amsacrine has been researched along with Heart Failure in 2 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seven patients developed clinical congestive heart failure." | 1.26 | Cardiac abnormalities after AMSA administration. ( Mangiacasale, D; Miller, DR; Steinherz, LJ; Steinherz, PG; Tan, C, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steinherz, LJ | 1 |
| Steinherz, PG | 1 |
| Mangiacasale, D | 1 |
| Tan, C | 1 |
| Miller, DR | 1 |
| Thomas, X | 1 |
| Fiere, D | 1 |
| Archimbaud, E | 1 |
2 other studies available for amsacrine and Heart Failure
| Article | Year |
|---|---|
Cardiac abnormalities after AMSA administration.
Topics: Adolescent; Adult; Aminoacridines; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Ch | 1982 |
Influence of increased body mass index on drug toxicity in patients with acute promyelocytic leukemia.
Topics: Adult; Aged; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; | 1998 |