amsacrine has been researched along with Graft vs Host Disease in 10 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Strategies to reduce recurrence are urgently required." | 3.01 | Augmented Reduced-Intensity Regimen Does Not Improve Postallogeneic Transplant Outcomes in Acute Myeloid Leukemia. ( Andrew, G; Byrne, J; Craddock, C; Crawley, C; Dillon, R; Freeman, SD; Gilleece, M; Hodgkinson, A; Hunter, A; Jackson, A; Khan, N; Loke, J; Malladi, R; Mason, J; McCarthy, N; Nagra, S; Parker, A; Pavlu, J; Peniket, A; Potter, V; Protheroe, R; Salim, R; Siddique, S; Tholouli, E; Vyas, P; Wheatley, K; Wilson, K, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Craddock, C | 1 |
| Jackson, A | 1 |
| Loke, J | 1 |
| Siddique, S | 1 |
| Hodgkinson, A | 1 |
| Mason, J | 1 |
| Andrew, G | 1 |
| Nagra, S | 1 |
| Malladi, R | 1 |
| Peniket, A | 1 |
| Gilleece, M | 1 |
| Salim, R | 1 |
| Tholouli, E | 1 |
| Potter, V | 1 |
| Crawley, C | 1 |
| Wheatley, K | 1 |
| Protheroe, R | 1 |
| Vyas, P | 1 |
| Hunter, A | 1 |
| Parker, A | 1 |
| Wilson, K | 1 |
| Pavlu, J | 1 |
| Byrne, J | 1 |
| Dillon, R | 1 |
| Khan, N | 1 |
| McCarthy, N | 1 |
| Freeman, SD | 1 |
| Krejci, M | 1 |
| Doubek, M | 1 |
| Dusek, J | 1 |
| Brychtova, Y | 1 |
| Racil, Z | 1 |
| Navratil, M | 1 |
| Tomiska, M | 1 |
| Horky, O | 1 |
| Pospisilova, S | 1 |
| Mayer, J | 1 |
| Feliu, J | 1 |
| Clay, J | 1 |
| Raj, K | 1 |
| Barber, L | 1 |
| Devlia, V | 1 |
| Shaw, B | 1 |
| Pagliuca, A | 1 |
| Mufti, G | 1 |
| Pfrepper, C | 1 |
| Klink, A | 1 |
| Behre, G | 1 |
| Schenk, T | 1 |
| Franke, GN | 1 |
| Jentzsch, M | 1 |
| Schwind, S | 1 |
| Al-Ali, HK | 1 |
| Hochhaus, A | 1 |
| Niederwieser, D | 1 |
| Sayer, HG | 1 |
| Malard, F | 1 |
| Labopin, M | 1 |
| Stuhler, G | 1 |
| Bittenbring, J | 1 |
| Ganser, A | 1 |
| Tischer, J | 2 |
| Michallet, M | 1 |
| Kröger, N | 1 |
| Schmid, C | 2 |
| Huynh, A | 1 |
| Hallek, M | 1 |
| Savani, BN | 1 |
| Mohty, M | 1 |
| Nagler, A | 1 |
| Schleuning, M | 1 |
| Holler, E | 1 |
| Haude, KH | 1 |
| Braess, J | 1 |
| Haferlach, C | 1 |
| Baurmann, H | 1 |
| Oruzio, D | 1 |
| Hahn, J | 1 |
| Spiekermann, K | 1 |
| Schlimok, G | 1 |
| Schwerdtfeger, R | 1 |
| Buechner, T | 1 |
| Hiddemann, W | 1 |
| Kolb, HJ | 1 |
| Saure, C | 1 |
| Schroeder, T | 1 |
| Zohren, F | 1 |
| Groten, A | 1 |
| Bruns, I | 1 |
| Czibere, A | 1 |
| Galonska, L | 1 |
| Kondakci, M | 1 |
| Weigelt, C | 1 |
| Fenk, R | 1 |
| Germing, U | 1 |
| Haas, R | 1 |
| Kobbe, G | 1 |
| Wernstedt, P | 1 |
| Brune, M | 1 |
| Andersson, PO | 1 |
| Gustavsson, B | 1 |
| Stockelberg, D | 1 |
| Wadenvik, H | 1 |
| Fukushima, T | 1 |
| Kuriyama, K | 1 |
| Yoshida, S | 1 |
| Nagai, K | 1 |
| Miyazaki, Y | 1 |
| Moriuti, Y | 1 |
| Tomonaga, M | 1 |
| Michel, G | 1 |
| Leverger, G | 1 |
| Leblanc, T | 1 |
| Nelken, B | 1 |
| Baruchel, A | 1 |
| Landman-Parker, J | 1 |
| Thuret, I | 1 |
| Bergeron, C | 1 |
| Bordigoni, P | 1 |
| Esperou-Bourdeau, H | 1 |
| Perel, Y | 1 |
| Vannier, JP | 1 |
| Schaison, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Reduced Intensity Conditioning With Fludarabine and Busulfan Versus Fludarabine and Melphalan Before Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Randomised, Single-Center, Phase III Study[NCT05674539] | Phase 3 | 200 participants (Anticipated) | Interventional | 2022-12-28 | Recruiting | ||
