amsacrine has been researched along with Granuloma, Hodgkin in 9 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 70 patients with malignant lymphomas refractory to one or more chemotherapeutic regimens were treated with iv amsacrines (m-AMSA and m-AMSA lactate)." | 7.67 | Phase II study with amsacrines (m-AMSA and m-AMSA lactate) in refractory lymphomas. ( Bajetta, E; Bonadonna, G; Buzzoni, R; Gasparini, G; Piotti, P; Villani, F; Viviani, S, 1985) |
| "Amsacrine was administered to 73 evaluable patients with previously treated malignant lymphoma in the Southwest Oncology Group." | 7.66 | Phase II study of amsacrine (m-AMSA) in advanced lymphomas: a Southwest Oncology Group study. ( Jones, SE; Ryan, DH; Weick, JK, 1983) |
| "A total of 70 patients with malignant lymphomas refractory to one or more chemotherapeutic regimens were treated with iv amsacrines (m-AMSA and m-AMSA lactate)." | 3.67 | Phase II study with amsacrines (m-AMSA and m-AMSA lactate) in refractory lymphomas. ( Bajetta, E; Bonadonna, G; Buzzoni, R; Gasparini, G; Piotti, P; Villani, F; Viviani, S, 1985) |
| "Amsacrine was administered to 73 evaluable patients with previously treated malignant lymphoma in the Southwest Oncology Group." | 3.66 | Phase II study of amsacrine (m-AMSA) in advanced lymphomas: a Southwest Oncology Group study. ( Jones, SE; Ryan, DH; Weick, JK, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bramwell, VH | 1 |
| Holdener, EE | 1 |
| Siegenthaler, P | 1 |
| Ten Bokkel Huinink, W | 1 |
| Bruntsch, U | 1 |
| Renard, J | 1 |
| van Glabbeke, M | 1 |
| Case, DC | 1 |
| Weick, JK | 1 |
| Jones, SE | 1 |
| Ryan, DH | 1 |
| Ahmann, FR | 1 |
| Meyskens, FL | 1 |
| Moon, TE | 1 |
| Durie, BG | 1 |
| Salmon, SE | 1 |
| Dreyfus, F | 1 |
| Leblond, V | 1 |
| Belanger, C | 1 |
| Gabarre, J | 1 |
| Sutton, L | 1 |
| Boccaccio, C | 1 |
| Quarre, MC | 1 |
| Ribrag, V | 1 |
| Goy, A | 1 |
| Rybak, ME | 1 |
| Anderson, JR | 1 |
| Poulin, RF | 1 |
| Amrein, PC | 1 |
| Canellos, GP | 1 |
| Gottlieb, AJ | 1 |
| Piotti, P | 2 |
| Villani, F | 2 |
| Comazzi, R | 1 |
| Lacaita, G | 1 |
| Guindani, A | 1 |
| Bajetta, E | 1 |
| Buzzoni, R | 1 |
| Viviani, S | 1 |
| Gasparini, G | 1 |
| Bonadonna, G | 1 |
| Keller, AM | 1 |
| Tsiatis, AA | 1 |
| Neiman, RS | 1 |
| Glick, JH | 1 |
| Mann, RB | 1 |
1 trial available for amsacrine and Granuloma, Hodgkin
| Article | Year |
|---|---|
Phase II trial of m-AMSA therapy in refractory Hodgkin's disease and non-Hodgkin's lymphoma: Cancer and Leukemia Group B Study 7972.
Topics: Aged; Amsacrine; Clinical Trials as Topic; Drug Evaluation; Female; Hematologic Diseases; Hodgkin Di | 1986 |
8 other studies available for amsacrine and Granuloma, Hodgkin
| Article | Year |
|---|---|
Phase II study of amsacrine in refractory lymphomas. A report of the EORTC Early Clinical Trials Group.
Topics: Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Female; | 1984 |
m-AMSA: phase II trial in advanced lymphoma and leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Bone Marro | 1984 |
Phase II study of amsacrine (m-AMSA) in advanced lymphomas: a Southwest Oncology Group study.
Topics: Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Hodgkin | 1983 |
In vitro chemosensitivities of human tumor stem cells to the Phase II drug 4'-(9-acridinylamino)methanesulfon-m-anisidide and prospective in vivo correlations.
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Cells, Cultured; Drug Evaluation; Female; Genital | 1982 |
Peripheral blood stem cell collection and autografting in high risk lymphomas.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Blood Component Removal; Blood Tra | 1992 |
Cardiac function evaluation in AMSA-treated patients.
Topics: Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Electrocardiography; | 1985 |
Phase II study with amsacrines (m-AMSA and m-AMSA lactate) in refractory lymphomas.
Topics: Adult; Aminoacridines; Amsacrine; Drug Evaluation; Female; Hematologic Diseases; Hodgkin Disease; Hu | 1985 |
m-AMSA in refractory lymphoma. A phase II trial of the Eastern Cooperative Oncology Group.
Topics: Adolescent; Adult; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Drug Evaluation; Hodgkin | 1985 |