Page last updated: 2024-10-22

amsacrine and Pancreatic Neoplasms

amsacrine has been researched along with Pancreatic Neoplasms in 5 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Perni, RB1
Wentland, MP1
Huang, JI1
Powles, RG1
Aldous, S1
Klingbeil, KM1
Peverly, AD1
Robinson, RG1
Corbett, TH1
Jones, JL1
Mattes, KC1
Rake, JB1
Coughlin, SA1
Omura, GA1
Bartolucci, AA1
Lessner, HE1
Hill, GJ1
Inamasu, M1
Oishi, N1
Chen, T1
Legha, S1
McCracken, J1
Balcerzak, S1
Stephens, R1
O'Bryan, R1
Rivkin, SE1
Costanzi, JJ1
Sternberg, CN1
Magill, GB1
Sordillo, PP1
Cheng, E1
Currie, VE1
Sohn, TA1
Bansal, R1
Su, GH1
Murphy, KM1
Kern, SE1

Other Studies

5 other studies available for amsacrine and Pancreatic Neoplasms

ArticleYear
Synthesis and antitumor activity of 4-aminomethylthioxanthenone and 5-aminomethylbenzothiopyranoindazole derivatives.
    Journal of medicinal chemistry, 1998, Sep-10, Volume: 41, Issue:19

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Enz

1998
Phase II evaluation of amsacrine in colorectal, gastric, and pancreatic carcinomas: a Southeastern Cancer Study Group trial.
    Cancer treatment reports, 1984, Volume: 68, Issue:6

    Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Female; Gastro

1984
Phase II trial of amsacrine in pancreatic carcinoma: a Southwest Oncology Group study.
    Cancer treatment reports, 1984, Volume: 68, Issue:11

    Topics: Adult; Aged; Aminoacridines; Amsacrine; Carcinoma; Drug Evaluation; Humans; Middle Aged; Pancreatic

1984
Phase II evaluation of m-AMSA (4'-(9-acridinylamino)-methanesulfon-m-anisidide) in patients with adenocarcinoma of the pancreas.
    American journal of clinical oncology, 1983, Volume: 6, Issue:4

    Topics: Adenocarcinoma; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Female; Hum

1983
High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter.
    Carcinogenesis, 2002, Volume: 23, Issue:6

    Topics: Amsacrine; Anticarcinogenic Agents; Antineoplastic Agents; Cell Survival; Colonic Neoplasms; Gene Ex

2002