amsacrine has been researched along with Pancreatic Neoplasms in 5 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (60.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Perni, RB | 1 |
Wentland, MP | 1 |
Huang, JI | 1 |
Powles, RG | 1 |
Aldous, S | 1 |
Klingbeil, KM | 1 |
Peverly, AD | 1 |
Robinson, RG | 1 |
Corbett, TH | 1 |
Jones, JL | 1 |
Mattes, KC | 1 |
Rake, JB | 1 |
Coughlin, SA | 1 |
Omura, GA | 1 |
Bartolucci, AA | 1 |
Lessner, HE | 1 |
Hill, GJ | 1 |
Inamasu, M | 1 |
Oishi, N | 1 |
Chen, T | 1 |
Legha, S | 1 |
McCracken, J | 1 |
Balcerzak, S | 1 |
Stephens, R | 1 |
O'Bryan, R | 1 |
Rivkin, SE | 1 |
Costanzi, JJ | 1 |
Sternberg, CN | 1 |
Magill, GB | 1 |
Sordillo, PP | 1 |
Cheng, E | 1 |
Currie, VE | 1 |
Sohn, TA | 1 |
Bansal, R | 1 |
Su, GH | 1 |
Murphy, KM | 1 |
Kern, SE | 1 |
5 other studies available for amsacrine and Pancreatic Neoplasms
Article | Year |
---|---|
Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enz | 1998 |
Phase II evaluation of amsacrine in colorectal, gastric, and pancreatic carcinomas: a Southeastern Cancer Study Group trial.
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Female; Gastro | 1984 |
Phase II trial of amsacrine in pancreatic carcinoma: a Southwest Oncology Group study.
Topics: Adult; Aged; Aminoacridines; Amsacrine; Carcinoma; Drug Evaluation; Humans; Middle Aged; Pancreatic | 1984 |
Phase II evaluation of m-AMSA (4'-(9-acridinylamino)-methanesulfon-m-anisidide) in patients with adenocarcinoma of the pancreas.
Topics: Adenocarcinoma; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Female; Hum | 1983 |
High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter.
Topics: Amsacrine; Anticarcinogenic Agents; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Gene Ex | 2002 |