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amsacrine and Leukemia, Megakaryoblastic, Acute

amsacrine has been researched along with Leukemia, Megakaryoblastic, Acute in 5 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Leukemia, Megakaryoblastic, Acute: An acute myeloid leukemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. MYELOFIBROSIS or increased bone marrow RETICULIN is common.

Research Excerpts

ExcerptRelevanceReference
"Amsacrine and VP-16 were given without success."2.38Acute megakaryoblastic leukemia: a case report. ( Donhuijsen-Ant, R; Leder, LD; Löffler, H; Schadeck-Gressel, C; Schmidt, U; Westerhausen, M, 1990)
"Amsacrine is an active antileukemic agent known to induce cardiac arrhythmias, although the incidence of these cardiac events is low."1.27Amsacrine is safe in patients with ventricular ectopy. ( Arlin, ZA; Feldman, EJ; Puccio, CA, 1988)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fouillard, L1
Labopin, M1
Meloni, G1
Polge, E1
Gorin, NC1
Frassoni, F1
Las Heras, G1
Ribera, JM1
Granada, I1
Millá, F1
Donhuijsen-Ant, R1
Schadeck-Gressel, C1
Schmidt, U1
Löffler, H1
Westerhausen, M1
Leder, LD1
Puccio, CA1
Feldman, EJ1
Arlin, ZA1
Simon, JH1
Tebbi, CK1
Freeman, AI1
Brecher, ML1
Green, DM1
Sandberg, AA1

Reviews

2 reviews available for amsacrine and Leukemia, Megakaryoblastic, Acute

ArticleYear
Acute megakaryoblastic leukemia: a case report.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Acid Phosphatase; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyta

1990
Acute megakaryoblastic leukemia associated with mosaic Down's syndrome.
    Cancer, 1987, Nov-15, Volume: 60, Issue:10

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 17; Clone Cells;

1987

Other Studies

3 other studies available for amsacrine and Leukemia, Megakaryoblastic, Acute

ArticleYear
Comparison of BAVC to BuCy regimens in autologous stem cell transplantation for adult patients with acute myeloid leukemia.
    Haematologica, 2004, Volume: 89, Issue:1

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmus

2004
[Acute myeloblastic leukemia 5q-. Clinical and cytogenetic remission by means of intensive chemotherapy].
    Sangre, 1991, Volume: 36, Issue:3

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human,

1991
Amsacrine is safe in patients with ventricular ectopy.
    American journal of hematology, 1988, Volume: 28, Issue:3

    Topics: Aged; Amsacrine; Cardiac Complexes, Premature; Cytarabine; Drug Therapy, Combination; Electrocardiog

1988