| Multicenter Protocol in Treating Patients With Childhood Acute Myeloid Leukemia. Randomized Study of Maintenance Treatment With Interleukin-2[NCT00149162] | Phase 3 | 580 participants (Anticipated) | Interventional | 2005-03-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for amsacrine and Graft vs Host Disease
| Article | Year |
|---|---|
Augmented Reduced-Intensity Regimen Does Not Improve Postallogeneic Transplant Outcomes in Acute Myeloid Leukemia.
Topics: Adult; Aged; Amsacrine; Busulfan; Cytarabine; Female; Graft vs Host Disease; Humans; Immunosuppressi | 2021 |
Early allo-SCT for AML with a complex aberrant karyotype--results from a prospective pilot study.
Topics: Abnormal Karyotype; Acute Disease; Adolescent; Adult; Amsacrine; Antilymphocyte Serum; Antineoplasti | 2012 |
Upfront allogeneic blood stem cell transplantation for patients with high-risk myelodysplastic syndrome or secondary acute myeloid leukemia using a FLAMSA-based high-dose sequential conditioning regimen.
Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; | 2012 |
Allogeneic bone marrow transplantation vs aggressive post-remission chemotherapy for children with acute myeloid leukemia in first complete remission. A prospective study from the French Society of Pediatric Hematology and Immunology (SHIP).
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation | 1996 |
6 other studies available for amsacrine and Graft vs Host Disease
| Article | Year |
|---|---|
Combination of fludarabine, amsacrine, and cytarabine followed by reduced-intensity conditioning and allogeneic hematopoietic stem cell transplantation in patients with high-risk acute myeloid leukemia.
Topics: Adult; Amsacrine; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; C | 2013 |
Transplant-acquired food allergy (TAFA) following cord blood stem cell transplantation in two adult patients with haematological malignancies.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cord Bl | 2014 |
Risk factors for outcome in refractory acute myeloid leukemia patients treated with a combination of fludarabine, cytarabine, and amsacrine followed by a reduced-intensity conditioning and allogeneic stem cell transplantation.
Topics: Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; C | 2016 |
Sequential Intensified Conditioning Regimen Allogeneic Hematopoietic Stem Cell Transplantation in Adult Patients with Intermediate- or High-Risk Acute Myeloid Leukemia in Complete Remission: A Study from the Acute Leukemia Working Party of the European Gr
Topics: Adolescent; Adult; Aged; Allografts; Amsacrine; Bone Marrow Transplantation; Busulfan; Cyclophospham | 2017 |
Favorable outcome with STI571 (imatinib mesylate) and allogeneic stem cell transplantation in a case of Ph+ chemorefractory acute lymphocytic leukaemia.
Topics: Adult; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; | 2002 |
[Allogeneic bone marrow transplantation for two patients with acute myeloid leukemia with trilineage myelodysplasia (T-MDS)].
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combi | 1994 |