amsacrine has been researched along with Leukemia, Megakaryoblastic, Acute in 5 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Leukemia, Megakaryoblastic, Acute: An acute myeloid leukemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. MYELOFIBROSIS or increased bone marrow RETICULIN is common.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amsacrine and VP-16 were given without success." | 2.38 | Acute megakaryoblastic leukemia: a case report. ( Donhuijsen-Ant, R; Leder, LD; Löffler, H; Schadeck-Gressel, C; Schmidt, U; Westerhausen, M, 1990) |
| "Amsacrine is an active antileukemic agent known to induce cardiac arrhythmias, although the incidence of these cardiac events is low." | 1.27 | Amsacrine is safe in patients with ventricular ectopy. ( Arlin, ZA; Feldman, EJ; Puccio, CA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fouillard, L | 1 |
| Labopin, M | 1 |
| Meloni, G | 1 |
| Polge, E | 1 |
| Gorin, NC | 1 |
| Frassoni, F | 1 |
| Las Heras, G | 1 |
| Ribera, JM | 1 |
| Granada, I | 1 |
| Millá, F | 1 |
| Donhuijsen-Ant, R | 1 |
| Schadeck-Gressel, C | 1 |
| Schmidt, U | 1 |
| Löffler, H | 1 |
| Westerhausen, M | 1 |
| Leder, LD | 1 |
| Puccio, CA | 1 |
| Feldman, EJ | 1 |
| Arlin, ZA | 1 |
| Simon, JH | 1 |
| Tebbi, CK | 1 |
| Freeman, AI | 1 |
| Brecher, ML | 1 |
| Green, DM | 1 |
| Sandberg, AA | 1 |
2 reviews available for amsacrine and Leukemia, Megakaryoblastic, Acute
| Article | Year |
|---|---|
Acute megakaryoblastic leukemia: a case report.
Topics: Acid Phosphatase; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyta | 1990 |
Acute megakaryoblastic leukemia associated with mosaic Down's syndrome.
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 17; Clone Cells; | 1987 |
3 other studies available for amsacrine and Leukemia, Megakaryoblastic, Acute
| Article | Year |
|---|---|
Comparison of BAVC to BuCy regimens in autologous stem cell transplantation for adult patients with acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Carmus | 2004 |
[Acute myeloblastic leukemia 5q-. Clinical and cytogenetic remission by means of intensive chemotherapy].
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human, | 1991 |
Amsacrine is safe in patients with ventricular ectopy.
Topics: Aged; Amsacrine; Cardiac Complexes, Premature; Cytarabine; Drug Therapy, Combination; Electrocardiog | 1988 |