Urinary Bladder Neoplasms in 6 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.

Research Excerpts

ExcerptRelevanceReference
"But amsacrine has been forgotten in clinical studies of transitional cell carcinoma of the urinary bladder."2.70Amsacrine and cisplatin in poor prognosis patients with metastatic transitional cell carcinoma of the urothelium: a phase-II study. ( Jelíc, S; Nikolíc-Tomasevíc, Z; Popov, I; Radosavljevíc, D, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friedell, GH1
Natale, RB1
Yagoda, A1
Blumenreich, MS1
Watson, RC1
Trump, DL1
Loening, S1
Ahmed, SW1
Wajsman, Z1
Popov, I1
Jelíc, S1
Radosavljevíc, D1
Nikolíc-Tomasevíc, Z1
Fry, AM1
Chresta, CM1
Davies, SM1
Walker, MC1
Harris, AL1
Hartley, JA1
Masters, JR1
Hickson, ID1
Al-Sarraf, M1
Frank, J1
Smith, JA1
O'Bryan, RM1
Costanzi, JJ1
Stephens, RL1
Caraveo, J1
Crawford, ED1

Trials

3 trials available for amsacrine and Urinary Bladder Neoplasms

ArticleYear
Bladder cancer chemotherapy studies supported by the National Bladder Cancer Project.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11 Suppl

    Topics: Adult; Aminoacridines; Amsacrine; Antineoplastic Agents; Carcinoma in Situ; Carcinoma, Papillary; Ci

1983
Amsacrine and cisplatin in poor prognosis patients with metastatic transitional cell carcinoma of the urothelium: a phase-II study.
    European urology, 2001, Volume: 40, Issue:3

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell

2001
Phase II trial of cyclophosphamide, doxorubicin, and cisplatin (CAP) versus amsacrine in patients with transitional cell carcinoma of the urinary bladder: a Southwest Oncology Group study.
    Cancer treatment reports, 1985, Volume: 69, Issue:2

    Topics: Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transiti

1985

Other Studies

3 other studies available for amsacrine and Urinary Bladder Neoplasms

ArticleYear
Phase II trial of amsacrine (AMSA) in urinary bladder cancer.
    Cancer treatment reports, 1983, Volume: 67, Issue:4

    Topics: Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Female; Humans; Leuk

1983
Phase II study of amsacrine (AMSA) in previously treated patients with advanced transitional cell carcinoma of the urothelium: a National Bladder Cancer Collaborative Group A study.
    Cancer treatment reports, 1983, Volume: 67, Issue:9

    Topics: Aminoacridines; Amsacrine; Carcinoma, Transitional Cell; Drug Evaluation; Epithelium; Humans; Kidney

1983
Relationship between topoisomerase II level and chemosensitivity in human tumor cell lines.
    Cancer research, 1991, Dec-15, Volume: 51, Issue:24

    Topics: Amsacrine; Blotting, Western; Cell Death; Cross-Linking Reagents; DNA Damage; DNA Topoisomerases, Ty

1991