amsacrine has been researched along with Disease Models, Animal in 6 studies
Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent.
amsacrine : A sulfonamide that is N-phenylmethanesulfonamide substituted by a methoxy group at position 3 and an acridin-9-ylamino group at position 4. It exhibits antineoplastic activity.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, scarring sometimes still occurs." | 5.51 | The DNA topoisomerase II inhibitor amsacrine as a novel candidate adjuvant in a model of glaucoma filtration surgery. ( Akaishi, T; Kokubun, T; Nakamura, M; Nakazawa, T; Omodaka, K; Sato, K; Saya, H; Shiga, Y; Shimazaki, A; Tsuda, S; Yamamoto, K, 2019) |
| "However, scarring sometimes still occurs." | 1.51 | The DNA topoisomerase II inhibitor amsacrine as a novel candidate adjuvant in a model of glaucoma filtration surgery. ( Akaishi, T; Kokubun, T; Nakamura, M; Nakazawa, T; Omodaka, K; Sato, K; Saya, H; Shiga, Y; Shimazaki, A; Tsuda, S; Yamamoto, K, 2019) |
| " The LD50 values observed in normal and leukemic Brown-Norway rats were 26." | 1.27 | AMSA: in vivo log cell kill for leukemic clonogenic cells versus toxicity for normal hemopoietic stem cells in a rat model for human acute myelocytic leukemia (BNML). ( Hagenbeek, A; Martens, AC, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Yamamoto, K | 1 |
| Kokubun, T | 1 |
| Sato, K | 1 |
| Akaishi, T | 1 |
| Shimazaki, A | 1 |
| Nakamura, M | 1 |
| Shiga, Y | 1 |
| Tsuda, S | 1 |
| Omodaka, K | 1 |
| Saya, H | 1 |
| Nakazawa, T | 1 |
| Hagenbeek, A | 1 |
| Martens, AC | 1 |
| Leopold, WR | 1 |
| Corbett, TH | 1 |
| Griswold, DP | 1 |
| Plowman, J | 1 |
| Baguley, BC | 1 |
1 review available for amsacrine and Disease Models, Animal
| Article | Year |
|---|---|
DNA topoisomerase II inhibitors.
Topics: Amsacrine; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Etoposide; Evidence-Based Med | 2000 |
5 other studies available for amsacrine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The DNA topoisomerase II inhibitor amsacrine as a novel candidate adjuvant in a model of glaucoma filtration surgery.
Topics: Amsacrine; Animals; Callithrix; Cicatrix; Conjunctiva; Disease Models, Animal; DNA Topoisomerases, T | 2019 |
AMSA: in vivo log cell kill for leukemic clonogenic cells versus toxicity for normal hemopoietic stem cells in a rat model for human acute myelocytic leukemia (BNML).
Topics: Amsacrine; Animals; Clone Cells; Colony-Forming Units Assay; Disease Models, Animal; Hematopoietic S | 1986 |
Experimental antitumor activity of the amsacrine analogue CI-921.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Line; Colonic Neoplasms; Disease Models, Animal; Dru | 1987 |