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amsacrine and Leukemia, Myelomonocytic, Acute

amsacrine has been researched along with Leukemia, Myelomonocytic, Acute in 8 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Leukemia, Myelomonocytic, Acute: A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of monocytic origin.

Research Excerpts

ExcerptRelevanceReference
"Forty-eight patients with acute myelogenous leukemia (AML) not eligible for anthracycline or mitoxantrone treatment, mostly due to cardiac contraindications, were given aggressive therapy using m-amsacrine (AMSA) in combination with conventional or high-dose cytarabine for remission induction."5.07AMSA combination chemotherapy in patients with acute myelogenous leukemia unsuitable for standard antileukemic treatment. ( Heit, W; Maschmeyer, G; Willborn, K, 1992)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fouillard, L1
Labopin, M1
Meloni, G1
Polge, E1
Gorin, NC1
Frassoni, F1
Fukushima, T1
Kuriyama, K1
Yoshida, S1
Nagai, K1
Miyazaki, Y1
Moriuti, Y1
Tomonaga, M1
Ong, ST1
Kueh, YK1
Wahlin, A1
Brinch, L1
Hörnsten, P1
Evensen, SA1
Oberg, G1
Simonsson, B1
Hedenus, M1
Nørgaard, JM1
Olesen, LH1
Olesen, G1
Meyer, K1
Kristensen, JS1
Bendix, K1
Pedersen, B1
Kjeldsen, E1
Hokland, P1
Maschmeyer, G1
Willborn, K1
Heit, W1
Jehn, U2
Zittoun, R1
Suciu, S1
Fiere, D1
Haanen, C1
Peetermans, M1
Löwenberg, B1
Willemze, R1
Solbu, G1
Stryckmans, P1
Heinemann, V1

Trials

4 trials available for amsacrine and Leukemia, Myelomonocytic, Acute

ArticleYear
Outcome of a multicenter treatment program including autologous or allogeneic bone marrow transplantation for de novo acute myeloid leukemia.
    European journal of haematology, 1997, Volume: 58, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Amsacrine; Antineoplastic Combined Chemotherapy Proto

1997
AMSA combination chemotherapy in patients with acute myelogenous leukemia unsuitable for standard antileukemic treatment.
    Leukemia & lymphoma, 1992, Volume: 8, Issue:4-5

    Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Heart Di

1992
A randomized comparison of intensive maintenance treatment for adult acute myelogenous leukemia using either cyclic alternating drugs or repeated courses of the induction-type chemotherapy: AML-6 trial of the EORTC Leukemia Cooperative Group.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bel

1990
Intermediate-dose Ara-C/m-AMSA for remission induction and high-dose Ara-C/m-AMSA for intensive consolidation in relapsed and refractory adult acute myelogeneous leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bon

1990

Other Studies

4 other studies available for amsacrine and Leukemia, Myelomonocytic, Acute

ArticleYear
Comparison of BAVC to BuCy regimens in autologous stem cell transplantation for adult patients with acute myeloid leukemia.
    Haematologica, 2004, Volume: 89, Issue:1

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmus

2004
[Allogeneic bone marrow transplantation for two patients with acute myeloid leukemia with trilineage myelodysplasia (T-MDS)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:2

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combi

1994
Hepatic candidiasis: persistent pyrexia in a patient with acute myeloid leukaemia after recovery from consolidation therapy-induced neutropenia.
    Annals of the Academy of Medicine, Singapore, 1993, Volume: 22, Issue:2

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Candidiasis; Cytosine; Eto

1993
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
    European journal of haematology, 2001, Volume: 67, Issue:4

    Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antigens, Neoplas

2001