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amsacrine and Necrosis

amsacrine has been researched along with Necrosis in 5 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to fabricate and investigate amsacrine containing polymeric rods for use in interstitial chemotherapy of malignant glioma."7.69Polymeric controlled-release amsacrine chemotherapy in an experimental glioma model. ( Almqvist, PM; Boëthius, J; Glantz, MJ; Wahlberg, LU, 1996)
"The authors report a case of focal myocardial necrosis, presenting clinically as an acute myocardial infarction during the administration of the antineoplastic drug, amsacrine, in a patient without coronary artery disease."7.67Acute myocardial necrosis during administration of amsacrine. ( Burns, CP; Lindpaintner, K; Lindpaintner, LS; Wentworth, M, 1986)
"The purpose of this study was to fabricate and investigate amsacrine containing polymeric rods for use in interstitial chemotherapy of malignant glioma."3.69Polymeric controlled-release amsacrine chemotherapy in an experimental glioma model. ( Almqvist, PM; Boëthius, J; Glantz, MJ; Wahlberg, LU, 1996)
"The authors report a case of focal myocardial necrosis, presenting clinically as an acute myocardial infarction during the administration of the antineoplastic drug, amsacrine, in a patient without coronary artery disease."3.67Acute myocardial necrosis during administration of amsacrine. ( Burns, CP; Lindpaintner, K; Lindpaintner, LS; Wentworth, M, 1986)
"A case of necrotizing fasciitis of the vulva arising in a leukemic patient during a chemotherapy nadir is presented."1.28Necrotizing fasciitis of the vulva during chemotherapy. ( Hoffman, MS; Turnquist, D, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, G1
Qi, X1
Mo, X1
Yu, G1
Wang, Q1
Zhu, T1
Gu, Q1
Liu, M1
Li, J1
Li, D1
Morris, SM1
Domon, OE1
McGarrity, LJ1
Chen, JJ1
Casciano, DA1
Wahlberg, LU1
Almqvist, PM1
Glantz, MJ1
Boëthius, J1
Hoffman, MS1
Turnquist, D1
Lindpaintner, K1
Lindpaintner, LS1
Wentworth, M1
Burns, CP1

Other Studies

5 other studies available for amsacrine and Necrosis

ArticleYear
Structure-based discovery of cytotoxic dimeric tetrahydroxanthones as potential topoisomerase I inhibitors from a marine-derived fungus.
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Antineoplastic Agents; Aspergillus; Cell Cycle Checkpoints; Cell Line, Tumor; Dimerization; Drug Dis

2018
Programmed cell death and mutation induction in AHH-1 human lymphoblastoid cells exposed to m-amsa.
    Mutation research, 1995, Volume: 329, Issue:1

    Topics: Amsacrine; Analysis of Variance; Apoptosis; B-Lymphocytes; Cell Cycle; Cell Line, Transformed; Cell

1995
Polymeric controlled-release amsacrine chemotherapy in an experimental glioma model.
    Acta neurochirurgica, 1996, Volume: 138, Issue:11

    Topics: Amsacrine; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Division; Delayed-Actio

1996
Necrotizing fasciitis of the vulva during chemotherapy.
    Obstetrics and gynecology, 1989, Volume: 74, Issue:3 Pt 2

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fasciitis; Female; Hum

1989
Acute myocardial necrosis during administration of amsacrine.
    Cancer, 1986, Apr-01, Volume: 57, Issue:7

    Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Electrocardiography; Female; Humans; Leukemia; Mid

1986