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amsacrine and Hematologic Diseases

amsacrine has been researched along with Hematologic Diseases in 6 studies

Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.

Hematologic Diseases: Disorders of the blood and blood forming tissues.

Research Excerpts

ExcerptRelevanceReference
"A total of 70 patients with malignant lymphomas refractory to one or more chemotherapeutic regimens were treated with iv amsacrines (m-AMSA and m-AMSA lactate)."7.67Phase II study with amsacrines (m-AMSA and m-AMSA lactate) in refractory lymphomas. ( Bajetta, E; Bonadonna, G; Buzzoni, R; Gasparini, G; Piotti, P; Villani, F; Viviani, S, 1985)
"A total of 70 patients with malignant lymphomas refractory to one or more chemotherapeutic regimens were treated with iv amsacrines (m-AMSA and m-AMSA lactate)."3.67Phase II study with amsacrines (m-AMSA and m-AMSA lactate) in refractory lymphomas. ( Bajetta, E; Bonadonna, G; Buzzoni, R; Gasparini, G; Piotti, P; Villani, F; Viviani, S, 1985)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tan, RM1
Quah, TC1
Aung, L1
Liang, S1
Kirk, RC1
Yeoh, AE1
Goldman, A1
Malpas, JS1
Rybak, ME1
Anderson, JR1
Poulin, RF1
Amrein, PC1
Canellos, GP1
Gottlieb, AJ1
Bajetta, E1
Buzzoni, R1
Viviani, S1
Villani, F1
Piotti, P1
Gasparini, G1
Bonadonna, G1
Zittoun, R2
Bury, J1
Stryckmans, P1
Lowenberg, B1
Peetermans, M1
Rozendaal, KY1
Haanen, C1
Kerkhofs, M1
Jehn, U1
Willemze, R1

Reviews

1 review available for amsacrine and Hematologic Diseases

ArticleYear
m-AMSA: a review of clinical data.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:6

    Topics: Acute Disease; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Drug Evalu

1985

Trials

1 trial available for amsacrine and Hematologic Diseases

ArticleYear
Phase II trial of m-AMSA therapy in refractory Hodgkin's disease and non-Hodgkin's lymphoma: Cancer and Leukemia Group B Study 7972.
    Cancer treatment reports, 1986, Volume: 70, Issue:10

    Topics: Aged; Amsacrine; Clinical Trials as Topic; Drug Evaluation; Female; Hematologic Diseases; Hodgkin Di

1986

Other Studies

4 other studies available for amsacrine and Hematologic Diseases

ArticleYear
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and

2007
Phase I and II study of AMSA in childhood tumours.
    Cancer chemotherapy and pharmacology, 1982, Volume: 9, Issue:1

    Topics: Adolescent; Aminoacridines; Amsacrine; Antineoplastic Agents; Child; Child, Preschool; Drug Administ

1982
Phase II study with amsacrines (m-AMSA and m-AMSA lactate) in refractory lymphomas.
    Cancer treatment reports, 1985, Volume: 69, Issue:9

    Topics: Adult; Aminoacridines; Amsacrine; Drug Evaluation; Female; Hematologic Diseases; Hodgkin Disease; Hu

1985
Amsacrine with high-dose cytarabine in acute leukemia.
    Cancer treatment reports, 1985, Volume: 69, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemother

1985