amsacrine has been researched along with Experimental Neoplasms in 14 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antitumor activity and toxic effect of AMSA were studied in Lewis lung carcinoma (3LL) at various stages of growth." | 1.27 | Influence of scheduling on therapeutic and toxic effect of AMSA in Lewis lung carcinoma. ( Badaracco, G; Greco, C; Zupi, G, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamato, M | 1 |
| Takeuchi, Y | 1 |
| Hashigaki, K | 1 |
| Ikeda, Y | 1 |
| Chang, MR | 1 |
| Takeuchi, K | 1 |
| Matsushima, M | 1 |
| Tsuruo, T | 1 |
| Tashiro, T | 1 |
| Tsukagoshi, S | 1 |
| Deady, LW | 1 |
| Rodemann, T | 1 |
| Zhuang, L | 1 |
| Baguley, BC | 4 |
| Denny, WA | 3 |
| Kalirajan, R | 1 |
| Gaurav, K | 1 |
| Pandiselvi, A | 1 |
| Gowramma, B | 1 |
| Sankar, S | 1 |
| Arrick, BA | 1 |
| Nathan, CF | 1 |
| Greco, C | 1 |
| Zupi, G | 1 |
| Badaracco, G | 1 |
| Sordillo, PP | 1 |
| Helson, L | 1 |
| Lesser, M | 1 |
| Drewinko, B | 1 |
| Yang, LY | 1 |
| Barlogie, B | 1 |
| Dumont, P | 1 |
| Atassi, G | 1 |
| Tagnon, HJ | 1 |
| Stephens, TC | 1 |
| Peacock, JH | 1 |
| Johnson, RK | 1 |
| Wodinsky, I | 1 |
| Swiniarski, J | 1 |
| Meaney, KF | 1 |
| Clement, JJ | 1 |
| Rewcastle, GW | 1 |
| Wilson, WR | 2 |
| Grove, WR | 1 |
| DeLap, LW | 1 |
| Grillo-López, AJ | 1 |
| Finlay, GJ | 1 |
1 review available for amsacrine and Experimental Neoplasms
| Article | Year |
|---|---|
Glutathione metabolism as a determinant of therapeutic efficacy: a review.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Biological Transport; Carmustine; Cycloph | 1984 |
13 other studies available for amsacrine and Experimental Neoplasms
| Article | Year |
|---|---|
Synthesis and antitumor activity of fused tetracyclic quinoline derivatives. 1.
Topics: Animals; Cell Line; Cell Survival; Chemical Phenomena; Chemistry; Colonic Neoplasms; DNA; DNA Topois | 1989 |
Synthesis and cytotoxic activity of carboxamide derivatives of benzo[b][1,6]naphthyridines.
Topics: Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Humans; Mice; Napht | 2003 |
Novel Thiazine Substituted 9-Anilinoacridines: Synthesis, Antitumour Activity and Structure Activity Relationships.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relation | 2019 |
Influence of scheduling on therapeutic and toxic effect of AMSA in Lewis lung carcinoma.
Topics: Aminoacridines; Amsacrine; Animals; Drug Administration Schedule; Female; Hematopoiesis; Leukopenia; | 1983 |
Evaluation of 4'-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA, NSC 249992) on human tumors in nude mice.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Doxorubicin; Drug Evaluation, Preclinical | 1980 |
Lethal activity and kinetic response of cultured human cells to 4'-(9-acridinylamino)methanesulfon-m-anisidine.
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cell Surviva | 1982 |
Combination chemotherapy with AMSA on L1210 leukaemia and B16 melanoma.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Carmustine; Dacarbazine; Drug Therapy, Co | 1981 |
Clonal variation in the sensitivity of B16 melanoma to m-AMSA.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Survival; Clone Cells; Lung Neoplasm | 1982 |
Interaction of gamma-irradiation with two new antineoplastic agents, aziridinylbenzoquinone (AZQ) and 4'- (acridinylamino)methanesulfon-m-anisidide (AMSA), in murine tumors in vivo.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Cell | 1979 |
Amsacrine analogues with extended chromophores: DNA binding and anti-tumour activity.
Topics: Amsacrine; Animals; Antineoplastic Agents; DNA; Mice; Neoplasms, Experimental; Structure-Activity Re | 1987 |
In vitro and in vivo assessment of activity of new anilino-substituted analogues of amsacrine against Lewis lung carcinoma.
Topics: Amsacrine; Animals; DNA; Female; Lung Neoplasms; Mice; Mice, Inbred DBA; Neoplasms, Experimental; St | 1986 |
CI-921: an analog of amsacrine with experimental activity against solid tumors.
Topics: Aminoacridines; Amsacrine; Animals; Cell Cycle; Cells, Cultured; Metabolic Clearance Rate; Mice; Neo | 1986 |
Cytokinetic resistance of Lewis lung carcinoma to cyclophosphamide and the amsacrine derivative CI-921.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cyclophosphamide; Drug Resistance; | 1986 |