amsacrine has been researched along with Leukemia L 1210 in 65 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both hybrid compounds are more cytotoxic than etoposide but much less toxic than amsacrine toward L1210 leukemia cells." | 1.31 | Design of two etoposide-amsacrine conjugates: topoisomerase II and tubuline polymerization inhibition and relation to cytotoxicity. ( Arimondo, P; Bailly, C; Boukarim, C; Dauzonne, D; Monneret, C, 2000) |
| "with either L1210 cells or Ehrlich ascites tumor cells." | 1.29 | ICRF-187 rescue in etoposide treatment in vivo. A model targeting high-dose topoisomerase II poisons to CNS tumors. ( Holm, B; Jensen, PB; Sehested, M, 1996) |
| "The antitumor drug amsacrine causes chromosomal aberrations both in cultured cells (L1210 murine leukemia and HeLa cells) and in vivo (L1210 leukemia)." | 1.27 | Relationship between the induction of chromosome damage and cytotoxicity for amsacrine and congeners. ( Baguley, BC; Ferguson, LR, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 51 (78.46) | 18.7374 |
| 1990's | 13 (20.00) | 18.2507 |
| 2000's | 1 (1.54) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sinha, BK | 1 |
| Cysyk, RL | 1 |
| Millar, DB | 1 |
| Chignell, CF | 1 |
| Denny, WA | 16 |
| Atwell, GJ | 12 |
| Cain, BF | 8 |
| Baguley, BC | 18 |
| Finlay, GJ | 4 |
| Rewcastle, GW | 5 |
| Ferguson, LR | 3 |
| Pommier, Y | 14 |
| Schwartz, RE | 6 |
| Kohn, KW | 14 |
| Zwelling, LA | 12 |
| Minford, J | 1 |
| Kerrigan, D | 9 |
| Nichols, M | 2 |
| Shackney, S | 1 |
| Wilson, WR | 2 |
| Tapp, SM | 1 |
| Twigden, SJ | 1 |
| Mattern, MR | 4 |
| Filipski, J | 1 |
| Yin, J | 1 |
| Michaels, S | 3 |
| Erickson, LC | 1 |
| Ungerleider, RS | 1 |
| Nash, R | 1 |
| Dumont, P | 1 |
| Atassi, G | 1 |
| Tagnon, HJ | 1 |
| Robertson, IG | 1 |
| Barret, JM | 1 |
| Calsou, P | 1 |
| Larsen, AK | 1 |
| Salles, B | 1 |
| Vichi, PJ | 1 |
| Tritton, TR | 1 |
| Kirshenbaum, MR | 1 |
| Chen, SF | 1 |
| Behrens, CH | 1 |
| Papp, LM | 1 |
| Stafford, MM | 1 |
| Sun, JH | 1 |
| Behrens, DL | 1 |
| Fredericks, JR | 1 |
| Polkus, ST | 1 |
| Sipple, P | 1 |
| Jensen, PB | 2 |
| Sørensen, BS | 1 |
| Sehested, M | 2 |
| Grue, P | 1 |
| Demant, EJ | 1 |
| Hansen, HH | 1 |
| Llama, E | 1 |
| Del Campo, C | 1 |
| Capo, M | 1 |
| Anadon, M | 1 |
| Holm, B | 1 |
| Grabowski, D | 2 |
| Ganapathi, R | 2 |
| Gao, H | 1 |
| Garg, R | 1 |
| Hansch, C | 1 |
| Arimondo, P | 1 |
| Boukarim, C | 1 |
| Bailly, C | 3 |
| Dauzonne, D | 1 |
| Monneret, C | 1 |
| Orr, A | 2 |
| Riou, JF | 1 |
| Bailly, F | 1 |
| Helbecque, N | 2 |
| Pommery, N | 1 |
| Colson, P | 2 |
| Houssier, C | 2 |
| Hénichart, JP | 2 |
| Capranico, G | 1 |
