amsacrine has been researched along with Kidney Neoplasms in 6 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Kidney Neoplasms: Tumors or cancers of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mean terminal plasma half-life for total 14C ranged from 34 hr in patients with normal organ function to 46 hr in patients with severe liver disease." | 1.27 | Human pharmacokinetics of a new acridine derivative, 4'-(9-acridinylamino)methanesulfon-m-anisidide (NSC 249992). ( Benjamin, RS; Friedman, J; Gutterman, JU; Hall, SW; Legha, SS; Loo, TL, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hall, SW | 1 |
| Friedman, J | 1 |
| Legha, SS | 1 |
| Benjamin, RS | 1 |
| Gutterman, JU | 1 |
| Loo, TL | 1 |
| Trump, DL | 1 |
| Loening, S | 1 |
| Ahmed, SW | 1 |
| Wajsman, Z | 1 |
| Earhart, RH | 1 |
| Elson, PJ | 1 |
| Rosenthal, SN | 1 |
| Hahn, RG | 1 |
| Slayton, RE | 1 |
| Amrein, PC | 1 |
| Coleman, M | 1 |
| Richards, F | 1 |
| Poulin, RF | 1 |
| Berkowitz, I | 1 |
| Kennedy, BJ | 1 |
| Green, M | 1 |
| Herschkopf, R | 1 |
| Rafla, S | 1 |
| Schneider, RJ | 1 |
| Woodcock, TM | 1 |
| Yagoda, A | 1 |
| Laurençot, CM | 1 |
| Scheffer, GL | 1 |
| Scheper, RJ | 1 |
| Shoemaker, RH | 1 |
6 other studies available for amsacrine and Kidney Neoplasms
| Article | Year |
|---|---|
Human pharmacokinetics of a new acridine derivative, 4'-(9-acridinylamino)methanesulfon-m-anisidide (NSC 249992).
Topics: Aminoacridines; Amsacrine; Bile; Drug Evaluation; Half-Life; Humans; Kidney Neoplasms; Kinetics; Leu | 1983 |
Phase II study of amsacrine (AMSA) in previously treated patients with advanced transitional cell carcinoma of the urothelium: a National Bladder Cancer Collaborative Group A study.
Topics: Aminoacridines; Amsacrine; Carcinoma, Transitional Cell; Drug Evaluation; Epithelium; Humans; Kidney | 1983 |
Phase II study of PALA and AMSA in advanced renal cell carcinoma.
Topics: Adenocarcinoma; Aminoacridines; Amsacrine; Antimetabolites, Antineoplastic; Antineoplastic Agents; A | 1983 |
Phase II study of amsacrine in metastatic renal cell carcinoma: a Cancer and Leukemia Group B study.
Topics: Adenocarcinoma; Adult; Aged; Aminoacridines; Amsacrine; Bone Marrow; Drug Evaluation; Female; Humans | 1983 |
Phase II trial of 4'-(9-acridinylamino)methanesulfon-m-anisidide (AMSA) in patients with metastatic hypernephroma.
Topics: Adenocarcinoma; Adult; Aged; Aminoacridines; Amsacrine; Drug Evaluation; Female; Humans; Kidney Neop | 1980 |
Increased LRP mRNA expression is associated with the MDR phenotype in intrinsically resistant human cancer cell lines.
Topics: Amsacrine; Antineoplastic Agents; ATP-Binding Cassette Transporters; Cell Nucleus; Cisplatin; Coloni | 1997 |