amsacrine has been researched along with Eye Cancer, Retinoblastoma in 4 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the apoptotic effect induced in human retinoblastoma Y79 cells by camptothecin, etoposide, and amsacrine, to examine the effect of these drugs on the expression of many apoptosis-related modulators, and to test the antiapoptotic effect exerted by insulin-like growth factor-I (IGF-I)." | 3.70 | Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors. ( Carabillò, M; Giuliano, M; Lauricella, M; Tesoriere, G; Vassallo, E; Vento, R, 1998) |
| "Camptothecin was found to be the most effective compound." | 1.30 | Increased cyclin E level in retinoblastoma cells during programmed cell death. ( Carabillò, M; Emanuele, S; Giuliano, M; Lauricella, M; Tesoriere, G; Vento, R, 1998) |
| "This suggests that retinoblastoma is a chemosensitive tumour and therefore adjuvant chemotherapy may have a role in children with retinoblastoma who at diagnosis are thought to be at high risk of developing metastatic disease." | 1.27 | Chemotherapy in metastatic retinoblastoma. ( Hungerford, JL; Kingston, JE; Plowman, PN, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giuliano, M | 3 |
| Lauricella, M | 3 |
| Vassallo, E | 1 |
| Carabillò, M | 2 |
| Vento, R | 3 |
| Tesoriere, G | 3 |
| Emanuele, S | 2 |
| Kingston, JE | 1 |
| Hungerford, JL | 1 |
| Plowman, PN | 1 |
4 other studies available for amsacrine and Eye Cancer, Retinoblastoma
| Article | Year |
|---|---|
Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors.
Topics: Amsacrine; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Cell Survival; Cyclin-Dependent Kina | 1998 |
Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells.
Topics: Amsacrine; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Butyrates; Butyric A | 1998 |
Increased cyclin E level in retinoblastoma cells during programmed cell death.
Topics: Amsacrine; Apoptosis; Camptothecin; Cyclin A; Cyclin E; Enzyme Inhibitors; Etoposide; Humans; Interl | 1998 |
Chemotherapy in metastatic retinoblastoma.
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cisplatin; Cyclophosphamide; Eye N | 1987 |