| Ching, LM | 2 |
| Joseph, WR | 1 |
| Fry, DW | 1 |
| Boritzki, TJ | 1 |
| Besserer, JA | 1 |
| Jackson, RC | 1 |
| Woynarowski, JM | 3 |
| Sigmund, RD | 2 |
| Beerman, TA | 3 |
| Morier-Teissier, E | 1 |
| Bernier, JL | 1 |
| Houssin, R | 1 |
| Catteau, JP | 1 |
| Kohn, K | 1 |
| McNamee, H | 1 |
| Szmigiero, L | 1 |
| Konopa, J | 1 |
| Ford, J | 1 |
| Heiss, C | 1 |
| Pierson, V | 1 |
| Pierre, A | 1 |
| de Cointet, P | 1 |
| Nguyen, CH | 1 |
| Bisagni, E | 1 |
| Gros, P | 1 |
| Covey, J | 1 |
| Mattes, W | 1 |
| Markovits, J | 3 |
| Bakic, M | 1 |
| Chan, D | 1 |
| Freireich, EJ | 1 |
| Marton, LJ | 2 |
| Covey, JM | 2 |
| Tilchen, EJ | 2 |
| Schneider, E | 1 |
| Darkin, SJ | 1 |
| Lawson, PA | 1 |
| Ralph, RK | 1 |
| Minford, JK | 1 |
| Sullivan, DM | 1 |
| Glisson, BS | 1 |
| Hodges, PK | 1 |
| Smallwood-Kentro, S | 1 |
| Ross, WE | 1 |
| Esnault, C | 1 |
| Roques, BP | 1 |
| Le Pecq, JB | 1 |
| Mazerska, Z | 1 |
| Chołody, M | 1 |
| Lukowicz, J | 1 |
| Wysocka-Skrzela, B | 1 |
| Ledóchowski, A | 1 |
| Klopman, G | 1 |
| Macina, OT | 1 |
65 other studies available for amsacrine and Leukemia L 1210
| Article | Year |
|---|---|
Synthesis and biological properties of some spin-labeled 9-aminoacridines.
Topics: Acridines; Animals; Cells, Cultured; DNA; Electron Spin Resonance Spectroscopy; Escherichia coli; Le | 1976 |
Potential antitumor agents. 26. Anionic congeners of the 9-anilinoacridines.
Topics: Acridines; Animals; Antineoplastic Agents; Leukemia L1210; Mice; Mice, Inbred C3H; Mice, Inbred DBA; | 1978 |
Potenial antitumor agents. 28. Deoxyribonucleic acid polyintercalating agents.
Topics: Acridines; Animals; Antineoplastic Agents; Bacteriophages; DNA; DNA, Superhelical; DNA, Viral; Leuke | 1978 |
Potential antitumor agents. 22. Latentiated congeners of the 4'-(9-acridinylamino)methanesulfonanilides.
Topics: Anilides; Animals; Antineoplastic Agents; Leukemia L1210; Lipids; Mice; Mice, Inbred C3H; Mice, Inbr | 1977 |
Potential antitumor agents. 23. 4'-(9-Acridinylamino)alkanesulfonanilide congeners bearing hydrophilic functionality.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Leukemia L1210; Mice; Mice, Inbred C3 | 1977 |
Potential antitumor agents. 17. 9-Anilino-10-methylacridinium salts.
Topics: Acridines; Aniline Compounds; Animals; Antineoplastic Agents; Leukemia L1210; Mice; Mice, Inbred C3H | 1976 |
Potential antitumor agents. 47. 3'-Methylamino analogues of amsacrine with in vivo solid tumor activity.
Topics: Acridines; Aminoacridines; Amsacrine; Animals; Cell Line; Chemical Phenomena; Chemistry; Colonic Neo | 1986 |
Potential antitumor agents. 40. Orally active 4,5-disubstituted derivatives of amsacrine.
