amsacrine has been researched along with Pancreatic Neoplasms in 5 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perni, RB | 1 |
| Wentland, MP | 1 |
| Huang, JI | 1 |
| Powles, RG | 1 |
| Aldous, S | 1 |
| Klingbeil, KM | 1 |
| Peverly, AD | 1 |
| Robinson, RG | 1 |
| Corbett, TH | 1 |
| Jones, JL | 1 |
| Mattes, KC | 1 |
| Rake, JB | 1 |
| Coughlin, SA | 1 |
| Omura, GA | 1 |
| Bartolucci, AA | 1 |
| Lessner, HE | 1 |
| Hill, GJ | 1 |
| Inamasu, M | 1 |
| Oishi, N | 1 |
| Chen, T | 1 |
| Legha, S | 1 |
| McCracken, J | 1 |
| Balcerzak, S | 1 |
| Stephens, R | 1 |
| O'Bryan, R | 1 |
| Rivkin, SE | 1 |
| Costanzi, JJ | 1 |
| Sternberg, CN | 1 |
| Magill, GB | 1 |
| Sordillo, PP | 1 |
| Cheng, E | 1 |
| Currie, VE | 1 |
| Sohn, TA | 1 |
| Bansal, R | 1 |
| Su, GH | 1 |
| Murphy, KM | 1 |
| Kern, SE | 1 |
5 other studies available for amsacrine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enz | 1998 |
Phase II evaluation of amsacrine in colorectal, gastric, and pancreatic carcinomas: a Southeastern Cancer Study Group trial.
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Female; Gastro | 1984 |
Phase II trial of amsacrine in pancreatic carcinoma: a Southwest Oncology Group study.
Topics: Adult; Aged; Aminoacridines; Amsacrine; Carcinoma; Drug Evaluation; Humans; Middle Aged; Pancreatic | 1984 |
Phase II evaluation of m-AMSA (4'-(9-acridinylamino)-methanesulfon-m-anisidide) in patients with adenocarcinoma of the pancreas.
Topics: Adenocarcinoma; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Female; Hum | 1983 |
High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter.
Topics: Amsacrine; Anticarcinogenic Agents; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Gene Ex | 2002 |