amsacrine has been researched along with Neutropenia in 9 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with acute leukemia in relapse were given 5'-(9-acridinylamino)methanesulfon-m-anisidide at a dosage of 75 to 200 mg/sq m as a daily bolus infusion of 5 consecutive days." | 1.26 | Phase I and II trial of 4'-(9-acridinylamino)methanesulfon-m-anisidide in patients with acute leukemia. ( Arlin, ZA; Clarkson, BD; Gee, TS; Howard, J; Kempin, SJ; Sklaroff, RB; Young, CW, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arlin, ZA | 1 |
| Sklaroff, RB | 1 |
| Gee, TS | 1 |
| Kempin, SJ | 1 |
| Howard, J | 1 |
| Clarkson, BD | 1 |
| Young, CW | 1 |
| Ong, ST | 1 |
| Kueh, YK | 1 |
| Möllgård, L | 1 |
| Tidefelt, U | 1 |
| Sundman-Engberg, B | 1 |
| Löfgren, C | 1 |
| Lehman, S | 1 |
| Paul, C | 1 |
| Harousseau, JL | 2 |
| Witz, B | 1 |
| Lioure, B | 1 |
| Hunault-Berger, M | 1 |
| Desablens, B | 2 |
| Delain, M | 1 |
| Guilhot, F | 1 |
| Le Prise, PY | 2 |
| Abgrall, JF | 1 |
| Deconinck, E | 1 |
| Guyotat, D | 1 |
| Vilque, JP | 1 |
| Casassus, P | 2 |
| Tournilhac, O | 1 |
| Audhuy, B | 1 |
| Solary, E | 1 |
| Dreyfus, F | 1 |
| Leblond, V | 1 |
| Belanger, C | 1 |
| Gabarre, J | 1 |
| Sutton, L | 1 |
| Boccaccio, C | 1 |
| Quarre, MC | 1 |
| Ribrag, V | 1 |
| Goy, A | 1 |
| Harvey, VJ | 1 |
| Hardy, JR | 1 |
| Smith, S | 1 |
| Grove, W | 1 |
| Baguley, BC | 1 |
| Milpied, N | 1 |
| Briere, J | 1 |
| Ifrah, N | 1 |
| Gandhour, C | 1 |
| Dhaliwal, HS | 1 |
| Shannon, MS | 1 |
| Barnett, MJ | 1 |
| Prentice, HG | 1 |
| Bragman, K | 1 |
| Malpas, JS | 1 |
| Lister, TA | 1 |
| Civin, CI | 1 |
| Krischer, JP | 1 |
| Land, VJ | 1 |
| Nitschke, R | 1 |
| Kamen, B | 1 |
| Vats, T | 1 |
2 trials available for amsacrine and Neutropenia
| Article | Year |
|---|---|
High single dose of mitoxantrone and cytarabine in acute non-lymphocytic leukemia: a pharmacokinetic and clinical study.
Topics: Adult; Aged; Amsacrine; Chromatography, High Pressure Liquid; Cytarabine; Drug Administration Schedu | 1998 |
Granulocyte colony-stimulating factor after intensive consolidation chemotherapy in acute myeloid leukemia: results of a randomized trial of the Groupe Ouest-Est Leucémies Aigues Myeloblastiques.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; | 2000 |
7 other studies available for amsacrine and Neutropenia
| Article | Year |
|---|---|
Phase I and II trial of 4'-(9-acridinylamino)methanesulfon-m-anisidide in patients with acute leukemia.
Topics: Adolescent; Adult; Aminoacridines; Amsacrine; Drug Administration Schedule; Drug Evaluation; Humans; | 1980 |
Hepatic candidiasis: persistent pyrexia in a patient with acute myeloid leukaemia after recovery from consolidation therapy-induced neutropenia.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Candidiasis; Cytosine; Eto | 1993 |
Peripheral blood stem cell collection and autografting in high risk lymphomas.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Blood Tra | 1992 |
Phase II study of the amsacrine analogue CI-921 (NSC 343499) in non-small cell lung cancer.
Topics: Adult; Aged; Amsacrine; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Fema | 1991 |
Double intensive consolidation chemotherapy (ICC) for acute myeloid leukemia.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmu | 1990 |
Treatment of acute leukaemia with m-AMSA in combination with cytosine arabinoside.
Topics: Aged; Amsacrine; Chemical and Drug Induced Liver Injury; Cytarabine; Female; Gastrointestinal Diseas | 1986 |
Pediatric oncology group phase II trial of amsacrine in children with solid tumors.
Topics: Age Factors; Aminoacridines; Amsacrine; Arrhythmias, Cardiac; Child; Child, Preschool; Drug Evaluati | 1985 |