amsacrine has been researched along with Lymph Node Metastasis in 2 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 117 primary breast cancers, 25 were amplified for erbB2." | 5.29 | Topoisomerase II alpha co-amplification with erbB2 in human primary breast cancer and breast cancer cell lines: relationship to m-AMSA and mitoxantrone sensitivity. ( Carmichael, J; Greenall, M; Harris, AL; Houlbrook, S; Smith, K, 1993) |
| "In 117 primary breast cancers, 25 were amplified for erbB2." | 1.29 | Topoisomerase II alpha co-amplification with erbB2 in human primary breast cancer and breast cancer cell lines: relationship to m-AMSA and mitoxantrone sensitivity. ( Carmichael, J; Greenall, M; Harris, AL; Houlbrook, S; Smith, K, 1993) |
| "Leukopenia was the dose-limiting toxicity with 7." | 1.27 | The treatment of melanoma with m-AMSA. A Cancer and Leukemia Group B phase II study. ( Amrein, PC; Carey, RW; Coleman, M; Green, MR; Holland, JF; Kennedy, BJ; Poulin, RF; Richards, F; Weil, M; Weinberg, V, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amrein, PC | 1 |
| Poulin, RF | 1 |
| Coleman, M | 1 |
| Richards, F | 1 |
| Weil, M | 1 |
| Kennedy, BJ | 1 |
| Carey, RW | 1 |
| Green, MR | 1 |
| Holland, JF | 1 |
| Weinberg, V | 1 |
| Smith, K | 1 |
| Houlbrook, S | 1 |
| Greenall, M | 1 |
| Carmichael, J | 1 |
| Harris, AL | 1 |
2 other studies available for amsacrine and Lymph Node Metastasis
| Article | Year |
|---|---|
The treatment of melanoma with m-AMSA. A Cancer and Leukemia Group B phase II study.
Topics: Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Female; Humans; Leuk | 1984 |
Topoisomerase II alpha co-amplification with erbB2 in human primary breast cancer and breast cancer cell lines: relationship to m-AMSA and mitoxantrone sensitivity.
Topics: Adult; Aged; Amsacrine; Breast Neoplasms; DNA Topoisomerases, Type II; DNA, Neoplasm; ErbB Receptors | 1993 |