amsacrine has been researched along with Necrosis in 5 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to fabricate and investigate amsacrine containing polymeric rods for use in interstitial chemotherapy of malignant glioma." | 7.69 | Polymeric controlled-release amsacrine chemotherapy in an experimental glioma model. ( Almqvist, PM; Boëthius, J; Glantz, MJ; Wahlberg, LU, 1996) |
| "The authors report a case of focal myocardial necrosis, presenting clinically as an acute myocardial infarction during the administration of the antineoplastic drug, amsacrine, in a patient without coronary artery disease." | 7.67 | Acute myocardial necrosis during administration of amsacrine. ( Burns, CP; Lindpaintner, K; Lindpaintner, LS; Wentworth, M, 1986) |
| "The purpose of this study was to fabricate and investigate amsacrine containing polymeric rods for use in interstitial chemotherapy of malignant glioma." | 3.69 | Polymeric controlled-release amsacrine chemotherapy in an experimental glioma model. ( Almqvist, PM; Boëthius, J; Glantz, MJ; Wahlberg, LU, 1996) |
| "The authors report a case of focal myocardial necrosis, presenting clinically as an acute myocardial infarction during the administration of the antineoplastic drug, amsacrine, in a patient without coronary artery disease." | 3.67 | Acute myocardial necrosis during administration of amsacrine. ( Burns, CP; Lindpaintner, K; Lindpaintner, LS; Wentworth, M, 1986) |
| "A case of necrotizing fasciitis of the vulva arising in a leukemic patient during a chemotherapy nadir is presented." | 1.28 | Necrotizing fasciitis of the vulva during chemotherapy. ( Hoffman, MS; Turnquist, D, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, G | 1 |
| Qi, X | 1 |
| Mo, X | 1 |
| Yu, G | 1 |
| Wang, Q | 1 |
| Zhu, T | 1 |
| Gu, Q | 1 |
| Liu, M | 1 |
| Li, J | 1 |
| Li, D | 1 |
| Morris, SM | 1 |
| Domon, OE | 1 |
| McGarrity, LJ | 1 |
| Chen, JJ | 1 |
| Casciano, DA | 1 |
| Wahlberg, LU | 1 |
| Almqvist, PM | 1 |
| Glantz, MJ | 1 |
| Boëthius, J | 1 |
| Hoffman, MS | 1 |
| Turnquist, D | 1 |
| Lindpaintner, K | 1 |
| Lindpaintner, LS | 1 |
| Wentworth, M | 1 |
| Burns, CP | 1 |
5 other studies available for amsacrine and Necrosis
| Article | Year |
|---|---|
Structure-based discovery of cytotoxic dimeric tetrahydroxanthones as potential topoisomerase I inhibitors from a marine-derived fungus.
Topics: Antineoplastic Agents; Aspergillus; Cell Cycle Checkpoints; Cell Line, Tumor; Dimerization; Drug Dis | 2018 |
Programmed cell death and mutation induction in AHH-1 human lymphoblastoid cells exposed to m-amsa.
Topics: Amsacrine; Analysis of Variance; Apoptosis; B-Lymphocytes; Cell Cycle; Cell Line, Transformed; Cell | 1995 |
Polymeric controlled-release amsacrine chemotherapy in an experimental glioma model.
Topics: Amsacrine; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Division; Delayed-Actio | 1996 |
Necrotizing fasciitis of the vulva during chemotherapy.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fasciitis; Female; Hum | 1989 |
Acute myocardial necrosis during administration of amsacrine.
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Electrocardiography; Female; Humans; Leukemia; Mid | 1986 |