amsacrine has been researched along with Leukemia L5178 in 5 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Leukemia L5178: An experimental lymphocytic leukemia of mice.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lanza, A | 1 |
| Tornaletti, S | 1 |
| Stefanini, M | 1 |
| Evans, HH | 2 |
| Ricanati, M | 2 |
| Astaldi Ricotti, GC | 1 |
| Pedrini, AM | 1 |
| Stopper, H | 1 |
| Eckert, I | 1 |
| Wagener, P | 1 |
| Schulz, WA | 1 |
| Doerr, CL | 2 |
| Harrington-Brock, K | 1 |
| Moore, MM | 2 |
| Horng, MF | 1 |
| Mencl, J | 1 |
| DeMarini, DM | 1 |
| Meyer, MK | 1 |
| Brock, KH | 1 |
| Hozier, J | 1 |
5 other studies available for amsacrine and Leukemia L5178
| Article | Year |
|---|---|
The sensitivity to DNA topoisomerase inhibitors in L5178Y lymphoma strains is not related to a primary defect of DNA topoisomerases.
Topics: Amsacrine; Animals; Camptothecin; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type I | 1993 |
Formation of micronuclei and inhibition of topoisomerase II in the comet assay in mammalian cells with altered DNA methylation.
Topics: Amsacrine; Animals; Azacitidine; Carcinoma, Embryonal; Cell Differentiation; DNA Methylation; DNA, N | 1997 |
Micronucleus, chromosome aberration, and small-colony TK mutant analysis to quantitate chromosomal damage in L5178Y mouse lymphoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoacridines; Amsacrine; Animals; Bleomycin; Chromosome Aberrati | 1989 |
Relationship between topoisomerase II and radiosensitivity in mouse L5178Y lymphoma strains.
Topics: Amsacrine; Animals; Cells, Cultured; DNA Repair; DNA Topoisomerases, Type II; Ellipticines; Etoposid | 1989 |
Mutagenicity of m-AMSA and o-AMSA in mammalian cells due to clastogenic mechanism: possible role of topoisomerase.
Topics: Amsacrine; Animals; Cell Survival; Chromosome Aberrations; DNA Topoisomerases, Type II; Hypoxanthine | 1987 |