Page last updated: 2024-10-22

amsacrine and Primary Myelofibrosis

amsacrine has been researched along with Primary Myelofibrosis in 1 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Primary Myelofibrosis: A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.

Research Excerpts

ExcerptRelevanceReference
"Amsacrine and VP-16 were given without success."2.38Acute megakaryoblastic leukemia: a case report. ( Donhuijsen-Ant, R; Leder, LD; Löffler, H; Schadeck-Gressel, C; Schmidt, U; Westerhausen, M, 1990)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Donhuijsen-Ant, R1
Schadeck-Gressel, C1
Schmidt, U1
Löffler, H1
Westerhausen, M1
Leder, LD1

Reviews

1 review available for amsacrine and Primary Myelofibrosis

ArticleYear
Acute megakaryoblastic leukemia: a case report.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Acid Phosphatase; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyta

1990