Topics: Administration, Oral; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; DNA; Female; Inject | 1984 |
Potential antitumor agents. 41. Analogues of amsacrine with electron-donor substituents in the anilino ring.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; | 1984 |
Potential antitumor agents. 38. 3-substituted 5-carboxamido derivatives of amsacrine.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Indicators | 1983 |
Potential antitumor agents. 39. Anilino ring geometry of amsacrine and derivatives: relationship to DNA binding and antitumor activity.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cattle; DNA; Drug Evaluation, Preclinical | 1983 |
Potential antitumor agents. 42. Structure-activity relationships for acridine-substituted dimethyl phosphoramidate derivatives of 9-anilinoacridine.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; DNA; Female; Leukemia L1210; Leukemia P38 | 1984 |
Potential antitumor agents. 35. Quantitative relationships between antitumor (L1210) potency and DNA binding for 4'-(9-acridinylamino)methanesulfon-m-anisidide analogues.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; | 1981 |
Potential antitumor agents. 33. Quantitative structure--activity relationships for mutagenic activity and antitumor activity of substituted 4'-(9-acridinylamino)methanesulfonanilide derivatives.
Topics: Aminoacridines; Animals; Antineoplastic Agents; Leukemia L1210; Mathematics; Mice; Mutagens; Salmone | 1980 |
Potential antitumor agents. 37. Organophosphorus derivatives of 9-anilinoacridine.
Topics: Aminoacridines; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; DNA; Leukemia L1210; | 1982 |
Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents.
Topics: Adenosine Triphosphate; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Binding Sites; Da | 1984 |
Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells.
Topics: Aminoacridines; Amsacrine; Animals; Bleomycin; Cell Survival; Cytarabine; Daunorubicin; DNA, Neoplas | 1984 |
Differential growth inhibition of cultured mammalian cells: comparison of clinical antitumour agents and amsacrine derivatives.
Topics: Alkylating Agents; Aminoacridines; Amsacrine; Animals; Antimetabolites, Antineoplastic; Antineoplast | 1984 |
Relationship between the induction of chromosome damage and cytotoxicity for amsacrine and congeners.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Chromosome Aber | 1984 |
Synthesis, antitumor activity, and DNA binding properties of a new derivative of amsacrine, N-5-dimethyl-9-[(2-methoxy-4-methylsulfonylamino) phenylamino]-4-acridinecarboxamide.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cattle; Cell Division; Cell Line; Cell Su | 1984 |
Absence of swiveling at sites of intercalator-induced protein-associated deoxyribonucleic acid strand breaks in mammalian cell nucleoids.
Topics: Aminoacridines; Amsacrine; Animals; Carbon Radioisotopes; Cell Nucleus; Deoxyribonucleoproteins; DNA | 1984 |
Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide.
Topics: Aminoacridines; Amsacrine; Animals; Benzamides; Cell Nucleus; Deoxyribonucleoproteins; DNA, Neoplasm | 1984 |
Absence of a requirement for long-range DNA torsional strain in the production of protein-associated DNA strand breaks in isolated mammalian cell nuclei by the DNA intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA).
Topics: Aminoacridines; Amsacrine; Animals; Cell Nucleus; Deoxyribonucleoproteins; DNA, Neoplasm; Dose-Respo | 1984 |
Reconstitution of intercalator-induced DNA scission by an active component from nuclear extracts.
Topics: Aminoacridines; Amsacrine; Animals; Carbon Radioisotopes; Cell Nucleus; DNA, Neoplasm; Intercalating | 1983 |
Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino) methanesulfon-m-anisidide and adriamycin.
Topics: Aminoacridines; Amsacrine; Animals; Biological Transport; Cell Survival; Deoxyribonucleoproteins; DN | 1981 |
Antitumour activity of substituted 9-anilinoacridines--comparison of in vivo and in vitro testing systems.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; DNA, Neop | 1981 |
Combination chemotherapy with AMSA on L1210 leukaemia and B16 melanoma.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Carmustine; Dacarbazine; Drug Therapy, Co | 1981 |
Cytotoxicity and DNA strand breaks by 5-iminodaunorubicin in mouse leukemia L1210 cells: comparison with adriamycin and 4'-(9-acridinylamino)methanesulfon-m-anisidide.
Topics: Aminoacridines; Amsacrine; Animals; Cell Survival; Cells, Cultured; Daunorubicin; DNA; Doxorubicin; | 1982 |
Cooperative sequestration of m-AMSA in L1210 cells.
Topics: Allosteric Regulation; Aminoacridines; Amsacrine; Animals; Azides; Cell Nucleus; Cells, Cultured; DN | 1982 |
Induction of petite formation in Saccharomyces cerevisiae by experimental antitumour agents. Structure--activity relationships for 9-anilinoacridines.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Kinetics; Leukemia L1210; Mice; Mutagens; | 1981 |
Inhibition of T4 bacteriophage yield by 9-anilinoacridines; comparison with in vivo antitumour activity.
Topics: Acridines; Aminoacridines; Amsacrine; Animals; DNA, Viral; Dose-Response Relationship, Drug; Leukemi | 1980 |
A cisplatin-resistant murine leukemia cell line exhibits increased topoisomerase II activity.
Topics: Amino Acid Sequence; Amsacrine; Animals; Blotting, Western; Cell Survival; Cisplatin; DNA Repair; DN | 1994 |
Protection from adriamycin cytotoxicity in L1210 cells by brefeldin A.
Topics: Amsacrine; Animals; Biological Transport; Brefeldin A; Cell Survival; Cyclopentanes; DNA Damage; DNA | 1993 |
(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Colonic | 1994 |
Targeting the cytotoxicity of topoisomerase II-directed epipodophyllotoxins to tumor cells in acidic environments.
Topics: Amsacrine; Animals; Carcinoma, Small Cell; Chloroquine; DNA Damage; DNA Topoisomerases, Type II; DNA | 1994 |
Synthesis and antitumor activity of pyrido-amsacrine analogues and related compounds.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; DNA, Neoplasm; Drug Stability; Leukemia L1 | 1993 |
ICRF-187 rescue in etoposide treatment in vivo. A model targeting high-dose topoisomerase II poisons to CNS tumors.
Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; B | 1996 |
Cytotoxic efficacy with combinations of topoisomerase I and topoisomerase II inhibitors in sensitive and multidrug-resistant L1210 mouse leukemia cells.
Topics: Amsacrine; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothe | 1996 |
Quantitative structure-activity relationships (QSAR) for 9-anilinoacridines: a comparative analysis.
Topics: Amsacrine; Animals; Antineoplastic Agents; Drug Design; Kinetics; Leukemia L1210; Mice; Structure-Ac | 1998 |
Design of two etoposide-amsacrine conjugates: topoisomerase II and tubuline polymerization inhibition and relation to cytotoxicity.
Topics: Amsacrine; Animals; Base Sequence; Biopolymers; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposid | 2000 |
Differential effects of amsacrine and epipodophyllotoxins on topoisomerase II cleavage in the human c-myc protooncogene.
Topics: Amsacrine; Animals; Base Sequence; Binding Sites; Carcinoma, Small Cell; Cell Line; DNA Damage; DNA | 1992 |
Relationship between DNA-binding and biological activity of anilinoacridine derivatives containing the nucleic acid-binding unit SPKK.
Topics: Amino Acid Sequence; Amsacrine; Animals; Antineoplastic Agents; DNA-Binding Proteins; DNA, Neoplasm; | 1992 |
Distribution of topoisomerase II cleavage sites in simian virus 40 DNA and the effects of drugs.
Topics: Amsacrine; Animals; Base Sequence; Daunorubicin; DNA Damage; DNA Replication; DNA Topoisomerases, Ty | 1991 |
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neop | 1990 |
Comparison of the cytotoxicity of amsacrine and its analogue CI-921 against cultured human and mouse bone marrow tumour cells.
Topics: Amsacrine; Animals; Antineoplastic Agents; Bone Marrow; Cell Survival; Humans; Leukemia L1210; Leuke | 1990 |
In vitro DNA strand scission and inhibition of nucleic acid synthesis in L1210 leukemia cells by a new class of DNA complexers, the anthra[1,9-cd]pyrazol-6(2H)-ones (anthrapyrazoles).
Topics: Aminoacridines; Amsacrine; Animals; Anthraquinones; Colony-Forming Units Assay; DNA; Doxorubicin; Ki | 1985 |
DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells.
Topics: Amsacrine; Animals; Bisbenzimidazole; Cell Nucleus; Deoxyribonucleoproteins; Distamycins; DNA Damage | 1989 |
Synthesis, biological activity and DNA interaction of anilinoacridine and bithiazole peptide derivatives related to the anti-tumor drugs m-AMSA and bleomycin.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Bleomycin; Cattle; Chelating Agents; Chem | 1989 |
Topological complexes between DNA and topoisomerase II and effects of polyamines.
Topics: Amsacrine; Animals; DNA Topoisomerases, Type II; DNA, Viral; Kinetics; Leukemia L1210; Mice; Protein | 1989 |
Induction of DNA-protein crosslinks by antitumor 1-nitro-9-aminoacridines in L1210 leukemia cells.
Topics: Aminoacridines; Amsacrine; Animals; Cell Division; Cross-Linking Reagents; DNA Topoisomerases, Type | 1989 |
Progressive resistance to doxorubicin in mouse leukemia L1210 cells with multidrug resistance phenotype: reductions in drug-induced topoisomerase II-mediated DNA cleavage.
Topics: Amsacrine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Nucleus; Cell Surv | 1989 |
Interrelationship between affinity for DNA, cytotoxicity and induction of DNA-breaks in cultured L1210 cells for two series of tricyclic intercalators. Simplified analogues of ellipticine derivatives.
Topics: Alkaloids; Amsacrine; Animals; Cell Survival; DNA; DNA Damage; DNA, Neoplasm; Ellipticines; Intercal | 1989 |
Role of DNA intercalation in the inhibition of purified mouse leukemia (L1210) DNA topoisomerase II by 9-aminoacridines.
Topics: Aminoacridines; Amsacrine; Animals; Base Sequence; DNA; DNA Damage; Intercalating Agents; Leukemia L | 1987 |
Effect of polyamine depletion by alpha-difluoromethylornithine or (2R,5R)-6-heptyne-2,5-diamine on drug-induced topoisomerase II-mediated DNA cleavage and cytotoxicity in human and murine leukemia cells.
Topics: Alkynes; Amsacrine; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Diamines; DNA; DNA Dam | 1987 |
Topoisomerase II-mediated DNA damage produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity.
Topics: Aminoacridines; Amsacrine; Animals; Cell Nucleus; Cell Survival; DNA Damage; DNA Topoisomerases, Typ | 1988 |
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication | 1988 |
Cell line selectivity and DNA breakage properties of the antitumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide: role of DNA topoisomerase II.
Topics: Acridines; Aminacrine; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Survival; DNA | 1988 |
Effect of difluoromethylornithine, an inhibitor of polyamine biosynthesis, on the topoisomerase II-mediated DNA scission produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide in L1210 murine leukemia cells.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; DNA Topoisomerases, Type I; DNA, Neoplasm | 1985 |
Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage and strand passage.
Topics: Alkaloids; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Binding Sites; DNA Topoisomera | 1985 |
Effects of DNA intercalating agents on topoisomerase II induced DNA strand cleavage in isolated mammalian cell nuclei.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Nucleus; DNA Topoisomerases, Type II | 1985 |
Proliferation dependence of topoisomerase II mediated drug action.
Topics: Aminoacridines; Amsacrine; Animals; Cell Line; Cricetinae; Cricetulus; DNA Replication; DNA Topoisom | 1986 |
Effects of the bifunctional antitumor intercalator ditercalinium on DNA in mouse leukemia L1210 cells and DNA topoisomerase II.
Topics: Amsacrine; Animals; Carbazoles; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Etoposide; Interc | 1986 |
Topoisomerase II-mediated DNA breaks and cytotoxicity in relation to cell proliferation and the cell cycle in NIH 3T3 fibroblasts and L1210 leukemia cells.
Topics: Amsacrine; Animals; Cell Cycle; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA Topoisomera | 1987 |
Comparison of antitumor properties of nitracrine and amsacrine analogs.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; HeLa Cells; Humans; Lethal Dose 50; Leuke | 1987 |
Computer-automated structure evaluation of antileukemic 9-anilinoacridines.
Topics: Amsacrine; Animals; Antineoplastic Agents; Computer Simulation; Leukemia L1210; Software; Structure- | 1987 |